Romain Pirracchio, MD, PhD
Professor
Anesthesia
School of Medicine

Education & Training

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• PostDoc Biostatistics UC Berkeley 2013
• PhD Biostatistics Université Paris Diderot 2012
• MSc MPH Biostatistics Université Paris Diderot 2009
• Fellowship Critical Care Medicine Université Paris Diderot 2005
• Residency Anesthesia and Critical Care Université Paris Diderot 2003
• MD Medcine Université Paris Diderot 1999

Interests

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• Machine Learning
• clinical decision support
• Artificial Intelligence
• big data
• Perioperative Medicine
• data science
• data analysis
• Critical Care Medicine

Publications (163)

Top publication keywords:
AnesthesiologyIntensive Care UnitsAnesthesiaAirway ExtubationContinuous Positive Airway PressureHypotensionShock, SepticPneumonia, Ventilator-AssociatedTriagePropensity ScoreMachine LearningCritical IllnessRespiration, ArtificialCritical CareEmergency Medical Services

• Postoperative Delirium in a Randomized Trial of Intraoperative Norepinephrine versus Phenylephrine Infusion.
  Anesthesiology 2025 Phero A, Bokoch MP, Kothari R, Fong N, Chen D, Pirracchio R, Legrand M, Whitlock EL
• Crowd-sourced machine learning prediction of long COVID using data from the National COVID Cohort Collaborative.
  EBioMedicine 2024 Bergquist T, Loomba J, Pfaff E, Xia F, Zhao Z, Zhu Y, Mitchell E, Bhattacharya B, Shetty G, Munia T, Delong G, Tariq A, Butzin-Dozier Z, Ji Y, Li H, Coyle J, Shi S, Philips RV, Mertens A, Pirracchio R…
• Open Access Data Repository and Common Data Model for Pulse Oximeter Performance Data.
  medRxiv : the preprint server for health sciences 2024 Fong N, Lipnick MS, Behnke E, Chou Y, Elmankabadi S, Ortiz L, Almond CS, Auchus I, Burnett GW, Bisegerwa R, Conrad DR, Hendrickson CM, Hooli S, Kopotic R, Leeb G, Martin D, McCollum ED, Monk EP, Moore…
• Predicting Long COVID in the National COVID Cohort Collaborative Using Super Learner: Cohort Study.
  JMIR public health and surveillance 2024 Butzin-Dozier Z, Ji Y, Li H, Coyle J, Shi J, Phillips RV, Mertens AN, Pirracchio R, van der Laan MJ, Patel RC, Colford JM, Hubbard AE, National COVID Cohort Collaborative (N3C) Consortium
• Low-Dose Corticosteroids for Critically Ill Adults With Severe Pulmonary Infections: A Review.
  JAMA 2024 Pirracchio R, Venkatesh B, Legrand M

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• A deep learning approach for generating intracranial pressure waveforms from extracranial signals routinely measured in the intensive care unit.
  Computers in biology and medicine 2024 Nair SS, Guo A, Boen J, Aggarwal A, Chahal O, Tandon A, Patel M, Sankararaman S, Durr NJ, Azad TD, Pirracchio R, Stevens RD
• Reporting Use of AI in Research and Scholarly Publication-JAMA Network Guidance.
  JAMA 2024 Flanagin A, Pirracchio R, Khera R, Berkwits M, Hswen Y, Bibbins-Domingo K
• Harnessing machine learning for the early prediction of ventilator-associated pneumonia: A leap towards precision in critical care.
  European journal of internal medicine 2024 Garcia-Alamino JM, Pirracchio R
• Association between peripheral perfusion index and postoperative acute kidney injury in major noncardiac surgery patients receiving continuous vasopressors: a post hoc exploratory analysis of the VEGA-1 trial.
  British journal of anaesthesia 2024 Krone S, Bokoch MP, Kothari R, Fong N, Tallarico RT, Sturgess-DaPrato J, Pirracchio R, Zarbock A, Legrand M
• IntraCranial pressure prediction AlgoRithm using machinE learning (I-CARE): Training and Validation Study.
  Critical care explorations 2023 Fong N, Feng J, Hubbard A, Dang LE, Pirracchio R
• Anaesthesia Critical Care & Pain Medicine: 9 years of international publication.
  Anaesthesia, critical care & pain medicine 2023 Lefrant JY, Lorne E, Pirracchio R, Benhamou D, Milman A, Roquilly A
• Good Luck ACCPM.
  Anaesthesia, critical care & pain medicine 2023 Lefrant JY, Pirracchio R, Benhamou D, Lorne E, Roquilly A
• Management of supraventricular arrhythmias in the intensive care unit: a step in the right direction.
  Intensive care medicine 2023 Wetterslev M, Pirracchio R, Jung C
• Negativity and Positivity in the ICU: Exploratory Development of Automated Sentiment Capture in the Electronic Health Record.
  Critical care explorations 2023 Kennedy CJ, Chiu C, Chapman AC, Gologorskaya O, Farhan H, Han M, Hodgson M, Lazzareschi D, Ashana D, Lee S, Smith AK, Espejo E, Boscardin J, Pirracchio R, Cobert J
• Development of a core outcome set for ventilation trials in neurocritical care patients with acute brain injury: protocol for a Delphi consensus study of international stakeholders.
  BMJ open 2023 Digitale J, Burns G, Fong N, Boesel J, Robba C, Stevens RD, Cinotti R, Pirracchio R
• Development of a Machine Learning Model of Postoperative Acute Kidney Injury Using Non-Invasive Time-Sensitive Intraoperative Predictors.
  Bioengineering (Basel, Switzerland) 2023 Zamirpour S, Hubbard AE, Feng J, Butte AJ, Pirracchio R, Bishara A
• Postextubation Noninvasive Respiratory Support in Patients with Acute Brain Injury: Not a Panacea, but Don't Throw the Baby Out with the Bathwater!
  American journal of respiratory and critical care medicine 2023 Pirracchio R, Rabinstein AA
• Platelet transfusion before CVC placement in patients with thrombocytopenia.
