Renaud La Joie, PhD
Assistant Professor
Neurology
School of Medicine
Awards
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- Christopher Clark award, Human Amyloid Imaging conference, 2024
- de Leon Prize in Neuroimaging, Alzheimer's Association, International Society to Advance Alzheimer's Research and Treatment, 2020
- Dean’s Awards for Excellence in Mentoring, UCSF, 2020
- research education component scholarship, UCSF Alzheimer's Disease Research Center, 2019
- Young Investigator Award, Human Amyloid Imaging, 2018
- Young Scientist Award, Alzheimer's Association, 2017
- Post-doc poster competition winner, Alzheimer's Association International Conference, 2017
- Best datablitz/poster presentation, Alzheimer's Imaging Consortium, 2017
- Best Poster, Réunion Francophone sur la Maladie d'Alzheimer & les syndromes apparentés, 2016
Education & Training
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- post doc Clinical Neuroscience University of California, San Francisco 2020
- post doc Neuroscience University of California, Berkeley 2014
- PhD Psychology Université de Caen Basse-Normandie 2013
- MSc Neuroscience Université Pierre et Marie Curie (Paris 6) 2009
- BS Medicine (premed) Université de Caen Basse-Normandie 2008
Interests
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- cognition
- aging
- biomarker
- positron emission tomography
- neuroimaging
- Frontotemporal Lobar Degeneration
- tau
- Frontotemporal dementia
- Alzheimer's disease
- beta-amyloid
- dementia
Websites
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- Google Scholar page (scholar.google.com)
- Name Drop (how to pronounce my name!) (namedrop.io)
- Global Brain Health Institute (gbhi.org)
- Rabinovici Lab (rabinovicilab.ucsf.edu)
Grants and Projects
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- Connectome-based spread of neurodegenerative processes in Alzheimer?s disease, NIH, 2020-2022
- Multimodal imaging of neurodegeneration processes and their propagation, Alzheimer's Association, 2016-2019
Publications (160)
Top publication keywords:
Aphasia, Primary ProgressivePositron-Emission TomographyApolipoprotein E4Cognitive DysfunctionAlzheimer DiseaseCarbolinesSupranuclear Palsy, ProgressiveFrontotemporal Lobar DegenerationNeurodegenerative DiseasesAmyloid beta-PeptidesHippocampustau ProteinsAtrophyAniline CompoundsFrontotemporal Dementia
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Plasma phosphorylated tau 217 and phosphorylated tau 181 as biomarkers in Alzheimer's disease and frontotemporal lobar degeneration: a retrospective diagnostic performance study.
The Lancet. Neurology 2021 Thijssen EH, La Joie R, Strom A, Fonseca C, Iaccarino L, Wolf A, Spina S, Allen IE, Cobigo Y, Heuer H, VandeVrede L, Proctor NK, Lago AL, Baker S, Sivasankaran R, Kieloch A, Kinhikar A, Yu L, Valentin… -
Association of APOE4 and Clinical Variability in Alzheimer Disease With the Pattern of Tau- and Amyloid-PET.
Neurology 2020 La Joie R, Visani AV, Lesman-Segev OH, Baker SL, Edwards L, Iaccarino L, Soleimani-Meigooni DN, Mellinger T, Janabi M, Miller ZA, Perry DC, Pham J, Strom A, Gorno-Tempini ML, Rosen HJ, Miller BL, … -
Prospective longitudinal atrophy in Alzheimer's disease correlates with the intensity and topography of baseline tau-PET.
Science translational medicine 2020 La Joie R, Visani AV, Baker SL, Brown JA, Bourakova V, Cha J, Chaudhary K, Edwards L, Iaccarino L, Janabi M, Lesman-Segev OH, Miller ZA, Perry DC, O'Neil JP, Pham J, Rojas JC, Rosen HJ, Seeley WW, … -
Neuropsychiatric profiles and cerebral amyloid burden in adults without dementia.
Dementia and geriatric cognitive disorders 2024 Gontrum EQ, Paolillo EW, Lee S, Diaz V, Ehrenberg A, Saloner R, Mundada NS, La Joie R, Rabinovici G, Kramer JH, Casaletto K -
Linking Type and Extent of Head Trauma to Cavum Septum Pellucidum in Older Adults With and Without Alzheimer Disease and Related Dementias.
Neurology 2024 Asken BM, Tanner JA, Vandevrede L, Apple A, Chapleau M, Gaynor LS, Lane-Donovan C, Lenio S, Yadollahikhales G, Lee S, Gontrum E, Knudtson M, Iaccarino L, La Joie R, Cobigo Y, Staffaroni AM, Casaletto …
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Biomarker-based staging of Alzheimer disease: rationale and clinical applications.
Nature reviews. Neurology 2024 Therriault J, Schindler SE, Salvadó G, Pascoal TA, Benedet AL, Ashton NJ, Karikari TK, Apostolova L, Murray ME, Verberk I, Vogel JW, La Joie R, Gauthier S, Teunissen C, Rabinovici GD, Zetterberg H, … -
Comparison of approaches to control for intracranial volume in research on the association of brain volumes with cognitive outcomes.
Human brain mapping 2024 Wang J, Hill-Jarrett T, Buto P, Pederson A, Sims KD, Zimmerman SC, DeVost MA, Ferguson E, Lacar B, Yang Y, Choi M, Caunca MR, La Joie R, Chen R, Glymour MM, Ackley SF -
Comparison of histological delineations of medial temporal lobe cortices by four independent neuroanatomy laboratories.
Hippocampus 2024 Wuestefeld A, Baumeister H, Adams JN, de Flores R, Hodgetts CJ, Mazloum-Farzaghi N, Olsen RK, Puliyadi V, Tran TT, Bakker A, Canada KL, Dalton MA, Daugherty AM, La Joie R, Wang L, Bedard ML, Buendia E… -
Highly accurate blood test for Alzheimer's disease is similar or superior to clinical cerebrospinal fluid tests.
Nature medicine 2024 Barthélemy NR, Salvadó G, Schindler SE, He Y, Janelidze S, Collij LE, Saef B, Henson RL, Chen CD, Gordon BA, Li Y, La Joie R, Benzinger TLS, Morris JC, Mattsson-Carlgren N, Palmqvist S, Ossenkoppele R… -
Considerations for Use of Blood-Based Biomarkers in Epidemiologic Dementia Research.
American journal of epidemiology 2024 Hayes-Larson E, Ackley SF, Turney IC, La Joie R, Mayeda ER, Glymour MM, for the Alzheimer's Disease Neuroimaging Initiative -
Demographic, clinical, biomarker, and neuropathological correlates of posterior cortical atrophy: an international cohort study and individual participant data meta-analysis.
The Lancet. Neurology 2024 Chapleau M, La Joie R, Yong K, Agosta F, Allen IE, Apostolova L, Best J, Boon BDC, Crutch S, Filippi M, Fumagalli GG, Galimberti D, Graff-Radford J, Grinberg LT, Irwin DJ, Josephs KA, Mendez MF, … -
Spatiotemporal characteristics of neurophysiological changes in patients with four-repeat tauopathies.
