Ralph Marcucio, PhD
Professor
Orthopaedic Surgery
School of Medicine

Websites

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• Profile at UCSF Orthopaedic Surgery (orthosurg.ucsf.edu)

Grants and Projects

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• Cell Transitions during Bone Fracture Healing, NIH, 2023-2028
• The role of continuous phenotypic variation in structural defects of the face, NIH, 2010-2026
• Transcriptional regulatory landscapes underlying FEZ Formation, NIH, 2020-2025
• A Predictive Developmental Morphospace Model of Cleft Lip, NIH, 2020-2021
• Understanding the Forces that Shape the Face, NIH, 2018-2021
• Molecular Basis of Tissue Interactions that Regulate Craniofacial Development, NIH, 2007-2018
• Effects of Aging on Macrophages and Bone Regeneration, NIH, 2013-2018
• Developmental mechanisms underlying genotype-phenotype correlations, NIH, 2011-2017
• BMP-Mediated Tissue Interactions that Pattern the Face, NIH, 2005-2007
• Cell Death in Embryonic Head Muscles, NIH, 1996-1900

Publications (218)

Top publication keywords:
Chick EmbryoBony CallusMorphogenesisHedgehog ProteinsFacial BonesDevelopmental BiologyFracture HealingFractures, BoneGene Expression Regulation, DevelopmentalFaceSkullNeural CrestBone RegenerationTibial FracturesEctoderm

• Age-related changes to macrophage subpopulations and TREM2 dysregulation characterize attenuated fracture healing in old mice.
  Aging cell 2024 Clark D, Brazina S, Miclau T, Park S, Hsieh CL, Nakamura M, Marcucio R
• A Shifting Paradigm: Transformation of Cartilage to Bone during Bone Repair.
  Journal of dental research 2022 Marcucio RS, Miclau T, Bahney CS
• Cartilage to bone transformation during fracture healing is coordinated by the invading vasculature and induction of the core pluripotency genes.
  Development (Cambridge, England) 2017 Hu DP, Ferro F, Yang F, Taylor AJ, Chang W, Miclau T, Marcucio RS, Bahney CS
• Facial Morphogenesis: Physical and Molecular Interactions Between the Brain and the Face.
  Current topics in developmental biology 2015 Marcucio R, Hallgrimsson B, Young NM
• Stem cell-derived endochondral cartilage stimulates bone healing by tissue transformation.
  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2014 Bahney CS, Hu DP, Taylor AJ, Ferro F, Britz HM, Hallgrimsson B, Johnstone B, Miclau T, Marcucio RS
• The role of oxygen during fracture healing.
  Bone 2012 Lu C, Saless N, Wang X, Sinha A, Decker S, Kazakia G, Hou H, Williams B, Swartz HM, Hunt TK, Miclau T, Marcucio RS

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• Three-dimensional cellular dynamics and mandibular morphogenesis.
  Frontiers in cell and developmental biology 2026 Dauter A, Malhi SK, Lo Vercio LD, Barretto EC, Nguyen KMT, Da Silva C, Gutierrez A, Marcucio RS, Hallgrímsson B
• Murine Progeria Model Exhibits Delayed Fracture Healing With Senescent Phenotype and Dysregulated Immune Response.
  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2026 Duke VR, Philippon MJ, Lind DRG, Kasler H, Yamaura K, Huard M, Czachor M, Hollenbeck J, Brown J, Garcia A, Matityahu JD, Fukase N, Marcucio RS, Nelson AL, Hambright WS, Snapper DM, Huard J, Bahney CS
• Age-related Delays in Osteochondral Remodeling of Fracture Healing Illustrated by Mass Spectrometry Imaging.
  bioRxiv : the preprint server for biology 2026 Schurman CA, Chandler W, Hu D, Taylor H, Tao N, Miclau T, Angel P, Marcucio R, Schilling B
• How the brain predicts the face: Teaching the brain as a co-architect of the face.
  Anatomical sciences education 2025 McBride JM, Marcucio R
• Enhanced fracture repair in p21-/- mice is mediated through increased callus mineralization.
  Bone 2025 Olsen A, Premnath P, Brunet S, Larijani L, Manske SL, Ferrie L, Duncan NA, Rancourt DE, Marcucio RS, Krawetz R
• What's New in Musculoskeletal Basic Science.
  The Journal of bone and joint surgery. American volume 2025 Bahney CS, Stoddart MJ, Miclau T, Marcucio RS
• Corrigendum to 'Blocking Kv1.3 potassium channels prevents postoperative neuroinflammation and cognitive decline without impairing wound healing in mice' (Br J Anaesth 2020; 125: 298-307).
  British journal of anaesthesia 2025 Lai IK, Valdearcos M, Morioka K, Saxena S, Feng X, Li R, Uchida Y, Lijun A, Li W, Pan J, Koliwad S, Marcucio R, Wulff H, Maze M
• Mesenchymal progenitor-derived proteoglycan 4 regulates the transdifferentiation of chondrocytes into osteoblasts during fracture healing.
  Stem cells translational medicine 2025 Ninkovic N, Corpuz JM, Stahl A, Olsen A, Unger CM, Ardebili AA, Sun H, Cha J, Kaketsis D, Manske SL, Haider IT, Marcucio RS, Schmidt TA, Jay GD, Underhill TM, Edwards WB, Rancourt DE, Biernaskie J, …
• Influence of Age on Fracture Healing in Young and Middle-Aged Mice in a Proximal Femur Fracture Model.
  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2025 Schmid T, Kanewska A, Lam C, Kalbitz M, Dieterich S, Ignatius A, Riegger J, Giger NV, Wehrle E, Marcucio RS, Miclau T, Haffner-Luntzer M
• Ultrafine-Grained Materials With Antibacterial Properties: A Novel Approach to Reducing Spinal Implant-Associated Infections.
  JOR spine 2025 Nishizawa M, Hu D, Serhan H, Saleh B, Marcucio RS, Morioka K
• A Unique Mouse Model for Quantitative Assessment of Biofilm Formation on Surgical Implants in Subcutaneous Abscess.
  Journal of visualized experiments : JoVE 2025 Nishizawa M, Saleh B, Marcucio R, Morioka K
• A bad break: mechanisms and assessment of acute and chronic pain after bone fracture.
  Pain 2025 Nishimura H, Layne J, Yamaura K, Marcucio R, Morioka K, Basbaum AI, Weinrich JAP, Bahney CS
• PBX1 and PBX3 transcription factors regulate SHH expression in the Frontonasal Ectodermal Zone through complementary mechanisms.
  PLoS genetics 2025 Mok CH, Hu D, Losa M, Risolino M, Selleri L, Marcucio RS
• Downstream branches of receptor tyrosine kinase signaling act interdependently to shape the face.
  Developmental dynamics : an official publication of the American Association of Anatomists 2025 Hanne N, Hu D, Vidal-García M, Allen C, Shakir MB, Liu W, Hallgrímsson B, Marcucio R
• Quantifying the relationship between cell proliferation and morphology during development of the face.
