Pooja Middha, PhD
Postdoctoral Scholar
Medicine
School of Medicine

Publications (21)

Top publication keywords:
Gene-Environment InteractionColitisNicotineCrohn DiseaseReceptors, EstrogenFanconi Anemia Complementation Group C ProteinLung NeoplasmsColitis, UlcerativeGenome-Wide Association StudySmokingCarcinoma, Non-Small-Cell LungBreast NeoplasmsTarsbeta CaroteneGenetic Predisposition to Disease

• Risk factors for breast cancer subtypes by race and ethnicity: A scoping review.
  Journal of the National Cancer Institute 2024 Hurson AN, Ahearn TU, Koka H, Jenkins BD, Harris AR, Roberts S, Fan S, Franklin J, Butera G, Keeman R, Jung AY, Middha P, Gierach GL, Yang XR, Chang-Claude J, Tamimi RM, Troester MA, Bandera EV, …
• Germline prediction of immune checkpoint inhibitor discontinuation for immune-related adverse events.
  medRxiv : the preprint server for health sciences 2024 Middha P, Thummalapalli R, Quandt Z, Balaratnam K, Cardenas E, Falcon CJ, Princess Margaret Lung Group, Gubens MA, Huntsman S, Khan K, Li M, Lovly CM, Patel D, Zhan LJ, Liu G, Aldrich MC, Schoenfeld …
• Polygenic risk score for ulcerative colitis predicts immune checkpoint inhibitor-mediated colitis.
  Nature communications 2024 Middha P, Thummalapalli R, Betti MJ, Yao L, Quandt Z, Balaratnam K, Bejan CA, Cardenas E, Falcon CJ, Faleck DM, Princess Margaret Lung Group, Gubens MA, Huntsman S, Johnson DB, Kachuri L, Khan K, Li M…
• Risk factors for breast cancer subtypes by race and ethnicity: A scoping review of the literature.
  medRxiv : the preprint server for health sciences 2024 Hurson AN, Ahearn TU, Koka H, Jenkins BD, Harris AR, Roberts S, Fan S, Franklin J, Butera G, Keeman R, Jung AY, Middha P, Gierach GL, Yang XR, Chang-Claude J, Tamimi RM, Troester MA, Bandera EV, …
• Polygenic risk score for ulcerative colitis predicts immune checkpoint inhibitor-mediated colitis.
  medRxiv : the preprint server for health sciences 2023 Middha P, Thummalapalli R, Betti MJ, Yao L, Quandt Z, Balaratnam K, Bejan CA, Cardenas E, Falcon CJ, Faleck DM, Princess Margaret Lung Group, Gubens MA, Huntsman S, Johnson DB, Kachuri L, Khan K, Li M…

