Philip Rosenthal, MD
Professor
Pediatrics
School of Medicine
Dr. Rosenthal is the Director of Pediatric Hepatology, Medical Director of the Pediatric Liver Transplant Program and a Professor of Pediatrics and Surgery at the University of California, San Francisco (UCSF). He is board certified in Pediatrics and Pediatric Gastroenterology and has a Certificate of Added Qualification in Transplant Hepatology.
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Dr. Rosenthal completed his medical training at Downstate Medical Center and the Albert Einstein Medical Center in New York. He then completed a fellowship in pediatric gastroenterology at UCSF. He joined the UCSF faculty in 1995 after serving as Professor of Pediatrics at University of California, Los Angeles (UCLA).
Dr. Rosenthal is a prolific author and a recipient of a number of professional honors and awards and is committed to clinical service, research and education. He has published numerous research articles on hepatitis. Currently, Dr. Rosenthal is pursuing research on the pharmaceutical treatment of hepatitis B and C, genetics and immunology of biliary disease, use of bioartificial liver support utilizing porcine hepatocytes for patients with fulminant liver failure, as well as researching the quality of life following liver transplantation in children.
Dr. Rosenthal’s professional services to the public include television, newspaper and radio interviews on various topics such as hepatitis A, B, and C, and liver transplants for local, national and international audiences. He is consultant to organizations such as the American Liver Foundation, Parents of Kids with Infectious Disease, the Centers for Disease Control and Prevention (CDC), and the National Institute of Health (NIH)
Awards
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- Murray Davidson Award, American Academy of Pediatrics, 2013
- Chancellor's Award for Public Service, UCSF, 2002
Education & Training
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- Diversity, Equity, and Inclusion Champion Training University of California 02/2021
- M.D. School of Medicine SUNY Brooklyn 1975
Interests
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- hepatitis
- liver transplant
- hepatology
- NAFLD
- NASH
Websites
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- Clinical Profile at UCSF Benioff Children's Hospital (ucsfbenioffchildrens.org)
Grants and Projects
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Publications (716)
Top publication keywords:
UgandaBiliary AtresiaDrug ResistanceQuinolinesMalariaCholestasisParasitemiaArtemisininsCysteine EndopeptidasesAntimalarialsMalaria, FalciparumAlagille SyndromeFluorenesPlasmodium falciparumProtozoan Proteins
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Structure-Activity Relationship Study of Antimalarial Asparagine-Derived Proteasome Inhibitors.
ACS omega 2026 Zhang H, Li D, Hsu HC, Vishwanatha A, Zhan W, Yukawa T, Visone J, Imaeda T, Okamoto R, Fajtova P, Hara R, Kawasaki M, Sato K, Michino M, Garg S, Kreutzfeld O, Tumwebaze PK, Orena S, Okitwi M, Aso K, … -
Bradykinin contributes to vasogenic edema in murine experimental cerebral malaria.
The Journal of clinical investigation 2026 de Sa Pinheiro AS, Teixeira DE, Silva-Aguiar RP, Shim YJ, Merkulova AA, Silbak S, Skomorovska-Prokvolit Y, Midem D, Ogolla S, Burckhardt BB, Gangnus T, Scharfstein J, Caruso-Neves C, McCarty OJ, … -
The Proposed United States Office of Management and Budget Rule for Managing Biomedical Research Grants and Cooperative Agreements Needs to Change.
The American journal of tropical medicine and hygiene 2026 Rosenthal PJ, Nishi JB, Ko AI, Fidock DA, Taylor TE -
Malaria prevalence and molecular markers of Plasmodium falciparum antimalarial drug resistance among mobile populations in malaria-endemic countries: A systematic review and meta-analysis.
Research square 2026 Mwesigwa A, Fatima D, Nsengimaana B, Arineitwe E, Kinengyere AA, Mpimbaza A, Byakika-Kibwika P, Mbulaiteye SM, Rosenthal PJ, Nsobya SL -
Slowing the spread of treatment failure to artemisinin-based combination therapies in Uganda.
Nature communications 2026 Nguyen TD, Zupko RJ, Conrad MD, Rukundo GB, Farinha CC, Asua VD, Tran KT, Grace DM, Rosenthal PJ, Agaba BB, Kamya MR, Opigo J, Boni MF
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Recurrent Plasmodium falciparum Parasitemia and Drug Resistance Mutations During Intermittent Preventive Treatment of Malaria in Pregnancy in Uganda.
The Journal of infectious diseases 2026 Kizza J, Katairo T, Kakuru A, Nsengimaana B, Esilu T, Wiringilimaana I, Semakuba FD, Gerlovina I, Hathaway N, Briggs J, Tukwasibwe S, Kiwuwa SM, Kamya MR, Nankabirwa JI, Dorsey G, Rosenthal PJ -
Sustained high prevalence of multiple antimalarial drug resistance markers in Uganda in 2023-2024.
Antimicrobial agents and chemotherapy 2026 Katairo T, Asua V, Semakuba FD, Nsengimaana B, Kiyaga S, Hathaway N, Murie K, Tukwasibwe S, Wiringilimaana I, Nakasaanyaa J, Mwubaha C, Achom KB, Esilu TE, Ayitewalah A, Mbabazi M, Kabbale KD, Mulondo… -
Ebola outbreak caused by Bundibugyo virus: challenges and priorities for epidemic preparedness and response.
Lancet (London, England) 2026 Nachega JB, Mbala-Kingebeni P, Mulangu S, Ndembi N, Preiser W, Skinner D, Sam-Agudu NA, Ntoumi F, Tegally H, Baxter C, Oliveira T, Bosa HK, Kaleebu P, Kallay O, Uthman OA, Mills EJ, Rosenthal PJ, … -
Intravenous Artesunate in Artemisinin-Resistant Severe Malaria in Uganda.
The New England journal of medicine 2026 Maitland K, Okao M, Conrad MD, Etwop T, Akite M, Oguda E, Alaroker F, Aromut D, Muhindo R, Uyoga S, Olupot-Olupot P, Mogaka C, Connon R, Katairo T, Okitwi M, Briggs J, Gibb DM, Day NPJ, White NJ, … -
Target product profiles of laboratory and data analytical frameworks for genotyping to monitor antimalarial efficacy.
PLOS global public health 2026 Plucinski MM, Wesolowski A, Gerlovina I, Taylor AR, Briggs J, Aranda-Díaz A, Golumbeanu M, Bajic M, Bailey JA, Barratt JLN, Buckee C, Deme AB, Felger I, Ghansah A, Hastings I, Kattenberg JH, Mayor A, … -
Furoxan derivatives with antimalarial activity that disrupt P. falciparum endoplasmic reticulum calcium homeostasis.
International journal for parasitology. Drugs and drug resistance 2026 da Costa Clementino L, Bartlett PJ, Fernandes GFS, Honorio RI, Legac J, Dos Santos JL, Rosenthal PJ, Garcia CRS, Thomas AP, Graminha MAS -
A Plasmodium falciparum PX1 haplotype is associated with reduced susceptibility to artemisinin and lumefantrine.
bioRxiv : the preprint server for biology 2026 Bower-Lepts C, Jangra A, Kanatani S, Tripathi A, Mlambo G, McCotter-González A, Romano L, Orena S, Okitwi M, Niaré K, Rosenthal PJ, Conrad M, Sinnis P, Mok S -
Development and validation of UHPLC-MS/MS methods for determination of piperaquine in quantitative dried blood samples and microvolume plasma samples.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2026 He MS, He S, Roh M, Kakuru A, Jagannathan P, Dorsey G, Rosenthal P, Aweeka F, Huang L -
Impact of intermittent preventive treatment for malaria in pregnancy with sulfadoxine-pyrimethamine, dihydroartemisinin-piperaquine, and their combination on infant outcomes: A randomized controlled trial.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2026 Nankabirwa JI, Kakuru A, Nguyen AT, Roh ME, Aguti M, Adrama H, Kizza J, Olwoch P, Camanag K, Benjamin-Chung J, Rosenthal PJ, Kamya MR, Dorsey G, Jagannathan P -
Potent acridone antimalarial against all three life stages of Plasmodium.
Nature communications 2026 Kancharla P, Dodean RA, Li Y, Zhang X, Kelly S, Charlton J, Binauhan AJ, Navarrete K, Garcia L, Mu J, Lu J, Caridha D, Madejczyk MS, Jin X, Dennis WE, Kudyba K, McEnearney S, Lee PJ, Blount C, DeLuca … -
Natural History and the Burden of Malaria During the First Year of Life in the High-Transmission Setting of Uganda.
The American journal of tropical medicine and hygiene 2026 Aguti M, Nankabirwa JI, Kizza J, Kakuru A, Ssemukuye T, Adrama H, Olwoch P, Opira B, Odongo B, Camanag K, Nakalembe M, Clark T, Rosenthal PJ, Dorsey G, Jaganathan P, Kamya MR -
CD8 TRM-like T cells expressing perforin and IFN-γ define a pediatric activated T-cell acute liver failure endotype.
Hepatology communications 2026 Diamond T, Chapin CA, Diorio CJ, McCuaig S, Lau M, Chu N, Gibson NM, Kreiger PA, Horslen S, Loomes KM, Banc-Husu AM, Chu J, Jensen MK, Leung DH, Narang A, Carter BA, Elisofon S, Fischer R, Lobritto SJ… -
Sustained High Prevalence of Multiple Antimalarial Drug Resistance Markers in Uganda in 2023-24.
medRxiv : the preprint server for health sciences 2026 Katairo T, Asua V, Semakuba FD, Nsengimaana B, Kiyaga S, Hathaway N, Murie K, Tukwasibwe S, Wiringilimaana I, Nakasaanya J, Mwubaha C, Achom KB, Esilu TE, Ayitewala A, Mbabazi M, Kabbale KD, Mulondo J… -
Demographic Factors and Biliary Atresia: A Childhood Liver Disease Research Network Study.
Pediatrics 2026 Kastenberg ZJ, Beil CA, Henn L, Alonso EM, Hsu EK, Wang K, Ng VL, Gupta NA, Magee JC, Merion RM, Horslen S, Karpen SJ, Kohli R, Loomes K, Miethke A, Tolliver KM, Rosenthal P, Harpavat S, Sokol RJ, … -
Accuracy of Plasmodium falciparum genetic data for estimating parasite prevalence and malaria incidence in Uganda.
