Prasad Shirvalkar, MD, PhD
Associate Professor
Anesthesia
School of Medicine
Awards
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- LRP, National Institutes of Health, 2019-2021
- Catalyst Innovation Award, UCSF, 2019-2020
- Best Scientific Abstract, International Neuromodulation Society, 2019
- Exceptional Clinician Award - Hon Mention, UCSF, 2018
- Outstanding Neurology Teaching Award, Weill Cornell Medicine, 2016
Education & Training
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- Fellowship Pain Management University of California San Francisco 2017
- Residency Neurology Weill Cornell Medical College / Memorial Sloan Kettering Cancer Center 2016
- MD PhD PhD - Neuroscience Icahn School of Medicine at Mount Sinai 2012
- Postdoctoral Neuroscience Rockefeller University 2012
Interests
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- Deep Brain Stimulation
- Neuropathic Pain
- Spinal Cord Stimulation
- Post Stroke Pain
- Neuromodulation
- Phantom Limb Pain
- Pain Management
- Headache
Grants and Projects
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- Precision Medicine for Chronic Pain: Personalized Brain Network Modulation for Chronic Neuropathic Pain Syndromes, George and Judy Marcus Innovation Fund, 2023-2025
- Multisite adaptive brain stimulation for multidimensional treatment of refractory chronic pain, NIH, 2019-2024
- Technology development for closed-loop deep brain stimulation to treat refractory neuropathic pain, NIH, 2019-2024
- Improving Access to Pain Psychology Services for Medicaid Patients, Mount Zion Health Fund, 2020-2022
- Neural Signatures of Pain Relief from Spinal Cord Stimulation, NIH/NCATS - Catalyst UCSF, 2021-2022
- Brain Rhythms and Episodic Memory Processes, NIH, 2009-2012
Publications (48)
Top publication keywords:
PainTheta RhythmPain ManagementSpinal Cord StimulationChronic PainMemoryMaze LearningSeptum of BrainNeuralgiaElectric StimulationHippocrateaceaeNeurophysiologyConsciousnessFornix, BrainElectric Stimulation Therapy
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First-in-human prediction of chronic pain state using intracranial neural biomarkers.
Nature neuroscience 2023 Shirvalkar P, Prosky J, Chin G, Ahmadipour P, Sani OG, Desai M, Schmitgen A, Dawes H, Shanechi MM, Starr PA, Chang EF -
How SAFE Is Real-world Use of Spinal Cord Stimulation Therapy for Chronic Pain?
JAMA neurology 2023 Shirvalkar P, Poree L -
Clinical trials in neuromodulatory treatment of drug-resistant hypertension and the need for spinal cord stimulation trials: a PRISMA systematic review.
Bioelectronic medicine 2024 Thrash GW, Wang E, Sun Y, Walker HC, Shirvalkar P, Becker BK, Holland MT -
Neuropathic pain - A clinical primer.
International review of neurobiology 2024 Shirvalkar P, de Andrade DC -
ID: 334564 EEG Signatures of Epidural Spinal Cord Stimulation: A Dosing and Mechanism of Action Study.
Neuromodulation Technology at the Neural Interface 2024 Chad Sitgraves, Prasad Shirvalkar, Lawrence Poree
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ID: 334648 Brain Mapping with Stereoelectroencephalography Reveals Altered Network Topologies in Chronic Pain.
Neuromodulation Technology at the Neural Interface 2024 Ishan Kanungo, Tony Liu, Julian Motzkin, Prasad Shirvalkar -
Neuromodulation for Neuropathic Pain Syndromes.
Continuum (Minneapolis, Minn.) 2024 Shirvalkar P -
Human Cervical Epidural Spinal Electrogram Topographically Maps Distinct Volitional Movements.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2024 Shukla PD, Burke JF, Kunwar N, Presbrey K, Balakid J, Yaroshinsky M, Louie K, Jacques L, Shirvalkar P, Wang DD -
Ambulatory Brain Biomarkers of Chronic Pain: Towards Closed Loop Brain Stimulation.
Biological Psychiatry 2024 Prasad Shirvalkar, Philip A. Starr, Edward F. Chang -
Editorial: Advancements in deep brain stimulation for chronic pain control.
Frontiers in pain research (Lausanne, Switzerland) 2023 Staudt MD, Yaghi NK, Mazur-Hart DJ, Shirvalkar P -
Quantifying Pain Location and Intensity with Multimodal Pain Body Diagrams.
Journal of visualized experiments : JoVE 2023 Kwong J, Lin J, Leriche R, Wozny TA, Shaughnessy A, Schmitgen A, Shirvalkar P -
Network targets for therapeutic brain stimulation: towards personalized therapy for pain.
Frontiers in pain research (Lausanne, Switzerland) 2023 Motzkin JC, Kanungo I, D'Esposito M, Shirvalkar P -
ID: 221565 EEG Signatures of Epidural Spinal Cord Stimulation: A Dosing and Mechanism of Action Study.
