Rosanna Wustrack, MD
Associate Professor
Orthopaedic Surgery
School of Medicine
rosanna.wustrack@ucsf.edu 415-885-3800
Dr. Rosanna Wustrack is the Chief of Orthopedic Oncology and an orthopedic surgeon who specializes in the surgical diagnosis and treatment of musculoskeletal tumors and fragility fractures. Her research focuses on immunotherapy for sarcomas, functional outcomes in cancer patients, osseointegration and optimizing treatment for metastatic disease.
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She also is interested in global health and osteoporosis in cancer survivors.
Dr. Wustrack received an undergraduate degree from Yale University before earning a medical degree from Washington University School of Medicine in St. Louis. She completed an internship and residency in orthopedic surgery at UCSF. Subsequently, she completed fellowship training in musculoskeletal oncology at Memorial Sloan Kettering Cancer Center in New York.
Awards
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- Muriel Steele Society Honor Roll, UCSF Muriel Steele Society, 2021-2022
- Compassionate Physician Award, UCSF Department of Orthopedic Surgery, 2020
- Exceptional Physician Award, UCSF Health, 2020
- Muriel Steele Society Honor Roll, UCSF Muriel Steele Society, 2020
- Mentored Research Award, Musculoskeletal Research Society, 2019-2020
- Identifying and enhancing the host immune response in adult soft tissue sarcoma, UCSF RAP Grant Program, 2018-2019
- Excellence in Teaching Award, UCSF Academy of Medical Educators, 2018
- James O. Johnston Resident Teaching Award, UCSF Department of Orthopedic Surgery, 2016
- Mauer Chief Resident of the Year, UCSF Department of Orthopedic Surgery, 2012
Education & Training
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- Diversity, Equity, and Inclusion Champion Training University of California 2018
- Certificate Advanced Training in Clinical Research University of California San Francisco 2014
- Fellowship Musculoskeletal Oncology Memorial Sloan Kettering Cancer Center 2013
- Residency Orthopedic Surgery University of California San Francisco Department of Orthopedic Surgery 2012
- MD Medicine Washington University in St. Louis Medical School 2006
- BA Biology Yale University 1999
Interests
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- Sarcoma Immunotherapy
- Osseointegration
- Limb Salvage and Functional Outcomes
Websites
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- UCSF Sarcoma Program Website (sarcoma.ucsf.edu)
Grants and Projects
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- Transfemoral Amputee Osseointegration Study, Department of Defense, United States Army Medical Research and Materiel Command, 2017-2022
- An Osseo-Neural Transtibial Prosthesis with Efferent-Afferent Neural Control, Department of Defense, United States Army Medical Research and Materiel Command, 2019-2022
- Identifying and enhancing the host immune response in adult soft tissue sarcoma, Musculoskeletal Tumor Society, 2019-2021
Publications (49)
Top publication keywords:
FemurProsthesis FailureAcetabulumOsseointegrationMusculoskeletal DiseasesSoft Tissue NeoplasmsSurgery, Computer-AssistedProsthesis ImplantationCancer SurvivorsRadiotherapyPrinting, Three-DimensionalSarcomaOsteosarcomaBone NeoplasmsFemoral Neoplasms
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Musculoskeletal Effects of Cancer and Cancer Treatment.
The Journal of the American Academy of Orthopaedic Surgeons 2020 Wustrack R, Rao SS, Morris CD -
Insurance impacts survival for children, adolescents, and young adults with bone and soft tissue sarcomas.
Cancer medicine 2019 Penumarthy NL, Goldsby RE, Shiboski SC, Wustrack R, Murphy P, Winestone LE -
Somatic and Germline TP53 Alterations in Second Malignant Neoplasms from Pediatric Cancer Survivors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2016 Sherborne AL, Lavergne V, Yu K, Lee L, Davidson PR, Mazor T, Smirnoff IV, Horvai AE, Loh M, DuBois SG, Goldsby RE, Neglia JP, Hammond S, Robison LL, Wustrack R, Costello JF, Nakamura AO, Shannon KM, … -
How Often Does Spindle Failure Occur in Compressive Osseointegration Endoprostheses for Oncologic Reconstruction?
Clinical orthopaedics and related research 2016 Goldman LH, Morse LJ, O'Donnell RJ, Wustrack RL -
Secondary malignant neoplasms among children, adolescents, and young adults with osteosarcoma.
