Philip Starr
Professor
Neurological Surgery
School of Medicine
Philip.Starr@ucsf.edu 415-502-2885
Dr. Starr is Professor of Neurological Surgery and holds the Dolores Cakebread Endowed Chair in Neurological Surgery. His clinical interests are in functional neurosurgery, especially in the use of implanted devices to improve brain function.
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He is co-director, with Dr. Jill Ostrem, of the UCSF Surgical Movement Disorders clinic, a multidisciplinary clinic serving a large population of patients with Parkinson’s disease, dystonia, and tremor. In 2013, this clinic was designated as a Bachman-Strauss Center of Excellence in the treatment of movement disorders, one of four such Centers of Excellence in the United States. Dr. Starr directs an NIH-funded laboratory devoted to analyzing how movement disorders affect the network function of the brain, understanding the central mechanisms of therapeutic neurostimulation, and improving the effectiveness of neurostimulion.
Dr. Starr and colleagues pioneered the use of electrocorticography (direct brain recording using an implanted cortical electrode) as a tool to understand Parkinson’s disease and dystonia. In 2013, this effort culminated in the first implant of a chronic multi-site (cortex and basal ganglia) brain recording device in a patient with Parkinson’s disease, as part of a ten patient study of a novel, totally implantable bidirectional neural interface. With Dr. Paul Larson and Dr. Alastair Martin, he has developed a new approach to improve the accuracy of delivery of devices and drugs to deep brain targets using interventional MRI, in conjunction with a skull mounted aiming device and a dedicated software system (Clearpoint system, MRI interventions).
Awards
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- finalist, Israeli B.R.A.I.N. prize in neurotechnology, 2013
- Dolores Cakebread Endowed Chair in Neurological Surgery, 2005
Education & Training
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- Diversity, Equity, and Inclusion Champion Training University of California 2019
- M.D. School of Medicine Harvard University 1989
Interests
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- electrocorticography
- dystonia
- Parkinson's disease
- basal ganglia physiology
- deep brain stimulation
Websites
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- Clinical Profile at UCSF Medical Center (ucsfhealth.org)
- Profile at UCSF Neurosurgery (neurosurgery.ucsf.edu)
- Starr laboratory (neurosurgery.ucsf.edu)
Videos
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- Kavli Faculty Seminar (lecture.ucsf.edu)
Grants and Projects
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- Technology development for closed-loop deep brain stimulation to treat refractory neuropathic pain, NIH/NINDS, 2019-2024
- The motor network in Parkinson's disease: mechanisms of therapy, NIH/NINDS, 2014-2024
- Closed loop deep brain stimulation for Parkinson's disease, NIH/NINDS, 2016-2022
- Fabrication and testing of next generation cortical paddle leads for bidirectional neural interfaces, NIH/NIMH, 2019-2021
- Cortical and basal ganglia local field potentials in human movement disorders, NIH/NINDS, 2010-2015
- Cortical and basal ganglia local field potentials in human movement disorders, NIH/NINDS, 2010-2014
- General Clinical Research Center, NIH, 1984-2010
- Pallidal Physiology in Human and Primate Dystonia, NIH/NINDS, 2000-2007
Publications (158)
Top publication keywords:
Globus PallidusDystoniaSubthalamic NucleusParkinson DiseaseDeep Brain Stimulation
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Subthalamic nucleus neurons are synchronized to primary motor cortex local field potentials in Parkinson's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Shimamoto SA, Ryapolova-Webb ES, Ostrem JL, Galifianakis NB, Miller KJ, Starr PA -
Exaggerated phase-amplitude coupling in the primary motor cortex in Parkinson disease.
Proceedings of the National Academy of Sciences of the United States of America 2013 de Hemptinne C, Ryapolova-Webb ES, Air EL, Garcia PA, Miller KJ, Ojemann JG, Ostrem JL, Galifianakis NB, Starr PA -
Oscillations in sensorimotor cortex in movement disorders: an electrocorticography study.
Brain : a journal of neurology 2012 Crowell AL, Ryapolova-Webb ES, Ostrem JL, Galifianakis NB, Shimamoto S, Lim DA, Starr PA -
Deep brain stimulation in children: experience and technical pearls.
Journal of neurosurgery. Pediatrics 2011 Air EL, Ostrem JL, Sanger TD, Starr PA -
Subthalamic nucleus deep brain stimulation in primary cervical dystonia.
Neurology 2011 Ostrem JL, Racine CA, Glass GA, Grace JK, Volz MM, Heath SL, Starr PA -
Intraoperative computed tomography for deep brain stimulation surgery: technique and accuracy assessment.
Neurosurgery 2011 Shahlaie K, Larson PS, Starr PA -
Pallidal versus subthalamic deep-brain stimulation for Parkinson's disease.
The New England journal of medicine 2010 Follett KA, Weaver FM, Stern M, Hur K, Harris CL, Luo P, Marks WJ, Rothlind J, Sagher O, Moy C, Pahwa R, Burchiel K, Hogarth P, Lai EC, Duda JE, Holloway K, Samii A, Horn S, Bronstein JM, Stoner G, … -
Subthalamic nucleus deep brain stimulator placement using high-field interventional magnetic resonance imaging and a skull-mounted aiming device: technique and application accuracy.
