Sei Lee, MD, MAS
Professor
Medicine
School of Medicine
Sei Lee is an Professor in the Division of Geriatrics and Senior Scholar for the San Francisco VA Quality Scholars fellowship. His research focuses on improving the targeting of preventive interventions in older adults to maximize benefits and minimize harms.
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Dr. Lee attended medical school at the University of Illinois-Rockford, then moved to UCSF where he completed Primary Care Internal Medicine residency and a Geriatric Medicine fellowship. He also completed the VA Quality Scholars fellowship, receiving advanced training in methodologies related to healthcare quality from the San Francisco VA and obtained a Master’s degree in clinical research from UCSF.
Dr. Lee joined the Division of Geriatrics faculty in 2007. Dr. Lee’s research examines how a patient’s health status can help individualize preventive and treatment decisions, with a special focus on diabetes care for frail nursing home residents. Dr. Lee is an expert in clinical prediction and has published research on predicting mortality, functional decline, dementia and pneumonia. In his clinical work, Dr. Lee supervises and trains residents, fellows and medical students while providing care for internal medicine and palliative care patients at the San Francisco Veterans Affairs Medical Center.
When not at work, he's usually trying to entertain his 3 kids. He enjoys commuting on his scooter, hiking and mountain biking.
Awards
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- Outstanding Committee Service Award, American Geriatrics Society, 2014
- Best Clinical-Decision Making Paper, American Geriatrics Society, 2012
- Merck/AGS New Investigator Award, American Geriatrics Society, 2012
- Beeson Scholar in Aging Research, National Institute on Aging and the American Federation of Aging Research, 2011
- Ann Internal Med Top Grade Reviewer, UCSF, 2010
- Hartford Foundation Center of Excellence Scholar, UCSF, 2010
- J Gen Internal Med Distinguished Reviewer, UCSF, 2009
- Hartford Foundation Outcomes Research Scholar, UCSF, 2008
- Commencement Speaker, University of Illinois, 1999
- King's College (London) Scholarship, University of Illinois, 1999
- Alpha Omega Alpha, University of Illinois, 1997
Education & Training
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- Diversity, Equity, and Inclusion Champion Training University of California 2019
- Cert Medicine (Advance Training in Clinical Research) University of California, San Francisco 2005
Grants and Projects
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- Improving Care for Nursing Home residents with Diabetes and Cognitive Impairment, NIH, 2020-2025
- Prognostic calculators for patients with Alzheimers disease and related dementias, NIH, 2018-2022
- Development and Validation of 10-Year Life Expectancy Calculators to Individualize Veterans? Prevention Decisions, NIH, 2017-2021
- Developing prognostic models for life expectancy and geriatric outcomes, NIH, 2015-2020
- Individualizing Treatment for Nursing Home Residents with Diabetes Mellitus, NIH, 2011-2015
Publications (83)
Top publication keywords:
Life ExpectancyIndependent LivingHypoglycemic AgentsActivities of Daily LivingDementiaCognitive DysfunctionDiabetes MellitusMortalityDiabetes Mellitus, Type 2Homes for the AgedBlood GlucoseMetforminEarly Detection of CancerHypoglycemiaNursing Homes
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Development and External Validation of Models to Predict Need for Nursing Home Level of Care in Community-Dwelling Older Adults With Dementia.
JAMA internal medicine 2024 Deardorff WJ, Jeon SY, Barnes DE, Boscardin WJ, Langa KM, Covinsky KE, Mitchell SL, Lee SJ, Smith AK -
Reply to: Disease latency and new-user versus prevalent-user cohort designs: Implications for pharmacoepidemiology in dementia.
Journal of the American Geriatrics Society 2023 Lee AK, Lee SJ, Dublin S -
Around the EQUATOR with Clin-STAR: Prediction modeling opportunities and challenges in aging research.
Journal of the American Geriatrics Society 2023 Deardorff WJ, Diaz-Ramirez LG, Boscardin WJ, Smith AK, Lee SJ -
Frequency of Screening for Colorectal Cancer by Predicted Life Expectancy Among Adults 76-85 Years.
JAMA 2023 Deardorff WJ, Lu K, Jing B, Jeon SY, Boscardin WJ, Fung KZ, Lee SJ -
Addressing the unique challenges in studies of long-term medication use and dementia risk.