Annals of clinical and translational neurology 2024 Samudra N, Lerner H, Yack L, Walsh CM, Kirsch HE, Kudo K, Yballa C, La Joie R, Gorno-Tempini ML, Spina S, Seeley WW, Neylan TC, Miller BL, Rabinovici GD, Boxer A, Grinberg LT, Rankin KP, Nagarajan SS,… -
Scalable plasma and digital cognitive markers for diagnosis and prognosis of Alzheimer's disease and related dementias.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2024 Tsoy E, La Joie R, VandeVrede L, Rojas JC, Yballa C, Chan B, Lago AL, Rodriguez AM, Goode CA, Erlhoff SJ, Tee BL, Windon C, Lanata S, Kramer JH, Miller BL, Dilworth-Anderson P, Boxer AL, Rabinovici GD… -
Genetic risk score for Alzheimer's disease predicts brain volume differences in mid and late life in UK biobank participants.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2024 Buto PT, Wang J, La Joie R, Zimmerman SC, Glymour MM, Ackley SF, Hoffmann TJ, Yaffe K, Zeki Al Hazzouri A, Brenowitz WD -
Novel avenues of tau research.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2024 Sexton CE, Bitan G, Bowles KR, Brys M, Buée L, Maina MB, Clelland CD, Cohen AD, Crary JF, Dage JL, Diaz K, Frost B, Gan L, Goate AM, Golbe LI, Hansson O, Karch CM, Kolb HC, La Joie R, Lee SE, … -
A (Sub)field Guide to Quality Control in Hippocampal Subfield Segmentation on Highresolution T2-weighted MRI.
bioRxiv : the preprint server for biology 2023 Canada KL, Mazloum-Farzaghi N, Rådman G, Adams JN, Bakker A, Baumeister H, Berron D, Bocchetta M, Carr V, Dalton MA, de Flores R, Keresztes A, La Joie R, Mueller SG, Raz N, Santini T, Shaw T, Stark … -
[18F]PI-2620 Binding Patterns in Patients with Suspected Alzheimer Disease and Frontotemporal Lobar Degeneration.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2023 Blazhenets G, Soleimani-Meigooni DN, Thomas W, Mundada N, Brendel M, Vento S, VandeVrede L, Heuer HW, Ljubenkov P, Rojas JC, Chen MK, Amuiri AN, Miller Z, Gorno-Tempini ML, Miller BL, Rosen HJ, Litvan… -
Longitudinal clinical, cognitive and biomarker profiles in dominantly inherited versus sporadic early-onset Alzheimer's disease.
Brain communications 2023 Llibre-Guerra JJ, Iaccarino L, Coble D, Edwards L, Li Y, McDade E, Strom A, Gordon B, Mundada N, Schindler SE, Tsoy E, Ma Y, Lu R, Fagan AM, Benzinger TLS, Soleimani-Meigooni D, Aschenbrenner AJ, … -
Head-to-head comparison between plasma p-tau217 and flortaucipir-PET in amyloid-positive patients with cognitive impairment.
Alzheimer's research & therapy 2023 Mundada NS, Rojas JC, Vandevrede L, Thijssen EH, Iaccarino L, Okoye OC, Shankar R, Soleimani-Meigooni DN, Lago AL, Miller BL, Teunissen CE, Heuer H, Rosen HJ, Dage JL, Jagust WJ, Rabinovici GD, Boxer … -
Co-pathology may impact outcomes of amyloid-targeting treatments: clinicopathological results from two patients treated with aducanumab.
Acta neuropathologica 2023 VandeVrede L, La Joie R, Horiki S, Mundada NS, Koestler M, Hwang JH, Ljubenkov PA, Rojas JC, Rabinovici GD, Boxer AL, Seeley WW -
Amyloid and tau-PET in early-onset AD: Baseline data from the Longitudinal Early-onset Alzheimer's Disease Study (LEADS).
Alzheimer's & dementia : the journal of the Alzheimer's Association 2023 Cho H, Mundada NS, Apostolova LG, Carrillo MC, Shankar R, Amuiri AN, Zeltzer E, Windon CC, Soleimani-Meigooni DN, Tanner JA, Heath CL, Lesman-Segev OH, Aisen P, Eloyan A, Lee HS, Hammers DB, Kirby K, … -
Determinants of cognitive and brain resilience to tau pathology: a longitudinal analysis.
Brain : a journal of neurology 2023 Bocancea DI, Svenningsson AL, van Loenhoud AC, Groot C, Barkhof F, Strandberg O, Smith R, Alzheimer’s Disease Neuroimaging Initiative, La Joie R, Rosen HJ, Pontecorvo MJ, Rabinovici GD, van der Flier … -
Influence of amyloid and diagnostic syndrome on non-traditional memory scores in early-onset Alzheimer's disease.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2023 Bushnell J, Hammers DB, Aisen P, Dage JL, Eloyan A, Foroud T, Grinberg LT, Iaccarino L, Jack CR, Kirby K, Kramer J, Koeppe R, Kukull WA, La Joie R, Mundada NS, Murray ME, Nudelman K, Rumbaugh M, … -
Amyloid-Targeting Monoclonal Antibodies for Alzheimer Disease.
JAMA 2023 Rabinovici GD, La Joie R -
Sex and APOE ε4 carrier effects on atrophy, amyloid PET, and tau PET burden in early-onset Alzheimer's disease.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2023 Nemes S, Logan PE, Manchella MK, Mundada NS, La Joie R, Polsinelli AJ, Hammers DB, Koeppe RA, Foroud TM, Nudelman KN, Eloyan A, Iaccarino L, Dorsant-Ardón V, Taurone A, Thangarajah M, Dage JL, Aisen P… -
Cerebrospinal fluid biomarkers in the Longitudinal Early-onset Alzheimer's Disease Study.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2023 Dage JL, Eloyan A, Thangarajah M, Hammers DB, Fagan AM, Gray JD, Schindler SE, Snoddy C, Nudelman KNH, Faber KM, Foroud T, Aisen P, Griffin P, Grinberg LT, Iaccarino L, Kirby K, Kramer J, Koeppe R, … -
White matter hyperintensities are higher among early-onset Alzheimer's disease participants than their cognitively normal and early-onset nonAD peers: Longitudinal Early-onset Alzheimer's Disease Study (LEADS).
Alzheimer's & dementia : the journal of the Alzheimer's Association 2023 Eloyan A, Thangarajah M, An N, Borowski BJ, Reddy AL, Aisen P, Dage JL, Foroud T, Ghetti B, Griffin P, Hammers D, Iaccarino L, Jack CR, Kirby K, Kramer J, Koeppe R, Kukull WA, La Joie R, Mundada NS, … -
Alzheimer's pathology is associated with altered cognition, brain volume, and plasma biomarker patterns in traumatic encephalopathy syndrome.
Alzheimer's research & therapy 2023 Asken BM, Tanner JA, Gaynor LS, VandeVrede L, Mantyh WG, Casaletto KB, Staffaroni AM, Fonseca C, Shankar R, Grant H, Smith K, Lago AL, Xu H, La Joie R, Cobigo Y, Rosen H, Perry DC, Rojas JC, Miller BL… -
Psychological stress is associated with arterial inflammation in people living with treated HIV infection.
Brain, behavior, and immunity 2023 Chow FC, Mundada NS, Abohashem S, La Joie R, Iaccarino L, Arechiga VM, Swaminathan S, Rabinovici GD, Epel ES, Tawakol A, Hsue PY -
Network anatomy in logopenic variant of primary progressive aphasia.
Human brain mapping 2023 Mandelli ML, Lorca-Puls DL, Lukic S, Montembeault M, Gajardo-Vidal A, Licata A, Scheffler A, Battistella G, Grasso SM, Bogley R, Ratnasiri BM, La Joie R, Mundada NS, Europa E, Rabinovici G, Miller BL,… -
Baseline neuropsychiatric symptoms and psychotropic medication use midway through data collection of the Longitudinal Early-Onset Alzheimer's Disease Study (LEADS) cohort.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2023 Polsinelli AJ, Wonderlin RJ, Hammers DB, Garcia AP, Eloyan A, Taurone A, Thangarajah M, Beckett L, Gao S, Wang S, Kirby K, Logan PE, Aisen P, Dage JL, Foroud T, Griffin P, Iaccarino L, Kramer JH, … -
Profiling baseline performance on the Longitudinal Early-Onset Alzheimer's Disease Study (LEADS) cohort near the midpoint of data collection.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2023 Hammers DB, Eloyan A, Taurone A, Thangarajah M, Beckett L, Gao S, Kirby K, Aisen P, Dage JL, Foroud T, Griffin P, Grinberg LT, Jack CR, Kramer J, Koeppe R, Kukull WA, Mundada NS, La Joie R, Soleimani-… -
Network anatomy in logopenic variant of primary progressive aphasia.
medRxiv : the preprint server for health sciences 2023 Mandelli ML, Lorca-Puls DL, Lukic S, Montembeault M, Gajardo-Vidal A, Licata A, Scheffler A, Battistella G, Grasso SM, Bogley R, Ratnasiri BM, La Joie R, Mundada NS, Europa E, Rabinovici G, Miller BL,… -
Evaluation of Plasma Phosphorylated Tau217 for Differentiation Between Alzheimer Disease and Frontotemporal Lobar Degeneration Subtypes Among Patients With Corticobasal Syndrome.
