Scott Vandenberg, MD, PhD
Professor
Pathology
School of Medicine

Education & Training

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• Ph.D. Bio & Behavioral Neurosciences Stanford University 1979
• M.D. Medicine Stanford University 1979
• B.S. Zoology Duke University 1972

Grants and Projects

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• A shared resource for multiplexed ion beam imaging microscopy, NIH, 2018-2020
• Neuropathology Research, NIH, 1983-1993
• Monoamines in Embryonal Cns Tumor Differentiation, NIH, 1986-1990
• Monoamines in Embryonal Cns Tumor Differentiation, NIH, 1984-1989

Publications (163)

Top publication keywords:
EpendymomaAstrocytesAnnexin A2Receptors, LDLGlioblastomaDacarbazineReceptors, Urokinase Plasminogen ActivatorMitogen-Activated Protein KinasesErbB ReceptorsAstrocytomaGene Expression Regulation, NeoplasticBrain NeoplasmsTeratomaGliomaOligodendroglioma

• Multi-platform biomarkers of response to an immune checkpoint inhibitor in the neoadjuvant I-SPY 2 trial for early-stage breast cancer.
  Cell reports. Medicine 2024 Campbell MJ, Wolf DM, Yau C, Brown-Swigart L, Wulfkuhle J, Gallagher IR, Zhu Z, Bolen J, Vandenberg S, Hoyt C, Mori H, Borowsky A, Sit L, Perlmutter J, Asare SM, I-SPY2 Investigators, Nanda R, Liu MC,…
• A reversible SRC-relayed COX2 inflammatory program drives resistance to BRAF and EGFR inhibition in BRAFV600E colorectal tumors.
  Nature cancer 2023 Ruiz-Saenz A, Atreya CE, Wang C, Pan B, Dreyer CA, Brunen D, Prahallad A, Muñoz DP, Ramms DJ, Burghi V, Spassov DS, Fewings E, Hwang YC, Cowdrey C, Moelders C, Schwarzer C, Wolf DM, Hann B, VandenBerg…
• The surfaceome of multiple myeloma cells suggests potential immunotherapeutic strategies and protein markers of drug resistance.
  Nature communications 2022 Ferguson ID, Patiño-Escobar B, Tuomivaara ST, Lin YT, Nix MA, Leung KK, Kasap C, Ramos E, Nieves Vasquez W, Talbot A, Hale M, Naik A, Kishishita A, Choudhry P, Lopez-Girona A, Miao W, Wong SW, Wolf JL…
• Caveolin-1 and Sox-2 are predictive biomarkers of cetuximab response in head and neck cancer.
  JCI insight 2021 Bouhaddou M, Lee RH, Li H, Bhola NE, O'Keefe RA, Naser M, Zhu TR, Nwachuku K, Duvvuri U, Olshen AB, Roy R, Hechmer A, Bolen J, Keysar SB, Jimeno A, Mills GB, Vandenberg S, Swaney DL, Johnson DE, …
• Genetically edited CD34+ cells derived from human iPS cells in vivo but not in vitro engraft and differentiate into HIV-resistant cells.
  Proceedings of the National Academy of Sciences of the United States of America 2021 Morvan MG, Teque F, Ye L, Moreno ME, Wang J, VandenBerg S, Stoddart CA, Kan YW, Levy JA

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• Characterizing the Tumor Immune Microenvironment with Tyramide-Based Multiplex Immunofluorescence.
  Journal of mammary gland biology and neoplasia 2021 Mori H, Bolen J, Schuetter L, Massion P, Hoyt CC, VandenBerg S, Esserman L, Borowsky AD, Campbell MJ
• A multi-modal data resource for investigating topographic heterogeneity in patient-derived xenograft tumors.
  Scientific data 2019 Rajaram S, Roth MA, Malato J, VandenBerg S, Hann B, Atreya CE, Altschuler SJ, Wu LF
• Myc and Loss of p53 Cooperate to Drive Formation of Choroid Plexus Carcinoma.
  Cancer research 2019 Wang J, Merino DM, Light N, Murphy BL, Wang YD, Guo X, Hodges AP, Chau LQ, Liu KW, Dhall G, Asgharzadeh S, Kiehna EN, Shirey RJ, Janda KD, Taylor MD, Malkin D, Ellison DW, VandenBerg SR, Eberhart CG, …
• Use of nonsteroidal anti-inflammatory drugs predicts improved patient survival for PIK3CA-altered head and neck cancer.
  The Journal of experimental medicine 2019 Hedberg ML, Peyser ND, Bauman JE, Gooding WE, Li H, Bhola NE, Zhu TR, Zeng Y, Brand TM, Kim MO, Jordan RCK, VandenBerg S, Olivas V, Bivona TG, Chiosea SI, Wang L, Mills GB, Johnson JT, Duvvuri U, …
• mTOR activity in AIDS-related diffuse large B-cell lymphoma.
  PloS one 2017 Browne SH, Diaz-Perez JA, Preziosi M, King CC, Jones GA, Jain S, Sun X, Reid EG, VandenBerg S, Wang HY
• Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity.
  Nature 2017 Turner KM, Deshpande V, Beyter D, Koga T, Rusert J, Lee C, Li B, Arden K, Ren B, Nathanson DA, Kornblum HI, Taylor MD, Kaushal S, Cavenee WK, Wechsler-Reya R, Furnari FB, Vandenberg SR, Rao PN, Wahl …
• Assessing Researcher Needs for a Virtual Biobank.
  Biopreservation and biobanking 2016 van Draanen J, Davidson P, Bour-Jordan H, Bowman-Carpio L, Boyle D, Dubinett S, Gardner B, Gardner J, McFall C, Mercola D, Nakazono T, Soares S, Stoppler H, Tempero M, Vandenberg S, Wan YJ, Dry S
• Magnetic resonance imaging of myelin using ultrashort Echo time (UTE) pulse sequences: Phantom, specimen, volunteer and multiple sclerosis patient studies.