Journal of neurosurgery 2010 Starr PA, Martin AJ, Ostrem JL, Talke P, Levesque N, Larson PS -
The subthalamic nucleus in primary dystonia: single-unit discharge characteristics.
Journal of neurophysiology 2009 Schrock LE, Ostrem JL, Turner RS, Shimamoto SA, Starr PA -
Physiological identification of the human pedunculopontine nucleus.
Journal of neurology, neurosurgery, and psychiatry 2009 Shimamoto SA, Larson PS, Ostrem JL, Glass GA, Turner RS, Starr PA -
The neurophysiology and effect of deep brain stimulation in a patient with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism.
Journal of neurosurgery 2009 Christine CW, Langston JW, Turner RS, Starr PA -
Pallidal neuronal discharge in Huntington's disease: support for selective loss of striatal cells originating the indirect pathway.
Experimental neurology 2008 Starr PA, Kang GA, Heath S, Shimamoto S, Turner RS -
Deep brain stimulator hardware-related infections: incidence and management in a large series.
Neurosurgery 2008 Sillay KA, Larson PS, Starr PA -
Neuronal responses to passive movement in the globus pallidus internus in primary dystonia.
Journal of neurophysiology 2007 Chang EF, Turner RS, Ostrem JL, Davis VR, Starr PA -
Pallidal deep brain stimulation in patients with cranial-cervical dystonia (Meige syndrome).
Movement disorders : official journal of the Movement Disorder Society 2007 Ostrem JL, Marks WJ, Volz MM, Heath SL, Starr PA -
Microelectrode-guided implantation of deep brain stimulators into the globus pallidus internus for dystonia: techniques, electrode locations, and outcomes.
Journal of neurosurgery 2006 Starr PA, Turner RS, Rau G, Lindsey N, Heath S, Volz M, Ostrem JL, Marks WJ -
Spontaneous pallidal neuronal activity in human dystonia: comparison with Parkinson's disease and normal macaque.
Journal of neurophysiology 2005 Starr PA, Rau GM, Davis V, Marks WJ, Ostrem JL, Simmons D, Lindsey N, Turner RS -
Locations of movement-related cells in the human subthalamic nucleus in Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2003 Theodosopoulos PV, Marks WJ, Christine C, Starr PA -
Implantation of deep brain stimulators into the subthalamic nucleus: technical approach and magnetic resonance imaging-verified lead locations.
Journal of neurosurgery 2002 Starr PA, Christine CW, Theodosopoulos PV, Lindsey N, Byrd D, Mosley A, Marks WJ
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Beta Oscillations in Working Memory, Executive Control of Movement and Thought, and Sensorimotor Function.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2019 Schmidt R, Herrojo Ruiz M, Kilavik BE, Lundqvist M, Starr PA, Aron AR -
Proceedings of the Sixth Deep Brain Stimulation Think Tank Modulation of Brain Networks and Application of Advanced Neuroimaging, Neurophysiology, and Optogenetics.
Frontiers in neuroscience 2019 Ramirez-Zamora A, Giordano J, Boyden ES, Gradinaru V, Gunduz A, Starr PA, Sheth SA, McIntyre CC, Fox MD, Vitek J, Vedam-Mai V, Akbar U, Almeida L, Bronte-Stewart HM, Mayberg HS, Pouratian N, Gittis AH… -
Washout of chronic therapeutic deep brain stimulation increases cortical phase-amplitude coupling.
Parkinsonism & related disorders 2019 Rajagopalan SS, Miller AM, de Hemptinne C, San Luciano M, Ostrem JL, Starr PA -
Altered Prefrontal Theta and Gamma Activity during an Emotional Face Processing Task in Parkinson Disease.
Journal of cognitive neuroscience 2019 Chen W, de Hemptinne C, Leibbrand M, Miller AM, Larson PS, Starr PA -
Patient Experience with Rechargeable Implantable Pulse Generator Deep Brain Stimulation for Movement Disorders.
Stereotactic and functional neurosurgery 2019 Mitchell KT, Volz M, Lee A, San Luciano M, Wang S, Starr PA, Larson P, Galifianakis NB, Ostrem JL -
Effect of levodopa on electroencephalographic biomarkers of the parkinsonian state.
Journal of neurophysiology 2019 Miller AM, Miocinovic S, Swann NC, Rajagopalan SS, Darevsky DM, Gilron R, de Hemptinne C, Ostrem JL, Starr PA -
Pallidal thermolesion unleashes gamma oscillations in the motor cortex in Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2019 de Hemptinne C, Wang DD, Miocinovic S, Chen W, Ostrem JL, Starr PA -
Long-Term Outcomes of Bilateral Pallidal Deep Brain Stimulation for X-Linked Dystonia and Parkinsonism.
Stereotactic and functional neurosurgery 2018 Kilbane C, Witt J, Galifianakis NB, Glass GA, Volz M, Heath S, Starr PA, Ostrem JL -
Surgical management of camptocormia in Parkinson's disease: systematic review and meta-analysis.
Journal of neurosurgery 2018 Chan AK, Chan AY, Lau D, Durcanova B, Miller CA, Larson PS, Starr PA, Mummaneni PV -
Cortical Potentials Evoked by Subthalamic Stimulation Demonstrate a Short Latency Hyperdirect Pathway in Humans.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2018 Miocinovic S, de Hemptinne C, Chen W, Isbaine F, Willie JT, Ostrem JL, Starr PA -
Totally Implantable Bidirectional Neural Prostheses: A Flexible Platform for Innovation in Neuromodulation.
