Rosemary Akhurst, PhD
Professor
HDF Comprehensive Cancer Ctr
School of Medicine

As part of my ongoing work, I am an active participant in projects aimed at reducing cancer health disparities and furthering our understanding of cancer progression. This journey into discovery and understanding is ongoing and I am continually learning and expanding upon my research.

• Genetic polymorphism in Methylenetetrahydrofolate Reductase chloride transport protein 6 (MTHFR CLCN6) gene is associated with keratinocyte skin cancer in a cohort of renal transplant recipients.
  Skin health and disease 2022 Griffin L, Ho L, Akhurst RJ, Arron ST, Boggs JME, Conlon P, O'Kelly P, Toland AE, Epstein EH, Balmain A, Bastian BC, Moloney FJ, Murphy GM, Laing ME
• TGFβ: Signaling Blockade for Cancer Immunotherapy.
  Annual review of cancer biology 2021 Chen SY, Mamai O, Akhurst RJ
• Integrin αvβ8 on T cells suppresses anti-tumor immunity in multiple models and is a promising target for tumor immunotherapy.
  Cell reports 2021 Dodagatta-Marri E, Ma HY, Liang B, Li J, Meyer DS, Chen SY, Sun KH, Ren X, Zivak B, Rosenblum MD, Headley MB, Pinzas L, Reed NI, Del Cid JS, Hann BC, Yang S, Giddabasappa A, Noorbehesht K, Yang B, Dal…
• TGFβ biology in cancer progression and immunotherapy.
  Nature reviews. Clinical oncology 2020 Derynck R, Turley SJ, Akhurst RJ
• α-PD-1 therapy elevates Treg/Th balance and increases tumor cell pSmad3 that are both targeted by α-TGFβ antibody to promote durable rejection and immunity in squamous cell carcinomas.
  Journal for immunotherapy of cancer 2019 Dodagatta-Marri E, Meyer DS, Reeves MQ, Paniagua R, To MD, Binnewies M, Broz ML, Mori H, Wu D, Adoumie M, Del Rosario R, Li O, Buchmann T, Liang B, Malato J, Arce Vargus F, Sheppard D, Hann BC, Mirza …
• Chronic TGF-β exposure drives stabilized EMT, tumor stemness, and cancer drug resistance with vulnerability to bitopic mTOR inhibition.
  Science signaling 2019 Katsuno Y, Meyer DS, Zhang Z, Shokat KM, Akhurst RJ, Miyazono K, Derynck R
• Enhanced TGF-β Signaling Contributes to the Insulin-Induced Angiogenic Responses of Endothelial Cells.
  iScience 2019 Budi EH, Mamai O, Hoffman S, Akhurst RJ, Derynck R
• From prevention to cure, repurposing anti-viral vaccines for cancer immunotherapy.
  Biotarget 2018 Mamai O, Dodagatta-Marri E, Akhurst RJ
• Smad3-mediated recruitment of the methyltransferase SETDB1/ESET controls Snail1 expression and epithelial-mesenchymal transition.
  EMBO reports 2017 Du D, Katsuno Y, Meyer D, Budi EH, Chen SH, Koeppen H, Wang H, Akhurst RJ, Derynck R
• Targeting TGF-β Signaling for Therapeutic Gain.
  Cold Spring Harbor perspectives in biology 2017 Akhurst RJ
• ShcA Protects against Epithelial-Mesenchymal Transition through Compartmentalized Inhibition of TGF-β-Induced Smad Activation.
  PLoS biology 2015 Muthusamy BP, Budi EH, Katsuno Y, Lee MK, Smith SM, Mirza AM, Akhurst RJ, Derynck R
• Defining Primary Marrow Microenvironment-Induced Synthetic Lethality and Resistance for 2,684 Approved Drugs Across Molecularly Distinct Forms of Multiple Myeloma.
  Blood 2015 Megan Murnane, Eugen Dhimolea, Ruojing Li, Megan A. Bariteau, Diamond D. Wheeler, Rosemary J. Akhurst, Aaron C. Logan, Pamela Munster, Arun Wiita, Thomas G. Martin, Jeffrey L. Wolf, Jun O. Liu, …
• Matters of context guide future research in TGFβ superfamily signaling.
  Science signaling 2015 Akhurst RJ, Padgett RW
• Genetic variation in the functional ENG allele inherited from the non-affected parent associates with presence of pulmonary arteriovenous malformation in hereditary hemorrhagic telangiectasia 1 (HHT1) and may influence expression of PTPN14.