  Development (Cambridge, England) 2025 Lo Vercio LD, Green RM, Dauter A, Barretto EC, Vidal-García M, Devine J, Marchini M, Robertson S, Zhao X, Mahika A, Shakir MB, Guo S, Boughner JC, Szabo-Rogers H, Dean W, Lander AD, Marcucio RS, …
• CD47 is required for mesenchymal progenitor proliferation and fracture repair.
  Bone research 2025 Zondervan RL, Capobianco CA, Jenkins DC, Reicha JD, Fredrick L, Lam C, Schmanski JT, Isenberg JS, Ahn J, Marcucio RS, Hankenson KD
• Downstream branches of receptor tyrosine kinase signaling act interdependently to shape the face.
  bioRxiv : the preprint server for biology 2024 Hanne N, Hu D, Vidal-García M, Allen C, Shakir MB, Liu W, Hallgrímsson B, Marcucio R
• PBX1 and PBX3 transcription factors regulate SHH expression in the Frontonasal Ectodermal Zone through complementary mechanisms.
  bioRxiv : the preprint server for biology 2024 Mok CH, Hu D, Losa M, Risolino M, Selleri L, Marcucio RS
• Murine Progeria Model Exhibits Delayed Fracture Healing with Dysregulated Local Immune Response.
  bioRxiv : the preprint server for biology 2024 Duke VR, Philippon MJ, Lind DRG, Kasler H, Yamaura K, Huard M, Czachor M, Hollenbeck J, Brown J, Garcia A, Fukase N, Marcucio RS, Nelson AL, Hambright WS, Snapper DM, Huard J, Bahney CS
• β-catenin mRNA encapsulated in SM-102 lipid nanoparticles enhances bone formation in a murine tibia fracture repair model.
  Bioactive materials 2024 Nelson AL, Mancino C, Gao X, Choe JA, Chubb L, Williams K, Czachor M, Marcucio R, Taraballi F, Cooke JP, Huard J, Bahney C, Ehrhart N
• Genetic architecture of trait variance in craniofacial morphology.
  Genetics 2024 Andrade F, Howell L, Percival CJ, Richtsmeier JT, Marcucio RS, Hallgrímsson B, Cheverud JM
• CD47 is Required for Mesenchymal Progenitor Proliferation and Fracture Repair.
  Research square 2024 Hankenson K, Zondervan R, Capobianco C, Jenkins D, Reicha J, Frederick L, Lam C, Isenberg J, Ahn J, Marcucio RS
• CD47 is Required for Mesenchymal Progenitor Proliferation and Fracture Repair.
  bioRxiv : the preprint server for biology 2024 Zondervan RL, Capobianco CA, Jenkins DC, Reicha JD, Fredrick LM, Lam C, Isenberg JS, Ahn J, Marcucio RS, Hankenson KD
• Dosage-dependent effects of FGFR2W290R mutation on craniofacial shape and cellular dynamics of the basicranial synchondroses.
  Anatomical record (Hoboken, N.J. : 2007) 2024 Richbourg HA, Vidal-García M, Brakora KA, Devine J, Takenaka R, Young NM, Gong SG, Neves A, Hallgrímsson B, Marcucio RS
• Chapter 5 Macrophages in tissue engineering and regeneration.
  Macrophages Biology and Tissue Inflammation in Health and Disease 2024 Dan Clark, Mary Nakamura, Theodore Miclau, Ralph Marcucio
• Author Correction: MusMorph, a database of standardized mouse morphology data for morphometric meta-analyses.
  Scientific data 2023 Devine J, Vidal-García M, Liu W, Neves A, Lo Vercio LD, Green RM, Richbourg HA, Marchini M, Unger CM, Nickle AC, Radford B, Young NM, Gonzalez PN, Schuler RE, Bugacov A, Rolian C, Percival CJ, …
• The Developmental Basis for Evolvability.
  Evolvability 2023 Benedikt Hallgrímsson, J. David Aponte, Marta Vidal-Garcia, Heather Richbourg, Rebecca Green, Nathan M. Young, James M. Cheverud, Anne L. Calof, Arthur D. Lander, Ralph S. Marcucio
• Encapsulation of β-NGF in injectable microrods for localized delivery accelerates endochondral fracture repair.
  Frontiers in bioengineering and biotechnology 2023 Rivera KO, Cuylear DL, Duke VR, O'Hara KM, Zhong JX, Elghazali NA, Finbloom JA, Kharbikar BN, Kryger AN, Miclau T, Marcucio RS, Bahney CS, Desai TA
• Quantifying the relationship between cell proliferation and morphology during development of the face.
  bioRxiv : the preprint server for biology 2023 Green RM, Lo Vercio LD, Dauter A, Barretto EC, Devine J, Vidal-García M, Marchini M, Robertson S, Zhao X, Mahika A, Shakir MB, Guo S, Boughner JC, Dean W, Lander AD, Marcucio RS, Forkert ND, …
• Altered early immune response after fracture and traumatic brain injury.
  Frontiers in immunology 2023 Haffner-Luntzer M, Weber B, Morioka K, Lackner I, Fischer V, Bahney C, Ignatius A, Kalbitz M, Marcucio R, Miclau T
• Segmentation of Tissues and Proliferating Cells in Light-Sheet Microscopy Images of Mouse Embryos Using Convolutional Neural Networks.
  IEEE access : practical innovations, open solutions 2022 Lo Vercio LD, Green RM, Robertson S, Guo S, Dauter A, Marchini M, Vidal-GARCíA M, Zhao X, Mahika A, Marcucio RS, HALLGRíMSSON B, Forkert ND
• Age-related decrease in periostin expression may be associated with attenuated fracture healing in old mice.
  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2022 Clark D, Doelling J, Hu D, Miclau T, Nakamura M, Marcucio R
• Cardiac alterations following experimental hip fracture - inflammaging as independent risk factor.
  Frontiers in immunology 2022 Lackner I, Weber B, Pressmar J, Odwarka A, Lam C, Haffner-Luntzer M, Marcucio R, Miclau T, Kalbitz M
• Fgf8 dosage regulates jaw shape and symmetry through pharyngeal-cardiac tissue relationships.
  Developmental dynamics : an official publication of the American Association of Anatomists 2022 Zbasnik N, Dolan K, Buczkowski SA, Green RM, Hallgrímsson B, Marcucio RS, Moon AM, Fish JL
• MusMorph, a database of standardized mouse morphology data for morphometric meta-analyses.
  Scientific data 2022 Devine J, Vidal-García M, Liu W, Neves A, Lo Vercio LD, Green RM, Richbourg HA, Marchini M, Unger CM, Nickle AC, Radford B, Young NM, Gonzalez PN, Schuler RE, Bugacov A, Rolian C, Percival CJ, …
• Developmental Morphospace of Embryonic Brain and Face Growth in the Chicken (Gallus gallus).
  The FASEB Journal 2022 Zuzana Vavrušová, Diane Hu, Wei Liu, Ralph S. Marcucio, Benedikt Hallgrímsson, Nathan M. Young
• Downstream Branches of the Fibroblast Growth Factor Signaling Pathway Act Interdependently to Shape the Face.
