Saunak Sen, PhD, MS
Professor
Epidemiology & Biostatistics
School of Medicine

I am interested in statistical approaches to dissecting the genetic basis of biological systems. Much of my recent methodological work has focused on statistical methods for quantitative trait loci (QTL) in experimental crosses. This includes work on multiple imputation, study design, and statistical software.

Websites

Show all (1) Hide

• Website (biostat.ucsf.edu)

Grants and Projects

Show all (2) Hide

• A Unified High Performance Web Service for Systems Genetics and Precision Medicine, NIH, 2017-2025
• Statistical Methods for Experimental Genome Populations, NIH, 2007-2013

Publications (117)

Top publication keywords:
Halogenated Diphenyl EthersModels, GeneticReverse GeneticsSoftwareMutagenesisQuantitative Trait LociQuantitative Trait, HeritableCaprylatesCrosses, GeneticArabidopsisGenotypeAsthmaFetal DevelopmentChromosome MappingMaternal Exposure

• BulkLMM: Real-time genome scans for multiple quantitative traits using linear mixed models.
  bioRxiv : the preprint server for biology 2023 Yu Z, Farage G, Williams RW, Broman KW, Sen S
• Sex- and age-dependent genetics of longevity in a heterogeneous mouse population.
  Science (New York, N.Y.) 2022 Bou Sleiman M, Roy S, Gao AW, Sadler MC, von Alvensleben GVG, Li H, Sen S, Harrison DE, Nelson JF, Strong R, Miller RA, Kutalik Z, Williams RW, Auwerx J
• Speeding up eQTL scans in the BXD population using GPUs.
  G3 (Bethesda, Md.) 2021 Trotter C, Kim H, Farage G, Prins P, Williams RW, Broman KW, Sen S
• Gene-by-environment modulation of lifespan and weight gain in the murine BXD family.
  Nature metabolism 2021 Roy S, Sleiman MB, Jha P, Ingels JF, Chapman CJ, McCarty MS, Ziebarth JD, Hook M, Sun A, Zhao W, Huang J, Neuner SM, Wilmott LA, Shapaker TM, Centeno AG, Ashbrook DG, Mulligan MK, Kaczorowski CC, …
• Estimating the Effect of Social Distancing Interventions on COVID-19 in the United States.
  American journal of epidemiology 2021 Olney AM, Smith J, Sen S, Thomas F, Unwin HJT

Show all (112 more) Hide

• Organophosphate Flame Retardants, Highly Fluorinated Chemicals, and Biomarkers of Placental Development and Disease During Mid-Gestation.
  Toxicological sciences : an official journal of the Society of Toxicology 2021 Varshavsky JR, Robinson JF, Zhou Y, Puckett KA, Kwan E, Buarpung S, Aburajab R, Gaw SL, Sen S, Gao S, Smith SC, Park JS, Zakharevich I, Gerona RR, Fisher SJ, Woodruff TJ
• Identification of fibronectin 1 as a candidate genetic modifier in a Col4a1 mutant mouse model of Gould syndrome.
  Disease models & mechanisms 2021 Mao M, Popli T, Jeanne M, Hoff K, Sen S, Gould DB
• Importance of Multiple Reinforcing Comments and Areas for Change in Optimizing Dietary and Exercise Self-Monitoring Feedback in Behavioral Weight Loss Programs: Factorial Design.
  Journal of medical Internet research 2020 Krukowski R, Kim H, Stansbury M, Li Q, Sen S, Farage G, West D
• Racial/ethnic and geographic differences in polybrominated diphenyl ether (PBDE) levels across maternal, placental, and fetal tissues during mid-gestation.
  Scientific reports 2020 Varshavsky JR, Sen S, Robinson JF, Smith SC, Frankenfield J, Wang Y, Yeh G, Park JS, Fisher SJ, Woodruff TJ
• Association of polybrominated diphenyl ether (PBDE) levels with biomarkers of placental development and disease during mid-gestation.
  Environmental health : a global access science source 2020 Varshavsky JR, Robinson JF, Zhou Y, Puckett KA, Kwan E, Buarpung S, Aburajab R, Gaw SL, Sen S, Smith SC, Frankenfield J, Park JS, Fisher SJ, Woodruff TJ
• Matrix Linear Models for High-Throughput Chemical Genetic Screens.
  Genetics 2019 Liang JW, Nichols RJ, Sen S
• Cleaning Genotype Data from Diversity Outbred Mice.