Malaria journal 2026 Kiyaga S, Mbabazi M, Katairo T, Kabbale KD, Asua V, Nsengimaana B, Wiringilimaana I, Semakuba FD, Mwubaha C, Nakasaanya J, Watyekele E, Ayitewala A, Tukwasibwe S, Mulondo J, Nsobya SL, Agaba B, … -
Defining the Society of Pediatric Liver Transplantation (SPLIT) research agenda: A Delphi consensus project.
Hepatology communications 2026 Wadhwani SI, Spector PR, Feldman AG, Furuya KN, Hartjes K, Jarasvaraparn C, Kelly B, Lerret SM, Mysore K, Pawaria A, Rosenthal P, Shui A, Slowik V, Taylor S, Vittorio J, Valentino PL, Society of … -
Imported malaria predominates in near-elimination settings in Southwestern Uganda.
medRxiv : the preprint server for health sciences 2026 Mbabazi M, Kiyaga S, Katairo T, Kabbale KD, Asua V, Kagurusi BA, Wiringilimaana I, Nsengimaana B, Semakuba FD, Nakasaanya J, Ayitewala A, Watyekele E, Nabende I, Kayondo TM, Arinaitwe E, Mulondo J, … -
Impact of intermittent preventive treatment of malaria in pregnancy with sulfadoxine-pyrimethamine on sexually transmitted and reproductive tract infections: results from a randomized trial in Uganda.
International journal of epidemiology 2026 Adrama H, Dela Cruz EJ, Ozarslan N, Kakuru A, Odongo B, Gaw SL, Benjamin-Chung J, Kizza J, Aguti M, Ategeka J, Olwoch P, Nakalembe M, Opira B, Clark TD, Kamya MR, Rosenthal PJ, Dorsey G, Roh ME -
Maternal and household risk factors for malaria in pregnancy and low birthweight: a prospective cohort study from Uganda.
Malaria journal 2025 Aguti M, Kizza J, Kakuru A, Nakalembe M, Nankabirwa JI, Gaw SL, Opira B, Ssemukuye T, Ozarslan N, Ranjit A, Dela Cruz E, Clark TD, Roh ME, Jagannathan P, Rosenthal PJ, Adrama H, Olwoch P, Mayende J, … -
Disentangling the roles of different vector species during a malaria resurgence in Eastern Uganda.
PLOS global public health 2025 McClure M, Oruni A, Arinaitwe E, Musiime A, Kyagamba P, Otto G, Adiga J, Rwatooro JA, Kilama M, Krezanoski P, Briggs J, Rosenthal PJ, Nankabirwa JI, Kamya MR, Dorsey G, Greenhouse B, Rodriguez-… -
Accuracy of Plasmodium falciparum genetic data for estimating parasite prevalence and malaria incidence in Uganda.
Research square 2025 Kiyaga S, Mbabazi M, Katairo T, Kabbale KD, Asua V, Nsengimaana B, Wiringilimaana I, Semakuba FD, Mwubaha C, Nakasaanya J, Watyekele E, Ayitewala A, Tukwasibwe S, Mulondo J, Nsobya SL, Agaba B, … -
Secondary prophylaxis of variceal hemorrhage in biliary atresia-Analysis of prospective multicenter studies.
Journal of pediatric gastroenterology and nutrition 2025 Bass LM, Hawthorne K, Magee JC, Shneider BL, Childhood Liver Disease Research Network (ChiLDReN) -
Optimization of Prodiginines as Single-Dose Curative Antimalarials.
Journal of medicinal chemistry 2025 Kumar A, Li Y, Zhang X, Gaddam M, Caridha D, Madejczyk MS, Jin X, Dennis WE, Chetree R, Blount C, DeLuca J, Vuong C, Kudyba K, Roncal N, Ashraf K, Lee PJ, Pannone K, Leed S, Dinh HT, Mdaki K, … -
Is Seasonal Malaria Chemoprevention with Sulfadoxine-Pyrimethamine/Amodiaquine Appropriate in East Africa?
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2025 Rosenthal PJ -
Recurrent Plasmodium falciparum parasitemia and drug resistance mutations during intermittent preventive treatment of malaria in pregnancy in Uganda.
medRxiv : the preprint server for health sciences 2025 Kizza J, Katairo T, Kakuru A, Nsengimaana B, Esilu T, Wiringilimaana I, Semakuba FD, Gerlovina I, Hathaway N, Briggs J, Tukwasibwe S, Kiwuwa SM, Kamya MR, Nankabirwa JI, Dorsey G, Rosenthal PJ -
Characterization of β-Carboline Derivatives Reveals a High Barrier to Resistance and Potent Activity against Ring-Stage and DHA-Induced Dormant Plasmodium falciparum.
ACS infectious diseases 2025 Haney RS, Butler JH, Wardlaw LA, Merino EF, Mendiola V, Cooper CA, Mathew J, Tumwebaze PK, Rosenthal PJ, Cooper RA, Kyle DE, Rizopoulos Z, Baud D, Brand S, Totrov M, Carlier PR, Cassera MB -
Improving antimalarial therapeutic efficacy studies.
The Lancet. Infectious diseases 2025 Rosenthal PJ -
Plasma proteome correlations with liver stiffness in pediatric cholestasis implicate epithelial to mesenchymal transition.
Hepatology communications 2025 Shneider BL, Kanchi RS, Grimm SL, Devaraj S, Emamaullee J, Schraw J, Lupo PJ, Bezerra JA, Loomes KM, Magee JC, Sokol RJ, Wang KS, Kriegermeier A, Hsu E, Molleston JP, Rosenthal P, Kohli R, Karpen SJ, … -
Dihydroartemisinin-piperaquine plus sulfadoxine-pyrimethamine versus either drug alone for intermittent preventive treatment of malaria in pregnancy: A double-blind, randomized, controlled phase 3 trial from Uganda.
PLoS medicine 2025 Kakuru A, Kizza J, Aguti M, Adrama H, Ategeka J, Olwoch P, Nakalembe M, Nankabirwa JI, Opira B, Ozarslan N, Ranjit A, Dela Cruz E, Clark TD, Roh ME, Gaw SL, Jagannathan P, Rosenthal PJ, Kamya MR, … -
Maternal and household risk factors for malaria in pregnancy and low birthweight: a prospective cohort study from Uganda.
Research square 2025 Aguti M, Kizza J, Kakuru A, Nakalembe M, Nankabirwa JI, Gaw SL, Opira B, Ssemukuye T, Ozarslan N, Ranjit A, Cruz E, Clark TD, Roh ME, Jagannathan P, Rosenthal PJ, Adrama H, Olwoch P, Mayende J, Odongo… -
Prospective Multicenter Longitudinal Measurement of Liver Stiffness in School-Age Children With Cholestatic Liver Disease.
Gastro hep advances 2025 Shneider BL, Goodrich NP, Ye W, Molleston JP, Leung DH, Sokol RJ, Cavallo L, Wang K, Valentino PL, Teckman JH, Squires JE, Sundaram SS, Rosenthal P, Romero R, Miethke AG, Loomes KM, Kohli R, Karpen SJ… -
Remoscope: a label-free imaging cytometer for malaria diagnostics.
Transactions of the Royal Society of Tropical Medicine and Hygiene 2025 Lebel PM, Jeyakumar I, Khoo MWL, Emorut J, Charlton C, Saxena A, Jacobsen A, Huynh E, Wu W, Courville G, Fu PC, Raghavan M, Puccinelli R, Olwoch P, Dorsey G, Rosenthal PJ, DeRisi J, Gomez-Sjoberg R -
Efficacies of artemether-lumefantrine, artesunate-amodiaquine, dihydroartemisinin-piperaquine, and artesunate-pyronaridine for the treatment of uncomplicated Plasmodium falciparum malaria in children aged 6 months to 10 years in Uganda: a randomised, open-label, phase 4 clinical trial.
The Lancet. Infectious diseases 2025 Kamya MR, Nankabirwa JI, Ebong C, Asua V, Kiggundu M, Orena S, Okitwi M, Tukwasibwe S, Agaba B, Kyabayinze D, Opigo J, Rutazana D, Binagwa B, Mugwanya E, Babirye S, Sebikaari G, Condo PM, Appiah G, … -
Weight gain in infancy and metabolic dysfunction-associated steatotic liver disease (MASLD) in a prospective birth cohort of Latino children.
Maternal health, neonatology and perinatology 2025 Maxwell SL, Price JC, Perito ER, Rosenthal P, Wojcicki JM -
Relating household entomological measures to individual malaria risk.
Malaria journal 2025 McClure M, Arinaitwe E, Kamya MR, Rosenthal PJ, Nankabirwa J, Kilama M, Musiime A, Dorsey G, Greenhouse B, Rodriguez-Barraquer I -
Changes in susceptibility of Plasmodium falciparum to antimalarial drugs in Uganda over time: 2019-2024.
Nature communications 2025 Okitwi M, Orena S, Tumwebaze PK, Katairo T, Taremwa Y, Byaruhanga O, Tukwasibwe S, Nsobya SL, Legac J, Bailey JA, Cooper RA, Conrad MD, Rosenthal PJ -
Identifying a next-generation antimalarial trioxolane in a landscape of artemisinin partial resistance.
Science advances 2025 Klope MT, Talukder P, Blank BR, Chelebieva S, Chen J, Fontaine SD, Gonciarz RL, Jaishankar P, Lee GJ, Legac J, Mathur V, Narayan A, Okitwi M, Orena S, Settineri NS, Tapia JA, Taremwa Y, Tumwebaze PK, … -
Regulatory KIR+CD8+ T cells are elevated during human pregnancy.
Science translational medicine 2025 Li J, Wang X, Lackner AI, Narasimhan P, Li L, Mallajosyula V, Johnson MM, Höbler AL, Kirosingh AS, Braun AE, Nankya F, Musinguzi K, Kakuru A, Kamya M, Rosenthal PJ, Dorsey G, Jagannathan P, Angelo M, … -
Biannual Mass Azithromycin Distributions for Preschool Children and Malaria Parasitemia: A Secondary Analysis of the MORDOR Cluster Randomized Trial.
JAMA network open 2025 Arzika AM, Abdou A, Maliki R, Lebas E, Cook C, Vanderschelden B, O'Brien KS, Cotter SY, Varnado NE, Callahan EK, Bailey RL, West SK, Rosenthal PJ, Porco TC, Lietman TM, Keenan JD, MORDOR-Niger Study … -
Plasmodiumfalciparum protein kinase 6 and hemozoin formation are inhibited by a type II human kinase inhibitor exhibiting antimalarial activity.
