Sabine Mueller, MD, PhD, MAS
Professor
Neurology
School of Medicine

Education & Training

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• M.D. School of Medicine Universitat Hamburg 2005

Websites

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• Clinical Profile at UCSF Benioff Children's Hospital (ucsfbenioffchildrens.org)

Publications (195)

Top publication keywords:
AstrocytomaGliomaHistonesOncolytic VirusesCranial IrradiationEverolimusMedulloblastomaBrain NeoplasmsCerebellar NeoplasmsMeasles virusBrain Stem NeoplasmsCentral Nervous System NeoplasmsOncolytic VirotherapyCirculating Tumor DNAChild

• Salvage therapies for first relapse of SHH medulloblastoma in early childhood.
  Neuro-oncology 2025 Erker C, Mynarek M, Simbozel M, Craig BT, Harrod VL, Cappellano AM, Cohen KJ, Lopez VS, Morales La Madrid A, Cacciotti C, Baroni L, Salloum R, Margol AS, Michaiel G, Aguilera D, Mazewski CM, Kline CN,…
• Germline analysis of an international cohort of pediatric diffuse midline glioma patients.
  Neuro-oncology 2025 Mateos MK, Ajuyah P, Fuentes-Bolanos N, El-Kamand S, Barahona P, Altekoester AK, Mayoh C, Holliday H, Liu J, Cui L, Pfaff E, Mackay A, Resnick AC, Pinese M, Lau LMS, Khuong-Quang DA, Dias K, Goudie C,…
• Measles Oncolytic Virus as an Immunotherapy for Recurrent/Refractory Pediatric Medulloblastoma and Atypical Teratoid/Rhabdoid Tumor: Results from PNOC005.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2025 Yu B, Kline C, Hoare O, Jung J, Knowles T, Ranavaya A, Minturn J, Banerjee A, Leary S, Crotty E, Abdelbaki M, Whipple N, Goldman S, Margol A, Bhatia A, Dababo N, George E, Nabavizadeh A, Pampaloni MH,…
• Imaging Clusters of Pediatric Low-Grade Glioma Are Associated with Distinct Molecular Characteristics.
  AJNR. American journal of neuroradiology 2025 Fathi Kazerooni A, Kraya A, Rathi KS, Kim MC, Kesherwani V, Corbett R, Vossough A, Khalili N, Gandhi D, Khalili N, Familiar AM, Jin R, Huang X, Zhu Y, Sickler A, Lueder MR, Phul S, Storm PB, Ware JB, …
• Applications of artificial intelligence and advanced imaging in pediatric diffuse midline glioma.
  Neuro-oncology 2025 Haddadi Avval A, Banerjee S, Zielke J, Kann BH, Mueller S, Rauschecker AM

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• Author Correction: The type II RAF inhibitor tovorafenib in relapsed/refractory pediatric low-grade glioma: the phase 2 FIREFLY-1 trial.
  Nature medicine 2025 Kilburn LB, Khuong-Quang DA, Hansford JR, Landi D, van der Lugt J, Leary SES, Driever PH, Bailey S, Perreault S, McCowage G, Waanders AJ, Ziegler DS, Witt O, Baxter PA, Kang HJ, Hassall TE, Han JW, …
• Deep learning volumetrics reveal distinct clinical trajectories for pediatric low-grade gliomas under surveillance: A multicenter study.
  Neuro-oncology advances 2025 Climent Pardo JC, Zapaishchykova A, Boyd A, Tak D, Zielke J, Mahootiha M, Ye Z, Vajapeyam S, Jones J, Smith C, Familiar AM, Nabavizadeh A, Bandopadhayay P, Mueller S, Aerts HJWL, Haas-Kogan DA, Michor…
• Dual treatment with Val-083 and AZD1775 shows potent anti-tumor activity in diffuse midline glioma models.
  NPJ precision oncology 2025 Subramaniam B, Roy D, Woldegerima A, Chong WC, Przystal JM, Zhang J, Laternser S, Kritzer B, Rangnath S, Knowles T, Yadavilli S, Packer R, Mueller S, Nazarian J
• Genetic ancestry superpopulations show distinct prevalence and outcomes across pediatric central nervous system tumors from the Pediatric Brain Tumor Atlas and Pediatric Neuro-Oncology Consortium.
  Neuro-oncology 2025 Corbett RJ, Gullickson CC, Geng Z, Brown MA, Zhang B, Zhong C, Van Kuren N, Chroni A, Blackden C, Naqvi AS, Plisiewicz A, McHugh S, Drake E, Lehmann K, Davidson TB, Prados M, Storm PB, Resnick AC, …
• cIMPACT-NOW update 10: Recommendations for defining new types for central nervous system tumor classification.
  Brain pathology (Zurich, Switzerland) 2025 Hawkins C, Aldape K, Capper D, von Deimling A, Giannini C, Gilbert MR, Jacques TS, Jones D, Komori T, Louis DN, Mueller S, Nasrallah M, Orr BA, Perry A, Pfister SM, Sahm F, Sarkar C, Snuderl M, …
• PNOC009: Convection-enhanced delivery of liposomal irinotecan in patients with newly diagnosed diffuse intrinsic pontine glioma.
  Neuro-oncology advances 2025 Mueller S, Kline C, Lu AY, Hoogendijk R, Wembacher-Schroeder E, Banerjee A, Reddy AT, Raber S, Hoffman C, Stoller S, Prados M, Molinaro A, Gupta N
• Longitudinal Risk Prediction for Pediatric Glioma with Temporal Deep Learning.
  NEJM AI 2025 Tak D, Garomsa BA, Zapaishchykova A, Ye Z, Vajapeyam S, Mahootiha M, Pardo JCC, Smith C, Familiar AM, Chaunzwa TL, Liu KX, Prabhu SP, Bandopadhayay P, Nabavizadeh A, Mueller S, Aerts HJWL, Haas-Kogan …
• Gross tumor volume increase and need for adaptive radiotherapy in pediatric-type diffuse high-grade glioma of the midline structures.
  Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2025 van Ommen F, van Genechten T, Willemsen-Bosman ME, Peters M, Seravalli E, van der Lugt J, Nievelstein RAJ, Mueller S, Hulleman E, van Vuurden DG, Kranendonk MEG, Hoving EW, Hoeben BAW, Janssens GO
• Effective targeting of PDGFRA-altered high-grade glioma with avapritinib.
  Cancer cell 2025 Mayr L, Neyazi S, Schwark K, Trissal M, Beck A, Labelle J, Eder SK, Weiler-Wichtl L, Marques JG, de Biagi-Junior CAO, Lo Cascio C, Chapman O, Sridhar S, Kenkre R, Dutta A, Wang S, Wang J, Hack O, …
• Current clinical trials for craniopharyngiomas: what's on the horizon?
  Journal of neuro-oncology 2025 Joshi N, Mueller S, Kline C
• Correction: Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways.
  Cancer discovery 2025 Venneti S, Kawakibi AR, Ji S, Waszak SM, Sweha SR, Mota M, Pun M, Deogharkar A, Chung C, Tarapore RS, Ramage S, Chi A, Wen PY, Arrillaga-Romany I, Batchelor TT, Butowski NA, Sumrall A, Shonka N, …
• Clinical Characteristics and Outcomes of Central Nervous System Tumors Harboring NTRK Gene Fusions.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2025 Lamoureux AA, Fisher MJ, Lemelle L, Pfaff E, Amir-Yazdani P, Kramm C, De Wilde B, Kazanowska B, Hutter C, Pfister SM, Sturm D, Jones DTW, Orbach D, Pierron G, Raskin S, Drilon A, Diamond EL, Harada G,…
• Paediatric strategy forum for medicinal product development in diffuse midline gliomas in children and adolescents ACCELERATE in collaboration with the European Medicines Agency with participation of the Food and Drug Administration.
  European journal of cancer (Oxford, England : 1990) 2025 Pearson AD, Mueller S, Filbin MG, Grill J, Hawkins C, Jones C, Donoghue M, Drezner N, Weiner S, Russo M, Dun MD, Allen JE, Alonso M, Benaim E, Buenger V, de Rojas T, Desserich K, Fox E, Friend J, …
• Multimodal deep learning improves recurrence risk prediction in pediatric low-grade gliomas.
  Neuro-oncology 2025 Mahootiha M, Tak D, Ye Z, Zapaishchykova A, Likitlersuang J, Climent Pardo JC, Boyd A, Vajapeyam S, Chopra R, Prabhu SP, Liu KX, Elhalawani H, Nabavizadeh A, Familiar A, Mueller S, Aerts HJWL, …
• cIMPACT-NOW update 9: Recommendations on utilization of genome-wide DNA methylation profiling for central nervous system tumor diagnostics.
  Neuro-oncology advances 2025 Aldape K, Capper D, von Deimling A, Giannini C, Gilbert MR, Hawkins C, Hench J, Jacques TS, Jones D, Louis DN, Mueller S, Orr BA, Nasrallah M, Pfister SM, Sahm F, Snuderl M, Solomon D, Varlet P, …
• Multiparametric MRI along with machine learning predicts prognosis and treatment response in pediatric low-grade glioma.