  NeuroImage 2016 Sheth V, Shao H, Chen J, Vandenberg S, Corey-Bloom J, Bydder GM, Du J
• A 22-Year Old Woman with Right Eyelid Swelling.
  Brain pathology (Zurich, Switzerland) 2016 van Vugt VA, Kesari A, Muller KA, Carter B, Vandenberg SR, Kesari S
• Selective coexpression of VEGF receptor 2 in EGFRvIII-positive glioblastoma cells prevents cellular senescence and contributes to their aggressive nature.
  Neuro-oncology 2015 Jones KA, Gilder AS, Lam MS, Du N, Banki MA, Merati A, Pizzo DP, VandenBerg SR, Gonias SL
• Pro-angiogenic cellular and genomic expression patterns within glioblastoma influences dynamic susceptibility weighted perfusion MRI.
  Clinical radiology 2015 Barajas RF, Phillips JJ, Vandenberg SR, McDermott MW, Berger MS, Dillon WP, Cha S
• Dynamic epigenetic regulation of glioblastoma tumorigenicity through LSD1 modulation of MYC expression.
  Proceedings of the National Academy of Sciences of the United States of America 2015 Kozono D, Li J, Nitta M, Sampetrean O, Gonda D, Kushwaha DS, Merzon D, Ramakrishnan V, Zhu S, Zhu K, Matsui H, Harismendy O, Hua W, Mao Y, Kwon CH, Saya H, Nakano I, Pizzo DP, VandenBerg SR, Chen CC
• Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.
  The New England journal of medicine 2015 Cancer Genome Atlas Research Network, Brat DJ, Verhaak RG, Aldape KD, Yung WK, Salama SR, Cooper LA, Rheinbay E, Miller CR, Vitucci M, Morozova O, Robertson AG, Noushmehr H, Laird PW, Cherniack AD, …
• A urokinase receptor-Bim signaling axis emerges during EGFR inhibitor resistance in mutant EGFR glioblastoma.
  Cancer research 2014 Wykosky J, Hu J, Gomez GG, Taylor T, Villa GR, Pizzo D, VandenBerg SR, Thorne AH, Chen CC, Mischel PS, Gonias SL, Cavenee WK, Furnari FB
• Neutralizing the EGF receptor in glioblastoma cells stimulates cell migration by activating uPAR-initiated cell signaling.
  Oncogene 2014 Hu J, Muller KA, Furnari FB, Cavenee WK, VandenBerg SR, Gonias SL
• Epigenetic suppression of EGFR signaling in G-CIMP+ glioblastomas.
  Oncotarget 2014 Li J, Taich ZJ, Goyal A, Gonda D, Akers J, Adhikari B, Patel K, Vandenberg S, Yan W, Bao Z, Carter BS, Wang R, Mao Y, Jiang T, Chen CC
• Combining diffusion and perfusion differentiates tumor from bevacizumab-related imaging abnormality (bria).
  Journal of neuro-oncology 2014 Farid N, Almeida-Freitas DB, White NS, McDonald CR, Kuperman JM, Almutairi AA, Muller KA, VandenBerg SR, Kesari S, Dale AM
• Pediatric phase II trials of poly-ICLC in the management of newly diagnosed and recurrent brain tumors.
  Journal of pediatric hematology/oncology 2014 Hartman LL, Crawford JR, Makale MT, Milburn M, Joshi S, Salazar AM, Hasenauer B, VandenBerg SR, MacDonald TJ, Durden DL
• Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma.
  Nature 2014 Northcott PA, Lee C, Zichner T, Stütz AM, Erkek S, Kawauchi D, Shih DJ, Hovestadt V, Zapatka M, Sturm D, Jones DT, Kool M, Remke M, Cavalli FM, Zuyderduyn S, Bader GD, VandenBerg S, Esparza LA, …
• 72 year old female with leg weakness.
  Brain pathology (Zurich, Switzerland) 2014 Mahta A, Borys E, Vandenberg SR, Carter B, Kesari S
• Ultrashort echo time (UTE) magnetic resonance imaging of the short T2 components in white matter of the brain using a clinical 3T scanner.
  NeuroImage 2013 Du J, Ma G, Li S, Carl M, Szeverenyi NM, VandenBerg S, Corey-Bloom J, Bydder GM
• 78 year old male with dysphagia and dysarthria.
  Brain pathology (Zurich, Switzerland) 2013 Mahta A, Du Z, Borys E, Carter B, Vandenberg SR, Kesari S
• Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration.
  Proceedings of the National Academy of Sciences of the United States of America 2013 Lagier-Tourenne C, Baughn M, Rigo F, Sun S, Liu P, Li HR, Jiang J, Watt AT, Chun S, Katz M, Qiu J, Sun Y, Ling SC, Zhu Q, Polymenidou M, Drenner K, Artates JW, McAlonis-Downes M, Markmiller S, Hutt KR…
• Restriction-Spectrum Imaging of Bevacizumab-Related Necrosis in a Patient with GBM.
  Frontiers in oncology 2013 Farid N, Almeida-Freitas DB, White NS, McDonald CR, Muller KA, Vandenberg SR, Kesari S, Dale AM
• PI3Kα activates integrin α4β1 to establish a metastatic niche in lymph nodes.
  Proceedings of the National Academy of Sciences of the United States of America 2013 Garmy-Susini B, Avraamides CJ, Desgrosellier JS, Schmid MC, Foubert P, Ellies LG, Lowy AM, Blair SL, Vandenberg SR, Datnow B, Wang HY, Cheresh DA, Varner J
• Myeloid cell receptor LRP1/CD91 regulates monocyte recruitment and angiogenesis in tumors.
  Cancer research 2013 Staudt ND, Jo M, Hu J, Bristow JM, Pizzo DP, Gaultier A, VandenBerg SR, Gonias SL
• Loss of acinar cell IKKα triggers spontaneous pancreatitis in mice.