Frontiers in neuroscience 2018 Starr PA -
Benefits and risks of unilateral and bilateral ventral intermediate nucleus deep brain stimulation for axial essential tremor symptoms.
Parkinsonism & related disorders 2018 Mitchell KT, Larson P, Starr PA, Okun MS, Wharen RE, Uitti RJ, Guthrie BL, Peichel D, Pahwa R, Walker HC, Foote K, Marshall FJ, Jankovic J, Simpson R, Phibbs F, Neimat JS, Stewart RM, Dashtipour K, … -
Adaptive deep brain stimulation for Parkinson's disease using motor cortex sensing.
Journal of neural engineering 2018 Swann NC, de Hemptinne C, Thompson MC, Miocinovic S, Miller AM, Gilron R, Ostrem JL, Chizeck HJ, Starr PA -
Pallidal Deep-Brain Stimulation Disrupts Pallidal Beta Oscillations and Coherence with Primary Motor Cortex in Parkinson's Disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2018 Wang DD, de Hemptinne C, Miocinovic S, Ostrem JL, Galifianakis NB, San Luciano M, Starr PA -
Venous Thromboembolism during Interventional MRI-Guided Stereotactic Surgery.
Stereotactic and functional neurosurgery 2018 Kundishora AJ, Englot DJ, Starr PA, Martin AJ, Larson PS -
Laser ablative therapy of sessile hypothalamic hamartomas in children using interventional MRI: report of 5 cases.
Journal of neurosurgery. Pediatrics 2018 Southwell DG, Birk HS, Larson PS, Starr PA, Sugrue LP, Auguste KI -
Evolving Applications, Technological Challenges and Future Opportunities in Neuromodulation: Proceedings of the Fifth Annual Deep Brain Stimulation Think Tank.
Frontiers in neuroscience 2018 Ramirez-Zamora A, Giordano JJ, Gunduz A, Brown P, Sanchez JC, Foote KD, Almeida L, Starr PA, Bronte-Stewart HM, Hu W, McIntyre C, Goodman W, Kumsa D, Grill WM, Walker HC, Johnson MD, Vitek JL, Greene … -
Cortical gamma oscillations in isolated dystonia.
Parkinsonism & related disorders 2018 Miocinovic S, Swann NC, de Hemptinne C, Miller A, Ostrem JL, Starr PA -
Deep Brain Stimulation: Interventional and Intraoperative MRI Approaches.
Progress in neurological surgery 2018 Larson PS, Starr PA, Martin AJ -
Before and after the veterans affairs cooperative program 468 study: Deep brain stimulator target selection for treatment of Parkinson's disease.
Parkinsonism & related disorders 2017 Southwell DG, Rutkowski MJ, San Luciano M, Racine C, Ostrem J, Starr PA, Larson PS -
Chronic deep brain stimulation normalizes scalp EEG activity in isolated dystonia.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2017 Miocinovic S, Miller A, Swann NC, Ostrem JL, Starr PA -
Hemorrhage Detection and Incidence during Magnetic Resonance-Guided Deep Brain Stimulator Implantations.
Stereotactic and functional neurosurgery 2017 Martin AJ, Starr PA, Ostrem JL, Larson PS -
Thalamic deep brain stimulation for orthostatic tremor: A multicenter international registry.
Movement disorders : official journal of the Movement Disorder Society 2017 Merola A, Fasano A, Hassan A, Ostrem JL, Contarino MF, Lyons M, Krauss JK, Wolf ME, Klassen BT, van Rootselaar AF, Regidor I, Duker AP, Ondo W, Guridi J, Volkmann J, Wagle Shukla A, Mandybur GT, Okun … -
Nonsinusoidal Beta Oscillations Reflect Cortical Pathophysiology in Parkinson's Disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2017 Cole SR, van der Meij R, Peterson EJ, de Hemptinne C, Starr PA, Voytek B -
Parkinson's disease patient preference and experience with various methods of DBS lead placement.
Parkinsonism & related disorders 2017 LaHue SC, Ostrem JL, Galifianakis NB, San Luciano M, Ziman N, Wang S, Racine CA, Starr PA, Larson PS, Katz M -
Chronic multisite brain recordings from a totally implantable bidirectional neural interface: experience in 5 patients with Parkinson's disease.
Journal of neurosurgery 2017 Swann NC, de Hemptinne C, Miocinovic S, Qasim S, Ostrem JL, Galifianakis NB, Luciano MS, Wang SS, Ziman N, Taylor R, Starr PA -
Subthalamic nucleus deep brain stimulation in isolated dystonia: A 3-year follow-up study.
Neurology 2016 Ostrem JL, San Luciano M, Dodenhoff KA, Ziman N, Markun LC, Racine CA, de Hemptinne C, Volz MM, Heath SL, Starr PA -
Proceedings of the Fourth Annual Deep Brain Stimulation Think Tank: A Review of Emerging Issues and Technologies.