  Nature communications 2025 Fathi Kazerooni A, Kraya A, Rathi KS, Kim MC, Vossough A, Khalili N, Familiar AM, Gandhi D, Khalili N, Kesherwani V, Haldar D, Anderson H, Jin R, Mahtabfar A, Bagheri S, Guo Y, Li Q, Huang X, Zhu Y, …
• Omnigene-Guttm ensures fecal microbiome stability in the pediatric population.
  AMB Express 2024 Hoogendijk R, van den Broek TJM, Lee H, Mueller S, Kline C, Bianco J, Top J, de Zoete MR, Kester L, Calkoen F, van der Lugt J
• A foundation model for generalized brain MRI analysis.
  medRxiv : the preprint server for health sciences 2024 Tak D, Garomsa BA, Chaunzwa TL, Zapaishchykova A, Climent Pardo JC, Ye Z, Zielke J, Ravipati Y, Vajapeyam S, Mahootiha M, Smith C, Familiar AM, Liu KX, Prabhu S, Bandopadhayay P, Nabavizadeh A, …
• Editor's Note: BRAF Status in Personalizing Treatment Approaches for Pediatric Gliomas.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2024 Olow A, Mueller S, Yang X, Hashizume R, Meyerowitz J, Weiss W, Resnick AC, Waanders AJ, Stalpers LJA, Berger MS, Gupta N, James CD, Petritsch CK, Haas-Kogan DA
• Retrospective Comparison of Targeted Anticancer Drugs Predicted by the CNS-TAP Tool Versus Those Selected by a Molecularly Driven Tumor Board in Children With DIPG.
  Journal of pediatric hematology/oncology 2024 Roberts HJ, Ravi K, Marini BL, Schepers A, Kline C, Kilburn L, Prados M, Byron SA, Sturza J, Mueller S, Koschmann C, Franson AT
• Towards consistency in pediatric brain tumor measurements: Challenges, solutions, and the role of artificial intelligence-based segmentation.
  Neuro-oncology 2024 Familiar AM, Fathi Kazerooni A, Vossough A, Ware JB, Bagheri S, Khalili N, Anderson H, Haldar D, Storm PB, Resnick AC, Kann BH, Aboian M, Kline C, Weller M, Huang RY, Chang SM, Fangusaro JR, Hoffman …
• Resistance, rebound, and recurrence regrowth patterns in pediatric low-grade glioma treated by MAPK inhibition: A modified Delphi approach to build international consensus-based definitions-International Pediatric Low-Grade Glioma Coalition.
  Neuro-oncology 2024 O'Hare P, Cooney T, de Blank P, Gutmann DH, Kieran M, Milde T, Fangusaro J, Fisher M, Avula S, Packer R, Fukuoka K, Mankad K, Mueller S, Waanders AJ, Opocher E, Bouffet E, Raabe E, Werle NE, Azizi AA,…
• The oncolytic adenovirus Delta-24-RGD in combination with ONC201 induces a potent antitumor response in pediatric high-grade and diffuse midline glioma models.
  Neuro-oncology 2024 de la Nava D, Ausejo-Mauleon I, Laspidea V, Gonzalez-Huarriz M, Lacalle A, Casares N, Zalacain M, Marrodan L, García-Moure M, Ochoa MC, Tallon-Cobos AC, Hernandez-Osuna R, Marco-Sanz J, Dhandapani L, …
• Marrow-ablative consolidation chemotherapy and molecular targeted therapy delivered in a risk-adapted manner for newly diagnosed children with choroid plexus carcinoma: A work in progress.
  Neuro-oncology advances 2024 Yankelevich M, Zaky W, Lafay-Cousin L, Osorio D, Adamski J, Kordes U, Finlay JL, Prados M, Mueller S
• Stepwise Transfer Learning for Expert-level Pediatric Brain Tumor MRI Segmentation in a Limited Data Scenario.
  Radiology. Artificial intelligence 2024 Boyd A, Ye Z, Prabhu SP, Tjong MC, Zha Y, Zapaishchykova A, Vajapeyam S, Catalano PJ, Hayat H, Chopra R, Liu KX, Nabavizadeh A, Resnick AC, Mueller S, Haas-Kogan DA, Aerts HJWL, Poussaint TY, Kann BH
• Longitudinal risk prediction for pediatric glioma with temporal deep learning.
  medRxiv : the preprint server for health sciences 2024 Tak D, Garomsa BA, Zapaishchykova A, Ye Z, Vajapeyam S, Mahootiha M, Climent Pardo JC, Smith C, Familiar AM, Chaunzwa T, Liu KX, Prabhu S, Bandopadhayay P, Nabavizadeh A, Mueller S, Aerts HJ, Haas-…
• A Standardized Nomenclature Design for Systematic Referencing and Identification of Animal Cellular Material.
  Animals : an open access journal from MDPI 2024 Schrade L, Mah N, Bandrowski A, Chen Y, Dewender J, Diecke S, Hiepen C, Lancaster MA, Marques-Bonet T, Martinez S, Mueller SC, Navara C, Prigione A, Seltmann S, Sochacki J, Sutcliffe MA, Zywitza V, …
• A review of current therapeutics targeting the mitochondrial protease ClpP in diffuse midline glioma, H3 K27-altered.
  Neuro-oncology 2024 Jackson ER, Persson ML, Fish CJ, Findlay IJ, Mueller S, Nazarian J, Hulleman E, van der Lugt J, Duchatel RJ, Dun MD
• ACTION: a randomized phase 3 study of ONC201 (dordaviprone) in patients with newly diagnosed H3 K27M-mutant diffuse glioma.
  Neuro-oncology 2024 Arrillaga-Romany I, Lassman A, McGovern SL, Mueller S, Nabors B, van den Bent M, Vogelbaum MA, Allen JE, Melemed AS, Tarapore RS, Wen PY, Cloughesy T
• Rational combination platform trial design for children and young adults with diffuse midline glioma: A report from PNOC.
  Neuro-oncology 2024 Mueller S, Kline C, Franson A, van der Lugt J, Prados M, Waszak SM, Plasschaert SLA, Molinaro AM, Koschmann C, Nazarian J
• Safety and pharmacokinetics of ONC201 (dordaviprone) administered two consecutive days per week in pediatric patients with H3 K27M-mutant glioma.
  Neuro-oncology 2024 Odia Y, Koschmann C, Vitanza NA, de Blank P, Aguilera D, Allen J, Daghistani D, Hall M, Khatib Z, Kline C, MacDonald T, Mueller S, Faison SL, Allen JE, Naderer OJ, Ramage SC, Tarapore RS, McGovern SL,…
• Author Correction: The type II RAF inhibitor tovorafenib in relapsed/refractory pediatric low-grade glioma: the phase 2 FIREFLY-1 trial.
  Nature medicine 2024 Kilburn LB, Khuong-Quang DA, Hansford JR, Landi D, van der Lugt J, Leary SES, Driever PH, Bailey S, Perreault S, McCowage G, Waanders AJ, Ziegler DS, Witt O, Baxter PA, Kang HJ, Hassall TE, Han JW, …
• Noninvasive Molecular Subtyping of Pediatric Low-Grade Glioma with Self-Supervised Transfer Learning.
  Radiology. Artificial intelligence 2024 Tak D, Ye Z, Zapaischykova A, Zha Y, Boyd A, Vajapeyam S, Chopra R, Hayat H, Prabhu SP, Liu KX, Elhalawani H, Nabavizadeh A, Familiar A, Resnick AC, Mueller S, Aerts HJWL, Bandopadhayay P, Ligon KL, …
• RNA aggregates harness the danger response for potent cancer immunotherapy.
  Cell 2024 Mendez-Gomez HR, DeVries A, Castillo P, von Roemeling C, Qdaisat S, Stover BD, Xie C, Weidert F, Zhao C, Moor R, Liu R, Soni D, Ogando-Rivas E, Chardon-Robles J, McGuiness J, Zhang D, Chung MC, …
• Comparison of Volumetric and 2D Measurements and Longitudinal Trajectories in the Response Assessment of BRAF V600E-Mutant Pediatric Gliomas in the Pacific Pediatric Neuro-Oncology Consortium Clinical Trial.
  AJNR. American journal of neuroradiology 2024 Ramakrishnan D, Brüningk SC, von Reppert M, Memon F, Maleki N, Aneja S, Kazerooni AF, Nabavizadeh A, Lin M, Bousabarah K, Molinaro A, Nicolaides T, Prados M, Mueller S, Aboian MS
• Diffusion deep learning for brain age prediction and longitudinal tracking in children through adulthood.
  Imaging neuroscience (Cambridge, Mass.) 2024 Zapaishchykova A, Tak D, Ye Z, Liu KX, Likitlersuang J, Vajapeyam S, Chopra RB, Seidlitz J, Bethlehem RAI, Mak RH, Mueller S, Haas-Kogan DA, Poussaint TY, Aerts HJWL, Kann BH
• Consensus framework for conducting phase I/II clinical trials for children, adolescents, and young adults with pediatric low-grade glioma: Guidelines established by the International Pediatric Low-Grade Glioma Coalition Clinical Trial Working Group.