  The Journal of clinical investigation 2013 Li N, Wu X, Holzer RG, Lee JH, Todoric J, Park EJ, Ogata H, Gukovskaya AS, Gukovsky I, Pizzo DP, VandenBerg S, Tarin D, Atay C, Arkan MC, Deerinck TJ, Moscat J, Diaz-Meco M, Dawson D, Erkan M, Kleeff …
• A kinome-wide RNAi screen in Drosophila Glia reveals that the RIO kinases mediate cell proliferation and survival through TORC2-Akt signaling in glioblastoma.
  PLoS genetics 2013 Read RD, Fenton TR, Gomez GG, Wykosky J, Vandenberg SR, Babic I, Iwanami A, Yang H, Cavenee WK, Mischel PS, Furnari FB, Thomas JB
• Role of connexins in metastatic breast cancer and melanoma brain colonization.
  Journal of cell science 2013 Stoletov K, Strnadel J, Zardouzian E, Momiyama M, Park FD, Kelber JA, Pizzo DP, Hoffman R, VandenBerg SR, Klemke RL
• Expression of miR-124 inhibits growth of medulloblastoma cells.
  Neuro-oncology 2012 Silber J, Hashizume R, Felix T, Hariono S, Yu M, Berger MS, Huse JT, VandenBerg SR, James CD, Hodgson JG, Gupta N
• Recurrent pediatric central nervous system low-grade gliomas: the role of surveillance neuroimaging in asymptomatic children.
  Journal of neurosurgery. Pediatrics 2012 Udaka YT, Yeh-Nayre LA, Amene CS, VandenBerg SR, Levy ML, Crawford JR
• Resistance to EGF receptor inhibitors in glioblastoma mediated by phosphorylation of the PTEN tumor suppressor at tyrosine 240.
  Proceedings of the National Academy of Sciences of the United States of America 2012 Fenton TR, Nathanson D, Ponte de Albuquerque C, Kuga D, Iwanami A, Dang J, Yang H, Tanaka K, Oba-Shinjo SM, Uno M, Inda MM, Wykosky J, Bachoo RM, James CD, DePinho RA, Vandenberg SR, Zhou H, Marie SK,…
• EGFRvIII promotes glioma angiogenesis and growth through the NF-κB, interleukin-8 pathway.
  Oncogene 2011 Bonavia R, Inda MM, Vandenberg S, Cheng SY, Nagane M, Hadwiger P, Tan P, Sah DW, Cavenee WK, Furnari FB
• Glioblastoma-derived epidermal growth factor receptor carboxyl-terminal deletion mutants are transforming and are sensitive to EGFR-directed therapies.
  Cancer research 2011 Cho J, Pastorino S, Zeng Q, Xu X, Johnson W, Vandenberg S, Verhaak R, Cherniack AD, Watanabe H, Dutt A, Kwon J, Chao YS, Onofrio RC, Chiang D, Yuza Y, Kesari S, Meyerson M
• Asymmetry-defective oligodendrocyte progenitors are glioma precursors.
  Cancer cell 2011 Sugiarto S, Persson AI, Munoz EG, Waldhuber M, Lamagna C, Andor N, Hanecker P, Ayers-Ringler J, Phillips J, Siu J, Lim DA, Vandenberg S, Stallcup W, Berger MS, Bergers G, Weiss WA, Petritsch C
• Crosstalk between the urokinase-type plasminogen activator receptor and EGF receptor variant III supports survival and growth of glioblastoma cells.
  Proceedings of the National Academy of Sciences of the United States of America 2011 Hu J, Jo M, Cavenee WK, Furnari F, VandenBerg SR, Gonias SL
• Phase II and pharmacogenomics study of enzastaurin plus temozolomide during and following radiation therapy in patients with newly diagnosed glioblastoma multiforme and gliosarcoma.
  Neuro-oncology 2011 Butowski N, Chang SM, Lamborn KR, Polley MY, Pieper R, Costello JF, Vandenberg S, Parvataneni R, Nicole A, Sneed PK, Clarke J, Hsieh E, Costa BM, Reis RM, Hristova-Kazmierski M, Nicol SJ, Thornton DE,…
• MRI apparent diffusion coefficient reflects histopathologic subtype, axonal disruption, and tumor fraction in diffuse-type grade II gliomas.
  Neuro-oncology 2011 Khayal IS, Vandenberg SR, Smith KJ, Cloyd CP, Chang SM, Cha S, Nelson SJ, McKnight TR
• DNA hypermethylation profiles associated with glioma subtypes and EZH2 and IGFBP2 mRNA expression.
  Neuro-oncology 2011 Zheng S, Houseman EA, Morrison Z, Wrensch MR, Patoka JS, Ramos C, Haas-Kogan DA, McBride S, Marsit CJ, Christensen BC, Nelson HH, Stokoe D, Wiemels JL, Chang SM, Prados MD, Tihan T, Vandenberg SR, …
• Dose-dependent effects of focal fractionated irradiation on secondary malignant neoplasms in Nf1 mutant mice.
  Cancer research 2011 Nakamura JL, Phong C, Pinarbasi E, Kogan SC, Vandenberg S, Horvai AE, Faddegon BA, Fiedler D, Shokat K, Houseman BT, Chao R, Pieper RO, Shannon K
• OLIG2 is differentially expressed in pediatric astrocytic and in ependymal neoplasms.
  Journal of neuro-oncology 2010 Otero JJ, Rowitch D, Vandenberg S
• The genetic landscape of the childhood cancer medulloblastoma.
  Science (New York, N.Y.) 2010 Parsons DW, Li M, Zhang X, Jones S, Leary RJ, Lin JC, Boca SM, Carter H, Samayoa J, Bettegowda C, Gallia GL, Jallo GI, Binder ZA, Nikolsky Y, Hartigan J, Smith DR, Gerhard DS, Fults DW, VandenBerg S, …
• Non-stem cell origin for oligodendroglioma.