  G3 (Bethesda, Md.) 2019 Broman KW, Gatti DM, Svenson KL, Sen S, Churchill GA
• Genome-wide association study of inhaled corticosteroid response in admixed children with asthma.
  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2019 Hernandez-Pacheco N, Farzan N, Francis B, Karimi L, Repnik K, Vijverberg SJ, Soares P, Schieck M, Gorenjak M, Forno E, Eng C, Oh SS, Pérez-Méndez L, Berce V, Tavendale R, Samedy LA, Hunstman S, Hu D, …
• Acculturation is associated with asthma burden and pulmonary function in Latino youth: The GALA II study.
  The Journal of allergy and clinical immunology 2019 Thakur N, Borrell LN, Ye M, Oh SS, Eng C, Meade K, Avila PC, Farber HJ, Serebrisky D, Brigino-Buenaventura E, Rodriguez-Cintron W, Kumar R, Bibbins-Domingo K, Thyne S, Sen S, Rodriguez-Santana JR, …
• R/qtl2: Software for Mapping Quantitative Trait Loci with High-Dimensional Data and Multiparent Populations.
  Genetics 2018 Broman KW, Gatti DM, Simecek P, Furlotte NA, Prins P, Sen S, Yandell BS, Churchill GA
• An admixture mapping meta-analysis implicates genetic variation at 18q21 with asthma susceptibility in Latinos.
  The Journal of allergy and clinical immunology 2018 Gignoux CR, Torgerson DG, Pino-Yanes M, Uricchio LH, Galanter J, Roth LA, Eng C, Hu D, Nguyen EA, Huntsman S, Mathias RA, Kumar R, Rodriguez-Santana J, Thakur N, Oh SS, McGarry M, Moreno-Estrada A, …
• Whole-Genome Sequencing of Pharmacogenetic Drug Response in Racially Diverse Children with Asthma.
  American journal of respiratory and critical care medicine 2018 Mak ACY, White MJ, Eckalbar WL, Szpiech ZA, Oh SS, Pino-Yanes M, Hu D, Goddard P, Huntsman S, Galanter J, Wu AC, Himes BE, Germer S, Vogel JM, Bunting KL, Eng C, Salazar S, Keys KL, Liberto J, Nuckton…
• Secondhand smoke exposure and asthma outcomes among African-American and Latino children with asthma.
  Thorax 2018 Neophytou AM, Oh SS, White MJ, Mak ACY, Hu D, Huntsman S, Eng C, Serebrisky D, Borrell LN, Farber HJ, Meade K, Davis A, Avila PC, Thyne SM, Rodríguez-Cintrón W, Rodríguez-Santana JR, Kumar R, Brigino-…
• Developmental PBDE Exposure and IQ/ADHD in Childhood: A Systematic Review and Meta-analysis.
  Environmental health perspectives 2017 Lam J, Lanphear BP, Bellinger D, Axelrad DA, McPartland J, Sutton P, Davidson L, Daniels N, Sen S, Woodruff TJ
• Cumulative effects of prenatal-exposure to exogenous chemicals and psychosocial stress on fetal growth: Systematic-review of the human and animal evidence.
  PloS one 2017 Vesterinen HM, Morello-Frosch R, Sen S, Zeise L, Woodruff TJ
• Identification of a novel locus associated with skin colour in African-admixed populations.
  Scientific reports 2017 Hernandez-Pacheco N, Flores C, Alonso S, Eng C, Mak AC, Hunstman S, Hu D, White MJ, Oh SS, Meade K, Farber HJ, Avila PC, Serebrisky D, Thyne SM, Brigino-Buenaventura E, Rodriguez-Cintron W, Sen S, …
• Breastfeeding associated with higher lung function in African American youths with asthma.
  The Journal of asthma : official journal of the Association for the Care of Asthma 2016 Oh SS, Du R, Zeiger AM, McGarry ME, Hu D, Thakur N, Pino-Yanes M, Galanter JM, Eng C, Nishimura KK, Huntsman S, Farber HJ, Meade K, Avila P, Serebrisky D, Bibbins-Domingo K, Lenoir MA, Ford JG, …
• Perceived Discrimination Associated With Asthma and Related Outcomes in Minority Youth: The GALA II and SAGE II Studies.
