Ricardo Barbosa De Almeida, PhD
Full Researcher
Cellular Molecular Pharmacology
School of Medicine

Education & Training

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• PhD Cell and Molecular Biology University of Edinburgh 2008

Websites

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• UCSF Cell Design Institute (celldesigninstitute.org)
• Profile at limlab.ucsf.edu (limlab.ucsf.edu)

Grants and Projects

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• Synthetic epigenetic circuits: tunable cell fate switches controlled by dynamic and combinatorial inputs, NIH, 2021-2026

Publications (8)

Top publication keywords:
Genetic TechniquesProtein KinasesGene EditingCell SizeNucleosomesHeterochromatinPhosphoprotein PhosphatasesRNA InterferenceCRISPR-Cas SystemsSaccharomyces cerevisiaeEndonucleasesSchizosaccharomycesSaccharomyces cerevisiae ProteinsRecombination, GeneticStreptococcus pyogenes

• Nucleosome breathing and remodeling constrain CRISPR-Cas9 function.
  eLife 2016 Isaac RS, Jiang F, Doudna JA, Lim WA, Narlikar GJ, Almeida R
• Expanding the CRISPR imaging toolset with Staphylococcus aureus Cas9 for simultaneous imaging of multiple genomic loci.
  Nucleic acids research 2016 Chen B, Hu J, Almeida R, Liu H, Balakrishnan S, Covill-Cooke C, Lim WA, Huang B
• Engineering complex synthetic transcriptional programs with CRISPR RNA scaffolds.
  Cell 2014 Zalatan JG, Lee ME, Almeida R, Gilbert LA, Whitehead EH, La Russa M, Tsai JC, Weissman JS, Dueber JE, Qi LS, Lim WA
• A global protein kinase and phosphatase interaction network in yeast.
  Science (New York, N.Y.) 2010 Breitkreutz A, Choi H, Sharom JR, Boucher L, Neduva V, Larsen B, Lin ZY, Breitkreutz BJ, Stark C, Liu G, Ahn J, Dewar-Darch D, Reguly T, Tang X, Almeida R, Qin ZS, Pawson T, Gingras AC, Nesvizhskii AI…
• Cell size control: governed by a spatial gradient.
  Developmental cell 2009 Almeida R, Tyers M
• Synthetic heterochromatin bypasses RNAi and centromeric repeats to establish functional centromeres.
  Science (New York, N.Y.) 2009 Kagansky A, Folco HD, Almeida R, Pidoux AL, Boukaba A, Simmer F, Urano T, Hamilton GL, Allshire RC
• Molecular biology: silencing unlimited.
  Current biology : CB 2006 Almeida R, Buscaino A, Allshire RC
• RNA silencing and genome regulation.
  Trends in cell biology 2005 Almeida R, Allshire RC