  Cancer cell 2010 Persson AI, Petritsch C, Swartling FJ, Itsara M, Sim FJ, Auvergne R, Goldenberg DD, Vandenberg SR, Nguyen KN, Yakovenko S, Ayers-Ringler J, Nishiyama A, Stallcup WB, Berger MS, Bergers G, McKnight TR,…
• Blocking the mitochondrial apoptotic pathway preserves motor neuron viability and function in a mouse model of amyotrophic lateral sclerosis.
  The Journal of clinical investigation 2010 Reyes NA, Fisher JK, Austgen K, VandenBerg S, Huang EJ, Oakes SA
• Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma.
  Genes & development 2010 Inda MM, Bonavia R, Mukasa A, Narita Y, Sah DW, Vandenberg S, Brennan C, Johns TG, Bachoo R, Hadwiger P, Tan P, Depinho RA, Cavenee W, Furnari F
• Ex vivo MR spectroscopic measure differentiates tumor from treatment effects in GBM.
  Neuro-oncology 2010 Srinivasan R, Phillips JJ, Vandenberg SR, Polley MY, Bourne G, Au A, Pirzkall A, Cha S, Chang SM, Nelson SJ
• Imaging utilization during explosive multiple casualty incidents.
  The Journal of trauma 2010 Raja AS, Propper BW, Vandenberg SL, Matchette MW, Rasmussen TE, Johannigman JA, Davidson SB
• Pleiotropic role for MYCN in medulloblastoma.
  Genes & development 2010 Swartling FJ, Grimmer MR, Hackett CS, Northcott PA, Fan QW, Goldenberg DD, Lau J, Masic S, Nguyen K, Yakovenko S, Zhe XN, Gilmer HC, Collins R, Nagaoka M, Phillips JJ, Jenkins RB, Tihan T, Vandenberg …
• Gene expression profiles help identify the tissue of origin for metastatic brain cancers.
  Diagnostic pathology 2010 Wu AH, Drees JC, Wang H, VandenBerg SR, Lal A, Henner WD, Pillai R
• A hierarchy of self-renewing tumor-initiating cell types in glioblastoma.
  Cancer cell 2010 Chen R, Nishimura MC, Bumbaca SM, Kharbanda S, Forrest WF, Kasman IM, Greve JM, Soriano RH, Gilmour LL, Rivers CS, Modrusan Z, Nacu S, Guerrero S, Edgar KA, Wallin JJ, Lamszus K, Westphal M, Heim S, …
• Glioblastoma multiforme regional genetic and cellular expression patterns: influence on anatomic and physiologic MR imaging.
  Radiology 2010 Barajas RF, Hodgson JG, Chang JS, Vandenberg SR, Yeh RF, Parsa AT, McDermott MW, Berger MS, Dillon WP, Cha S
• Hyperpolarized 13C magnetic resonance metabolic imaging: application to brain tumors.
  Neuro-oncology 2010 Park I, Larson PE, Zierhut ML, Hu S, Bok R, Ozawa T, Kurhanewicz J, Vigneron DB, Vandenberg SR, James CD, Nelson SJ
• Oncogenic BRAF mutation with CDKN2A inactivation is characteristic of a subset of pediatric malignant astrocytomas.
  Cancer research 2010 Schiffman JD, Hodgson JG, VandenBerg SR, Flaherty P, Polley MY, Yu M, Fisher PG, Rowitch DH, Ford JM, Berger MS, Ji H, Gutmann DH, James CD
• Morphologic and molecular characterization of ATRT xenografts adapted for orthotopic therapeutic testing.
  Neuro-oncology 2010 Hashizume R, Gupta N, Berger MS, Banerjee A, Prados MD, Ayers-Ringler J, James CD, VandenBerg SR
• Multiparametric characterization of grade 2 glioma subtypes using magnetic resonance spectroscopic, perfusion, and diffusion imaging.
  Translational oncology 2009 Bian W, Khayal IS, Lupo JM, McGue C, Vandenberg S, Lamborn KR, Chang SM, Cha S, Nelson SJ
• Tumor regrowth between surgery and initiation of adjuvant therapy in patients with newly diagnosed glioblastoma.
  Neuro-oncology 2009 Pirzkall A, McGue C, Saraswathy S, Cha S, Liu R, Vandenberg S, Lamborn KR, Berger MS, Chang SM, Nelson SJ
• Post-radiation reactive changes in a single vertebral body mimicking metastatic pineoblastoma.
  Journal of neurosurgery. Pediatrics 2009 Tate MC, Banerjee A, Vandenberg SR, Tihan T, Chi JH, Ames CP, Parsa AT
• Activation of PI3K/mTOR pathway occurs in most adult low-grade gliomas and predicts patient survival.
  Journal of neuro-oncology 2009 McBride SM, Perez DA, Polley MY, Vandenberg SR, Smith JS, Zheng S, Lamborn KR, Wiencke JK, Chang SM, Prados MD, Berger MS, Stokoe D, Haas-Kogan DA
• Apparent diffusion coefficient and fractional anisotropy of newly diagnosed grade II gliomas.
  NMR in biomedicine 2009 Khayal IS, McKnight TR, McGue C, Vandenberg S, Lamborn KR, Chang SM, Cha S, Nelson SJ
• Integration of preoperative anatomic and metabolic physiologic imaging of newly diagnosed glioma.
  Journal of neuro-oncology 2009 Chang SM, Nelson S, Vandenberg S, Cha S, Prados M, Butowski N, McDermott M, Parsa AT, Aghi M, Clarke J, Berger M
• Comparative analyses of gene copy number and mRNA expression in glioblastoma multiforme tumors and xenografts.