Neuromodulation Technology at the Neural Interface 2023 Chad Sitgraves, Prasad Shirvalkar, Lawrence Poree -
Proceedings of the Ninth Annual Deep Brain Stimulation Think Tank: Advances in Cutting Edge Technologies, Artificial Intelligence, Neuromodulation, Neuroethics, Pain, Interventional Psychiatry, Epilepsy, and Traumatic Brain Injury.
Frontiers in human neuroscience 2022 Wong JK, Deuschl G, Wolke R, Bergman H, Muthuraman M, Groppa S, Sheth SA, Bronte-Stewart HM, Wilkins KB, Petrucci MN, Lambert E, Kehnemouyi Y, Starr PA, Little S, Anso J, Gilron R, Poree L, … -
Practical Closed-Loop Strategies for Deep Brain Stimulation: Lessons From Chronic Pain.
Frontiers in neuroscience 2021 Prosky J, Cagle J, Sellers KK, Gilron R, de Hemptinne C, Schmitgen A, Starr PA, Chang EF, Shirvalkar P -
Epidural Spinal Electrogram Provides Direct Spinal Recordings in Awake Human Participants.
Frontiers in human neuroscience 2021 Burke JF, Kunwar N, Yaroshinsky MS, Louie KH, Shirvalkar P, Su P, Henry M, Pasvankas G, Poree L, Jacques L, Wang DD -
Corrigendum: Proceedings of the Eighth Annual Deep Brain Stimulation Think Tank: Advances in Optogenetics, Ethical Issues Affecting DBS Research, Neuromodulatory Approaches for Depression, Adaptive Neurostimulation, and Emerging DBS Technologies.
Frontiers in human neuroscience 2021 Vedam-Mai V, Deisseroth K, Giordano J, Lazaro-Munoz G, Chiong W, Suthana N, Langevin JP, Gill J, Goodman W, Provenza NR, Halpern CH, Shivacharan RS, Cunningham TN, Sheth SA, Pouratian N, Scangos KW, … -
High-Frequency Impulse Therapy for Treatment of Chronic Back Pain: A Multicenter Randomized Controlled Pilot Study.
Journal of pain research 2021 Amirdelfan K, Hong M, Tay B, Reddy S, Reddy V, Yang M, Khanna K, Shirvalkar P, Abrecht C, Gulati A -
Analysis-rcs-data: Open-Source Toolbox for the Ingestion, Time-Alignment, and Visualization of Sense and Stimulation Data From the Medtronic Summit RC+S System.
Frontiers in human neuroscience 2021 Sellers KK, Gilron R, Anso J, Louie KH, Shirvalkar PR, Chang EF, Little SJ, Starr PA -
Emerging Therapies for the Treatment of Complex Regional Pain Syndrome.
2021 Po-Yi Paul Su, Shikha Sharma, Prasad Shirvalkar, Lawrence Poree -
Musical Hallucinations in Chronic Pain: The Anterior Cingulate Cortex Regulates Internally Generated Percepts.
Frontiers in neurology 2021 Schmitgen A, Saal J, Sankaran N, Desai M, Joseph I, Starr P, Chang EF, Shirvalkar P -
Proceedings of the Eighth Annual Deep Brain Stimulation Think Tank: Advances in Optogenetics, Ethical Issues Affecting DBS Research, Neuromodulatory Approaches for Depression, Adaptive Neurostimulation, and Emerging DBS Technologies.
Frontiers in human neuroscience 2021 Vedam-Mai V, Deisseroth K, Giordano J, Lazaro-Munoz G, Chiong W, Suthana N, Langevin JP, Gill J, Goodman W, Provenza NR, Halpern CH, Shivacharan RS, Cunningham TN, Sheth SA, Pouratian N, Scangos KW, … -
The American Society of Pain and Neuroscience (ASPN) Practical Guidelines to Study Design and Scientific Manuscript Preparation in Neuromodulation.
Journal of pain research 2021 Eshraghi Y, Chakravarthy K, Strand NH, Shirvalkar P, Schuster NM, Abdallah RT, Vallejo R, Sayed D, Kim D, Kim C, Meacham K, Deer T, Translational Research Committee American Society of Pain and … -
A Tale of Two Cords: Diastematomyelia.
Pain Medicine 2021 Westin Tom, Thoha Pham, Prasad Shirvalkar -
A Deep Brain Stimulation Trial Period for Treating Chronic Pain.
Journal of clinical medicine 2020 Shirvalkar P, Sellers KK, Schmitgen A, Prosky J, Joseph I, Starr PA, Chang EF -
A Comprehensive Practice Guideline for Magnetic Resonance Imaging Compatibility in Implanted Neuromodulation Devices.
Neuromodulation : journal of the International Neuromodulation Society 2020 Sayed D, Chakravarthy K, Amirdelfan K, Kalia H, Meacham K, Shirvalkar P, Falowski S, Petersen E, Hagedorn JM, Pope J, Leever J, ASPN MRI Compatibility Working Group, Deer T -
Cognitive Effects of Limbic Deep Brain Stimulation in Patients with Refractory Chronic Neuropathic Pain (1990).
Neurology 2020 Gregory Chin, Heather Dawes, Edward Chang, Prasad Shirvalkar -
Decoding Acute and Chronic Pain State from Ambulatory Intracranial Recordings: Towards Closed-Loop Brain Stimulation (233).