  Neuro-oncology 2024 Mueller S, Fangusaro J, Thomas AO, Jacques TS, Bandopadhayay P, de Blank P, Packer RJ, Fouladi M, van Meeteren AS, Jones D, Perry A, Nakano Y, Hargrave D, Riedl D, Robison NJ, Partanen M, Fisher MJ, …
• PI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma.
  The Journal of clinical investigation 2024 Duchatel RJ, Jackson ER, Parackal SG, Kiltschewskij D, Findlay IJ, Mannan A, Staudt DE, Thomas BC, Germon ZP, Laternser S, Kearney PS, Jamaluddin MFB, Douglas AM, Beitaki T, McEwen HP, Persson ML, …
• The Landscape of US and Global Rare Tumor Research Programs: A Systematic Review.
  The oncologist 2024 Vivelo C, Reilly KM, Widemann BC, Wedekind MF, Painter C, O'Neill AF, Mueller S, Elemento O, Gross AM, Sandler AB
• Pediatric low-grade glioma: State-of-the-art and ongoing challenges.
  Neuro-oncology 2024 Fangusaro J, Jones DT, Packer RJ, Gutmann DH, Milde T, Witt O, Mueller S, Fisher MJ, Hansford JR, Tabori U, Hargrave D, Bandopadhayay P
• Comparison of volumetric and 2D-based response methods in the PNOC-001 pediatric low-grade glioma clinical trial.
  Neuro-oncology advances 2023 von Reppert M, Ramakrishnan D, Brüningk SC, Memon F, Abi Fadel S, Maleki N, Bahar R, Avesta AE, Jekel L, Sala M, Lost J, Tillmanns N, Kaur M, Aneja S, Fathi Kazerooni A, Nabavizadeh A, Lin M, Hoffmann…
• Clinical outcome of pediatric medulloblastoma patients with Li-Fraumeni syndrome.
  Neuro-oncology 2023 Kolodziejczak AS, Guerrini-Rousseau L, Planchon JM, Ecker J, Selt F, Mynarek M, Obrecht D, Sill M, Autry RJ, Stutheit-Zhao E, Hirsch S, Amouyal E, Dufour C, Ayrault O, Torrejon J, Waszak SM, Ramaswamy…
• A road map for the treatment of pediatric diffuse midline glioma.
  Cancer cell 2023 Koschmann C, Al-Holou WN, Alonso MM, Anastas J, Bandopadhayay P, Barron T, Becher O, Cartaxo R, Castro MG, Chung C, Clausen M, Dang D, Doherty R, Duchatel R, Dun M, Filbin M, Franson A, Galban S, …
• Noninvasive molecular subtyping of pediatric low-grade glioma with self-supervised transfer learning.
  medRxiv : the preprint server for health sciences 2023 Tak D, Ye Z, Zapaishchykova A, Zha Y, Boyd A, Vajapeyam S, Chopra R, Hayat H, Prabhu S, Liu KX, Elhalawani H, Nabavizadeh A, Familiar A, Resnick A, Mueller S, Aerts HJWL, Bandopadhayay P, Ligon K, …
• Everolimus for Children With Recurrent or Progressive Low-Grade Glioma: Results From the Phase II PNOC001 Trial.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2023 Haas-Kogan DA, Aboian MS, Minturn JE, Leary SES, Abdelbaki MS, Goldman S, Elster JD, Kraya A, Lueder MR, Ramakrishnan D, von Reppert M, Liu KX, Rokita JL, Resnick AC, Solomon DA, Phillips JJ, Prados M…
• The type II RAF inhibitor tovorafenib in relapsed/refractory pediatric low-grade glioma: the phase 2 FIREFLY-1 trial.
  Nature medicine 2023 Kilburn LB, Khuong-Quang DA, Hansford JR, Landi D, van der Lugt J, Leary SES, Driever PH, Bailey S, Perreault S, McCowage G, Waanders AJ, Ziegler DS, Witt O, Baxter PA, Kang HJ, Hassall TE, Han JW, …
• Automated temporalis muscle quantification and growth charts for children through adulthood.
  Nature communications 2023 Zapaishchykova A, Liu KX, Saraf A, Ye Z, Catalano PJ, Benitez V, Ravipati Y, Jain A, Huang J, Hayat H, Likitlersuang J, Vajapeyam S, Chopra RB, Familiar AM, Nabavidazeh A, Mak RH, Resnick AC, Mueller …
• PNOC015: Repeated convection-enhanced delivery of MTX110 (aqueous panobinostat) in children with newly diagnosed diffuse intrinsic pontine glioma.
  Neuro-oncology 2023 Mueller S, Kline C, Stoller S, Lundy S, Christopher L, Reddy AT, Banerjee A, Cooney TM, Raber S, Hoffman C, Luks T, Wembacher-Schroeder E, Lummel N, Zhang Y, Bonner ER, Nazarian J, Molinaro AM, Prados…
• Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways.
  Cancer discovery 2023 Venneti S, Kawakibi AR, Ji S, Waszak SM, Sweha SR, Mota M, Pun M, Deogharkar A, Chung C, Tarapore RS, Ramage S, Chi A, Wen PY, Arrillaga-Romany I, Batchelor TT, Butowski NA, Sumrall A, Shonka N, …
• TIM-3 blockade in diffuse intrinsic pontine glioma models promotes tumor regression and antitumor immune memory.
  Cancer cell 2023 Ausejo-Mauleon I, Labiano S, de la Nava D, Laspidea V, Zalacain M, Marrodán L, García-Moure M, González-Huarriz M, Hervás-Corpión I, Dhandapani L, Vicent S, Collantes M, Peñuelas I, Becher OJ, Filbin …
• A multi-institutional pediatric dataset of clinical radiology MRIs by the Children's Brain Tumor Network.
  ArXiv 2023 Familiar AM, Kazerooni AF, Anderson H, Lubneuski A, Viswanathan K, Breslow R, Khalili N, Bagheri S, Haldar D, Kim MC, Arif S, Madhogarhia R, Nguyen TQ, Frenkel EA, Helili Z, Harrison J, Farahani K, …
• Expert-level pediatric brain tumor segmentation in a limited data scenario with stepwise transfer learning.
  medRxiv : the preprint server for health sciences 2023 Boyd A, Ye Z, Prabhu S, Tjong MC, Zha Y, Zapaishchykova A, Vajapeyam S, Hayat H, Chopra R, Liu KX, Nabavidazeh A, Resnick A, Mueller S, Haas-Kogan D, Aerts HJWL, Poussaint T, Kann BH
• Evolution and implementation of radiographic response criteria in neuro-oncology.
  Neuro-oncology advances 2023 Ramakrishnan D, von Reppert M, Krycia M, Sala M, Mueller S, Aneja S, Nabavizadeh A, Galldiks N, Lohmann P, Raji C, Ikuta I, Memon F, Weinberg BD, Aboian MS
• Pan-cancer atlas of somatic core and linker histone mutations.
  NPJ genomic medicine 2023 Bonner ER, Dawood A, Gordish-Dressman H, Eze A, Bhattacharya S, Yadavilli S, Mueller S, Waszak SM, Nazarian J
• OpenPBTA: The Open Pediatric Brain Tumor Atlas.
  Cell genomics 2023 Shapiro JA, Gaonkar KS, Spielman SJ, Savonen CL, Bethell CJ, Jin R, Rathi KS, Zhu Y, Egolf LE, Farrow BK, Miller DP, Yang Y, Koganti T, Noureen N, Koptyra MP, Duong N, Santi M, Kim J, Robins S, Storm …
• Translational considerations for immunotherapy clinical trials in pediatric neuro-oncology.
  Neoplasia (New York, N.Y.) 2023 Foster JB, Alonso MM, Sayour E, Davidson TB, Persson ML, Dun MD, Kline C, Mueller S, Vitanza NA, van der Lugt J
• ONC201 in Combination with Paxalisib for the Treatment of H3K27-Altered Diffuse Midline Glioma.
  Cancer research 2023 Jackson ER, Duchatel RJ, Staudt DE, Persson ML, Mannan A, Yadavilli S, Parackal S, Game S, Chong WC, Jayasekara WSN, Grand ML, Kearney PS, Douglas AM, Findlay IJ, Germon ZP, McEwen HP, Beitaki TS, …
• Cellular Therapy for Children with Central Nervous System Tumors: Mining and Mapping the Correlative Data.
  Current oncology reports 2023 Crotty EE, Wilson AL, Davidson T, Tahiri S, Gust J, Griesinger AM, Venkataraman S, Park JR, Mueller S, Rood BR, Hwang EI, Wang LD, Vitanza NA
• ONC201 in combination with paxalisib for the treatment of H3K27-altered diffuse midline glioma.