JAMA neurology 2023 VandeVrede L, La Joie R, Thijssen EH, Asken BM, Vento SA, Tsuei T, Baker SL, Cobigo Y, Fonseca C, Heuer HW, Kramer JH, Ljubenkov PA, Rabinovici GD, Rojas JC, Rosen HJ, Staffaroni AM, Boeve BF, … -
Association of the Informant-Reported Memory Decline With Cognitive and Brain Deterioration Through the Alzheimer Clinical Continuum.
Neurology 2023 Kuhn E, Perrotin A, La Joie R, Touron E, Dautricourt S, Vanhoutte M, Vivien D, de La Sayette V, Chételat G, Alzheimer's Disease Neuroimaging Initiative -
Prevalence, Timing, and Network Localization of Emergent Visual Creativity in Frontotemporal Dementia.
JAMA neurology 2023 Friedberg A, Pasquini L, Diggs R, Glaubitz EA, Lopez L, Illán-Gala I, Iaccarino L, La Joie R, Mundada N, Knudtson M, Neylan K, Brown J, Allen IE, Rankin KP, Bonham LW, Yokoyama JS, Ramos EM, Geschwind… -
Robustness of CSF Aβ42/40 and Aβ42/P-tau181 measured using fully automated immunoassays to detect AD-related outcomes.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2023 Leuzy A, Mattsson-Carlgren N, Cullen NC, Stomrud E, Palmqvist S, La Joie R, Iaccarino L, Zetterberg H, Rabinovici G, Blennow K, Janelidze S, Hansson O -
Medial Temporal Lobe Tau Aggregation Relates to Divergent Cognitive and Emotional Empathy Abilities in Alzheimer's Disease.
Journal of Alzheimer's disease : JAD 2023 Chow TE, Veziris CR, Mundada N, Martinez-Arroyo AI, Kramer JH, Miller BL, Rosen HJ, Gorno-Tempini ML, Rankin KP, Seeley WW, Rabinovici GD, La Joie R, Sturm VE -
Amyloid, tau and metabolic PET correlates of cognition in early and late-onset Alzheimer's disease.
Brain : a journal of neurology 2022 Tanner JA, Iaccarino L, Edwards L, Asken BM, Gorno-Tempini ML, Kramer JH, Pham J, Perry DC, Possin K, Malpetti M, Mellinger T, Miller BL, Miller Z, Mundada NS, Rosen HJ, Soleimani-Meigooni DN, Strom A… -
AD and non-AD mediators of the pathway between the APOE genotype and cognition.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2022 Nichols E, Brickman AM, Casaletto KB, Dams-O'Connor K, George KM, Kumar RG, Palta P, Rabin JS, Satizabal CL, Schneider J, Pa J, La Joie R -
Increasing empathic concern relates to salience network hyperconnectivity in cognitively healthy older adults with elevated amyloid-β burden.
NeuroImage. Clinical 2022 Chow TE, Veziris CR, La Joie R, Lee AJ, Brown JA, Yokoyama JS, Rankin KP, Kramer JH, Miller BL, Rabinovici GD, Seeley WW, Sturm VE -
Sex-specific effects of microglial activation on Alzheimer's disease proteinopathy in older adults.
Brain : a journal of neurology 2022 Casaletto KB, Nichols E, Aslanyan V, Simone SM, Rabin JS, La Joie R, Brickman AM, Dams-O'Connor K, Palta P, Kumar RG, George KM, Satizabal CL, Schneider J, Pa J -
Cerebral amyloid angiopathy interacts with neuritic amyloid plaques to promote tau and cognitive decline.
Brain : a journal of neurology 2022 Rabin JS, Nichols E, La Joie R, Casaletto KB, Palta P, Dams-O'Connor K, Kumar RG, George KM, Satizabal CL, Schneider JA, Pa J, Brickman AM -
Multi-feature computational framework for combined signatures of dementia in underrepresented settings.
Journal of neural engineering 2022 Moguilner S, Birba A, Fittipaldi S, Gonzalez-Campo C, Tagliazucchi E, Reyes P, Matallana D, Parra MA, Slachevsky A, Farías G, Cruzat J, García A, Eyre HA, La Joie R, Rabinovici G, Whelan R, Ibáñez A -
Multi-Modal Biomarkers of Repetitive Head Impacts and Traumatic Encephalopathy Syndrome: A Clinicopathological Case Series.
Journal of neurotrauma 2022 Asken BM, Tanner JA, VandeVrede L, Casaletto KB, Staffaroni AM, Mundada N, Fonseca C, Iaccarino L, La Joie R, Tsuei T, Mladinov M, Grant H, Shankar R, Wang KKW, Xu H, Cobigo Y, Rosen H, Gardner RC, … -
Imaging Alzheimer's pathology stage by stage.
Nature aging 2022 Malpetti M, La Joie R -
Tau Beats Amyloid in Predicting Brain Atrophy in Alzheimer Disease: Implications for Prognosis and Clinical Trials.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2022 Malpetti M, Joie R, Rabinovici GD -
Altered excitatory and inhibitory neuronal subpopulation parameters are distinctly associated with tau and amyloid in Alzheimer's disease.
eLife 2022 Ranasinghe KG, Verma P, Cai C, Xie X, Kudo K, Gao X, Lerner H, Mizuiri D, Strom A, Iaccarino L, La Joie R, Miller BL, Gorno-Tempini ML, Rankin KP, Jagust WJ, Vossel K, Rabinovici GD, Raj A, Nagarajan … -
Plasma P-tau181 and P-tau217 in Patients With Traumatic Encephalopathy Syndrome With and Without Evidence of Alzheimer Disease Pathology.
Neurology 2022 Asken BM, Tanner JA, VandeVrede L, Mantyh WG, Casaletto KB, Staffaroni AM, La Joie R, Iaccarino L, Soleimani-Meigooni D, Rojas JC, Gardner RC, Miller BL, Grinberg LT, Boxer AL, Kramer JH, Rabinovici … -
Regional Aβ-tau interactions promote onset and acceleration of Alzheimer's disease tau spreading.
Neuron 2022 Lee WJ, Brown JA, Kim HR, La Joie R, Cho H, Lyoo CH, Rabinovici GD, Seong JK, Seeley WW, Alzheimer’s Disease Neuroimaging Initiative -
Cortical hypometabolism reflects local atrophy and tau pathology in symptomatic Alzheimer's disease.
Brain : a journal of neurology 2022 Strom A, Iaccarino L, Edwards L, Lesman-Segev OH, Soleimani-Meigooni DN, Pham J, Baker SL, Landau SM, Jagust WJ, Miller BL, Rosen HJ, Gorno-Tempini ML, Rabinovici GD, La Joie R, Alzheimer’s Disease … -
Quantification of amyloid beta and tau PET without a structural MRI.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2022 Landau SM, Ward TJ, Murphy A, Iaccarino L, Harrison TM, La Joie R, Baker S, Koeppe RA, Jagust WJ, Alzheimer's Disease Neuroimaging Initiative -
Dissecting the clinical heterogeneity of early-onset Alzheimer's disease.
