Samuel Goldman, MD, MPH
Professor
Medicine
School of Medicine

samuel.goldman@ucsf.edu

My work focuses on environmental risk factors for Parkinson’s disease and other neurodegenerative disorders. Among these are pesticides, solvents, smoking and traumatic brain injury, the microbiome, and the interaction of these factors with genetic susceptibility factors.

Education & Training

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  • Preventive Medicine University of California-Berkeley 05/1994
  • MPH Environmental Health Science University of California-Berkeley 05/1993
  • Internal Medicine Mt. Zion Hospital 06/1988
  • MD Medicine University of Texas, Houston 05/1987
  • BS Psychology University of Michigan 08/1982

Interests

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  • solvents
  • environmental health
  • Parkinson's disease
  • pesticides
  • epidemiology
  • environment
  • gene-environment interaction
  • traumatic brain injury

Grants and Projects

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  • Pediatric Environmental Health Specialty Unit, Western States, ATSDR, American Academy of Pediatrics, 2019-2023
  • Prevention of Hip Fractures in Patients with Parkinson?s Disease, NIA, 2018-2023
  • Integrating environmental, genomic, and functional data to characterize individual risk for Parkinson’s disease, Department of Defense, 2020-2023
  • Preventive Medicine Residencies, Health Resources and Services Administration (HRSA), 2018-2023
  • Parkinson's Disease and Exposure to Chlorinated Solvents at Marine Base Camp Lejeune, NIH, 2020-2022
  • Applying Artificial Intelligence for Early Identification of Parkinson's Disease, Michael J. Fox Foundation, 2019-2021
  • Mitochondrial DNA damage in PD and control in a pesticide-exposed cohort, Michael J. Fox Foundation, 2018-2020
  • The Parkinson?'s Registry Investigation of Diagnosis and Etiology (PRIDE) Study, Department of Defense, 2013-2019
  • Heart rate variability as a biomarker of prodromal PD, Michael J. Fox Foundation, 2016-2018
  • Parkinson's Disease Concordance and Heritability in the NAS/NRC World War II Veteran Twins Cohort, University of California-San Francisco Resource Allocation Program, 2016-2018
  • Trichloroethylene and Parkinson's Disease, NIH, 2014-2017
  • MtDNA Damage as a Biomarker for Environmental Mitochondrial Toxicity, NIEHS, 2014-2017
  • Environmental Determinants of Expressivity and Penetrance in LRRK2 Parkinsonism, Michael J. Fox Foundation, 2013-2015
  • Bay Area Solvents Study -Symptoms, Michael J. Fox Foundation, 2013-2015
  • Determinants of Penetrance & Expressivity of LRRK2 Mutations, Brin Foundation, 2009-2014

Publications (86)

Top publication keywords:
alpha-SynucleinTrichloroethyleneEnvironmentDiet, VegetarianGene-Environment InteractionParkinson DiseaseCraniocerebral TraumaDiseases in TwinsProdromal SymptomsTwins, MonozygoticTwins, DizygoticAntiparkinson AgentsOccupational ExposureFecal Microbiota TransplantationEnvironmental Exposure

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