Radhika Mathur, PhD
Assistant Researcher
Neurological Surgery
School of Medicine
Awards
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- Ruth L. Kirschstein National Research Service Award (F31), National Institutes of Health (NIH), National Cancer Institute (NCI), 2015-2017
- Andrew Parsa Young Investigator Award for Basic/Translational Research, Society for Neuro-Oncology (SNO), 2020
- Best Poster Award, Annual Postdoc and Graduate Student Retreat, Dana-Farber Cancer Institute, 2015
- Best Poster Award, Spring Symposium, Harvard Program In Therapeutics Science, 2015
- Distinction in General Scholarship, UC Berkeley, 2012
- High Honors, Economics, UC Berkeley, 2012
- Honors, Molecular and Cell Biology, UC Berkeley, 2012
Education & Training
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- Ph.D. Biological and Biomedical Sciences Harvard University 05/2017
- Internship Science Policy White House Office Of Science and Technology Policy 12/2016
- BA Molecular and Cell Biology, Economics University of California, Berkeley 05/2012
Grants and Projects
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Publications (16)
Top publication keywords:
DNA Modification MethylasesBrain NeoplasmsEnhancer Elements, GeneticChromatin Assembly and DisassemblyModels, BiologicalTranscription FactorsTumor Suppressor ProteinsNuclear ProteinsDNA Repair EnzymesGenetic HeterogeneityColonic NeoplasmsEpigenomicsTelomeraseGlioblastomaGlioma
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Glioblastoma evolution and heterogeneity from a 3D whole-tumor perspective.
Cell 2024 Mathur R, Wang Q, Schupp PG, Nikolic A, Hilz S, Hong C, Grishanina NR, Kwok D, Stevers NO, Jin Q, Youngblood MW, Stasiak LA, Hou Y, Wang J, Yamaguchi TN, Lafontaine M, Shai A, Smirnov IV, Solomon DA, … -
MGMT promoter methylation level in newly diagnosed low-grade glioma is a predictor of hypermutation at recurrence.
Neuro-oncology 2020 Mathur R, Zhang Y, Grimmer MR, Hong C, Zhang M, Bollam S, Petrecca K, Clarke J, Berger MS, Phillips JJ, Oberheim-Bush NA, Molinaro AM, Chang SM, Costello JF -
ARID1A loss in cancer: Towards a mechanistic understanding.
Pharmacology & therapeutics 2018 Mathur R -
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice.
Nature genetics 2016 Mathur R, Alver BH, San Roman AK, Wilson BG, Wang X, Agoston AT, Park PJ, Shivdasani RA, Roberts CW -
Whole tumor analysis reveals early origin of the TERT promoter mutation and intercellular heterogeneity in TERT expression.
Neuro-oncology 2024 Appin CL, Hong C, Suwala AK, Hilz S, Mathur R, Solomon DA, Smirnov IV, Stevers NO, Shai A, Wang A, Berger MS, Chang SM, Phillips JJ, Costello JF
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GABP couples oncogene signaling to telomere regulation in TERT promoter mutant cancer.
Cell reports 2022 McKinney AM, Mathur R, Stevers NO, Molinaro AM, Chang SM, Phillips JJ, Costello JF -
Abstract 3621: 3D spatial sampling and integrated omics reveal sources and patterning of intratumoral heterogeneity in glioblastoma.
Cancer Research 2022 Radhika Mathur, Qixuan Wang, Patrick Schupp, Ana Nikolic, Takafumi Yamaguchi, Stephanie Hilz, Chibo Hong, Ivan Smirnov, Marisa LaFontaine, Joanna Phillips, Susan Chang, Yan Li, Janine Lupo, Paul … -
Abstract 3797: 3D whole tumor analysis of the TERT promoter mutation in gliomas.
Cancer Research 2022 Christina Leann Appin, Abigail K. Suwala, Stephanie Hilz, Radhika Mathur, Ivan V. Smirnov, Chibo Hong, Nicholas O. Stevers, Anny Shai, Albert Wang, Mitchel S. Berger, Susan M. Chang, Joanna J. … -
PATH-28. RE-DEFINING CLONALITY OF THE TERT PROMOTER MUTATION WITH DEEP SEQUENCING AND MAXIMAL SAMPLING OF NEWLY DIAGNOSED AND RECURRENT GBM AND OLIGODENDROGLIOMA.
Neuro-Oncology 2021 Christina Appin, Abigail K Suwala, Stephanie Hilz, Radhika Mathur, Ivan Smirnov, Chibo Hong, Nicholas Stevers, Anny Shai, Mitchel Berger, Susan Chang, Joanna Phillips, Joseph Costello -
Epigenomic contributions to tumor cell heterogeneity and plasticity.
Nature genetics 2021 Mathur R, Costello JF -
ECOA-5. Integrative 3D spatial characterization of genomic and epigenomic intratumoral heterogeneity in glioblastoma.
Neuro-Oncology Advances 2021 Radhika Mathur, Qixuan Wang, Patrick Schupp, Stephanie Hilz, Chibo Hong, Ivan Smirnov, Marisa Lafontaine, Devika Nair, Sriranga Iyyanaki, Joanna Phillips, Susan Chang, Yan Li, Janine Lupo, Michael … -
EPCO-31. EPIGENOMIC INTRATUMORAL HETEROGENEITY OF GLIOBLASTOMA IN THREE-DIMENSIONAL SPACE.
Neuro-Oncology 2020 Radhika Mathur, Sriranga Iyyanki, Stephanie Hilz, Chibo Hong, Joanna Phillips, Susan Chang, Feng Yue, Joseph Costello -
GENE-35. MGMT PROMOTER METHYLATION IN NEWLY DIAGNOSED LGG AS A POTENTIAL BIOMARKER FOR TMZ-ASSOCIATED HYPERMUTATION AT RECURRENCE.
Neuro-Oncology 2019 Radhika Mathur, Yalan Zhang, Matthew Grimmer, Chibo Hong, Mitchel Berger, Annette Molinaro, Nancy Ann Oberheim-Bush, Susan Chang, Joseph Costello -
SWI/SNF (BAF) Complexes: Guardians of the Epigenome.
Annual Review of Cancer Biology 2018 Radhika Mathur, Charles W.M. Roberts -
SWI/SNF (BAF) Complexes: Guardians of the Epigenome
Annual Review of Cancer Biology 2017 Radhika Mathur, Charles W. M. Roberts -
Abstract LB-286: ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice.
Molecular and Cellular Biology, Genetics 2017 Radhika Mathur, Burak H. Alver, Adrianna K. San Roman, Boris G. Wilson, Xiaofeng Wang, Agoston T. Agoston, Peter Park, Ramesh Shivdasani, Charles W. Roberts