Rupal Shah, MD
Associate Professor
Medicine
School of Medicine

She is the Medical Director for Adult Patient Experience at UCSF Health and is passionate about improving the care, communication, and experience of patients who seek care at UCSF Health. Dr. Shah received her undergraduate degree from University of Michigan, and a Masters in Clinical Epidemiology from University of Pennsylvania. She completed medical school at Wayne State University School of Medicine and did her internal medicine residency at Columbia University and advanced training in pulmonary and critical care medicine at University of Pennsylvania. She is board certified in Internal Medicine, Pulmonary Medicine, and Critical Care Medicine.

• Design and implementation of a digital health home spirometry intervention for remote monitoring of lung transplant function.
  The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2023 Odisho AY, Liu AW, Maiorano AR, Bigazzi MOA, Medina E, Leard LE, Shah R, Venado A, Perez A, Golden J, Kleinhenz ME, Kolaitis NA, Maheshwari J, Trinh BN, Kukreja J, Greenland J, Calabrese D, Neinstein …
• Impact of a Multidisciplinary Post-COVID-19 Clinic on Hospital Admissions and ED Visits.
  Chest 2023 Levan S, Mourad M, Block B, Shah R, Santhosh L
• NKG2D receptor activation drives primary graft dysfunction severity and poor lung transplantation outcomes.
  JCI insight 2022 Calabrese DR, Tsao T, Magnen M, Valet C, Gao Y, Mallavia B, Tian JJ, Aminian EA, Wang KM, Shemesh A, Punzalan EB, Sarma A, Calfee CS, Christenson SA, Langelier CR, Hays SR, Golden JA, Leard LE, …
• Nirmatrelvir/ritonavir Use With Tacrolimus in Lung Transplant Recipients: A Single-center Case Series.
  Transplantation 2022 Dewey KW, Yen B, Lazo J, Seijo L, Jariwala R, Shah RJ, Quan D, Carpenter B, Paul Singer J, Breen K, Hays S, Florez R
• Critical Care of the Lung Transplant Patient.
  Clinics in chest medicine 2022 Perez AA, Shah RJ
• Depressive symptoms in lung transplant recipients: trajectory and association with mortality and allograft dysfunction.
  Thorax 2022 Kolaitis NA, Gao Y, Soong A, Greenland JR, Hays SR, Golden JA, Venado A, Leard LE, Shah RJ, Kleinhenz ME, Katz PP, Kukreja J, Blanc PD, Smith PJ, Singer JP
• Proteomic biomarkers of progressive fibrosing interstitial lung disease: a multicentre cohort analysis.
  The Lancet. Respiratory medicine 2022 Bowman WS, Newton CA, Linderholm AL, Neely ML, Pugashetti JV, Kaul B, Vo V, Echt GA, Leon W, Shah RJ, Huang Y, Garcia CK, Wolters PJ, Oldham JM
• Response.
  Chest 2022 Santhosh L, Block B, Kim SY, Raju S, Shah RJ, Thakur N, Brigham EP, Parker AM
• Lung Allograft Epithelium DNA Methylation Age Is Associated With Graft Chronologic Age and Primary Graft Dysfunction.
  Frontiers in immunology 2021 Dugger DT, Calabrese DR, Gao Y, Deiter F, Tsao T, Maheshwari J, Hays SR, Leard L, Kleinhenz ME, Shah R, Golden J, Kukreja J, Gordon ED, Singer JP, Greenland JR
• Construct and Predictive Validity of Sarcopenia in Lung Transplant Candidates.
  Annals of the American Thoracic Society 2021 Maheshwari JA, Kolaitis NA, Anderson MR, Benvenuto L, Gao Y, Katz PP, Greenland J, Wolters PJ, Covinsky K, Hays SR, Kukreja J, Calabrese DR, Venado A, Shah RJ, Leard LE, Trinh B, Huang CY, Glidden D, …
• ISHLT consensus document on lung transplantation in patients with connective tissue disease: Part I: Epidemiology, assessment of extrapulmonary conditions, candidate evaluation, selection criteria, and pathology statements.
  The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2021 Crespo MM, Lease ED, Sole A, Sandorfi N, Snyder LD, Berry GJ, Pavec JL, Venado AE, Cifrian JM, Goldberg H, Dilling DF, Gries C, Nair A, Willie K, Meyer KC, Shah RJ, Tokman S, Holm A, Patterson CM, …
• A Novel Ambulatory Curriculum for Pulmonary and Critical Care Fellowship Training.