  The FASEB Journal 2022 Nicholas J. Hanne, Diane Hu, Charlie Allen, Bilal Shakir, Wei Liu, Benedikt Hallgrímsson, Ralph Marcucio
• Relating multivariate shapes to genescapes using phenotype-biological process associations for craniofacial shape.
  eLife 2021 Aponte JD, Katz DC, Roth DM, Vidal-García M, Liu W, Andrade F, Roseman CC, Murray SA, Cheverud J, Graf D, Marcucio RS, Hallgrímsson B
• Extracellular Matrix Composition Is Altered Alongside Dysmorphology in the Developing Palate.
  The FASEB Journal 2021 Nicholas Hanne, Diane Hu, Marta Linde-Medina, Marta Marchini, Benedikt Hallgrímsson, Ralph Marcucio
• Integration of Cellular Dynamics and Morphology to Understand Mouse Facial Development.
  The FASEB Journal 2021 Rebecca Green, Lucas Lo Vercio, Andreas Dauter, Si Han Guo, Samuel Robertson, Marta Marchini, Marta Vidal Garcia, Xiang Zhao, Ralph Marcucio, Nils Forkert, Benedikt Hallgrimsson
• Mapping the Multi-Modal Distribution of Craniofacial Phenotypes in NOSIP Mutants.
  The FASEB Journal 2021 Heather Richbourg, Rebecca Green, Jay Devine, Marta Vidal Garcia, Benedikt Hallgrimsson, Ralph Marcucio
• The Contribution of Macrophages in Old Mice to Periodontal Disease.
  Journal of dental research 2021 Clark D, Halpern B, Miclau T, Nakamura M, Kapila Y, Marcucio R
• Wnt Signaling Drives Correlated Changes in Facial Morphology and Brain Shape.
  Frontiers in cell and developmental biology 2021 Marchini M, Hu D, Lo Vercio L, Young NM, Forkert ND, Hallgrímsson B, Marcucio R
• Systemic and local cardiac inflammation after experimental long bone fracture, traumatic brain injury and combined trauma in mice.
  Journal of orthopaedic translation 2021 Lackner I, Weber B, Haffner-Luntzer M, Hristova S, Gebhard F, Lam C, Morioka K, Marcucio RS, Miclau T, Kalbitz M
• Creating Avian Forebrain Chimeras to assess Facial Development.
  Journal of visualized experiments : JoVE 2021 Hu D, Marcucio RS
• Local injections of β-NGF accelerates endochondral fracture repair by promoting cartilage to bone conversion.
  Scientific reports 2020 Rivera KO, Russo F, Boileau RM, Tomlinson RE, Miclau T, Marcucio RS, Desai TA, Bahney CS
• Chondrocyte-to-osteoblast transformation in mandibular fracture repair.
  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2020 Wong SA, Hu DP, Slocum J, Lam C, Nguyen M, Miclau T, Marcucio RS, Bahney CS
• A novel mouse model to study fracture healing at the proximal femur.
  Bone Reports 2020 Melanie Haffner-Luntzer, Birte Weber, Charles Lam, Verena Fischer, Miriam Kalbitz, Anita Ignatius, Ralph S. Marcucio, Theodore Miclau
• Pak1ip1 Loss-of-Function Leads to Cell Cycle Arrest, Loss of Neural Crest Cells, and Craniofacial Abnormalities.
  Frontiers in cell and developmental biology 2020 Panoutsopoulos AA, De Crescenzo AH, Lee A, Lu AM, Ross AP, Borodinsky LN, Marcucio R, Trainor PA, Zarbalis KS
• miR-199 family contributes to regulation of sonic hedgehog expression during craniofacial development.
  Developmental dynamics : an official publication of the American Association of Anatomists 2020 Richbourg HA, Hu DP, Xu Y, Barczak AJ, Marcucio RS
• A Registration and Deep Learning Approach to Automated Landmark Detection for Geometric Morphometrics.
  Evolutionary biology 2020 Devine J, Aponte JD, Katz DC, Liu W, Lo Vercio LD, Forkert ND, Marcucio R, Percival CJ, Hallgrímsson B
• Blocking Kv1.3 potassium channels prevents postoperative neuroinflammation and cognitive decline without impairing wound healing in mice.
  British journal of anaesthesia 2020 Lai IK, Valdearcos M, Morioka K, Saxena S, Feng X, Li R, Uchida Y, Lijun A, Li W, Pan J, Koliwad S, Marcucio R, Wulff H, Maze M
• Biomedical research models in the science of fracture healing - Pitfalls & promises.
  Injury 2020 Marmor MT, Dailey H, Marcucio R, Hunt AC
• Facial shape and allometry quantitative trait locus intervals in the Diversity Outbred mouse are enriched for known skeletal and facial development genes.
  PloS one 2020 Katz DC, Aponte JD, Liu W, Green RM, Mayeux JM, Pollard KM, Pomp D, Munger SC, Murray SA, Roseman CC, Percival CJ, Cheverud J, Marcucio RS, Hallgrímsson B
• A novel mouse model to study fracture healing of the proximal femur.
  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2020 Haffner-Luntzer M, Weber B, Lam C, Fischer V, Lackner I, Ignatius A, Kalbitz M, Marcucio RS, Miclau T
• Determining the Role of Extracellular Matrix Compliance on Facial Morphogenesis.
  The FASEB Journal 2020 Nicholas Jean Hanne, Diane Hu, Marta Linde-Medina, Benedikt Hallgrimsson, Ralph S. Marcucio
• Late embryonic skull anomalies in mice carrying the Fgfr2 W290R Crouzon mutation.
  The FASEB Journal 2020 M. Kathleen Pitirri, Susan M. Motch Perrine, Risa Takenaka, Ralph Marcucio, Joan Richtsmeier
• Mapping the Multi-Modal Distribution of Craniofacial Phenotypes in NOSIP Mutants.
  The FASEB Journal 2020 Heather A. Richbourg, Alexa Saliou, Jay Devine, Rebecca Green, Meike Hoffmeister, Stefanie Oess, Benedikt Hallgrimsson, Ralph Marcucio
• Mapping the relationship between proliferation and morphology in the developing mouse face.
  The FASEB Journal 2020 Rebecca M. Green, Lucas Lo Vercio, Sihan Guo, Andreas Dauter, Marta Marchini, Xiang Xhao, Ralph S. Marcucio, Benedikt Hallgrimsson
• Regulatory Dynamics of Midfacial Growth in Evolution and Disease.
  The FASEB Journal 2020 Licia Selleri, Ian Welsh, Karissa Hansen, Marco Osterwalder, Marta Losa-Llabata, Julie Wells, Carol Bult, Timothy Mohun, Diane Hu, Ralph Marcucio, Axel Visel, Tomek Swigut
• Age-related changes to macrophages are detrimental to fracture healing in mice.
  Aging cell 2020 Clark D, Brazina S, Yang F, Hu D, Hsieh CL, Niemi EC, Miclau T, Nakamura MC, Marcucio R
• SATB1 establishes ameloblast cell polarity and regulates directional amelogenin secretion for enamel formation.