  Cancer research 2023 Jackson ER, Duchatel RJ, Staudt DE, Persson ML, Mannan A, Yadavilli S, Parackal S, Game S, Chong WC, Jayasekara WSN, Le Grand M, Kearney PS, Douglas AM, Findlay IJ, Germon ZP, McEwen HP, Beitaki TS, …
• Precision based approach to tailoring radiotherapy in the multidisciplinary management of pediatric central nervous system tumors.
  Journal of the National Cancer Center 2023 Phuong C, Qiu B, Mueller S, Braunstein SE
• Evaluating preclinical evidence for clinical translation in childhood brain tumours: Guidelines from the CONNECT, PNOC, and ITCC brain networks.
  Frontiers in oncology 2023 Jones C, Straathof K, Fouladi M, Hargrave D, Prados M, Resnick A, Doz F, Jones DTW, Mueller S
• Correspondence on 'H3.3K27M mutation is not a suitable target for immunotherapy in HLA-A2+ patients with diffuse midline glioma' by Immisch et al.
  Journal for immunotherapy of cancer 2023 Chheda ZS, Mueller S, Hegde B, Yamamichi A, Butterfield LH, Okada H
• Indigenous peoples and inclusion in clinical and genomic research: Understanding the history and navigating contemporary engagement.
  Neoplasia (New York, N.Y.) 2023 Waanders A, Brown A, Caron NR, Plisiewicz A, McHugh ST, Nguyen TQ, Lehmann K, Stevens J, Storm PJ, Resnick A, Davidson TB, Mueller S, Kline C
• Past, present and future of Focused Ultrasound as an adjunct or complement to DIPG/DMG therapy: A consensus of the 2021 FUSF DIPG meeting.
  Neoplasia (New York, N.Y.) 2023 Parekh K, LeBlang S, Nazarian J, Mueller S, Zacharoulis S, Hynynen K, Powlovich L
• Retrospective dataset and survey analyses identify gaps in data collection for craniopharyngioma and priorities of patients and families affected by the disease.
  Neoplasia (New York, N.Y.) 2023 Marshall E, Joshi N, Crowley J, McCormack S, Cheng S, Faig W, Storm PB, Resnick A, Mueller S, Malbari F, Kline C
• Advances and Clinical Trials Update in the Treatment of Diffuse Intrinsic Pontine Gliomas.
  Pediatric neurosurgery 2023 Dalle Ore C, Coleman C, Gupta N, Mueller S
• Response and resistance to BRAFV600E inhibition in gliomas: Roadblocks ahead?
  Frontiers in oncology 2023 Capogiri M, De Micheli AJ, Lassaletta A, Muñoz DP, Coppé JP, Mueller S, Guerreiro Stucklin AS
• Pediatric low-grade glioma: Targeted therapeutics and clinical trials in the molecular era.
  Neoplasia (New York, N.Y.) 2022 Manoharan N, Liu KX, Mueller S, Haas-Kogan DA, Bandopadhayay P
• Outcomes of Infants and Young Children With Relapsed Medulloblastoma After Initial Craniospinal Irradiation-Sparing Approaches: An International Cohort Study.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2022 Erker C, Mynarek M, Bailey S, Mazewski CM, Baroni L, Massimino M, Hukin J, Aguilera D, Cappellano AM, Ramaswamy V, Lassaletta A, Perreault S, Kline CN, Rajagopal R, Michaiel G, Zapotocky M, Santa-…
• Interdisciplinary care of children with diffuse midline glioma.
  Neoplasia (New York, N.Y.) 2022 Coleman C, Chen K, Lu A, Seashore E, Stoller S, Davis T, Braunstein S, Gupta N, Mueller S
• The children's brain tumor network (CBTN) - Accelerating research in pediatric central nervous system tumors through collaboration and open science.
  Neoplasia (New York, N.Y.) 2022 Lilly JV, Rokita JL, Mason JL, Patton T, Stefankiewiz S, Higgins D, Trooskin G, Larouci CA, Arya K, Appert E, Heath AP, Zhu Y, Brown MA, Zhang B, Farrow BK, Robins S, Morgan AM, Nguyen TQ, Frenkel E, …
• Real-time drug testing of paediatric diffuse midline glioma to support clinical decision making: The Zurich DIPG/DMG centre experience.
  European journal of cancer (Oxford, England : 1990) 2022 Mueller T, Laternser S, Guerreiro Stücklin AS, Gerber NU, Mourabit S, Rizo M, Rushing EJ, Kottke R, Grotzer M, Krayenbühl N, Nazarian J, Mueller S
• Upfront Biology-Guided Therapy in Diffuse Intrinsic Pontine Glioma: Therapeutic, Molecular, and Biomarker Outcomes from PNOC003.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2022 Kline C, Jain P, Kilburn L, Bonner ER, Gupta N, Crawford JR, Banerjee A, Packer RJ, Villanueva-Meyer J, Luks T, Zhang Y, Kambhampati M, Zhang J, Yadavilli S, Zhang B, Gaonkar KS, Rokita JL, Kraya A, …
• Phase I dose escalation and expansion trial of single agent ONC201 in pediatric diffuse midline gliomas following radiotherapy.
  Neuro-oncology advances 2022 Gardner SL, Tarapore RS, Allen J, McGovern SL, Zaky W, Odia Y, Daghistani D, Diaz Z, Hall MD, Khatib Z, Koschmann C, Cantor E, Kurokawa R, MacDonald TJ, Aguilera D, Vitanza NA, Mueller S, Kline C, Lu …
• Functional network alterations in young brain tumor patients with radiotherapy-induced memory impairments and vascular injury.
  Frontiers in neurology 2022 Morrison MA, Walter S, Mueller S, Felton E, Jakary A, Stoller S, Molinaro AM, Braunstein SE, Hess CP, Lupo JM
• Circulating tumor DNA sequencing provides comprehensive mutation profiling for pediatric central nervous system tumors.
  NPJ precision oncology 2022 Bonner ER, Harrington R, Eze A, Bornhorst M, Kline CN, Gordish-Dressman H, Dawood A, Das B, Chen L, Pauly R, Williams PM, Karlovich C, Peach A, Howell D, Doroshow J, Kilburn L, Packer RJ, Mueller S, …
• Imipridones affect tumor bioenergetics and promote cell lineage differentiation in diffuse midline gliomas.
  Neuro-oncology 2022 Przystal JM, Cianciolo Cosentino C, Yadavilli S, Zhang J, Laternser S, Bonner ER, Prasad R, Dawood AA, Lobeto N, Chin Chong W, Biery MC, Myers C, Olson JM, Panditharatna E, Kritzer B, Mourabit S, …
• Multiplatform molecular analyses refine classification of gliomas arising in patients with neurofibromatosis type 1.
  Acta neuropathologica 2022 Lucas CG, Sloan EA, Gupta R, Wu J, Pratt D, Vasudevan HN, Ravindranathan A, Barreto J, Williams EA, Shai A, Whipple NS, Bruggers CS, Maher O, Nabors B, Rodriguez M, Samuel D, Brown M, Carmichael J, Lu…
• Serial H3K27M cell-free tumor DNA (cf-tDNA) tracking predicts ONC201 treatment response and progression in diffuse midline glioma.
  Neuro-oncology 2022 Cantor E, Wierzbicki K, Tarapore RS, Ravi K, Thomas C, Cartaxo R, Nand Yadav V, Ravindran R, Bruzek AK, Wadden J, John V, May Babila C, Cummings JR, Rahman Kawakibi A, Ji S, Ramos J, Paul A, Walling D…
• An Integrated Analysis of Clinical, Genomic, and Imaging Features Reveals Predictors of Neurocognitive Outcomes in a Longitudinal Cohort of Pediatric Cancer Survivors, Enriched with CNS Tumors (Rad ART Pro).
  Frontiers in oncology 2022 Kline C, Stoller S, Byer L, Samuel D, Lupo JM, Morrison MA, Rauschecker AM, Nedelec P, Faig W, Dubal DB, Fullerton HJ, Mueller S
• Mass cytometry detects H3.3K27M-specific vaccine responses in diffuse midline glioma.
  The Journal of clinical investigation 2022 Mueller S, Taitt JM, Villanueva-Meyer JE, Bonner ER, Nejo T, Lulla RR, Goldman S, Banerjee A, Chi SN, Whipple NS, Crawford JR, Gauvain K, Nazemi KJ, Watchmaker PB, Almeida ND, Okada K, Salazar AM, …
• Wee1 kinase inhibitor adavosertib with radiation in newly diagnosed diffuse intrinsic pontine glioma: A Children's Oncology Group phase I consortium study.
  Neuro-oncology advances 2022 Mueller S, Cooney T, Yang X, Pal S, Ermoian R, Gajjar A, Liu X, Prem K, Minard CG, Reid JM, Nelson M, Haas-Kogan D, Fox E, Weigel BJ
• Pediatric pineoblastoma: A pooled outcome study of North American and Australian therapeutic data.
  Neuro-oncology advances 2022 Hansford JR, Huang J, Endersby R, Dodgshun AJ, Li BK, Hwang E, Leary S, Gajjar A, Von Hoff K, Wells O, Wray A, Kotecha RS, Raleigh DR, Stoller S, Mueller S, Schild SE, Bandopadhayay P, Fouladi M, …
• Review: Neurological Complications From Therapies for Pediatric Brain Tumors.