  Chest 2016 Thakur N, Barcelo NE, Borrell LN, Singh S, Eng C, Davis A, Meade K, LeNoir MA, Avila PC, Farber HJ, Serebrisky D, Brigino-Buenaventura E, Rodriguez-Cintron W, Thyne S, Rodriguez-Santana JR, Sen S, …
• Association of a PAI-1 Gene Polymorphism and Early Life Infections with Asthma Risk, Exacerbations, and Reduced Lung Function.
  PloS one 2016 Cho SH, Min JY, Kim DY, Oh SS, Torgerson DR, Pino-Yanes M, Hu D, Sen S, Huntsman S, Eng C, Farber HJ, Rodriguez-Cintron W, Rodriguez-Santana JR, Serebrisky D, Thyne SM, Borrell LN, Williams LK, DuPont…
• Preoperative Frailty Is Associated With Discharge to Skilled or Assisted Living Facilities After Urologic Procedures of Varying Complexity.
  Urology 2016 Suskind AM, Jin C, Cooperberg MR, Finlayson E, Boscardin WJ, Sen S, Walter LC
• Early-life ozone exposure associated with asthma without sensitization in Latino children.
  The Journal of allergy and clinical immunology 2016 Nishimura KK, Iwanaga K, Oh SS, Pino-Yanes M, Eng C, Keswani A, Roth LA, Nguyen EA, Thyne SM, Farber HJ, Serebrisky D, Meade K, LeNoir MA, Rodriguez-Cintron W, Borrell LN, Bibbins-Domingo K, Lurmann F…
• Air Pollution and Lung Function in Minority Youth with Asthma in the GALA II (Genes-Environments and Admixture in Latino Americans) and SAGE II (Study of African Americans, Asthma, Genes, and Environments) Studies.
  American journal of respiratory and critical care medicine 2016 Neophytou AM, White MJ, Oh SS, Thakur N, Galanter JM, Nishimura KK, Pino-Yanes M, Torgerson DG, Gignoux CR, Eng C, Nguyen EA, Hu D, Mak AC, Kumar R, Seibold MA, Davis A, Farber HJ, Meade K, Avila PC, …
• Sensitization to mouse and cockroach allergens and asthma morbidity in urban minority youth: Genes-environments and Admixture in Latino American (GALA-II) and Study of African-Americans, Asthma, Genes, and Environments (SAGE-II).
  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2016 Fishbein AB, Lee TA, Cai M, Oh SS, Eng C, Hu D, Huntsman S, Farber HJ, Serebrisky D, Silverberg J, Williams LK, Seibold MA, Sen S, Borrell LN, Avila P, Rodriguez-Cintron W, Rodriguez-Santana JR, …
• Application of the Navigation Guide systematic review methodology to the evidence for developmental and reproductive toxicity of triclosan.
  Environment international 2016 Johnson PI, Koustas E, Vesterinen HM, Sutton P, Atchley DS, Kim AN, Campbell M, Donald JM, Sen S, Bero L, Zeise L, Woodruff TJ
• Impact of frailty on complications in patients undergoing common urological procedures: a study from the American College of Surgeons National Surgical Quality Improvement database.
  BJU international 2016 Suskind AM, Walter LC, Jin C, Boscardin J, Sen S, Cooperberg MR, Finlayson E
• Functional decline in patients with cirrhosis awaiting liver transplantation: Results from the functional assessment in liver transplantation (FrAILT) study.
  Hepatology (Baltimore, Md.) 2015 Lai JC, Dodge JL, Sen S, Covinsky K, Feng S
• Fetal growth and maternal glomerular filtration rate: a systematic review.
  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2015 Vesterinen HM, Johnson PI, Atchley DS, Sutton P, Lam J, Zlatnik MG, Sen S, Woodruff TJ
• Identification and Correction of Sample Mix-Ups in Expression Genetic Data: A Case Study.
  G3 (Bethesda, Md.) 2015 Broman KW, Keller MP, Broman AT, Kendziorski C, Yandell BS, Sen S, Attie AD
• Obesity and bronchodilator response in black and Hispanic children and adolescents with asthma.
  Chest 2015 McGarry ME, Castellanos E, Thakur N, Oh SS, Eng C, Davis A, Meade K, LeNoir MA, Avila PC, Farber HJ, Serebrisky D, Brigino-Buenaventura E, Rodriguez-Cintron W, Kumar R, Bibbins-Domingo K, Thyne SM, …
• Exploiting Differential Gene Expression and Epistasis to Discover Candidate Genes for Drought-Associated QTLs in Arabidopsis thaliana.