  BMC biology 2019 Zhang Y, Zheng L, Le M, Nakano Y, Chan B, Huang Y, Torbaty PM, Kohwi Y, Marcucio R, Habelitz S, Den Besten PK, Kohwi-Shigematsu T
• AGE-RELATED CHANGES TO MACROPHAGES AFFECT FRACTURE HEALING.
  Innovation in Aging 2019 Daniel Clark, Theodore Miclau, Mary Nakamura, Ralph Marcucio
• Integration and the Developmental Genetics of Allometry.
  Integrative and comparative biology 2019 Hallgrímsson B, Katz DC, Aponte JD, Larson JR, Devine J, Gonzalez PN, Young NM, Roseman CC, Marcucio RS
• Nonlinear gene expression-phenotype relationships contribute to variation and clefting in the A/WySn mouse.
  Developmental dynamics : an official publication of the American Association of Anatomists 2019 Green RM, Leach CL, Diewert VM, Aponte JD, Schmidt EJ, Cheverud JM, Roseman CC, Young NM, Marcucio RS, Hallgrimsson B
• Differential fracture response to traumatic brain injury suggests dominance of neuroinflammatory response in polytrauma.
  Scientific reports 2019 Morioka K, Marmor Y, Sacramento JA, Lin A, Shao T, Miclau KR, Clark DR, Beattie MS, Marcucio RS, Miclau T, Ferguson AR, Bresnahan JC, Bahney CS
• Fracture repair in the elderly: Clinical and experimental considerations.
  Injury 2019 Meinberg EG, Clark D, Miclau KR, Marcucio R, Miclau T
• Chronic psychosocial stress compromises the immune response and endochondral ossification during bone fracture healing via β-AR signaling.
  Proceedings of the National Academy of Sciences of the United States of America 2019 Haffner-Luntzer M, Foertsch S, Fischer V, Prystaz K, Tschaffon M, Mödinger Y, Bahney CS, Marcucio RS, Miclau T, Ignatius A, Reber SO
• Emergent Properties of Facial Morphogenesis Regulated by Fgf Signaling.
  The FASEB Journal 2019 Ralph Marcucio, Diane Hu, Benedikt Hallgrimsson, Nathan Young
• Integration and the genetics of variation in facial shape.
  The FASEB Journal 2019 Benedikt Hallgrimsson, Jose David Aponte, David C Katz, Jordan J Bannister, Rebecca M Green, Nathan M Young, James M Cheverud, Nils Daniel Forkert, Ralph S Marcucio
• Modeling the Development of Cleft Lip and Palate in Variable Clefting Mouse Strains.
  The FASEB Journal 2019 Rebecca M. Green, Courtney L. Leach, Sihan Guo, Virginia Diewert, Ralph S. Marcucio, Benedikt Hallgrimsson
• The Silent Treatment: miR199 Family Silences Shh during Craniofacial Development.
  The FASEB Journal 2019 Heather Ashley Richbourg, Diane Hu, Ralph Marcucio
• The Society for Craniofacial Genetics and Developmental Biology 41st Annual Meeting.
  American journal of medical genetics. Part A 2019 Taneyhill LA, Moody SA, Cox T, Klein OD, Marcucio R, Schneider RA, Trainor PA
• Cellular biology of fracture healing.
  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2018 Bahney CS, Zondervan RL, Allison P, Theologis A, Ashley JW, Ahn J, Miclau T, Marcucio RS, Hankenson KD
• The developmental-genetics of canalization.
  Seminars in cell & developmental biology 2018 Hallgrimsson B, Green RM, Katz DC, Fish JL, Bernier FP, Roseman CC, Young NM, Cheverud JM, Marcucio RS
• Microenvironmental Regulation of Chondrocyte Plasticity in Endochondral Repair-A New Frontier for Developmental Engineering.
  Frontiers in bioengineering and biotechnology 2018 Wong SA, Rivera KO, Miclau T, Alsberg E, Marcucio RS, Bahney CS
• The Society for Craniofacial Genetics and Developmental Biology 40th annual meeting.
  American journal of medical genetics. Part A 2018 Gammill L, Cox T, Moody S, Taneyhill L, Trainor P, Marcucio R
• Quantifying the Genotype to Phenotype Map in Developing Mice.
  The FASEB Journal 2018 Heather A Richbourg, Nathan Young, Risa Takenaka, Ralph Marcucio
• Understanding the development of variable craniofacial phenotypes caused by altered methylation affecting Wnt9b in A-strain mice.
  The FASEB Journal 2018 Rebecca M. Green, Courtney L. Leach, Eric Schmidt, Virginia Diewert, Ralph S. Marcucio, Benedikt Hallgrimsson
• Untangling Sources of Phenotypic Variation Characterizing the Craniofacial Disease Holoprosencephaly.
  The FASEB Journal 2018 Alexis Lainoff, Nathan Young, Benedikt Hallgrimsson, Ralph Marcucio
• Simulation enabled search for explanatory mechanisms of the fracture healing process.
  PLoS computational biology 2018 Kennedy RC, Marmor M, Marcucio R, Hunt CA
• Living tissues are more than cell clusters: The extracellular matrix as a driving force in morphogenesis.
  Progress in biophysics and molecular biology 2018 Linde-Medina M, Marcucio R
• Developmental constraint through negative pleiotropy in the zygomatic arch.
  EvoDevo 2018 Percival CJ, Green R, Roseman CC, Gatti DM, Morgan JL, Murray SA, Donahue LR, Mayeux JM, Pollard KM, Hua K, Pomp D, Marcucio R, Hallgrímsson B
• Developmental nonlinearity drives phenotypic robustness.
  Nature communications 2017 Green RM, Fish JL, Young NM, Smith FJ, Roberts B, Dolan K, Choi I, Leach CL, Gordon P, Cheverud JM, Roseman CC, Williams TJ, Marcucio RS, Hallgrímsson B
• Effects of Aging on Fracture Healing.
  Current osteoporosis reports 2017 Clark D, Nakamura M, Miclau T, Marcucio R
• Reverse engineering development: Crosstalk opportunities between developmental biology and tissue engineering.
  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2017 Marcucio RS, Qin L, Alsberg E, Boerckel JD
• Stimulating Fracture Healing in Ischemic Environments: Does Oxygen Direct Stem Cell Fate during Fracture Healing?
  Frontiers in cell and developmental biology 2017 Miclau KR, Brazina SA, Bahney CS, Hankenson KD, Hunt TK, Marcucio RS, Miclau T
• Fgf8 dosage and tissue interactions contribute to jaw asymmetry in disease.
  The FASEB Journal 2017 Jennifer L. Fish, Katie Dolan, Rebecca Green, Ralph S Marcucio, Benedikt Hallgrimsson
• QTL Analysis of a Trade-off in Bone Length within the Mouse Zygomatic Arch.
