Roland Krug, PhD
Associate Professor
Orthopaedic Surgery
School of Medicine

415-353-4945

Roland Krug, PhD, has been at UCSF since 2003. Dr. Krug’s research interests include applying novel Magnetic Resonance Imaging and Spectroscopy tools to advance diagnosis of several musculoskeletal conditions with the ultimate goal to improve the quality of life of patients.

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He has a strong focus on identifying mechanisms that are responsible for low back pain as well as using novel tools such as MR guided high intensity focused ultrasound to treat this condition.

As a principal investigator, Dr. Krug has received substantial support from NIH including two R01, and a UH2/UH3. He is also a director of an U19 grant from the HEAL initiative to fight opioid addiction with a volume of 30 Million USD. Dr. Krug has more than 70 peer-reviewed articles published in the highest ranking journals in the field and serves as a reviewer for more than 15 scientific journals. He reviews grants for NIH as well as the German, Austrian, Dutch, and British National Institutes. He also teaches a class on MR pulse programming in the departmental master program.

Expertise: Musculoskeletal Imaging

Specialty: Advanced pulse sequence development for high field MR imaging, MR spectroscopy and MRgFUS temperature assessment.

Professional Interests: MRI of spine. High-resolution MRI of trabecular and cortical bone, MR fat quantification based on Dixon techniques, image analysis techniques of trabecular bone microstructure. ultra-short-TE (UTE) MRI of cartilage, bone, tendons and ligaments. High-intensity focused ultra-sound (HIFU) applications for bone ablation (temperature mapping of bone using UTE).

Awards

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  • Cover image "Associations between vertebral body fat fraction and intervertebral disc ", Journal of Magnetic Resonance Imaging, 2019
  • Cover Image ""Trabecular Bone Microstructure is Impaired in the Proximal Femur", QUIMS, 2018
  • Cover Image "Variable flip angle three-dimensional fast spin-echo sequence", Journal of Magnetic Resonance Imaging, 2015
  • Editor's Pick: "Bone marrow fat quantification in the presence of trabecular bone", Magnetic Resonance in Medicine, 2014
  • Magna Cum Laude Merit Award, International Society of Magnetic Resonance in Medicine, 2012
  • RSNA Trainee Research Prize for research project, Radiological Society of North America, 2012

Education & Training

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  • Postdoctoral Studies Graduate Division University of California, San Francisco

Interests

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  • ultra-short-echo time (UTE) and high-intensity focused ultra-sound (HIFU)
  • assessment of lower back pain as well as bone health and fracture risk. In particular
  • We use advanced MRI techniques such as MR fat quantification imaging based on Dixon
  • we develop methods to assess spine health (such as spinal endplate
  • disk and marrow changes) as well as bone and marrow quality in the hip

Websites

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Grants and Projects

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Publications (84)

Top publication keywords:
Imaging, Three-DimensionalImage Interpretation, Computer-AssistedBody WaterParaspinal MusclesAdipose TissueMagnetic Resonance ImagingIntervertebral Disc DegenerationBone MarrowLow Back PainImage EnhancementBone and BonesFemurTibiaOsteoporosisLumbar Vertebrae

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