  Frontiers in genetics 2015 Letteboer TG, Benzinou M, Merrick CB, Quigley DA, Zhau K, Kim IJ, To MD, Jablons DM, van Amstel JK, Westermann CJ, Giraud S, Dupuis-Girod S, Lesca G, Berg JH, Balmain A, Akhurst RJ
• Excessive vascular sprouting underlies cerebral hemorrhage in mice lacking αVβ8-TGFβ signaling in the brain.
  Development (Cambridge, England) 2014 Arnold TD, Niaudet C, Pang MF, Siegenthaler J, Gaengel K, Jung B, Ferrero GM, Mukouyama YS, Fuxe J, Akhurst R, Betsholtz C, Sheppard D, Reichardt LF
• Genetic variants of Adam17 differentially regulate TGFβ signaling to modify vascular pathology in mice and humans.
  Proceedings of the National Academy of Sciences of the United States of America 2014 Kawasaki K, Freimuth J, Meyer DS, Lee MM, Tochimoto-Okamoto A, Benzinou M, Clermont FF, Wu G, Roy R, Letteboer TG, Ploos van Amstel JK, Giraud S, Dupuis-Girod S, Lesca G, Westermann CJ, Coffey RJ, …
• BMP-9 balances endothelial cell fate.
  Proceedings of the National Academy of Sciences of the United States of America 2013 Derynck R, Akhurst RJ
• Multiple self-healing squamous epithelioma (MSSE): rare variants in an adjacent region of chromosome 9q22.3 to known TGFBR1 mutations suggest a digenic or multilocus etiology.
  The Journal of investigative dermatology 2013 Kang HC, Quigley DA, Kim IJ, Wakabayashi Y, Ferguson-Smith MA, D'Alessandro M, Birgitte Lane E, Akhurst RJ, Goudie DR, Balmain A
• Erratum: Targeting the TGFß signalling pathway in disease.
  Nature Reviews Drug Discovery 2012 Rosemary J. Akhurst, Akiko Hata
• Epistatic interactions between Tgfb1 and genetic loci, Tgfbm2 and Tgfbm3, determine susceptibility to an asthmatic stimulus.
  Proceedings of the National Academy of Sciences of the United States of America 2012 Freimuth J, Clermont FF, Huang X, DeSapio A, Tokuyasu TA, Sheppard D, Akhurst RJ
• Targeting the TGFβ signalling pathway in disease.
  Nature reviews. Drug discovery 2012 Akhurst RJ, Hata A
• The paradoxical TGF-β vasculopathies.
  Nature genetics 2012 Akhurst RJ
• Complexities of TGF-β targeted cancer therapy.
  International journal of biological sciences 2012 Connolly EC, Freimuth J, Akhurst RJ
• TGF- -induced activation of mTOR complex 2 drives epithelial-mesenchymal transition and cell invasion.
  Development 2012 S. Lamouille, E. Connolly, J. W. Smyth, R. J. Akhurst, R. Derynck
• TGF-β-induced activation of mTOR complex 2 drives epithelial-mesenchymal transition and cell invasion.
  Journal of cell science 2012 Lamouille S, Connolly E, Smyth JW, Akhurst RJ, Derynck R
• Defective retinal vascular endothelial cell development as a consequence of impaired integrin αVβ8-mediated activation of transforming growth factor-β.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2012 Arnold TD, Ferrero GM, Qiu H, Phan IT, Akhurst RJ, Huang EJ, Reichardt LF
• Mouse and human strategies identify PTPN14 as a modifier of angiogenesis and hereditary haemorrhagic telangiectasia.
  Nature communications 2012 Benzinou M, Clermont FF, Letteboer TG, Kim JH, Espejel S, Harradine KA, Arbelaez J, Luu MT, Roy R, Quigley D, Higgins MN, Zaid M, Aouizerat BE, van Amstel JK, Giraud S, Dupuis-Girod S, Lesca G, …
• Erratum: Mouse and human strategies identify PTPN14 as a modifier of angiogenesis and hereditary haemorrhagic telangiectasia.
  Nature Communications 2012 Michael Benzinou, Frederic F. Clermont, Tom G W. Letteboer, Jai-hyun Kim, Silvia Espejel, Kelly A. Harradine, Juan Arbelaez, Minh Thu Luu, Ritu Roy, David Quigley, Mamie Nakayama Higgins, Musa Zaid, …
• The complexities of TGF-β action during mammary and squamous cell carcinogenesis.
