Seth Blumberg, MD, PhD
Assistant Professor
Medicine
School of Medicine
seth.blumberg@ucsf.edu 415-502-1366
Research: My research focuses on developing and applying data-driven computational models of infectious diseases that exhibit the potential of elimination (i.e. R < 1). A key goal has been to elucidate risk factors that tip the balance between disease quiescence and emergence. This involves quantification of the impact of patient-specific or population-wide control interventions.
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Applications include enhancing trachoma elimination programs, mitigating the impact of SARS-CoV-2 in congregate settings, characterizing the transmission dynamics of healthcare associated infections, and identifying factors responsible for the emergence of antibiotic resistance. My involvement in direct patient care provides a practical perspective of the investigations and metrics that have an immediate impact on clinical guidelines and public health.
I am fortunate to be based within the Francis I. Proctor Foundation. The Foundation’s interdisciplinary approach toward alleviating the global burden of infectious disease is innovative, impactful, and intellectually engaging.
Clinical: I am an attending physician for the St Marys Medical Center Hospitalist Service, and particularly enjoy the opportunity to work with residents and medical students. I also serve as an infectious disease consultant for the UCSF hospitals.
Education & Training
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- DEI champion training University of California, San Francisco 12/2022
- Infectious disease fellowship New York University Langone Medical Center 06/2019
- Internal medicine residency St Marys Medical Center 06/2017
- RAPIDD postdoc NIH Fogarty International Center 09/2012
- Internal medicine internship Iowa Methodist Medical Center 06/2009
- MD PhD Biophysics University of Michigan 05/2008
- BSc Engineering and applied science California Institute of Technology 06/1997
Interests
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- mathematical modeling
- healthcare associated infections
- disease elimination
- antimicrobial resistance
- infectious diseases
- internal medicine
- disease emergence
- neglected tropics diseases
- computational epidemiology
Websites
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- MINDSCAPE group (mindscape.team)
Publications (46)
Top publication keywords:
TrachomaDisease OutbreaksAzithromycinAnti-Bacterial AgentsNeglected DiseasesDisease EradicationSmallpoxOnchocerciasisSchistosomiasisMass Drug AdministrationMeaslesTropical MedicineForecastingLeishmaniasis, VisceralCommunicable Disease Control
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Strength and durability of indirect protection against SARS-CoV-2 infection through vaccine and infection-acquired immunity.
medRxiv : the preprint server for health sciences 2024 Tan ST, Rodríguez-Barraquer I, Kwan AT, Blumberg S, Park HJ, Hutchinson J, Leidner D, Lewnard JA, Sears D, Lo NC -
Characterizing trachoma elimination using serology.
medRxiv : the preprint server for health sciences 2024 Kamau E, Ante-Testard PA, Gwyn S, Blumberg S, Abdalla Z, Aiemjoy K, Amza A, Aragie S, Arzika AM, Awoussi MS, Bailey RL, Butcher R, Callahan EK, Chaima D, Dawed AA, Saboyá Díaz MI, Domingo AS, Drakeley… -
Socioeconomic Disparities and the Prevalence of Antimicrobial Resistance.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2024 Cooper LN, Beauchamp AM, Ingle TA, Diaz MI, Wakene AD, Katterpalli C, Keller T, Walker C, Blumberg S, Kanjilal S, Chen JH, Radunsky AP, Most ZM, Hanna JJ, Perl TM, Lehmann CU, Medford RJ -
Accelerating Progress Towards the 2030 Neglected Tropical Diseases Targets: How Can Quantitative Modeling Support Programmatic Decisions?