  Neuro-oncology 2009 Hodgson JG, Yeh RF, Ray A, Wang NJ, Smirnov I, Yu M, Hariono S, Silber J, Feiler HS, Gray JW, Spellman PT, Vandenberg SR, Berger MS, James CD
• Phase II study of erlotinib plus temozolomide during and after radiation therapy in patients with newly diagnosed glioblastoma multiforme or gliosarcoma.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008 Prados MD, Chang SM, Butowski N, DeBoer R, Parvataneni R, Carliner H, Kabuubi P, Ayers-Ringler J, Rabbitt J, Page M, Fedoroff A, Sneed PK, Berger MS, McDermott MW, Parsa AT, Vandenberg S, James CD, …
• p53 Small-molecule inhibitor enhances temozolomide cytotoxic activity against intracranial glioblastoma xenografts.
  Cancer research 2008 Dinca EB, Lu KV, Sarkaria JN, Pieper RO, Prados MD, Haas-Kogan DA, Vandenberg SR, Berger MS, James CD
• The neurofibromatosis 2 tumor suppressor gene product, merlin, regulates human meningioma cell growth by signaling through YAP.
  Neoplasia (New York, N.Y.) 2008 Striedinger K, VandenBerg SR, Baia GS, McDermott MW, Gutmann DH, Lal A
• The 2007 WHO classification of tumors of the nervous system: controversies in surgical neuropathology.
  Brain pathology (Zurich, Switzerland) 2008 Scheithauer BW, Fuller GN, VandenBerg SR
• miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells.
  BMC medicine 2008 Silber J, Lim DA, Petritsch C, Persson AI, Maunakea AK, Yu M, Vandenberg SR, Ginzinger DG, James CD, Costello JF, Bergers G, Weiss WA, Alvarez-Buylla A, Hodgson JG
• Matrix metalloproteinase-2 regulates vascular patterning and growth affecting tumor cell survival and invasion in GBM.
  Neuro-oncology 2008 Du R, Petritsch C, Lu K, Liu P, Haller A, Ganss R, Song H, Vandenberg S, Bergers G
• Role of extent of resection in the long-term outcome of low-grade hemispheric gliomas.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008 Smith JS, Chang EF, Lamborn KR, Chang SM, Prados MD, Cha S, Tihan T, Vandenberg S, McDermott MW, Berger MS
• HIF1alpha induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion.
  Cancer cell 2008 Du R, Lu KV, Petritsch C, Liu P, Ganss R, Passegué E, Song H, Vandenberg S, Johnson RS, Werb Z, Bergers G
• Safety of real-time convection-enhanced delivery of liposomes to primate brain: a long-term retrospective.
  Experimental neurology 2007 Krauze MT, Vandenberg SR, Yamashita Y, Saito R, Forsayeth J, Noble C, Park J, Bankiewicz KS
• An orthotopic skull base model of malignant meningioma.
  Brain pathology (Zurich, Switzerland) 2007 Baia GS, Dinca EB, Ozawa T, Kimura ET, McDermott MW, James CD, VandenBerg SR, Lal A
• Molecular signatures define two main classes of meningiomas.
  Molecular cancer 2007 Carvalho LH, Smirnov I, Baia GS, Modrusan Z, Smith JS, Jun P, Costello JF, McDermott MW, Vandenberg SR, Lal A
• Relationship of glioblastoma multiforme to neural stem cell regions predicts invasive and multifocal tumor phenotype.
  Neuro-oncology 2007 Lim DA, Cha S, Mayo MC, Chen MH, Keles E, VandenBerg S, Berger MS
• Methylation of the PTEN promoter defines low-grade gliomas and secondary glioblastoma.
  Neuro-oncology 2007 Wiencke JK, Zheng S, Jelluma N, Tihan T, Vandenberg S, Tamgüney T, Baumber R, Parsons R, Lamborn KR, Berger MS, Wrensch MR, Haas-Kogan DA, Stokoe D
• In vivo efficacy of a novel histone deacetylase inhibitor in combination with radiation for the treatment of gliomas.
  Neuro-oncology 2007 Entin-Meer M, Yang X, VandenBerg SR, Lamborn KR, Nudelman A, Rephaeli A, Haas-Kogan DA
• Expression of the hypoxia marker carbonic anhydrase 9 is associated with anaplastic phenotypes in meningiomas.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2007 Yoo H, Baia GS, Smith JS, McDermott MW, Bollen AW, Vandenberg SR, Lamborn KR, Lal A
• Genome-wide hypomethylation in human glioblastomas associated with specific copy number alteration, methylenetetrahydrofolate reductase allele status, and increased proliferation.
  Cancer research 2006 Cadieux B, Ching TT, VandenBerg SR, Costello JF
• PDGFR alpha-positive B cells are neural stem cells in the adult SVZ that form glioma-like growths in response to increased PDGF signaling.
  Neuron 2006 Jackson EL, Garcia-Verdugo JM, Gil-Perotin S, Roy M, Quinones-Hinojosa A, VandenBerg S, Alvarez-Buylla A
• A genetic strategy to overcome the senescence of primary meningioma cell cultures.
  Journal of neuro-oncology 2006 Baia GS, Slocum AL, Hyer JD, Misra A, Sehati N, VandenBerg SR, Feuerstein BG, Deen DF, McDermott MW, Lal A
• Butyric acid prodrugs are histone deacetylase inhibitors that show antineoplastic activity and radiosensitizing capacity in the treatment of malignant gliomas.
  Molecular cancer therapeutics 2005 Entin-Meer M, Rephaeli A, Yang X, Nudelman A, VandenBerg SR, Haas-Kogan DA
• Bromophenol blue staining of tumors in a rat glioma model.
  Neurosurgery 2005 Ozawa T, Britz GW, Kinder DH, Spence AM, VandenBerg S, Lamborn KR, Deen DF, Berger MS
• Mitochondrial DNA depletion analysis by pseudogene ratioing.
  Journal of neuroscience methods 2005 Swerdlow RH, Redpath GT, Binder DR, Davis JN, VandenBerg SR
• Comparing the protein expression profiles of human mesenchymal stem cells and human osteoblasts using gene ontologies.