  Current pharmaceutical biotechnology 2011 Connolly EC, Akhurst RJ
• TGFβ1 inhibition increases the radiosensitivity of breast cancer cells in vitro and promotes tumor control by radiation in vivo.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2011 Bouquet F, Pal A, Pilones KA, Demaria S, Hann B, Akhurst RJ, Babb JS, Lonning SM, DeWyngaert JK, Formenti SC, Barcellos-Hoff MH
• Outgrowth of drug-resistant carcinomas expressing markers of tumor aggression after long-term TβRI/II kinase inhibition with LY2109761.
  Cancer research 2011 Connolly EC, Saunier EF, Quigley D, Luu MT, De Sapio A, Hann B, Yingling JM, Akhurst RJ
• Taking thalidomide out of rehab.
  Nature medicine 2010 Akhurst RJ
• Elevated cutaneous Smad activation associates with enhanced skin tumor susceptibility in organ transplant recipients.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2009 Harradine KA, Ridd K, Saunier EF, Clermont FF, Perez-Losada J, Moore DH, Epstein EH, Bastian BC, Akhurst RJ
• Transforming growth factor-beta in breast cancer: too much, too late.
  Breast cancer research : BCR 2009 Barcellos-Hoff MH, Akhurst RJ
• The type I TGF-beta receptor is covalently modified and regulated by sumoylation.
  Nature cell biology 2008 Kang JS, Saunier EF, Akhurst RJ, Derynck R
• Reversal of EMT by Small-Molecule Inhibitors of TGF-ß Type I and II Receptors: Implications for Carcinoma Treatment.
  Transforming Growth Factor-ß in Cancer Therapy, Volume II 2008 Markus D. Lacher, W. Michael Korn, Rosemary J. Akhurst
• Differentiation plasticity regulated by TGF-beta family proteins in development and disease.
  Nature cell biology 2007 Derynck R, Akhurst RJ
• Characterization of Tgfbm2, a genetic modifier of Tgfb1-/- embryonic lethality.
  The FASEB Journal 2007 Frederic Clermont, Minh Thu Luu, Mamie Higgins, Rosemary J Akhurst
• TGF beta inhibition for cancer therapy.
  Current cancer drug targets 2006 Saunier EF, Akhurst RJ
• Large- and small-molecule inhibitors of transforming growth factor-beta signaling.
  Current opinion in investigational drugs (London, England : 2000) 2006 Akhurst RJ
• Genetic variants of Tgfb1 act as context-dependent modifiers of mouse skin tumor susceptibility.
  Proceedings of the National Academy of Sciences of the United States of America 2006 Mao JH, Saunier EF, de Koning JP, McKinnon MM, Higgins MN, Nicklas K, Yang HT, Balmain A, Akhurst RJ
• A sweet link between TGFbeta and vascular disease?
  Nature genetics 2006 Akhurst RJ
• Transforming growth factor-beta receptor inhibition enhances adenoviral infectability of carcinoma cells via up-regulation of Coxsackie and Adenovirus Receptor in conjunction with reversal of epithelial-mesenchymal transition.
  Cancer research 2006 Lacher MD, Tiirikainen MI, Saunier EF, Christian C, Anders M, Oft M, Balmain A, Akhurst RJ, Korn WM
• TGFbeta inhibition of yolk-sac-like differentiation of human embryonic stem-cell-derived embryoid bodies illustrates differences between early mouse and human development.
  Journal of cell science 2006 Poon E, Clermont F, Firpo MT, Akhurst RJ
• Mutations of TGFbeta signaling molecules in human disease.
  Annals of medicine 2006 Harradine KA, Akhurst RJ
• Epistatic interactions between modifier genes confer strain-specific redundancy for Tgfb1 in developmental angiogenesis.
  Genomics 2005 Tang Y, Lee KS, Yang H, Logan DW, Wang S, McKinnon ML, Holt LJ, Condie A, Luu MT, Akhurst RJ
• TGF beta signaling in health and disease.
  Nature genetics 2004 Akhurst RJ
• Cancer: dangerous liaisons.
  Nature 2004 Balmain A, Akhurst RJ
• Mouse strain-dependent heterogeneity of resting limbal vasculature.