Journal of the American Geriatrics Society 2023 Lee AK, Lee SJ, Dublin S
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Improving Clinical Applicability of Mortality Prediction Models Among Persons With Dementia-Reply.
JAMA internal medicine 2023 Deardorff WJ, Smith AK, Lee SJ -
Perioperative Risk Assessment and Avoiding Overuse of Anesthesia Care for Routine Cataract Surgery-Reply.
JAMA internal medicine 2023 Perumal D, Lee SJ, Chen CL -
Preoperative Factors Predict Memory Decline After Coronary Artery Bypass Grafting or Percutaneous Coronary Intervention in an Epidemiological Cohort of Older Adults.
Journal of the American Heart Association 2022 Tang AB, Diaz-Ramirez LG, Smith AK, Lee SJ, Whitlock EL -
Development and External Validation of a Mortality Prediction Model for Community-Dwelling Older Adults With Dementia.
JAMA internal medicine 2022 Deardorff WJ, Barnes DE, Jeon SY, Boscardin WJ, Langa KM, Covinsky KE, Mitchell SL, Whitlock EL, Smith AK, Lee SJ -
Development and validation of novel multimorbidity indices for older adults.
Journal of the American Geriatrics Society 2022 Steinman MA, Jing B, Shah SJ, Rizzo A, Lee SJ, Covinsky KE, Ritchie CS, Boscardin WJ -
Anesthesia Care for Cataract Surgery in Medicare Beneficiaries.
JAMA internal medicine 2022 Perumal D, Dudley RA, Gan S, Boscardin WJ, Gill A, Gelb AW, Lee SJ, Chen CL -
Fingerstick glucose monitoring by cognitive impairment status in Veterans Affairs nursing home residents with diabetes.
Journal of the American Geriatrics Society 2022 Nguyen B, Deardorff WJ, Shi Y, Jing B, Lee AK, Lee SJ -
A comprehensive prognostic tool for older adults: Predicting death, ADL disability, and walking disability simultaneously.
Journal of the American Geriatrics Society 2022 Lee AK, Diaz-Ramirez LG, Boscardin WJ, Smith AK, Lee SJ -
Do functional status and Medicare claims data improve the predictive accuracy of an electronic health record mortality index? Findings from a national Veterans Affairs cohort.
BMC geriatrics 2022 Deardorff WJ, Jing B, Jeon SY, Boscardin WJ, Lee AK, Fung KZ, Lee SJ -
Sliding scale insulin use in a national cohort study of nursing home residents with type 2 diabetes.
Journal of the American Geriatrics Society 2022 Lam K, Gan S, Nguyen B, Jing B, Lee SJ -
Glycemic treatment deintensification practices in nursing home residents with type 2 diabetes.
Journal of the American Geriatrics Society 2022 Lederle LI, Steinman MA, Jing B, Nguyen B, Lee SJ -
Mild cognitive impairment as a clinical and research outcome: Ready for prime time?
Journal of the American Geriatrics Society 2022 Deardorff WJ, Lee SJ -
Time to Benefit of Bisphosphonate Therapy for the Prevention of Fractures Among Postmenopausal Women With Osteoporosis: A Meta-analysis of Randomized Clinical Trials.
JAMA internal medicine 2022 Deardorff WJ, Cenzer I, Nguyen B, Lee SJ -
Predicting Life Expectancy to Target Cancer Screening Using Electronic Health Record Clinical Data.
Journal of general internal medicine 2021 Lee AK, Jing B, Jeon SY, Boscardin WJ, Lee SJ -
A Novel Metric for Developing Easy-to-Use and Accurate Clinical Prediction Models: The Time-cost Information Criterion.
Medical care 2021 Lee SJ, Smith AK, Diaz-Ramirez LG, Covinsky KE, Gan S, Chen CL, Boscardin WJ -
Mobile Health Intervention Promoting Physical Activity in Adults Post Cardiac Rehabilitation: Pilot Randomized Controlled Trial.
JMIR formative research 2021 Park LG, Elnaggar A, Lee SJ, Merek S, Hoffmann TJ, Von Oppenfeld J, Ignacio N, Whooley MA -
Prediabetes-A Risk Factor Twice Removed.
JAMA internal medicine 2021 Lam K, Lee SJ -
A Novel Method for Identifying a Parsimonious and Accurate Predictive Model for Multiple Clinical Outcomes.