  Stem cells and development 2005 Salasznyk RM, Westcott AM, Klees RF, Ward DF, Xiang Z, Vandenberg S, Bennett K, Plopper GE
• Indicators of hippocampal neurogenesis are altered by 56Fe-particle irradiation in a dose-dependent manner.
  Radiation research 2004 Rola R, Otsuka S, Obenaus A, Nelson GA, Limoli CL, VandenBerg SR, Fike JR
• Radiation-induced impairment of hippocampal neurogenesis is associated with cognitive deficits in young mice.
  Experimental neurology 2004 Rola R, Raber J, Rizk A, Otsuka S, VandenBerg SR, Morhardt DR, Fike JR
• Radiation-induced cognitive impairments are associated with changes in indicators of hippocampal neurogenesis.
  Radiation research 2004 Raber J, Rola R, LeFevour A, Morhardt D, Curley J, Mizumatsu S, VandenBerg SR, Fike JR
• Intracranial metastasis of a primary scalp angiosarcoma. Case illustration.
  Journal of neurosurgery 2002 Ellegala DB, Kligori C, Vandenberg S, Dumont A, Shaffrey ME
• Immunophenotype of pleomorphic xanthoastrocytoma.
  The American journal of surgical pathology 2002 Giannini C, Scheithauer BW, Lopes MB, Hirose T, Kros JM, VandenBerg SR
• Protein kinase C-eta regulates resistance to UV- and gamma-irradiation-induced apoptosis in glioblastoma cells by preventing caspase-9 activation.
  Neuro-oncology 2002 Hussaini IM, Carpenter JE, Redpath GT, Sando JJ, Shaffrey ME, Vandenberg SR
• Control of the nuclear-cytoplasmic partitioning of annexin II by a nuclear export signal and by p11 binding.
  Journal of cell science 2001 Eberhard DA, Karns LR, VandenBerg SR, Creutz CE
• Mechanical trauma induces rapid astroglial activation of ERK/MAP kinase: Evidence for a paracrine signal.
  Glia 2001 Mandell JW, Gocan NC, Vandenberg SR
• Phorbol 12-myristate 13-acetate induces protein kinase ceta-specific proliferative response in astrocytic tumor cells.
  The Journal of biological chemistry 2000 Hussaini IM, Karns LR, Vinton G, Carpenter JE, Redpath GT, Sando JJ, VandenBerg SR
• ERK/MAP kinase is chronically activated in human reactive astrocytes.
  Neuroreport 1999 Mandell JW, VandenBerg SR
• Insulin-like growth factor-1 content and pattern of expression correlates with histopathologic grade in diffusely infiltrating astrocytomas.
  Neuro-oncology 1999 Hirano H, Lopes MB, Laws ER, Asakura T, Goto M, Carpenter JE, Karns LR, VandenBerg SR
• Stable antisense RNA expression neutralizes the activity of low-density lipoprotein receptor-related protein and promotes urokinase accumulation in the medium of an astrocytic tumor cell line.
  Antisense & nucleic acid drug development 1999 Hussaini IM, Brown MD, Weaver AM, Carpenter J, Karns LR, Vandenberg SR, Gonias SL
• Epidermal growth factor differentially regulates low density lipoprotein receptor-related protein gene expression in neoplastic and fetal human astrocytes.
  Glia 1999 Hussaini IM, Brown MD, Karns LR, Carpenter J, Redpath GT, Gonias SL, Vandenberg SR
• In situ visualization of intratumor growth factor signaling: immunohistochemical localization of activated ERK/MAP kinase in glial neoplasms.
  The American journal of pathology 1998 Mandell JW, Hussaini IM, Zecevic M, Weber MJ, VandenBerg SR
• Annexins I and II bind to lipid A: a possible role in the inhibition of endotoxins.
  The Biochemical journal 1998 Eberhard DA, Vandenberg SR
• Quantitative chromatin pattern description in Feulgen-stained nuclei as a diagnostic tool to characterize the oligodendroglial and astroglial components in mixed oligo-astrocytomas.
  Journal of neuropathology and experimental neurology 1997 Decaestecker C, Lopes BS, Gordower L, Camby I, Cras P, Martin JJ, Kiss R, VandenBerg SR, Salmon I
• Ganglioglioma: an ultrastructural and immunohistochemical study.
  Cancer 1997 Hirose T, Scheithauer BW, Lopes MB, Gerber HA, Altermatt HJ, VandenBerg SR
• Low density lipoprotein receptor-related protein is expressed early and becomes restricted to a somatodendritic domain during neuronal differentiation in culture.
  Brain research 1997 Brown MD, Banker GA, Hussaini IM, Gonias SL, VandenBerg SR
• Maturation of intracranial immature teratomas. Report of two cases.
  Journal of neurosurgery 1996 Shaffrey ME, Lanzino G, Lopes MB, Hessler RB, Kassell NF, VandenBerg SR
• Transcriptional regulation of LDL receptor-related protein by IFN-gamma and the antagonistic activity of TGF-beta(1) in the RAW 264.7 macrophage-like cell line.
  Journal of leukocyte biology 1996 Hussaini IM, LaMarre J, Lysiak JJ, Karns LR, VandenBerg SR, Gonias SL
• Immunohistochemical characterization of subependymal giant cell astrocytomas.
  Acta neuropathologica 1996 Lopes MB, Altermatt HJ, Scheithauer BW, Shepherd CW, VandenBerg SR
• Olfactory neuroblastoma. An immunohistochemical, ultrastructural, and flow cytometric study.
  Cancer 1995 Hirose T, Scheithauer BW, Lopes MB, Gerber HA, Altermatt HJ, Harner SG, VandenBerg SR
• Prolonged survival in carcinomatous meningitis associated with breast cancer.
  Southern medical journal 1995 Moots PL, Harrison MB, Vandenberg SR
• Tuber and subependymal giant cell astrocytoma associated with tuberous sclerosis: an immunohistochemical, ultrastructural, and immunoelectron and microscopic study.
