Rosalie Lawrence, PhD
Postdoctoral Research Fellow
Howard Hughes Medical Instit
School of Medicine

Publications (7)

Top publication keywords:
Bacillus subtilisPhosphorylationViral ProteinsCryoelectron MicroscopyPolymerizationMolecular BiologyAllosteric RegulationEukaryotic Initiation Factor-2Bacterial ProteinsMicroscopy, FluorescenceGuanine Nucleotide Exchange FactorsStress, PhysiologicalActinsEukaryotic Initiation Factor-2BMolecular Imaging

• CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis.
  bioRxiv : the preprint server for biology 2024 Samelson AJ, Ariqat N, McKetney J, Rohanitazangi G, Bravo CP, Bose R, Travaglini KJ, Lam VL, Goodness D, Dixon G, Marzette E, Jin J, Tian R, Tse E, Abskharon R, Pan H, Carroll EC, Lawrence RE, …
• Polymer dynamics of Alp7A reveals how two critical concentrations govern assembly of dynamically unstable actin-like proteins.
  Molecular biology of the cell 2024 Petek-Seoane NA, Rodriguez J, Derman AI, Royal SG, Lord SJ, Lawrence R, Pogliano J, Mullins RD
• A helical fulcrum in eIF2B coordinates allosteric regulation of stress signaling.
  Nature chemical biology 2023 Lawrence RE, Shoemaker SR, Deal A, Sangwan S, Anand AA, Wang L, Marqusee S, Walter P
• A point mutation in the nucleotide exchange factor eIF2B constitutively activates the integrated stress response by allosteric modulation.
  eLife 2022 Boone M, Wang L, Lawrence RE, Frost A, Walter P, Schoof M
• Viral evasion of the integrated stress response through antagonism of eIF2-P binding to eIF2B.
  Nature communications 2021 Schoof M, Wang L, Cogan JZ, Lawrence RE, Boone M, Wuerth JD, Frost A, Walter P
• eIF2B conformation and assembly state regulate the integrated stress response.
  eLife 2021 Schoof M, Boone M, Wang L, Lawrence R, Frost A, Walter P
• PhotoGate microscopy to track single molecules in crowded environments.
  Nature communications 2017 Belyy V, Shih SM, Bandaria J, Huang Y, Lawrence RE, Zoncu R, Yildiz A