Cancer 2014 Lee JS, DuBois SG, Boscardin WJ, Wustrack RL, Goldsby RE -
Predictors of new and severe vertebral fractures: results from the HORIZON Pivotal Fracture Trial.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2011 Wustrack R, Seeman E, Bucci-Rechtweg C, Burch S, Palermo L, Black DM
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Endoprosthetic Reconstruction for Proximal Humerus Tumors.
Current reviews in musculoskeletal medicine 2024 Su F, Garcia-Lopez E, Wustrack R, Lansdown DA -
Original Research: Proximal Tibia Hemiarthroplasty Reconstruction Following Resection of Malignant Bone Tumors in Skeletally Immature Patients.
Journal of the Pediatric Orthopaedic Society of North America 2024 Tyler Kelly, Lee Jae Morse, Rosanna Wustrack, Melissa Zimel -
Osteosarcoma PDX-Derived Cell Line Models for Preclinical Drug Evaluation Demonstrate Metastasis Inhibition by Dinaciclib through a Genome-Targeted Approach.
Clinical cancer research : an official journal of the American Association for Cancer Research 2024 Schott CR, Koehne AL, Sayles LC, Young EP, Luck C, Yu K, Lee AG, Breese MR, Leung SG, Xu H, Shah AT, Liu HY, Spillinger A, Behroozfard IH, Marini KD, Dinh PT, Pons Ventura MV, Vanderboon EN, Hazard FK… -
ASPSCR1-TFE3 reprograms transcription by organizing enhancer loops around hexameric VCP/p97.
Nature communications 2024 Pozner A, Li L, Verma SP, Wang S, Barrott JJ, Nelson ML, Yu JSE, Negri GL, Colborne S, Hughes CS, Zhu JF, Lambert SL, Carroll LS, Smith-Fry K, Stewart MG, Kannan S, Jensen B, John CM, Sikdar S, Liu H,… -
ASPSCR1-TFE3 reprograms transcription by organizing enhancer loops around hexameric VCP/p97.
bioRxiv : the preprint server for biology 2023 Pozner A, Verma SP, Li L, Wang S, Barrott JJ, Nelson ML, Yu JSE, Negri GL, Colborne S, Hughes CS, Zhu JF, Lambert SL, Carroll LS, Smith-Fry K, Stewart MG, Kannan S, Jensen B, Mortenson KL, John C, … -
Surgical Site Infection Is Not Associated with 1-Year Progression-Free Survival After Endoprosthetic Reconstruction for Lower-Extremity Osteosarcoma: A Secondary Analysis of PARITY Study Data.
The Journal of bone and joint surgery. American volume 2023 Jackson KJ, Sullivan CD, Zimel MN, Wustrack RL, PARITY Investigators -
A Case of Hypercalcemia from PTHrP-Producing Fibromyxoid Sarcoma Responsive to Glucocorticoid Therapy.
Calcified tissue international 2023 Niu I, Hsiao EC, Wustrack R, Wysolmerski JJ, Dann P, Masharani U -
Development and characterization of new patient-derived xenograft (PDX) models of osteosarcoma with distinct metastatic capacities.
bioRxiv : the preprint server for biology 2023 Schott CR, Koehne AL, Sayles LC, Young EP, Luck C, Yu K, Lee AG, Breese MR, Leung SG, Xu H, Shah AT, Liu HY, Spillinger A, Behroozfard IH, Marini KD, Dinh PT, Pons Ventura MAV, Vanderboon EN, Hazard … -
PSAT208 A Case of Hypercalcemia From PTHrP-Producing Fibromyxoid Sarcoma Responsive to Glucocorticoid Therapy.
Journal of the Endocrine Society 2022 Isabella Niu, Edward Hsiao, Rosanna Wustrack, John Wysolmerski, Pamela Dann, Umesh Masharani -
Survival and failure modes of the Compress® spindle and expandable distal femur endoprosthesis among pediatric patients: A multi-institutional study.
Journal of surgical oncology 2022 Tanaka KS, Andaya VR, Thorpe SW, Gundle KR, Hayden JB, Duong YC, Avedian RS, Mohler DG, Morse LJ, Zimel MN, O'Donnell RJ, Fang A, Randall RL, Tran TH, New C, Wustrack RL, other members of Study Group … -
What Are Risk Factors for and Outcomes of Late Amputation After Treatment for Lower Extremity Sarcoma: A Childhood Cancer Survivor Study Report.
Clinical orthopaedics and related research 2022 Geiger EJ, Liu W, Srivastava DK, Bernthal NM, Weil BR, Yasui Y, Ness KK, Krull KR, Goldsby RE, Oeffinger KC, Robison LL, Dieffenbach BV, Weldon CB, Gebhardt MC, Howell R, Murphy AJ, Leisenring WM, … -
Survival of Patients With Primary Osseous Malignancies of the Mobile Spine Is Associated With Access to "Standard Treatment" Protocols.