  Acta neuropathologica 1995 Hirose T, Scheithauer BW, Lopes MB, Gerber HA, Altermatt HJ, Hukee MJ, VandenBerg SR, Charlesworth JC
• Alterations of annexin expression in pathological neuronal and glial reactions. Immunohistochemical localization of annexins I, II (p36 and p11 subunits), IV, and VI in the human hippocampus.
  The American journal of pathology 1994 Eberhard DA, Brown MD, VandenBerg SR
• Pertussis toxin activates platelets through an interaction with platelet glycoprotein Ib.
  Infection and immunity 1994 Sindt KA, Hewlett EL, Redpath GT, Rappuoli R, Gray LS, Vandenberg SR
• Dysembryoplastic neuroeptihelial tumor (DNT): an immunohistochemical and ultrastructural study.
  Journal of neuropathology and experimental neurology 1994 Hirose T, Scheithauer BW, Lopes MB, VandenBerg SR
• Expression of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein is increased in reactive and neoplastic glial cells.
  FEBS letters 1994 Lopes MB, Bogaev CA, Gonias SL, VandenBerg SR
• Neurenteric cyst or teratomatous cyst.
  Journal of neurosurgery 1994 VandenBerg S
• Plasmin modulates the thrombin-evoked calcium response in C6 glioma cells.
  The Biochemical journal 1994 Turner JS, Redpath GT, Humphries JE, Gonias SL, Vandenberg SR
• Differential expression of retinal proteins in a pineal parenchymal tumor.
  Journal of neuropathology and experimental neurology 1993 Lopes MB, Gonzalez-Fernandez F, Scheithauer BW, VandenBerg SR
• Pallidoluysian atrophy: dystonia and basal ganglia functional anatomy.
  Neurology 1993 Wooten GF, Lopes MB, Harris WO, Reagan TJ, Vandenberg SR
• Desmoplastic infantile ganglioglioma and desmoplastic cerebral astrocytoma of infancy.
  Brain pathology (Zurich, Switzerland) 1993 VandenBerg SR
• Malignant peripheral nerve sheath tumors. A clinicopathologic study of 28 cases.
  Cancer 1993 Wanebo JE, Malik JM, VandenBerg SR, Wanebo HJ, Driesen N, Persing JA
• The role of protein kinase C in the initial events of platelet activation by thrombin assessed with a selective inhibitor.
  Thrombosis research 1993 Geanacopoulos M, Turner J, Bowling KE, Vandenberg SR, Gear AR
• Current diagnostic concepts of astrocytic tumors.
  Journal of neuropathology and experimental neurology 1992 VandenBerg SR
• Cytoskeletal immunohistochemistry of central neurocytomas.
  The American journal of surgical pathology 1992 Hessler RB, Lopes MB, Frankfurter A, Reidy J, VandenBerg SR
• Remote recurrence of craniopharyngioma in the epidural space. Case report.
  Journal of neurosurgery 1992 Malik JM, Cosgrove GR, VandenBerg SR
• Expression of developmentally defined retinal phenotypes in the histogenesis of retinoblastoma.
  The American journal of pathology 1992 Gonzalez-Fernandez F, Lopes MB, Garcia-Fernandez JM, Foster RG, De Grip WJ, Rosemberg S, Newman SA, VandenBerg SR
• Characterization and immunohistochemical localization of alpha 2-macroglobulin receptor (low-density lipoprotein receptor-related protein) in human brain.
  The American journal of pathology 1992 Wolf BB, Lopes MB, VandenBerg SR, Gonias SL
• Elimination of ascorbic acid-induced membrane lipid peroxidation and serotonin receptor loss by Trolox-C, a water soluble analogue of vitamin E.
  Journal of receptor research 1992 Britt SG, Chiu VW, Redpath GT, VandenBerg SR
• Electrophysiological findings in localized hypertrophic mononeuropathy.
  Muscle & nerve 1991 Phillips LH, Persing JA, Vandenberg SR
• The art of brain tumour classification--a tribute to Lucien J. Rubinstein (1925-1990). Interview by Paul Kleihues.
  Brain pathology (Zurich, Switzerland) 1990 Davis RL, Kepes JJ, Rorke LB, VandenBerg SR
• Primary CNS lymphoma: lymphomatous meningitis presenting as a cauda equina lesion in an AIDS patient.
  The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 1990 Klein P, Zientek G, VandenBerg SR, Lothman E
• Secretion of alpha 2-macroglobulin, alpha 2-antiplasmin, and plasminogen activator inhibitor-1 by glioblastoma multiforme in primary organ culture.
  Journal of neurosurgery 1990 Keohane ME, Hall SW, VandenBerg SR, Gonias SL
• Fluoxetine and the bleeding time.
  Archives of pathology & laboratory medicine 1990 Humphries JE, Wheby MS, VandenBerg SR
• Plasminogen carbohydrate side chains in receptor binding and enzyme activation: a study of C6 glioma cells and primary cultures of rat hepatocytes.
  Journal of cellular biochemistry 1990 Hall SW, VandenBerg SR, Gonias SL
• 5-Hydroxytryptamine2 (5-HT2) structure-function relationships of the nitro and amino phenylpiperazines on intact human platelets.
  Biochemical pharmacology 1989 VandenBerg SR, Britt SG, Redpath GT, Gonias SL
• Focal cerebral infarctions associated with perivascular tumor infiltrates in carcinomatous leptomeningeal metastases.
  Archives of neurology 1989 Klein P, Haley EC, Wooten GF, VandenBerg SR
• Expression of plasminogen receptors on C6 glioma cells.
  Brain research 1989 Hall SW, VandenBerg SR, Gonias SL
• Plasminogen binding to rat hepatocytes in primary culture and to thin slices of rat liver.