Cell chemical biology 2025 Nardella F, Jiang T, Wang L, Bohmer MJ, Chakraborty S, Okombo J, Calla J, Silva TM, Pazicky S, Che J, Jeon J, Vincent E, Boonyalai N, Coyle R, Buchanan MJ, Schaefer S, Chen D, Khan A, Mayville E, De … -
Impact of intermittent preventive treatment of malaria in pregnancy with sulfadoxine-pyrimethamine on sexually transmitted and reproductive tract infections: results from a randomised trial in Uganda.
medRxiv : the preprint server for health sciences 2025 Adrama H, Dela Cruz EJ, Ozarslan N, Kakuru A, Odongo B, Gaw SL, Benjamin-Chung J, Kizza J, Aguti M, Ategeka J, Olwoch P, Nakalembe M, Opira B, Clark TD, Kamya MR, Rosenthal PJ, Dorsey G, Roh ME -
Potent Acridone Antimalarial against All Three Life Stages of Plasmodium.
Research square 2025 Kancharla P, Dodean RA, Li Y, Zhang X, Kelly S, Charlton J, Binauhan A, Garcia L, Caridha D, Madejczyk MS, Jin X, Dennis WE, Kudyba K, McEnearney S, Lee PJ, Blount C, DeLuca J, Vuong C, Pannone K, … -
Highly multiplexed molecular inversion probe panel in Plasmodium falciparum targeting common SNPs approximates whole-genome sequencing assessments for selection and relatedness.
Frontiers in genetics 2025 Niaré K, Crudale R, Fola AA, Wernsman Young N, Asua V, Conrad MD, Gashema P, Ghansah A, Hangi S, Ishengoma DS, Mazarati JB, Zeleke AJ, Rosenthal PJ, Djimdé AA, Juliano JJ, Bailey JA -
Performance of molecular inversion probe DR23K and Paragon MAD4HatTeR Amplicon sequencing panels for detection of Plasmodium falciparum mutations associated with antimalarial drug resistance.
Malaria journal 2025 Katairo T, Asua V, Nsengimaana B, Tukwasibwe S, Semakuba FD, Wiringilimaana I, Kagurusi BA, Mwubaha C, Nakasaanya J, Garg S, Kiyaga S, Mbabazi M, Kabbale KD, Ayitewala A, Nsobya SL, Kamya MR, … -
Optimization of Tambjamines Active against Multiple Stages of Malaria Parasites.
Journal of medicinal chemistry 2025 Kumar A, Li Y, Zhang X, Jin X, Dennis WE, Chetree R, Blount C, Caridha D, Madejczyk MS, Lee PJ, Pannone K, DeLuca J, Vuong C, Leed S, Dinh HT, Mdaki K, Mahato R, Sen P, Mondal T, Phukan K, Saha A, … -
Slowing the spread of treatment failure to artemisinin-based combination therapies in Uganda.
medRxiv : the preprint server for health sciences 2025 Nguyen TD, Zupko RJ, Conrad MD, Rukundo GB, Farinha CC, Asua VD, Tran KT, Grace DM, Rosenthal PJ, Agaba BB, Kamya MR, Opigo J, Boni MF -
Development of Next-Generation Antimalarial Acridones with Radical Cure Potential.
Journal of medicinal chemistry 2025 Dodean RA, Li Y, Zhang X, Caridha D, Madejczyk MS, Jin X, Dennis WE, Chetree R, Kudyba K, McEnearney S, Lee PJ, Blount C, DeLuca J, Vuong C, Pannone K, Dinh HT, Mdaki K, Leed S, Martin ML, Pybus BS, … -
Long-term efficacy and safety of sofosbuvir-based direct-acting antiviral regimens in paediatric patients with hepatitis C virus infection: an international registry study.
The Lancet. Child & adolescent health 2025 Gonzalez-Peralta RP, Wen JW, Hardikar W, Karnsakul WW, Whitworth S, Lin CH, Indolfi G, Rosenthal P, Balistreri W, Schwarz KB, Honegger JR, Zhang X, Svarovskaia EC, Suri V, Kersey K, Leung DH -
Selection of Plasmodium falciparum kelch13 mutations in Uganda in comparison with southeast Asia: a modelling study.
The Lancet. Microbe 2025 Meier-Scherling CPG, Watson OJ, Asua V, Ghinai I, Katairo T, Garg S, Conrad MD, Rosenthal PJ, Okell LC, Bailey JA -
Highly multiplex molecular inversion probe panel in Plasmodium falciparum targeting common SNPs approximates whole genome sequencing assessments for selection and relatedness.
medRxiv : the preprint server for health sciences 2025 Niaré K, Crudale R, Fola AA, Wernsman Young N, Asua V, Conrad M, Gashema P, Ghansah A, Hangi S, Ishengoma DS, Mazarati JB, Zeleke AJ, Rosenthal PJ, Djimdé AA, Juliano JJ, Bailey JA -
US Public Health and Biomedical Research Institutions Help Keep the World Safe and Deserve Continued Strong Support.
The American journal of tropical medicine and hygiene 2025 Rosenthal PJ, Hamer DH, Bausch DG, Nishi JB, Fidock DA -
Placental malaria induces a unique methylation profile associated with fetal growth restriction.
Epigenetics 2025 Ozarslan N, Mong C, Ategeka J, Li L, Buarpung S, Robinson JF, Kizza J, Kakuru A, Kamya MR, Dorsey G, Rosenthal PJ, Gaw SL -
Relating household entomological measures to individual malaria risk.
Research square 2025 McClure M, Arinaitwe E, Kamya MR, Rosenthal PJ, Nankabirwa J, Maxwell K, Musiime A, Dorsey G, Greenhouse B, Rodriguez-Barraquer I -
Increased serum GM-CSF at diagnosis of biliary atresia is associated with improved biliary drainage.
Pediatric research 2025 Taylor SA, Harpavat S, Gromer KD, Andreev V, Loomes KM, Bezerra JA, Jarasvaraparn C, Wang K, Horslen S, Rosenthal P, Teckman J, Valentino PL, Ng VL, Karpen SJ, Sokol RJ, Alonso EM, Mack CL, Childhood … -
Performance of Molecular Inversion Probe DR23K and Paragon MAD4HatTeR Amplicon Sequencing Panels for Detection of Plasmodium falciparum Mutations Associated with Antimalarial Drug Resistance.
Research square 2025 Katairo T, Asua V, Nsengimaana B, Tukwasibwe S, Semakuba FD, Wiringilimaana I, Garg S, Kiyaga S, Mbabazi M, Kabbale KD, Ayitewala A, Nsobya SL, Kamya MR, Ssewanyana I, Bailey JA, Aranda-Díaz A, … -
Artemisinin Partial Resistance and the Treatment of Severe Malaria.
JAMA 2025 Rosenthal PJ -
Changes in susceptibility of Plasmodium falciparum to antimalarial drugs in Uganda over time: 2019-2024.
medRxiv : the preprint server for health sciences 2025 Okitwi M, Orena S, Tumwebaze PK, Katairo T, Taremwa Y, Byaruhanga O, Tukwasibwe S, Nsobya SL, Legac J, Cooper RA, Conrad MD, Rosenthal PJ -
Regional action needed to halt antimalarial drug resistance in Africa.
Lancet (London, England) 2024 Martinez-Vega R, Ishengoma DS, Gosling R, Rosenthal PJ, Dondorp A, Barnes KI, Nsanzabana C, Djimde AA, Ochola-Oyier LI, Tibenderana J, Chimumbwa J, Golassa L, Kapologwe NA, Mbacham WF, Kamya MR, … -
Inhibitors of malaria parasite cyclic nucleotide phosphodiesterases block asexual blood-stage development and mosquito transmission.
Science advances 2024 Gomez-Gonzalez PJ, Gupta A, Drought LG, Patel A, Okombo J, van der Watt M, Walker-Gray R, Schindler KA, Burkhard AY, Yeo T, Narwal SK, Bloxham TS, Flueck C, Walker EM, Rey JA, Fairhurst KJ, Reader J, … -
Systematic in vitro evolution in Plasmodium falciparum reveals key determinants of drug resistance.
Science (New York, N.Y.) 2024 Luth MR, Godinez-Macias KP, Chen D, Okombo J, Thathy V, Cheng X, Daggupati S, Davies H, Dhingra SK, Economy JM, Edgar RCS, Gomez-Lorenzo MG, Istvan ES, Jado JC, LaMonte GM, Melillo B, Mok S, Narwal SK… -
The extended recovery ring-stage survival assay is a scalable alternative for artemisinin susceptibility phenotyping of fresh Plasmodium falciparum isolates.
Antimicrobial agents and chemotherapy 2024 Okitwi M, Shoue DA, Checkley LA, Orena S, Ceja FG, Taremwa Y, Tumwebaze PK, Katairo T, Byaruhanga O, Sievert MA, Garg S, Kreutzfeld OK, Legac J, Bailey JA, Nsobya SL, Conrad MD, Rosenthal PJ, Ferdig … -
Remoscope: a label-free imaging cytometer for malaria diagnostics.
medRxiv : the preprint server for health sciences 2024 Lebel PM, Jeyakumar I, Khoo MWL, Charlton C, Saxena A, Jacobsen A, James E, Huynh E, Wu W, Courville G, Fu PC, Raghavan M, Puccinelli R, Peter O, Dorsey G, Rosenthal P, DeRisi J, Gomez-Sjoberg R -
Tambjamines as Fast-Acting Multistage Antimalarials.
ACS infectious diseases 2024 Kumar A, Li Y, Dodean RA, Roth A, Caridha D, Madejczyk MS, Jin X, Dennis WE, Lee PJ, Pybus BS, Martin M, Pannone K, Dinh HT, Blount C, Chetree R, DeLuca J, Evans M, Nadeau R, Vuong C, Leed S, Black C,… -
Refugees.
The American journal of tropical medicine and hygiene 2024 Rosenthal PJ -
Natural killer cell antibody-dependent cellular cytotoxicity to Plasmodium falciparum is impacted by cellular phenotypes, erythrocyte polymorphisms, parasite diversity and intensity of transmission.