  Frontiers in oncology 2022 Nguyen T, Mueller S, Malbari F
• Intracranial mesenchymal tumors with FET-CREB fusion are composed of at least two epigenetic subgroups distinct from meningioma and extracranial sarcomas.
  Brain pathology (Zurich, Switzerland) 2021 Sloan EA, Gupta R, Koelsche C, Chiang J, Villanueva-Meyer JE, Alexandrescu S, Eschbacher JM, Wang W, Mafra M, Ud Din N, Carr-Boyd E, Watson M, Punsoni M, Oviedo A, Gilani A, Kleinschmidt-DeMasters BK,…
• Preclinical and clinical evaluation of German-sourced ONC201 for the treatment of H3K27M-mutant diffuse intrinsic pontine glioma.
  Neuro-oncology advances 2021 Duchatel RJ, Mannan A, Woldu AS, Hawtrey T, Hindley PA, Douglas AM, Jackson ER, Findlay IJ, Germon ZP, Staudt D, Kearney PS, Smith ND, Hindley KE, Cain JE, André N, La Madrid AM, Nixon B, De Iuliis GN…
• Diffuse hemispheric glioma, H3 G34-mutant: Genomic landscape of a new tumor entity and prospects for targeted therapy.
  Neuro-oncology 2021 Lucas CG, Mueller S, Reddy A, Taylor JW, Oberheim Bush NA, Clarke JL, Chang SM, Gupta N, Berger MS, Perry A, Phillips JJ, Solomon DA
• Repurposing Vandetanib plus Everolimus for the Treatment of ACVR1-Mutant Diffuse Intrinsic Pontine Glioma.
  Cancer discovery 2021 Carvalho DM, Richardson PJ, Olaciregui N, Stankunaite R, Lavarino C, Molinari V, Corley EA, Smith DP, Ruddle R, Donovan A, Pal A, Raynaud FI, Temelso S, Mackay A, Overington JP, Phelan A, Sheppard D, …
• Author Correction: Topographic correlates of driver mutations and endogenous gene expression in pediatric diffuse midline gliomas and hemispheric high-grade gliomas.
  Scientific reports 2021 Kazarian E, Marks A, Cui J, Darbinyan A, Tong E, Mueller S, Cha S, Aboian MS
• Topographic correlates of driver mutations and endogenous gene expression in pediatric diffuse midline gliomas and hemispheric high-grade gliomas.
  Scientific reports 2021 Kazarian E, Marks A, Cui J, Darbinyan A, Tong E, Mueller S, Cha S, Aboian MS
• Radiation in Combination With Targeted Agents and Immunotherapies for Pediatric Central Nervous System Tumors - Progress, Opportunities, and Challenges.
  Frontiers in oncology 2021 Qiu B, Kline C, Mueller S
• Multi-institutional analysis of treatment modalities in basal ganglia and thalamic germinoma.
  Pediatric blood & cancer 2021 Graham RT, Abu-Arja MH, Stanek JR, Cappellano A, Coleman C, Chi S, Cooney T, Dhall G, Ellen JG, Finlay JL, Fisher MJ, Friedman GK, Gajjar A, Gauvain K, Hoffman LM, Hukin J, Lucas JT, Mueller S, …
• Relationship between 7T MR-angiography features of vascular injury and cognitive decline in young brain tumor patients treated with radiation therapy.
  Journal of neuro-oncology 2021 Avadiappan S, Morrison MA, Jakary A, Felton E, Stoller S, Hess CP, Molinaro AM, Braunstein SE, Mueller S, Lupo JM
• Mechanisms of imipridones in targeting mitochondrial metabolism in cancer cells.
  Neuro-oncology 2021 Bonner ER, Waszak SM, Grotzer MA, Mueller S, Nazarian J
• Optimal therapeutic targeting by HDAC inhibition in biopsy-derived treatment-naïve diffuse midline glioma models.
  Neuro-oncology 2021 Vitanza NA, Biery MC, Myers C, Ferguson E, Zheng Y, Girard EJ, Przystal JM, Park G, Noll A, Pakiam F, Winter CA, Morris SM, Sarthy J, Cole BL, Leary SES, Crane C, Lieberman NAP, Mueller S, Nazarian J,…
• Standardization of the liquid biopsy for pediatric diffuse midline glioma using ddPCR.
  Scientific reports 2021 Li D, Bonner ER, Wierzbicki K, Panditharatna E, Huang T, Lulla R, Mueller S, Koschmann C, Nazarian J, Saratsis AM
• Mass cytometry detects H3.3K27M-specific vaccine responses in diffuse midline glioma.
  The Journal of clinical investigation 2020 Mueller S, Taitt JM, Villanueva-Meyer JE, Bonner ER, Nejo T, Lulla RR, Goldman S, Banerjee A, Chi SN, Whipple NS, Crawford JR, Gauvain K, Nazemi KJ, Watchmaker PB, Almeida ND, Okada K, Salazar AM, …
• Opportunities for the treatment of NF1-associated low-grade gliomas: how to decide on the best treatment options for patients?
  Neuro-oncology 2020 Guerreiro Stücklin AS, Mueller S
• Everolimus improves the efficacy of dasatinib in PDGFRα-driven glioma.
  The Journal of clinical investigation 2020 Miklja Z, Yadav VN, Cartaxo RT, Siada R, Thomas CC, Cummings JR, Mullan B, Stallard S, Paul A, Bruzek AK, Wierzbicki K, Yang T, Garcia T, Wolfe I, Leonard M, Robertson PL, Garton HJ, Wahl DR, Parmar H…
• Rate of radiation-induced microbleed formation on 7T MRI relates to cognitive impairment in young patients treated with radiation therapy for a brain tumor.
  Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2020 Morrison MA, Mueller S, Felton E, Jakary A, Stoller S, Avadiappan S, Yuan J, Molinaro AM, Braunstein S, Banerjee A, Hess CP, Lupo JM
• Comprehensive analysis of diverse low-grade neuroepithelial tumors with FGFR1 alterations reveals a distinct molecular signature of rosette-forming glioneuronal tumor.
  Acta neuropathologica communications 2020 Lucas CG, Gupta R, Doo P, Lee JC, Cadwell CR, Ramani B, Hofmann JW, Sloan EA, Kleinschmidt-DeMasters BK, Lee HS, Wood MD, Grafe M, Born D, Vogel H, Salamat S, Puccetti D, Scharnhorst D, Samuel D, …
• Diffuse midline glioma: review of epigenetics.
  Journal of neuro-oncology 2020 Cooney TM, Lubanszky E, Prasad R, Hawkins C, Mueller S
• Response to Letter by Walker et al.
  Neuro-oncology practice 2020 Yeo KK, Mueller S
• Response to Karajannis et al.
  Neuro-oncology practice 2020 Cooney TM, Mueller S
• Harmonization of postmortem donations for pediatric brain tumors and molecular characterization of diffuse midline gliomas.
  Scientific reports 2020 Kambhampati M, Panditharatna E, Yadavilli S, Saoud K, Lee S, Eze A, Almira-Suarez MI, Hancock L, Bonner ER, Gittens J, Stampar M, Gaonkar K, Resnick AC, Kline C, Ho CY, Waanders AJ, Georgescu MM, …
• Response assessment in paediatric high-grade glioma: recommendations from the Response Assessment in Pediatric Neuro-Oncology (RAPNO) working group.
  The Lancet. Oncology 2020 Erker C, Tamrazi B, Poussaint TY, Mueller S, Mata-Mbemba D, Franceschi E, Brandes AA, Rao A, Haworth KB, Wen PY, Goldman S, Vezina G, MacDonald TJ, Dunkel IJ, Morgan PS, Jaspan T, Prados MD, Warren KE
• Population Pharmacokinetics of Vemurafenib in Children With Recurrent/Refractory BRAF Gene V600E-Mutant Astrocytomas.
  Journal of clinical pharmacology 2020 Wang H, Long-Boyle J, Winger BA, Nicolaides T, Mueller S, Prados M, Ivaturi V
• Phase I study of vemurafenib in children with recurrent or progressive BRAFV600E mutant brain tumors: Pacific Pediatric Neuro-Oncology Consortium study (PNOC-002).
  Oncotarget 2020 Nicolaides T, Nazemi KJ, Crawford J, Kilburn L, Minturn J, Gajjar A, Gauvain K, Leary S, Dhall G, Aboian M, Robinson G, Long-Boyle J, Wang H, Molinaro AM, Mueller S, Prados M
• Neurocognitive Outcomes in Children with Brain Tumors.
  Seminars in neurology 2020 Kline CN, Mueller S
• Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors.
  Nature medicine 2020 Theruvath J, Sotillo E, Mount CW, Graef CM, Delaidelli A, Heitzeneder S, Labanieh L, Dhingra S, Leruste A, Majzner RG, Xu P, Mueller S, Yecies DW, Finetti MA, Williamson D, Johann PD, Kool M, Pfister …
• Pediatric hemispheric high-grade glioma: targeting the future.