  ATS scholar 2021 Kassutto SM, Santhosh L, Dine CJ, Kreider M, Lapin J, Shah RJ
• Better Together: A Mixed-Methods Study of Palliative Care Co-Management for Patients with Interstitial Lung Disease.
  Journal of palliative medicine 2021 Bischoff KE, Choi S, Su A, Cohen E, O'Riordan DL, Oettel E, Blachman M, Meister S, Zapata C, Lindenfeld P, Calton B, Witt L, Pantilat SZ, Shah RJ
• Rapid Design and Implementation of Post-COVID-19 Clinics.
  Chest 2021 Santhosh L, Block B, Kim SY, Raju S, Shah RJ, Thakur N, Brigham EP, Parker AM
• The association of post-operative delirium with patient-reported outcomes and mortality after lung transplantation.
  Clinical transplantation 2021 DeBolt CL, Gao Y, Sutter N, Soong A, Leard L, Jeffrey G, Kleinhenz ME, Calabrese D, Greenland J, Venado A, Hays SR, Shah R, Kukreja J, Trinh B, Kolaitis NA, Douglas V, Diamond JM, Smith P, Singer J
• Strategies for forming effective women's groups.
  The clinical teacher 2020 Santhosh L, Harleman E, Venado A, Farrand E, E Gilbreth M, Keenan BP, Thompson VV, Shah RJ
• Chronic lung allograft dysfunction small airways reveal a lymphocytic inflammation gene signature.
  American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2020 Dugger DT, Fung M, Hays SR, Singer JP, Kleinhenz ME, Leard LE, Golden JA, Shah RJ, Lee JS, Deiter F, Greenland NY, Jones KD, Langelier CR, Greenland JR
• Primary graft dysfunction attenuates improvements in health-related quality of life after lung transplantation, but not disability or depression.
  American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2020 Kolaitis NA, Gao Y, Soong A, Greenland JR, Hays SR, Golden J, Leard LE, Shah RJ, Kleinhenz ME, Katz PP, Venado A, Kukreja J, Blanc PD, Singer JP
• Cystic Fibrosis Lung Transplant Recipients Have Suppressed Airway Interferon Responses during Pseudomonas Infection.
  Cell reports. Medicine 2020 Dugger DT, Fung M, Zlock L, Caldera S, Sharp L, Hays SR, Singer JP, Leard LE, Golden JA, Shah RJ, Kukreja J, Gordon E, Finkbeiner W, Kleinhenz ME, Langelier C, Greenland JR
• Psychological contributors to the frail phenotype: The association between resilience and frailty in patients with cirrhosis.
  American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2020 Wong RJ, Mohamad Y, Srisengfa YT, Kent DS, Seetharaman S, Shah RJ, Lai JC
• Frailty after lung transplantation is associated with impaired health-related quality of life and mortality.
  Thorax 2020 Venado A, Kolaitis NA, Huang CY, Gao Y, Glidden DV, Soong A, Sutter N, Katz PP, Greenland JR, Calabrese DR, Hays SR, Golden JA, Shah RJ, Leard LE, Kukreja J, Deuse T, Wolters PJ, Covinsky K, Blanc PD,…
• Improvements in frailty contribute to substantial improvements in quality of life after lung transplantation in patients with cystic fibrosis.
  Pediatric pulmonology 2020 Perez AA, Hays SR, Soong A, Gao Y, Greenland JR, Leard LE, Shah RJ, Golden J, Kukreja J, Venado A, Kleinhenz ME, Singer JP
• Mitochondrial DNA Stimulates TLR9-Dependent Neutrophil Extracellular Trap Formation in Primary Graft Dysfunction.
  American journal of respiratory cell and molecular biology 2020 Mallavia B, Liu F, Lefrançais E, Cleary SJ, Kwaan N, Tian JJ, Magnen M, Sayah DM, Soong A, Chen J, Saggar R, Shino MY, Ross DJ, Derhovanessian A, Lynch JP, Ardehali A, Weigt SS, Belperio JA, Hays SR, …
• Giant cell interstitial pneumonia secondary to cobalt exposure from e-cigarette use.
  The European respiratory journal 2019 Fels Elliott DR, Shah R, Hess CA, Elicker B, Henry TS, Rule AM, Chen R, Golozar M, Jones KD
• Tacrolimus trough monitoring guided by mass spectrometry without accounting for assay differences is associated with acute kidney injury in lung transplant recipients.