Computer methods and programs in biomedicine 2021 Diaz-Ramirez LG, Lee SJ, Smith AK, Gan S, Boscardin WJ -
Preoperative Medical Testing and Falls in Medicare Beneficiaries Awaiting Cataract Surgery.
Ophthalmology 2020 Chen CL, McLeod SD, Lietman TM, Shen H, Boscardin WJ, Chang HP, Whooley MA, Gelb AW, Lee SJ, Dudley RA -
Improving the American Diabetes Association Framework for individualizing treatment in older adults: evaluating life expectancy.
BMJ open diabetes research & care 2020 Lee AK, Steinman MA, Lee SJ -
Integration of an Objective Cognitive Assessment Into a Prognostic Index for 5-Year Mortality Prediction.
Journal of the American Geriatrics Society 2020 Kotwal AA, Lee SJ, Dale W, Boscardin WJ, Waite LJ, Smith AK -
Patients' Use of Social Media for Diabetes Self-Care: Systematic Review.
Journal of medical Internet research 2020 Elnaggar A, Ta Park V, Lee SJ, Bender M, Siegmund LA, Park LG -
Glycemic Over- and Undertreatment in VA Nursing Home Residents with Type 2 Diabetes: a Retrospective Cohort Study.
Journal of general internal medicine 2019 Lederle L, Jing B, Rodriguez A, Hunt LJ, Lee SJ -
Development and Validation of eRADAR: A Tool Using EHR Data to Detect Unrecognized Dementia.
Journal of the American Geriatrics Society 2019 Barnes DE, Zhou J, Walker RL, Larson EB, Lee SJ, Boscardin WJ, Marcum ZA, Dublin S -
Prognostic value of a rapid sarcopenia measure in acutely ill older adults.
Clinical nutrition (Edinburgh, Scotland) 2019 Aliberti MJR, Szlejf C, Covinsky KE, Lee SJ, Jacob-Filho W, Suemoto CK -
Palliative Care Needs in Oncology, Cardiology, and Neurology Clinic Patients in the USA.
Journal of general internal medicine 2019 Dudley N, Ritchie CS, Stijacic-Cenzer I, Lee SJ -
Are We Choosing Wisely? Older Adults' Cancer Screening Intentions and Recalled Discussions with Physicians About Stopping.
Journal of general internal medicine 2019 Kotwal AA, Walter LC, Lee SJ, Dale W -
The Quality of Family Relationships, Diabetes Self-Care, and Health Outcomes in Older Adults.
Diabetes spectrum : a publication of the American Diabetes Association 2019 David D, Dalton J, Magny-Normilus C, Brain MM, Linster T, Lee SJ -
"They Don't Trust Us": The Influence of Perceptions of Inadequate Nursing Home Care on Emergency Department Transfers and the Potential Role for Telehealth.
Clinical nursing research 2019 Stephens CE, Halifax E, David D, Bui N, Lee SJ, Shim J, Ritchie CS -
Frailty and mortality: 'Same-same but Different'.
BMJ quality & safety 2019 Lee SJ -
Making Function Part of the Conversation: Clinician Perspectives on Measuring Functional Status in Primary Care.
Journal of the American Geriatrics Society 2018 Nicosia FM, Spar MJ, Steinman MA, Lee SJ, Brown RT -
Prevalence of Multimorbidity Among Older Adults With Advanced Illness Visits to U.S. Subspecialty Clinics.
Journal of pain and symptom management 2018 Dudley N, Lee SJ, Stijacic-Cenzer I, Ritchie CS -
A Cohort Study of Healthcare Utilization in Older Adults with Undiagnosed Dementia.
Journal of general internal medicine 2018 Lee SJ, Larson EB, Dublin S, Walker R, Marcum Z, Barnes D -
Palliative Care Eligibility, Symptom Burden, and Quality-of-Life Ratings in Nursing Home Residents.
JAMA internal medicine 2018 Stephens CE, Hunt LJ, Bui N, Halifax E, Ritchie CS, Lee SJ -
Individualizing Prevention for Older Adults.
Journal of the American Geriatrics Society 2017 Lee SJ, Kim CM -
Functional Impairment and Decline in Middle Age: A Cohort Study.
Annals of internal medicine 2017 Brown RT, Diaz-Ramirez LG, Boscardin WJ, Lee SJ, Steinman MA -
Glycemic Control and Functionality in Nursing Homes-More Than HbA1c-Reply.