  Investigative ophthalmology & visual science 2004 Chan CK, Pham LN, Chinn C, Spee C, Ryan SJ, Akhurst RJ, Hinton DR
• Genetic modifiers interact with maternal determinants in vascular development of Tgfb1(-/-) mice.
  Human molecular genetics 2003 Tang Y, McKinnon ML, Leong LM, Rusholme SA, Wang S, Akhurst RJ
• Transforming growth factor-beta1 mediates cellular response to DNA damage in situ.
  Cancer research 2002 Ewan KB, Henshall-Powell RL, Ravani SA, Pajares MJ, Arteaga C, Warters R, Akhurst RJ, Barcellos-Hoff MH
• Metastasis is driven by sequential elevation of H-ras and Smad2 levels.
  Nature cell biology 2002 Oft M, Akhurst RJ, Balmain A
• Latent transforming growth factor-beta activation in mammary gland: regulation by ovarian hormones affects ductal and alveolar proliferation.
  The American journal of pathology 2002 Ewan KB, Shyamala G, Ravani SA, Tang Y, Akhurst R, Wakefield L, Barcellos-Hoff MH
• TGF-beta antagonists: why suppress a tumor suppressor?
  The Journal of clinical investigation 2002 Akhurst RJ
• TGF-beta signaling in cancer--a double-edged sword.
  Trends in cell biology 2001 Akhurst RJ, Derynck R
• TGF-ß signaling in cancer — a double-edged sword.
  Trends in Cell Biology 2001 Rosemary J. Akhurst, Rik Derynck
• TGF-beta signaling in tumor suppression and cancer progression.
  Nature genetics 2001 Derynck R, Akhurst RJ, Balmain A
• Isolation, identification, and molecular characterization of strains of Photorhabdus luminescens from infected humans in Australia.
  Journal of clinical microbiology 1999 Peel MM, Alfredson DA, Gerrard JG, Davis JM, Robson JM, McDougall RJ, Scullie BL, Akhurst RJ
• Genetic events and the role of TGF beta in epithelial tumour progression.
  The Journal of pathology 1999 Akhurst RJ, Balmain A
• Epithelial carcinogenesis in the mouse: correlating the genetics and the biology.
  Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1998 Frame S, Crombie R, Liddell J, Stuart D, Linardopoulos S, Nagase H, Portella G, Brown K, Street A, Akhurst R, Balmain A
• Transforming growth factor beta is essential for spindle cell conversion of mouse skin carcinoma in vivo: implications for tumor invasion.
  Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1998 Portella G, Cumming SA, Liddell J, Cui W, Ireland H, Akhurst RJ, Balmain A
• Mapping of a major genetic modifier of embryonic lethality in TGF beta 1 knockout mice.
  Nature genetics 1997 Bonyadi M, Rusholme SA, Cousins FM, Su HC, Biron CA, Farrall M, Akhurst RJ
• TGFbeta1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice.
  Cell 1996 Cui W, Fowlis DJ, Bryson S, Duffie E, Ireland H, Balmain A, Akhurst RJ
• Altered epidermal cell growth control in vivo by inducible expression of transforming growth factor beta 1 in the skin of transgenic mice.
  Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1996 Fowlis DJ, Cui W, Johnson SA, Balmain A, Akhurst RJ
• The TGF beta type II receptor, Tgfbr2, maps to distal mouse chromosome 9.
  Genomics 1996 Bonyadi M, Cui W, Nagase H, Akhurst RJ
• The role of transforming growth factor ß during cardiovascular development.
  Molecular Physiology of Growth 1996 Marion C. Dickson, Julie S. Martin, Rosemary J. Akhurst
• Transforming growth factor ßS: Biochemistry and biological activities in vitro and in vivo.
  Growth Factors 1996 Wei Cui, Rosemary J. Akhurst
• Liposome-medicated gene transfer and expression via the skin.
  Human molecular genetics 1995 Alexander MY, Akhurst RJ
• Circulating human factor IX produced in keratin-promoter transgenic mice: a feasibility study for gene therapy of haemophilia B.
  Human molecular genetics 1995 Alexander MY, Bidichandani SI, Cousins FM, Robinson CJ, Duffie E, Akhurst RJ
• Defective haematopoiesis and vasculogenesis in transforming growth factor-beta 1 knock out mice.
  Development (Cambridge, England) 1995 Dickson MC, Martin JS, Cousins FM, Kulkarni AB, Karlsson S, Akhurst RJ
• Concerted action of TGF-beta 1 and its type II receptor in control of epidermal homeostasis in transgenic mice.
