Philippe Gui, PhD, MSc
Associate Specialist
Medicine
School of Medicine

Publications (11)

Top publication keywords:
ImmunotherapyCell MovementCyclin-Dependent Kinase Inhibitor p27rho-Associated KinasesNeoplasm, ResidualOtitisLeukemia, Myeloid, AcuteLung NeoplasmsPhenylalanineGenomerho GTP-Binding ProteinsMacrophagesOncogene Protein p21(ras)Matrix MetalloproteinasesNeoplasms

• The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance.
  Nature genetics 2023 Caswell DR, Gui P, Mayekar MK, Law EK, Pich O, Bailey C, Boumelha J, Kerr DL, Blakely CM, Manabe T, Martinez-Ruiz C, Bakker B, De Dios Palomino Villcas J, I Vokes N, Dietzen M, Angelova M, Gini B, …
• Author Correction: 3-Phosphoinositide-dependent kinase 1 drives acquired resistance to osimertinib.
  Communications biology 2023 Meraz IM, Majidi M, Fang B, Meng F, Gao L, Shao R, Song R, Li F, Lissanu Y, Chen H, Ha MJ, Wang Q, Wang J, Shpall E, Jung SY, Haderk F, Gui P, Riess JW, Olivas V, Bivona TG, Roth JA
• 3-Phosphoinositide-dependent kinase 1 drives acquired resistance to osimertinib.
  Communications biology 2023 Meraz IM, Majidi M, Fang B, Meng F, Gao L, Shao R, Song R, Li F, Lissanu Y, Chen H, Ha MJ, Wang Q, Wang J, Shpall E, Jung SY, Haderk F, Gui P, Riess JW, Olivas V, Bivona TG, Roth JA
• Evolution of metastasis: new tools and insights.
  Trends in cancer 2021 Gui P, Bivona TG
• Stepwise evolution of therapy resistance in AML.
  Cancer cell 2021 Gui P, Bivona TG

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• Therapy-Induced Evolution of Human Lung Cancer Revealed by Single-Cell RNA Sequencing.
  Cell 2020 Maynard A, McCoach CE, Rotow JK, Harris L, Haderk F, Kerr DL, Yu EA, Schenk EL, Tan W, Zee A, Tan M, Gui P, Lea T, Wu W, Urisman A, Jones K, Sit R, Kolli PK, Seeley E, Gesthalter Y, Le DD, Yamauchi KA…
• Co-occurring Alterations in the RAS-MAPK Pathway Limit Response to MET Inhibitor Treatment in MET Exon 14 Skipping Mutation-Positive Lung Cancer.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2019 Rotow JK, Gui P, Wu W, Raymond VM, Lanman RB, Kaye FJ, Peled N, Fece de la Cruz F, Nadres B, Corcoran RB, Yeh I, Bastian BC, Starostik P, Newsom K, Olivas VR, Wolff AM, Fraser JS, Collisson EA, …
• Synthetic Essentiality of Metabolic Regulator PDHK1 in PTEN-Deficient Cells and Cancers.
  Cell reports 2019 Chatterjee N, Pazarentzos E, Mayekar MK, Gui P, Allegakoen DV, Hrustanovic G, Olivas V, Lin L, Verschueren E, Johnson JR, Hofree M, Yan JJ, Newton BW, Dollen JV, Earnshaw CH, Flanagan J, Chan E, …
• The Protease-Dependent Mesenchymal Migration of Tumor-Associated Macrophages as a Target in Cancer Immunotherapy.
  Cancer immunology research 2018 Gui P, Ben-Neji M, Belozertseva E, Dalenc F, Franchet C, Gilhodes J, Labrousse A, Bellard E, Golzio M, Poincloux R, Maridonneau-Parini I, Le Cabec V
• Rho/ROCK pathway inhibition by the CDK inhibitor p27(kip1) participates in the onset of macrophage 3D-mesenchymal migration.
  Journal of cell science 2014 Gui P, Labrousse A, Van Goethem E, Besson A, Maridonneau-Parini I, Le Cabec V
• Immune cell Toll-like receptor 4 mediates the development of obesity- and endotoxemia-associated adipose tissue fibrosis.
  Cell reports 2014 Vila IK, Badin PM, Marques MA, Monbrun L, Lefort C, Mir L, Louche K, Bourlier V, Roussel B, Gui P, Grober J, Štich V, Rossmeislová L, Zakaroff-Girard A, Bouloumié A, Viguerie N, Moro C, Tavernier G, …