Molecular psychiatry 2022 Sirkis DW, Bonham LW, Johnson TP, La Joie R, Yokoyama JS -
Diagnostic Accuracy of Magnetic Resonance Imaging Measures of Brain Atrophy Across the Spectrum of Progressive Supranuclear Palsy and Corticobasal Degeneration.
JAMA network open 2022 Illán-Gala I, Nigro S, VandeVrede L, Falgàs N, Heuer HW, Painous C, Compta Y, Martí MJ, Montal V, Pagonabarraga J, Kulisevsky J, Lleó A, Fortea J, Logroscino G, Quattrone A, Quattrone A, Perry DC, … -
Cerebrospinal Fluid Biomarkers in Autopsy-Confirmed Alzheimer Disease and Frontotemporal Lobar Degeneration.
Neurology 2022 Mattsson-Carlgren N, Grinberg LT, Boxer A, Ossenkoppele R, Jonsson M, Seeley W, Ehrenberg A, Spina S, Janelidze S, Rojas-Martinex J, Rosen H, La Joie R, Lesman-Segev O, Iaccarino L, Kollmorgen G, … -
rPOP: Robust PET-only processing of community acquired heterogeneous amyloid-PET data.
NeuroImage 2021 Iaccarino L, La Joie R, Koeppe R, Siegel BA, Hillner BE, Gatsonis C, Whitmer RA, Carrillo MC, Apgar C, Camacho MR, Nosheny R, Rabinovici GD, Alzheimer's Disease Neuroimaging Initiative -
The many dimensions of human hippocampal organization and (dys)function.
Trends in neurosciences 2021 Genon S, Bernhardt BC, La Joie R, Amunts K, Eickhoff SB -
Fusiform Gyrus Phospho-Tau is Associated with Failure of Proper Name Retrieval in Aging.
Annals of neurology 2021 Tennant VR, Harrison TM, Adams JN, La Joie R, Winer JR, Jagust WJ -
Social Behavior Observer Checklist: Patterns of Spontaneous Behaviors Differentiate Patients With Neurodegenerative Disease From Healthy Older Adults.
Frontiers in neurology 2021 Rankin KP, Toller G, Gavron L, La Joie R, Wu T, Shany-Ur T, Callahan P, Krassner M, Kramer JH, Miller BL -
Effect of the Histone Deacetylase Inhibitor FRM-0334 on Progranulin Levels in Patients With Progranulin Gene Haploinsufficiency: A Randomized Clinical Trial.
JAMA network open 2021 Ljubenkov PA, Edwards L, Iaccarino L, La Joie R, Rojas JC, Koestler M, Harris B, Boeve BF, Borroni B, van Swieten JC, Grossman M, Pasquier F, Frisoni GB, Mummery CJ, Vandenberghe R, Le Ber I, … -
Comorbid neuropathological diagnoses in early versus late-onset Alzheimer's disease.
Brain : a journal of neurology 2021 Spina S, La Joie R, Petersen C, Nolan AL, Cuevas D, Cosme C, Hepker M, Hwang JH, Miller ZA, Huang EJ, Karydas AM, Grant H, Boxer AL, Gorno-Tempini ML, Rosen HJ, Kramer JH, Miller BL, Seeley WW, … -
Neuroimaging in Frontotemporal Dementia: Heterogeneity and Relationships with Underlying Neuropathology.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2021 Peet BT, Spina S, Mundada N, La Joie R -
Accuracy of Tau Positron Emission Tomography as a Prognostic Marker in Preclinical and Prodromal Alzheimer Disease: A Head-to-Head Comparison Against Amyloid Positron Emission Tomography and Magnetic Resonance Imaging.
JAMA neurology 2021 Ossenkoppele R, Smith R, Mattsson-Carlgren N, Groot C, Leuzy A, Strandberg O, Palmqvist S, Olsson T, Jögi J, Stormrud E, Cho H, Ryu YH, Choi JY, Boxer AL, Gorno-Tempini ML, Miller BL, Soleimani-… -
A multicenter comparison of [18F]flortaucipir, [18F]RO948, and [18F]MK6240 tau PET tracers to detect a common target ROI for differential diagnosis.
European journal of nuclear medicine and molecular imaging 2021 Leuzy A, Pascoal TA, Strandberg O, Insel P, Smith R, Mattsson-Carlgren N, Benedet AL, Cho H, Lyoo CH, La Joie R, Rabinovici GD, Ossenkoppele R, Rosa-Neto P, Hansson O -
Retinal imaging demonstrates reduced capillary density in clinically unimpaired APOE ε4 gene carriers.
Alzheimer's & dementia (Amsterdam, Netherlands) 2021 Elahi FM, Ashimatey SB, Bennett DJ, Walters SM, La Joie R, Jiang X, Wolf A, Cobigo Y, Staffaroni AM, Rosen HJ, Miller BL, Rabinovici GD, Kramer JH, Green AJ, Kashani AH -
Four distinct trajectories of tau deposition identified in Alzheimer's disease.
Nature medicine 2021 Vogel JW, Young AL, Oxtoby NP, Smith R, Ossenkoppele R, Strandberg OT, La Joie R, Aksman LM, Grothe MJ, Iturria-Medina Y, Alzheimer’s Disease Neuroimaging Initiative, Pontecorvo MJ, Devous MD, … -
Multimodal neuroimaging of sex differences in cognitively impaired patients on the Alzheimer's continuum: greater tau-PET retention in females.
Neurobiology of aging 2021 Edwards L, La Joie R, Iaccarino L, Strom A, Baker SL, Casaletto KB, Cobigo Y, Grant H, Kim M, Kramer JH, Mellinger TJ, Pham J, Possin KL, Rosen HJ, Soleimani-Meigooni DN, Wolf A, Miller BL, Rabinovici… -
Heterogeneous distribution of tau pathology in the behavioural variant of Alzheimer's disease.
Journal of neurology, neurosurgery, and psychiatry 2021 Singleton E, Hansson O, Pijnenburg YAL, La Joie R, Mantyh WG, Tideman P, Stomrud E, Leuzy A, Johansson M, Strandberg O, Smith R, Berendrecht E, Miller BL, Iaccarino L, Edwards L, Strom A, Wolters EE, … -
The Rapid Naming Test: Development and initial validation in typically aging adults.
The Clinical neuropsychologist 2021 Stiver J, Staffaroni AM, Walters SM, You MY, Casaletto KB, Erlhoff SJ, Possin KL, Lukic S, La Joie R, Rabinovici GD, Zimmerman ME, Gorno-Tempini ML, Kramer JH -
Crossed cerebellar diaschisis on 18F-FDG PET: Frequency across neurodegenerative syndromes and association with 11C-PIB and 18F-Flortaucipir.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2021 Provost K, La Joie R, Strom A, Iaccarino L, Edwards L, Mellinger TJ, Pham J, Baker SL, Miller BL, Jagust WJ, Rabinovici GD -
Detecting Alzheimer's disease biomarkers with a brief tablet-based cognitive battery: sensitivity to Aβ and tau PET.
Alzheimer's research & therapy 2021 Tsoy E, Strom A, Iaccarino L, Erlhoff SJ, Goode CA, Rodriguez AM, Rabinovici GD, Miller BL, Kramer JH, Rankin KP, La Joie R, Possin KL -
Association Between Ambient Air Pollution and Amyloid Positron Emission Tomography Positivity in Older Adults With Cognitive Impairment.
JAMA neurology 2021 Iaccarino L, La Joie R, Lesman-Segev OH, Lee E, Hanna L, Allen IE, Hillner BE, Siegel BA, Whitmer RA, Carrillo MC, Gatsonis C, Rabinovici GD -
Association of remote mild traumatic brain injury with cortical amyloid burden in clinically normal older adults.