  Anaesthesia, critical care & pain medicine 2023 Boulet N, Lefrant JY, Mimoz O, Roger C, Pirracchio R
• Patient-Level Meta-Analysis of Low-Dose Hydrocortisone in Adults with Septic Shock.
  NEJM evidence 2023 Pirracchio R, Annane D, Waschka AK, Lamontagne F, Arabi YM, Bollaert PE, Billot L, Du B, Briegel J, Cohen J, Finfer S, Gordon A, Hammond N, Hyvernat H, Keh D, Li Y, Liu L, Meduri GU, Mirea L, Myburgh …
• Availability of information needed to evaluate algorithmic fairness - A systematic review of publicly accessible critical care databases.
  Anaesthesia, critical care & pain medicine 2023 Fong N, Langnas E, Law T, Reddy M, Lipnick M, Pirracchio R
• Leveraging observational data to identify targeted patient populations for future randomized trials.
  Research square 2023 Lazzareschi DV, Fong N, Pirracchio R, Mathis MR, Legrand M
• Pulse contour techniques for perioperative hemodynamic monitoring: A nationwide carbon footprint and cost estimation.
  Anaesthesia, critical care & pain medicine 2023 Michard F, Futier E, Desebbe O, Biais M, Guinot PG, Leone M, Licker MJ, Molliex S, Pirracchio R, Provenchère S, Schoettker P, Zieleskiewicz L
• Intensive Care Unit activity in France from the national database between 2013 and 2019: More critically ill patients, shorter stay and lower mortality rate.
  Anaesthesia, critical care & pain medicine 2023 Boulet N, Boussere A, Mezzarobba M, Sofonea MT, Payen D, Lipman J, Laupland KB, Rello J, Lefrant JY, Muller L, Roger C, Pirracchio R, Mura T, Boudemaghe T
• Overcoming barriers in the design and implementation of clinical trials for acute kidney injury: a report from the 2020 Kidney Disease Clinical Trialists meeting.
  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2023 Lazzareschi D, Mehta RL, Dember LM, Bernholz J, Turan A, Sharma A, Kheterpal S, Parikh CR, Ali O, Schulman IH, Ryan A, Feng J, Simon N, Pirracchio R, Rossignol P, Legrand M
• Norepinephrine versus phenylephrine for treating hypotension during general anaesthesia in adult patients undergoing major noncardiac surgery: a multicentre, open-label, cluster-randomised, crossover, feasibility, and pilot trial.
  British journal of anaesthesia 2023 Legrand M, Kothari R, Fong N, Palaniappa N, Boldt D, Chen LL, Kurien P, Gabel E, Sturgess-DaPrato J, Harhay MO, Pirracchio R, Bokoch MP, VEGA-1 trial investigators
• Personalized online ensemble machine learning with applications for dynamic data streams.
  Statistics in medicine 2023 Malenica I, Phillips RV, Chambaz A, Hubbard AE, Pirracchio R, van der Laan MJ
• Database-based machine learning in sepsis deserves attention. Author's reply.
  Intensive care medicine 2023 Kalimouttou A, Pirracchio R
• Intraoperative Use of Albumin in Major Noncardiac Surgery: Incidence, Variability, and Association With Outcomes.
  Annals of surgery 2022 Lazzareschi DV, Fong N, Mavrothalassitis O, Whitlock EL, Chen CL, Chiu C, Adelmann D, Bokoch MP, Chen LL, Liu KD, Pirracchio R, Mathis MR, Legrand M, MPOG Collaborators
• Persisting high rates of omissions during anesthesia induction are decreased by utilization of a pre- & post-induction checklist.
  Anaesthesia, critical care & pain medicine 2022 Krombach JW, Zürcher C, Simon SG, Saxena S, Pirracchio R
• Building a better machine learning model of extubation for neurocritical care patients. Author's reply.
  Intensive care medicine 2022 Pirracchio R, Asehnoune K, Cinotti R
• Comprehensive analysis of coagulation factor delivery strategies in a cohort of trauma patients.
  Anaesthesia, critical care & pain medicine 2022 Roquet F, Godier A, Garrigue-Huet D, Hanouz JL, Vardon-Bounes F, Legros V, Pirracchio R, Ausset S, Duranteau J, Vigué B, Hamada SR, Traumabase® group
• Machine-learning-derived sepsis bundle of care.
  Intensive care medicine 2022 Kalimouttou A, Lerner I, Cheurfa C, Jannot AS, Pirracchio R
• Optimizing the Design and Analysis of Future AKI Trials.
  Journal of the American Society of Nephrology : JASN 2022 Legrand M, Bagshaw SM, Koyner JL, Schulman IH, Mathis MR, Bernholz J, Coca S, Gallagher M, Gaudry S, Liu KD, Mehta RL, Pirracchio R, Ryan A, Steubl D, Stockbridge N, Erlandsson F, Turan A, Wilson FP, …
• A descriptive appraisal of quality of reporting in a cohort of machine learning studies in anesthesiology.
  Anaesthesia, critical care & pain medicine 2022 Kothari R, Chiu C, Moukheiber M, Jehiro M, Bishara A, Lee C, Pirracchio R, Celi LA
• Upcoming and urgent challenges in critical care research based on COVID-19 pandemic experience.
  Anaesthesia, critical care & pain medicine 2022 Verdonk F, Feyaerts D, Badenes R, Bastarache JA, Bouglé A, Ely W, Gaudilliere B, Howard C, Kotfis K, Lautrette A, Le Dorze M, Mankidy BJ, Matthay MA, Morgan CK, Mazeraud A, Patel BV, Pattnaik R, …
• Risk factors of long term symptoms and outcomes among patients discharged after covid-19: prospective, multicentre observational study.
  BMJ medicine 2022 Legrand M, Fong N, Laouénan C, Ghosn J, Thill B, Faure K, Garot D, Goujard C, Curlier E, Resche-Rigon M, Rossignol P, Pirracchio R
• Fluids, vasopressors, and acute kidney injury after major abdominal surgery between 2015 and 2019: a multicentre retrospective analysis.