Frontiers in integrative neuroscience 2016 Deeb W, Giordano JJ, Rossi PJ, Mogilner AY, Gunduz A, Judy JW, Klassen BT, Butson CR, Van Horne C, Deny D, Dougherty DD, Rowell D, Gerhardt GA, Smith GS, Ponce FA, Walker HC, Bronte-Stewart HM, … -
Proceedings of the Eighth International Workshop on Advances in Electrocorticography.
Epilepsy & behavior : E&B 2016 Ritaccio AL, Williams J, Denison T, Foster BL, Starr PA, Gunduz A, Zijlmans M, Schalk G -
An unexpectedly high rate of revisions and removals in deep brain stimulation surgery: Analysis of multiple databases.
Parkinsonism & related disorders 2016 Rolston JD, Englot DJ, Starr PA, Larson PS -
Neurofeedback Control in Parkinsonian Patients Using Electrocorticography Signals Accessed Wirelessly With a Chronic, Fully Implanted Device.
IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society 2016 Khanna P, Swann NC, de Hemptinne C, Miocinovic S, Miller A, Starr PA, Carmena JM -
Gamma Oscillations in the Hyperkinetic State Detected with Chronic Human Brain Recordings in Parkinson's Disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2016 Swann NC, de Hemptinne C, Miocinovic S, Qasim S, Wang SS, Ziman N, Ostrem JL, San Luciano M, Galifianakis NB, Starr PA -
Comparison of Deep Brain Stimulation Lead Targeting Accuracy and Procedure Duration between 1.5- and 3-Tesla Interventional Magnetic Resonance Imaging Systems: An Initial 12-Month Experience.
Stereotactic and functional neurosurgery 2016 Southwell DG, Narvid JA, Martin AJ, Qasim SE, Starr PA, Larson PS -
Deep brain stimulator implantation in a diagnostic MRI suite: infection history over a 10-year period.
Journal of neurosurgery 2016 Martin AJ, Larson PS, Ziman N, Levesque N, Volz M, Ostrem JL, Starr PA -
Bilateral Ventral Intermediate Nucleus Thalamic Deep Brain Stimulation in Orthostatic Tremor.
Stereotactic and functional neurosurgery 2016 Coleman RR, Starr PA, Katz M, Glass GA, Volz M, Khandhar SM, Ostrem JL -
Pregnancy in a Series of Dystonia Patients Treated with Deep Brain Stimulation: Outcomes and Management Recommendations.
Stereotactic and functional neurosurgery 2016 Ziman N, Coleman RR, Starr PA, Volz M, Marks WJ, Walker HC, Guthrie SL, Ostrem JL -
Intraoperative electrocorticography for physiological research in movement disorders: principles and experience in 200 cases.
Journal of neurosurgery 2016 Panov F, Levin E, de Hemptinne C, Swann NC, Qasim S, Miocinovic S, Ostrem JL, Starr PA -
Subthalamic local field potentials in Parkinson's disease and isolated dystonia: An evaluation of potential biomarkers.
Neurobiology of disease 2016 Wang DD, de Hemptinne C, Miocinovic S, Qasim SE, Miller AM, Ostrem JL, Galifianakis NB, San Luciano M, Starr PA -
Effective Interventional Magnetic Resonance Image-Guided Laser Ablations in a Parkinson's Disease Patient with Refractory Tremor.
Movement disorders clinical practice 2015 San Luciano M, Katz M, Ostrem J, Martin A, Starr P, Ziman N, Larson P -
Electrocorticography reveals beta desynchronization in the basal ganglia-cortical loop during rest tremor in Parkinson's disease.
Neurobiology of disease 2015 Qasim SE, de Hemptinne C, Swann NC, Miocinovic S, Ostrem JL, Starr PA -
Correspondence related to published material title "Deep brain stimulation may reduce the relative risk of clinically important worsening in early stage Parkinson's disease" by Hacker ML and colleague recently published electronically before print.
Parkinsonism & related disorders 2015 Ostrem JL, Starr PA -
Patterns of Cortical Synchronization in Isolated Dystonia Compared With Parkinson Disease.
JAMA neurology 2015 Miocinovic S, de Hemptinne C, Qasim S, Ostrem JL, Starr PA -
Response.
Journal of neurosurgery 2015 Kilbane C, Ramirez-Zamora A, Ryapolova-Webb E, Qasim S, Glass GA, Starr PA, Ostrem JL -
Clinical outcomes using ClearPoint interventional MRI for deep brain stimulation lead placement in Parkinson's disease.
Journal of neurosurgery 2015 Ostrem JL, Ziman N, Galifianakis NB, Starr PA, Luciano MS, Katz M, Racine CA, Martin AJ, Markun LC, Larson PS -
Motor System Interactions in the Beta Band Decrease during Loss of Consciousness.
Journal of cognitive neuroscience 2015 Swann NC, de Hemptinne C, Maher RB, Stapleton CA, Meng L, Gelb AW, Starr PA -
Task-related activity in sensorimotor cortex in Parkinson's disease and essential tremor: changes in beta and gamma bands.
Frontiers in human neuroscience 2015 Rowland NC, De Hemptinne C, Swann NC, Qasim S, Miocinovic S, Ostrem JL, Knight RT, Starr PA -
Elevated synchrony in Parkinson disease detected with electroencephalography.
Annals of neurology 2015 Swann NC, de Hemptinne C, Aron AR, Ostrem JL, Knight RT, Starr PA -
Intraoperative neurophysiology in deep brain surgery for psychogenic dystonia.