Brain imaging and behavior 2021 Asken BM, Mantyh WG, La Joie R, Strom A, Casaletto KB, Staffaroni AM, Apple AC, Lindbergh CA, Iaccarino L, You M, Grant H, Fonseca C, Windon C, Younes K, Tanner J, Rabinovici GD, Kramer JH, Gardner RC -
Comparing ATN-T designation by tau PET visual reads, tau PET quantification, and CSF PTau181 across three cohorts.
European journal of nuclear medicine and molecular imaging 2021 Provost K, Iaccarino L, Soleimani-Meigooni DN, Baker S, Edwards L, Eichenlaub U, Hansson O, Jagust W, Janabi M, La Joie R, Lesman-Segev O, Mellinger TJ, Miller BL, Ossenkoppele R, Pham J, Smith R, … -
Plasma Glial Fibrillary Acidic Protein Levels Differ Along the Spectra of Amyloid Burden and Clinical Disease Stage.
Journal of Alzheimer's disease : JAD 2021 Asken BM, Elahi FM, La Joie R, Strom A, Staffaroni AM, Lindbergh CA, Apple AC, You M, Weiner-Light S, Brathaban N, Fernandes N, Karydas A, Wang P, Rojas JC, Boxer AL, Miller BL, Rabinovici GD, Kramer … -
Spatial Relationships between Molecular Pathology and Neurodegeneration in the Alzheimer's Disease Continuum.
Cerebral cortex (New York, N.Y. : 1991) 2021 Iaccarino L, La Joie R, Edwards L, Strom A, Schonhaut DR, Ossenkoppele R, Pham J, Mellinger T, Janabi M, Baker SL, Soleimani-Meigooni D, Rosen HJ, Miller BL, Jagust WJ, Rabinovici GD -
Diagnostic Accuracy of Amyloid versus 18 F-Fluorodeoxyglucose Positron Emission Tomography in Autopsy-Confirmed Dementia.
Annals of neurology 2020 Lesman-Segev OH, La Joie R, Iaccarino L, Lobach I, Rosen HJ, Seo SW, Janabi M, Baker SL, Edwards L, Pham J, Olichney J, Boxer A, Huang E, Gorno-Tempini M, DeCarli C, Hepker M, Hwang JL, Miller BL, … -
18F-flortaucipir PET to autopsy comparisons in Alzheimer's disease and other neurodegenerative diseases.
Brain : a journal of neurology 2020 Soleimani-Meigooni DN, Iaccarino L, La Joie R, Baker S, Bourakova V, Boxer AL, Edwards L, Eser R, Gorno-Tempini ML, Jagust WJ, Janabi M, Kramer JH, Lesman-Segev OH, Mellinger T, Miller BL, Pham J, … -
Evaluation of a visual interpretation method for tau-PET with 18F-flortaucipir.
Alzheimer's & dementia (Amsterdam, Netherlands) 2020 Sonni I, Lesman Segev OH, Baker SL, Iaccarino L, Korman D, Rabinovici GD, Jagust WJ, Landau SM, La Joie R, Alzheimer's Disease Neuroimaging Initiative -
The impact of demographic, clinical, genetic, and imaging variables on tau PET status.
European journal of nuclear medicine and molecular imaging 2020 Ossenkoppele R, Leuzy A, Cho H, Sudre CH, Strandberg O, Smith R, Palmqvist S, Mattsson-Carlgren N, Olsson T, Jögi J, Stormrud E, Ryu YH, Choi JY, Alzheimer’s Disease Neuroimaging Initiative, PREVENT-… -
Plasma Tau and Neurofilament Light in Frontotemporal Lobar Degeneration and Alzheimer Disease.
Neurology 2020 Illán-Gala I, Lleo A, Karydas A, Staffaroni AM, Zetterberg H, Sivasankaran R, Grinberg LT, Spina S, Kramer JH, Ramos EM, Coppola G, La Joie R, Rabinovici GD, Perry DC, Gorno-Tempini ML, Seeley WW, … -
Investigating the clinico-anatomical dissociation in the behavioral variant of Alzheimer disease.
Alzheimer's research & therapy 2020 Singleton EH, Pijnenburg YAL, Sudre CH, Groot C, Kochova E, Barkhof F, La Joie R, Rosen HJ, Seeley WW, Miller B, Cardoso MJ, Papma J, Scheltens P, Rabinovici GD, Ossenkoppele R -
Hippocampal subfield volumetry from structural isotropic 1 mm3 MRI scans: A note of caution.
Human brain mapping 2020 Wisse LEM, Chételat G, Daugherty AM, de Flores R, la Joie R, Mueller SG, Stark CEL, Wang L, Yushkevich PA, Berron D, Raz N, Bakker A, Olsen RK, Carr VA -
Worth the Wait: Delayed Recall after 1 Week Predicts Cognitive and Medial Temporal Lobe Trajectories in Older Adults.
Journal of the International Neuropsychological Society : JINS 2020 Lindbergh CA, Walker N, La Joie R, Weiner-Light S, Staffaroni AM, Casaletto KB, Elahi F, Walters SM, You M, Cotter D, Asken B, Apple AC, Tsoy E, Neuhaus J, Fonseca C, Wolf A, Cobigo Y, Rosen H, Kramer… -
Symptomatic amyloid-related imaging abnormalities in an APOE ε4/ε4 patient treated with aducanumab.
Alzheimer's & dementia (Amsterdam, Netherlands) 2020 VandeVrede L, Gibbs DM, Koestler M, La Joie R, Ljubenkov PA, Provost K, Soleimani-Meigooni D, Strom A, Tsoy E, Rabinovici GD, Boxer AL -
Sex-related differences in the relationship between β-amyloid and cognitive trajectories in older adults.
Neuropsychology 2020 Lindbergh CA, Casaletto KB, Staffaroni AM, La Joie R, Iaccarino L, Edwards L, Tsoy E, Elahi F, Walters SM, Cotter D, You M, Apple AC, Asken B, Neuhaus J, Rexach JE, Wojta KJ, Rabinovici G, Kramer JH, … -
Normalization of CSF pTau measurement by Aβ40 improves its performance as a biomarker of Alzheimer's disease.
Alzheimer's research & therapy 2020 Guo T, Korman D, La Joie R, Shaw LM, Trojanowski JQ, Jagust WJ, Landau SM, Alzheimer’s Disease Neuroimaging Initiative -
Latent atrophy factors related to phenotypical variants of posterior cortical atrophy.
Neurology 2020 Groot C, Yeo BTT, Vogel JW, Zhang X, Sun N, Mormino EC, Pijnenburg YAL, Miller BL, Rosen HJ, La Joie R, Barkhof F, Scheltens P, van der Flier WM, Rabinovici GD, Ossenkoppele R -
BHA-CS: A novel cognitive composite for Alzheimer's disease and related disorders.
Alzheimer's & dementia (Amsterdam, Netherlands) 2020 Tsoy E, Erlhoff SJ, Goode CA, Dorsman KA, Kanjanapong S, Lindbergh CA, La Joie R, Strom A, Rabinovici GD, Lanata SC, Miller BL, Tomaszewski Farias SE, Kramer JH, Rankin KP, Possin KL -
Assessment of Demographic, Genetic, and Imaging Variables Associated With Brain Resilience and Cognitive Resilience to Pathological Tau in Patients With Alzheimer Disease.
JAMA neurology 2020 Ossenkoppele R, Lyoo CH, Jester-Broms J, Sudre CH, Cho H, Ryu YH, Choi JY, Smith R, Strandberg O, Palmqvist S, Kramer J, Boxer AL, Gorno-Tempini ML, Miller BL, La Joie R, Rabinovici GD, Hansson O -
An update on blood-based biomarkers for non-Alzheimer neurodegenerative disorders.
Nature reviews. Neurology 2020 Ashton NJ, Hye A, Rajkumar AP, Leuzy A, Snowden S, Suárez-Calvet M, Karikari TK, Schöll M, La Joie R, Rabinovici GD, Höglund K, Ballard C, Hortobágyi T, Svenningsson P, Blennow K, Zetterberg H, … -
Tau Positron Emission Tomographic Findings in a Former US Football Player With Pathologically Confirmed Chronic Traumatic Encephalopathy.