  British journal of anaesthesia 2022 Chiu C, Fong N, Lazzareschi D, Mavrothalassitis O, Kothari R, Chen LL, Pirracchio R, Kheterpal S, Domino KB, Mathis M, Legrand M
• Clinical artificial intelligence quality improvement: towards continual monitoring and updating of AI algorithms in healthcare.
  NPJ digital medicine 2022 Feng J, Phillips RV, Malenica I, Bishara A, Hubbard AE, Celi LA, Pirracchio R
• Peace, not war in Ukraine or anywhere else, please.
  Anaesthesia, critical care & pain medicine 2022 Lefrant JY, Pirracchio R, Benhamou D, Fischer MO, Njeim R, Allaouchiche B, Bastide S, Biais M, Bouvet L, Brissaud O, Brull SJ, Capdevila X, Clausen N, Cuvillon P, Dadure C, David JS, Du B, Einav S, …
• Bayesian logistic regression for online recalibration and revision of risk prediction models with performance guarantees.
  Journal of the American Medical Informatics Association : JAMIA 2022 Feng J, Gossmann A, Sahiner B, Pirracchio R
• Beyond miracles and heroes: time for an anaesthesia checklist mandate.
  Anaesthesia 2022 Saxena S, Pirracchio R, Krombach JW
• The past, the present and the future of machine learning and artificial intelligence in anesthesia and Postanesthesia Care Units (PACU).
  Minerva anestesiologica 2022 Pirracchio R
• Causal inference in case of near-violation of positivity: comparison of methods.
  Biometrical journal. Biometrische Zeitschrift 2022 Léger M, Chatton A, Le Borgne F, Pirracchio R, Lasocki S, Foucher Y
• Clinical decision support for severe trauma patients: Machine learning based definition of a bundle of care for hemorrhagic shock and traumatic brain injury.
  The journal of trauma and acute care surgery 2022 Lang E, Neuschwander A, Favé G, Abback PS, Esnault P, Geeraerts T, Harrois A, Hanouz JL, Kipnis E, Leone M, Legros V, Mellati N, Pottecher J, Hamada S, Pirracchio R, for Traumabase Group
• An international survey of adherence to Surviving Sepsis Campaign Guidelines 2016 regarding fluid resuscitation and vasopressors in the initial management of septic shock.
  Journal of critical care 2021 Bitton E, Zimmerman S, Azevedo LCP, Benhamou D, Cecconi M, De Waele JJ, Lipman J, Martin-Loeches I, Pirracchio R, Scheeren TWL, Leone M, Einav S
• One- versus two-sided statistical tests: A never-ending debate.
  Anaesthesia, critical care & pain medicine 2021 Roquet F, Pirracchio R
• 2021 adaptation of the editorial policy of Anaesthesia Critical Care and Pain Medicine (ACCPM).
  Anaesthesia, critical care & pain medicine 2021 Lefrant JY, Pirracchio R, Benhamou D, Njeim R, Ausset S, Bastide S, Biais M, Bouvet L, Brissaud O, Brull SJ, Capdevila X, Cuvillon P, Dadure C, David JS, Bin D, Fischer MO, Forget P, Fujii T, Godier A…
• Outcome of surgical patients during the first wave of the COVID-19 pandemic in US hospitals.
  British journal of anaesthesia 2021 Mavrothalassitis O, Pirracchio R, Fong N, Lazzareschi D, Sharma A, Vaughn MT, Mathis M, Legrand M
• Terror in Paris: Incidence and risk factors for infections related to high-energy ammunition injuries.
  Anaesthesia, critical care & pain medicine 2021 Birnbaum R, Bitton R, Pirracchio R, Féral-Pierssens AL, Constant AL, Dubost C, Chousterman B, Lescot T, Lortat-Jacob B, Harrois A, Abback PS, Belbachir A, Basto E, Castier Y, Laitselart P, Carli P, …
• The Physiological Deep Learner: First application of multitask deep learning to predict hypotension in critically ill patients.
  Artificial intelligence in medicine 2021 Cherifa M, Interian Y, Blet A, Resche-Rigon M, Pirracchio R
• ICU bed capacity during COVID-19 pandemic in France: From ephemeral beds to continuous and permanent adaptation.
  Anaesthesia, critical care & pain medicine 2021 Lefrant JY, Pirracchio R, Benhamou D, Dureuil B, Pottecher J, Samain E, Joannes-Boyau O, Bouaziz H
• ARDS Outcomes in Non-Research Subjects Assessed by Generalized Prospective Trial Eligibility Criteria and Adherence to Lung-Protective Ventilation.
  Respiratory care 2021 Kallet RH, Lipnick MS, Pirracchio R
• Corticosteroids for treating sepsis in children and adults.
  Emergencias : revista de la Sociedad Espanola de Medicina de Emergencias 2021 Annane D, Bellissant E, Bollaert PE, Briegel J, Keh D, Kupfer Y, Pirracchio R, Rochwerg B
• Effects of low-dose hydrocortisone and hydrocortisone plus fludrocortisone in adults with septic shock: a protocol for a systematic review and meta-analysis of individual participant data.
  BMJ open 2020 Annane D, Pirracchio R, Billot L, Waschka A, Chevret S, Cohen J, Finfer S, Gordon A, Hammond N, Myburgh J, Venkatesh B, Delaney A, ULYSSES IPDMA Collaborators
• Assessment of Machine Learning to Estimate the Individual Treatment Effect of Corticosteroids in Septic Shock.
  JAMA network open 2020 Pirracchio R, Hubbard A, Sprung CL, Chevret S, Annane D, Rapid Recognition of Corticosteroid Resistant or Sensitive Sepsis (RECORDS) Collaborators
• Automated weaning from mechanical ventilation: Results of a Bayesian network meta-analysis.
  Journal of critical care 2020 Neuschwander A, Chhor V, Yavchitz A, Resche-Rigon M, Pirracchio R
• Healthcare System Response to a Global Pandemic: Plea for a universal coordinated healthcare model.
  Anaesthesia, critical care & pain medicine 2020 Pirracchio R
• Response of US hospitals to elective surgical cases in the COVID-19 pandemic.