Clinical & translational immunology 2024 Tukwasibwe S, Lewis SN, Taremwa Y, van der Ploeg K, Press KD, Ty M, Namirimu Nankya F, Musinguzi K, Nansubuga E, Bach F, Chamai M, Okitwi M, Tumusiime G, Nakimuli A, Colucci F, Kamya MR, Nankabirwa JI… -
The 2024 Public Health Emergency of International Concern: A Global Failure to Control Mpox.
The American journal of tropical medicine and hygiene 2024 Zumla A, Rosenthal PJ, Sam-Agudu NA, Ogoina D, Mbala-Kingebeni P, Ntoumi F, Nakouné E, Njouom R, Ndembi N, Mills EJ, Muyembe-Tamfum JJ, Nachega JB -
Drug-Drug Interaction Between Dihydroartemisinin-Piperaquine and Sulfadoxine-Pyrimethamine During Malaria Chemoprevention in Pregnant Women.
Clinical pharmacology and therapeutics 2024 Mwebaza N, Roh ME, Geng YZ, Opio L, Opira B, Marzan F, Mwima MW, Ssemukuye T, Guo K, Gingrich D, Fotaki N, Kakuru A, Kizza J, Aguti M, Adrama H, Kamya M, Dorsey G, Rosenthal PJ, Aweeka FT, Huang L -
Gestational SARS-CoV-2 Infection in a Ugandan Birth Cohort: High Incidence, Mild Maternal Disease, and Evidence of Association with Transient Infant Stunting.
The American journal of tropical medicine and hygiene 2024 Jacobson KB, Röltgen K, Lam B, Nayebare P, Kakuru A, Kizza J, Aguti M, Nankya F, Briggs J, Takahashi S, Greenhouse B, Rodriguez-Barraquer I, van der Ploeg K, Wohlstadter JN, Sigal GB, Roh ME, … -
Environmental toxicants modulate disease severity in pediatric metabolic dysfunction-associated steatohepatitis.
Journal of pediatric gastroenterology and nutrition 2024 Jain AK, Busgang SA, Gennings C, Yates KP, Schwimmer JB, Rosenthal P, Murray KF, Molleston JP, Scheimann A, Xanthakos SA, Behling CA, Carpenter D, Fishbein M, Neuschwander-Tetri BA, Tonasia J, Vos MB -
Synthesis and In Vivo Profiling of Desymmetrized Antimalarial Trioxolanes with Diverse Carbamate Side Chains.
ACS medicinal chemistry letters 2024 Klope MT, Tapia Cardona JA, Chen J, Gonciarz RL, Cheng K, Jaishankar P, Kim J, Legac J, Rosenthal PJ, Renslo AR -
Dramatic resurgence of malaria after 7 years of intensive vector control interventions in Eastern Uganda.
PLOS global public health 2024 Kamya MR, Nankabirwa JI, Arinaitwe E, Rek J, Zedi M, Maiteki-Sebuguzi C, Opigo J, Staedke SG, Oruni A, Donnelly MJ, Greenhouse B, Briggs J, Krezanoski PJ, Bousema T, Rosenthal PJ, Olwoch P, … -
Varied Prevalence of Antimalarial Drug Resistance Markers in Different Populations of Newly Arrived Refugees in Uganda.
The Journal of infectious diseases 2024 Tukwasibwe S, Garg S, Katairo T, Asua V, Kagurusi BA, Mboowa G, Crudale R, Tumusiime G, Businge J, Alula D, Kasozi J, Wadembere I, Ssewanyana I, Arinaitwe E, Nankabirwa JI, Nsobya SL, Kamya MR, … -
Ex vivo susceptibilities to ganaplacide and diversity in potential resistance mediators in Ugandan Plasmodium falciparum isolates.
Antimicrobial agents and chemotherapy 2024 Kreutzfeld O, Orena S, Okitwi M, Tumwebaze PK, Byaruhanga O, Katairo T, Conrad MD, Legac J, Garg S, Crudale R, Aydemir O, Giesbrecht D, Nsobya SL, Blasco B, Duffey M, Rouillier M, Bailey JA, Cooper RA… -
Artemisinin-resistant malaria in Africa demands urgent action.
Science (New York, N.Y.) 2024 Dhorda M, Kaneko A, Komatsu R, Kc A, Mshamu S, Gesase S, Kapologwe N, Assefa A, Opigo J, Adoke Y, Ebong C, Karema C, Uwimana A, Mangara JN, Amaratunga C, Peto TJ, Tripura R, Callery JJ, Adhikari B, … -
Urgent action is needed to confront artemisinin partial resistance in African malaria parasites.
Nature medicine 2024 Ishengoma DS, Gosling R, Martinez-Vega R, Beshir KB, Bailey JA, Chimumbwa J, Sutherland C, Conrad MD, Tadesse FG, Juliano JJ, Kamya MR, Mbacham WF, Ménard D, Rosenthal PJ, Raman J, Tatarsky A, Tessema… -
Gravidity influences distinct transcriptional profiles of maternal and fetal placental macrophages at term.
Frontiers in immunology 2024 Ozarslan N, Robinson JF, Buarpung S, Kim MY, Ansbro MR, Akram J, Montoya DJ, Kamya MR, Kakuru A, Dorsey G, Rosenthal PJ, Cheng G, Feeney ME, Fisher SJ, Gaw SL -
Author Correction: Emergence, transmission dynamics and mechanisms of artemisinin partial resistance in malaria parasites in Africa.
Nature reviews. Microbiology 2024 Rosenthal PJ, Asua V, Conrad MD -
The surge of mpox in Africa: a call for action.
The Lancet. Global health 2024 Nachega JB, Sam-Agudu NA, Ogoina D, Mbala-Kingebeni P, Ntoumi F, Nakouné E, Njouom R, Lewis RF, Gandhi M, Rosenthal PJ, Rawat A, Wilson LA, Kindrachuk J, Liesenborghs L, Mills EJ, Preiser W, Rimoin AW… -
Efficacy and safety of odevixibat in patients with Alagille syndrome (ASSERT): a phase 3, double-blind, randomised, placebo-controlled trial.
The lancet. Gastroenterology & hepatology 2024 Ovchinsky N, Aumar M, Baker A, Baumann U, Bufler P, Cananzi M, Czubkowski P, Durmaz Ö, Fischer R, Indolfi G, Karnsakul WW, Lacaille F, Lee WS, Maggiore G, Rosenthal P, Ruiz M, Sokal E, Sturm E, van … -
Sofosbuvir-velpatasvir in children 3-17 years old with hepatitis C virus infection.
Journal of pediatric gastroenterology and nutrition 2024 Jonas MM, Romero R, Rosenthal P, Lin CH, Verucchi G, Wen J, Balistreri WF, Whitworth S, Bansal S, Leung DH, Narkewicz MR, Gonzalez-Peralta RP, Mangia A, Karnsakul W, Rao GS, Shao J, de Jong J, Parhy B… -
Development of Novel Peptidyl Nitriles Targeting Rhodesain and Falcipain-2 for the Treatment of Sleeping Sickness and Malaria.
International journal of molecular sciences 2024 Di Chio C, Starvaggi J, Totaro N, Previti S, Natale B, Cosconati S, Bogacz M, Schirmeister T, Legac J, Rosenthal PJ, Zappalà M, Ettari R -
The emergence of artemisinin partial resistance in Africa: how do we respond?
The Lancet. Infectious diseases 2024 Rosenthal PJ, Asua V, Bailey JA, Conrad MD, Ishengoma DS, Kamya MR, Rasmussen C, Tadesse FG, Uwimana A, Fidock DA -
Dramatic resurgence of malaria after 7 years of intensive vector control interventions in Eastern Uganda.
medRxiv : the preprint server for health sciences 2024 Kamya MR, Nankabirwa JI, Arinaitwe E, Rek J, Zedi M, Maiteki-Sebuguzi C, Opigo J, Staedke SG, Oruni A, Donnelly MJ, Greenhouse B, Briggs J, Krezanoski PJ, Bousema T, Rosenthal PJ, Olwoch P, … -
Food insecurity is a risk factor for metabolic dysfunction-associated steatotic liver disease in Latinx children.
Pediatric obesity 2024 Maxwell SL, Price JC, Perito ER, Rosenthal P, Wojcicki JM -
Diagnostic accuracy of serum matrix metalloproteinase-7 as a biomarker of biliary atresia in a large North American cohort.
Hepatology (Baltimore, Md.) 2024 Pandurangi S, Mourya R, Nalluri S, Fei L, Dong S, Harpavat S, Guthery SL, Molleston JP, Rosenthal P, Sokol RJ, Wang KS, Ng V, Alonso EM, Hsu EK, Karpen SJ, Loomes KM, Magee JC, Shneider BL, Horslen SP… -
Ex vivo drug susceptibility and resistance mediating genetic polymorphisms of Plasmodium falciparum in Bobo-Dioulasso, Burkina Faso.
Antimicrobial agents and chemotherapy 2024 Somé AF, Conrad MD, Kabré Z, Fofana A, Yerbanga RS, Bazié T, Neya C, Somé M, Kagambega TJ, Legac J, Garg S, Bailey JA, Ouédraogo J-B, Rosenthal PJ, Cooper RA -
Real-world experience of maralixibat in Alagille syndrome: Novel findings outside of clinical trials.
Journal of pediatric gastroenterology and nutrition 2024 Himes R, Rosenthal P, Dilwali N, Smith K, Venick R, Gonzalez-Peralta RP -
Emergence, transmission dynamics and mechanisms of artemisinin partial resistance in malaria parasites in Africa.
Nature reviews. Microbiology 2024 Rosenthal PJ, Asua V, Conrad MD -
Selection of artemisinin partial resistance Kelch13 mutations in Uganda in 2016-22 was at a rate comparable to that seen previously in South-East Asia.
medRxiv : the preprint server for health sciences 2024 Meier-Scherling CPG, Watson OJ, Asua V, Ghinai I, Katairo T, Garg S, Conrad M, Rosenthal PJ, Okell LC, Bailey JA -
Determination of sulfadoxine and pyrimethamine in microvolume human plasma using ultra high performance liquid chromatography-tandam mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2024 Sok V, Marzan F, Roh M, Guo K, Legac J, Mwebaza N, Dorsey G, Rosenthal PJ, Aweeka FT, Huang L -
Discovery of Potent Antimalarial Type II Kinase Inhibitors with Selectivity over Human Kinases.