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2024 Vasconcelos A, King JD, Nunes-Alves C, Anderson R, Argaw D, Basáñez MG, Bilal S, Blok DJ, Blumberg S, Borlase A, Brady OJ, Browning R, Chitnis N, Coffeng LE, Crowley EH, Cucunubá ZM, Cummings DAT, … -
District-Level Forecast of Achieving Trachoma Elimination as a Public Health Problem By 2030: An Ensemble Modelling Approach.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2024 Srivathsan A, Abdou A, Al-Khatib T, Apadinuwe SC, Badiane MD, Bucumi V, Chisenga T, Kabona G, Kabore M, Kanyi SK, Bella L, M'po N, Masika M, Minnih A, Sitoe HM, Mishra S, Olobio N, Omar FJ, Phiri I, …
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Temporal Trends in Phenotypic Macrolide and Nonmacrolide Resistance for Streptococcus pneumoniae Nasopharyngeal Samples Up to 36 Months after Mass Azithromycin Administration in a Cluster-Randomized Trial in Niger.
The American journal of tropical medicine and hygiene 2023 Hazel A, Arzika AM, Abdou A, Lebas E, Porco TC, Maliki R, Doan T, Lietman TM, Keenan JD, Blumberg S -
Rates of SARS-CoV-2 transmission between and into California state prisons.
medRxiv : the preprint server for health sciences 2023 Dubey P, Hoover CM, Lu P, Blumberg S, Porco TC, Parsons TL, Worden L -
Challenges in Forecasting Antimicrobial Resistance.
Emerging infectious diseases 2023 Pei S, Blumberg S, Vega JC, Robin T, Zhang Y, Medford RJ, Adhikari B, Shaman J, CDC MIND-Healthcare Program -
Aligning staff schedules, testing, and isolation reduces the risk of COVID-19 outbreaks in carceral and other congregate settings: A simulation study.
PLOS global public health 2023 Hoover CM, Skaff NK, Blumberg S, Fukunaga R -
Social Network Analysis of Ebola Virus Disease During the 2014 Outbreak in Sukudu, Sierra Leone.
Open forum infectious diseases 2022 Hazel A, Davidson MC, Rogers A, Barrie MB, Freeman A, Mbayoh M, Kamara M, Blumberg S, Lietman TM, Rutherford GW, Jones JH, Porco TC, Richardson ET, Kelly JD -
Evaluating and mitigating the potential indirect effect of COVID-19 on control programmes for seven neglected tropical diseases: a modelling study.
The Lancet. Global health 2022 Borlase A, Le Rutte EA, Castaño S, Blok DJ, Toor J, Giardina F, Davis EL, NTD Modelling Consortium -
Modeling scenarios for mitigating outbreaks in congregate settings.
PLoS computational biology 2022 Blumberg S, Lu P, Kwan AT, Hoover CM, Lloyd-Smith JO, Sears D, Bertozzi SM, Worden L -
Developing a COVID-19 WHO Clinical Progression Scale inpatient database from electronic health record data.
Journal of the American Medical Informatics Association : JAMIA 2022 Ramaswamy P, Gong JJ, Saleh SN, McDonald SA, Blumberg S, Medford RJ, Liu X -
Early identification of patients admitted to hospital for covid-19 at risk of clinical deterioration: model development and multisite external validation study.
BMJ (Clinical research ed.) 2022 Kamran F, Tang S, Otles E, McEvoy DS, Saleh SN, Gong J, Li BY, Dutta S, Liu X, Medford RJ, Valley TS, West LR, Singh K, Blumberg S, Donnelly JP, Shenoy ES, Ayanian JZ, Nallamothu BK, Sjoding MW, Wiens… -
Modeling transmission of pathogens in healthcare settings.
Current opinion in infectious diseases 2021 Stachel A, Keegan LT, Blumberg S, CDC MInD Healthcare Program -
Forecasting Trachoma Control and Identifying Transmission-Hotspots.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2021 Blumberg S, Prada JM, Tedijanto C, Deiner MS, Godwin WW, Emerson PM, Hooper PJ, Borlase A, Hollingsworth TD, Oldenburg CE, Porco TC, Arnold BF, Lietman TM -
Predicted Impact of COVID-19 on Neglected Tropical Disease Programs and the Opportunity for Innovation.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2021 Toor J, Adams ER, Aliee M, Amoah B, Anderson RM, Ayabina D, Bailey R, Basáñez MG, Blok DJ, Blumberg S, Borlase A, Rivera RC, Castaño MS, Chitnis N, Coffeng LE, Crump RE, Das A, Davis CN, Davis EL, … -
Implications of the COVID-19 pandemic in eliminating trachoma as a public health problem.