  British journal of anaesthesia 2020 Pirracchio R, Mavrothalassitis O, Mathis M, Kheterpal S, Legrand M
• Dynamic impact of transfusion ratios on outcomes in severely injured patients: Targeted machine learning analysis of the Pragmatic, Randomized Optimal Platelet and Plasma Ratios randomized clinical trial.
  The journal of trauma and acute care surgery 2020 Nguyen M, Pirracchio R, Kornblith LZ, Callcut R, Fox EE, Wade CE, Schreiber M, Holcomb JB, Coyle J, Cohen M, Hubbard A
• The clinical artificial intelligence department: a prerequisite for success.
  BMJ health & care informatics 2020 Cosgriff CV, Stone DJ, Weissman G, Pirracchio R, Celi LA
• Activation of the renin-angiotensin-aldosterone system is associated with Acute Kidney Injury in COVID-19.
  Anaesthesia, critical care & pain medicine 2020 Dudoignon E, Moreno N, Deniau B, Coutrot M, Longer R, Amiot Q, Mebazaa A, Pirracchio R, Depret F, Legrand M
• Accuracy of a multiparametric score based on pulse wave analysis for prediction of fluid responsiveness: ancillary analysis of an observational study.
  Canadian journal of anaesthesia = Journal canadien d'anesthesie 2020 Neuschwander A, Barthélémy R, Ditchi D, Dramé F, Redouté M, Stern J, Cholley B, Mebazaa A, Chousterman BG, Pirracchio R
• Extracorporeal cardiopulmonary resuscitation in out-of-hospital cardiac arrest: a registry study.
  European heart journal 2020 Bougouin W, Dumas F, Lamhaut L, Marijon E, Carli P, Combes A, Pirracchio R, Aissaoui N, Karam N, Deye N, Sideris G, Beganton F, Jost D, Cariou A, Jouven X, Sudden Death Expertise Center investigators
• Is Extracorporeal Membrane Oxygenation Withdrawal a Safe Option After Double-Lung Transplantation?
  The Annals of thoracic surgery 2020 Fessler J, Sage E, Roux A, Feliot E, Gayat E, Pirracchio R, Parquin F, Cerf C, Fischler M, Le Guen M
• Effect of fibrinogen concentrate administration on early mortality in traumatic hemorrhagic shock: A propensity score analysis.
  The journal of trauma and acute care surgery 2020 Hamada SR, Pirracchio R, Beauchesne J, Benlaldj MN, Meaudre E, Leone M, Pottecher J, Abback PS, Gauss T, Boutonnet M, Cook F, Garrigue D, Lesache F, Julie J, Rouquette A, Duranteau J
• Prediction of an Acute Hypotensive Episode During an ICU Hospitalization With a Super Learner Machine-Learning Algorithm.
  Anesthesia and analgesia 2020 Cherifa M, Blet A, Chambaz A, Gayat E, Resche-Rigon M, Pirracchio R
• Haemodynamic management during hyperthermic intraperitoneal chemotherapy: A systematic review.
  Anaesthesia, critical care & pain medicine 2020 Bezu L, Raineau M, Deloménie M, Cholley B, Pirracchio R
• Modified 4T score for heparin-induced thrombocytopenia diagnosis in VA-ECMO patients.
  Intensive care medicine 2020 Renou A, Neuschwander A, Kimmoun A, Brodie D, Pirracchio R, HIT-ECMO Study Group
• Should we ban hydroethyl starches from the operating theatre? PRO.
  Anaesthesia, critical care & pain medicine 2020 Legrand M, Pirracchio R
• Performance of propensity score matching to estimate causal effects in small samples.
  Statistical methods in medical research 2020 Andrillon A, Pirracchio R, Chevret S
• Expert-augmented machine learning.
  Proceedings of the National Academy of Sciences of the United States of America 2020 Gennatas ED, Friedman JH, Ungar LH, Pirracchio R, Eaton E, Reichmann LG, Interian Y, Luna JM, Simone CB, Auerbach A, Delgado E, van der Laan MJ, Solberg TD, Valdes G
• Prehospital triage of acute aortic syndrome using a machine learning algorithm.
  The British journal of surgery 2020 Duceau B, Alsac JM, Bellenfant F, Mailloux A, Champigneulle B, Favé G, Neuschwander A, El Batti S, Cholley B, Achouh P, Pirracchio R
• Association between hydroxocobalamin administration and acute kidney injury after smoke inhalation: a multicenter retrospective study.
  Critical care (London, England) 2019 Dépret F, Hoffmann C, Daoud L, Thieffry C, Monplaisir L, Creveaux J, Annane D, Parmentier E, Mathieu D, Wiramus S, Demeure DIt Latte D, Kpodji A, Textoris J, Robin F, Klouche K, Pontis E, Schnell G, …
• Corticosteroids for treating sepsis in children and adults.
  The Cochrane database of systematic reviews 2019 Annane D, Bellissant E, Bollaert PE, Briegel J, Keh D, Kupfer Y, Pirracchio R, Rochwerg B
• What every intensivist should know about Big Data and targeted machine learning in the intensive care unit.
  Revista Brasileira de terapia intensiva 2019 Cherifa M, Pirracchio R
• Association of Early, High Plasma-to-Red Blood Cell Transfusion Ratio With Mortality in Adults With Severe Bleeding After Trauma.
  JAMA network open 2019 Roquet F, Neuschwander A, Hamada S, Favé G, Follin A, Marrache D, Cholley B, Pirracchio R, Traumabase Group
• Anaesthesia-specific checklists: A systematic review of impact.
  Anaesthesia, critical care & pain medicine 2019 Saxena S, Krombach JW, Nahrwold DA, Pirracchio R
• Early changes in diaphragmatic function evaluated using ultrasound in cardiac surgery patients: a cohort study.
  Journal of clinical monitoring and computing 2019 Tralhão A, Cavaleiro P, Arrigo M, Lopes JP, Lebrun M, Rivas-Lasarte M, Le Pimpec-Barthes F, Latrémouille C, Achouh P, Pirracchio R, Cholley B
• Intraoperative management of brain-dead organ donors by anesthesiologists during an organ procurement procedure: results from a French survey.