  The FASEB Journal 2017 Christopher J. Percival, Rebecca Green, Daniel M. Gatti, Daniel Pomp, Charles C. Roseman, Ralph Marcucio, Benedikt Hallgrímsson
• Shaping the sound of voice.
  eLife 2017 Marcucio R
• Craniofacial diversification in the domestic pigeon and the evolution of the avian skull.
  Nature ecology & evolution 2017 Young NM, Linde-Medina M, Fondon JW, Hallgrímsson B, Marcucio RS
• Quantifying three-dimensional morphology and RNA from individual embryos.
  Developmental dynamics : an official publication of the American Association of Anatomists 2017 Green RM, Leach CL, Hoehn N, Marcucio RS, Hallgrímsson B
• The society for craniofacial genetics and developmental biology 39th annual meeting.
  American journal of medical genetics. Part A 2017 Fish JL, Albertson C, Harris MP, Lozanoff S, Marcucio RS, Richtsmeier JT, Trainor PA
• Development Shapes a Consistent Inbreeding Effect in Mouse Crania of Different Line Crosses.
  Journal of experimental zoology. Part B, Molecular and developmental evolution 2017 Pavlicev M, Mitteroecker P, Gonzalez PM, Rolian C, Jamniczky H, Villena FP, Marcucio R, Spritz R, Hallgrimsson B
• Future Treatment Strategies for Delayed Bone Healing: An Osteoimmunologic Approach.
  The Journal of the American Academy of Orthopaedic Surgeons 2016 Schmidt-Bleek K, Marcucio R, Duda G
• FGFR-associated craniosynostosis syndromes and gastrointestinal defects.
  American journal of medical genetics. Part A 2016 Hibberd CE, Bowdin S, Arudchelvan Y, Forrest CR, Brakora KA, Marcucio RS, Gong SG
• Genetic structure of phenotypic robustness in the collaborative cross mouse diallel panel.
  Journal of evolutionary biology 2016 Gonzalez PN, Pavlicev M, Mitteroecker P, Pardo-Manuel de Villena F, Spritz RA, Marcucio RS, Hallgrímsson B
• The society for craniofacial genetics and developmental biology 38th annual meeting.
  American journal of medical genetics. Part A 2016 Taneyhill LA, Hoover-Fong J, Lozanoff S, Marcucio R, Richtsmeier JT, Trainor PA
• 60 Minutes of Tension: The Hour Long Research Talk.
  The FASEB Journal 2016 Ralph Marcucio
• Evolvability and the Diversification of the Craniofacial Skeleton in the Domesticated Pigeon ( Columba livia ).
  The FASEB Journal 2016 Marta Linde-Medina, John Fondon, Ralph Marcucio, Benedikt Hallgrímsson, Nathan M. Young
• Facial surface morphology predicts variation in internal skeletal shape.
  American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 2016 Young NM, Sherathiya K, Gutierrez L, Nguyen E, Bekmezian S, Huang JC, Hallgrímsson B, Lee JS, Marcucio RS
• Factors affecting craniofacial development in a mouse model of Crouzon Syndrome.
  The FASEB Journal 2016 Katherine Brakora, Christopher J Percival, Rebecca Green, Siew-Ging Gong, Benedikt Hallgrimsson, Ralph Marcucio
• Matrix Reloaded: Devitalized Cartilage as a Functional Extracellular Niche to Promote Osteogenesis and Angiogenesis.
  The FASEB Journal 2016 Jaselle M Perry, Donna M Poscablo, Brandon T Gaston, Diane P Hu, Theodore Miclau, Karen L Christman, Ralph S Marcucio, Chelsea S Bahney
• Trans differentiation of Chondrocytes to Osteoblasts during Endochondral Ossification in the Healing Mandible.
  The FASEB Journal 2016 Sarah Anne Wong, Diane Hu, Theodore Miclau, Chelsea Bahney, Ralph Marcucio
• Transdifferentiation of Chondrocytes to Osteoblasts during Bone Fracture Healing.
  The FASEB Journal 2016 Ralph Marcucio, Diane Hu, Frank Yang, Chelsea Bahney, Theodore Miclau
• Promoting Endochondral Bone Repair Using Human Osteoarthritic Articular Chondrocytes.
  Tissue engineering. Part A 2016 Bahney CS, Jacobs L, Tamai R, Hu D, Luan TF, Wang M, Reddy S, Park M, Limburg S, Kim HT, Marcucio R, Kuo AC
• Beyond cell proliferation in avian facial morphogenesis.
  Developmental dynamics : an official publication of the American Association of Anatomists 2016 Linde-Medina M, Hallgrímsson B, Marcucio R
• Stem Cell Therapies in Orthopaedic Trauma.
  Journal of orthopaedic trauma 2015 Marcucio RS, Nauth A, Giannoudis PV, Bahney C, Piuzzi NS, Muschler G, Miclau T
• Tissue engineering strategies for promoting vascularized bone regeneration.
  Bone 2015 Almubarak S, Nethercott H, Freeberg M, Beaudon C, Jha A, Jackson W, Marcucio R, Miclau T, Healy K, Bahney C
• Morphometrics, 3D Imaging, and Craniofacial Development.
  Current topics in developmental biology 2015 Hallgrimsson B, Percival CJ, Green R, Young NM, Mio W, Marcucio R
• Genetics of murine craniofacial morphology: diallel analysis of the eight founders of the Collaborative Cross.
  Journal of anatomy 2015 Percival CJ, Liberton DK, Pardo-Manuel de Villena F, Spritz R, Marcucio R, Hallgrímsson B
• Correlations Between the Morphology of Sonic Hedgehog Expression Domains and Embryonic Craniofacial Shape.
  Evolutionary biology 2015 Xu Q, Jamniczky H, Hu D, Green RM, Marcucio RS, Hallgrimsson B, Mio W
• Signals from the brain induce variation in avian facial shape.
  Developmental dynamics : an official publication of the American Association of Anatomists 2015 Hu D, Young NM, Xu Q, Jamniczky H, Green RM, Mio W, Marcucio RS, Hallgrimsson B
• Divergence of craniofacial developmental trajectories among avian embryos.
  Developmental dynamics : an official publication of the American Association of Anatomists 2015 Smith FJ, Percival CJ, Young NM, Hu D, Schneider RA, Marcucio RS, Hallgrimsson B
• Role of muscle stem cells during skeletal regeneration.
  Stem cells (Dayton, Ohio) 2015 Abou-Khalil R, Yang F, Lieu S, Julien A, Perry J, Pereira C, Relaix F, Miclau T, Marcucio R, Colnot C
• Facial development and alterations in FGF signaling in a mouse model of Crouzon Syndrome.
  The FASEB Journal 2015 Katherine Brakora, Yolanda Ho, Alexis Lainoff, Jennifer Wong, Siew-Ging Gong, Benedikt Hallgrimsson, Ralph Marcucio
• Mechanisms of FGF-Mediated Morphogenesis.
  The FASEB Journal 2015 Ralph Marcucio
• The synergistic effect of micro-topography and biochemical culture environment to promote angiogenesis and osteogenic differentiation of human mesenchymal stem cells.