  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 2019 Kolaitis NA, Calabrese DR, Ahearn P, Venado A, Florez R, Lei HL, Isaak K, Henricksen E, Martinez E, Chong T, Shah RJ, Leard LE, Kleinhenz ME, Golden J, De Marco T, Greenland JR, Kukreja J, Hays SR, …
• The Role of Spirometry and Dyspnea Index in the Management of Subglottic Stenosis.
  The Laryngoscope 2019 Tie K, Buckmire RA, Shah RN
• Collagen type-V is a danger signal associated with primary graft dysfunction in lung transplantation.
  Transplant immunology 2019 Zaffiri L, Shah RJ, Stearman RS, Rothhaar K, Emtiazjoo AM, Yoshimoto M, Fisher AJ, Mickler EA, Gartenhaus MD, Cohort LTOG, Diamond JM, Geraci MW, Christie JD, Wilkes DS
• Management and clinical outcomes after lung transplantation in patients with pre-transplant Mycobacterium abscessus infection: A single center experience.
  Transplant infectious disease : an official journal of the Transplantation Society 2019 Perez AA, Singer JP, Schwartz BS, Chin-Hong P, Shah RJ, Kleinhenz ME, Gao Y, Venado A, Leard LE, Golden JA, Kukreja J, Greenland JR, Hays SR
• Frailty trajectories in adult lung transplantation: A cohort study.
  The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2019 Venado A, McCulloch C, Greenland JR, Katz P, Soong A, Shrestha P, Hays S, Golden J, Shah R, Leard LE, Kleinhenz ME, Kukreja J, Zablotska L, Allen IE, Covinsky K, Blanc P, Singer JP
• Frailty phenotypes and mortality after lung transplantation: A prospective cohort study.
  American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2018 Singer JP, Diamond JM, Anderson MR, Katz PP, Covinsky K, Oyster M, Blue T, Soong A, Kalman L, Shrestha P, Arcasoy SM, Greenland JR, Shah L, Kukreja J, Blumenthal NP, Easthausen I, Golden JA, McBurnie …
• Burden, resilience and coping in caregivers of patients with interstitial lung disease.
  Heart & lung : the journal of critical care 2018 Shah RJ, Collard HR, Morisset J
• Primary Graft Dysfunction (PGD) Following Lung Transplantation.
  Seminars in respiratory and critical care medicine 2018 Shah RJ, Diamond JM
• Improvement in patient-reported outcomes after lung transplantation is not impacted by the use of extracorporeal membrane oxygenation as a bridge to transplantation.
  The Journal of thoracic and cardiovascular surgery 2018 Kolaitis NA, Soong A, Shrestha P, Zhuo H, Neuhaus J, Katz PP, Greenland JR, Golden J, Leard LE, Shah RJ, Hays SR, Kukreja J, Kleinhenz ME, Blanc PD, Singer JP
• Clinical Risk Factors and Prognostic Model for Primary Graft Dysfunction after Lung Transplantation in Patients with Pulmonary Hypertension.
  Annals of the American Thoracic Society 2017 Porteous MK, Lee JC, Lederer DJ, Palmer SM, Cantu E, Shah RJ, Bellamy SL, Lama VN, Bhorade SM, Crespo MM, McDyer JF, Wille KM, Localio AR, Orens JB, Shah PD, Weinacker AB, Arcasoy S, Wilkes DS, Ware …
• Update in Chronic Lung Allograft Dysfunction.
  Clinics in chest medicine 2017 Shah RJ, Diamond JM
• Exposure to Ambient Particulate Matter Is Associated With Accelerated Functional Decline in Idiopathic Pulmonary Fibrosis.
  Chest 2017 Winterbottom CJ, Shah RJ, Patterson KC, Kreider ME, Panettieri RA, Rivera-Lebron B, Miller WT, Litzky LA, Penning TM, Heinlen K, Jackson T, Localio AR, Christie JD
• Refining Low Physical Activity Measurement Improves Frailty Assessment in Advanced Lung Disease and Survivors of Critical Illness.
  Annals of the American Thoracic Society 2017 Baldwin MR, Singer JP, Huang D, Sell J, Gonzalez WC, Pollack LR, Maurer MS, D'Ovidio FF, Bacchetta M, Sonett JR, Arcasoy SM, Shah L, Robbins H, Hays SR, Kukreja J, Greenland JR, Shah RJ, Leard L, …
• The Hospitalized Patient with Interstitial Lung Disease: A Hospitalist Primer.