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• A genome-wide gene-environment interaction study of breast cancer risk for women of European ancestry.
  Breast cancer research : BCR 2023 Middha P, Wang X, Behrens S, Bolla MK, Wang Q, Dennis J, Michailidou K, Ahearn TU, Andrulis IL, Anton-Culver H, Arndt V, Aronson KJ, Auer PL, Augustinsson A, Baert T, Freeman LEB, Becher H, Beckmann …
• Development and testing of a polygenic risk score for breast cancer aggressiveness.
  NPJ precision oncology 2023 Shieh Y, Roger J, Yau C, Wolf DM, Hirst GL, Swigart LB, Huntsman S, Hu D, Nierenberg JL, Middha P, Heise RS, Shi Y, Kachuri L, Zhu Q, Yao S, Ambrosone CB, Kwan ML, Caan BJ, Witte JS, Kushi LH, 't Veer…
• Distinct Reproductive Risk Profiles for Intrinsic-Like Breast Cancer Subtypes: Pooled Analysis of Population-Based Studies.
  Journal of the National Cancer Institute 2022 Jung AY, Ahearn TU, Behrens S, Middha P, Bolla MK, Wang Q, Arndt V, Aronson KJ, Augustinsson A, Beane Freeman LE, Becher H, Brenner H, Canzian F, Carey LA, CTS Consortium, Czene K, Eliassen AH, …
• Combined Associations of a Polygenic Risk Score and Classical Risk Factors With Breast Cancer Risk.
  Journal of the National Cancer Institute 2021 Kapoor PM, Mavaddat N, Choudhury PP, Wilcox AN, Lindström S, Behrens S, Michailidou K, Dennis J, Bolla MK, Wang Q, Jung A, Abu-Ful Z, Ahearn T, Andrulis IL, Anton-Culver H, Arndt V, Aronson KJ, Auer …
• Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses.
  Nature genetics 2020 Zhang H, Ahearn TU, Lecarpentier J, Barnes D, Beesley J, Qi G, Jiang X, O'Mara TA, Zhao N, Bolla MK, Dunning AM, Dennis J, Wang Q, Ful ZA, Aittomäki K, Andrulis IL, Anton-Culver H, Arndt V, Aronson KJ…
• Transcriptome-wide association study of breast cancer risk by estrogen-receptor status.
  Genetic epidemiology 2020 Feng H, Gusev A, Pasaniuc B, Wu L, Long J, Abu-Full Z, Aittomäki K, Andrulis IL, Anton-Culver H, Antoniou AC, Arason A, Arndt V, Aronson KJ, Arun BK, Asseryanis E, Auer PL, Azzollini J, Balmaña J, …
• Assessment of interactions between 205 breast cancer susceptibility loci and 13 established risk factors in relation to breast cancer risk, in the Breast Cancer Association Consortium.
  International journal of epidemiology 2020 Kapoor PM, Lindström S, Behrens S, Wang X, Michailidou K, Bolla MK, Wang Q, Dennis J, Dunning AM, Pharoah PDP, Schmidt MK, Kraft P, García-Closas M, Easton DF, Milne RL, Chang-Claude J, Breast Cancer …
• A network analysis to identify mediators of germline-driven differences in breast cancer prognosis.
  Nature communications 2020 Escala-Garcia M, Abraham J, Andrulis IL, Anton-Culver H, Arndt V, Ashworth A, Auer PL, Auvinen P, Beckmann MW, Beesley J, Behrens S, Benitez J, Bermisheva M, Blomqvist C, Blot W, Bogdanova NV, Bojesen…
• Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes.
  Nature genetics 2020 Fachal L, Aschard H, Beesley J, Barnes DR, Allen J, Kar S, Pooley KA, Dennis J, Michailidou K, Turman C, Soucy P, Lemaçon A, Lush M, Tyrer JP, Ghoussaini M, Moradi Marjaneh M, Jiang X, Agata S, …
• Publisher Correction: Shared heritability and functional enrichment across six solid cancers.
  Nature communications 2019 Jiang X, Finucane HK, Schumacher FR, Schmit SL, Tyrer JP, Han Y, Michailidou K, Lesseur C, Kuchenbaecker KB, Dennis J, Conti DV, Casey G, Gaudet MM, Huyghe JR, Albanes D, Aldrich MC, Andrew AS, …
• Two truncating variants in FANCC and breast cancer risk.
  Scientific reports 2019 Dörk T, Peterlongo P, Mannermaa A, Bolla MK, Wang Q, Dennis J, Ahearn T, Andrulis IL, Anton-Culver H, Arndt V, Aronson KJ, Augustinsson A, Freeman LEB, Beckmann MW, Beeghly-Fadiel A, Behrens S, …
• β-Carotene Supplementation and Lung Cancer Incidence in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study: The Role of Tar and Nicotine.
  Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2019 Middha P, Weinstein SJ, Männistö S, Albanes D, Mondul AM
• Genome-wide association study of germline variants and breast cancer-specific mortality.
  British journal of cancer 2019 Escala-Garcia M, Guo Q, Dörk T, Canisius S, Keeman R, Dennis J, Beesley J, Lecarpentier J, Bolla MK, Wang Q, Abraham J, Andrulis IL, Anton-Culver H, Arndt V, Auer PL, Beckmann MW, Behrens S, Benitez J…
• Shared heritability and functional enrichment across six solid cancers.
  Nature communications 2019 Jiang X, Finucane HK, Schumacher FR, Schmit SL, Tyrer JP, Han Y, Michailidou K, Lesseur C, Kuchenbaecker KB, Dennis J, Conti DV, Casey G, Gaudet MM, Huyghe JR, Albanes D, Aldrich MC, Andrew AS, …
• Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes.
  American journal of human genetics 2018 Mavaddat N, Michailidou K, Dennis J, Lush M, Fachal L, Lee A, Tyrer JP, Chen TH, Wang Q, Bolla MK, Yang X, Adank MA, Ahearn T, Aittomäki K, Allen J, Andrulis IL, Anton-Culver H, Antonenkova NN, Arndt …
• Current Applications of Genetic Risk Scores to Cardiovascular Outcomes and Subclinical Phenotypes.
  Current epidemiology reports 2015 Smith JA, Ware EB, Middha P, Beacher L, Kardia SL