  BMC anesthesiology 2019 Champigneulle B, Neuschwander A, Bronchard R, Favé G, Josserand J, Lebas B, Bastien O, Pirracchio R, SFAR research network
• Impact of triage-to-admission time on patient outcome in European intensive care units: A prospective, multi-national study.
  Journal of critical care 2019 Stohl S, Sprung CL, Lippert A, Pirracchio R, Artigas A, Iapichino G, Harris S, Pezzi A, Schlesinger M
• Neutropenic Enterocolitis in Critically Ill Patients: Spectrum of the Disease and Risk of Invasive Fungal Disease.
  Critical care medicine 2019 Duceau B, Picard M, Pirracchio R, Wanquet A, Pène F, Merceron S, Mokart D, Moreau AS, Lengliné E, Canet E, Lemiale V, Mariotte E, Azoulay E, Zafrani L
• Prognostic value of the PaO2 /FiO2 ratio determined at the end-surgery stage of a double-lung transplantation.
  Clinical transplantation 2019 Fessler J, Thes J, Pirracchio R, Godement M, Sage E, Roux A, Parquin F, Cerf C, Fischler M, Le Guen M
• Should we still prescribe Levosimendan for low cardiac output after cardiac surgery? Perhaps in the good patients!
  Anaesthesia, critical care & pain medicine 2019 Pirracchio R
• The Fragility and Reliability of Conclusions of Anesthesia and Critical Care Randomized Trials With Statistically Significant Findings: A Systematic Review.
  Critical care medicine 2019 Grolleau F, Collins GS, Smarandache A, Pirracchio R, Gakuba C, Boutron I, Busse JW, Devereaux PJ, Le Manach Y
• Suicide attempts by jumping and length of stay in general hospital: A retrospective study of 225 patients.
  Journal of psychosomatic research 2019 Todorov L, Vulser H, Pirracchio R, Thauvin I, Radtchenko A, Vidal J, Guigui P, Limosin F, Lemogne C
• Heterogeneity in Intensive Care: Low Severity Does Not Mean Low Risk!
  Anesthesiology 2019 Pirracchio R, Gropper MA
• Monitoring haemodynamic response to fluid-challenge in ICU: comparison of pressure recording analytical method and oesophageal Doppler: A prospective observational study.
  European journal of anaesthesiology 2019 Barthélémy R, Neuschwander A, Dramé F, Redouté M, Ditchi D, Stern J, Mebazaa A, Pirracchio R, Chousterman BG
• Weaning from veno-arterial extra-corporeal membrane oxygenation: which strategy to use?
  Annals of cardiothoracic surgery 2019 Ortuno S, Delmas C, Diehl JL, Bailleul C, Lancelot A, Naili M, Cholley B, Pirracchio R, Aissaoui N
• Inhaled nitric oxide dependency at the end of double-lung transplantation: a boosted propensity score cohort analysis.
  Transplant international : official journal of the European Society for Organ Transplantation 2018 Fessler J, Godement M, Pirracchio R, Marandon JY, Thes J, Sage E, Roux A, Parquin F, Cerf C, Fischler M, Le Guen M
• Impact of an Acinetobacter baumannii outbreak on kidney events in a burn unit: A targeted machine learning analysis.
  American journal of infection control 2018 Vauchel T, Pirracchio R, Chaussard M, Lafaurie M, Rouveau M, Rousseau C, Benyamina M, Soussi S, Dépret F, Ferry A, Oueslati H, Chaouat M, Mimoun M, Jarlier V, Moreno N, Mebazaa A, Legrand M
• Correction to: Epinephrine and short-term survival in cardiogenic shock: an individual data meta-analysis of 2583 patients.
  Intensive care medicine 2018 Léopold V, Gayat E, Pirracchio R, Spinar J, Parenica J, Tarvasmäki T, Lassus J, Harjola VP, Champion S, Zannad F, Valente S, Urban P, Chua HR, Bellomo R, Popovic B, Ouweneel DM, Henriques JPS, Simonis…
• Big data and targeted machine learning in action to assist medical decision in the ICU.
  Anaesthesia, critical care & pain medicine 2018 Pirracchio R, Cohen MJ, Malenica I, Cohen J, Chambaz A, Cannesson M, Lee C, Resche-Rigon M, Hubbard A, ACTERREA Research Group
• Determining the editorial policy of Anaesthesia Critical Care and Pain Medicine (ACCPM).
  Anaesthesia, critical care & pain medicine 2018 Lefrant JY, Lorne E, Asehnoune K, Ausset S, Beaulieu P, Biais M, Brichant JF, Charbit B, Constantin JM, Cuvillon P, Dadure C, Dahmani S, David JS, Fuchs-Buder T, Geeraerts T, Godier A, Hanouz JL, …
• First description of successful use of zone 1 resuscitative endovascular balloon occlusion of the aorta in the prehospital setting.
  Resuscitation 2018 Lamhaut L, Qasim Z, Hutin A, Dagron C, Orsini JP, Haegel A, Perkins Z, Pirracchio R, Carli P
• Understanding Left Ventricular Assist Devices.
  Blood purification 2018 Aissaoui N, Jouan J, Gourjault M, Diebold B, Ortuno S, Hamdan A, Latremouille C, Pirracchio R, Morshuis M
• Concordance of common data elements for assessment of subjective cognitive complaints after mild-traumatic brain injury: a TRACK-TBI Pilot Study.
  Brain injury 2018 Ngwenya LB, Gardner RC, Yue JK, Burke JF, Ferguson AR, Huang MC, Winkler EA, Pirracchio R, Satris GG, Yuh EL, Mukherjee P, Valadka AB, Okonkwo DO, Manley GT
• Epinephrine and short-term survival in cardiogenic shock: an individual data meta-analysis of 2583 patients.
  Intensive care medicine 2018 Léopold V, Gayat E, Pirracchio R, Spinar J, Parenica J, Tarvasmäki T, Lassus J, Harjola VP, Champion S, Zannad F, Valente S, Urban P, Chua HR, Bellomo R, Popovic B, Ouweneel DM, Henriques JPS, Simonis…
• Strategic proposal for a national trauma system in France.