  Acta biomaterialia 2015 Song S, Kim EJ, Bahney CS, Miclau T, Marcucio R, Roy S
• A comparative examination of odontogenic gene expression in both toothed and toothless amniotes.
  Journal of experimental zoology. Part B, Molecular and developmental evolution 2015 Lainoff AJ, Moustakas-Verho JE, Hu D, Kallonen A, Marcucio RS, Hlusko LJ
• The multifaceted role of the vasculature in endochondral fracture repair.
  Frontiers in endocrinology 2015 Bahney CS, Hu DP, Miclau T, Marcucio RS
• A dynamic Shh expression pattern, regulated by SHH and BMP signaling, coordinates fusion of primordia in the amniote face.
  Development (Cambridge, England) 2015 Hu D, Young NM, Li X, Xu Y, Hallgrímsson B, Marcucio RS
• Content Experts.
  Larsen's Human Embryology 2015 Richard Anderson, Parker B. Antin, Cammon Arrington, Spencer Beasley, Brian L. Black, Janice L.B. Byrne, Jon Clarke, Martyn Cobourne, Simon J. Conway, Andrew Copp, George P. Daston, Mark Davenport, …
• Impact of retinoic acid exposure on midfacial shape variation and manifestation of holoprosencephaly in Twsg1 mutant mice.
  Disease models & mechanisms 2014 Billington CJ, Schmidt B, Marcucio RS, Hallgrimsson B, Gopalakrishnan R, Petryk A
• Tfap2a-dependent changes in mouse facial morphology result in clefting that can be ameliorated by a reduction in Fgf8 gene dosage.
  Disease models & mechanisms 2014 Green RM, Feng W, Phang T, Fish JL, Li H, Spritz RA, Marcucio RS, Hooper J, Jamniczky H, Hallgrímsson B, Williams T
• Let's face it--complex traits are just not that simple.
  PLoS genetics 2014 Hallgrimsson B, Mio W, Marcucio RS, Spritz R
• Holoprosencephaly: signaling interactions between the brain and the face, the environment and the genes, and the phenotypic variability in animal models and humans.
  Wiley interdisciplinary reviews. Developmental biology 2014 Petryk A, Graf D, Marcucio R
• Surface landmark quantification of embryonic mouse craniofacial morphogenesis.
  BMC developmental biology 2014 Percival CJ, Green R, Marcucio R, Hallgrímsson B
• Biological perspectives of delayed fracture healing.
  Injury 2014 Hankenson KD, Zimmerman G, Marcucio R
• A comparative examination of odontogenic markers in both toothed and toothless amniotes (344.3).
  The FASEB Journal 2014 Alexis Lainoff, Jacqueline Moustakas, Aki Kallonen, Keijo Hämälainen, Kathleen Smith, Diane Hu, Ralph Marcucio, Leslea Hlusko
• Endochondral bone tissue engineering: using cartilage to drive vascularized bone regeneration (87.6).
  The FASEB Journal 2014 Chelsea Bahney, Amit Jha, Diane Hu, Aaron Taylor, Hayley Britz, Benedikt Hallgrimsson, Ted Miclau, Ralph Marcucio
• Therapeutic delivery of placental stem cells to modulate vasculature and promote fracture repair (342.6).
  The FASEB Journal 2014 Chelsea Bahney, Aaron Taylor, Ali Sadat, Kathryn Tormos, Ted Miclau, Emin Maltepe, Ralph Marcucio
• Transdifferentiation of hypertrophic chondrocytes during endochondral bone repair by activation of pluripotent stem cell programs (216.1).
  The FASEB Journal 2014 Chelsea Bahney, Diane Hu, Federico Ferro, Aaron Taylor, Ted Miclau, Ralph Marcucio
• Embryonic bauplans and the developmental origins of facial diversity and constraint.
  Development (Cambridge, England) 2014 Young NM, Hu D, Lainoff AJ, Smith FJ, Diaz R, Tucker AS, Trainor PA, Schneider RA, Hallgrímsson B, Marcucio RS
• Delayed bone regeneration is linked to chronic inflammation in murine muscular dystrophy.
  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2014 Abou-Khalil R, Yang F, Mortreux M, Lieu S, Yu YY, Wurmser M, Pereira C, Relaix F, Miclau T, Marcucio RS, Colnot C
• 9 Cartilage grafts for bone repair and regeneration.
  Bone Substitute Biomaterials 2014 C.S. Bahney, R.S. Marcucio
• Contributor contact details.
  Bone Substitute Biomaterials 2014 K.K. Mallick, S. Sprio, M. Sandri, M. Iafisco, A. Ruffini, S. Minardi, A. Tampieri, P. Bhattacharya, G.H. van Lenthe, E.B. Hunziker, T.J. Blokhuis, V. Guarino, M.G. Raucci, A. Ronca, V. Cirillo, L. …
• Modulation of macrophage activity during fracture repair has differential effects in young adult and elderly mice.
  Journal of orthopaedic trauma 2014 Slade Shantz JA, Yu YY, Andres W, Miclau T, Marcucio R
• Selective estrogen receptor modulation prevents scoliotic curve progression: radiologic and histomorphometric study on a bipedal C57Bl6 mice model.
  European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society 2013 Demirkiran G, Dede O, Yalcin N, Akel I, Marcucio R, Acaroglu E
• Quantification of shape and cell polarity reveals a novel mechanism underlying malformations resulting from related FGF mutations during facial morphogenesis.
  Human molecular genetics 2013 Li X, Young NM, Tropp S, Hu D, Xu Y, Hallgrímsson B, Marcucio RS
• Beneficial effects of oxygen- and lactate-production in scaffold designs.
  Bone 2013 Marcucio R, Hunt TK, Miclau T
• The effect of hypoxia on facial shape variation and disease phenotypes in chicken embryos.
  Disease models & mechanisms 2013 Smith F, Hu D, Young NM, Lainoff AJ, Jamniczky HA, Maltepe E, Hallgrimsson B, Marcucio RS
• Embryonic origins of novelty and constraint in the amniote upper jaw.
  The FASEB Journal 2013 Nathan Young, Diane Hu, Alexis Lainoff, Benedikt Hallgrímsson, Ralph Marcucio
• Disruption of thrombospondin-2 accelerates ischemic fracture healing.
  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2012 Miedel E, Dishowitz MI, Myers MH, Dopkin D, Yu YY, Miclau TS, Marcucio R, Ahn J, Hankenson KD
• Fgf8 dosage determines midfacial integration and polarity within the nasal and optic capsules.
  Developmental biology 2012 Griffin JN, Compagnucci C, Hu D, Fish J, Klein O, Marcucio R, Depew MJ
• MMP9 regulates the cellular response to inflammation after skeletal injury.
  Bone 2012 Wang X, Yu YY, Lieu S, Yang F, Lang J, Lu C, Werb Z, Hu D, Miclau T, Marcucio R, Colnot C
• The generation of variation and the developmental basis for evolutionary novelty.
  Journal of experimental zoology. Part B, Molecular and developmental evolution 2012 Hallgrímsson B, Jamniczky HA, Young NM, Rolian C, Schmidt-Ott U, Marcucio RS
• Anti-inflammatory treatment increases angiogenesis during early fracture healing.