  Blood 1989 Gonias SL, Braud LL, Geary WA, VandenBerg SR
• Modulatory effects of aluminum, calcium, lithium, magnesium, and zinc ions on [3H]MK-801 binding in human cerebral cortex.
  Brain research 1989 Hubbard CM, Redpath GT, Macdonald TL, VandenBerg SR
• A long-term intravenous model of aluminum maltol toxicity in rabbits: tissue distribution, hepatic, renal, and neuronal cytoskeletal changes associated with systemic exposure.
  Toxicology and applied pharmacology 1989 Bertholf RL, Herman MM, Savory J, Carpenter RM, Sturgill BC, Katsetos CD, Vandenberg SR, Wills MR
• Covalent complexes of albumin with serotonin, ketanserin and lysergic acid antagonize the activity of serotonin in human platelets.
  Life sciences 1989 VandenBerg SR, Gonias SL
• Solid phase extraction of the zwitterionic detergent chaps.
  Preparative biochemistry 1989 Hall SW, VandenBerg SR
• Agonist and antagonist activities of arylpiperazines at human platelet serotonin2 receptors.
  The Journal of pharmacology and experimental therapeutics 1988 Britt SG, Gonias SL, Sanders JM, Vandenberg SR
• The immunohistochemical demonstration of early perineurial change in the development of localized hypertrophic neuropathy.
  Human pathology 1988 Stanton C, Perentes E, Phillips L, VandenBerg SR
• Desmoplastic supratentorial neuroepithelial tumors of infancy with divergent differentiation potential ("desmoplastic infantile gangliogliomas"). Report on 11 cases of a distinctive embryonal tumor with favorable prognosis.
  Journal of neurosurgery 1987 VandenBerg SR, May EE, Rubinstein LJ, Herman MM, Perentes E, Vinores SA, Collins VP, Park TS
• Embryonal central neuroepithelial tumors: current concepts and future challenges.
  Cancer metastasis reviews 1987 Vandenberg SR, Herman MM, Rubinstein LJ
• Long term survival of a patient with an intracranial ependymoma: case report.
  Neurosurgery 1986 Grady MS, Vandenberg SR, Jane JA
• Selective peripancreatic sarcoma metastases from primary gliosarcoma. Case report.
  Journal of neurosurgery 1984 Weaver D, Vandenberg S, Park TS, Jane JA
• Solubilization and characterization of high-affinity [3H]serotonin binding sites from bovine cortical membranes.
  Proceedings of the National Academy of Sciences of the United States of America 1983 VandenBerg SR, Allgren RL, Todd RD, Ciaranello RD
• Immunologic recognition of cell surface antigens in normal mouse neural tissues and in neuroepithelial cells of the OTT-6050 mouse teratoma. A radiometric, gel electrophoretic and morphologic (immunofluorescence and immunoperoxidase) study.
  Acta neuropathologica 1982 Ramsay PB, VandenBerg SR, Eng LF, Herman MM, Rubinstein LJ
• Neural differentiation in the OTT-6050 mouse teratoma. Production of a tumor fraction restricted to stem cells and neural cells after centrifugal elutriation.
  Virchows Archiv. A, Pathological anatomy and histology 1981 VandenBerg SR, Chatel M, Griffiths OM, DeArmond SJ, Pappas C, Herman MM
• Neural differentiation in the OTT-6050 mouse teratoma. Production of a tumor fraction showing melanogenesis in neuroepithelial cells after centrifugal elutriation.
  Virchows Archiv. A, Pathological anatomy and histology 1981 VandenBerg SR, Hess JR, Herman MM, DeArmond SJ, Halks-Miller M, Rubinstein LJ
• Neural differentiation in the OTT-6050 mouse teratoma: effects of intracerebral environment on the neural differentiation of embryoid bodies.
  Virchows Archiv. A, Pathological anatomy and histology 1981 DeArmond SJ, VandenBerg SR, Herman MM
• Neural differentiation in the OTT-6050 mouse teratoma: enzymatic and immunofluorescence characterization of a tumor fraction showing melanogenesis in neuroepithelial cells.
  Virchows Archiv. A, Pathological anatomy and histology 1981 Erdelyi E, VandenBerg SR, Raese J, Barchas JD, Rubinstein LJ, Herman MM
• Non-histone chromosomal proteins in mouse brain at different stages of development and in a transplantable mouse teratoma.
  Journal of neurochemistry 1977 Choie DD, Friedberg EC, VandenBerg SR, Herman MM
• Brain-associated cell surface antigens on neuroepithelial cells in a transplantable mouse teratoma.
  Acta neuropathologica 1977 VandenBerg SR, Hickey JE, Herman MM
• Characterization of two different alkaline phosphatases in mouse teratoma: partial purification, electrophoretic, and histochemical studies.
  Cell 1976 Wada HG, VandenBerg SR, Sussman HH, Grove WE, Herman MM
• In vitro astrocytic differentiation from embryoid bodies of an experimental mouse testicular teratoma.
  The American journal of pathology 1976 VandenBerg SR, Ludwin SK, Herman MM, Bignami A
• Neurochemical studies in a mouse teratoma with neuroepithelial differentiation. Presence of cyclic AMP, serotonin and enzymes of the serotonergic, adrenergic and cholinergic systems.
  Brain research 1976 Orenberg EK, Vandenberg SR, Barchas JD, Herman MM
• An experimental mouse testicular teratoma as a model for neuroepithelial neoplasia and differentiation. II. Electron microscopy.
  The American journal of pathology 1975 Herman MM, Sipe JC, Rubinstein LJ, Vandenberg SR, Spence AM, Vraa-Jensen J
• Intracisternal A-particles in transplantable murine teratomas.
  Beitrage zur Pathologie 1975 Spence AM, Vandenberg SR, Herman MM
• An experimental mouse testicular teratoma as a model for neuroepithelial neoplasia and differentiation. I. Light microscopic and tissue and organ culture observations.
  The American journal of pathology 1975 VandenBerg SR, Herman MM, Ludwin SK, Bignami A