Transactions of the Royal Society of Tropical Medicine and Hygiene 2021 Blumberg S, Borlase A, Prada JM, Solomon AW, Emerson P, Hooper PJ, Deiner MS, Amoah B, Hollingsworth TD, Porco TC, Lietman TM -
Modelling trachoma post-2020: opportunities for mitigating the impact of COVID-19 and accelerating progress towards elimination.
Transactions of the Royal Society of Tropical Medicine and Hygiene 2021 Borlase A, Blumberg S, Callahan EK, Deiner MS, Nash SD, Porco TC, Solomon AW, Lietman TM, Prada JM, Hollingsworth TD -
The Impact of Different Types of Violence on Ebola Virus Transmission During the 2018-2020 Outbreak in the Democratic Republic of the Congo.
The Journal of infectious diseases 2020 Kelly JD, Wannier SR, Sinai C, Moe CA, Hoff NA, Blumberg S, Selo B, Mossoko M, Chowell-Puente G, Jones JH, Okitolonda-Wemakoy E, Rutherford GW, Lietman TM, Muyembe-Tamfum JJ, Rimoin AW, Porco TC, … -
Real-time monitoring the transmission potential of COVID-19 in Singapore, March 2020.
BMC medicine 2020 Tariq A, Lee Y, Roosa K, Blumberg S, Yan P, Ma S, Chowell G -
Real-time monitoring the transmission potential of COVID-19 in Singapore, March 2020.
medRxiv : the preprint server for health sciences 2020 Tariq A, Lee Y, Roosa K, Blumberg S, Yan P, Ma S, Chowell G -
The Effect of Anterior Corneal Astigmatism Orientation on Toric Intraocular Lens Outcomes.
Open Journal of Ophthalmology 2019 Eugene A. Lowry, Jonathan Li, Sundeep K. Kasi, Seth Blumberg, Priya Morjaria, Steven Schallhorn, Ayman Naseri -
Genotype-Specific Measles Transmissibility: A Branching Process Analysis.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2018 Ackley SF, Hacker JK, Enanoria WTA, Worden L, Blumberg S, Porco TC, Zipprich J -
Using Social Media to Characterize Public Sentiment Toward Medical Interventions Commonly Used for Cancer Screening: An Observational Study.
Journal of medical Internet research 2017 Metwally O, Blumberg S, Ladabaum U, Sinha SR -
The Effect of Contact Investigations and Public Health Interventions in the Control and Prevention of Measles Transmission: A Simulation Study.
PloS one 2016 Enanoria WT, Liu F, Zipprich J, Harriman K, Ackley S, Blumberg S, Worden L, Porco TC -
Risk Factors for Return to the Operating Room after Resident-Performed Cataract Surgery.
Seminars in ophthalmology 2016 Menda SA, Driver TH, Neiman AE, Blumberg S, Naseri A, Stewart JM -
Characterizing the transmissibility of cancer.
Journal of Clinical Oncology 2016 Seth Blumberg -
Vaccination Compliance and the US Measles Epidemic.
JAMA pediatrics 2015 Blumberg S, Enanoria WT, Porco TC -
Assessing Measles Transmission in the United States Following a Large Outbreak in California.
PLoS currents 2015 Blumberg S, Worden L, Enanoria W, Ackley S, Deiner M, Liu F, Gao D, Lietman T, Porco T -
The role of vaccination coverage, individual behaviors, and the public health response in the control of measles epidemics: an agent-based simulation for California.