  Archives of orthopaedic and trauma surgery 2012 Lu C, Xing Z, Wang X, Mao J, Marcucio RS, Miclau T
• Creating Rigidly Stabilized Fractures for Assessing Intramembranous Ossification, Distraction Osteogenesis, or Healing of Critical Sized Defects.
  Journal of Visualized Experiments 2012 Yan-yiu Yu, Chelsea Bahney, Diane Hu, Ralph S. Marcucio, Theodore Miclau, III
• Creating rigidly stabilized fractures for assessing intramembranous ossification, distraction osteogenesis, or healing of critical sized defects.
  Journal of visualized experiments : JoVE 2012 Yu YY, Bahney C, Hu D, Marcucio RS, Miclau T
• A Novel Gene Crispld2 may Contribute to Facial Dysmophology in a Chicken Model of Crouzon's Syndrome.
  The FASEB Journal 2012 Xin Li, Stephen Tropp, Nathan Young, Benedikt Hallgrimsson, Ralph Marcucio
• Modulation of Shh signaling by microRNAs.
  The FASEB Journal 2012 Yanhua Xu, Diane Hu, Rebecca Barbeau, Andrea Barczak, Ralph Marcucio
• Neural crest cells pattern the surface cephalic ectoderm during FEZ formation.
  Developmental dynamics : an official publication of the American Association of Anatomists 2012 Hu D, Marcucio RS
• The Phenogenomics of Craniofacial Shape.
  The FASEB Journal 2012 Benedikt Hallgrimsson, Heather A. Jamniczky, Neus Martínez-Abadías, Nathan M. Young, Ralph S. Marcucio
• Tissue Interactions that Regulate Facial Morphogenesis.
  The FASEB Journal 2012 Ralph Marcucio, Nathan Young, Diane Hu, Benedikt Hallgrimsson
• Tissue engineering bone by recapitulating developmental and repair programs offers improved biological outcomes.
  The FASEB Journal 2012 Chelsea Shields Bahney, Diane Hu, Theodore Miclau, Ralph Marcucio
• The metabolic basis of adolescent idiopathic scoliosis: 2011 report of the "metabolic" workgroup of the Fondation Yves Cotrel.
  European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society 2012 Acaroglu E, Bobe R, Enouf J, Marcucio R, Moldovan F, Moreau A
• Signaling by SHH rescues facial defects following blockade in the brain.
  Developmental dynamics : an official publication of the American Association of Anatomists 2012 Chong HJ, Young NM, Hu D, Jeong J, McMahon AP, Hallgrimsson B, Marcucio RS
• Vascular endothelial growth factor improves bone repair in a murine nonunion model.
  The Iowa orthopaedic journal 2012 Ogilvie CM, Lu C, Marcucio R, Lee M, Thompson Z, Hu D, Helms JA, Miclau T
• Epigenetic integration of the developing brain and face.
  Developmental Dynamics 2011 Trish E. Parsons, Eric J. Schmidt, Julia C. Boughner, Heather A. Jamniczky, Ralph S. Marcucio, Benedikt Hallgrímsson
• Is decreased bone mineral density associated with development of scoliosis? A bipedal osteopenic rat model.
  Scoliosis 2011 Dede O, Akel I, Demirkiran G, Yalcin N, Marcucio R, Acaroglu E
• Epigenetic integration of the developing brain and face.
  Developmental dynamics : an official publication of the American Association of Anatomists 2011 Parsons TE, Schmidt EJ, Boughner JC, Jamniczky HA, Marcucio RS, Hallgrímsson B
• Mechanical stability affects angiogenesis during early fracture healing.
  Journal of orthopaedic trauma 2011 Lu C, Saless N, Hu D, Wang X, Xing Z, Hou H, Williams B, Swartz HM, Colnot C, Miclau T, Marcucio RS
• Structured three-dimensional co-culture of mesenchymal stem cells with chondrocytes promotes chondrogenic differentiation without hypertrophy.
  Osteoarthritis and cartilage 2011 Cooke ME, Allon AA, Cheng T, Kuo AC, Kim HT, Vail TP, Marcucio RS, Schneider RA, Lotz JC, Alliston T
• Effects of Bone Morphogenetic Proteins on TGF-beta, Wnt and BMP Pathways During Tibial Fracture Repair.
  The FASEB Journal 2011 Yan Yiu Yu, Shirley Lieu, Theodore Miclau, Celine Colnot, Ralph Marcucio
• Identification and Validation of Gene Expression Profile in Facial Dysmorphology of Craniosynostosis Crouzon Syndrome.
  The FASEB Journal 2011 Xin Li, Stephen Tropp, Niousha Saghafi, Ralph Marcucio
• The cellular basis of hypoxia induced craniofacial malformations.
  The FASEB Journal 2011 Francis Joel Smith, Ralph S Marcucio, Diane Hu, Benedikt Hallgrimsson
• Assessing Signaling Properties of Ectodermal Epithelia During Craniofacial Development.
  Journal of Visualized Experiments 2011 Diane Hu, Ralph S. Marcucio
• Assessing signaling properties of ectodermal epithelia during craniofacial development.
  Journal of visualized experiments : JoVE 2011 Hu D, Marcucio RS
• Mechanisms that underlie co-variation of the brain and face.
  Genesis (New York, N.Y. : 2000) 2011 Marcucio RS, Young NM, Hu D, Hallgrimsson B
• Impaired remodeling phase of fracture repair in the absence of matrix metalloproteinase-2.
  Disease models & mechanisms 2010 Lieu S, Hansen E, Dedini R, Behonick D, Werb Z, Miclau T, Marcucio R, Colnot C
• Quantitative analyses link modulation of sonic hedgehog signaling to continuous variation in facial growth and shape.
  Development (Cambridge, England) 2010 Young NM, Chong HJ, Hu D, Hallgrímsson B, Marcucio RS
• Trauma-induced inflammation and fracture healing.
  Journal of orthopaedic trauma 2010 Pape HC, Marcucio R, Humphrey C, Colnot C, Knobe M, Harvey EJ
• Rejuvenation of the inflammatory system stimulates fracture repair in aged mice.
  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2010 Xing Z, Lu C, Hu D, Miclau T, Marcucio RS
• Action of IL-1beta during fracture healing.
  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2010 Lange J, Sapozhnikova A, Lu C, Hu D, Li X, Miclau T, Marcucio RS
• Recombinant human bone morphogenetic protein-7 enhances fracture healing in an ischemic environment.
  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2010 Lu C, Xing Z, Yu YY, Colnot C, Miclau T, Marcucio RS
• A craniosynostosis-syndrome related Fgfr2 mutation promotes early craniofacial defects in chick.
  The FASEB Journal 2010 Xin Li, Stephen Tropp, Ralph Marcucio
• Multiple roles for CCR2 during fracture healing.
  Disease models & mechanisms 2010 Xing Z, Lu C, Hu D, Yu YY, Wang X, Colnot C, Nakamura M, Wu Y, Miclau T, Marcucio RS
• Absence of beta3 integrin accelerates early skeletal repair.