  Cancer metastasis reviews 2020 Coleman C, Stoller S, Grotzer M, Stucklin AG, Nazarian J, Mueller S
• Introduction. Pediatric brain tumor.
  Neurosurgical focus 2020 Cheshier S, Taylor MD, Ayrault O, Mueller S
• Stroke impact on mortality and psychologic morbidity within the Childhood Cancer Survivor Study.
  Cancer 2019 Mueller S, Kline CN, Buerki RA, Chen Y, Yasui Y, Howell R, Oeffinger KC, Leisenring WM, Robison LL, Armstrong GT, Fullerton HJ, Krull KR
• Comparative Tumor RNA Sequencing Analysis for Difficult-to-Treat Pediatric and Young Adult Patients With Cancer.
  JAMA network open 2019 Vaske OM, Bjork I, Salama SR, Beale H, Tayi Shah A, Sanders L, Pfeil J, Lam DL, Learned K, Durbin A, Kephart ET, Currie R, Newton Y, Swatloski T, McColl D, Vivian J, Zhu J, Lee AG, Leung SG, …
• Recurrent non-canonical histone H3 mutations in spinal cord diffuse gliomas.
  Acta neuropathologica 2019 Sloan EA, Cooney T, Oberheim Bush NA, Buerki R, Taylor J, Clarke JL, Torkildson J, Kline C, Reddy A, Mueller S, Banerjee A, Butowski N, Chang S, Mummaneni PV, Chou D, Tan L, Theodosopoulos P, …
• A systematic review and meta-analysis of outcomes in pediatric, recurrent ependymoma.
  Journal of neuro-oncology 2019 Byer L, Kline CN, Coleman C, Allen IE, Whitaker E, Mueller S
• Brainstem Injury in Pediatric Patients Receiving Posterior Fossa Photon Radiation.
  International journal of radiation oncology, biology, physics 2019 Devine CA, Liu KX, Ioakeim-Ioannidou M, Susko M, Poussaint TY, Huisman TAGM, Aboian M, Brown D, Zaslowe-Dude C, Rao AD, Orlina LT, Rawal B, Mueller S, Marcus KJ, Terezakis SA, Braunstein SE, Haas-…
• Pediatric and adult H3 K27M-mutant diffuse midline glioma treated with the selective DRD2 antagonist ONC201.
  Journal of neuro-oncology 2019 Chi AS, Tarapore RS, Hall MD, Shonka N, Gardner S, Umemura Y, Sumrall A, Khatib Z, Mueller S, Kline C, Zaky W, Khatua S, Weathers SP, Odia Y, Niazi TN, Daghistani D, Cherrick I, Korones D, Karajannis …
• Neuro-Oncology Practice Clinical Debate: targeted therapy vs conventional chemotherapy in pediatric low-grade glioma.
  Neuro-oncology practice 2019 Cooney T, Yeo KK, Kline C, Prados M, Haas-Kogan D, Chi S, Mueller S
• Molecular profiling and targeted therapy in pediatric gliomas: review and consensus recommendations.
  Neuro-oncology 2019 Miklja Z, Pasternak A, Stallard S, Nicolaides T, Kline-Nunnally C, Cole B, Beroukhim R, Bandopadhayay P, Chi S, Ramkissoon SH, Mullan B, Bruzek AK, Gauthier A, Garcia T, Atchison C, Marini B, Fouladi …
• Oncolytic Measles Virotherapy and Opposition to Measles Vaccination.
  Mayo Clinic proceedings 2019 Russell SJ, Babovic-Vuksanovic D, Bexon A, Cattaneo R, Dingli D, Dispenzieri A, Deyle DR, Federspiel MJ, Fielding A, Galanis E, Lacy MQ, Leibovich BC, Liu MC, Muñoz-Alía M, Miest TC, Molina JR, …
• Detection and Monitoring of Tumor Associated Circulating DNA in Patient Biofluids.
  Journal of visualized experiments : JoVE 2019 Bonner ER, Saoud K, Lee S, Panditharatna E, Kambhampati M, Mueller S, Nazarian J
• A pilot precision medicine trial for children with diffuse intrinsic pontine glioma-PNOC003: A report from the Pacific Pediatric Neuro-Oncology Consortium.
  International journal of cancer 2019 Mueller S, Jain P, Liang WS, Kilburn L, Kline C, Gupta N, Panditharatna E, Magge SN, Zhang B, Zhu Y, Crawford JR, Banerjee A, Nazemi K, Packer RJ, Petritsch CK, Truffaux N, Roos A, Nasser S, Phillips …
• The genetic landscape of anaplastic pleomorphic xanthoastrocytoma.
  Brain pathology (Zurich, Switzerland) 2018 Phillips JJ, Gong H, Chen K, Joseph NM, van Ziffle J, Bastian BC, Grenert JP, Kline CN, Mueller S, Banerjee A, Nicolaides T, Gupta N, Berger MS, Lee HS, Pekmezci M, Tihan T, Bollen AW, Perry A, Shieh …
• Clinically Relevant and Minimally Invasive Tumor Surveillance of Pediatric Diffuse Midline Gliomas Using Patient-Derived Liquid Biopsy.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2018 Panditharatna E, Kilburn LB, Aboian MS, Kambhampati M, Gordish-Dressman H, Magge SN, Gupta N, Myseros JS, Hwang EI, Kline C, Crawford JR, Warren KE, Cha S, Liang WS, Berens ME, Packer RJ, Resnick AC, …
• Prospective feasibility and safety assessment of surgical biopsy for patients with newly diagnosed diffuse intrinsic pontine glioma.
  Neuro-oncology 2018 Gupta N, Goumnerova LC, Manley P, Chi SN, Neuberg D, Puligandla M, Fangusaro J, Goldman S, Tomita T, Alden T, DiPatri A, Rubin JB, Gauvain K, Limbrick D, Leonard J, Geyer JR, Leary S, Browd S, Wang Z,…
• Reirradiation and PD-1 inhibition with nivolumab for the treatment of recurrent diffuse intrinsic pontine glioma: a single-institution experience.
  Journal of neuro-oncology 2018 Kline C, Liu SJ, Duriseti S, Banerjee A, Nicolaides T, Raber S, Gupta N, Haas-Kogan D, Braunstein S, Mueller S
• The genetic landscape of gliomas arising after therapeutic radiation.
  Acta neuropathologica 2018 López GY, Van Ziffle J, Onodera C, Grenert JP, Yeh I, Bastian BC, Clarke J, Oberheim Bush NA, Taylor J, Chang S, Butowski N, Banerjee A, Mueller S, Kline C, Torkildson J, Samuel D, Siongco A, Raffel C…
• Abnormal Morphology of Select Cortical and Subcortical Regions in Neurofibromatosis Type 1.
  Radiology 2018 Barkovich MJ, Tan CH, Nillo RM, Li Y, Xu D, Glastonbury CM, Glenn OA, Dillon WP, Hess CP, Mueller S, Kline C, Dale AM, Jernigan TL, Sugrue LP, Barkovich AJ, Desikan RS
• Social adjustment in adolescent survivors of pediatric central nervous system tumors: A report from the Childhood Cancer Survivor Study.
  Cancer 2018 Schulte F, Brinkman TM, Li C, Fay-McClymont T, Srivastava DK, Ness KK, Howell RM, Mueller S, Wells E, Strother D, Lafay-Cousin L, Leisenring W, Robison LL, Armstrong GT, Krull KR
• Clinical Applications of Quantitative 3-Dimensional MRI Analysis for Pediatric Embryonal Brain Tumors.
  International journal of radiation oncology, biology, physics 2018 Hara JH, Wu A, Villanueva-Meyer JE, Valdes G, Daggubati V, Mueller S, Solberg TD, Braunstein SE, Morin O, Raleigh DR
• The genetic landscape of ganglioglioma.
  Acta neuropathologica communications 2018 Pekmezci M, Villanueva-Meyer JE, Goode B, Van Ziffle J, Onodera C, Grenert JP, Bastian BC, Chamyan G, Maher OM, Khatib Z, Kleinschmidt-DeMasters BK, Samuel D, Mueller S, Banerjee A, Clarke JL, Cooney …
• Dual HDAC and PI3K Inhibition Abrogates NFκB- and FOXM1-Mediated DNA Damage Response to Radiosensitize Pediatric High-Grade Gliomas.
  Cancer research 2018 Pal S, Kozono D, Yang X, Fendler W, Fitts W, Ni J, Alberta JA, Zhao J, Liu KX, Bian J, Truffaux N, Weiss WA, Resnick AC, Bandopadhayay P, Ligon KL, DuBois SG, Mueller S, Chowdhury D, Haas-Kogan DA
• Large Vessel Arteriopathy After Cranial Radiation Therapy in Pediatric Brain Tumor Survivors.
  Journal of child neurology 2018 Nordstrom M, Felton E, Sear K, Tamrazi B, Torkildson J, Gauvain K, Haas-Kogan DA, Chen J, Buono BD, Banerjee A, Samuel D, Saloner D, Tian B, Roddy E, Hess C, Fullerton H, Mueller S
• Early detection of recurrent medulloblastoma: the critical role of diffusion-weighted imaging.
  Neuro-oncology practice 2018 Aboian MS, Kline CN, Li Y, Solomon DA, Felton E, Banerjee A, Braunstein SE, Mueller S, Dillon WP, Cha S
• Deep sequencing of WNT-activated medulloblastomas reveals secondary SHH pathway activation.
  Acta neuropathologica 2018 Iorgulescu JB, Van Ziffle J, Stevers M, Grenert JP, Bastian BC, Chavez L, Stichel D, Buchhalter I, Samuel D, Nicolaides T, Banerjee A, Mueller S, Gupta N, Tihan T, Bollen AW, Northcott PA, Kool M, …
• Pediatric low-grade gliomas: next biologically driven steps.
  Neuro-oncology 2018 Jones DTW, Kieran MW, Bouffet E, Alexandrescu S, Bandopadhayay P, Bornhorst M, Ellison D, Fangusaro J, Fisher MJ, Foreman N, Fouladi M, Hargrave D, Hawkins C, Jabado N, Massimino M, Mueller S, …
• Novel and shared neoantigen derived from histone 3 variant H3.3K27M mutation for glioma T cell therapy.
  The Journal of experimental medicine 2017 Chheda ZS, Kohanbash G, Okada K, Jahan N, Sidney J, Pecoraro M, Yang X, Carrera DA, Downey KM, Shrivastav S, Liu S, Lin Y, Lagisetti C, Chuntova P, Watchmaker PB, Mueller S, Pollack IF, Rajalingam R, …
• Survival outcomes in pediatric recurrent high-grade glioma: results of a 20-year systematic review and meta-analysis.
  Journal of neuro-oncology 2017 Kline C, Felton E, Allen IE, Tahir P, Mueller S
• New therapeutic approaches for brainstem tumors: a comparison of delivery routes using nanoliposomal irinotecan in an animal model.
  Journal of neuro-oncology 2017 Louis N, Liu S, He X, Drummond DC, Noble CO, Goldman S, Mueller S, Bankiewicz K, Gupta N, Hashizume R
• Overcoming resistance to single-agent therapy for oncogenic BRAF gene fusions via combinatorial targeting of MAPK and PI3K/mTOR signaling pathways.
  Oncotarget 2017 Jain P, Silva A, Han HJ, Lang SS, Zhu Y, Boucher K, Smith TE, Vakil A, Diviney P, Choudhari N, Raman P, Busch CM, Delaney T, Yang X, Olow AK, Mueller S, Haas-Kogan D, Fox E, Storm PB, Resnick AC, …
• Case-based review: pediatric medulloblastoma.
  Neuro-oncology practice 2017 Kline CN, Packer RJ, Hwang EI, Raleigh DR, Braunstein S, Raffel C, Bandopadhayay P, Solomon DA, Aboian M, Cha S, Mueller S
• Therapeutic and Prognostic Implications of BRAF V600E in Pediatric Low-Grade Gliomas.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2017 Lassaletta A, Zapotocky M, Mistry M, Ramaswamy V, Honnorat M, Krishnatry R, Guerreiro Stucklin A, Zhukova N, Arnoldo A, Ryall S, Ling C, McKeown T, Loukides J, Cruz O, de Torres C, Ho CY, Packer RJ, …
• Pediatric low-grade gliomas: implications of the biologic era.
  Neuro-oncology 2017 Packer RJ, Pfister S, Bouffet E, Avery R, Bandopadhayay P, Bornhorst M, Bowers DC, Ellison D, Fangusaro J, Foreman N, Fouladi M, Gajjar A, Haas-Kogan D, Hawkins C, Ho CY, Hwang E, Jabado N, Kilburn LB…
• Targeted next-generation sequencing of pediatric neuro-oncology patients improves diagnosis, identifies pathogenic germline mutations, and directs targeted therapy.
  Neuro-oncology 2017 Kline CN, Joseph NM, Grenert JP, van Ziffle J, Talevich E, Onodera C, Aboian M, Cha S, Raleigh DR, Braunstein S, Torkildson J, Samuel D, Bloomer M, Campomanes AGA, Banerjee A, Butowski N, Raffel C, …
• Pediatric high-grade glioma: current molecular landscape and therapeutic approaches.
  Journal of neuro-oncology 2017 Braunstein S, Raleigh D, Bindra R, Mueller S, Haas-Kogan D
• Pediatric high-grade glioma: biologically and clinically in need of new thinking.
  Neuro-oncology 2017 Jones C, Karajannis MA, Jones DTW, Kieran MW, Monje M, Baker SJ, Becher OJ, Cho YJ, Gupta N, Hawkins C, Hargrave D, Haas-Kogan DA, Jabado N, Li XN, Mueller S, Nicolaides T, Packer RJ, Persson AI, …
• Response to "Cognitive function, cerebral microbleeds, radiotherapy, and bevacizumab in survivors of paediatric brain tumors".
  Neuro-oncology 2017 Roddy E, Mueller S
• Survival after chemotherapy and stem cell transplant followed by delayed craniospinal irradiation is comparable to upfront craniospinal irradiation in pediatric embryonal brain tumor patients.
  Journal of neuro-oncology 2016 Raleigh DR, Tomlin B, Buono BD, Roddy E, Sear K, Byer L, Felton E, Banerjee A, Torkildson J, Samuel D, Horn B, Braunstein SE, Haas-Kogan DA, Mueller S
• Clinical trials in pediatric neuro-oncology: what is missing and how we can improve.
  CNS oncology 2016 Byer L, Kline C, Mueller S
• Presence of cerebral microbleeds is associated with worse executive function in pediatric brain tumor survivors.
  Neuro-oncology 2016 Roddy E, Sear K, Felton E, Tamrazi B, Gauvain K, Torkildson J, Buono BD, Samuel D, Haas-Kogan DA, Chen J, Goldsby RE, Banerjee A, Lupo JM, Molinaro AM, Fullerton HJ, Mueller S
• Evaluation of Pre-Hematopoietic Cell Transplantation (HCT) Brain MRI and Neurologic Complications of Pediatric Patients Undergoing HCT for Hematologic Malignancies.
  Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses 2016 Bailey-Olson M, Cowan M, Dvorak C, Mueller S, Owens A, Wahlstrom J, Horn B
• Inhibition of DNA damage repair by the CDK4/6 inhibitor palbociclib delays irradiated intracranial atypical teratoid rhabdoid tumor and glioblastoma xenograft regrowth.
  Neuro-oncology 2016 Hashizume R, Zhang A, Mueller S, Prados MD, Lulla RR, Goldman S, Saratsis AM, Mazar AP, Stegh AH, Cheng SY, Horbinski C, Haas-Kogan DA, Sarkaria JN, Waldman T, James CD
• BRAF Status in Personalizing Treatment Approaches for Pediatric Gliomas.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2016 Olow A, Mueller S, Yang X, Hashizume R, Meyerowitz J, Weiss W, Resnick AC, Waanders AJ, Stalpers LJ, Berger MS, Gupta N, James CD, Petritsch CK, Haas-Kogan DA
• IDH1 mutation can be present in diffuse astrocytomas and giant cell glioblastomas of young children under 10 years of age.
  Acta neuropathologica 2016 Ferris SP, Goode B, Joseph NM, Kline CN, Samuel D, Gupta N, Bollen A, Perry A, Mueller S, Solomon DA
• Inactivating MUTYH germline mutations in pediatric patients with high-grade midline gliomas.
  Neuro-oncology 2016 Kline CN, Joseph NM, Grenert JP, van Ziffle J, Yeh I, Bastian BC, Mueller S, Solomon DA
• Erratum to: Survival advantage combining a BRAF inhibitor and radiation in BRAF V600E-mutant glioma.
  Journal of neuro-oncology 2016 Dasgupta T, Olow AK, Yang X, Hashizume R, Nicolaides TP, Tom M, Aoki Y, Berger MS, Weiss WA, Stalpers LJ, Prados M, James CD, Mueller S, Haas-Kogan DA
• MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism.
  Nature genetics 2016 Bandopadhayay P, Ramkissoon LA, Jain P, Bergthold G, Wala J, Zeid R, Schumacher SE, Urbanski L, O'Rourke R, Gibson WJ, Pelton K, Ramkissoon SH, Han HJ, Zhu Y, Choudhari N, Silva A, Boucher K, Henn RE,…
• Clinical outcome and prognostic factors for central neurocytoma: twenty year institutional experience.
  Journal of neuro-oncology 2016 Imber BS, Braunstein SE, Wu FY, Nabavizadeh N, Boehling N, Weinberg VK, Tihan T, Barnes M, Mueller S, Butowski NA, Clarke JL, Chang SM, McDermott MM, Prados MD, Berger MS, Haas-Kogan DA
• Survival advantage combining a BRAF inhibitor and radiation in BRAF V600E-mutant glioma.
  Journal of neuro-oncology 2015 Dasgupta T, Olow AK, Yang X, Hashizume R, Nicolaides TP, Tom M, Aoki Y, Berger MS, Weiss WA, Stalpers LJ, Prados M, James CD, Mueller S, Haas-Kogan DA
• Recurrent stroke in childhood cancer survivors.
  Neurology 2015 Fullerton HJ, Stratton K, Mueller S, Leisenring WW, Armstrong GT, Weathers RE, Stovall M, Sklar CA, Goldsby RE, Robison LL, Krull KR
• EAG2 potassium channel with evolutionarily conserved function as a brain tumor target.
  Nature neuroscience 2015 Huang X, He Y, Dubuc AM, Hashizume R, Zhang W, Reimand J, Yang H, Wang TA, Stehbens SJ, Younger S, Barshow S, Zhu S, Cooper MK, Peacock J, Ramaswamy V, Garzia L, Wu X, Remke M, Forester CM, Kim CC, …
• WEE1 Kinase As a Target for Cancer Therapy.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2015 Mueller S, Haas-Kogan DA
• Late Effects of Treatment of Pediatric Central Nervous System Tumors.
  Journal of child neurology 2015 Roddy E, Mueller S
• Posttranscriptional deregulation of signaling pathways in meningioma subtypes by differential expression of miRNAs.
  Neuro-oncology 2015 Ludwig N, Kim YJ, Mueller SC, Backes C, Werner TV, Galata V, Sartorius E, Bohle RM, Keller A, Meese E
• Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma.
  Nature medicine 2014 Hashizume R, Andor N, Ihara Y, Lerner R, Gan H, Chen X, Fang D, Huang X, Tom MW, Ngo V, Solomon D, Mueller S, Paris PL, Zhang Z, Petritsch C, Gupta N, Waldman TA, James CD
• Pure germinomas of the central nervous system: treatment strategies and outcomes.
  Journal of neuro-oncology 2014 Schoenfeld A, Haas-Kogan DA, Molinaro A, Banerjee A, Nicolaides T, Tihan T, Bollen AW, Gupta N, Mueller S
• Rates and characteristics of radiographically detected intracerebral cavernous malformations after cranial radiation therapy in pediatric cancer patients.
  Journal of child neurology 2014 Gastelum E, Sear K, Hills N, Roddy E, Randazzo D, Chettout N, Hess C, Cotter J, Haas-Kogan DA, Fullerton H, Mueller S
• Germ-line and somatic DICER1 mutations in pineoblastoma.
  Acta neuropathologica 2014 de Kock L, Sabbaghian N, Druker H, Weber E, Hamel N, Miller S, Choong CS, Gottardo NG, Kees UR, Rednam SP, van Hest LP, Jongmans MC, Jhangiani S, Lupski JR, Zacharin M, Bouron-Dal Soglio D, Huang A, …
• Targeting Wee1 for the treatment of pediatric high-grade gliomas.
  Neuro-oncology 2013 Mueller S, Hashizume R, Yang X, Kolkowitz I, Olow AK, Phillips J, Smirnov I, Tom MW, Prados MD, James CD, Berger MS, Gupta N, Haas-Kogan DA
• The alternative lengthening of telomere phenotype is significantly associated with loss of ATRX expression in high-grade pediatric and adult astrocytomas: a multi-institutional study of 214 astrocytomas.
  Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2013 Abedalthagafi M, Phillips JJ, Kim GE, Mueller S, Haas-Kogen DA, Marshall RE, Croul SE, Santi MR, Cheng J, Zhou S, Sullivan LM, Martinez-Lage M, Judkins AR, Perry A
• Radiation, atherosclerotic risk factors, and stroke risk in survivors of pediatric cancer: a report from the Childhood Cancer Survivor Study.
  International journal of radiation oncology, biology, physics 2013 Mueller S, Fullerton HJ, Stratton K, Leisenring W, Weathers RE, Stovall M, Armstrong GT, Goldsby RE, Packer RJ, Sklar CA, Bowers DC, Robison LL, Krull KR
• Feasibility, safety, and indications for surgical biopsy of intrinsic brainstem tumors in children.
  Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2013 Cage TA, Samagh SP, Mueller S, Nicolaides T, Haas-Kogan D, Prados M, Banerjee A, Auguste KI, Gupta N
• Risk of first and recurrent stroke in childhood cancer survivors treated with cranial and cervical radiation therapy.
  International journal of radiation oncology, biology, physics 2013 Mueller S, Sear K, Hills NK, Chettout N, Afghani S, Gastelum E, Haas-Kogan D, Fullerton HJ
• The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression.
  Genes & development 2013 Chan KM, Fang D, Gan H, Hashizume R, Yu C, Schroeder M, Gupta N, Mueller S, James CD, Jenkins R, Sarkaria J, Zhang Z
• PDGFRA amplification is common in pediatric and adult high-grade astrocytomas and identifies a poor prognostic group in IDH1 mutant glioblastoma.
  Brain pathology (Zurich, Switzerland) 2013 Phillips JJ, Aranda D, Ellison DW, Judkins AR, Croul SE, Brat DJ, Ligon KL, Horbinski C, Venneti S, Zadeh G, Santi M, Zhou S, Appin CL, Sioletic S, Sullivan LM, Martinez-Lage M, Robinson AE, Yong WH, …
• Poly (ADP-Ribose) polymerase inhibitor MK-4827 together with radiation as a novel therapy for metastatic neuroblastoma.
  Anticancer research 2013 Mueller S, Bhargava S, Molinaro AM, Yang X, Kolkowitz I, Olow A, Wehmeijer N, Orbach S, Chen J, Matthay KK, Haas-Kogan DA
• Multidisciplinary care of patients with brain tumors.
  Surgical oncology clinics of North America 2013 Huang T, Mueller S, Rutkowski MJ, Han SJ, Bloch O, Barani IJ, Parsa AT, Chang SM
• Characterization of a diffuse intrinsic pontine glioma cell line: implications for future investigations and treatment.
  Journal of neuro-oncology 2012 Hashizume R, Smirnov I, Liu S, Phillips JJ, Hyer J, McKnight TR, Wendland M, Prados M, Banerjee A, Nicolaides T, Mueller S, James CD, Gupta N
• PTEN promoter methylation and activation of the PI3K/Akt/mTOR pathway in pediatric gliomas and influence on clinical outcome.
  Neuro-oncology 2012 Mueller S, Phillips J, Onar-Thomas A, Romero E, Zheng S, Wiencke JK, McBride SM, Cowdrey C, Prados MD, Weiss WA, Berger MS, Gupta N, Haas-Kogan DA
• High-grade gliomas in children.
  Neurosurgery clinics of North America 2012 Cage TA, Mueller S, Haas-Kogan D, Gupta N
• The superiority of conservative resection and adjuvant radiation for craniopharyngiomas.
  Journal of neuro-oncology 2012 Schoenfeld A, Pekmezci M, Barnes MJ, Tihan T, Gupta N, Lamborn KR, Banerjee A, Mueller S, Chang S, Berger MS, Haas-Kogan D
• Cooperation of the HDAC inhibitor vorinostat and radiation in metastatic neuroblastoma: efficacy and underlying mechanisms.
  Cancer letters 2011 Mueller S, Yang X, Sottero TL, Gragg A, Prasad G, Polley MY, Weiss WA, Matthay KK, Davidoff AM, DuBois SG, Haas-Kogan DA
• Vorinostat increases expression of functional norepinephrine transporter in neuroblastoma in vitro and in vivo model systems.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2011 More SS, Itsara M, Yang X, Geier EG, Tadano MK, Seo Y, Vanbrocklin HF, Weiss WA, Mueller S, Haas-Kogan DA, Dubois SG, Matthay KK, Giacomini KM
• Inhibition of PI3K/mTOR pathways in glioblastoma and implications for combination therapy with temozolomide.
  Neuro-oncology 2011 Prasad G, Sottero T, Yang X, Mueller S, James CD, Weiss WA, Polley MY, Ozawa T, Berger MS, Aftab DT, Prados MD, Haas-Kogan DA
• Effect of imaging and catheter characteristics on clinical outcome for patients in the PRECISE study.
  Journal of neuro-oncology 2010 Mueller S, Polley MY, Lee B, Kunwar S, Pedain C, Wembacher-Schröder E, Mittermeyer S, Westphal M, Sampson JH, Vogelbaum MA, Croteau D, Chang SM
• Neuroblastoma: biology and staging.
  Current oncology reports 2009 Mueller S, Matthay KK
• T-cell lymphoproliferative disorder following mycophenolate treatment for myasthenia gravis.
  Muscle & nerve 2009 Dubal DB, Mueller S, Ruben BS, Engstrom JW, Josephson SA
• A case of paraneoplastic myelopathy associated with the neuromyelitis optica antibody.
  Nature clinical practice. Neurology 2008 Mueller S, Dubal DB, Josephson SA
• Functional comparison of long and short splice forms of RPTPbeta: implications for glioblastoma treatment.
  Neuro-oncology 2005 Lorente G, Nelson A, Mueller S, Kuo J, Urfer R, Nikolich K, Foehr ED