  Journal of hospital medicine 2017 Farrand E, Shah R, Collard H
• Lung Transplantation in Patients With Systemic Sclerosis.
  Current rheumatology reports 2017 Shah RJ, Boin F
• Effect of Lung Transplantation on Health-Related Quality of Life in the Era of the Lung Allocation Score: A U.S. Prospective Cohort Study.
  American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2017 Singer JP, Katz PP, Soong A, Shrestha P, Huang D, Ho J, Mindo M, Greenland JR, Hays SR, Golden J, Kukreja J, Kleinhenz ME, Shah RJ, Blanc PD
• Interstitial Lung Disease in the Elderly.
  Chest 2016 Patterson KC, Shah RJ, Porteous MK, Christie JD, D'Errico CA, Chadwick M, Triano MJ, Deshpande C, Rossman MD, Litzky LA, Kreider M, Miller WT
• Diastolic Dysfunction Increases the Risk of Primary Graft Dysfunction after Lung Transplant.
  American journal of respiratory and critical care medicine 2016 Porteous MK, Ky B, Kirkpatrick JN, Shinohara R, Diamond JM, Shah RJ, Lee JC, Christie JD, Kawut SM
• Changing the Ambulatory Training Paradigm. Design and Implementation of an Outpatient Pulmonology Fellowship Curriculum.
  Annals of the American Thoracic Society 2016 Kassutto SM, Dine CJ, Kreider M, Shah RJ
• The relationship between plasma lipid peroxidation products and primary graft dysfunction after lung transplantation is modified by donor smoking and reperfusion hyperoxia.
  The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2016 Diamond JM, Porteous MK, Roberts LJ, Wickersham N, Rushefski M, Kawut SM, Shah RJ, Cantu E, Lederer DJ, Chatterjee S, Lama VN, Bhorade S, Crespo M, McDyer J, Wille K, Orens J, Weinacker A, Arcasoy S, …
• Survey of Lung Transplant Community's Views on Primary Graft Dysfunction.
  American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2016 Diamond JM, Shah RJ, Cantu E, Porteous MK, Christie JD
• Patient Satisfaction: Why and How Patients Grade You and Your Pulmonary Practice.
  Chest 2015 Kassutto SM, Shah RJ
• Objective Estimates Improve Risk Stratification for Primary Graft Dysfunction after Lung Transplantation.
  American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2015 Shah RJ, Diamond JM, Cantu E, Flesch J, Lee JC, Lederer DJ, Lama VN, Orens J, Weinacker A, Wilkes DS, Roe D, Bhorade S, Wille KM, Ware LB, Palmer SM, Crespo M, Demissie E, Sonnet J, Shah A, Kawut SM, …
• Body composition and mortality after adult lung transplantation in the United States.
  American journal of respiratory and critical care medicine 2014 Singer JP, Peterson ER, Snyder ME, Katz PP, Golden JA, D'Ovidio F, Bacchetta M, Sonett JR, Kukreja J, Shah L, Robbins H, Van Horn K, Shah RJ, Diamond JM, Wickersham N, Sun L, Hays S, Arcasoy SM, …
• Oxidant stress regulatory genetic variation in recipients and donors contributes to risk of primary graft dysfunction after lung transplantation.
  The Journal of thoracic and cardiovascular surgery 2014 Cantu E, Shah RJ, Lin W, Daye ZJ, Diamond JM, Suzuki Y, Ellis JH, Borders CF, Andah GA, Beduhn B, Meyer NJ, Ruschefski M, Aplenc R, Feng R, Christie JD, Lung Transplant Outcomes Group Investigators
• Plasma complement levels are associated with primary graft dysfunction and mortality after lung transplantation.
  American journal of respiratory and critical care medicine 2014 Shah RJ, Emtiazjoo AM, Diamond JM, Smith PA, Roe DW, Wille KM, Orens JB, Ware LB, Weinacker A, Lama VN, Bhorade SM, Palmer SM, Crespo M, Lederer DJ, Cantu E, Eckert GJ, Christie JD, Wilkes DS
• Cognitive function, mental health, and health-related quality of life after lung transplantation.
  Annals of the American Thoracic Society 2014 Cohen DG, Christie JD, Anderson BJ, Diamond JM, Judy RP, Shah RJ, Cantu E, Bellamy SL, Blumenthal NP, Demissie E, Hopkins RO, Mikkelsen ME
• Genetic variation in the prostaglandin E2 pathway is associated with primary graft dysfunction.