The Journal of the American Academy of Orthopaedic Surgeons 2022 Stroud SG, Geiger EJ, Lichtensztajn DY, Goldsby RE, Cheng I, Wustrack R, Theologis AA -
Malignant triton tumor in the setting of segmental neurofibromatosis: A rare case report and review of the literature.
Interdisciplinary Neurosurgery 2021 Andrew S. Jack, Christopher Witiw, Aaron Hockley, Charlotte J. Huie, Rosanna Wustrack, Line G. Jacques -
Tumor morphology and location associate with immune cell composition in pleomorphic sarcoma.
Cancer immunology, immunotherapy : CII 2021 Wustrack RL, Shao E, Sheridan J, Zimel M, Cho SJ, Horvai AE, Luong D, Kwek SS, Fong L, Okimoto RA -
Innovations in Pediatric Prosthetics.
Journal of the Pediatric Orthopaedic Society of North America 2021 Michelle J. Hall, Rosanna L. Wustrack, Donald R. Cummings, Richard I. Welling, Mary K. Kaleta, Kevin D. Koenig, Jennifer C. Laine, Sara J. Morgan -
En bloc excision of sacroiliac chondrosarcoma aided by 3D laser printed modeling and stereotactic navigation.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2021 Guinn JMV, Mayer RR, Li B, Dang ABC, Dang A, Wustrack R, Chou D -
Complete Regression of Rhabdomyosarcoma in an Adult Secondary to Postoperative Wound Infection Following Limb Salvage Surgery: A Case Report.
The Permanente journal 2020 Fang AS, Morse LJ, Wustrack R, Huber R, Pan M -
Intraoperative Radiotherapy Without External Beam Radiotherapy in the Management of Primary Soft Tissue Sarcomas of the Extremities.
International Journal of Radiation Oncology • Biology • Physics 2020 W.S. Chen, M. Lometti, R.L. Wustrack, M.N. Zimel, R.J. O'Donnell, A.E. Horvai, S.J. Cho, R.A. Okimoto, T.M. Jahan, A.R. Gottschalk, S.E. Braunstein -
Outcomes of Elderly Patients with Soft Tissue Sarcoma of the Extremities.
International Journal of Radiation Oncology • Biology • Physics 2020 J. Chew, S.A. Lloyd, R.A. Okimoto, A. Sabnis, E. Nakakura, C. Corvera, M.N. Zimel, A.E. Horvai, S.J. Cho, R.L. Wustrack, A.R. Gottschalk, R.J. O'Donnell, T.M. Jahan, S.E. Braunstein -
Risk of endoprosthetic infection and impact of health-related quality of life in patients with osteosarcoma and giant cell tumor of bone; a retrospective case-control study.
Annals of Joint 2020 Zara Butte, Kara Tanaka, Veronica Andaya, Melissa Zimel, Richard J O’Donnell, Rosanna Wustrack -
Single cell Dissection of Resistance to anti-BCMA CAR-T cell Therapy.
Clinical Lymphoma Myeloma & Leukemia 2019 Guy Ledergor, Elizabeth McCarthy, Nina Shah, Sandy Wong, Hewitt Chang, Frances Fan, Evans Shao, Lissa Gray, Alexander Cheung, Serena Kwek, Sophia Bylsma, Samuel Del Favero, Rosanna Wustrack, Matthew … -
Use of three-dimensional printing and intraoperative navigation in the surgical resection of metastatic acetabular osteosarcoma.
BMJ case reports 2019 Heunis JC, Cheah JW, Sabnis AJ, Wustrack RL -
Prospective study of percutaneous bone-anchored implants in transfemoral amputees: Brain-machine platform technology for external prosthetic control and feedback.
2013 6th International IEEE/EMBS Conference on Neural Engineering (NER) 2019 Musa B. Zaid, Rosanna L. Wustrack, Matthew Garibaldi, Erik Geiger, Veronica Andaya, Richard J. O'Donnell -
Current Concepts in Orthopaedic Care Disparities.
The Journal of the American Academy of Orthopaedic Surgeons 2018 Pandya NK, Wustrack R, Metz L, Ward D -
Methylene Blue-Guided Debridement as an Intraoperative Adjunct for the Surgical Treatment of Periprosthetic Joint Infection.