  Genes & development 1995 Cui W, Fowlis DJ, Cousins FM, Duffie E, Bryson S, Balmain A, Akhurst RJ
• Analysis of homozygous TGF beta 1 null mouse embryos demonstrates defects in yolk sac vasculogenesis and hematopoiesis.
  Annals of the New York Academy of Sciences 1995 Martin JS, Dickson MC, Cousins FM, Kulkarni AB, Karlsson S, Akhurst RJ
• Lack of transforming growth factor-beta 1 expression in benign skin tumors of p53null mice is prognostic for a high risk of malignant conversion.
  Cancer research 1994 Cui W, Kemp CJ, Duffie E, Balmain A, Akhurst RJ
• Localization of transforming growth factor-alpha RNA and protein in the skin of psoriatic patients receiving therapy.
  The British journal of dermatology 1994 Watts P, Stables GS, Akhurst RJ, Mackie RM
• Physical methods of gene delivery using keratinocytes as a target for somatic cell gene therapy.
  Gene therapy 1994 Alexander MY, Bidichandani S, Robinson C, Trainer AH, Akhurst RJ
• Localization of growth factor mRNA in tissue sections by in situ hybridization.
  Growth Factors 1993 Rosemary J Akhurst
• RNA and protein localisations of TGF beta 2 in the early mouse embryo suggest an involvement in cardiac development.
  Development (Cambridge, England) 1993 Dickson MC, Slager HG, Duffie E, Mummery CL, Akhurst RJ
• Positive and negative growth control in multistage skin carcinogenesis.
  Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 1993 Brown K, Kemp CJ, Burns PA, Stoler AB, Fowlis DJ, Akhurst RJ, Balmain A
• Rapid induction and clearance of TGF beta 1 is an early response to wounding in the mouse embryo.
  Developmental genetics 1993 Martin P, Dickson MC, Millan FA, Akhurst RJ
• Transforming growth factor ßs and cardiac development.
  Growth Factors and the Cardiovascular System 1993 Rosemary J. Akhurst, Marion Dickson, Fergus A. Millan
• The role of TGF-beta s in mammalian development and neoplasia.
  Molecular reproduction and development 1992 Akhurst RJ, Fitzpatrick DR, Fowlis DJ, Gatherer D, Millan FA, Slager H
• Palatal expression of TGF-ß isoforms in normal and retinoic acid-treated mouse embryos.
  Retinoids in Normal Development and Teratogenesis 1992 David R FitzPatrick, Barbara D Abbott, Rosemary J Akhurst
• Discordant transforming growth factor beta 1 RNA and protein localization during chemical carcinogenesis of the skin.
  Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1992 Fowlis DJ, Flanders KC, Duffie E, Balmain A, Akhurst RJ
• Enormous scope for further research peptide growth factors and their receptors vol. I (1990). Edited by M. B. Sporn and A. B. Roberts. Springer-Verlag: Berlin. 785pp. DM 398. ISBN 3 540 51184 9.
  BioEssays 1992 Rosemary Akhurst
• Loss of growth control by TGF-beta occurs at a late stage of mouse skin carcinogenesis and is independent of ras gene activation.
  Oncogene 1991 Haddow S, Fowlis DJ, Parkinson K, Akhurst RJ, Balmain A
• Embryonic gene expression patterns of TGF beta 1, beta 2 and beta 3 suggest different developmental functions in vivo.
  Development (Cambridge, England) 1991 Millan FA, Denhez F, Kondaiah P, Akhurst RJ
• Functional loss of tumour suppressor genes in multistage chemical carcinogenesis.
  Princess Takamatsu symposia 1991 Balmain A, Kemp CJ, Burns PA, Stoler AB, Fowlis DJ, Akhurst RJ
• Expression of TGF-beta isoforms during first trimester human embryogenesis.
  Development (Cambridge, England) 1990 Gatherer D, Ten Dijke P, Baird DT, Akhurst RJ
• Localization of elevated transforming growth factor-alpha in psoriatic epidermis.
  The Journal of investigative dermatology 1990 Turbitt ML, Akhurst RJ, White SI, MacKie RM
• Differential expression of TGF beta isoforms in murine palatogenesis.
  Development (Cambridge, England) 1990 Fitzpatrick DR, Denhez F, Kondaiah P, Akhurst RJ
• TGF beta in murine morphogenetic processes: the early embryo and cardiogenesis.