  The Plant cell 2015 Lovell JT, Mullen JL, Lowry DB, Awole K, Richards JH, Sen S, Verslues PE, Juenger TE, McKay JK
• Mapk/Erk activation in an animal model of social deficits shows a possible link to autism.
  Molecular autism 2014 Faridar A, Jones-Davis D, Rider E, Li J, Gobius I, Morcom L, Richards LJ, Sen S, Sherr EH
• Genome-wide association study and admixture mapping reveal new loci associated with total IgE levels in Latinos.
  The Journal of allergy and clinical immunology 2014 Pino-Yanes M, Gignoux CR, Galanter JM, Levin AM, Campbell CD, Eng C, Huntsman S, Nishimura KK, Gourraud PA, Mohajeri K, O'Roak BJ, Hu D, Mathias RA, Nguyen EA, Roth LA, Padhukasahasram B, Moreno-…
• The association between body composition and cystatin C in South Asians: results from the MASALA study.
  Obesity research & clinical practice 2014 Shah AD, Schmidt H, Sen S, Shlipak MG, Kanaya AM
• Genetic ancestry influences asthma susceptibility and lung function among Latinos.
  The Journal of allergy and clinical immunology 2014 Pino-Yanes M, Thakur N, Gignoux CR, Galanter JM, Roth LA, Eng C, Nishimura KK, Oh SS, Vora H, Huntsman S, Nguyen EA, Hu D, Drake KA, Conti DV, Moreno-Estrada A, Sandoval K, Winkler CA, Borrell LN, …
• The Navigation Guide - evidence-based medicine meets environmental health: integration of animal and human evidence for PFOA effects on fetal growth.
  Environmental health perspectives 2014 Lam J, Koustas E, Sutton P, Johnson PI, Atchley DS, Sen S, Robinson KA, Axelrad DA, Woodruff TJ
• The Navigation Guide - evidence-based medicine meets environmental health: systematic review of human evidence for PFOA effects on fetal growth.
  Environmental health perspectives 2014 Johnson PI, Sutton P, Atchley DS, Koustas E, Lam J, Sen S, Robinson KA, Axelrad DA, Woodruff TJ
• The Navigation Guide - evidence-based medicine meets environmental health: systematic review of nonhuman evidence for PFOA effects on fetal growth.
  Environmental health perspectives 2014 Koustas E, Lam J, Sutton P, Johnson PI, Atchley DS, Sen S, Robinson KA, Axelrad DA, Woodruff TJ
• Socioeconomic status and asthma control in African American youth in SAGE II.
  The Journal of asthma : official journal of the Association for the Care of Asthma 2014 Thakur N, Martin M, Castellanos E, Oh SS, Roth LA, Eng C, Brigino-Buenaventura E, Davis A, Meade K, LeNoir MA, Farber HJ, Thyne S, Sen S, Bibbins-Domingo K, Borrell LN, Burchard EG
• Characteristics of adolescent intermittent and daily smokers.
  Addictive behaviors 2014 Rubinstein ML, Rait MA, Sen S, Shiffman S
• Genome-wide association study and admixture mapping identify different asthma-associated loci in Latinos: the Genes-environments & Admixture in Latino Americans study.
  The Journal of allergy and clinical immunology 2014 Galanter JM, Gignoux CR, Torgerson DG, Roth LA, Eng C, Oh SS, Nguyen EA, Drake KA, Huntsman S, Hu D, Sen S, Davis A, Farber HJ, Avila PC, Brigino-Buenaventura E, LeNoir MA, Meade K, Serebrisky D, …
• Socioeconomic status and childhood asthma in urban minority youths. The GALA II and SAGE II studies.
  American journal of respiratory and critical care medicine 2013 Thakur N, Oh SS, Nguyen EA, Martin M, Roth LA, Galanter J, Gignoux CR, Eng C, Davis A, Meade K, LeNoir MA, Avila PC, Farber HJ, Serebrisky D, Brigino-Buenaventura E, Rodriguez-Cintron W, Kumar R, …
• Bisphenol-A (BPA), BPA glucuronide, and BPA sulfate in midgestation umbilical cord serum in a northern and central California population.
  Environmental science & technology 2013 Gerona RR, Woodruff TJ, Dickenson CA, Pan J, Schwartz JM, Sen S, Friesen MW, Fujimoto VY, Hunt PA
• Development of a next-generation NIL library in Arabidopsis thaliana for dissecting complex traits.
