Reza Abbasi-Asl, PhD
Assistant Professor
Neurology
School of Medicine
We are a research team at the University of California, San Francisco where we investigate the role of advanced computational tools in understanding brain functions and its related disorders.
Show full bio (100 words) Hide full bio
More specifically, our research program revolves around the development of interpretable machine learning tools to (1) integrate multi-modal data collected from the brain (and body) in both microscopic and macroscopic resolutions, (2) predict functions of biological systems in different resolutions, and (3) determine the functional differences across neurological disorders. We are a part of the Neuroscape Center and Cognitive Neuroscience division at UCSF and our team is supported through funding from NIH National Institute of Mental Health, NIH National Institute of Aging, Weill Neurohub, Sandler Program for Breakthrough in Biomedical Research, UCSF Innovation Ventures, and Google.
Awards
Show all (7) Hide
- Catalyst Award, UCSF Innovation Ventures, 2023
- New Frontiers Research Award, Sandler Program for Breakthrough Biomedical Research (PBBR), 2021
- Next Great Ideas Award, Weill Neurohub, 2021
- Eli Jury Award, UC Berkeley, Department of Electrical Engineering and Computer Sciences, 2018
- May J. Koshland Fund in Memory of H.A. Jastro Award, UC Berkeley Graduate Division, 2017
- Excellence Award in Biomedical Engineering, Sharif University of Technology, 2010
- Excellence Award in Electrical Engineering, Amirkabir University of Technology, 2007
Education & Training
Show all (4) Hide
- MSc Electrical Engineering and Computer Sciences UC Berkeley 05/2018
- PhD Electrical Engineering and Computer Sciences UC Berkeley 05/2018
- MSc Biomedical Engineering Sharif University of Technology 01/2013
- BSc Electrical Engineering Amirkabir University of Technology 09/2010
Websites
Show all (2) Hide
- @@reza_abbassi on Twitter (twitter.com)
- Abbasi Lab (abbasilab.org)
Grants and Projects
Show all (8) Hide
- Determining the circuits and signals of sleep dysfunction in Parkinson’s disease through chronic intracranial recordings and closed-loop Deep Brain Stimulation, NIH, 2023-2028
- Integrated functional and structural analysis of an entire column in mouse primary visual cortex, NIH/NIMH, 2022-2025
- Interpretable Machine Learning for Video-Assisted Diagnosis and Tracking of Parkinson’s Disease, UCSF Innovation Ventures, 2023-2025
- Synthetic and Augmented MRI for a shared neuroimaging infrastructure across the Weill Neurohub, Weill Neurohub, 2021-2024
- Neural markers of impending task performance, NIH, 2021-2023
- Revealing Principal Patterns, Brain Areas and Local Gene Regulatory Networks in the Adult Mouse Brain by Interpretable Machine Learning, Weill Neurohub - Next Great Ideas Program, 2021-2023
- Revealing regionalization in whole-organ spatial datasets via interpretable machine learning, Sandler Program for Breakthrough Biomedical Research, 2022-2023
- Revealing neural functions in primary visual cortex via interpretable and biologically realistic neural networks, Sandler Program for Breakthrough Biomedical Research, 2021-2022
Publications (30)
Top publication keywords:
Gene OntologyVisual CortexDeep Brain StimulationMagnetic Resonance ImagingPhotonsModels, NeurologicalVisual PerceptionMotor CortexAtlases as TopicGamma RhythmUnsupervised Machine LearningVision, OcularPhotic StimulationBrainPrincipal Component Analysis
-
Unsupervised pattern identification in spatial gene expression atlas reveals mouse brain regions beyond established ontology.
Proceedings of the National Academy of Sciences of the United States of America 2024 Cahill R, Wang Y, Xian RP, Lee AJ, Zeng H, Yu B, Tasic B, Abbasi-Asl R -
Structurally-constrained encoding framework using a multi-voxel reduced-rank latent model for human natural vision.
Journal of neural engineering 2024 Ranjbar A, Suratgar AA, Menhaj MB, Abbasi-Asl R -
Interpretable video-based tracking and quantification of parkinsonism clinical motor states.
NPJ Parkinson's disease 2024 Deng D, Ostrem JL, Nguyen V, Cummins DD, Sun J, Pathak A, Little S, Abbasi-Asl R -
Data-driven fine-grained region discovery in the mouse brain with transformers.
bioRxiv : the preprint server for biology 2024 Lee AJ, Yao S, Lusk N, Ng L, Kunst M, Zeng H, Tasic B, Abbasi-Asl R -
Motor network gamma oscillations in chronic home recordings predict dyskinesia in Parkinson's disease.