Journal of medicinal chemistry 2024 Wang L, Bohmer MJ, Wang J, Nardella F, Calla J, Laureano De Souza M, Schindler KA, Montejo L, Mittal N, Rocamora F, Treat M, Charlton JT, Tumwebaze PK, Rosenthal PJ, Cooper RA, Chakrabarti R, Winzeler… -
Protein biomarkers GDF15 and FGF21 to differentiate mitochondrial hepatopathies from other pediatric liver diseases.
Hepatology communications 2024 Van Hove JLK, Friederich MW, Strode DK, Van Hove RA, Miller KR, Sharma R, Shah H, Estrella J, Gabel L, Horslen S, Kohli R, Lovell MA, Miethke AG, Molleston JP, Romero R, Squires JE, Alonso EM, Guthery… -
Diagnosis and management of Alagille and progressive familial intrahepatic cholestasis.
Hepatology communications 2023 Cheng K, Rosenthal P -
Neonatal cholestasis in children with Alpha-1-AT deficiency is a risk for earlier severe liver disease with male predominance.
Hepatology communications 2023 Teckman J, Rosenthal P, Ignacio RV, Spino C, Bass LM, Horslen S, Wang K, Magee JC, Karpen S, Asai A, Molleston JP, Squires RH, Kamath BM, Guthery SL, Loomes KM, Shneider BL, Sokol RJ, ChiLDReN (… -
Nutrition assessment and MASH severity in children using the Healthy Eating Index.
Hepatology communications 2023 Jain AK, Buchannan P, Yates KP, Belt P, Schwimmer JB, Rosenthal P, Murray KF, Molleston JP, Scheimann A, Xanthakos SA, Behling CA, Hertel P, Nilson J, Neuschwander-Tetri BA, Tonascia J, Vos MB, … -
Naphthyl bearing 1,3,4-thiadiazoleacetamides targeting the parasitic folate pathway as anti-infectious agents: in silico, synthesis, and biological approach.
RSC medicinal chemistry 2023 Pal K, Lala S, Agarwal P, Patel TS, Legac J, Rahman MA, Ahmedi S, Shahid N, Singh S, Kumari K, Madhav H, Sen A, Manzoor N, Dixit BC, Van Zyl R, Rosenthal PJ, Hoda N -
Sarcopenia is associated with osteopenia and impaired quality of life in children with genetic intrahepatic cholestatic liver disease.
Hepatology communications 2023 Boster JM, Goodrich NP, Spino C, Loomes KM, Alonso EM, Kamath BM, Sokol RJ, Karpen S, Miethke A, Shneider BL, Molleston JP, Kohli R, Horslen SP, Rosenthal P, Valentino PL, Teckman JH, Hangartner TN, … -
Seasonal Malaria Chemoprevention Drug Levels and Drug Resistance Markers in Children With or Without Malaria in Burkina Faso: A Case-Control Study.
The Journal of infectious diseases 2023 Roh ME, Zongo I, Haro A, Huang L, Somé AF, Yerbanga RS, Conrad MD, Wallender E, Legac J, Aweeka F, Ouédraogo JB, Rosenthal PJ -
Distinct transcriptional profiles of maternal and fetal placental macrophages at term are associated with gravidity.
bioRxiv : the preprint server for biology 2023 Ozarslan N, Robinson JF, Buarpung S, Kim MY, Ansbro MR, Akram J, Montoya DJ, Kamya MR, Kakuru A, Dorsey G, Rosenthal PJ, Cheng G, Feeney ME, Fisher SJ, Gaw SL -
Change in Health-Related Quality of Life in Youth with Chronic Hepatitis B Living in North America: A 5-Year Cohort Study.
Journal of pediatric gastroenterology and nutrition 2023 Schwarzenberg SJ, King WC, Ling SC, Murray KF, Mogul D, Rosenthal P, Rodriguez-Baez N, Teckman J, Schwarz KB, Hepatitis B Research Network (HBRN) -
Malaria-specific Type 1 regulatory T cells are more abundant in first pregnancies and associated with placental malaria.
EBioMedicine 2023 Kirosingh AS, Delmastro A, Kakuru A, van der Ploeg K, Bhattacharya S, Press KD, Ty M, Parte L, Kizza J, Muhindo M, Devachanne S, Gamain B, Nankya F, Musinguzi K, Rosenthal PJ, Feeney ME, Kamya M, … -
Evolution of Partial Resistance to Artemisinins in Malaria Parasites in Uganda.
The New England journal of medicine 2023 Conrad MD, Asua V, Garg S, Giesbrecht D, Niaré K, Smith S, Namuganga JF, Katairo T, Legac J, Crudale RM, Tumwebaze PK, Nsobya SL, Cooper RA, Kamya MR, Dorsey G, Bailey JA, Rosenthal PJ -
The Human Mpox Global Outbreak: Available Control Tools and the Opportunity to Break a Cycle of Neglect in Endemic Countries.
The American journal of tropical medicine and hygiene 2023 Nachega JB, Mbala-Kingebeni P, Rosenthal PJ, Rimoin AW, Hoff NA, Liesenborghs L, Vanlerberghe V, Andrei G, Rawat A, Wilson LA, Forrest J, Mills EJ, Hermans MP, Mulangu S, Ntoumi F, Zumla A, Muyembe-… -
Proteasome inhibitors: The next generation of antimalarial drugs?
Cell chemical biology 2023 Rosenthal PJ -
Clinical spectrum and genetic causes of mitochondrial hepatopathy phenotype in children.
Hepatology communications 2023 Squires JE, Miethke AG, Valencia CA, Hawthorne K, Henn L, Van Hove JLK, Squires RH, Bove K, Horslen S, Kohli R, Molleston JP, Romero R, Alonso EM, Bezerra JA, Guthery SL, Hsu E, Karpen SJ, Loomes KM, … -
Safety and yield of percutaneous liver biopsy in adults and children with chronic hepatitis B: Results from a prospective, multicenter study.
Hepatology communications 2023 Ghany MG, Belle SH, Kleiner DE, Smith C, Kelley SS, Rosenthal P, Fontana RJ, Hepatitis B Research Network -
Susceptibility of Ugandan Plasmodium falciparum Isolates to the Antimalarial Drug Pipeline.
Microbiology spectrum 2023 Kreutzfeld O, Tumwebaze PK, Okitwi M, Orena S, Byaruhanga O, Katairo T, Conrad MD, Rasmussen SA, Legac J, Aydemir O, Giesbrecht D, Forte B, Campbell P, Smith A, Kano H, Nsobya SL, Blasco B, Duffey M, … -
Influence of amino acid size at the P3 position of N-Cbz-tripeptide Michael acceptors targeting falcipain-2 and rhodesain for the treatment of malaria and human african trypanosomiasis.
Bioorganic chemistry 2023 Previti S, Ettari R, Di Chio C, Legac J, Bogacz M, Zimmer C, Schirmeister T, Rosenthal PJ, Zappalà M -
Artefenomel Regioisomer RLA-3107 Is a Promising Lead for the Discovery of Next-Generation Endoperoxide Antimalarials.
ACS medicinal chemistry letters 2023 Blank BR, Gut J, Rosenthal PJ, Renslo AR -
Shorter leukocyte telomere length protects against NAFLD progression in children.
Scientific reports 2023 Wojcicki JM, Gill RM, Wilson L, Lin J, Rosenthal P -
Efavirenz-Based Antiretroviral Therapy but Not Pregnancy Increased Unbound Piperaquine Exposure in Women during Malaria Chemoprevention.
Antimicrobial agents and chemotherapy 2023 Hong H, Aslam-Mir U, Kajubi R, Wallender E, Mwebaza N, Dorsey G, Rosenthal PJ, Aweeka FT, Huang L -
Serum bile acids as a prognostic biomarker in biliary atresia following Kasai portoenterostomy.
Hepatology (Baltimore, Md.) 2023 Harpavat S, Hawthorne K, Setchell KDR, Rivas MN, Henn L, Beil CA, Karpen SJ, Ng VL, Alonso EM, Bezerra JA, Guthery SL, Horslen S, Loomes KM, McKiernan P, Magee JC, Merion RM, Molleston JP, Rosenthal P… -
Elbasvir/grazoprevir in children aged 3-18 years with chronic HCV genotype 1 or 4 infection: a pharmacokinetic modeling study.
Hepatology communications 2023 Gonzalez-Peralta RP, Wirth S, Squires RH, Mutschler F, Lang T, Pawlowska M, Sluzewski W, Majda-Stanislawska E, Fischler B, Balistreri WF, Jonas MM, Blondet N, Rosenthal P, Alkhouri N, Romero R, … -
Costs of pediatric liver transplantation among commercially insured and Medicaid-insured patients with cholestasis in the US.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2023 Miloh T, Goldstein A, Howard R, Mogul DB, Marden JR, Anderson A, Gaburo K, Kirson N, Rosenthal P -
Seroprevalence of Antibodies to SARS-CoV-2 in Rural Households in Eastern Uganda, 2020-2022.
JAMA network open 2023 Briggs J, Takahashi S, Nayebare P, Cuu G, Rek J, Zedi M, Kizza T, Arinaitwe E, Nankabirwa JI, Kamya M, Jagannathan P, Jacobson K, Rosenthal PJ, Dorsey G, Greenhouse B, Ssewanyana I, Rodríguez-… -
Structure-Activity Relationship Studies of Antimalarial Plasmodium Proteasome Inhibitors─Part II.
Journal of medicinal chemistry 2023 Zhang H, Ginn J, Zhan W, Leung A, Liu YJ, Toita A, Okamoto R, Wong TT, Imaeda T, Hara R, Michino M, Yukawa T, Chelebieva S, Tumwebaze PK, Vendome J, Beuming T, Sato K, Aso K, Rosenthal PJ, Cooper RA, … -
Measures of malaria transmission, infection, and disease in an area bordering two districts with and without sustained indoor residual spraying of insecticide in Uganda.
PloS one 2022 Nankabirwa JI, Bousema T, Blanken SL, Rek J, Arinaitwe E, Greenhouse B, Rosenthal PJ, Kamya MR, Staedke SG, Dorsey G -
Identification, in-vitro anti-plasmodial assessment and docking studies of series of tetrahydrobenzothieno[2,3-d]pyrimidine-acetamide molecular hybrids as potential antimalarial agents.
European journal of medicinal chemistry 2022 Pal K, Raza MK, Legac J, Rahman A, Manzoor S, Bhattacharjee S, Rosenthal PJ, Hoda N -
Advancing detection and response capacities for emerging and re-emerging pathogens in Africa.