JAMA neurology 2020 Mantyh WG, Spina S, Lee A, Iaccarino L, Soleimani-Meigooni D, Tsoy E, Mellinger TJ, Grant H, Vandevrede L, La Joie R, Lesman-Segev O, Gaus S, Possin KL, Grinberg LT, Miller BL, Seeley WW, Rabinovici … -
Temporal variant of frontotemporal dementia in C9orf72 repeat expansion carriers: two case studies.
Brain imaging and behavior 2020 Caso F, Agosta F, Magnani G, Cardamone R, Borghesani V, Miller Z, Riva N, La Joie R, Coppola G, Grinberg LT, Seeley WW, Miller BL, Gorno-Tempini ML, Filippi M -
Diagnostic value of plasma phosphorylated tau181 in Alzheimer's disease and frontotemporal lobar degeneration.
Nature medicine 2020 Thijssen EH, La Joie R, Wolf A, Strom A, Wang P, Iaccarino L, Bourakova V, Cobigo Y, Heuer H, Spina S, VandeVrede L, Chai X, Proctor NK, Airey DC, Shcherbinin S, Duggan Evans C, Sims JR, Zetterberg H,… -
Association of Cognitive and Behavioral Features Between Adults With Tuberous Sclerosis and Frontotemporal Dementia.
JAMA neurology 2020 Liu AJ, Staffaroni AM, Rojas-Martinez JC, Olney NT, Alquezar-Burillo C, Ljubenkov PA, La Joie R, Fong JC, Taylor J, Karydas A, Ramos EM, Coppola G, Boxer AL, Rabinovici GD, Miller BL, Kao AW -
A molecular gradient along the longitudinal axis of the human hippocampus informs large-scale behavioral systems.
Nature communications 2020 Vogel JW, La Joie R, Grothe MJ, Diaz-Papkovich A, Doyle A, Vachon-Presseau E, Lepage C, Vos de Wael R, Thomas RA, Iturria-Medina Y, Bernhardt B, Rabinovici GD, Evans AC -
Morphometric network differences in ageing versus Alzheimer's disease dementia.
Brain : a journal of neurology 2020 Pichet Binette A, Gonneaud J, Vogel JW, La Joie R, Rosa-Neto P, Collins DL, Poirier J, Breitner JCS, Villeneuve S, Vachon-Presseau E, Alzheimer’s Disease Neuroimaging Initiative, PREVENT-AD Research … -
Plasma biomarkers of astrocytic and neuronal dysfunction in early- and late-onset Alzheimer's disease.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2020 Elahi FM, Casaletto KB, La Joie R, Walters SM, Harvey D, Wolf A, Edwards L, Rivera-Contreras W, Karydas A, Cobigo Y, Rosen HJ, DeCarli C, Miller BL, Rabinovici GD, Kramer JH -
Spatial patterns of tau deposition are associated with amyloid, ApoE, sex, and cognitive decline in older adults.
European journal of nuclear medicine and molecular imaging 2020 Pereira JB, Harrison TM, La Joie R, Baker SL, Jagust WJ -
Distinct tau PET patterns in atrophy-defined subtypes of Alzheimer's disease.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2020 Ossenkoppele R, Lyoo CH, Sudre CH, van Westen D, Cho H, Ryu YH, Choi JY, Smith R, Strandberg O, Palmqvist S, Westman E, Tsai R, Kramer J, Boxer AL, Gorno-Tempini ML, La Joie R, Miller BL, Rabinovici … -
Plasma Glial Fibrillary Acidic Protein Levels Differ Along the Spectra of Amyloid Burden and Clinical Disease Stage.
Journal of Alzheimer's disease : JAD 2020 Asken BM, Elahi FM, La Joie R, Strom A, Staffaroni AM, Lindbergh CA, Apple AC, You M, Weiner-Light S, Brathaban N, Fernandes N, Karydas A, Wang P, Rojas JC, Boxer AL, Miller BL, Rabinovici GD, Kramer … -
Cortical developmental abnormalities in logopenic variant primary progressive aphasia with dyslexia.
Brain communications 2019 Miller ZA, Spina S, Pakvasa M, Rosenberg L, Watson C, Mandelli ML, Paredes MF, Joie R, Rabinovici GD, Rosen HJ, Grinberg LT, Huang EJ, Miller BL, Seeley WW, Gorno-Tempini ML -
Tau PET and multimodal brain imaging in patients at risk for chronic traumatic encephalopathy.
NeuroImage. Clinical 2019 Lesman-Segev OH, La Joie R, Stephens ML, Sonni I, Tsai R, Bourakova V, Visani AV, Edwards L, O'Neil JP, Baker SL, Gardner RC, Janabi M, Chaudhary K, Perry DC, Kramer JH, Miller BL, Jagust WJ, … -
Alzheimer's pathology targets distinct memory networks in the ageing brain.
Brain : a journal of neurology 2019 Maass A, Berron D, Harrison TM, Adams JN, La Joie R, Baker S, Mellinger T, Bell RK, Swinnerton K, Inglis B, Rabinovici GD, Düzel E, Jagust WJ -
Cross-sectional and longitudinal characterization of SCD patients recruited from the community versus from a memory clinic: subjective cognitive decline, psychoaffective factors, cognitive performances, and atrophy progression over time.
Alzheimer's research & therapy 2019 Kuhn E, Moulinet I, Perrotin A, La Joie R, Landeau B, Tomadesso C, Bejanin A, Sherif S, De La Sayette V, Desgranges B, Vivien D, Poisnel G, Chételat G -
Progress update from the hippocampal subfields group.
Alzheimer's & dementia (Amsterdam, Netherlands) 2019 Olsen RK, Carr VA, Daugherty AM, La Joie R, Amaral RSC, Amunts K, Augustinack JC, Bakker A, Bender AR, Berron D, Boccardi M, Bocchetta M, Burggren AC, Chakravarty MM, Chételat G, de Flores R, DeKraker… -
An Opioid-Related Amnestic Syndrome With Persistent Effects on Hippocampal Structure and Function.
The Journal of neuropsychiatry and clinical neurosciences 2019 Butler PM, Barash JA, Casaletto KB, Cotter DL, La Joie R, Geschwind MD, Rosen HJ, Kramer JH, Miller BL -
Medial Temporal Lobe Disconnection and Hyperexcitability Across Alzheimer's Disease Stages.
Journal of Alzheimer's disease reports 2019 Pasquini L, Rahmani F, Maleki-Balajoo S, La Joie R, Zarei M, Sorg C, Drzezga A, Tahmasian M -
Tau covariance patterns in Alzheimer's disease patients match intrinsic connectivity networks in the healthy brain.
NeuroImage. Clinical 2019 Ossenkoppele R, Iaccarino L, Schonhaut DR, Brown JA, La Joie R, O'Neil JP, Janabi M, Baker SL, Kramer JH, Gorno-Tempini ML, Miller BL, Rosen HJ, Seeley WW, Jagust WJ, Rabinovici GD -
Distinct Interplay Between Atrophy and Hypometabolism in Alzheimer's Versus Semantic Dementia.
Cerebral cortex (New York, N.Y. : 1991) 2019 Bejanin A, La Joie R, Landeau B, Belliard S, de La Sayette V, Eustache F, Desgranges B, Chételat G -
Atypical clinical features associated with mixed pathology in a case of non-fluent variant primary progressive aphasia.
Neurocase 2019 De Leon J, Mandelli ML, Nolan A, Miller ZA, Mead C, Watson C, Welch AE, Henry ML, Bourakova V, La Joie R, Bajorek LP, Grinberg L, Rabinovici G, Miller BL, Gorno-Tempini ML -
Effect of Off-Target Binding on 18F-Flortaucipir Variability in Healthy Controls Across the Life Span.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2019 Baker SL, Harrison TM, Maass A, La Joie R, Jagust WJ -
18F-flortaucipir (AV-1451) tau PET in frontotemporal dementia syndromes.
