Rangarajan Nadadur, MD, PhD
Clinical Fellow
Medicine
School of Medicine

Publications (22)

Top publication keywords:
Atrial FibrillationVentricular RemodelingHeart FailureTranscription FactorsEstrogen Receptor betaT-Box Domain ProteinsTranscription, GeneticEstradiolHeart RateHypertension, PulmonaryAtrioventricular NodeExtracellular MatrixGene Regulatory NetworksHomeodomain ProteinsAtrial Remodeling

• Targeting RUNX1 in Macrophages Facilitates Cardiac Recovery.
  bioRxiv : the preprint server for biology 2025 Amrute JM, Zhu A, Pai YL, Hector-Greene M, An Y, Kim KR, Sheth MU, Padmanabhan A, Lee CY, Yamawaki T, Sicklinger F, Hartman N, Bredemeyer A, Lee CJM, Xu V, Bell L, Harmon T, Shin H, Parvathaneni A, …
• A Genomic Link From Heart Failure to Atrial Fibrillation Risk: FOG2 Modulates a TBX5/GATA4-Dependent Atrial Gene Regulatory Network.
  Circulation 2024 Broman MT, Nadadur RD, Perez-Cervantes C, Burnicka-Turek O, Lazarevic S, Gams A, Laforest B, Steimle JD, Iddir S, Wang Z, Smith L, Mazurek SR, Olivey HE, Zhou P, Gadek M, Shen KM, Khan Z, Theisen JWM,…
• ETV2 primes hematoendothelial gene enhancers prior to hematoendothelial fate commitment.
  Cell reports 2023 Steimle JD, Kim C, Rowton M, Nadadur RD, Wang Z, Stocker M, Hoffmann AD, Hanson E, Kweon J, Sinha T, Choi K, Black BL, Cunningham JM, Moskowitz IP, Ikegami K
• Severe recurrence of reactive infectious mucocutaneous eruption with extensive ocular involvement in an adult due to SARS-CoV-2.
  JAAD case reports 2023 Wu D, Lee EY, Lifton J, Zullo SW, Seiger K, Nadadur R, Fox LP, Escobar DJ, Dobry AS, Yung M, Kangelaris KN, Arakaki RY
• Chamber-specific transcriptional responses in atrial fibrillation.
  JCI insight 2020 Lipovsky CE, Jimenez J, Guo Q, Li G, Yin T, Hicks SC, Bhatnagar S, Takahashi K, Zhang DM, Brumback BD, Goldsztejn U, Nadadur RD, Perez-Cervantez C, Moskowitz IP, Liu S, Zhang B, Rentschler SL