Annals of clinical and translational neurology 2015 Ramos VF, Pillai AS, Lungu C, Ostrem J, Starr P, Hallett M -
Therapeutic deep brain stimulation reduces cortical phase-amplitude coupling in Parkinson's disease.
Nature neuroscience 2015 de Hemptinne C, Swann NC, Ostrem JL, Ryapolova-Webb ES, San Luciano M, Galifianakis NB, Starr PA -
Differential effects of deep brain stimulation target on motor subtypes in Parkinson's disease.
Annals of neurology 2015 Katz M, Luciano MS, Carlson K, Luo P, Marks WJ, Larson PS, Starr PA, Follett KA, Weaver FM, Stern MB, Reda DJ, Ostrem JL -
Pallidal stimulation for Holmes tremor: clinical outcomes and single-unit recordings in 4 cases.
Journal of neurosurgery 2015 Kilbane C, Ramirez-Zamora A, Ryapolova-Webb E, Qasim S, Glass GA, Starr PA, Ostrem JL -
Combining cell transplants or gene therapy with deep brain stimulation for Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2014 Rowland NC, Starr PA, Larson PS, Ostrem JL, Marks WJ, Lim DA -
Interventional magnetic resonance imaging-guided cell transplantation into the brain with radially branched deployment.
Molecular therapy : the journal of the American Society of Gene Therapy 2014 Silvestrini MT, Yin D, Martin AJ, Coppes VG, Mann P, Larson PS, Starr PA, Zeng X, Gupta N, Panter SS, Desai TA, Lim DA -
Interventional MRI-guided deep brain stimulation in pediatric dystonia: first experience with the ClearPoint system.
Journal of neurosurgery. Pediatrics 2014 Starr PA, Markun LC, Larson PS, Volz MM, Martin AJ, Ostrem JL -
Effect of subthalamic nucleus deep brain stimulation on dual-task cognitive and motor performance in isolated dystonia.
Journal of neurology, neurosurgery, and psychiatry 2014 Mills KA, Markun LC, San Luciano M, Rizk R, Allen IE, Racine CA, Starr PA, Alberts JL, Ostrem JL -
Dr. Roy Bakay and the modern era of neurosurgical mentorship.
Stereotactic and functional neurosurgery 2014 Starr PA -
Brain shift during bur hole-based procedures using interventional MRI.
Journal of neurosurgery 2014 Ivan ME, Yarlagadda J, Saxena AP, Martin AJ, Starr PA, Sootsman WK, Larson PS -
Chronic cortical and electromyographic recordings from a fully implantable device: preclinical experience in a nonhuman primate.
Journal of neural engineering 2014 Ryapolova-Webb E, Afshar P, Stanslaski S, Denison T, de Hemptinne C, Bankiewicz K, Starr PA -
Effect of frequency on subthalamic nucleus deep brain stimulation in primary dystonia.
Parkinsonism & related disorders 2014 Ostrem JL, Markun LC, Glass GA, Racine CA, Volz MM, Heath SL, de Hemptinne C, Starr PA -
Three-dimensional accuracy of ECOG strip electrode localization using coregistration of preoperative MRI and intraoperative fluoroscopy.
Stereotactic and functional neurosurgery 2013 Rowland NC, Miller KJ, Starr PA -
Neuromodulation for dystonia: target and patient selection.
Neurosurgery clinics of North America 2013 Mills KA, Starr PA, Ostrem JL -
Commentary on "Adaptive deep brain stimulation in advanced Parkinson disease".
Annals of neurology 2013 Starr PA, Ostrem JL -
Predictive factors of outcome in primary cervical dystonia following pallidal deep brain stimulation.
Movement disorders : official journal of the Movement Disorder Society 2013 Witt JL, Moro E, Ash RS, Hamani C, Starr PA, Lozano AM, Hodaie M, Poon YY, Markun LC, Ostrem JL -
Radially branched deployment for more efficient cell transplantation at the scale of the human brain.
Stereotactic and functional neurosurgery 2013 Silvestrini MT, Yin D, Coppes VG, Mann P, Martin AJ, Larson PS, Starr PA, Gupta N, Panter SS, Desai TA, Lim DA -
Deep brain stimulation for other tremors, myoclonus, and chorea.
Handbook of clinical neurology 2013 Starr PA -
Clinical outcomes of PD patients having bilateral STN DBS using high-field interventional MR-imaging for lead placement.
Clinical neurology and neurosurgery 2012 Ostrem JL, Galifianakis NB, Markun LC, Grace JK, Martin AJ, Starr PA, Larson PS -
Weight change after globus pallidus internus or subthalamic nucleus deep brain stimulation in Parkinson's disease and dystonia.
Stereotactic and functional neurosurgery 2012 Mills KA, Scherzer R, Starr PA, Ostrem JL -
Shorter disease duration correlates with improved long-term deep brain stimulation outcomes in young-onset DYT1 dystonia.
Neurosurgery 2012 Markun LC, Starr PA, Air EL, Marks WJ, Volz MM, Ostrem JL -
Randomized trial of deep brain stimulation for Parkinson disease: thirty-six-month outcomes.