Alzheimer's research & therapy 2019 Tsai RM, Bejanin A, Lesman-Segev O, LaJoie R, Visani A, Bourakova V, O'Neil JP, Janabi M, Baker S, Lee SE, Perry DC, Bajorek L, Karydas A, Spina S, Grinberg LT, Seeley WW, Ramos EM, Coppola G, Gorno-… -
Is there a specific memory signature associated with Aβ-PET positivity in patients with amnestic mild cognitive impairment?
Neurobiology of aging 2019 Tomadesso C, Gonneaud J, Egret S, Perrotin A, Pélerin A, de Flores R, de la Sayette V, Desgranges B, Chételat G, La Joie R -
Longitudinal tau accumulation and atrophy in aging and alzheimer disease.
Annals of neurology 2019 Harrison TM, La Joie R, Maass A, Baker SL, Swinnerton K, Fenton L, Mellinger TJ, Edwards L, Pham J, Miller BL, Rabinovici GD, Jagust WJ -
The SCD-Well randomized controlled trial: Effects of a mindfulness-based intervention versus health education on mental health in patients with subjective cognitive decline (SCD).
Alzheimer's & dementia (New York, N. Y.) 2018 Marchant NL, Barnhofer T, Klimecki OM, Poisnel G, Lutz A, Arenaza-Urquijo E, Collette F, Wirth M, Schild AK, Coll-Padrós N, Reyrolle L, Horney D, Krolak-Salmon P, Molinuevo JL, Walker Z, Maillard A, … -
Superior explicit memory despite severe developmental amnesia: In-depth case study and neural correlates.
Hippocampus 2018 Jonin PY, Besson G, La Joie R, Pariente J, Belliard S, Barillot C, Barbeau EJ -
Multisite study of the relationships between antemortem [11C]PIB-PET Centiloid values and postmortem measures of Alzheimer's disease neuropathology.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2018 La Joie R, Ayakta N, Seeley WW, Borys E, Boxer AL, DeCarli C, Doré V, Grinberg LT, Huang E, Hwang JH, Ikonomovic MD, Jack C, Jagust WJ, Jin LW, Klunk WE, Kofler J, Lesman-Segev OH, Lockhart SN, Lowe … -
Discriminative Accuracy of [18F]flortaucipir Positron Emission Tomography for Alzheimer Disease vs Other Neurodegenerative Disorders.
JAMA 2018 Ossenkoppele R, Rabinovici GD, Smith R, Cho H, Schöll M, Strandberg O, Palmqvist S, Mattsson N, Janelidze S, Santillo A, Ohlsson T, Jögi J, Tsai R, La Joie R, Kramer J, Boxer AL, Gorno-Tempini ML, … -
Brain properties predict proximity to symptom onset in sporadic Alzheimer's disease.
Brain : a journal of neurology 2018 Vogel JW, Vachon-Presseau E, Pichet Binette A, Tam A, Orban P, La Joie R, Savard M, Picard C, Poirier J, Bellec P, Breitner JCS, Villeneuve S, Alzheimer’s Disease Neuroimaging Initiative* and the … -
Associations between [18F]AV1451 tau PET and CSF measures of tau pathology in a clinical sample.
Neurology 2017 La Joie R, Bejanin A, Fagan AM, Ayakta N, Baker SL, Bourakova V, Boxer AL, Cha J, Karydas A, Jerome G, Maass A, Mensing A, Miller ZA, O'Neil JP, Pham J, Rosen HJ, Tsai R, Visani AV, Miller BL, Jagust … -
Tau pathology and neurodegeneration contribute to cognitive impairment in Alzheimer's disease.
Brain : a journal of neurology 2017 Bejanin A, Schonhaut DR, La Joie R, Kramer JH, Baker SL, Sosa N, Ayakta N, Cantwell A, Janabi M, Lauriola M, O'Neil JP, Gorno-Tempini ML, Miller ZA, Rosen HJ, Miller BL, Jagust WJ, Rabinovici GD -
Regional patterns of gray matter volume, hypometabolism, and beta-amyloid in groups at risk of Alzheimer's disease.
Neurobiology of aging 2017 Wirth M, Bejanin A, La Joie R, Arenaza-Urquijo EM, Gonneaud J, Landeau B, Perrotin A, Mézenge F, de La Sayette V, Desgranges B, Chételat G -
Subjective cognitive decline and β-amyloid burden predict cognitive change in healthy elderly.
Neurology 2017 Vogel JW, Varga Doležalová M, La Joie R, Marks SM, Schwimmer HD, Landau SM, Jagust WJ -
Association between educational attainment and amyloid deposition across the spectrum from normal cognition to dementia: neuroimaging evidence for protection and compensation.
Neurobiology of aging 2017 Arenaza-Urquijo EM, Bejanin A, Gonneaud J, Wirth M, La Joie R, Mutlu J, Gaubert M, Landeau B, de la Sayette V, Eustache F, Chételat G -
Comparison of multiple tau-PET measures as biomarkers in aging and Alzheimer's disease.
NeuroImage 2017 Maass A, Landau S, Baker SL, Horng A, Lockhart SN, La Joie R, Rabinovici GD, Jagust WJ, Alzheimer's Disease Neuroimaging Initiative -
Elevated 18F-AV-1451 PET tracer uptake detected in incidental imaging findings.
Neurology 2017 Lockhart SN, Ayakta N, Winer JR, La Joie R, Rabinovici GD, Jagust WJ -
Qualitative and quantitative assessment of self-reported cognitive difficulties in nondemented elders: Association with medical help seeking, cognitive deficits, and β-amyloid imaging.
Alzheimer's & dementia (Amsterdam, Netherlands) 2016 La Joie R, Perrotin A, Egret S, Pasquier F, Tomadesso C, Mézenge F, Desgranges B, de La Sayette V, Chételat G -
Distinct white matter injury associated with medial temporal lobe atrophy in Alzheimer's versus semantic dementia.
Human brain mapping 2016 Bejanin A, Desgranges B, La Joie R, Landeau B, Perrotin A, Mézenge F, Belliard S, de La Sayette V, Eustache F, Chételat G -
A harmonized segmentation protocol for hippocampal and parahippocampal subregions: Why do we need one and what are the key goals?
Hippocampus 2016 Wisse LEM, Daugherty AM, Olsen RK, Berron D, Carr VA, Stark CEL, Amaral RSC, Amunts K, Augustinack JC, Bender AR, Bernstein JD, Boccardi M, Bocchetta M, Burggren A, Chakravarty MM, Chupin M, Ekstrom A… -
Subjective cognitive decline in cognitively normal elders from the community or from a memory clinic: Differential affective and imaging correlates.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2016 Perrotin A, La Joie R, de La Sayette V, Barré L, Mézenge F, Mutlu J, Guilloteau D, Egret S, Eustache F, Chételat G -
Atrophy, hypometabolism and clinical trajectories in patients with amyloid-negative Alzheimer's disease.
Brain : a journal of neurology 2016 Chételat G, Ossenkoppele R, Villemagne VL, Perrotin A, Landeau B, Mézenge F, Jagust WJ, Dore V, Miller BL, Egret S, Seeley WW, van der Flier WM, La Joie R, Ames D, van Berckel BN, Scheltens P, Barkhof… -
Hippocampal Subfield Volumetry and 3D Surface Mapping in Subjective Cognitive Decline.
Journal of Alzheimer's disease : JAD 2015 Perrotin A, de Flores R, Lamberton F, Poisnel G, La Joie R, de la Sayette V, Mézenge F, Tomadesso C, Landeau B, Desgranges B, Chételat G -
FDG-PET Contributions to the Pathophysiology of Memory Impairment.