JAMA internal medicine 2017 Lee SJ -
Association of β-Blockers With Functional Outcomes, Death, and Rehospitalization in Older Nursing Home Residents After Acute Myocardial Infarction.
JAMA internal medicine 2017 Steinman MA, Zullo AR, Lee Y, Daiello LA, Boscardin WJ, Dore DD, Gan S, Fung K, Lee SJ, Komaiko KD, Mor V -
Changes in Social Function as a Trigger to Screen for Cognitive Impairment.
Journal of general internal medicine 2016 Romo RD, Lee SJ -
"Everyone else gets ice cream here more often than I do--It burns me up"--Perspectives on Diabetes Care from Nursing Home Residents and their Doctors.
BMC geriatrics 2016 Barnhart C, McClymont K, Smith AK, Au-Yeung A, Lee SJ -
Subjective, Objective, and Observed Long-term Survival: A Longitudinal Cohort Study.
JAMA internal medicine 2015 Romo RD, Lee SJ, Miao Y, Boscardin WJ, Smith AK -
Provider Perspectives on the Influence of Family on Nursing Home Resident Transfers to the Emergency Department: Crises at the End of Life.
Current gerontology and geriatrics research 2015 Stephens C, Halifax E, Bui N, Lee SJ, Harrington C, Shim J, Ritchie C -
Changing Patterns of Glucose-Lowering Medication Use in VA Nursing Home Residents With Diabetes, 2005 to 2011.
Journal of the American Medical Directors Association 2015 Lee SJ, Stijacic-Cenzer I, Barnhart C, McClymont K, Steinman MA -
Time to benefit for colorectal cancer screening: survival meta-analysis of flexible sigmoidoscopy trials.
BMJ (Clinical research ed.) 2015 Tang V, Boscardin WJ, Stijacic-Cenzer I, Lee SJ -
Improving Diabetes Care for Hospice Patients.
The American journal of hospice & palliative care 2015 Lee SJ, Jacobson MA, Johnston CB -
Journalists, district attorneys and researchers: why IRBs should get in the middle.
BMC medical ethics 2015 Chodos AH, Lee SJ -
The burden of nocturia among middle-aged and older women.
Obstetrics and gynecology 2015 Hsu A, Nakagawa S, Walter LC, Van Den Eeden SK, Brown JS, Thom DH, Lee SJ, Huang AJ -
Predictors of urinary incontinence in community-dwelling frail older adults with diabetes mellitus in a cross-sectional study.
BMC geriatrics 2014 Hsu A, Conell-Price J, Stijacic Cenzer I, Eng C, Huang AJ, Rice-Trumble K, Lee SJ -
A clinical index to predict progression from mild cognitive impairment to dementia due to Alzheimer's disease.
PloS one 2014 Lee SJ, Ritchie CS, Yaffe K, Stijacic Cenzer I, Barnes DE -
Usefulness and effect of online prognostic calculators.
Journal of the American Geriatrics Society 2014 McClymont KM, Lee SJ, Schonberg MA, Widera E, Miao Y, Smith AK -
Individualizing life expectancy estimates for older adults using the Gompertz Law of Human Mortality.
PloS one 2014 Lee SJ, Boscardin WJ, Kirby KA, Covinsky KE -
So much insulin, so much hypoglycemia.
JAMA internal medicine 2014 Lee SJ -
Lag time to benefit for preventive therapies--reply.
JAMA 2014 Lee SJ, Leipzig RM, Walter LC -
Emergency department visits and hospitalizations by tube-fed nursing home residents with varying degrees of cognitive impairment: a national study.
BMC geriatrics 2014 Stephens CE, Sackett N, Govindarajan P, Lee SJ -
A point-based tool to predict conversion from mild cognitive impairment to probable Alzheimer's disease.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2014 Barnes DE, Cenzer IS, Yaffe K, Ritchie CS, Lee SJ, Alzheimer's Disease Neuroimaging Initiative -
Incorporating lag time to benefit into prevention decisions for older adults.
JAMA 2013 Lee SJ, Leipzig RM, Walter LC -
Glycemic control and urinary incontinence in women with diabetes mellitus.
Journal of women's health (2002) 2013 Lee SJ, Karter AJ, Thai JN, Van Den Eeden SK, Huang ES -
Transitional care challenges of rehospitalized veterans: listening to patients and providers.
