Roly Gosling, PhD, MS, MD
Professor
Epidemiology & Biostatistics
School of Medicine

We have a broad range of activities from desk based research producing advocacy and summary materials to highlight the substantial progress of malaria control and elimination world wide, to field based research exploring active surveillance strategies, efficacy of drug based transmission interventions, costing studies of elimination programs and more qualitative research such as case studies. The program also supports countries by supporting regional networks of countries to eliminate malaria (the Asia Pacific Malaria Elimination Network, APMEN and the Eliminating 8, E8 in southern Africa).

Dr Gosling is based in Namibia until 2020.

We do have opportunities to send students to support field research studies.

• Developing an expanded vector control toolbox for malaria elimination.
  BMJ global health 2017 Killeen GF, Tatarsky A, Diabate A, Chaccour CJ, Marshall JM, Okumu FO, Brunner S, Newby G, Williams YA, Malone D, Tusting LS, Gosling RD
• The central role of national programme management for the achievement of malaria elimination: a cross case-study analysis of nine malaria programmes.
  Malaria journal 2016 Smith Gueye C, Newby G, Tulloch J, Slutsker L, Tanner M, Gosling RD
• Development of a pharmacovigilance safety monitoring tool for the rollout of single low-dose primaquine and artemether-lumefantrine to treat Plasmodium falciparum infections in Swaziland: a pilot study.
  Malaria journal 2016 Poirot E, Soble A, Ntshalintshali N, Mwandemele A, Mkhonta N, Malambe C, Vilakati S, Pan S, Darteh S, Maphalala G, Brown J, Hwang J, Pace C, Stergachis A, Vittinghoff E, Kunene S, Gosling R
• Strategies and approaches to vector control in nine malaria-eliminating countries: a cross-case study analysis.
  Malaria journal 2016 Smith Gueye C, Newby G, Gosling RD, Whittaker MA, Chandramohan D, Slutsker L, Tanner M
• Risks of Hemolysis in Glucose-6-Phosphate Dehydrogenase Deficient Infants Exposed to Chlorproguanil-Dapsone, Mefloquine and Sulfadoxine-Pyrimethamine as Part of Intermittent Presumptive Treatment of Malaria in Infants.
  PloS one 2015 Poirot E, Vittinghoff E, Ishengoma D, Alifrangis M, Carneiro I, Hashim R, Baraka V, Mosha J, Gesase S, Chandramohan D, Gosling R
• The independent effect of living in malaria hotspots on future malaria infection: an observational study from Misungwi, Tanzania.
  Malaria journal 2014 Mosha JF, Sturrock HJ, Brown JM, Hashim R, Kibiki G, Chandramohan D, Gosling RD
• Fine-scale malaria risk mapping from routine aggregated case data.
  Malaria journal 2014 Sturrock HJ, Cohen JM, Keil P, Tatem AJ, Le Menach A, Ntshalintshali NE, Hsiang MS, Gosling RD
• Hot spot or not: a comparison of spatial statistical methods to predict prospective malaria infections.
  Malaria journal 2014 Mosha JF, Sturrock HJ, Greenwood B, Sutherland CJ, Gadalla NB, Atwal S, Hemelaar S, Brown JM, Drakeley C, Kibiki G, Bousema T, Chandramohan D, Gosling RD
• Targeting imported malaria through social networks: a potential strategy for malaria elimination in Swaziland.
  Malaria journal 2013 Koita K, Novotny J, Kunene S, Zulu Z, Ntshalintshali N, Gandhi M, Gosling R
• The economic benefits of malaria elimination: do they include increases in tourism?
  Malaria journal 2012 Modrek S, Liu J, Gosling R, Feachem RG
• IgG responses to Anopheles gambiae salivary antigen gSG6 detect variation in exposure to malaria vectors and disease risk.
  PloS one 2012 Stone W, Bousema T, Jones S, Gesase S, Hashim R, Gosling R, Carneiro I, Chandramohan D, Theander T, Ronca R, Modiano D, Arcà B, Drakeley C
• Hitting hotspots: spatial targeting of malaria for control and elimination.
  PLoS medicine 2012 Bousema T, Griffin JT, Sauerwein RW, Smith DL, Churcher TS, Takken W, Ghani A, Drakeley C, Gosling R
• Malaria control in Bhutan: case study of a country embarking on elimination.
  Malaria journal 2012 Yangzom T, Gueye CS, Namgay R, Galappaththy GN, Thimasarn K, Gosling R, Murugasampillay S, Dev V
• A national policy for malaria elimination in Swaziland: a first for sub-Saharan Africa.
  Malaria journal 2011 Kunene S, Phillips AA, Gosling RD, Kandula D, Novotny JM
• The role of antimalarial treatment in the elimination of malaria.
  Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2011 Gosling RD, Okell L, Mosha J, Chandramohan D
• A cluster-randomized trial of mass drug administration with a gametocytocidal drug combination to interrupt malaria transmission in a low endemic area in Tanzania.