Neuropsychology review 2015 Segobin S, La Joie R, Ritz L, Beaunieux H, Desgranges B, Chételat G, Pitel AL, Eustache F -
Structural imaging of hippocampal subfields in healthy aging and Alzheimer's disease.
Neuroscience 2015 de Flores R, La Joie R, Chételat G -
Atrophy patterns in early clinical stages across distinct phenotypes of Alzheimer's disease.
Human brain mapping 2015 Ossenkoppele R, Cohn-Sheehy BI, La Joie R, Vogel JW, Möller C, Lehmann M, van Berckel BN, Seeley WW, Pijnenburg YA, Gorno-Tempini ML, Kramer JH, Barkhof F, Rosen HJ, van der Flier WM, Jagust WJ, … -
Cognitive and Brain Profiles Associated with Current Neuroimaging Biomarkers of Preclinical Alzheimer's Disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2015 Besson FL, La Joie R, Doeuvre L, Gaubert M, Mézenge F, Egret S, Landeau B, Barré L, Abbas A, Ibazizene M, de La Sayette V, Desgranges B, Eustache F, Chételat G -
Anosognosia in Alzheimer disease: Disconnection between memory and self-related brain networks.
Annals of neurology 2015 Perrotin A, Desgranges B, Landeau B, Mézenge F, La Joie R, Egret S, Pélerin A, de la Sayette V, Eustache F, Chételat G -
The behavioural/dysexecutive variant of Alzheimer's disease: clinical, neuroimaging and pathological features.
Brain : a journal of neurology 2015 Ossenkoppele R, Pijnenburg YA, Perry DC, Cohn-Sheehy BI, Scheltens NM, Vogel JW, Kramer JH, van der Vlies AE, La Joie R, Rosen HJ, van der Flier WM, Grinberg LT, Rozemuller AJ, Huang EJ, van Berckel … -
Why musical memory can be preserved in advanced Alzheimer's disease.
Brain : a journal of neurology 2015 Jacobsen JH, Stelzer J, Fritz TH, Chételat G, La Joie R, Turner R -
Existing Pittsburgh Compound-B positron emission tomography thresholds are too high: statistical and pathological evaluation.
Brain : a journal of neurology 2015 Villeneuve S, Rabinovici GD, Cohn-Sheehy BI, Madison C, Ayakta N, Ghosh PM, La Joie R, Arthur-Bentil SK, Vogel JW, Marks SM, Lehmann M, Rosen HJ, Reed B, Olichney J, Boxer AL, Miller BL, Borys E, Jin … -
Are AD-Typical Regions the Convergence Point of Multiple Pathologies?
Frontiers in aging neuroscience 2015 Villeneuve S, Wirth M, La Joie R -
Quantitative comparison of 21 protocols for labeling hippocampal subfields and parahippocampal subregions in in vivo MRI: towards a harmonized segmentation protocol.
NeuroImage 2015 Yushkevich PA, Amaral RS, Augustinack JC, Bender AR, Bernstein JD, Boccardi M, Bocchetta M, Burggren AC, Carr VA, Chakravarty MM, Chételat G, Daugherty AM, Davachi L, Ding SL, Ekstrom A, Geerlings MI,… -
Effects of age and Alzheimer's disease on hippocampal subfields: comparison between manual and FreeSurfer volumetry.
Human brain mapping 2014 de Flores R, La Joie R, Landeau B, Perrotin A, Mézenge F, de La Sayette V, Eustache F, Desgranges B, Chételat G -
Imaging brain effects of APOE4 in cognitively normal individuals across the lifespan.
Neuropsychology review 2014 Fouquet M, Besson FL, Gonneaud J, La Joie R, Chételat G -
Toward a better understanding of the injured hippocampus: multimodal imaging in functionally relevant substructures.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 La Joie R -
Gene-environment interactions: lifetime cognitive activity, APOE genotype, and β-amyloid burden.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Wirth M, Villeneuve S, La Joie R, Marks SM, Jagust WJ -
Intrinsic connectivity identifies the hippocampus as a main crossroad between Alzheimer's and semantic dementia-targeted networks.
Neuron 2014 La Joie R, Landeau B, Perrotin A, Bejanin A, Egret S, Pélerin A, Mézenge F, Belliard S, de La Sayette V, Eustache F, Desgranges B, Chételat G -
Hippocampal subfield volumetry in mild cognitive impairment, Alzheimer's disease and semantic dementia.
NeuroImage. Clinical 2013 La Joie R, Perrotin A, de La Sayette V, Egret S, Doeuvre L, Belliard S, Eustache F, Desgranges B, Chételat G -
Readiness to change and brain damage in patients with chronic alcoholism.
Psychiatry research 2013 Le Berre AP, Rauchs G, La Joie R, Segobin S, Mézenge F, Boudehent C, Vabret F, Viader F, Eustache F, Pitel AL, Beaunieux H -
Relationships between years of education and gray matter volume, metabolism and functional connectivity in healthy elders.
NeuroImage 2013 Arenaza-Urquijo EM, Landeau B, La Joie R, Mevel K, Mézenge F, Perrotin A, Desgranges B, Bartrés-Faz D, Eustache F, Chételat G -
Amyloid imaging in cognitively normal individuals, at-risk populations and preclinical Alzheimer's disease.
NeuroImage. Clinical 2013 Chételat G, La Joie R, Villain N, Perrotin A, de La Sayette V, Eustache F, Vandenberghe R -
Impaired decision-making and brain shrinkage in alcoholism.
European psychiatry : the journal of the Association of European Psychiatrists 2012 Le Berre AP, Rauchs G, La Joie R, Mézenge F, Boudehent C, Vabret F, Segobin S, Viader F, Allain P, Eustache F, Pitel AL, Beaunieux H -
Region-specific hierarchy between atrophy, hypometabolism, and β-amyloid (Aβ) load in Alzheimer's disease dementia.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012 La Joie R, Perrotin A, Barré L, Hommet C, Mézenge F, Ibazizene M, Camus V, Abbas A, Landeau B, Guilloteau D, de La Sayette V, Eustache F, Desgranges B, Chételat G -
Age effect on the default mode network, inner thoughts, and cognitive abilities.
Neurobiology of aging 2012 Mevel K, Landeau B, Fouquet M, La Joie R, Villain N, Mézenge F, Perrotin A, Eustache F, Desgranges B, Chételat G -
The hippocampus remains activated over the long term for the retrieval of truly episodic memories.
PloS one 2012 Harand C, Bertran F, La Joie R, Landeau B, Mézenge F, Desgranges B, Peigneux P, Eustache F, Rauchs G -
Using PET with 18F-AV-45 (florbetapir) to quantify brain amyloid load in a clinical environment.
European journal of nuclear medicine and molecular imaging 2012 Camus V, Payoux P, Barré L, Desgranges B, Voisin T, Tauber C, La Joie R, Tafani M, Hommet C, Chételat G, Mondon K, de La Sayette V, Cottier JP, Beaufils E, Ribeiro MJ, Gissot V, Vierron E, Vercouillie… -
Role of hippocampal CA1 atrophy in memory encoding deficits in amnestic Mild Cognitive Impairment.
NeuroImage 2011 Fouquet M, Desgranges B, La Joie R, Rivière D, Mangin JF, Landeau B, Mézenge F, Pélerin A, de La Sayette V, Viader F, Baron JC, Eustache F, Chételat G -
When music and long-term memory interact: effects of musical expertise on functional and structural plasticity in the hippocampus.
PloS one 2010 Groussard M, La Joie R, Rauchs G, Landeau B, Chételat G, Viader F, Desgranges B, Eustache F, Platel H -
Differential effect of age on hippocampal subfields assessed using a new high-resolution 3T MR sequence.
NeuroImage 2010 La Joie R, Fouquet M, Mézenge F, Landeau B, Villain N, Mevel K, Pélerin A, Eustache F, Desgranges B, Chételat G