Roger Oria Fernandez, PhD
Specialist
Pharmaceutical Chemistry
School of Pharmacy

Education & Training

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• PhD Biomedicine-Mechanobiology Institute for Bioengineering of Barcelona 2018
• MSc Biomedicine Universitat de Barcelona 2013
• MSc Biomedical Engineering Univeristat de Barcelona 2012
• B.Eng European Engineering Studies Coventry University 2009
• B.Eng Mechanical Engineering Universitat Politecnica de Catalunya 2008

Publications (13)

Top publication keywords:
Extracellular MatrixZonula Occludens-1 ProteinCell MovementCell MembraneLigandsIntegrinsPluripotent Stem CellsPhosphoproteinsPliabilityMechanotransduction, CellularExtracellular SpaceModels, BiologicalFibronectinsFocal AdhesionsAdaptor Proteins, Signal Transducing

• Systematic production of human kidney organoids for transplantation in porcine kidneys during ex vivo machine perfusion.
  Nature biomedical engineering 2025 Garreta E, Moya-Rull D, Centeno A, Marco A, Ullate-Agote A, Amato G, Aranda CJ, Oria R, Lozano-Ojalvo D, Pool MBF, Hamelink TL, Selfa IL, González F, Tarantino C, Montero Salinas A, López San Martín P…
• Axonal injury is a targetable driver of glioblastoma progression.
  Nature 2025 Clements M, Tang W, Florjanic Baronik Z, Simpson Ragdale H, Oria R, Volteras D, White IJ, Beattie G, Uddin I, Lenn T, Lindsay R, Castro Devesa S, Karamched SR, Lythgoe MF, Shahrezaei V, Weaver VM, …
• Differential stiffness between brain vasculature and parenchyma promotes metastatic infiltration through vessel co-option.
  Nature cell biology 2024 Uroz M, Stoddard AE, Sutherland BP, Courbot O, Oria R, Li L, Ravasio CR, Ngo MT, Yang J, Tefft JB, Eyckmans J, Han X, Elosegui-Artola A, Weaver VM, Chen CS
• Cell Migration: Deconstructing the Matrix.
  Current biology : CB 2020 Elosegui-Artola A, Oria R
• Fine tuning the extracellular environment accelerates the derivation of kidney organoids from human pluripotent stem cells.
  Nature materials 2019 Garreta E, Prado P, Tarantino C, Oria R, Fanlo L, Martí E, Zalvidea D, Trepat X, Roca-Cusachs P, Gavaldà-Navarro A, Cozzuto L, Campistol JM, Izpisúa Belmonte JC, Hurtado Del Pozo C, Montserrat N

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• Force loading explains spatial sensing of ligands by cells.
  Nature 2017 Oria R, Wiegand T, Escribano J, Elosegui-Artola A, Uriarte JJ, Moreno-Pulido C, Platzman I, Delcanale P, Albertazzi L, Navajas D, Trepat X, García-Aznar JM, Cavalcanti-Adam EA, Roca-Cusachs P
• Force Triggers YAP Nuclear Entry by Regulating Transport across Nuclear Pores.
  Cell 2017 Elosegui-Artola A, Andreu I, Beedle AEM, Lezamiz A, Uroz M, Kosmalska AJ, Oria R, Kechagia JZ, Rico-Lastres P, Le Roux AL, Shanahan CM, Trepat X, Navajas D, Garcia-Manyes S, Roca-Cusachs P
• Binding of ZO-1 to α5β1 integrins regulates the mechanical properties of α5β1-fibronectin links.
  Molecular biology of the cell 2017 González-Tarragó V, Elosegui-Artola A, Bazellières E, Oria R, Pérez-González C, Roca-Cusachs P
• Myocardial commitment from human pluripotent stem cells: Rapid production of human heart grafts.
  Biomaterials 2016 Garreta E, de Oñate L, Fernández-Santos ME, Oria R, Tarantino C, Climent AM, Marco A, Samitier M, Martínez E, Valls-Margarit M, Matesanz R, Taylor DA, Fernández-Avilés F, Izpisua Belmonte JC, …
• Mechanical regulation of a molecular clutch defines force transmission and transduction in response to matrix rigidity.
  Nature cell biology 2016 Elosegui-Artola A, Oria R, Chen Y, Kosmalska A, Pérez-González C, Castro N, Zhu C, Trepat X, Roca-Cusachs P
• Determination of the static spring constant of electrically-driven quartz tuning forks with two freely oscillating prongs.
  Nanotechnology 2015 González L, Oria R, Botaya L, Puig-Vidal M, Otero J
• Rigidity sensing and adaptation through regulation of integrin types.
  Nature materials 2014 Elosegui-Artola A, Bazellières E, Allen MD, Andreu I, Oria R, Sunyer R, Gomm JJ, Marshall JF, Jones JL, Trepat X, Roca-Cusachs P
• Finite element analysis of electrically excited quartz tuning fork devices.
  Sensors (Basel, Switzerland) 2013 Oria R, Otero J, González L, Botaya L, Carmona M, Puig-Vidal M