Raul Andino-Pavlovsky, PhD
Professor
Microbiology and Immunology
School of Medicine

Publications (36)

Top publication keywords:
Poliovirus Vaccine, OralVirus ReplicationLife History TraitsRNA VirusesVaccines, AttenuatedReceptors, Pattern RecognitionPoliovirusEnterovirus InfectionsEnterovirusPoliomyelitisVirusesHost-Pathogen InteractionsCommunicable DiseasesBiological EvolutionViral Proteins

• Now you see me, now you don't: What and how viral RNAs are detected by cytoplasmic pattern-recognition receptors.
  Molecular cell 2025 Andino R, Darling D
• A tradeoff between enterovirus A71 particle stability and cell entry.
  Nature communications 2023 Catching A, Te Yeh M, Bianco S, Capponi S, Andino R
• Genetic stabilization of attenuated oral vaccines against poliovirus types 1 and 3.
  Nature 2023 Yeh MT, Smith M, Carlyle S, Konopka-Anstadt JL, Burns CC, Konz J, Andino R, Macadam A
• Reconsidering life history theory amid infectious diseases.
  Trends in ecology & evolution 2023 Lidsky PV, Yuan J, Andino R
• Fluorogenic reporter enables identification of compounds that inhibit SARS-CoV-2.
  Nature microbiology 2023 Yang J, Xiao Y, Lidsky PV, Wu CT, Bonser LR, Peng S, Garcia-Knight MA, Tassetto M, Chung CI, Li X, Nakayama T, Lee IT, Nayak JV, Ghias K, Hargett KL, Shoichet BK, Erle DJ, Jackson PK, Andino R, Shu X