  BMC genomics 2013 Fletcher RS, Mullen JL, Yoder S, Bauerle WL, Reuning G, Sen S, Meyer E, Juenger TE, McKay JK
• Expression quantitative trait locus mapping across water availability environments reveals contrasting associations with genomic features in Arabidopsis.
  The Plant cell 2013 Lowry DB, Logan TL, Santuari L, Hardtke CS, Richards JH, DeRose-Wilson LJ, McKay JK, Sen S, Juenger TE
• A genome-wide association study of bronchodilator response in Latinos implicates rare variants.
  The Journal of allergy and clinical immunology 2013 Drake KA, Torgerson DG, Gignoux CR, Galanter JM, Roth LA, Huntsman S, Eng C, Oh SS, Yee SW, Lin L, Bustamante CD, Moreno-Estrada A, Sandoval K, Davis A, Borrell LN, Farber HJ, Kumar R, Avila PC, …
• Early-life air pollution and asthma risk in minority children. The GALA II and SAGE II studies.
  American journal of respiratory and critical care medicine 2013 Nishimura KK, Galanter JM, Roth LA, Oh SS, Thakur N, Nguyen EA, Thyne S, Farber HJ, Serebrisky D, Kumar R, Brigino-Buenaventura E, Davis A, LeNoir MA, Meade K, Rodriguez-Cintron W, Avila PC, Borrell …
• Pleiotropy of FRIGIDA enhances the potential for multivariate adaptation.
  Proceedings. Biological sciences 2013 Lovell JT, Juenger TE, Michaels SD, Lasky JR, Platt A, Richards JH, Yu X, Easlon HM, Sen S, McKay JK
• Quantitative trait loci for interhemispheric commissure development and social behaviors in the BTBR T⁺ tf/J mouse model of autism.
  PloS one 2013 Jones-Davis DM, Yang M, Rider E, Osbun NC, da Gente GJ, Li J, Katz AM, Weber MD, Sen S, Crawley J, Sherr EH
• Childhood obesity and asthma control in the GALA II and SAGE II studies.
  American journal of respiratory and critical care medicine 2013 Borrell LN, Nguyen EA, Roth LA, Oh SS, Tcheurekdjian H, Sen S, Davis A, Farber HJ, Avila PC, Brigino-Buenaventura E, Lenoir MA, Lurmann F, Meade K, Serebrisky D, Rodriguez-Cintron W, Kumar R, …
• Nicotine metabolism and addiction among adolescent smokers.
  Addiction (Abingdon, England) 2012 Rubinstein ML, Shiffman S, Moscicki AB, Rait MA, Sen S, Benowitz NL
• Genome-wide DNA methylation profiling of CpG islands in hypospadias.
  The Journal of urology 2012 Choudhry S, Deshpande A, Qiao L, Beckman K, Sen S, Baskin LS
• Mapping quantitative trait loci onto a phylogenetic tree.
  Genetics 2012 Broman KW, Kim S, Sen S, Ané C, Payseur BA
• Genetic ancestry-smoking interactions and lung function in African Americans: a cohort study.
  PloS one 2012 Aldrich MC, Kumar R, Colangelo LA, Williams LK, Sen S, Kritchevsky SB, Meibohm B, Galanter J, Hu D, Gignoux CR, Liu Y, Harris TB, Ziv E, Zmuda J, Garcia M, Leak TS, Foreman MG, Smith LJ, Fornage M, …
• Effect of secondhand smoke on asthma control among black and Latino children.
  The Journal of allergy and clinical immunology 2012 Oh SS, Tcheurekdjian H, Roth LA, Nguyen EA, Sen S, Galanter JM, Davis A, Farber HJ, Gilliland FD, Kumar R, Avila PC, Brigino-Buenaventura E, Chapela R, Ford JG, LeNoir MA, Lurmann F, Meade K, …
• Genetic dissection of a model complex trait using the Drosophila Synthetic Population Resource.
  Genome research 2012 King EG, Merkes CM, McNeil CL, Hoofer SR, Sen S, Broman KW, Long AD, Macdonald SJ
• Physiological genomics of response to soil drying in diverse Arabidopsis accessions.
  The Plant cell 2012 Des Marais DL, McKay JK, Richards JH, Sen S, Wayne T, Juenger TE
• Sequence-based classification using discriminatory motif feature selection.