Neurology 2012 Weaver FM, Follett KA, Stern M, Luo P, Harris CL, Hur K, Marks WJ, Rothlind J, Sagher O, Moy C, Pahwa R, Burchiel K, Hogarth P, Lai EC, Duda JE, Holloway K, Samii A, Horn S, Bronstein JM, Stoner G, … -
Acute effects of thalamic deep brain stimulation and thalamotomy on sensorimotor cortex local field potentials in essential tremor.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2012 Air EL, Ryapolova-Webb E, de Hemptinne C, Ostrem JL, Galifianakis NB, Larson PS, Chang EF, Starr PA -
Paroxysmal sneezing after hypothalamic deep brain stimulation for cluster headache.
Cephalalgia : an international journal of headache 2012 Maniyar FH, Starr P, Goadsby PJ -
Long-term evaluation of a phase 1 study of AADC gene therapy for Parkinson's disease.
Human gene therapy 2012 Mittermeyer G, Christine CW, Rosenbluth KH, Baker SL, Starr P, Larson P, Kaplan PL, Forsayeth J, Aminoff MJ, Bankiewicz KS -
An optimized system for interventional magnetic resonance imaging-guided stereotactic surgery: preliminary evaluation of targeting accuracy.
Neurosurgery 2012 Larson PS, Starr PA, Bates G, Tansey L, Richardson RM, Martin AJ -
Intraoperative neurophysiology in DBS for dystonia.
Movement disorders : official journal of the Movement Disorder Society 2011 Vitek JL, Delong MR, Starr PA, Hariz MI, Metman LV -
Stereotactic techniques and perioperative management of DBS in dystonia.
Movement disorders : official journal of the Movement Disorder Society 2011 Starr PA, Bejjani P, Lozano AM, Metman LV, Hariz MI -
Novel platform for MRI-guided convection-enhanced delivery of therapeutics: preclinical validation in nonhuman primate brain.
Stereotactic and functional neurosurgery 2011 Richardson RM, Kells AP, Martin AJ, Larson PS, Starr PA, Piferi PG, Bates G, Tansey L, Rosenbluth KH, Bringas JR, Berger MS, Bankiewicz KS -
Factors predicting protracted improvement after pallidal DBS for primary dystonia: the role of age and disease duration.
Journal of neurology 2011 Isaias IU, Volkmann J, Kupsch A, Burgunder JM, Ostrem JL, Alterman RL, Mehdorn HM, Schönecker T, Krauss JK, Starr P, Reese R, Kühn AA, Schüpbach WM, Tagliati M -
Interventional MRI-guided putaminal delivery of AAV2-GDNF for a planned clinical trial in Parkinson's disease.
Molecular therapy : the journal of the American Society of Gene Therapy 2011 Richardson RM, Kells AP, Rosenbluth KH, Salegio EA, Fiandaca MS, Larson PS, Starr PA, Martin AJ, Lonser RR, Federoff HJ, Forsayeth JR, Bankiewicz KS -
Incidence and management of venous air embolisms during awake deep brain stimulation surgery in a large clinical series.
Stereotactic and functional neurosurgery 2011 Chang EF, Cheng JS, Richardson RM, Lee C, Starr PA, Larson PS -
Human/nonhuman primate AC-PC ratio--considerations for translational brain measurements.
Journal of neuroscience methods 2010 Fiandaca MS, Salegio EA, Yin D, Richardson RM, Valles FE, Larson PS, Starr PA, Lonser RR, Bankiewicz KS -
Qualitative imaging of adeno-associated virus serotype 2-human aromatic L-amino acid decarboxylase gene therapy in a phase I study for the treatment of Parkinson disease.
Neurosurgery 2010 Valles F, Fiandaca MS, Eberling JL, Starr PA, Larson PS, Christine CW, Forsayeth J, Richardson RM, Su X, Aminoff MJ, Bankiewicz KS -
Long-term follow-up of pallidal deep brain stimulation in two cases of Huntington's disease.
Journal of neurology, neurosurgery, and psychiatry 2010 Kang GA, Heath S, Rothlind J, Starr PA -
Gene delivery of AAV2-neurturin for Parkinson's disease: a double-blind, randomised, controlled trial.
The Lancet. Neurology 2010 Marks WJ, Bartus RT, Siffert J, Davis CS, Lozano A, Boulis N, Vitek J, Stacy M, Turner D, Verhagen L, Bakay R, Watts R, Guthrie B, Jankovic J, Simpson R, Tagliati M, Alterman R, Stern M, Baltuch G, … -
Pallidal neuronal discharge in Parkinson's disease following intraputamenal fetal mesencephalic allograft.
Journal of neurology, neurosurgery, and psychiatry 2010 Richardson RM, Freed CR, Shimamoto SA, Starr PA -
Bursts and oscillations as independent properties of neural activity in the parkinsonian globus pallidus internus.
Neurobiology of disease 2010 Chan V, Starr PA, Turner RS -
Long-term benefit sustained after bilateral pallidal deep brain stimulation in patients with refractory tardive dystonia.
Stereotactic and functional neurosurgery 2010 Chang EF, Schrock LE, Starr PA, Ostrem JL -
Spinal deformity and Parkinson disease: a treatment algorithm.
Neurosurgical focus 2010 Upadhyaya CD, Starr PA, Mummaneni PV -
Pedunculopontine nucleus deep brain stimulation in a patient with primary progressive freezing gait disorder.
