Sanjeev Ranade, PhD
Collaborator
Business Service Ctr
Chancellor/EVC/FAS

Publications (21)

Top publication keywords:
Endothelial CellsMerkel CellsMechanotransduction, CellularEpigenomicsBasic Helix-Loop-Helix Transcription FactorsThyroid Nuclear Factor 1Embryonic DevelopmentCardiovascular SystemIon Channel GatingIon TransportSensationHomeobox Protein Nkx-2.5SkinIon ChannelsTouch

• A genome-wide CRISPR screen identifies BRD4 as a regulator of cardiomyocyte differentiation.
  Nature Cardiovascular Research 2024 Arun Padmanabhan, T. Yvanka de Soysa, Angelo Pelonero, Valerie Sapp, Parisha P. Shah, Qiaohong Wang, Li Li, Clara Youngna Lee, Nandhini Sadagopan, Tomohiro Nishino, Lin Ye, Rachel Yang, Ashley Karnay,…
• Single-cell multimodal analyses reveal epigenomic and transcriptomic basis for birth defects in maternal diabetes.
  Nature Cardiovascular Research 2023 Tomohiro Nishino, Sanjeev S. Ranade, Angelo Pelonero, Benjamin J. van Soldt, Lin Ye, Michael Alexanian, Frances Koback, Yu Huang, Langley Grace Wallace, Nandhini Sadagopan, Adrienne Lam, Lyandysha V. …
• A Mesp1-dependent developmental breakpoint in transcriptional and epigenomic specification of early cardiac precursors.
  Development (Cambridge, England) 2023 Krup AL, Winchester SAB, Ranade SS, Agrawal A, Devine WP, Sinha T, Choudhary K, Dominguez MH, Thomas R, Black BL, Srivastava D, Bruneau BG
• Abstract 14797: Single Cell Multi-Modal Analyses Reveal Epigenomic and Transcriptomic Basis Underlying Cardiac Defects in Maternal Diabetes.
  Circulation 2022 Tomohiro Nishino, Sanjeev Ranade, Pelonero Angelo, Benjamin J van Soldt, Lin Ye, Michael Alexanian, Frances Koback, Yu Huang, Nandhini Sadagopan, Arun Padmanabhan, Reuben Thomas, Joke van Bemmel, …
• A transcriptional switch governs fibroblast activation in heart disease.
  Nature 2021 Alexanian M, Przytycki PF, Micheletti R, Padmanabhan A, Ye L, Travers JG, Gonzalez-Teran B, Silva AC, Duan Q, Ranade SS, Felix F, Linares-Saldana R, Li L, Lee CY, Sadagopan N, Pelonero A, Huang Y, …

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• Network-based screen in iPSC-derived cells reveals therapeutic candidate for heart valve disease.
  Science (New York, N.Y.) 2020 Theodoris CV, Zhou P, Liu L, Zhang Y, Nishino T, Huang Y, Kostina A, Ranade SS, Gifford CA, Uspenskiy V, Malashicheva A, Ding S, Srivastava D
• Single-cell analysis of cardiogenesis reveals basis for organ-level developmental defects.
  Nature 2019 de Soysa TY, Ranade SS, Okawa S, Ravichandran S, Huang Y, Salunga HT, Schricker A, Del Sol A, Gifford CA, Srivastava D
• Oligogenic inheritance of a human heart disease involving a genetic modifier.
  Science (New York, N.Y.) 2019 Gifford CA, Ranade SS, Samarakoon R, Salunga HT, de Soysa TY, Huang Y, Zhou P, Elfenbein A, Wyman SK, Bui YK, Cordes Metzler KR, Ursell P, Ivey KN, Srivastava D
• Mechanically activated ion channel PIEZO1 is required for lymphatic valve formation.
  Proceedings of the National Academy of Sciences of the United States of America 2018 Nonomura K, Lukacs V, Sweet DT, Goddard LM, Kanie A, Whitwam T, Ranade SS, Fujimori T, Kahn ML, Patapoutian A
• Long telomeres protect against age-dependent cardiac disease caused by NOTCH1 haploinsufficiency.
  The Journal of clinical investigation 2017 Theodoris CV, Mourkioti F, Huang Y, Ranade SS, Liu L, Blau HM, Srivastava D
• Piezo2 senses airway stretch and mediates lung inflation-induced apnoea.
  Nature 2016 Nonomura K, Woo SH, Chang RB, Gillich A, Qiu Z, Francisco AG, Ranade SS, Liberles SD, Patapoutian A
• Mechanosensory hair cells express two molecularly distinct mechanotransduction channels.
  Nature neuroscience 2016 Wu Z, Grillet N, Zhao B, Cunningham C, Harkins-Perry S, Coste B, Ranade S, Zebarjadi N, Beurg M, Fettiplace R, Patapoutian A, Mueller U
• Piezo1 in Smooth Muscle Cells Is Involved in Hypertension-Dependent Arterial Remodeling.
  Cell reports 2015 Retailleau K, Duprat F, Arhatte M, Ranade SS, Peyronnet R, Martins JR, Jodar M, Moro C, Offermanns S, Feng Y, Demolombe S, Patel A, Honoré E
• Mechanically Activated Ion Channels.
  Neuron 2015 Sanjeev S. Ranade, Ruhma Syeda, Ardem Patapoutian
• Mechanically Activated Ion Channels.
  Neuron 2015 Ranade SS, Syeda R, Patapoutian A
• Piezo1 links mechanical forces to red blood cell volume.
  eLife 2015 Cahalan SM, Lukacs V, Ranade SS, Chien S, Bandell M, Patapoutian A
• Piezo2 is the major transducer of mechanical forces for touch sensation in mice.
  Nature 2014 Ranade SS, Woo SH, Dubin AE, Moshourab RA, Wetzel C, Petrus M, Mathur J, Bégay V, Coste B, Mainquist J, Wilson AJ, Francisco AG, Reddy K, Qiu Z, Wood JN, Lewin GR, Patapoutian A
• Piezo1, a mechanically activated ion channel, is required for vascular development in mice.
  Proceedings of the National Academy of Sciences of the United States of America 2014 Ranade SS, Qiu Z, Woo SH, Hur SS, Murthy SE, Cahalan SM, Xu J, Mathur J, Bandell M, Coste B, Li YS, Chien S, Patapoutian A
• Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors.
  Nature 2014 Maksimovic S, Nakatani M, Baba Y, Nelson AM, Marshall KL, Wellnitz SA, Firozi P, Woo SH, Ranade S, Patapoutian A, Lumpkin EA
• Piezo2 is required for Merkel-cell mechanotransduction.
  Nature 2014 Woo SH, Ranade S, Weyer AD, Dubin AE, Baba Y, Qiu Z, Petrus M, Miyamoto T, Reddy K, Lumpkin EA, Stucky CL, Patapoutian A
• Piezo1 and Piezo2 are essential components of distinct mechanically activated cation channels.
  Science (New York, N.Y.) 2010 Coste B, Mathur J, Schmidt M, Earley TJ, Ranade S, Petrus MJ, Dubin AE, Patapoutian A