Brain : a journal of neurology 2024 Olaru M, Cernera S, Hahn A, Wozny TA, Anso J, de Hemptinne C, Little S, Neumann WJ, Abbasi-Asl R, Starr PA
Show all (25 more) Hide
-
Interpretable Video-Based Tracking and Quantification of Parkinsonism Clinical Motor States
medRxiv preprint 2023 D. Deng, J. L. Ostrem, V. Nguyen, D. D. Cummins, J. Sun, A. Pathak, S. Little*, R. Abbasi-Asl* -
Interpretable prototype discovery in deep learning based time series classification
Integrated Systems: Innovations and Applications, Springer book chapter 2023 Gaurav Ghosal, R. Abbasi-Asl -
Journal of Vision
Reconstructing visual experience from a large-scale biologically realistic model of mouse primary visual cortex 2023 R. Abbasi-Asl, Y. Chi, H. Yang, K. Dai, A. Arkhipov -
Neurology
Diurnal Step Count Patterns in Progressive Multiple Sclerosis 2023 D. Navani, V. Block, B. Cree, R. Abbasi-Asl -
The entropic heart: Tracking the psychedelic state via heart rate dynamics
bioRxiv preprint 2023 F. E. Rosas, P. A. M. Mediano, C. Timmermann, A. I Luppi, D. Candia-Rivera, R. Abbasi-Asl, A. Gazzaley, M. L. Kringelbach, S. D. Muthukumaraswamy, D. Bor, S. Garfinkel, R. Carhart-Harris -
Unsupervised pattern discovery in spatial gene expression atlas reveals mouse brain regions beyond established ontology
bioRxiv preprint 2023 R. Cahill*, Y. Wang*, Patrick Xian, A. Lee, H. Zeng, B. Yu, B. Tasic, R. Abbasi-Asl -
Machine Learning for Uncovering Biological Insights in Spatial Transcriptomics Data.
ArXiv 2023 Lee AJ, Cahill R, Abbasi-Asl R -
Editorial: Functional microcircuits in the brain and in artificial intelligent systems.
Frontiers in computational neuroscience 2023 Lee JH, Choe Y, Ardid S, Abbasi-Asl R, McCarthy M, Hu B -
Compression-enabled interpretability of voxel-wise encoding models
bioRxiv preprint 2022 F Kamali, AA Suratgar, M Menhaj, R Abbasi-Asl -
Robust Registration of Medical Images in the Presence of Spatially-Varying Noise
Algorithms 2022 Reza Abbasi-Asl, Aboozar Ghaffari, Emad Fatemizadeh -
Journal of Vision
A large-scale standardized survey of neural receptive fields in an entire column in mouse V1 2021 R. Abbasi-Asl, A. Muslim, J. Larkin, K. Takasaki, D. Millman, D. Denman, J. Lecoq, A, Arkhipov, N. W Gouwens, J. Waters, R C. Reid, S. EJ de Vries -
Multi-Modal Prototype Learning for Interpretable Multivariable Time Series Classification
arxiv 2021 Gaurav R Ghosal, Reza Abbasi-Asl -
Structural Compression of Convolutional Neural Networks with Applications in Interpretability.
Frontiers in big data 2021 Abbasi-Asl R, Yu B -
Systematic Integration of Structural and Functional Data into Multi-scale Models of Mouse Primary Visual Cortex.
Neuron 2020 Billeh YN, Cai B, Gratiy SL, Dai K, Iyer R, Gouwens NW, Abbasi-Asl R, Jia X, Siegle JH, Olsen SR, Koch C, Mihalas S, Arkhipov A -
Superficial Bound of the Depth Limit of Two-Photon Imaging in Mouse Brain.
eNeuro 2020 Takasaki K, Abbasi-Asl R, Waters J -
Definitions, methods, and applications in interpretable machine learning.
Proceedings of the National Academy of Sciences of the United States of America 2019 Murdoch WJ, Singh C, Kumbier K, Abbasi-Asl R, Yu B -
3-Photon Calcium Imaging of Deep Cortical Layers for Functional Connectomics
Optics and the Brain 2019 Kevin Takasaki, Josh Larkin, Reza Abbasi-Asl, Dan Denman, Dan Millman, Saskia de Vries, Marc Takeno, Nuno M da Costa, R Clay Reid, Jack Waters -
Brain-Computer Interface in Virtual Reality
9th International IEEE EMBS Conference on Neural Engineering (NER) 2019 R. Abbasi-Asl, M. Keshavarzi, D. Y. Chan -
Visual physiology of the layer 4 cortical circuit in silico.
PLoS computational biology 2018 Arkhipov A, Gouwens NW, Billeh YN, Gratiy S, Iyer R, Wei Z, Xu Z, Abbasi-Asl R, Berg J, Buice M, Cain N, da Costa N, de Vries S, Denman D, Durand S, Feng D, Jarsky T, Lecoq J, Lee B, Li L, Mihalas S, … -
The DeepTune framework for modeling and characterizing neurons in visual cortex area V4
bioArxiv 2018 Reza Abbasi-Asl, Yuansi Chen, Adam Bloniarz, Michael Oliver, Ben DB Willmore, Jack L Gallant, Bin Yu -
Interpreting Convolutional Neural Networks Through Compression
NIPS 2017 Symposium on Interpretable Machine Learning 2017 Reza Abbasi-Asl, Bin Yu -
Do retinal ganglion cells project natural scenes to their principal subspace and whiten them?
IEEE Proceedings of 50th Asilomar Conference on Signals, Systems and Computers 2016 R. Abbasi-Asl, C. Pehlevan, B. Yu and D. B. Chklovskii -
Automatic b-spline image registration using histogram-based landmark extraction
IEEE-EMBS Conference on Biomedical Engineering and Sciences 2012 Abdollah Ghanbari, Reza Abbasi-Asl, Aboozar Ghaffari, Emad Fatemizadeh -
Estimation of muscle force with emg signals using hammerstein-wiener model
5th Kuala Lumpur International Conference on Biomedical Engineering 2011 Reza Abbasi-Asl, Rahman Khorsandi, Shahrokh Farzampour, Edmond Zahedi -
Hammerstein-Wiener model: A new approach to the estimation of formal neural information
Basic and Clinical Neuroscience Reza Abbasi-Asl, Rahman Khorsandi, Bijan Vosooghi-Vahdat