  Anaesthesia, critical care & pain medicine 2018 Gauss T, Balandraud P, Frandon J, Abba J, Ageron FX, Albaladejo P, Arvieux C, Barbois S, Bijok B, Bobbia X, Charbit J, Cook F, David JS, Maurice GS, Duranteau J, Garrigue D, Gay E, Geeraerts T, Ghelfi…
• Development and validation of a pre-hospital "Red Flag" alert for activation of intra-hospital haemorrhage control response in blunt trauma.
  Critical care (London, England) 2018 Hamada SR, Rosa A, Gauss T, Desclefs JP, Raux M, Harrois A, Follin A, Cook F, Boutonnet M, Traumabase® Group, Attias A, Ausset S, Boutonnet M, Dhonneur G, Duranteau J, Langeron O, Paugam-Burtz C, …
• Major traumatic complications after out-of-hospital cardiac arrest: Insights from the Parisian registry.
  Resuscitation 2018 Champigneulle B, Haruel PA, Pirracchio R, Dumas F, Geri G, Arnaout M, Paul M, Pène F, Mira JP, Bougouin W, Cariou A
• Association between continuous hyperosmolar therapy and survival in patients with traumatic brain injury - a multicentre prospective cohort study and systematic review.
  Critical care (London, England) 2017 Asehnoune K, Lasocki S, Seguin P, Geeraerts T, Perrigault PF, Dahyot-Fizelier C, Paugam Burtz C, Cook F, Demeure Dit Latte D, Cinotti R, Mahe PJ, Fortuit C, Pirracchio R, Feuillet F, Sébille V, …
• Improved Survival After Implementation of a Large-Scale Regional Dedicated Aortic Network.
  Journal of the American College of Cardiology 2017 Duceau B, Alsac JM, Bellenfant F, Mailloux A, Chhor V, Lagrange A, El Batti S, Cholley B, Achouh P, Pirracchio R
• Veno-arterial-ECMO in the intensive care unit: From technical aspects to clinical practice.
  Anaesthesia, critical care & pain medicine 2017 Le Gall A, Follin A, Cholley B, Mantz J, Aissaoui N, Pirracchio R
• Undetectable haptoglobin is associated with major adverse kidney events in critically ill burn patients.
  Critical care (London, England) 2017 Dépret F, Dunyach C, De Tymowski C, Chaussard M, Bataille A, Ferry A, Moreno N, Cupaciu A, Soussi S, Benyamina M, Mebazaa A, Serror K, Chaouat M, Garnier JP, Pirracchio R, Legrand M, PRONOBURN group
• Effect of Levosimendan on Low Cardiac Output Syndrome in Patients With Low Ejection Fraction Undergoing Coronary Artery Bypass Grafting With Cardiopulmonary Bypass: The LICORN Randomized Clinical Trial.
  JAMA 2017 Cholley B, Caruba T, Grosjean S, Amour J, Ouattara A, Villacorta J, Miguet B, Guinet P, Lévy F, Squara P, Aït Hamou N, Carillion A, Boyer J, Boughenou MF, Rosier S, Robin E, Radutoiu M, Durand M, …
• Emergency department blood alcohol level associates with injury factors and six-month outcome after uncomplicated mild traumatic brain injury.
  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2017 Yue JK, Ngwenya LB, Upadhyayula PS, Deng H, Winkler EA, Burke JF, Lee YM, Robinson CK, Ferguson AR, Lingsma HF, Cnossen MC, Pirracchio R, Korley FK, Vassar MJ, Yuh EL, Mukherjee P, Gordon WA, Valadka …
• Selective Serotonin Reuptake Inhibitors for Treating Neurocognitive and Neuropsychiatric Disorders Following Traumatic Brain Injury: An Evaluation of Current Evidence.
  Brain sciences 2017 Yue JK, Burke JF, Upadhyayula PS, Winkler EA, Deng H, Robinson CK, Pirracchio R, Suen CG, Sharma S, Ferguson AR, Ngwenya LB, Stein MB, Manley GT, Tarapore PE
• Risk factors of percutaneous cannulation failure by intensivists for veno-arterial extracorporeal life support for refractory cardiac arrest.
  Intensive care medicine 2017 Chhor V, Follin A, Joachim J, Champigneulle B, Chatelon J, Favé G, Neuschwander A, Mantz J, Pirracchio R
• The Balance Super Learner: A robust adaptation of the Super Learner to improve estimation of the average treatment effect in the treated based on propensity score matching.
  Statistical methods in medical research 2016 Pirracchio R, Carone M
• A decade of hospital-based violence intervention: Benefits and shortcomings.
  The journal of trauma and acute care surgery 2016 Juillard C, Cooperman L, Allen I, Pirracchio R, Henderson T, Marquez R, Orellana J, Texada M, Dicker RA
• Feasibility and Predictive Value of Ultrasound Assessment of the Gastric Residual Volume in Surgical Critically Ill Patients: A Pilot Study.
  Critical care medicine 2016 Chatelon J, Bourillon C, Darmon H, Carbonne H, Chhor V, Follin A, Cholley B, Guinvarc'h A, Mantz J, Pirracchio R
• Circadian variability of the initial Glasgow Coma Scale score in traumatic brain injury patients.
  Neurobiology of sleep and circadian rhythms 2016 Yue JK, Robinson CK, Winkler EA, Upadhyayula PS, Burke JF, Pirracchio R, Suen CG, Deng H, Ngwenya LB, Dhall SS, Manley GT, Tarapore PE
• Effect of cricoid pressure on laryngeal view during prehospital tracheal intubation: a propensity-based analysis.
  Emergency medicine journal : EMJ 2016 Caruana E, Chevret S, Pirracchio R
• Comparison of distribution of lung aeration measured with EIT and CT in spontaneously breathing, awake patients1.
  Bio-medical materials and engineering 2016 Radke OC, Schneider T, Braune A, Pirracchio R, Fischer F, Koch T
• Impact of Resident Rotations on Critically Ill Patient Outcomes: Results of a French Multicenter Observational Study.