Stereotactic and functional neurosurgery 2009 Ostrem JL, Christine CW, Glass GA, Schrock LE, Starr PA -
Safety and tolerability of putaminal AADC gene therapy for Parkinson disease.
Neurology 2009 Christine CW, Starr PA, Larson PS, Eberling JL, Jagust WJ, Hawkins RA, VanBrocklin HF, Wright JF, Bankiewicz KS, Aminoff MJ -
Surgical repositioning of misplaced subthalamic electrodes in Parkinson's disease: location of effective and ineffective leads.
Stereotactic and functional neurosurgery 2009 Richardson RM, Ostrem JL, Starr PA -
Deep brain stimulation for medically intractable cluster headache.
Neurobiology of disease 2009 Sillay KA, Sani S, Starr PA -
Implantation of deep brain stimulator electrodes using interventional MRI.
Neurosurgery clinics of North America 2009 Starr PA, Martin AJ, Larson PS -
Software requirements for interventional MR in restorative and functional neurosurgery.
Neurosurgery clinics of North America 2009 Martin AJ, Starr PA, Larson PS -
Microelectrode recording in the posterior hypothalamic region in humans.
Neurosurgery 2009 Sani S, Shimamoto S, Turner RS, Levesque N, Starr PA -
Induction of bradykinesia with pallidal deep brain stimulation in patients with cranial-cervical dystonia.
Stereotactic and functional neurosurgery 2009 Berman BD, Starr PA, Marks WJ, Ostrem JL -
Interventional magnetic resonance guidance of deep brain stimulator implantation for Parkinson disease.
Topics in magnetic resonance imaging : TMRI 2009 Martin AJ, Larson PS, Ostrem JL, Starr PA -
Single unit "pauser" characteristics of the globus pallidus pars externa distinguish primary dystonia from secondary dystonia and Parkinson's disease.
Experimental neurology 2008 Sani S, Ostrem JL, Shimamoto S, Levesque N, Starr PA -
DBS and dopamine. Comment on "Does dopamine still have a leading role in advanced Parkinson's disease after subthalamic stimulation?" (Stereotact Funct Neurosurg 2008;86: 184-186).
Stereotactic and functional neurosurgery 2008 Starr PA -
Results from a phase I safety trial of hAADC gene therapy for Parkinson disease.
Neurology 2008 Eberling JL, Jagust WJ, Christine CW, Starr P, Larson P, Bankiewicz KS, Aminoff MJ -
Safety and tolerability of intraputaminal delivery of CERE-120 (adeno-associated virus serotype 2-neurturin) to patients with idiopathic Parkinson's disease: an open-label, phase I trial.
The Lancet. Neurology 2008 Marks WJ, Ostrem JL, Verhagen L, Starr PA, Larson PS, Bakay RA, Taylor R, Cahn-Weiner DA, Stoessl AJ, Olanow CW, Bartus RT -
Minimally invasive precision brain access using prospective stereotaxy and a trajectory guide.
Journal of magnetic resonance imaging : JMRI 2008 Martin AJ, Hall WA, Roark C, Starr PA, Larson PS, Truwit CL -
Treatment of dystonia with deep brain stimulation.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2008 Ostrem JL, Starr PA -
Thalamic deep brain stimulation for essential tremor: relation of lead location to outcome.
Neurosurgery 2008 Papavassiliou E, Rau G, Heath S, Abosch A, Barbaro NM, Larson PS, Lamborn K, Starr PA -
Magnetic resonance imaging of implanted deep brain stimulators: experience in a large series.
Stereotactic and functional neurosurgery 2007 Larson PS, Richardson RM, Starr PA, Martin AJ -
Clinical problem solving: finding the target.
Neurosurgery 2007 Deogaonkar M, Walter BL, Boulis N, Starr P -
First case of X-linked dystonia-parkinsonism ("Lubag") to demonstrate a response to bilateral pallidal stimulation.
Movement disorders : official journal of the Movement Disorder Society 2007 Evidente VG, Lyons MK, Wheeler M, Hillman R, Helepolelei L, Beynen F, Nolte D, Müller U, Starr PA -
Chronic stimulation of the posterior hypothalamic region for cluster headache: technique and 1-year results in four patients.
Journal of neurosurgery 2007 Starr PA, Barbaro NM, Raskin NH, Ostrem JL -
Effects of unilateral subthalamic and pallidal deep brain stimulation on fine motor functions in Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2007 Nakamura K, Christine CW, Starr PA, Marks WJ -
Multiple target deep brain stimulation for multiple sclerosis related and poststroke Holmes' tremor.
Stereotactic and functional neurosurgery 2007 Lim DA, Khandhar SM, Heath S, Ostrem JL, Ringel N, Starr P -
Neuropsychological performance following staged bilateral pallidal or subthalamic nucleus deep brain stimulation for Parkinson's disease.
Journal of the International Neuropsychological Society : JINS 2007 Rothlind JC, Cockshott RW, Starr PA, Marks WJ -
Placement of deep brain stimulator electrodes using real-time high-field interventional magnetic resonance imaging.
Magnetic resonance in medicine 2005 Martin AJ, Larson PS, Ostrem JL, Keith Sootsman W, Talke P, Weber OM, Levesque N, Myers J, Starr PA -
Frameless stereotaxy using bone fiducial markers for deep brain stimulation.
