Sanghee Lee, PhD
Postdoctoral Scholar
Radiology
School of Medicine

Education & Training

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• Ph.D Radiochemistry and Biomedical Radiation Science Seoul National University 08/2021

Interests

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• Radiopharmaceuticals
• Radiochemistry
• Nano technology
• Organic chemistry

Publications (16)

Top publication keywords:
Receptors, GABAXanthenesAlzheimer DiseaseHeterocyclic Compounds, 2-RingFluorine RadioisotopesPositron-Emission TomographyDiscitisMuramic AcidsButyrylcholinesteraseAcetamidesReceptors, GABA-APeptidoglycanAcetylcholinesteraseCell WallOsteomyelitis

• Bioorthogonal Radiolabeling of Azide-Modified Bacteria Using [18F]FB-sulfo-DBCO.
  Bioconjugate chemistry 2024 Alanizi AA, Sorlin AM, Parker MFL, López-Álvarez M, Qin H, Lee SH, Blecha J, Rosenberg OS, Engel J, Ohliger MA, Flavell RR, Wilson DM
• Peptidoglycan-Targeted[18F]3,3,3-Trifluoro‑D‑alanineTracerforImagingBacterialInfection
  JACS Au 2024 Alexandre M. Sorlin, Marina López-Álvarez, Jacob Biboy, Joe Gray, Sarah J. Rabbitt,…
• Radiosynthesis and whole-body distribution in mice of a 18 F-labeled azepino[4,3-b]indole-1-one derivative with multimodal activity for the treatment of Alzheimer's disease.
  Archiv der Pharmazie 2023 Lee SH, Purgatorio R, Samarelli F, Catto M, Denora N, Morgese MG, Tucci P, Trabace L, Kim HW, Park HS, Kim SE, Lee BC, de Candia M, Altomare CD
• Imaging the Bacterial Cell Wall Using N-Acetyl Muramic Acid-Derived Positron Emission Tomography Radiotracers.
  ACS sensors 2023 Lee SH, Kim JM, López-Álvarez M, Wang C, Sorlin AM, Bobba KN, Pichardo-González PA, Blecha J, Seo Y, Flavell RR, Engel J, Ohliger MA, Wilson DM
• Evaluating the Performance of Pathogen-Targeted Positron Emission Tomography Radiotracers in a Rat Model of Vertebral Discitis-Osteomyelitis.
  The Journal of infectious diseases 2023 Parker MFL, López-Álvarez M, Alanizi AA, Luu JM, Polvoy I, Sorlin AM, Qin H, Lee S, Rabbitt SJ, Pichardo-González PA, Ordonez AA, Blecha J, Rosenberg OS, Flavell RR, Engel J, Jain SK, Ohliger MA, …

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• Designing novel anticancer sulfonamide based 2,5-disubstituted-1,3,4-thiadiazole derivatives as potential carbonic anhydrase inhibitor
  Journal of Molecular Structure 2021 Mujahid Abas, Ali Bahadur, Zaman Ashraf, Shahid Iqbal, Muhammad Shahid Riaz Rajoka, S.G. Rashid, Erum Jabeen, Zafar Iqbal, Qamar Abbas, Abdul Bais, Mubashir Hassan, Guocong Liu, Kejun Feng, Sanghee …
• Radiosynthesis and characterization of [18F]BS224: a next-generation TSPO PET ligand insensitive to the rs6971 polymorphism.
  European journal of nuclear medicine and molecular imaging 2021 Lee SH, Denora N, Laquintana V, Mangiatordi GF, Lopedota A, Lopalco A, Cutrignelli A, Franco M, Delre P, Song IH, Kim HW, Kim SB, Park HS, Kim K, Lee SY, Youn H, Lee BC, Kim SE
• Effect of Peptide Receptor Radionuclide Therapy in Combination with Temozolomide against Tumor Angiogenesis in a Glioblastoma Model.
  Cancers 2021 Lee SH, Choi JY, Jung JH, Song IH, Park HS, Denora N, Leonetti F, Kim SE, Lee BC
• TSPO Expression Modulatory Effect of Acetylcholinesterase Inhibitor in the Ischemic Stroke Rat Model.
  Cells 2021 Song YS, Lee SH, Jung JH, Song IH, Park HS, Moon BS, Kim SE, Lee BC
• [18F]CB251 PET/MR imaging probe targeting translocator protein (TSPO) independent of its Polymorphism in a Neuroinflammation Model.
  Theranostics 2020 Kim K, Kim H, Bae SH, Lee SY, Kim YH, Na J, Lee CH, Lee MS, Ko GB, Kim KY, Lee SH, Song IH, Cheon GJ, Kang KW, Kim SE, Chung JK, Kim EE, Paek SH, Lee JS, Lee BC, Youn H
• A Novel TSPO-binding Radioligand, [18F]BS224, for PET Imaging of Neuroinflammation including Less Sensitivity to TSPO Human Gene Polymorphism rs6971
  Journal of Nuclear Medicine 2020 Sanghee Lee, In Ho Song, Seok Yong Lee, Young Hwa Kim, Hye Won Youn, Byung Chul Lee and Sang Eun Kim
• Multimodal Imaging Probe Development for Pancreatic β Cells: From Fluorescence to PET.
  Journal of the American Chemical Society 2020 Kang NY, Lee JY, Lee SH, Song IH, Hwang YH, Kim MJ, Phue WH, Agrawalla BK, Wan SYD, Lalic J, Park SJ, Kim JJ, Kwon HY, Im SH, Bae MA, Ahn JH, Lim CS, Teo AKK, Park S, Kim SE, Lee BC, Lee DY, Chang YT
• Effect of PEG chain additive on 6,8-dichloro-2-phenylimidazo[1,2-a] pyridineacetamide (CB185) as a TSPO-binding ligand
  Journal of Radiopharmaceuticals and Molecular Probes 2019 Won Chang Lee, Sanghee Lee, Nunzio Denora, Valentino Laquintana, Byung Chul Lee, Sang Eun Kim
• Control of reactivity and selectivity of guanidinyliodonium salts toward 18F-Labeling by monitoring of protecting groups: Experiment and theory
  Journal of Fluorine Chemistry 2019 Keun Sam Jang, Sung-Sik Lee, Young-Ho Oh, Sanghee Lee, Sang Eun Kim, Dong Wook Kim, Byung Chul Lee, Sungyul Lee, David M. Raffel
• Cobalt-Catalyzed C-F Bond Borylation of Aryl Fluorides.
  Organic letters 2018 Lim S, Song D, Jeon S, Kim Y, Kim H, Lee S, Cho H, Lee BC, Kim SE, Kim K, Lee E
• Pd nanoparticle-silica nanotubes (Pd@SNTs) as an efficient catalyst for Suzuki–Miyaura coupling and sp2 C–H arylation in water
  Green Chemistry 2013 Ginam Park, Sanghee Lee, Sang Jun Son, Seunghoon Shin