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• SARS-CoV-2 replication in airway epithelia requires motile cilia and microvillar reprogramming.
  Cell 2022 Wu CT, Lidsky PV, Xiao Y, Cheng R, Lee IT, Nakayama T, Jiang S, He W, Demeter J, Knight MG, Turn RE, Rojas-Hernandez LS, Ye C, Chiem K, Shon J, Martinez-Sobrido L, Bertozzi CR, Nolan GP, Nayak JV, …
• Is Aging an Inevitable Characteristic of Organic Life or an Evolutionary Adaptation?
  Biochemistry. Biokhimiia 2022 Lidsky PV, Yuan J, Rulison JM, Andino-Pavlovsky R
• Could aging evolve as a pathogen control strategy?
  Trends in ecology & evolution 2022 Lidsky PV, Andino R
• A defective viral genome strategy elicits broad protective immunity against respiratory viruses.
  Cell 2021 Xiao Y, Lidsky PV, Shirogane Y, Aviner R, Wu CT, Li W, Zheng W, Talbot D, Catching A, Doitsh G, Su W, Gekko CE, Nayak A, Ernst JD, Brodsky L, Brodsky E, Rousseau E, Capponi S, Bianco S, Nakamura R, …
• Author Correction: Cotranslational prolyl hydroxylation is essential for flavivirus biogenesis.
  Nature 2021 Aviner R, Li KH, Frydman J, Andino R
• Cotranslational prolyl hydroxylation is essential for flavivirus biogenesis.
  Nature 2021 Aviner R, Li KH, Frydman J, Andino R
• Examining the interplay between face mask usage, asymptomatic transmission, and social distancing on the spread of COVID-19.
  Scientific reports 2021 Catching A, Capponi S, Yeh MT, Bianco S, Andino R
• SARS-CoV-2 infects human pancreatic β cells and elicits β cell impairment.
  Cell metabolism 2021 Wu CT, Lidsky PV, Xiao Y, Lee IT, Cheng R, Nakayama T, Jiang S, Demeter J, Bevacqua RJ, Chang CA, Whitener RL, Stalder AK, Zhu B, Chen H, Goltsev Y, Tzankov A, Nayak JV, Nolan GP, Matter MS, Andino R,…
• Transmission, infectivity, and neutralization of a spike L452R SARS-CoV-2 variant.
  Cell 2021 Deng X, Garcia-Knight MA, Khalid MM, Servellita V, Wang C, Morris MK, Sotomayor-González A, Glasner DR, Reyes KR, Gliwa AS, Reddy NP, Sanchez San Martin C, Federman S, Cheng J, Balcerek J, Taylor J, …
• Species-Specific Evolution of Ebola Virus during Replication in Human and Bat Cells.
  Cell reports 2020 Whitfield ZJ, Prasad AN, Ronk AJ, Kuzmin IV, Ilinykh PA, Andino R, Bukreyev A
• Epidemics as an adaptive driving force determining lifespan setpoints.
  Proceedings of the National Academy of Sciences of the United States of America 2020 Lidsky PV, Andino R
• Engineering the Live-Attenuated Polio Vaccine to Prevent Reversion to Virulence.
  Cell host & microbe 2020 Yeh MT, Bujaki E, Dolan PT, Smith M, Wahid R, Konz J, Weiner AJ, Bandyopadhyay AS, Van Damme P, De Coster I, Revets H, Macadam A, Andino R
• Enterovirus pathogenesis requires the host methyltransferase SETD3.
  Nature microbiology 2019 Diep J, Ooi YS, Wilkinson AW, Peters CE, Foy E, Johnson JR, Zengel J, Ding S, Weng KF, Laufman O, Jang G, Xu J, Young T, Verschueren E, Kobluk KJ, Elias JE, Sarnow P, Greenberg HB, Hüttenhain R, …
• Viral Generated Inter-Organelle Contacts Redirect Lipid Flux for Genome Replication.
  Cell 2019 Laufman O, Perrino J, Andino R
• Comparative Flavivirus-Host Protein Interaction Mapping Reveals Mechanisms of Dengue and Zika Virus Pathogenesis.
  Cell 2018 Shah PS, Link N, Jang GM, Sharp PP, Zhu T, Swaney DL, Johnson JR, Von Dollen J, Ramage HR, Satkamp L, Newton B, Hüttenhain R, Petit MJ, Baum T, Everitt A, Laufman O, Tassetto M, Shales M, Stevenson E,…
• A Viral Protein Restricts Drosophila RNAi Immunity by Regulating Argonaute Activity and Stability.
  Cell host & microbe 2018 Nayak A, Kim DY, Trnka MJ, Kerr CH, Lidsky PV, Stanley DJ, Rivera BM, Li KH, Burlingame AL, Jan E, Frydman J, Gross JD, Andino R
• Mechanisms and Concepts in RNA Virus Population Dynamics and Evolution.
  Annual review of virology 2018 Dolan PT, Whitfield ZJ, Andino R
• Hsp90 shapes protein and RNA evolution to balance trade-offs between protein stability and aggregation.
  Nature communications 2018 Geller R, Pechmann S, Acevedo A, Andino R, Frydman J
• Mapping the Evolutionary Potential of RNA Viruses.
  Cell host & microbe 2018 Dolan PT, Whitfield ZJ, Andino R
• The Diversity, Structure, and Function of Heritable Adaptive Immunity Sequences in the Aedes aegypti Genome.
  Current biology : CB 2017 Whitfield ZJ, Dolan PT, Kunitomi M, Tassetto M, Seetin MG, Oh S, Heiner C, Paxinos E, Andino R
• Poliovirus intrahost evolution is required to overcome tissue-specific innate immune responses.
  Nature communications 2017 Xiao Y, Dolan PT, Goldstein EF, Li M, Farkov M, Brodsky L, Andino R
• Circulating Immune Cells Mediate a Systemic RNAi-Based Adaptive Antiviral Response in Drosophila.
  Cell 2017 Tassetto M, Kunitomi M, Andino R
• Editorial overview: Viral pathogenesis: Strategies for virus survival - Acute versus persistent infections.
  Current opinion in virology 2017 Andino R, Diamond M
• The Evolutionary Pathway to Virulence of an RNA Virus.
  Cell 2017 Stern A, Yeh MT, Zinger T, Smith M, Wright C, Ling G, Nielsen R, Macadam A, Andino R
• Viral polymerases.
  Virus research 2017 Menéndez-Arias L, Andino R
• Characterization of Viral Populations by Using Circular Sequencing.
  Journal of virology 2016 Whitfield ZJ, Andino R
• RNA Recombination Enhances Adaptability and Is Required for Virus Spread and Virulence.
  Cell host & microbe 2016 Xiao Y, Rouzine IM, Bianco S, Acevedo A, Goldstein EF, Farkov M, Brodsky L, Andino R
• Viral quasispecies.
  Virology 2015 Andino R, Domingo E
• Costs and benefits of mutational robustness in RNA viruses.
  Cell reports 2014 Stern A, Bianco S, Yeh MT, Wright C, Butcher K, Tang C, Nielsen R, Andino R
• Use of host-like peptide motifs in viral proteins is a prevalent strategy in host-virus interactions.
  Cell reports 2014 Hagai T, Azia A, Babu MM, Andino R
• Rationalizing the development of live attenuated virus vaccines.
  Nature biotechnology 2010 Lauring AS, Jones JO, Andino R