Samuel Brusca, MD
Assistant Professor
Medicine
School of Medicine

Clinical interests: Critical care cardiologist with additional expertise in pulmonary hypertension. Focused on the management of patients with cardiogenic shock and cardiac diseases complicated by multi-organ failure. Research interests: Cardiac intensive care unit processes improvement and educational initiatives. Using peripheral biomarkers to phenotype and risk stratify patients with pulmonary hypertension and shock.

Education & Training

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• Cardiology Fellowship University of California, San Francisco 2022
• Critical Care Medicine Fellowship National Institutes of Health Clinical Center 2020
• Internal Medicine Residency Johns Hopkins Hospital 2017
• MD New York University School of Medicine 2014
• BS Neuroscience Washington and Lee University 2010

Interests

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• Pulmonary Hypertension
• Shock
• Cardiac Critical Care

Publications (16)

Top publication keywords:
Critical CareMicrobiotaIntensive Care UnitsHeart-Assist DevicesPulmonary ArteryBerylliumLung DiseasesEducation, Medical, GraduateCell-Free Nucleic AcidsCardiovascular DiseasesShock, CardiogenicCardiologistsCertificationHypertension, PulmonaryClinical Competence

• Balancing the scales of adversity: a socioecological approach to reducing the global burden of stroke and cardiovascular disease.
  The Lancet. Neurology 2023 Brusca SB, Albert MA
• Management of Cardiogenic Shock Unrelated to Acute Myocardial Infarction.
  The Canadian journal of cardiology 2023 Barnett CF, Brusca SB, Hanff TC, Blumer V, Kalif A, Kanwar M
• Outcomes of Patients With Primary Cardiac Diagnoses Admitted to Cardiac vs Noncardiac Intensive Care Units.
  JACC advances 2022 Brusca SB, Galiatsatos P, Warner S, Li X, Powell-Wiley TM, Kadri SS, Solomon MA
• Oxygen Supplementation and Hyperoxia in Critically Ill Cardiac Patients: From Pathophysiology to Clinical Practice.
  JACC. Advances 2022 Thomas A, van Diepen S, Beekman R, Sinha SS, Brusca SB, Alviar CL, Jentzer J, Bohula EA, Katz JN, Shahu A, Barnett C, Morrow DA, Gilmore EJ, Solomon MA, Miller PE
• Plasma Cell-Free DNA Predicts Survival and Maps Specific Sources of Injury in Pulmonary Arterial Hypertension.
  Circulation 2022 Brusca SB, Elinoff JM, Zou Y, Jang MK, Kong H, Demirkale CY, Sun J, Seifuddin F, Pirooznia M, Valantine HA, Tanba C, Chaturvedi A, Graninger GM, Harper B, Chen LY, Cole J, Kanwar M, Benza RL, Preston …

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• The shock team: a multidisciplinary approach to early patient phenotyping and appropriate care escalation in cardiogenic shock.
  Current opinion in cardiology 2022 Brusca SB, Caughron H, Njoroge JN, Cheng R, O'Brien CG, Barnett CF
• Forming the Hematology-Oncology Collaborative Videoconferencing (CO-VID) Learning Initiative: Experiential Lessons Learned From a Novel Trainee-Led Multidisciplinary Virtual Learning Platform.
  JCO oncology practice 2021 Martin RL, Grant MJ, Kimani S, Midha S, May J, Patell R, Collier E, Furfaro D, Bodine C, Reap L, Shah N, DeLaune J, Brusca S, Olazagasti C, Goyal S, Rubinstein S, Hakim N, Qin S, Browning SL, Sena L, …
• Pulmonary arterial hypertension patients display normal kinetics of clot formation using thrombelastography.
  Pulmonary circulation 2021 Lu M, Blaine KP, Cullinane A, Hall C, Dulau-Florea A, Sun J, Chenwi HF, Graninger GM, Harper B, Thompson K, Krack J, Barnett CF, Brusca SB, Elinoff JM, Solomon MA
• Contemporary Management of Severe Acute Kidney Injury and Refractory Cardiorenal Syndrome: JACC Council Perspectives.
  Journal of the American College of Cardiology 2020 Jentzer JC, Bihorac A, Brusca SB, Del Rio-Pertuz G, Kashani K, Kazory A, Kellum JA, Mao M, Moriyama B, Morrow DA, Patel HN, Rali AS, van Diepen S, Solomon MA, Critical Care Cardiology Working Group of…
• How low should we go? Potential benefits and ramifications of the pulmonary hypertension hemodynamic definitions proposed by the 6th World Symposium.
  Current opinion in pulmonary medicine 2020 Brusca SB, Zou Y, Elinoff JM
• COVID-19 and Disruptive Modifications to Cardiac Critical Care Delivery: JACC Review Topic of the Week.
  Journal of the American College of Cardiology 2020 Katz JN, Sinha SS, Alviar CL, Dudzinski DM, Gage A, Brusca SB, Flanagan MC, Welch T, Geller BJ, Miller PE, Leonardi S, Bohula EA, Price S, Chaudhry SP, Metkus TS, O'Brien CG, Sionis A, Barnett CF, …
• Role of Critical Care Medicine Training in the Cardiovascular Intensive Care Unit: Survey Responses From Dual Certified Critical Care Cardiologists.
  Journal of the American Heart Association 2019 Brusca SB, Barnett C, Barnhart BJ, Weng W, Morrow DA, Soble JS, Katz JN, Wiley BM, van Diepen S, Gomez AD, Solomon MA
• Environment, Epigenetics, and Differential Responses to Beryllium Exposure: Are We There Yet?
  American journal of respiratory cell and molecular biology 2019 Brusca S, Agbor-Enoh S
• Use of thermodilution cardiac output overestimates diagnoses of exercise-induced pulmonary hypertension.
  Pulmonary circulation 2017 Hsu S, Brusca SB, Rhodes PS, Kolb TM, Mathai SC, Tedford RJ
• Decreased bacterial diversity characterizes the altered gut microbiota in patients with psoriatic arthritis, resembling dysbiosis in inflammatory bowel disease.
  Arthritis & rheumatology (Hoboken, N.J.) 2015 Scher JU, Ubeda C, Artacho A, Attur M, Isaac S, Reddy SM, Marmon S, Neimann A, Brusca S, Patel T, Manasson J, Pamer EG, Littman DR, Abramson SB
• Microbiome and mucosal inflammation as extra-articular triggers for rheumatoid arthritis and autoimmunity.
  Current opinion in rheumatology 2014 Brusca SB, Abramson SB, Scher JU