  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2010 Hu D, Lu C, Sapozhnikova A, Barnett M, Sparrey C, Miclau T, Marcucio RS
• Deciphering the Palimpsest: Studying the Relationship Between Morphological Integration and Phenotypic Covariation.
  Evolutionary biology 2009 Hallgrímsson B, Jamniczky H, Young NM, Rolian C, Parsons TE, Boughner JC, Marcucio RS
• Immunolocalization of BMPs, BMP antagonists, receptors, and effectors during fracture repair.
  Bone 2009 Yu YY, Lieu S, Lu C, Miclau T, Marcucio RS, Colnot C
• Basic research in orthopedic surgery: Current trends and future directions.
  Indian journal of orthopaedics 2009 Lu C, Buckley JM, Colnot C, Marcucio R, Miclau T
• Comparison of the melatonin and calmodulin in paravertebral muscle and platelets of patients with or without adolescent idiopathic scoliosis.
  Spine 2009 Acaroglu E, Akel I, Alanay A, Yazici M, Marcucio R
• Hypoxia as an Environmental Cause of Holoprosencephaly.
  The FASEB Journal 2009 Francis Joel Smith, Ralph S Marcucio
• Rescuing craniofacial development in an avian model of holoprosencephaly.
  The FASEB Journal 2009 H. Jonathan Chong, Ralph Marcucio
• The effect of early Bone Morphogenetic Protein (BMP) activation on craniofacial development.
  The FASEB Journal 2009 H. Jonathan Chong, Ralph Marcucio
• The relationship between variable SHH signaling and the severity of structural defects in the face and brain.
  The FASEB Journal 2009 Nathan M. Young, Diane Hu, H. Jonathan Chong, Benedikt Hallgrímsson, Wei Liu, Ralph Marcucio
• The effect of calmodulin antagonists on experimental scoliosis: a pinealectomized chicken model.
  Spine 2009 Akel I, Kocak O, Bozkurt G, Alanay A, Marcucio R, Acaroglu E
• The effect of calmodulin antagonists on scoliosis: bipedal C57BL/6 mice model.
  European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society 2009 Akel I, Demirkiran G, Alanay A, Karahan S, Marcucio R, Acaroglu E
• Effect of bone morphogenetic protein signaling on development of the jaw skeleton.
  Developmental dynamics : an official publication of the American Association of Anatomists 2008 Hu D, Colnot C, Marcucio RS
• A SHH-responsive signaling center in the forebrain regulates craniofacial morphogenesis via the facial ectoderm.
  Development (Cambridge, England) 2008 Hu D, Marcucio RS
• Unique organization of the frontonasal ectodermal zone in birds and mammals.
  Developmental biology 2008 Hu D, Marcucio RS
• Effect of age on vascularization during fracture repair.
  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2008 Lu C, Hansen E, Sapozhnikova A, Hu D, Miclau T, Marcucio RS
• Epithelial-Mesenchymal Interactions during Facial Development in Mice.
  The FASEB Journal 2008 Ralph Marcucio, Diane Hu
• Tibial fracture decreases oxygen levels at the site of injury.
  The Iowa orthopaedic journal 2008 Lu C, Rollins M, Hou H, Swartz HM, Hopf H, Miclau T, Marcucio RS
• Effects of delayed stabilization on fracture healing.
  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2007 Miclau T, Lu C, Thompson Z, Choi P, Puttlitz C, Marcucio R, Helms JA
• Role of matrix metalloproteinase 13 in both endochondral and intramembranous ossification during skeletal regeneration.
  PloS one 2007 Behonick DJ, Xing Z, Lieu S, Buckley JM, Lotz JC, Marcucio RS, Werb Z, Miclau T, Colnot C
• Signaling by bone morphogenetic proteins directs formation of an ectodermal signaling center that regulates craniofacial development.
  Developmental biology 2007 Foppiano S, Hu D, Marcucio RS
• Bone morphogenetic proteins (BMPs) direct formation of a signaling center that regulates facial development.
  Developmental Biology 2007 Ralph S. Marcucio, Silvia Foppiano, Diane Hu
• Ischemia leads to delayed union during fracture healing: a mouse model.
  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2007 Lu C, Miclau T, Hu D, Marcucio RS
• Patterns of infantile hemangiomas: new clues to hemangioma pathogenesis and embryonic facial development.
  Pediatrics 2006 Haggstrom AN, Lammer EJ, Schneider RA, Marcucio R, Frieden IJ
• Assessing angiogenesis during fracture healing.
  The Iowa orthopaedic journal 2006 Lu C, Marcucio R, Miclau T
• Cellular basis for age-related changes in fracture repair.
  Journal of Orthopaedic Research® 2005 C LU, T MICLAU, D HU, E HANSEN, K TSUI, C PUTTLITZ, R MARCUCIO
• Molecular interactions coordinating the development of the forebrain and face.
  Developmental biology 2005 Marcucio RS, Cordero DR, Hu D, Helms JA
• Cellular basis for age-related changes in fracture repair.
  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2005 Lu C, Miclau T, Hu D, Hansen E, Tsui K, Puttlitz C, Marcucio RS
• The Collaborative Cross, a community resource for the genetic analysis of complex traits.
  Nature genetics 2004 Churchill GA, Airey DC, Allayee H, Angel JM, Attie AD, Beatty J, Beavis WD, Belknap JK, Bennett B, Berrettini W, Bleich A, Bogue M, Broman KW, Buck KJ, Buckler E, Burmeister M, Chesler EJ, Cheverud JM…
• Temporal perturbations in sonic hedgehog signaling elicit the spectrum of holoprosencephaly phenotypes.
  The Journal of clinical investigation 2004 Cordero D, Marcucio R, Hu D, Gaffield W, Tapadia M, Helms JA
• Morphogenesis of blood vessels in the head muscles of avian embryo: spatial, temporal, and VEGF expression analyses.
  Developmental dynamics : an official publication of the American Association of Anatomists 2003 Ruberte J, Carretero A, Navarro M, Marcucio RS, Noden D
• A zone of frontonasal ectoderm regulates patterning and growth in the face.
  Development (Cambridge, England) 2003 Hu D, Marcucio RS, Helms JA
• Prenatal morphogenesis of the human mental foramen.
  European journal of oral sciences 2002 Radlanski RJ, Renz H, Müller U, Schneider RS, Marcucio RS, Helms JA
• Differentiation of avian craniofacial muscles: I. Patterns of early regulatory gene expression and myosin heavy chain synthesis.
  Developmental dynamics : an official publication of the American Association of Anatomists 1999 Noden DM, Marcucio R, Borycki AG, Emerson CP
• Myotube heterogeneity in developing chick craniofacial skeletal muscles.
  Developmental dynamics : an official publication of the American Association of Anatomists 1999 Marcucio RS, Noden DM
• In vitro interaction between oviduct epithelial and equine sperm.
  Archives of andrology 1993 Ellington JE, Ignotz GG, Varner DD, Marcucio RS, Mathison P, Ball BA