BMC public health 2015 Liu F, Enanoria WT, Zipprich J, Blumberg S, Harriman K, Ackley SF, Wheaton WD, Allpress JL, Porco TC -
The distribution of the prevalence of ocular chlamydial infection in communities where trachoma is disappearing.
Epidemics 2015 Lietman TM, Gebre T, Abdou A, Alemayehu W, Emerson P, Blumberg S, Keenan JD, Porco TC -
Detecting differential transmissibilities that affect the size of self-limited outbreaks.
PLoS pathogens 2014 Blumberg S, Funk S, Pulliam JR -
Synthesizing data and models for the spread of MERS-CoV, 2013: key role of index cases and hospital transmission.
Epidemics 2014 Chowell G, Blumberg S, Simonsen L, Miller MA, Viboud C -
Identifying postelimination trends for the introduction and transmissibility of measles in the United States.
American journal of epidemiology 2014 Blumberg S, Enanoria WT, Lloyd-Smith JO, Lietman TM, Porco TC -
Antibiotic use as a tragedy of the commons: a cross-sectional survey.
Computational and mathematical methods in medicine 2014 O'Brien KS, Blumberg S, Enanoria WT, Ackley S, Sippl-Swezey N, Lietman TM -
Pathogen-host associations and predicted range shifts of human monkeypox in response to climate change in central Africa.
PloS one 2013 Thomassen HA, Fuller T, Asefi-Najafabady S, Shiplacoff JA, Mulembakani PM, Blumberg S, Johnston SC, Kisalu NK, Kinkela TL, Fair JN, Wolfe ND, Shongo RL, LeBreton M, Meyer H, Wright LL, Muyembe JJ, … -
Inference of R(0) and transmission heterogeneity from the size distribution of stuttering chains.
PLoS computational biology 2013 Blumberg S, Lloyd-Smith JO -
Using remote sensing to map the risk of human monkeypox virus in the Congo Basin.
EcoHealth 2010 Fuller T, Thomassen HA, Mulembakani PM, Johnston SC, Lloyd-Smith JO, Kisalu NK, Lutete TK, Blumberg S, Fair JN, Wolfe ND, Shongo RL, Formenty P, Meyer H, Wright LL, Muyembe JJ, Buermann W, Saatchi SS,… -
Major increase in human monkeypox incidence 30 years after smallpox vaccination campaigns cease in the Democratic Republic of Congo.
Proceedings of the National Academy of Sciences of the United States of America 2010 Rimoin AW, Mulembakani PM, Johnston SC, Lloyd Smith JO, Kisalu NK, Kinkela TL, Blumberg S, Thomassen HA, Pike BL, Fair JN, Wolfe ND, Shongo RL, Graham BS, Formenty P, Okitolonda E, Hensley LE, Meyer H… -
Concentration and length dependence of DNA looping in transcriptional regulation.
PloS one 2009 Han L, Garcia HG, Blumberg S, Towles KB, Beausang JF, Nelson PC, Phillips R -
Intrinsic curvature of DNA influences LacR-mediated looping.
Biophysical journal 2007 Goyal S, Lillian T, Blumberg S, Meiners JC, Meyhöfer E, Perkins NC -
Do femtonewton forces affect genetic function? A review.
Journal of biological physics 2006 Blumberg S, Pennington MW, Meiners JC -
Mg2+-induced compaction of single RNA molecules monitored by tethered particle microscopy.
Biophysical journal 2006 Newby Lambert M, Vöcker E, Blumberg S, Redemann S, Gajraj A, Meiners JC, Walter NG -
Three-dimensional characterization of tethered microspheres by total internal reflection fluorescence microscopy.
Biophysical journal 2005 Blumberg S, Gajraj A, Pennington MW, Meiners JC -
Disruption of protein-mediated DNA looping by tension in the substrate DNA.
Biophysical journal 2005 Blumberg S, Tkachenko AV, Meiners JC