  PloS one 2016 Chousterman BG, Pirracchio R, Guidet B, Aegerter P, Mentec H, CUB-REA network
• Collaborative targeted maximum likelihood estimation for variable importance measure: Illustration for functional outcome prediction in mild traumatic brain injuries.
  Statistical methods in medical research 2016 Pirracchio R, Yue JK, Manley GT, van der Laan MJ, Hubbard AE, TRACK-TBI Investigators including Wayne A Gordon, Hester F Lingsma, Andrew IR Maas, Pratik Mukherjee
• Screening for Post-Traumatic Stress Disorder in a Civilian Emergency Department Population with Traumatic Brain Injury.
  Journal of neurotrauma 2016 Haarbauer-Krupa J, Taylor CA, Yue JK, Winkler EA, Pirracchio R, Cooper SR, Burke JF, Stein MB, Manley GT
• Tree-based algorithm for prehospital triage of polytrauma patients.
  Injury 2016 Follin A, Jacqmin S, Chhor V, Bellenfant F, Robin S, Guinvarc'h A, Thomas F, Loeb T, Mantz J, Pirracchio R
• Will Xenon Be a Valuable Addition in Perioperative and Critical Care Settings?
  Anesthesia and analgesia 2016 Maze M, Pirracchio R
• What's new in the quantification of causal effects from longitudinal cohort studies: a brief introduction to marginal structural models for intensivists.
  Intensive care medicine 2015 Bailly S, Pirracchio R, Timsit JF
• A new weighted balance measure helped to select the variables to be included in a propensity score model.
  Journal of clinical epidemiology 2015 Caruana E, Chevret S, Resche-Rigon M, Pirracchio R
• Tracheal intubation related complications in the prehospital setting.
  Emergency medicine journal : EMJ 2015 Caruana E, Duchateau FX, Cornaglia C, Devaud ML, Pirracchio R
• Improving ultrasonic measurement of diaphragmatic excursion after cardiac surgery using the anatomical M-mode: a randomized crossover study.
  Intensive care medicine 2015 Pasero D, Koeltz A, Placido R, Fontes Lima M, Haun O, Rienzo M, Marrache D, Pirracchio R, Safran D, Cholley B
• Improving propensity score estimators' robustness to model misspecification using super learner.
  American journal of epidemiology 2014 Pirracchio R, Petersen ML, van der Laan M
• Determinants of Transcutaneous Ear Lobe CO2 Tension (PtCO2) at 37°C During On-Pump Cardiac Surgery.
  Journal of cardiothoracic and vascular anesthesia 2014 Neuschwander A, Couffin S, Huynh TM, Cholley B, de Villechenon GP, Achouh P, Fabiani JN, Safran D, Pirracchio R
• Extracorporeal life support (ECLS) for refractory cardiac arrest after drowning: an 11-year experience.
  Resuscitation 2014 Champigneulle B, Bellenfant-Zegdi F, Follin A, Lebard C, Guinvarch A, Thomas F, Pirracchio R, Journois D
• Mortality prediction in intensive care units with the Super ICU Learner Algorithm (SICULA): a population-based study.
  The Lancet. Respiratory medicine 2014 Pirracchio R, Petersen ML, Carone M, Rigon MR, Chevret S, van der Laan MJ
• Hypothermia for bacterial meningitis.
  JAMA 2014 Pirracchio R, Journois D
• Recalibrating our prediction models in the ICU: time to move from the abacus to the computer.
  Intensive care medicine 2014 Pirracchio R, Ranzani OT
• Propensity score estimators for the average treatment effect and the average treatment effect on the treated may yield very different estimates.
  Statistical methods in medical research 2013 Pirracchio R, Carone M, Rigon MR, Caruana E, Mebazaa A, Chevret S
• Incidence, risk factors and prediction of post-operative acute kidney injury following cardiac surgery for active infective endocarditis: an observational study.
  Critical care (London, England) 2013 Legrand M, Pirracchio R, Rosa A, Petersen ML, Van der Laan M, Fabiani JN, Fernandez-gerlinger MP, Podglajen I, Safran D, Cholley B, Mainardi JL
• Reply to short-term mortality and CPAP in acute cardiac pulmonary edema: how and what can we be expecting?
  Journal of cardiac failure 2013 Pirracchio R, Mebazaa A
• Do simple screening statistical tools help to detect reporting bias?
  Annals of intensive care 2013 Pirracchio R, Resche-Rigon M, Chevret S, Journois D
• The effectiveness of inodilators in reducing short term mortality among patient with severe cardiogenic shock: a propensity-based analysis.
  PloS one 2013 Pirracchio R, Parenica J, Resche Rigon M, Chevret S, Spinar J, Jarkovsky J, Zannad F, Alla F, Mebazaa A, GREAT network
• [Usefulness of Bispectral Index (BIS) monitoring for early detection of cerebral hypoperfusions].
  Annales francaises d'anesthesie et de reanimation 2013 Nebout S, Wagner M, Saint-Maurice JP, Houdart E, Madadaki C, Borsali A, Pirracchio R
• Simple screening statistical tools to detect reporting bias: when should we ask for raw data?
  Critical care (London, England) 2013 Pirracchio R, Resche-Rigon M, Chevret S, Journois D
• Continuous positive airway pressure (CPAP) may not reduce short-term mortality in cardiogenic pulmonary edema: a propensity-based analysis.
  Journal of cardiac failure 2013 Pirracchio R, Resche Rigon M, Mebazaa A, Zannad F, Alla F, Chevret S
• Estimating the treatment effect from non-randomized studies: The example of reduced intensity conditioning allogeneic stem cell transplantation in hematological diseases.
  BMC blood disorders 2012 Resche-Rigon M, Pirracchio R, Robin M, De Latour RP, Sibon D, Ades L, Ribaud P, Fermand JP, Thieblemont C, Socié G, Chevret S
• Evaluation of the propensity score methods for estimating marginal odds ratios in case of small sample size.
  BMC medical research methodology 2012 Pirracchio R, Resche-Rigon M, Chevret S
• The Eldicus prospective, observational study of triage decision making in European intensive care units. Part II: intensive care benefit for the elderly.