Population health management 2013 Stephens C, Sackett N, Pierce R, Schopfer D, Schmajuk G, Moy N, Bachhuber M, Wallhagen MI, Lee SJ -
Predicting 10-year mortality for older adults.
JAMA 2013 Cruz M, Covinsky K, Widera EW, Stijacic-Cenzer I, Lee SJ -
Time lag to benefit after screening for breast and colorectal cancer: meta-analysis of survival data from the United States, Sweden, United Kingdom, and Denmark.
BMJ (Clinical research ed.) 2013 Lee SJ, Boscardin WJ, Stijacic-Cenzer I, Conell-Price J, O'Brien S, Walter LC -
Patterns of multimorbidity in elderly veterans.
Journal of the American Geriatrics Society 2012 Steinman MA, Lee SJ, John Boscardin W, Miao Y, Fung KZ, Moore KL, Schwartz JB -
Glycosylated hemoglobin and functional decline in community-dwelling nursing home-eligible elderly adults with diabetes mellitus.
Journal of the American Geriatrics Society 2012 Yau CK, Eng C, Cenzer IS, Boscardin WJ, Rice-Trumble K, Lee SJ -
A clinically guided approach for improving performance measurement for hypertension.
Medical care 2012 Steinman MA, Lee SJ, Peterson CA, Fung KZ, Goldstein MK -
Prognostic indices for older adults: a systematic review.
JAMA 2012 Yourman LC, Lee SJ, Schonberg MA, Widera EW, Smith AK -
Predicting Alzheimer's risk: why and how?
Alzheimer's research & therapy 2011 Barnes DE, Lee SJ -
Quality indicators for older adults: preventing unintended harms.
JAMA 2011 Lee SJ, Walter LC -
The risks and benefits of implementing glycemic control guidelines in frail older adults with diabetes mellitus.
Journal of the American Geriatrics Society 2011 Lee SJ, Boscardin WJ, Stijacic Cenzer I, Huang ES, Rice-Trumble K, Eng C -
Goals of glycemic control in frail older patients with diabetes.
JAMA 2011 Lee SJ, Eng C -
Volunteering, driving status, and mortality in U.S. retirees.
Journal of the American Geriatrics Society 2011 Lee SJ, Steinman MA, Tan EJ -
Coming home: health status and homelessness risk of older pre-release prisoners.
Journal of general internal medicine 2010 Williams BA, McGuire J, Lindsay RG, Baillargeon J, Cenzer IS, Lee SJ, Kushel M -
Missed opportunities for osteoporosis treatment in patients hospitalized for hip fracture.
Journal of the American Geriatrics Society 2010 Jennings LA, Auerbach AD, Maselli J, Pekow PS, Lindenauer PK, Lee SJ -
The Department of Veterans Affairs National Quality Scholars Fellowship Program: experience from 10 years of training quality scholars.
Academic medicine : journal of the Association of American Medical Colleges 2009 Splaine ME, Ogrinc G, Gilman SC, Aron DC, Estrada CA, Rosenthal GE, Lee S, Dittus RS, Batalden PB -
Impact of age and comorbidity on colorectal cancer screening among older veterans.
Annals of internal medicine 2009 Walter LC, Lindquist K, Nugent S, Schult T, Lee SJ, Casadei MA, Partin MR -
Association between hospital-reported Leapfrog Safe Practices Scores and inpatient mortality.
JAMA 2009 Kernisan LP, Lee SJ, Boscardin WJ, Landefeld CS, Dudley RA -
Functional limitations, socioeconomic status, and all-cause mortality in moderate alcohol drinkers.
Journal of the American Geriatrics Society 2009 Lee SJ, Sudore RL, Williams BA, Lindquist K, Chen HL, Covinsky KE -
Chronic conditions and mortality among the oldest old.
American journal of public health 2008 Lee SJ, Go AS, Lindquist K, Bertenthal D, Covinsky KE -
The relationship between self-rated health and mortality in older black and white Americans.
Journal of the American Geriatrics Society 2007 Lee SJ, Moody-Ayers SY, Landefeld CS, Walter LC, Lindquist K, Segal MR, Covinsky KE -
Development and validation of a prognostic index for 4-year mortality in older adults.
JAMA 2006 Lee SJ, Lindquist K, Segal MR, Covinsky KE