The Lancet. Infectious diseases 2022 Nachega JB, Nsanzimana S, Rawat A, Wilson LA, Rosenthal PJ, Siedner MJ, Varma JK, Kilmarx PH, Mutesa L, Tanner M, Binagwaho A, Forrest J, Mbala-Kingebeni P, Muyembe-Tamfum JJ, Ntoumi F, Zumla A, de … -
Impact of different mosquito collection methods on indicators of Anopheles malaria vectors in Uganda.
Malaria journal 2022 Mawejje HD, Asiimwe JR, Kyagamba P, Kamya MR, Rosenthal PJ, Lines J, Dorsey G, Staedke SG -
Characterizing pyrethroid resistance and mechanisms in Anopheles gambiae (s.s.) and Anopheles arabiensis from 11 districts in Uganda.
Current research in parasitology & vector-borne diseases 2022 Mawejje HD, Weetman D, Epstein A, Lynd A, Opigo J, Maiteki-Sebuguzi C, Lines J, Kamya MR, Rosenthal PJ, Donnelly MJ, Dorsey G, Staedke SG -
Quinoline-based heterocyclic hydrazones: Design, synthesis, anti-plasmodial assessment, and mechanistic insights.
Chemical biology & drug design 2022 Sharma B, Chowdhary S, Legac J, Rosenthal PJ, Kumar V -
Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Pregnancy in Sub-Saharan Africa: A 6-Country Retrospective Cohort Analysis.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2022 Nachega JB, Sam-Agudu NA, Machekano RN, Rosenthal PJ, Schell S, de Waard L, Bekker A, Gachuno OW, Kinuthia J, Mwongeli N, Budhram S, Vannevel V, Somapillay P, Prozesky HW, Taljaard J, Parker A, Agyare… -
Response to "The Importance of Exercising Caution When Comparing Results from Malaria Vaccines Administered on the EPI Schedule and on a Seasonal Schedule".
The American journal of tropical medicine and hygiene 2022 Rosenthal PJ -
Genotype-phenotype relationships of truncating mutations, p.E297G and p.D482G in bile salt export pump deficiency.
JHEP reports : innovation in hepatology 2022 Felzen A, van Wessel DBE, Gonzales E, Thompson RJ, Jankowska I, Shneider BL, Sokal E, Grammatikopoulos T, Kadaristiana A, Jacquemin E, Spraul A, Lipinski P, Czubkowski P, Rock N, Shagrani M, Broering … -
Serum biomarkers correlated with liver stiffness assessed in a multicenter study of pediatric cholestatic liver disease.
Hepatology (Baltimore, Md.) 2022 Leung DH, Devaraj S, Goodrich NP, Chen X, Rajapakshe D, Ye W, Andreev V, Minard CG, Guffey D, Molleston JP, Bass LM, Karpen SJ, Kamath BM, Wang KS, Sundaram SS, Rosenthal P, McKiernan P, Loomes KM, … -
Decreased susceptibility of Plasmodium falciparum to both dihydroartemisinin and lumefantrine in northern Uganda.
Nature communications 2022 Tumwebaze PK, Conrad MD, Okitwi M, Orena S, Byaruhanga O, Katairo T, Legac J, Garg S, Giesbrecht D, Smith SR, Ceja FG, Nsobya SL, Bailey JA, Cooper RA, Rosenthal PJ -
Prioritizing Pregnant Women for Coronavirus Disease 2019 Vaccination in African Countries.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2022 Nachega JB, Sam-Agudu NA, Siedner MJ, Rosenthal PJ, Mellors JW, Zumla A, Hermans MP, Ntakwinja MB, Mukwege DM, Langenegger E, Mofenson LM, African Forum for Research and Education in Health (… -
East Africa International Center of Excellence for Malaria Research: Impact on Malaria Policy in Uganda.
The American journal of tropical medicine and hygiene 2022 Namuganga JF, Nankabirwa JI, Maiteki-Ssebuguzi C, Gonahasa S, Opigo J, Staedke SG, Rutazaana D, Ebong C, Dorsey G, Tomko SS, Kizza T, Mawejje HD, Arinaitwe E, Rosenthal PJ, Kamya MR -
East Africa International Center of Excellence for Malaria Research: Summary of Key Research Findings.
The American journal of tropical medicine and hygiene 2022 Nankabirwa JI, Rek J, Arinaitwe E, Namuganga JF, Nsobya SL, Asua V, Mawejje HD, Epstein A, Greenhouse B, Rodriguez-Barraquer I, Briggs J, Krezanoski PJ, Rosenthal PJ, Conrad M, Smith D, Staedke SG, … -
Simulating the Impacts of Augmenting Intensive Vector Control with Mass Drug Administration or Test-and-Treat Strategies on the Malaria Infectious Reservoir.
The American journal of tropical medicine and hygiene 2022 Nankabirwa JI, Arinaitwe E, Briggs J, Rek J, Rosenthal PJ, Kamya MR, Olwoch P, Smith DL, Rodriguez-Barraquer I, Dorsey G, Greenhouse B -
Health Care Resource Utilization by Patients with Alagille Syndrome.
The Journal of pediatrics 2022 Ebel NH, Goldstein A, Howard R, Mogul DB, Marden JR, Anderson A, Gaburo K, Kirson N, Rosenthal P -
Reconstructing the SARS-CoV-2 epidemic in eastern Uganda through longitudinal serosurveillance in a malaria cohort.
medRxiv : the preprint server for health sciences 2022 Briggs J, Takahashi S, Nayebare P, Cuu G, Rek J, Zedi M, Kizza T, Arinaitwe E, Nankabirwa JI, Kamya M, Jagannathan P, Jacobson K, Rosenthal PJ, Dorsey G, Greenhouse B, Ssewanyana I, Rodríguez-… -
Susceptibilities of Ugandan Plasmodium falciparum Isolates to Proteasome Inhibitors.
Antimicrobial agents and chemotherapy 2022 Garg S, Kreutzfeld O, Chelebieva S, Tumwebaze PK, Byaruhanga O, Okitwi M, Orena S, Katairo T, Nsobya SL, Conrad MD, Aydemir O, Legac J, Gould AE, Bayles BR, Bailey JA, Duffey M, Lin G, Kirkman LA, … -
Piperaquine-Induced QTc Prolongation Decreases With Repeated Monthly Dihydroartemisinin-Piperaquine Dosing in Pregnant Ugandan Women.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2022 Hughes E, Wallender E, Kajubi R, Jagannathan P, Ochieng T, Kakuru A, Kamya MR, Clark TD, Rosenthal PJ, Dorsey G, Aweeka F, Savic RM -
The Multistage Antimalarial Compound Calxinin Perturbates P. falciparum Ca2+ Homeostasis by Targeting a Unique Ion Channel.
Pharmaceutics 2022 Gupta Y, Sharma N, Singh S, Romero JG, Rajendran V, Mogire RM, Kashif M, Beach J, Jeske W, Ogutu BR, Kanzok SM, Akala HM, Legac J, Rosenthal PJ, Rademacher DJ, Durvasula R, Singh AP, Rathi B, Kempaiah… -
Advances in Pediatric Liver Diseases.
Clinics in liver disease 2022 Rosenthal P -
STARTER Checklist for Antimalarial Therapeutic Efficacy Reporting.
The American journal of tropical medicine and hygiene 2022 Plucinski M, Ashley EA, Bassat Q, Venkatesan M, Rosenthal PJ, Halsey ES -
STARTER checklist for antimalarial therapeutic efficacy reporting.
Malaria journal 2022 Plucinski MM, Ashley EA, Bassat Q, Venkatesan M, Rosenthal PJ, Halsey ES -
Impact of long-term administration of maralixibat on children with cholestasis secondary to Alagille syndrome.
Hepatology communications 2022 Shneider BL, Spino CA, Kamath BM, Magee JC, Ignacio RV, Huang S, Horslen SP, Molleston JP, Miethke AG, Kohli R, Leung DH, Jensen MK, Loomes KM, Karpen SJ, Mack C, Rosenthal P, Squires RH, Baker A, … -
Use of funded multicenter prospective longitudinal databases to inform clinical trials in rare diseases-Examination of cholestatic liver disease in Alagille syndrome.
Hepatology communications 2022 Shneider BL, Kamath BM, Magee JC, Goodrich NP, Loomes KM, Ye W, Spino C, Alonso EM, Molleston JP, Bezerra JA, Wang KS, Karpen SJ, Horslen SP, Guthery SL, Rosenthal P, Squires RH, Sokol RJ, Childhood … -
Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183.
Nature communications 2022 de Vries LE, Jansen PAM, Barcelo C, Munro J, Verhoef JMJ, Pasaje CFA, Rubiano K, Striepen J, Abla N, Berning L, Bolscher JM, Demarta-Gatsi C, Henderson RWM, Huijs T, Koolen KMJ, Tumwebaze PK, Yeo T, … -
Risk of variceal hemorrhage and pretransplant mortality in children with biliary atresia.
Hepatology (Baltimore, Md.) 2022 Bass LM, Ye W, Hawthorne K, Leung DH, Murray KF, Molleston JP, Romero R, Karpen S, Rosenthal P, Loomes KM, Wang KS, Squires RH, Miethke A, Ng VL, Horslen S, Kyle Jensen M, Sokol RJ, Magee JC, Shneider… -
Cooperation in Countering Artemisinin Resistance in Africa: Learning from COVID-19.
The American journal of tropical medicine and hygiene 2022 Rosenthal PJ, Björkman A, Dhorda M, Djimde A, Dondorp AM, Gaye O, Guerin PJ, Juma E, Kwiatkowski DP, Merson L, Ntoumi F, Price RN, Raman J, Roos DS, Ter Kuile F, Tinto H, Tomko SS, White NJ, Barnes KI -
Field evaluation of the diagnostic performance of EasyScan GO: a digital malaria microscopy device based on machine-learning.
Malaria journal 2022 Das D, Vongpromek R, Assawariyathipat T, Srinamon K, Kennon K, Stepniewska K, Ghose A, Sayeed AA, Faiz MA, Netto RLA, Siqueira A, Yerbanga SR, Ouédraogo JB, Callery JJ, Peto TJ, Tripura R, Koukouikila… -
Malaria in 2022: Challenges and Progress.
The American journal of tropical medicine and hygiene 2022 Rosenthal PJ -
Reply to Li, Henry, and Nguyen.