  Critical care medicine 2012 Sprung CL, Artigas A, Kesecioglu J, Pezzi A, Wiis J, Pirracchio R, Baras M, Edbrooke DL, Pesenti A, Bakker J, Hargreaves C, Gurman G, Cohen SL, Lippert A, Payen D, Corbella D, Iapichino G
• The Eldicus prospective, observational study of triage decision making in European intensive care units: part I--European Intensive Care Admission Triage Scores.
  Critical care medicine 2012 Sprung CL, Baras M, Iapichino G, Kesecioglu J, Lippert A, Hargreaves C, Pezzi A, Pirracchio R, Edbrooke DL, Pesenti A, Bakker J, Gurman G, Cohen SL, Wiis J, Payen D, Artigas A
• [Out-of-hospital assessment of elderly patients' preference for ICU care].
  Annales francaises d'anesthesie et de reanimation 2011 Pirracchio R, Gallula S, Broche C, Ogereau C, Payen D
• [From iatrogenesis to medical errors: review of the literature and analytical approach].
  Annales francaises d'anesthesie et de reanimation 2011 Chousterman B, Pirracchio R
• Benefits of ICU admission in critically ill patients: whether instrumental variable methods or propensity scores should be used.
  BMC medical research methodology 2011 Pirracchio R, Sprung C, Payen D, Chevret S
• Should We Monitor ScVO(2) in Critically Ill Patients?
  Cardiology research and practice 2011 Nebout S, Pirracchio R
• Utility of time-dependent inverse-probability-of-treatment weights to analyze observational cohorts in the intensive care unit.
  Journal of clinical epidemiology 2011 Pirracchio R, Sprung CL, Payen D, Chevret S
• Arterial catheter-related bloodstream infections: results of an 8-year survey in a surgical intensive care unit.
  Critical care medicine 2011 Pirracchio R, Legrand M, Rigon MR, Mateo J, Lukaszewicz AC, Mebazaa A, Raskine L, Le Pors MJ, Payen D
• Implications of ICU triage decisions on patient mortality: a cost-effectiveness analysis.
  Critical care (London, England) 2011 Edbrooke DL, Minelli C, Mills GH, Iapichino G, Pezzi A, Corbella D, Jacobs P, Lippert A, Wiis J, Pesenti A, Patroniti N, Pirracchio R, Payen D, Gurman G, Bakker J, Kesecioglu J, Hargreaves C, Cohen SL…
• Neurosurgery and elderly: analysis through the years.
  Neurosurgical review 2011 Chibbaro S, Di Rocco F, Makiese O, Mirone G, Marsella M, Lukaszewicz AC, Vicaut E, Turner B, Hamdi S, Spiriev T, Di Emidio P, Pirracchio R, Payen D, George B, Bresson D
• One-year outcome after neurosurgery for intracranial tumor in elderly patients.
  Journal of neurosurgical anesthesiology 2010 Pirracchio R, Resche-Rigon M, Bresson D, Basta B, Welschbillig S, Heyer L, Kechiche H, Madadaki C, Chollet A, Lukaszewicz AC, Mebazaa A, George B, Payen D
• Propensity scores in intensive care and anaesthesiology literature: a systematic review.
  Intensive care medicine 2010 Gayat E, Pirracchio R, Resche-Rigon M, Mebazaa A, Mary JY, Porcher R
• Fluid resuscitation does not improve renal oxygenation during hemorrhagic shock in rats.
  Anesthesiology 2010 Legrand M, Mik EG, Balestra GM, Lutter R, Pirracchio R, Payen D, Ince C
• Cardiac troponin and skeletal muscle oxygenation in severe post-partum haemorrhage.
  Critical care (London, England) 2009 Heyer L, Mebazaa A, Gayat E, Resche-Rigon M, Rabuel C, Rezlan E, Lukascewicz AC, Madadaki C, Pirracchio R, Schurando P, Morel O, Fargeaudou Y, Payen D
• Monocytic HLA-DR expression in intensive care patients: interest for prognosis and secondary infection prediction.
  Critical care medicine 2009 Lukaszewicz AC, Grienay M, Resche-Rigon M, Pirracchio R, Faivre V, Boval B, Payen D
• Use of B-type natriuretic peptide in critically ill patients.
  Biomarkers in medicine 2009 Pirracchio R, Salem R, Mebazaa A
• Can bacteriological upper airway samples obtained at intensive care unit admission guide empiric antibiotherapy for ventilator-associated pneumonia?
  Critical care medicine 2009 Pirracchio R, Mateo J, Raskine L, Rigon MR, Lukaszewicz AC, Mebazaa A, Hammitouche Y, Sanson-Le Pors MJ, Payen D
• Tako Tsubo cardiomyopathy in a patient with multiple trauma.
  Resuscitation 2009 Vergez M, Pirracchio R, Mateo J, Payen D, Cholley B
• The use of natriuretic peptides in the intensive care unit.
  Current opinion in critical care 2008 Pirracchio R, Logeart D, Noveanu M, Mebazaa A, Mueller C
• Impaired plasma B-type natriuretic peptide clearance in human septic shock.
  Critical care medicine 2008 Pirracchio R, Deye N, Lukaszewicz AC, Mebazaa A, Cholley B, Matéo J, Mégarbane B, Launay JM, Peynet J, Baud F, Payen D
• A randomized study of out-of-hospital continuous positive airway pressure for acute cardiogenic pulmonary oedema: physiological and clinical effects.
  European heart journal 2007 Plaisance P, Pirracchio R, Berton C, Vicaut E, Payen D
• The impedance threshold valve for adult cardiopulmonary resuscitation: a review of the literature.
  Current opinion in critical care 2007 Pirracchio R, Payen D, Plaisance P
• Diastolic heart failure in anaesthesia and critical care.
  British journal of anaesthesia 2007 Pirracchio R, Cholley B, De Hert S, Solal AC, Mebazaa A
• Feasibility of closed-loop titration of propofol guided by the Bispectral Index for general anaesthesia induction: a prospective randomized study.
  European journal of anaesthesiology 2006 Liu N, Chazot T, Trillat B, Pirracchio R, Law-Koune JD, Barvais L, Fischler M