The Journal of arthroplasty 2017 Shaw JD, Miller S, Plourde A, Shaw DL, Wustrack R, Hansen EN -
Limb-Salvage Options in Growing Children with Malignant Bone Tumors of the Lower Extremity: A Critical Analysis Review.
JBJS reviews 2017 Morris CD, Wustrack RL, Levin AS -
Molecular Markers in Bone and Soft-Tissue Tumors.
JBJS reviews 2016 Wustrack R, Cooper K, Weber K -
A Resident-led Initiative Improves Screening and Treatment for Vitamin D Deficiency in Patients with Hip Fractures.
Clinical orthopaedics and related research 2016 Lansdown DA, Whitaker A, Wustrack R, Sawyer A, Hansen EN -
152 A Prospective Controlled Trial of the Effect of Surgeon Cost Scorecards on Operating Room Surgical Cost Reduction.
Neurosurgery 2016 Corinna Clio Zygourakis, Victoria Valencia, Chris Moriates, Christy Boscardin, Sereina Catschegn, Andrew Goldberg, Kevin Bozic, Kent Soo Hoo, Rosanna Wustrack, Lawrence H. Pitts, Adams Dudley, Ralph … -
Total femoral and proximal tibial compressive osseointegration.
Current Orthopaedic Practice 2016 Katharine N. Legaspi, Timothy V. Galan, Rosanna L. Wustrack, Richard J. O’Donnell -
Intraoperative radiotherapy and limb-sparing surgery in the treatment of primary, non-metastatic extremity soft tissue sarcoma.
Journal of Radiation Oncology 2015 Christopher L. Tinkle, Stuart Y. Tsuji, Vivian Weinberg, Rosanna Wustrack, Steve E. Braunstein, Daphne A. Haas-Kogan, Steven G. DuBois, Andrew Horvai, Thierry Jahan, Richard J. O’Donnell, Alexander R.… -
Intraoperative Radiotherapy in the Management of Locally Recurrent Extremity Soft Tissue Sarcoma.
Sarcoma 2015 Tinkle CL, Weinberg V, Braunstein SE, Wustrack R, Horvai A, Jahan T, O'Donnell RJ, Gottschalk AR -
Clinical features and outcomes of infants with Ewing sarcoma under 12 months of age.
Pediatric blood & cancer 2015 Wong T, Goldsby RE, Wustrack R, Cash T, Isakoff MS, DuBois SG -
Abstract P13.
Plastic & Reconstructive Surgery 2015 Carolyn J. Vaughn, Merisa L. Piper, Rosanna Wustrack, Hani Sbitany -
Risk factors for subtrochanteric and diaphyseal fractures: the study of osteoporotic fractures.
The Journal of clinical endocrinology and metabolism 2013 Napoli N, Schwartz AV, Palermo L, Jin JJ, Wustrack R, Cauley JA, Ensrud KE, Kelly M, Black DM -
Infectious, inflammatory, and metabolic diseases affecting the athlete's spine.
Clinics in sports medicine 2012 Metz LN, Wustrack R, Lovell AF, Sawyer AJ -
Are women with thicker cortices in the femoral shaft at higher risk of subtrochanteric/diaphyseal fractures? The study of osteoporotic fractures.
The Journal of clinical endocrinology and metabolism 2012 Napoli N, Jin J, Peters K, Wustrack R, Burch S, Chau A, Cauley J, Ensrud K, Kelly M, Black DM -
Aseptic failure: how does the Compress(®) implant compare to cemented stems?
Clinical orthopaedics and related research 2012 Pedtke AC, Wustrack RL, Fang AS, Grimer RJ, O'Donnell RJ -
Compartment Syndrome of Thigh.
Techniques in Orthopaedics 2012 Jeffrey MacLean, Rosanna Wustrack, Utku Kandemir -
Gluteal Compartment Syndrome.
Techniques in Orthopaedics 2012 Jeffrey MacLean, Rosanna Wustrack, Utku Kandemir -
Teriparatide, vitamin D, and calcium healed bilateral subtrochanteric stress fractures in a postmenopausal woman with a 13-year history of continuous alendronate therapy.
The Journal of clinical endocrinology and metabolism 2011 Gomberg SJ, Wustrack RL, Napoli N, Arnaud CD, Black DM -
Impact of zoledronic acid on severe vertebral fractures: Results from horizon-pivotal fracture trial.
Bone 2010 R. Wustrack, E. Seeman, C. Bucci-Rechtweg, L. Palermo, D. Black -
Thumb function and appearance in thrombocytopenia: absent radius syndrome.
The Journal of hand surgery 2007 Goldfarb CA, Wustrack R, Pratt JA, Mender A, Manske PR