  PloS one 2011 Xiong H, Capurso D, Sen S, Segal MR
• A flexible estimating equations approach for mapping function-valued traits.
  Genetics 2011 Xiong H, Goulding EH, Carlson EJ, Tecott LH, McCulloch CE, Sen S
• Cosmopolitan and ethnic-specific replication of genetic risk factors for asthma in 2 Latino populations.
  The Journal of allergy and clinical immunology 2011 Galanter JM, Torgerson D, Gignoux CR, Sen S, Roth LA, Via M, Aldrich MC, Eng C, Huntsman S, Rodriguez-Santana J, Rodriguez-Cintrón W, Chapela R, Ford JG, Burchard EG
• Use of Google Insights for Search to track seasonal and geographic kidney stone incidence in the United States.
  Urology 2011 Breyer BN, Sen S, Aaronson DS, Stoller ML, Erickson BA, Eisenberg ML
• Phenotypic landscape of a bacterial cell.
  Cell 2010 Nichols RJ, Sen S, Choo YJ, Beltrao P, Zietek M, Chaba R, Lee S, Kazmierczak KM, Lee KJ, Wong A, Shales M, Lovett S, Winkler ME, Krogan NJ, Typas A, Gross CA
• Genetic ancestry in lung-function predictions.
  The New England journal of medicine 2010 Kumar R, Seibold MA, Aldrich MC, Williams LK, Reiner AP, Colangelo L, Galanter J, Gignoux C, Hu D, Sen S, Choudhry S, Peterson EL, Rodriguez-Santana J, Rodriguez-Cintron W, Nalls MA, Leak TS, O'Meara …
• Exploring genetic and expression differences between physiologically extreme ecotypes: comparative genomic hybridization and gene expression studies of Kas-1 and Tsu-1 accessions of Arabidopsis thaliana.
  Plant, cell & environment 2010 Juenger TE, Sen S, Bray E, Stahl E, Wayne T, McKay J, Richards JH
• Strain background modifies phenotypes in the ATP8B1-deficient mouse.
  PloS one 2010 Shah S, Sanford UR, Vargas JC, Xu H, Groen A, Paulusma CC, Grenert JP, Pawlikowska L, Sen S, Elferink RP, Bull LN
• The role of LTA4H and ALOX5AP genes in the risk for asthma in Latinos.
  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2010 Via M, De Giacomo A, Corvol H, Eng C, Seibold MA, Gillett C, Galanter J, Sen S, Tcheurekdjian H, Chapela R, Rodríguez-Santana JR, Rodríguez-Cintrón W, Thyne S, Avila PC, Choudhry S, González Burchard …
• A guide to QTL mapping using R/qtl
  2009 Broman KW, Sen S
• Patient satisfaction after treatment of nonmelanoma skin cancer.
  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 2009 Asgari MM, Bertenthal D, Sen S, Sahay A, Chren MM
• Polymorphisms of MLH1 in benign prostatic hyperplasia and sporadic prostate cancer.
  Biochemical and biophysical research communications 2009 Tanaka Y, Zaman MS, Majid S, Liu J, Kawakami K, Shiina H, Tokizane T, Dahiya AV, Sen S, Nakajima K
• Sample size calculations for evaluating mediation.
  Statistics in medicine 2009 Vittinghoff E, Sen S, McCulloch CE
• Selective genotyping and phenotyping strategies in a complex trait context.
  Genetics 2009 Sen S, Johannes F, Broman KW
• A model selection approach for the identification of quantitative trait loci in experimental crosses, allowing epistasis.
  Genetics 2008 Manichaikul A, Moon JY, Sen S, Yandell BS, Broman KW
• Associations of interleukin-6, C-reactive protein and serum amyloid A with mortality in haemodialysis patients.
  Nephrology (Carlton, Vic.) 2008 Wetmore JB, Lovett DH, Hung AM, Cook-Wiens G, Mahnken JD, Sen S, Johansen KL
• Genetics of drought adaptation in Arabidopsis thaliana II. QTL analysis of a new mapping population, KAS-1 x TSU-1.
  Evolution; international journal of organic evolution 2008 McKay JK, Richards JH, Nemali KS, Sen S, Mitchell-Olds T, Boles S, Stahl EA, Wayne T, Juenger TE
• An african-specific functional polymorphism in KCNMB1 shows sex-specific association with asthma severity.