  American journal of respiratory and critical care medicine 2014 Diamond JM, Akimova T, Kazi A, Shah RJ, Cantu E, Feng R, Levine MH, Kawut SM, Meyer NJ, Lee JC, Hancock WW, Aplenc R, Ware LB, Palmer SM, Bhorade S, Lama VN, Weinacker A, Orens J, Wille K, Crespo M, …
• Preoperative plasma club (clara) cell secretory protein levels are associated with primary graft dysfunction after lung transplantation.
  American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2014 Shah RJ, Wickersham N, Lederer DJ, Palmer SM, Cantu E, Diamond JM, Kawut SM, Lama VN, Bhorade S, Crespo M, Demissie E, Sonett J, Wille K, Orens J, Weinacker A, Shah P, Arcasoy S, Wilkes DS, Christie …
• Response.
  Chest 2014 Shah RJ, Christie JD
• Latent class analysis identifies distinct phenotypes of primary graft dysfunction after lung transplantation.
  Chest 2013 Shah RJ, Diamond JM, Cantu E, Lee JC, Lederer DJ, Lama VN, Orens J, Weinacker A, Wilkes DS, Bhorade S, Wille KM, Ware LB, Palmer SM, Crespo M, Localio AR, Demissie E, Kawut SM, Bellamy SL, Christie JD
• Lung transplantation for obstructive lung diseases.
  Seminars in respiratory and critical care medicine 2013 Shah RJ, Kotloff RM
• Gene set enrichment analysis identifies key innate immune pathways in primary graft dysfunction after lung transplantation.
  American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2013 Cantu E, Lederer DJ, Meyer K, Milewski K, Suzuki Y, Shah RJ, Diamond JM, Meyer NJ, Tobias JW, Baldwin DA, Van Deerlin VM, Olthoff KM, Shaked A, Christie JD, CTOT Investigators
• Beware of gloved fingers.
  Annals of the American Thoracic Society 2013 Shah RJ, Kotloff RM
• Early plasma soluble receptor for advanced glycation end-product levels are associated with bronchiolitis obliterans syndrome.
  American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2013 Shah RJ, Bellamy SL, Lee JC, Cantu E, Diamond JM, Mangalmurti N, Kawut SM, Ware LB, Christie JD
• Clinical risk factors for primary graft dysfunction after lung transplantation.
  American journal of respiratory and critical care medicine 2013 Diamond JM, Lee JC, Kawut SM, Shah RJ, Localio AR, Bellamy SL, Lederer DJ, Cantu E, Kohl BA, Lama VN, Bhorade SM, Crespo M, Demissie E, Sonett J, Wille K, Orens J, Shah AS, Weinacker A, Arcasoy S, …
• Elevated plasma angiopoietin-2 levels and primary graft dysfunction after lung transplantation.
  PloS one 2012 Diamond JM, Porteous MK, Cantu E, Meyer NJ, Shah RJ, Lederer DJ, Kawut SM, Lee J, Bellamy SL, Palmer SM, Lama VN, Bhorade SM, Crespo M, Demissie E, Wille K, Orens J, Shah PD, Weinacker A, Weill D, …
• Plasma monocyte chemotactic protein-1 levels at 24 hours are a biomarker of primary graft dysfunction after lung transplantation.
  Translational research : the journal of laboratory and clinical medicine 2012 Shah RJ, Diamond JM, Lederer DJ, Arcasoy SM, Cantu EM, Demissie EJ, Kawut SM, Kohl B, Lee JC, Sonett J, Christie JD, Ware LB
• Variation in PTX3 is associated with primary graft dysfunction after lung transplantation.
  American journal of respiratory and critical care medicine 2012 Diamond JM, Meyer NJ, Feng R, Rushefski M, Lederer DJ, Kawut SM, Lee JC, Cantu E, Shah RJ, Lama VN, Bhorade S, Crespo M, Demissie E, Sonett J, Wille K, Orens J, Weinacker A, Weill D, Arcasoy S, Shah …
• A panel of lung injury biomarkers enhances the definition of primary graft dysfunction (PGD) after lung transplantation.
  The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2012 Shah RJ, Bellamy SL, Localio AR, Wickersham N, Diamond JM, Weinacker A, Lama VN, Bhorade S, Belperio JA, Crespo M, Demissie E, Kawut SM, Wille KM, Lederer DJ, Lee JC, Palmer SM, Orens J, Reynolds J, …