  Malaria journal 2011 Shekalaghe SA, Drakeley C, van den Bosch S, ter Braak R, van den Bijllaardt W, Mwanziva C, Semvua S, Masokoto A, Mosha F, Teelen K, Hermsen R, Okell L, Gosling R, Sauerwein R, Bousema T
• Adjusting for heterogeneity of malaria transmission in longitudinal studies.
  The Journal of infectious diseases 2011 Bousema T, Kreuels B, Gosling R
• Modelling the protective efficacy of alternative delivery schedules for intermittent preventive treatment of malaria in infants and children.
  PloS one 2011 Cairns M, Ghani A, Okell L, Gosling R, Carneiro I, Anto F, Asoala V, Owusu-Agyei S, Greenwood B, Chandramohan D, Milligan P
• Protective efficacy of intermittent preventive treatment of malaria in infants (IPTi) using sulfadoxine-pyrimethamine and parasite resistance.
  PloS one 2010 Griffin JT, Cairns M, Ghani AC, Roper C, Schellenberg D, Carneiro I, Newman RD, Grobusch MP, Greenwood B, Chandramohan D, Gosling RD
• The cost-effectiveness of intermittent preventive treatment for malaria in infants in Sub-Saharan Africa.
  PloS one 2010 Conteh L, Sicuri E, Manzi F, Hutton G, Obonyo B, Tediosi F, Biao P, Masika P, Matovu F, Otieno P, Gosling RD, Hamel M, Odhiambo FO, Grobusch MP, Kremsner PG, Chandramohan D, Aponte JJ, Egan A, …
• Identification of hot spots of malaria transmission for targeted malaria control.
  The Journal of infectious diseases 2010 Bousema T, Drakeley C, Gesase S, Hashim R, Magesa S, Mosha F, Otieno S, Carneiro I, Cox J, Msuya E, Kleinschmidt I, Maxwell C, Greenwood B, Riley E, Sauerwein R, Chandramohan D, Gosling R
• Intermittent preventive treatment against malaria: an update.
  Expert review of anti-infective therapy 2010 Gosling RD, Cairns ME, Chico RM, Chandramohan D
• Duration of protection against clinical malaria provided by three regimens of intermittent preventive treatment in Tanzanian infants.
  PloS one 2010 Cairns M, Gosling R, Carneiro I, Gesase S, Mosha JF, Hashim R, Kaur H, Lemnge M, Mosha FW, Greenwood B, Chandramohan D
• Cost implications of improving malaria diagnosis: findings from north-eastern Tanzania.
  PloS one 2010 Mosha JF, Conteh L, Tediosi F, Gesase S, Bruce J, Chandramohan D, Gosling R
• An unusual case of meningococcal meningitis complicated with subdural empyema in a 3 month old infant: a case report.
  Cases journal 2009 Yip K, Gosling RD, Jones V, Hosein IK
• Protective efficacy and safety of three antimalarial regimens for intermittent preventive treatment for malaria in infants: a randomised, double-blind, placebo-controlled trial.
  Lancet (London, England) 2009 Gosling RD, Gesase S, Mosha JF, Carneiro I, Hashim R, Lemnge M, Mosha FW, Greenwood B, Chandramohan D
• Mode of action and choice of antimalarial drugs for intermittent preventive treatment in infants.
  Transactions of the Royal Society of Tropical Medicine and Hygiene 2009 Cairns M, Gosling R, Gesase S, Mosha J, Greenwood B, Chandramohan D
• Community response to intermittent preventive treatment of malaria in infants (IPTi) delivered through the expanded programme of immunization in five African settings.
  Malaria journal 2009 Gysels M, Pell C, Mathanga DP, Adongo P, Odhiambo F, Gosling R, Akweongo P, Mwangi R, Okello G, Mangesho P, Slutsker L, Kremsner PG, Grobusch MP, Hamel MJ, Newman RD, Pool R
• Rapid assessment of malaria transmission using age-specific sero-conversion rates.
  PloS one 2009 Stewart L, Gosling R, Griffin J, Gesase S, Campo J, Hashim R, Masika P, Mosha J, Bousema T, Shekalaghe S, Cook J, Corran P, Ghani A, Riley EM, Drakeley C
• Intermittent preventive treatment of malaria in infants: how does it work and where will it work?
  Tropical medicine & international health : TM & IH 2009 Gosling RD, Carneiro I, Chandramohan D
• RTS,S/AS01E vaccine against malaria.
  The New England journal of medicine 2009 Gosling RD, Chandramohan D
• High resistance of Plasmodium falciparum to sulphadoxine/pyrimethamine in northern Tanzania and the emergence of dhps resistance mutation at Codon 581.
