Semil Choksi, PhD
Research Scientist
Biochemistry and Biophysics
School of Medicine

Education & Training

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• PhD Department of Genetics University of Cambridge

Publications (17)

Top publication keywords:
Genetic Association StudiesTranscription FactorsDrosophila melanogasterRegulatory Factor X Transcription FactorsForkhead Transcription FactorsTranscription, GeneticGene Expression Regulation, DevelopmentalCiliary Motility DisordersZebrafishGenomicsDrosophila ProteinsGene Regulatory NetworksZebrafish ProteinsCiliaEmbryo, Nonmammalian

• An RFX transcription factor regulates ciliogenesis in the closest living relatives of animals.
  Current biology : CB 2023 Coyle MC, Tajima AM, Leon F, Choksi SP, Yang A, Espinoza S, Hughes TR, Reiter JF, Booth DS, King N
• Vertebrate cells differentially interpret ciliary and extraciliary cAMP.
  Cell 2021 Truong ME, Bilekova S, Choksi SP, Li W, Bugaj LJ, Xu K, Reiter JF
• Flow-Cytometric Analysis and Purification of Airway Epithelial-Cell Subsets.
  American journal of respiratory cell and molecular biology 2021 Bonser LR, Koh KD, Johansson K, Choksi SP, Cheng D, Liu L, Sun DI, Zlock LT, Eckalbar WL, Finkbeiner WE, Erle DJ
• Evolutionary Proteomics Uncovers Ancient Associations of Cilia with Signaling Pathways.
  Developmental cell 2017 Sigg MA, Menchen T, Lee C, Johnson J, Jungnickel MK, Choksi SP, Garcia G, Busengdal H, Dougherty GW, Pennekamp P, Werner C, Rentzsch F, Florman HM, Krogan N, Wallingford JB, Omran H, Reiter JF
• Hsd11ß2 Is Enriched in Medulloblastoma and Generates Ciliary Oxysterols to Stimulate Hedgehog Signaling.
  International Journal of Radiation Oncology • Biology • Physics 2016 D. Raleigh, N. Sever, M.A. Sigg, F.R. Garcia-Gonzalo, P.K. Choksi, K.M. Hines, S.P. Choksi, A.L. Krup, J.G. McDonald, L. Xu, P.A. Beachy, J.F. Reiter

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• Mutations in CCDC11, which encodes a coiled-coil containing ciliary protein, causes situs inversus due to dysmotility of monocilia in the left-right organizer.
  Human mutation 2015 Narasimhan V, Hjeij R, Vij S, Loges NT, Wallmeier J, Koerner-Rettberg C, Werner C, Thamilselvam SK, Boey A, Choksi SP, Pennekamp P, Roy S, Omran H
• A function for the Joubert syndrome protein Arl13b in ciliary membrane extension and ciliary length regulation.
  Developmental biology 2014 Lu H, Toh MT, Narasimhan V, Thamilselvam SK, Choksi SP, Roy S
• Systematic discovery of novel ciliary genes through functional genomics in the zebrafish.
  Journal of Cell Science 2014 Semil P. Choksi, Deepak Babu, Doreen Lau, Xianwen Yu, Sudipto Roy
• Systematic discovery of novel ciliary genes through functional genomics in the zebrafish.
  Development (Cambridge, England) 2014 Choksi SP, Babu D, Lau D, Yu X, Roy S
• Switching on cilia: transcriptional networks regulating ciliogenesis.
  Development (Cambridge, England) 2014 Choksi SP, Lauter G, Swoboda P, Roy S
• Identification and characterization of the vertebrate motile ciliome.
  Cilia 2012 S Roy, S Choksi, D Babu, X Yu, D Lau, HK Ho, KN Wong, P Panse, L Hao, S Vij, S Chen
• Identifying gene regulatory networks that control adult regeneration in zebrafish.
  Developmental Biology 2009 Semil P. Choksi, Pallavi Panse, Wan Ying Leong, Sudipto Roy
• Corrigendum to “Specification of vertebrate slow-twitch muscle fiber fate by the transcriptional regulator Blimp1” [Dev. Biol. 324 (2008) 226–235].
  Developmental Biology 2009 Hoe Peng Liew, Semil P. Choksi, Kangli Noel Wong, Sudipto Roy
• Specification of vertebrate slow-twitch muscle fiber fate by the transcriptional regulator Blimp1.
  Developmental biology 2008 Liew HP, Choksi SP, Wong KN, Roy S
• Prospero acts as a binary switch between self-renewal and differentiation in Drosophila neural stem cells.
  Developmental cell 2006 Choksi SP, Southall TD, Bossing T, Edoff K, de Wit E, Fischer BE, van Steensel B, Micklem G, Brand AH
• Turning back the clock on neural progenitors.
  BioEssays : news and reviews in molecular, cellular and developmental biology 2004 Carr AR, Choksi SP, Brand AH
• amontillado, the Drosophila homolog of the prohormone processing protease PC2, is required during embryogenesis and early larval development.
  Genetics 2003 Rayburn LY, Gooding HC, Choksi SP, Maloney D, Kidd AR, Siekhaus DE, Bender M