The American journal of gastroenterology 2022 Khalili M, Kleiner DE, King WC, Sterling RK, Ghany MG, Chung RT, Bhan AK, Rosenthal P, Lisker-Melman M, Ramachandran R, Lok AS -
Discovery of spirooxadiazoline oxindoles with dual-stage antimalarial activity.
European journal of medicinal chemistry 2022 Lopes EA, Mestre R, Fontinha D, Legac J, Pei JV, Sanches-Vaz M, Mori M, Lehane AM, Rosenthal PJ, Prudêncio M, Santos MMM -
Changes in serum hepatitis B surface and e antigen, interferon-inducible protein 10, and aminotransferase levels during combination therapy of immune-tolerant chronic hepatitis B.
Hepatology (Baltimore, Md.) 2022 Perrillo R, Lin HS, Schwarz KB, Rosenthal P, Lisker-Melman M, Chung RT, Prokunina-Olsson L, Cloherty G, Feld J, Hepatitis B Research Network (HBRN) -
Determination of unbound piperaquine in human plasma by ultra-high performance liquid chromatography tandem mass spectrometry.
Journal of chromatography open 2022 Huang L, Sok V, Aslam-Mir U, Marzan F, Whalen M, Rosenthal PJ, Aweeka F -
Impact of Short-Term Storage on Ex Vivo Antimalarial Susceptibilities of Fresh Ugandan Plasmodium falciparum Isolates.
Antimicrobial agents and chemotherapy 2022 Okitwi M, Orena S, Thomas K, Tumwebaze PK, Byaruhanga O, Nsobya SL, Conrad MD, Bayles BR, Rosenthal PJ, Cooper RA -
Identification, Characterization, and Synthesis of Natural Parasitic Cysteine Protease Inhibitors: Pentacitidins Are More Potent Falcitidin Analogues.
ACS chemical biology 2022 Brinkmann S, Semmler S, Kersten C, Patras MA, Kurz M, Fuchs N, Hammerschmidt SJ, Legac J, Hammann PE, Vilcinskas A, Rosenthal PJ, Schirmeister T, Bauer A, Schäberle TF -
Assessment of Clinical Outcomes Among Children and Adolescents Hospitalized With COVID-19 in 6 Sub-Saharan African Countries.
JAMA pediatrics 2022 Nachega JB, Sam-Agudu NA, Machekano RN, Rabie H, van der Zalm MM, Redfern A, Dramowski A, O'Connell N, Pipo MT, Tshilanda MB, Byamungu LN, Masekela R, Jeena PM, Pillay A, Gachuno OW, Kinuthia J, … -
Discovery and Preclinical Pharmacology of INE963, a Potent and Fast-Acting Blood-Stage Antimalarial with a High Barrier to Resistance and Potential for Single-Dose Cures in Uncomplicated Malaria.
Journal of medicinal chemistry 2022 Taft BR, Yokokawa F, Kirrane T, Mata AC, Huang R, Blaquiere N, Waldron G, Zou B, Simon O, Vankadara S, Chan WL, Ding M, Sim S, Straimer J, Guiguemde A, Lakshminarayana SB, Jain JP, Bodenreider C, … -
Decreased Susceptibility to Dihydrofolate Reductase Inhibitors Associated With Genetic Polymorphisms in Ugandan Plasmodium falciparum Isolates.
The Journal of infectious diseases 2022 Kreutzfeld O, Tumwebaze PK, Byaruhanga O, Katairo T, Okitwi M, Orena S, Rasmussen SA, Legac J, Conrad MD, Nsobya SL, Aydemir O, Bailey JA, Duffey M, Cooper RA, Rosenthal PJ -
The Inflammatory Cytokine Profile Associated With Liver Damage Is Broader and Stronger in Patients With Chronic Hepatitis B Compared to Patients With Acute Hepatitis B.
The Journal of infectious diseases 2022 Johnson Valiente A, Liem KS, Schwarz KB, Rosenthal P, Murray KF, Mogul D, Teckman J, Rodriguez-Baez N, Schwarzenberg SJ, Feld JJ, Wong DK, Lewis-Ximenez LL, Lauer G, Hansen BE, Ling SC, Janssen HLA, … -
Incidence and prediction of HBsAg seroclearance in a prospective multi-ethnic HBeAg-negative chronic hepatitis B cohort.
Hepatology (Baltimore, Md.) 2022 Terrault NA, Wahed AS, Feld JJ, Cooper SL, Ghany MG, Lisker-Melman M, Perrillo R, Sterling RK, Khalili M, Chung RT, Rosenthal P, Fontana RJ, Sarowar A, Lau DTY, Wang J, Lok AS, Janssen HLA -
Lessons Learned From Children Enrolled Into the Hepatitis B Virus Research Network Multi-Center Prospective Study.
Journal of pediatric gastroenterology and nutrition 2022 Schwarzenberg SJ, Ling SC, Rosenthal P, Murray KF, Teckman J, Mogul D, Rodriguez-Baez N, Schwarz K -
Neurodevelopmental Outcomes in Children With Inherited Liver Disease and Native Liver.
Journal of pediatric gastroenterology and nutrition 2022 Leung DH, Sorensen LG, Ye W, Hawthorne K, Ng VL, Loomes KM, Fredericks EM, Alonso EM, Heubi JE, Horslen SP, Karpen SJ, Molleston JP, Rosenthal P, Sokol RJ, Squires RH, Wang KS, Kamath BM, Magee JC, … -
Organ-Specific Comorbidities Are Associated With Distinct Complications After Liver Transplantation for Biliary Atresia.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2021 Taylor SA, Venkat V, Arnon R, Gopalareddy VV, Rosenthal P, Anderson SG, Anand R, Daniel JF, Society of Pediatric Liver Transplantation -
Artemisinin resistance in Africa: How urgent is the threat?
Med (New York, N.Y.) 2021 Fidock DA, Rosenthal PJ -
Identifying an optimal dihydroartemisinin-piperaquine dosing regimen for malaria prevention in young Ugandan children.
Nature communications 2021 Wallender E, Ali AM, Hughes E, Kakuru A, Jagannathan P, Muhindo MK, Opira B, Whalen M, Huang L, Duvalsaint M, Legac J, Kamya MR, Dorsey G, Aweeka F, Rosenthal PJ, Savic RM -
Comparative Analysis of Plasmodium falciparum Genotyping via SNP Detection, Microsatellite Profiling, and Whole-Genome Sequencing.
Antimicrobial agents and chemotherapy 2021 Kanai M, Yeo T, Asua V, Rosenthal PJ, Fidock DA, Mok S -
Presentation and Outcomes of Infants With Idiopathic Cholestasis: A Multicenter Prospective Study.
Journal of pediatric gastroenterology and nutrition 2021 Hertel PM, Hawthorne K, Kim S, Finegold MJ, Shneider BL, Squires JE, Gupta NA, Bull LN, Murray KF, Kerkar N, Ng VL, Molleston JP, Bezerra JA, Loomes KM, Taylor SA, Schwarz KB, Turmelle YP, Rosenthal P… -
Are Artemisinin-Based Combination Therapies For Malaria Beginning To Fail in Africa?
The American journal of tropical medicine and hygiene 2021 Rosenthal PJ -
Liver transplant in children and adults with cystic fibrosis: Impact of growth failure and nutritional status.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2021 Cheng K, Rosenthal P, Roberts JP, Perito ER -
Associations between Varied Susceptibilities to PfATP4 Inhibitors and Genotypes in Ugandan Plasmodium falciparum Isolates.
Antimicrobial agents and chemotherapy 2021 Kreutzfeld O, Rasmussen SA, Ramanathan AA, Tumwebaze PK, Byaruhanga O, Katairo T, Asua V, Okitwi M, Orena S, Legac J, Conrad MD, Nsobya SL, Aydemir O, Bailey J, Duffey M, Bayles BR, Vaidya AB, Cooper … -
Hepatic Steatosis and Steatohepatitis in a Large North American Cohort of Adults With Chronic Hepatitis B.
The American journal of gastroenterology 2021 Khalili M, Kleiner DE, King WC, Sterling RK, Ghany MG, Chung RT, Bhan AK, Rosenthal P, Lisker-Melman M, Ramachandran R, Lok AS, ; and the Hepatitis B Research Network (HBRN) -
The antimalarial MMV688533 provides potential for single-dose cures with a high barrier to Plasmodium falciparum parasite resistance.
Science translational medicine 2021 Murithi JM, Pascal C, Bath J, Boulenc X, Gnädig NF, Pasaje CFA, Rubiano K, Yeo T, Mok S, Klieber S, Desert P, Jiménez-Díaz MB, Marfurt J, Rouillier M, Cherkaoui-Rbati MH, Gobeau N, Wittlin S, Uhlemann… -
Plasmodium falciparum K13 mutations in Africa and Asia impact artemisinin resistance and parasite fitness.
eLife 2021 Stokes BH, Dhingra SK, Rubiano K, Mok S, Straimer J, Gnädig NF, Deni I, Schindler KA, Bath JR, Ward KE, Striepen J, Yeo T, Ross LS, Legrand E, Ariey F, Cunningham CH, Souleymane IM, Gansané A, … -
Impact of Genotype, Serum Bile Acids, and Surgical Biliary Diversion on Native Liver Survival in FIC1 Deficiency.
Hepatology (Baltimore, Md.) 2021 van Wessel DBE, Thompson RJ, Gonzales E, Jankowska I, Shneider BL, Sokal E, Grammatikopoulos T, Kadaristiana A, Jacquemin E, Spraul A, Lipinski P, Czubkowski P, Rock N, Shagrani M, Broering D, Algoufi… -
Balanced impacts of fitness and drug pressure on the evolution of PfMDR1 polymorphisms in Plasmodium falciparum.
Malaria journal 2021 Duvalsaint M, Conrad MD, Tukwasibwe S, Tumwebaze PK, Legac J, Cooper RA, Rosenthal PJ -
Challenges and opportunities for use of long-lasting insecticidal nets to prevent malaria during overnight travel in Uganda: a qualitative study.
Malaria journal 2021 Ekusai-Sebatta D, Arinaitwe E, Mpimbaza A, Nankabirwa JI, Drakeley C, Rosenthal PJ, Staedke SG, Muyinda H -
Drug susceptibility of Plasmodium falciparum in eastern Uganda: a longitudinal phenotypic and genotypic study.