  Human molecular genetics 2008 Seibold MA, Wang B, Eng C, Kumar G, Beckman KB, Sen S, Choudhry S, Meade K, Lenoir M, Watson HG, Thyne S, Williams LK, Kumar R, Weiss KB, Grammer LC, Avila PC, Schleimer RP, Burchard EG, Brenner R
• The timing of eruption of the primary dentition in Nigerian children.
  American journal of physical anthropology 2007 Folayan M, Owotade F, Adejuyigbe E, Sen S, Lawal B, Ndukwe K
• Effects of hospital procedure volume and resident training on clinical outcomes and resource use in radical retropubic prostatectomy surgery in the Department of Veterans Affairs.
  The Journal of urology 2007 Ku TS, Kane CJ, Sen S, Henderson WG, Dudley RA, Cason BA
• Predictors of skin-related quality of life after treatment of cutaneous basal cell carcinoma and squamous cell carcinoma.
  Archives of dermatology 2007 Chen T, Bertenthal D, Sahay A, Sen S, Chren MM
• Estrogen receptor genotype and risk of cognitive impairment in elders: findings from the Health ABC study.
  Neurobiology of aging 2007 Yaffe K, Lindquist K, Sen S, Cauley J, Ferrell R, Penninx B, Harris T, Li R, Cummings SR
• Significance thresholds for quantitative trait locus mapping under selective genotyping.
  Genetics 2007 Manichaikul A, Palmer AA, Sen S, Broman KW
• Childhood social and economic well-being and health in older age.
  American journal of epidemiology 2007 Moody-Ayers S, Lindquist K, Sen S, Covinsky KE
• Mouse chromosome 7 harbors a quantitative trait locus for isoflurane minimum alveolar concentration.
  Anesthesia and analgesia 2007 Cascio M, Xing Y, Gong D, Popovich J, Eger EI, Sen S, Peltz G, Sonner JM
• Sequential quantitative trait locus mapping in experimental crosses.
  Statistical applications in genetics and molecular biology 2007 Satagopan JM, Sen S, Churchill GA
• Geography matters: relationships among urban residential segregation, dialysis facilities, and patient outcomes.
  Annals of internal medicine 2007 Rodriguez RA, Sen S, Mehta K, Moody-Ayers S, Bacchetti P, O'Hare AM
• Bringing the war back home: mental health disorders among 103,788 US veterans returning from Iraq and Afghanistan seen at Department of Veterans Affairs facilities.
  Archives of internal medicine 2007 Seal KH, Bertenthal D, Miner CR, Sen S, Marmar C
• R/qtlDesign: inbred line cross experimental design.
  Mammalian genome : official journal of the International Mammalian Genome Society 2007 Sen S, Satagopan JM, Broman KW, Churchill GA
• Quality-of-life outcomes of treatments for cutaneous basal cell carcinoma and squamous cell carcinoma.
  The Journal of investigative dermatology 2007 Chren MM, Sahay AP, Bertenthal DS, Sen S, Landefeld CS
• The relationship of indwelling urinary catheters to death, length of hospital stay, functional decline, and nursing home admission in hospitalized older medical patients.
  Journal of the American Geriatrics Society 2007 Holroyd-Leduc JM, Sen S, Bertenthal D, Sands LP, Palmer RM, Kresevic DM, Covinsky KE, Seth Landefeld C
• Conflicts and concordance between measures of medication prescribing quality.
  Medical care 2007 Steinman MA, Rosenthal GE, Landefeld CS, Bertenthal D, Sen S, Kaboli PJ
• Self-rated health among women with coronary disease: depression is as important as recent cardiovascular events.
  American heart journal 2006 Ruo B, Bertenthal D, Sen S, Bittner V, Ireland CC, Hlatky MA
• The X chromosome in quantitative trait locus mapping.
  Genetics 2006 Broman KW, Sen S, Owens SE, Manichaikul A, Southard-Smith EM, Churchill GA
• Polypharmacy and prescribing quality in older people.
  Journal of the American Geriatrics Society 2006 Steinman MA, Landefeld CS, Rosenthal GE, Berthenthal D, Sen S, Kaboli PJ
• An angiotensin converting enzyme haplotype predicts survival in patients with end stage renal disease.
  Human genetics 2006 Wetmore JB, Johansen KL, Sen S, Hung AM, Lovett DH
• Poor performance of bootstrap confidence intervals for the location of a quantitative trait locus.