Neurology 2020 Prasad Shirvalkar, Gregory Chin, Heather Dawes, Philip Starr, Edward Chang -
Transcranial Magnetic Stimulation for Pain, Headache, and Comorbid Depression: INS-NANS Expert Consensus Panel Review and Recommendation.
Neuromodulation : journal of the International Neuromodulation Society 2020 Leung A, Shirvalkar P, Chen R, Kuluva J, Vaninetti M, Bermudes R, Poree L, Wassermann EM, Kopell B, Levy R, and the Expert Consensus Panel -
Large expert-curated database for benchmarking document similarity detection in biomedical literature search.
Database 2019 eter Brown, Aik-Choon Tan, Mohamed A El-Esawi, Thomas Liehr, Oliver Blanck, Douglas P Gladue, Gabriel M F Almeida, Tomislav Cernava, Carlos O Sorzano, Andy W K Yeung, Michael S Engel, Arun Richard … -
Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain.
Frontiers in computational neuroscience 2018 Shirvalkar P, Veuthey TL, Dawes HE, Chang EF -
Chapter 47 The Development of Algorithms for Pain Care Including Neuromodulation Therapies Introducing the SAFE Principles.
Neuromodulation 2018 Prasad Shirvalkar, Lawrence R. Poree, Elliot S. Krames -
List of Contributors of Volume 2.
Neuromodulation 2018 Al-Kaisy Adnan, Andreas Alexopoulos, Kenneth M. Alo, Ron L. Alterman, Arun Amar, Pablo Andrade, Sailesh Arulkumar, Ahmed J. Awad, Gordon Baltuch, Giancarlo Barolat, Ernest J. Barthélemy, Neil U. Barua… -
Improving lower limb strength in incomplete spinal cord injury with non-invasive spinal associative stimulation.
Brain Stimulation 2017 M. Cortes, G. Thickbroom, J. Valls-Sole, P. Shirvalkar, A. Pascual-Leone, D. Edwards -
Amyloid-Beta Related Angitiis and Reversible Cerebral Vasoconstriction Syndrome: A Case Report (P6.057).
Neurology 2016 Thomas Tropea, Prasad Shirvalkar, Krithiga Sekar, Kyung-Wha Kim, Apostolos Tsiouris, Ehud Lavi, Alan Segal -
Conference Curriculum Content and Organization in United States Neurology Residencies: A Cross-Sectional Survey (P2.354).
Neurology 2016 Arthie Jeyakumar, Pravin Khemani, Ralph Jozefowicz, Prasad Shirvalkar, Augusto Miravalle, Constantine Farmakidis -
American neuroborreliosis presenting as cranial polyneuritis and radiculoneuritis.
Neurology(R) neuroimmunology & neuroinflammation 2014 Wang E, Shirvalkar PR, Maciel CB, Merkler AE, Safdieh J, Gupta A -
Widespread Leptomeningeal Involvement in Borreliosis (P2.317).
Neurology 2014 Carolina Maciel, Erwin Wang, Prasad Shirvalkar, Alexander Merkler, Joseph Safdieh -
Memory-guided learning: CA1 and CA3 neuronal ensembles differentially encode the commonalities and differences between situations.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 Bahar AS, Shirvalkar PR, Shapiro ML -
Memory modulates journey-dependent coding in the rat hippocampus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 Ferbinteanu J, Shirvalkar P, Shapiro ML -
Design and Construction of a Cost Effective Headstage for Simultaneous Neural Stimulation and Recording in the Water Maze.
Journal of Visualized Experiments 2010 Prasad R. Shirvalkar, Mathew L. Shapiro -
Design and construction of a cost effective headstage for simultaneous neural stimulation and recording in the water maze.
Journal of visualized experiments : JoVE 2010 Shirvalkar PR, Shapiro ML -
Infrageniculate Interventions in Female Patients: Improved Patency Rates but Higher Rates of Postoperative Complications.
Journal of Vascular Surgery 2010 Tejas R. Shah, Angeliki Vouyouka, Daniel K. Han, Sharif Ellozy, Robert Lookstein, Prasad Shirvalkar, Michael Marin, Peter L. Faries -
Bidirectional changes to hippocampal theta-gamma comodulation predict memory for recent spatial episodes.
Proceedings of the National Academy of Sciences of the United States of America 2010 Shirvalkar PR, Rapp PR, Shapiro ML -
The multiple origins and laminar topography of the hippocampal theta rhythm.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 Shirvalkar P, Bahar AS -
Hippocampal neural assemblies and conscious remembering.
Journal of neurophysiology 2009 Shirvalkar PR -
Cognitive enhancement with central thalamic electrical stimulation.
Proceedings of the National Academy of Sciences of the United States of America 2006 Shirvalkar P, Seth M, Schiff ND, Herrera DG -
Regulation of neurogenesis in the aging vertebrate brain: role of oxidative stress and neuropsychiatric factors.
Clinical Neuroscience Research 2003 Evelyn Kim, Prasad Shirvalkar, Daniel G. Herrera