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• Epigenetic and Transcriptional Networks Underlying Atrial Fibrillation.
  Circulation research 2020 van Ouwerkerk AF, Hall AW, Kadow ZA, Lazarevic S, Reyat JS, Tucker NR, Nadadur RD, Bosada FM, Bianchi V, Ellinor PT, Fabritz L, Martin JF, de Laat W, Kirchhof P, Moskowitz IP, Christoffels VM
• ZO-1 Regulates Intercalated Disc Composition and Atrioventricular Node Conduction.
  Circulation research 2020 Dai W, Nadadur RD, Brennan JA, Smith HL, Shen KM, Gadek M, Laforest B, Wang M, Gemel J, Li Y, Zhang J, Ziman BD, Yan J, Ai X, Beyer EC, Lakata EG, Kasthuri N, Efimov IR, Broman MT, Moskowitz IP, Shen …
• Transcriptional Patterning of the Ventricular Cardiac Conduction System.
  Circulation research 2020 Burnicka-Turek O, Broman MT, Steimle JD, Boukens BJ, Petrenko NB, Ikegami K, Nadadur RD, Qiao Y, Arnolds DE, Yang XH, Patel VV, Nobrega MA, Efimov IR, Moskowitz IP
• Enhancer transcription identifies cis-regulatory elements for photoreceptor cell types.
  Development (Cambridge, England) 2020 Perez-Cervantes C, Smith LA, Nadadur RD, Hughes AEO, Wang S, Corbo JC, Cepko C, Lonfat N, Moskowitz IP
• A calcium transport mechanism for atrial fibrillation in Tbx5-mutant mice.
  eLife 2019 Dai W, Laforest B, Tyan L, Shen KM, Nadadur RD, Alvarado FJ, Mazurek SR, Lazarevic S, Gadek M, Wang Y, Li Y, Valdivia HH, Shen L, Broman MT, Moskowitz IP, Weber CR
• Estrogen rescues heart failure through estrogen receptor Beta activation.
  Biology of sex differences 2018 Iorga A, Umar S, Ruffenach G, Aryan L, Li J, Sharma S, Motayagheni N, Nadadur RD, Bopassa JC, Eghbali M
• Evolutionarily conserved Tbx5-Wnt2/2b pathway orchestrates cardiopulmonary development.
  Proceedings of the National Academy of Sciences of the United States of America 2018 Steimle JD, Rankin SA, Slagle CE, Bekeny J, Rydeen AB, Chan SS, Kweon J, Yang XH, Ikegami K, Nadadur RD, Rowton M, Hoffmann AD, Lazarevic S, Thomas W, Boyle Anderson EAT, Horb ME, Luna-Zurita L, Ho RK…
• Transcription-factor-dependent enhancer transcription defines a gene regulatory network for cardiac rhythm.
  eLife 2017 Yang XH, Nadadur RD, Hilvering CR, Bianchi V, Werner M, Mazurek SR, Gadek M, Shen KM, Goldman JA, Tyan L, Bekeny J, Hall JM, Lee N, Perez-Cervantes C, Burnicka-Turek O, Poss KD, Weber CR, de Laat W, …
• Chromatin-enriched lncRNAs can act as cell-type specific activators of proximal gene transcription.
  Nature structural & molecular biology 2017 Werner MS, Sullivan MA, Shah RN, Nadadur RD, Grzybowski AT, Galat V, Moskowitz IP, Ruthenburg AJ
• Pitx2 modulates a Tbx5-dependent gene regulatory network to maintain atrial rhythm.
  Science translational medicine 2016 Nadadur RD, Broman MT, Boukens B, Mazurek SR, Yang X, van den Boogaard M, Bekeny J, Gadek M, Ward T, Zhang M, Qiao Y, Martin JF, Seidman CE, Seidman J, Christoffels V, Efimov IR, McNally EM, Weber CR,…
• Rescue of Pressure Overload-Induced Heart Failure by Estrogen Therapy.
  Journal of the American Heart Association 2016 Iorga A, Li J, Sharma S, Umar S, Bopassa JC, Nadadur RD, Centala A, Ren S, Saito T, Toro L, Wang Y, Stefani E, Eghbali M
• Cardiac structural and hemodynamic changes associated with physiological heart hypertrophy of pregnancy are reversed postpartum.
  Journal of applied physiology (Bethesda, Md. : 1985) 2012 Umar S, Nadadur R, Iorga A, Amjedi M, Matori H, Eghbali M
• New frontiers in heart hypertrophy during pregnancy.
  American journal of cardiovascular disease 2012 Li J, Umar S, Amjedi M, Iorga A, Sharma S, Nadadur RD, Regitz-Zagrosek V, Eghbali M
• Genistein, a soy phytoestrogen, reverses severe pulmonary hypertension and prevents right heart failure in rats.
  Hypertension (Dallas, Tex. : 1979) 2012 Matori H, Umar S, Nadadur RD, Sharma S, Partow-Navid R, Afkhami M, Amjedi M, Eghbali M
• Reverse right ventricular structural and extracellular matrix remodeling by estrogen in severe pulmonary hypertension.
  Journal of applied physiology (Bethesda, Md. : 1985) 2012 Nadadur RD, Umar S, Wong G, Eghbali M, Iorga A, Matori H, Partow-Navid R, Eghbali M
• Intralipid prevents and rescues fatal pulmonary arterial hypertension and right ventricular failure in rats.
  Hypertension (Dallas, Tex. : 1979) 2011 Umar S, Nadadur RD, Li J, Maltese F, Partownavid P, van der Laarse A, Eghbali M
• Estrogen rescues preexisting severe pulmonary hypertension in rats.
  American journal of respiratory and critical care medicine 2011 Umar S, Iorga A, Matori H, Nadadur RD, Li J, Maltese F, van der Laarse A, Eghbali M