  Genetics 2006 Manichaikul A, Dupuis J, Sen S, Broman KW
• Isolation and confirmation of a calcium excretion quantitative trait locus on chromosome 1 in genetic hypercalciuric stone-forming congenic rats.
  Journal of the American Society of Nephrology : JASN 2006 Hoopes RR, Middleton FA, Sen S, Hueber PA, Reid R, Bushinsky DA, Scheinman SJ
• Mortality risk stratification in chronic kidney disease: one size for all ages?
  Journal of the American Society of Nephrology : JASN 2006 O'Hare AM, Bertenthal D, Covinsky KE, Landefeld CS, Sen S, Mehta K, Steinman MA, Borzecki A, Walter LC
• Renal insufficiency and use of revascularization among a national cohort of men with advanced lower extremity peripheral arterial disease.
  Clinical journal of the American Society of Nephrology : CJASN 2006 O'Hare AM, Bertenthal D, Sidawy AN, Shlipak MG, Sen S, Chren MM
• Quantitative trait loci for femoral and lumbar vertebral bone mineral density in C57BL/6J and C3h/HeJ inbred strains of mice. (2001).
  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2005 Beamer WG, Shultz KL, Donahue LR, Churchill GA, Sen S, Wergedal JR, Baylink DJ, Rosen CJ
• Interleukin-1 gene cluster polymorphisms predict risk of ESRD.
  Kidney international 2005 Wetmore JB, Hung AM, Lovett DH, Sen S, Quershy O, Johansen KL
• Genetic modifiers interact with Cpe(fat) to affect body weight, adiposity, and hyperglycemia.
  Physiological genomics 2005 Collin GB, Maddatu TP, Sen S, Naggert JK
• Quantitative trait locus study design from an information perspective.
  Genetics 2005 Sen S, Satagopan JM, Churchill GA
• Epistasis and genotype-environment interaction for quantitative trait loci affecting flowering time in Arabidopsis thaliana.
  Genetica 2005 Juenger TE, Sen S, Stowe KA, Simms EL
• Quantitative trait loci affecting delta13C and response to differential water availibility in Arabidopsis thaliana.
  Evolution; international journal of organic evolution 2005 Hausmann NJ, Juenger TE, Sen S, Stowe KA, Dawson TE, Simms EL
• Impact of renal insufficiency on mortality in advanced lower extremity peripheral arterial disease.
  Journal of the American Society of Nephrology : JASN 2004 O'Hare AM, Bertenthal D, Shlipak MG, Sen S, Chren MM
• Locating Ath8, a locus for murine atherosclerosis susceptibility and testing several of its candidate genes in mice and humans.
  Atherosclerosis 2004 Korstanje R, Eriksson P, Samnegård A, Olsson PG, Forsman-Semb K, Sen S, Churchill GA, Rollins J, Harris S, Hamsten A, Paigen B
• Obesity, leptin resistance, and the effects of insulin reduction.
  International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2004 Lustig RH, Sen S, Soberman JE, Velasquez-Mieyer PA
• QTL analysis for discovery of genes involved in drug responses.
  Current drug targets. Infectious disorders 2004 Sen S, Ferdig M
• Mapping quantitative trait loci for vertebral trabecular bone volume fraction and microarchitecture in mice.
  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2003 Bouxsein ML, Uchiyama T, Rosen CJ, Shultz KL, Donahue LR, Turner CH, Sen S, Churchill GA, Müller R, Beamer WG
• Quantitative trait loci for hypercalciuria in a rat model of kidney stone disease.
  Journal of the American Society of Nephrology : JASN 2003 Hoopes RR, Reid R, Sen S, Szpirer C, Dixon P, Pannett AA, Thakker RV, Bushinsky DA, Scheinman SJ
• R/qtl: QTL mapping in experimental crosses.
  Bioinformatics (Oxford, England) 2003 Broman KW, Wu H, Sen S, Churchill GA
• A statistical framework for quantitative trait mapping.
  Genetics 2001 Sen S, Churchill GA
• Quantitative trait loci for femoral and lumbar vertebral bone mineral density in C57BL/6J and C3H/HeJ inbred strains of mice.
  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2001 Beamer WG, Shultz KL, Donahue LR, Churchill GA, Sen S, Wergedal JR, Baylink DJ, Rosen CJ
• Genetic analysis of a new mouse model for non-insulin-dependent diabetes.
  Genomics 2001 Kim JH, Sen S, Avery CS, Simpson E, Chandler P, Nishina PM, Churchill GA, Naggert JK