The Lancet. Microbe 2021 Tumwebaze PK, Katairo T, Okitwi M, Byaruhanga O, Orena S, Asua V, Duvalsaint M, Legac J, Chelebieva S, Ceja FG, Rasmussen SA, Conrad MD, Nsobya SL, Aydemir O, Bailey JA, Bayles BR, Rosenthal PJ, … -
Sources of persistent malaria transmission in a setting with effective malaria control in eastern Uganda: a longitudinal, observational cohort study.
The Lancet. Infectious diseases 2021 Andolina C, Rek JC, Briggs J, Okoth J, Musiime A, Ramjith J, Teyssier N, Conrad M, Nankabirwa JI, Lanke K, Rodriguez-Barraquer I, Meerstein-Kessel L, Arinaitwe E, Olwoch P, Rosenthal PJ, Kamya MR, … -
Chronic Hepatitis Is Common and Often Untreated Among Children with Hepatitis B Infection in the United States and Canada.
The Journal of pediatrics 2021 Ling SC, Lin HS, Murray KF, Rosenthal P, Mogul D, Rodriguez-Baez N, Schwarzenberg SJ, Teckman J, Schwarz KB, Hepatitis B Research Network (HBRN) -
Design, synthesis, crystal structure and anti-plasmodial evaluation of tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine derivatives.
RSC medicinal chemistry 2021 Pal K, Raza MK, Legac J, Ataur Rahman M, Manzoor S, Rosenthal PJ, Hoda N -
Non-operative management of biliary complications after Liver Transplantation in pediatric patients: A 30-year experience.
Pediatric transplantation 2021 Lee AY, Lehrman ED, Perito ER, Kerlan RK, Kohi MP, Kolli KP, Taylor AG, Ostroff JW, Kang SM, Roberts JP, Rhee S, Rosenthal P, Fidelman N -
Use of a Comprehensive 66-Gene Cholestasis Sequencing Panel in 2171 Cholestatic Infants, Children, and Young Adults.
Journal of pediatric gastroenterology and nutrition 2021 Karpen SJ, Kamath BM, Alexander JJ, Ichetovkin I, Rosenthal P, Sokol RJ, Dunn S, Thompson RJ, Heubi JE -
Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series.
Journal of medicinal chemistry 2021 Palmer MJ, Deng X, Watts S, Krilov G, Gerasyuto A, Kokkonda S, El Mazouni F, White J, White KL, Striepen J, Bath J, Schindler KA, Yeo T, Shackleford DM, Mok S, Deni I, Lawong A, Huang A, Chen G, Wang … -
A trio of quinoline-isoniazid-phthalimide with promising antiplasmodial potential: Synthesis, in-vitro evaluation and heme-polymerization inhibition studies.
Bioorganic & medicinal chemistry 2021 Rani A, Sharma A, Legac J, Rosenthal PJ, Singh P, Kumar V -
Has artemisinin resistance emerged in Africa?
The Lancet. Infectious diseases 2021 Rosenthal PJ -
Changing Prevalence of Potential Mediators of Aminoquinoline, Antifolate, and Artemisinin Resistance Across Uganda.
The Journal of infectious diseases 2021 Asua V, Conrad MD, Aydemir O, Duvalsaint M, Legac J, Duarte E, Tumwebaze P, Chin DM, Cooper RA, Yeka A, Kamya MR, Dorsey G, Nsobya SL, Bailey J, Rosenthal PJ -
Life Expectancy after Liver Transplantation for Non-Cirrhotic Hepatocellular Carcinoma.
Progress in transplantation (Aliso Viejo, Calif.) 2021 Shavelle RM, Kwak JH, Saur R, Brooks JC, Rosenthal P -
Development of a Highly Selective Plasmodium falciparum Proteasome Inhibitor with Anti-malaria Activity in Humanized Mice.
Angewandte Chemie (International ed. in English) 2021 Zhan W, Zhang H, Ginn J, Leung A, Liu YJ, Michino M, Toita A, Okamoto R, Wong TT, Imaeda T, Hara R, Yukawa T, Chelebieva S, Tumwebaze PK, Lafuente-Monasterio MJ, Martinez-Martinez MS, Vendome J, … -
Diversity of KIR genes and their HLA-C ligands in Ugandan populations with historically varied malaria transmission intensity.
Malaria journal 2021 Tukwasibwe S, Traherne JA, Chazara O, Jayaraman J, Trowsdale J, Moffett A, Jiang W, Nankabirwa JI, Rek J, Arinaitwe E, Nsobya SL, Atuheirwe M, Frank M, Godwin A, Jagannathan P, Cose S, Kamya MR, … -
Within-household clustering of genetically related Plasmodium falciparum infections in a moderate transmission area of Uganda.
Malaria journal 2021 Briggs J, Kuchta A, Murphy M, Tessema S, Arinaitwe E, Rek J, Chen A, Nankabirwa JI, Drakeley C, Smith D, Bousema T, Kamya M, Rodriguez-Barraquer I, Staedke S, Dorsey G, Rosenthal PJ, Greenhouse B -
Impact of a Rapid Decline in Malaria Transmission on Antimalarial IgG Subclasses and Avidity.
Frontiers in immunology 2021 Ssewanyana I, Rek J, Rodriguez I, Wu L, Arinaitwe E, Nankabirwa JI, Beeson JG, Mayanja-Kizza H, Rosenthal PJ, Dorsey G, Kamya MR, Drakeley C, Greenhouse B, Tetteh KKA -
Prevalence of Malaria Parasite Infections among U.S.-Bound Congolese Refugees with and without Splenomegaly.
The American journal of tropical medicine and hygiene 2021 Mwesigwa M, Webster JL, Nsobya SL, Rowan A, Basnet MS, Phares CR, Weinberg M, Klosovsky A, Naoum M, Rosenthal PJ, Stauffer WM -
Deletions of pfhrp2 and pfhrp3 genes were uncommon in rapid diagnostic test-negative Plasmodium falciparum isolates from Uganda.
Malaria journal 2021 Nsobya SL, Walakira A, Namirembe E, Kiggundu M, Nankabirwa JI, Ruhamyankaka E, Arinaitwe E, Conrad MD, Kamya MR, Dorsey G, Rosenthal PJ -
Year 100 of the American Journal of Tropical Medicine and Hygiene: A Remarkable Year.
The American journal of tropical medicine and hygiene 2021 Rosenthal PJ -
Non-adherence to long-lasting insecticide treated bednet use following successful malaria control in Tororo, Uganda.
PloS one 2020 Rek J, Musiime A, Zedi M, Otto G, Kyagamba P, Asiimwe Rwatooro J, Arinaitwe E, Nankabirwa J, Staedke SG, Drakeley C, Rosenthal PJ, Kamya M, Dorsey G, Krezanoski PJ -
Alanine Aminotransferase and Gamma-Glutamyl Transpeptidase Predict Histologic Improvement in Pediatric Nonalcoholic Steatohepatitis.
Hepatology (Baltimore, Md.) 2020 Newton KP, Lavine JE, Wilson L, Behling C, Vos MB, Molleston JP, Rosenthal P, Miloh T, Fishbein MH, Jain AK, Murray KF, Schwimmer JB, Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN) -
Associations between Malaria-Preventive Regimens and Plasmodium falciparum Drug Resistance-Mediating Polymorphisms in Ugandan Pregnant Women.
Antimicrobial agents and chemotherapy 2020 Nayebare P, Asua V, Conrad MD, Kajubi R, Kakuru A, Nankabirwa JI, Muhanguzi D, Dorsey G, Kamya MR, Nsobya S, Rosenthal PJ -
Piperaquine Exposure Is Altered by Pregnancy, HIV, and Nutritional Status in Ugandan Women.
Antimicrobial agents and chemotherapy 2020 Hughes E, Imperial M, Wallender E, Kajubi R, Huang L, Jagannathan P, Zhang N, Kakuru A, Natureeba P, Mwima MW, Muhindo M, Mwebaza N, Clark TD, Opira B, Nakalembe M, Havlir D, Kamya M, Rosenthal PJ, … -
Association between recent overnight travel and use of long-lasting insecticidal nets in rural Uganda: a prospective cohort study in Tororo.
Malaria journal 2020 Arinaitwe E, Nankabirwa JI, Krezanoski P, Rek J, Kamya V, Epstein A, Rosenthal PJ, Drakeley C, Kamya MR, Dorsey G, Staedke SG -
Resistance to Some But Not Other Dimeric Lindenane Sesquiterpenoid Esters Is Mediated by Mutations in a Plasmodium falciparum Esterase.
ACS infectious diseases 2020 Butler JH, Baptista RP, Valenciano AL, Zhou B, Kissinger JC, Tumwebaze PK, Rosenthal PJ, Cooper RA, Yue JM, Cassera MB -
Modeling Outcomes in Children With Biliary Atresia With Native Liver After 2 Years of Age.
Hepatology communications 2020 Venkat V, Ng VL, Magee JC, Ye W, Hawthorne K, Harpavat S, Molleston JP, Murray KF, Wang KS, Soufi N, Bass LM, Alonso EM, Bezerra JA, Jensen MK, Kamath BM, Loomes KM, Mack CL, Rosenthal P, Shneider BL,… -
Malaria Diagnosed in an Urban Setting Strongly Associated with Recent Overnight Travel: A Case-Control Study from Kampala, Uganda.
The American journal of tropical medicine and hygiene 2020 Arinaitwe E, Mpimbaza A, Nankabirwa JI, Kamya V, Asiimwe A, Kuule JK, Kamya MR, Drakeley C, Dorsey G, Rosenthal PJ, Staedke SG -
Associations between Aminoquinoline Resistance Genotypes and Clinical Presentations of Plasmodium falciparum Infection in Uganda.
Antimicrobial agents and chemotherapy 2020 Cuu G, Asua V, Tukwasibwe S, Nsobya SL, Nanteza A, Kimuda MP, Mpimbaza A, Rosenthal PJ -
Keep Politics out of Funding Decisions for Medical Research and Public Health.
The American journal of tropical medicine and hygiene 2020 Rosenthal PJ, Bausch DG, Goraleski KA, Hill DR, Jacobson JA, John CC, Breman JG -
Nonfasted Liver Stiffness Correlates with Liver Disease Parameters and Portal Hypertension in Pediatric Cholestatic Liver Disease.
Hepatology communications 2020 Shneider BL, Goodrich NP, Ye W, Sawyers C, Molleston JP, Merion RM, Leung DH, Karpen SJ, