Ryan Chang, MD, PhD
Clinical Fellow
Medicine
School of Medicine

Publications (13)

Top publication keywords:
Interferon Type IOncolytic VirotherapyMelanomaHypoxia-Inducible Factor 1Cell- and Tissue-Based TherapyAdaptive ImmunityCancer VaccinesImmunotherapyNanotechnologyNanoparticlesHypoxia-Inducible Factor 1, alpha SubunitT-LymphocytesReceptors, Antigen, T-Cell, gamma-deltaPeritoneal CavityAntigen-Presenting Cells

• γδ T cells as critical anti-tumor immune effectors.
  Nature cancer 2024 Arias-Badia M, Chang R, Fong L
• Vaccinating against cancer: getting to prime time.
  Journal for immunotherapy of cancer 2023 Chang R, Gulley JL, Fong L
• Multi-Immune Agonist Nanoparticle Therapy Stimulates Type I Interferons to Activate Antigen-Presenting Cells and Induce Antigen-Specific Antitumor Immunity.
  Molecular pharmaceutics 2021 Levy ES, Chang R, Zamecnik CR, Dhariwala MO, Fong L, Desai TA
• DNA scaffolds enable efficient and tunable functionalization of biomaterials for immune cell modulation.
  Nature nanotechnology 2020 Huang X, Williams JZ, Chang R, Li Z, Burnett CE, Hernandez-Lopez R, Setiady I, Gai E, Patterson DM, Yu W, Roybal KT, Lim WA, Desai TA
• DNA-scaffolded biomaterials enable modular and tunable presentation of proteins to control immune cell therapies.
  The Journal of Immunology 2020 Xiao Huang, Jasper Z. Williams, Ryan Chang, Zhongbo Li, Eric Gai, David M. Patterson, Yu Wei, Wendell A. Lim, Tejal Desai

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• Optimization of a Polycaprolactone (PCL) Scaffold for Islet and Cellular Transplantation.
  Transplantation Journal 2018 Steven Wisel, Gaetano Faleo, Nicole Conkling, Ryan Chang, Peter Stock, Tejal Desai, Qizhi Tang
• Nanoporous Immunoprotective Device for Stem-Cell-Derived β-Cell Replacement Therapy.
  ACS nano 2017 Chang R, Faleo G, Russ HA, Parent AV, Elledge SK, Bernards DA, Allen JL, Villanueva K, Hebrok M, Tang Q, Desai TA
• Polycaprolactone Thin-Film Micro- and Nanoporous Cell-Encapsulation Devices.
  ACS nano 2015 Nyitray CE, Chang R, Faleo G, Lance KD, Bernards DA, Tang Q, Desai TA
• Imaging assessment of a portable hemodialysis device: detection of possible failure modes and monitoring of functional performance.
  Medical instrumentation (Luton, England) 2014 Olorunsola OG, Kim SH, Chang R, Kuo YC, Hetts SW, Heller A, Kant R, Saeed M, Fissell WH, Roy S, Wilson MW
• Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression.
  Proceedings of the National Academy of Sciences of the United States of America 2012 Luo W, Chang R, Zhong J, Pandey A, Semenza GL
• Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1.
  Cell 2011 Luo W, Hu H, Chang R, Zhong J, Knabel M, O'Meally R, Cole RN, Pandey A, Semenza GL
• Impaired angiogenesis and mobilization of circulating angiogenic cells in HIF-1alpha heterozygous-null mice after burn wounding.
  Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2010 Zhang X, Liu L, Wei X, Tan YS, Tong L, Chang R, Ghanamah MS, Reinblatt M, Marti GP, Harmon JW, Semenza GL
• Hsp70 and CHIP selectively mediate ubiquitination and degradation of hypoxia-inducible factor (HIF)-1alpha but Not HIF-2alpha.
  The Journal of biological chemistry 2009 Luo W, Zhong J, Chang R, Hu H, Pandey A, Semenza GL