Sandra Zakrzewska, PhD
Associate Specialist
Cardiovascular Research Inst
School of Medicine

Publications (4)

Top publication keywords:
Carrier ProteinsProtein BindingDrug Resistance, MultiplePyrococcus furiosusVoltage-Gated Sodium ChannelsRana catesbeianaProtein ConformationCalorimetryFluorescence PolarizationNeurotoxinsX-Ray DiffractionMembrane Transport ProteinsDinoflagellidaAnuraSaxitoxin

• Structural basis for saxitoxin congener binding and neutralization by anuran saxiphilins.
  Nature communications 2025 Zakrzewska S, Nixon SA, Chen Z, Hajare HS, Park ER, Mulcahy JV, Arlinghaus KM, Neu E, Konovalov K, Provasi D, Leighfield TA, Filizola M, Du Bois J, Minor DL
• Expression, purification, and characterization of anuran saxiphilins using thermofluor, fluorescence polarization, and isothermal titration calorimetry.
  STAR protocols 2023 Chen Z, Zakrzewska S, Hajare HS, Du Bois J, Minor DL
• Definition of a saxitoxin (STX) binding code enables discovery and characterization of the anuran saxiphilin family.
  Proceedings of the National Academy of Sciences of the United States of America 2022 Chen Z, Zakrzewska S, Hajare HS, Alvarez-Buylla A, Abderemane-Ali F, Bogan M, Ramirez D, O'Connell LA, Du Bois J, Minor DL
• Inward-facing conformation of a multidrug resistance MATE family transporter.
  Proceedings of the National Academy of Sciences of the United States of America 2019 Zakrzewska S, Mehdipour AR, Malviya VN, Nonaka T, Koepke J, Muenke C, Hausner W, Hummer G, Safarian S, Michel H