Journal of neurosurgery 2005 Holloway KL, Gaede SE, Starr PA, Rosenow JM, Ramakrishnan V, Henderson JM -
Risk factors for hemorrhage during microelectrode-guided deep brain stimulator implantation for movement disorders.
Neurosurgery 2005 Binder DK, Rau GM, Starr PA -
Surgery for Parkinson's disease: integration of neurology and neurosurgery.
Clinical neurosurgery 2005 Starr PA -
Microelectrode-guided implantation of deep brain stimulators into the globus pallidus internus for dystonia: techniques, electrode locations, and outcomes.
Neurosurgical focus 2004 Starr PA, Turner RS, Rau G, Lindsey N, Heath S, Volz M, Ostrem JL, Marks WJ -
Thalamic deep brain stimulation for essential tremor: relation of lead location to outcome.
Neurosurgery 2004 Papavassiliou E, Rau G, Heath S, Abosch A, Barbaro NM, Larson PS, Lamborn K, Starr PA -
Surgery of the subthalamic nucleus: use of movement-related neuronal activity for surgical navigation.
Neurosurgery 2003 Starr PA, Theodosopoulos PV, Turner R -
Hemorrhagic complications of microelectrode-guided deep brain stimulation.
Stereotactic and functional neurosurgery 2003 Binder DK, Rau G, Starr PA -
Placement of deep brain stimulators into the subthalamic nucleus or Globus pallidus internus: technical approach.
Stereotactic and functional neurosurgery 2002 Starr PA -
Electrophysiological localization of the substantia nigra in the parkinsonian nonhuman primate.
Journal of neurosurgery 2000 Starr PA, Subramanian T, Bakay RA, Wichmann T -
Deep brain stimulation for advanced Parkinson's disease.
AORN journal 2000 Byrd DL, Marks WJ, Starr PA -
A high-resolution fast spin-echo inversion-recovery sequence for preoperative localization of the internal globus pallidus.
AJNR. American journal of neuroradiology 2000 Reich CA, Hudgins PA, Sheppard SK, Starr PA, Bakay RA -
Porcine xenografts in Parkinson's disease and Huntington's disease patients: preliminary results.
Cell transplantation 2000 Fink JS, Schumacher JM, Ellias SL, Palmer EP, Saint-Hilaire M, Shannon K, Penn R, Starr P, VanHorne C, Kott HS, Dempsey PK, Fischman AJ, Raineri R, Manhart C, Dinsmore J, Isacson O -
Comparison of MPTP-induced changes in spontaneous neuronal discharge in the internal pallidal segment and in the substantia nigra pars reticulata in primates.
Experimental brain research 1999 Wichmann T, Bergman H, Starr PA, Subramanian T, Watts RL, DeLong MR -
Magnetic resonance imaging-based stereotactic localization of the globus pallidus and subthalamic nucleus.
Neurosurgery 1999 Starr PA, Vitek JL, DeLong M, Bakay RA -
Intranigral transplantation of fetal substantia nigra allograft in the hemiparkinsonian rhesus monkey.
Cell transplantation 1999 Starr PA, Wichmann T, van Horne C, Bakay RA -
Ablative surgery and deep brain stimulation for Parkinson's disease.
Neurosurgery 1998 Starr PA, Vitek JL, Bakay RA -
The homeless and the public household.
The New England journal of medicine 1998 Starr P -
Microelectrode-guided pallidotomy: technical approach and its application in medically intractable Parkinson's disease.
Journal of neurosurgery 1998 Vitek JL, Bakay RA, Hashimoto T, Kaneoke Y, Mewes K, Zhang JY, Rye D, Starr P, Baron M, Turner R, DeLong MR -
Pre- and postoperative MR evaluation of stereotactic pallidotomy.
AJNR. American journal of neuroradiology 1998 Cohn MC, Hudgins PA, Sheppard SK, Starr PA, Bakay RA -
Deep brain stimulation for movement disorders.
Neurosurgery clinics of North America 1998 Starr PA, Vitek JL, Bakay RA -
Posterior ventral pallidotomy: techniques and theoretical considerations.
Clinical neurosurgery 1997 Bakay RA, Starr PA, Vitek JL, DeLong MR -
Surgery of the Soul's cistern.
Neurosurgery 1996 Apuzzo ML, Stieg PE, Starr P, Schwartz RB, Folkerth RD -
Long-term persistence of defective HSV-1 vectors in the rat brain is demonstrated by reactivation of vector gene expression.
Gene therapy 1996 Starr PA, Lim F, Grant FD, Trask L, Lang P, Yu L, Geller AI -
The framework of health care reform.
The New England journal of medicine 1993 Starr P -
Effects of calcitonin gene-related peptide and efferent nerve stimulation on afferent transmission in the lateral line organ.
Journal of neurophysiology 1991 Sewell WF, Starr PA -
Hypercholesterolemia in school children: a preliminary report.
American journal of clinical pathology 1971 Starr P -
Later results of 131-I treatment of hyperthyroidism in 73 children and adolescents: 1967 followup.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1969 Starr P, Jaffe HL, Oettinger L -
LATE RESULTS OF I-131 TREATMENT OF HYPERTHYROIDISM IN SEVENTY-THREE CHILDREN AND ADOLESCENTS.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1964 STARR P, JAFFE HL, OETTINGER L