Rosmely Hernandez, PhD
Scientist
Business Service Ctr
Chancellor/EVC/FAS

Publications (7)

Top publication keywords:
Virulence FactorsMutagenesisRegulatory Elements, TranscriptionalT-Lymphocytes, RegulatoryType III Secretion SystemsPlagueGene EditingInterleukin-2 Receptor alpha SubunitRegulatory Sequences, Nucleic AcidSTAT5 Transcription FactorYersinia pestisForkhead Transcription FactorsAdenocarcinomaHost-Pathogen InteractionsAlleles

• FOXP3 expression depends on cell-type-specific cis-regulatory elements and transcription factor circuitry.
  Immunity 2025 Umhoefer JM, Arce MM, Kasinathan S, Whalen S, Dajani R, Subramanya S, Goudy L, Belk JA, Zhou R, Pham MTN, Zhang W, Hernandez R, Tran C, Kirthivasan N, Freimer JW, Mowery CT, Nguyen V, Ota M, Gowen BG,…
• Integrated epigenetic and genetic programming of primary human T cells.
  Nature biotechnology 2025 Goudy L, Ha A, Borah AA, Umhoefer JM, Chow L, Tran C, Winters A, Talbot A, Hernandez R, Li Z, Subramanya S, Arab A, Kale N, Lee JHJ, Muldoon JJ, Liu C, Schmidt R, Santangelo P, Carnevale J, Eyquem J, …
• Cis-Regulatory Element and Transcription Factor Circuitry Required for Cell-Type Specific Expression of FOXP3.
  bioRxiv : the preprint server for biology 2025 Umhoefer JM, Arce MM, Whalen S, Dajani R, Goudy L, Kasinathan S, Belk JA, Zhang W, Zhou R, Subramanya S, Hernandez R, Tran C, Kirthivasan N, Freimer JW, Mowery CT, Nguyen V, Ota M, Gowen BG, Simeonov …
• Base-editing mutagenesis maps alleles to tune human T cell functions.
  Nature 2023 Schmidt R, Ward CC, Dajani R, Armour-Garb Z, Ota M, Allain V, Hernandez R, Layeghi M, Xing G, Goudy L, Dorovskyi D, Wang C, Chen YY, Ye CJ, Shy BR, Gilbert LA, Eyquem J, Pritchard JK, Dodgson SE, …
• POLQ inhibition elicits an immune response in homologous recombination-deficient pancreatic adenocarcinoma via cGAS/STING signaling.
  The Journal of clinical investigation 2023 Oh G, Wang A, Wang L, Li J, Werba G, Weissinger D, Zhao E, Dhara S, Hernandez RE, Ackermann A, Porcella S, Kalfakakou D, Dolgalev I, Kawaler E, Golan T, Welling TH, Sfeir A, Simeone DM
• Acute Lipopolysaccharide-Induced Inflammation Lowers IL-2R Signaling and the Proliferative Potential of Regulatory T Cells.
  ImmunoHorizons 2020 Hsiung S, Moro A, Ban Y, Chen X, Savio AS, Hernandez R, Malek TR
• Chromosomally-Encoded Yersinia pestis Type III Secretion Effector Proteins Promote Infection in Cells and in Mice.
  Frontiers in cellular and infection microbiology 2019 Schesser Bartra S, Lorica C, Qian L, Gong X, Bahnan W, Barreras H, Hernandez R, Li Z, Plano GV, Schesser K