  PloS one 2009 Gesase S, Gosling RD, Hashim R, Ord R, Naidoo I, Madebe R, Mosha JF, Joho A, Mandia V, Mrema H, Mapunda E, Savael Z, Lemnge M, Mosha FW, Greenwood B, Roper C, Chandramohan D
• Placental malaria increases malaria risk in the first 30 months of life: not causal.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2009 Cairns M, Gosling R, Chandramohan D
• Loss of population levels of immunity to malaria as a result of exposure-reducing interventions: consequences for interpretation of disease trends.
  PloS one 2009 Ghani AC, Sutherland CJ, Riley EM, Drakeley CJ, Griffin JT, Gosling RD, Filipe JA
• Overuse of artemisinin-combination therapy in Mto wa Mbu (river of mosquitoes), an area misinterpreted as high endemic for malaria.
  Malaria journal 2008 Mwanziva C, Shekalaghe S, Ndaro A, Mengerink B, Megiroo S, Mosha F, Sauerwein R, Drakeley C, Gosling R, Bousema T
• Tackling malaria today: Beware resurgence of malaria where incidence has fallen.
  BMJ (Clinical research ed.) 2008 Gosling RD, Chandramohan D
• Presumptive treatment of fever cases as malaria: help or hindrance for malaria control?
  Malaria journal 2008 Gosling RD, Drakeley CJ, Mwita A, Chandramohan D
• Asymptomatic malaria associated with protection: not causal.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2008 Gosling RD
• Duration of protection against malaria and anaemia provided by intermittent preventive treatment in infants in Navrongo, Ghana.
  PloS one 2008 Cairns M, Carneiro I, Milligan P, Owusu-Agyei S, Awine T, Gosling R, Greenwood B, Chandramohan D
• Can changes in malaria transmission intensity explain prolonged protection and contribute to high protective efficacy of intermittent preventive treatment for malaria in infants?
  Malaria journal 2008 Gosling RD, Ghani AC, Deen JL, von Seidlein L, Greenwood BM, Chandramohan D
• Effective malaria control: better burden estimates needed.
  Lancet (London, England) 2008 Gosling RD, Drakeley CJ, Chandramohan D
• Implications of attempts to eliminate malaria for front-line clinicians.
  Tropical doctor 2008 Whitty C, Gosling R
• Intermittent preventive therapy for malaria: progress and future directions.
  Current opinion in infectious diseases 2007 Grobusch MP, Egan A, Gosling RD, Newman RD
• Primaquine clears submicroscopic Plasmodium falciparum gametocytes that persist after treatment with sulphadoxine-pyrimethamine and artesunate.
  PloS one 2007 Shekalaghe S, Drakeley C, Gosling R, Ndaro A, van Meegeren M, Enevold A, Alifrangis M, Mosha F, Sauerwein R, Bousema T
• Over-diagnosis of malaria is not a lost cause.
  Malaria journal 2006 Masika PM, Semarundu WJ, Urassa R, Mosha J, Chandramohan D, Gosling RD
• Single-dose sulfadoxine-pyrimethamine in intermittent preventive treatment of malaria.
  The Journal of infectious diseases 2006 Gosling RD, Schellenberg DM, Chandramohan D
• Prevalences of Pneumocystis jiroveci, Mycobacterium tuberculosis and Streptococcus pneumoniae infection in children with severe pneumonia, in a tertiary referral hospital in northern Tanzania.
  Annals of tropical medicine and parasitology 2006 Uriyo J, Gosling RD, Maddox V, Sam NE, Schimana W, Gillespie SH, McHugh TD
• Early bactericidal activity of a moxifloxacin and isoniazid combination in smear-positive pulmonary tuberculosis.
  The Journal of antimicrobial chemotherapy 2005 Gillespie SH, Gosling RD, Uiso L, Sam NE, Kanduma EG, McHugh TD
• Malaria diagnosis and treatment: one size does not fit all.
  PLoS medicine 2005 Drakeley C, Gosling R, Reyburn H
• Mycobacterium tuberculosis lineage: a naming of the parts.
  Tuberculosis (Edinburgh, Scotland) 2005 McHugh TD, Batt SL, Shorten RJ, Gosling RD, Uiso L, Gillespie SH
• Prospective evaluation of BDProbeTec strand displacement amplification (SDA) system for diagnosis of tuberculosis in non-respiratory and respiratory samples.
  Journal of medical microbiology 2004 McHugh TD, Pope CF, Ling CL, Patel S, Billington OJ, Gosling RD, Lipman MC, Gillespie SH
• The bactericidal activity of moxifloxacin in patients with pulmonary tuberculosis.
  American journal of respiratory and critical care medicine 2003 Gosling RD, Uiso LO, Sam NE, Bongard E, Kanduma EG, Nyindo M, Morris RW, Gillespie SH
• A multicentre comparison of a novel surrogate marker for determining the specific potency of anti-tuberculosis drugs.
  The Journal of antimicrobial chemotherapy 2003 Gosling RD, Heifets L, Gillespie SH
• A reiterative method for calculating the early bactericidal activity of antituberculosis drugs.
  American journal of respiratory and critical care medicine 2002 Gillespie SH, Gosling RD, Charalambous BM