  Development (Cambridge, England) 1990 Akhurst RJ, Lehnert SA, Faissner A, Duffie E
• The role of TGF beta in mouse development.
  Annals of the New York Academy of Sciences 1990 Akhurst RJ, Lehnert SA, Gatherer D, Duffie E
• Transforming growth factor betas in mammalian embryogenesis.
  Progress in growth factor research 1990 Akhurst RJ, FitzPatrick DR, Gatherer D, Lehnert SA, Millan FA
• The role of transforming growth factor-ß in mouse development and carcinogenesis.
  Biochemical Society Transactions 1989 ROSEMARY J. AKHURST, SIGRID A. LEHNERT, FRANCES FEE, ALLAN BALMAIN
• Chemical induction of oncogene mutations and growth factor activity in mouse skin carcinogenesis.
  Environmental health perspectives 1989 Bailleul B, Brown K, Ramsden M, Akhurst RJ, Fee F, Balmain A
• Intracellular localisation and expression of mammalian CDC2 protein during myogenic differentiation.
  Differentiation; research in biological diversity 1989 Akhurst RJ, Flavin NB, Worden J, Lee MG
• Prospects for Gene Therapy Now and in the Future.
  Studies in Inherited Metabolic Disease 1989 R. J. Akhurst
• Prospects for gene therapy now and in the future.
  Journal of inherited metabolic disease 1989 Akhurst RJ
• The action of oncogenes and growth factors in tumour initiation and promotion.
  Carcinogenesis; a comprehensive survey 1989 Akhurst R, Bailleul B, Brown K, Ramsden M, Fee F, Balmain A
• Molecular analysis of chemical carcinogenesis in the skin.
  The British journal of cancer. Supplement 1988 Balmain A, Brown K, Akhurst RJ, Fee FM
• Chorionic gonadotrophin-beta mRNA, a trophoblast marker, is expressed in human 8-cell embryos derived from tripronucleate zygotes.
  Human reproduction (Oxford, England) 1988 Bonduelle ML, Dodd R, Liebaers I, Van Steirteghem A, Williamson R, Akhurst R
• Embryonic expression pattern of TGF beta type-1 RNA suggests both paracrine and autocrine mechanisms of action.
  Development (Cambridge, England) 1988 Lehnert SA, Akhurst RJ
• Isolation and Characterization of a Variant Myoblast Cell Line That is Temperature Sensitive for Differentiation.
  Molecular and Cellular Biology 1988 Rosemary J. Akhurst, Nora B. Flavin, Jenny Worden
• Isolation and characterization of a variant myoblast cell line that is temperature sensitive for differentiation.
  Molecular and cellular biology 1988 Akhurst RJ, Flavin NB, Worden J
• Isolation and characterization of a variant myoblast cell line that is temperature sensitive for differentiation.
  Molecular and Cellular Biology 1988 R J Akhurst, N B Flavin, J Worden
• Localized production of TGF-beta mRNA in tumour promoter-stimulated mouse epidermis.
  Nature 1988 Akhurst RJ, Fee F, Balmain A
• Sea urchin actin gene linkages determined by genetic segregation.
  Developmental biology 1987 Minor JE, Lee JJ, Akhurst RJ, Leahy PS, Britten RJ, Davidson EH
• Structure and organization of the CyIII actin gene subfamily of the sea urchin, Strongylocentrotus purpuratus.
  Journal of molecular biology 1987 Akhurst RJ, Calzone FJ, Lee JJ, Britten RJ, Davidson EH
• The use of gene probes in studying human reproduction and embryology.
  Human reproduction (Oxford, England) 1986 Akhurst RJ
• Sea urchin actin gene subtypes. Gene number, linkage and evolution.
  Journal of molecular biology 1984 Lee JJ, Shott RJ, Rose SJ, Thomas TL, Britten RJ, Davidson EH
• Dev. Biol
  Differential expression of the actin gene family of Strongylocentrotus purpuratus 1984 Akhurst RJ (Shott RJ) Lee JJ, Britten RJ, Davidson EH
• Regulation of the relative abundances of mRNAs in hepatoma and liver.
  Advances in experimental medicine and biology 1982 Birnie GD, Jacobs H, Shott R, Wilkes PR
• Post-transcriptional control of messenger abundance.
  Molecular biology reports 1981 Birnie GD, Balmain A, Jacobs H, Shott R, Wilkes PR, Paul J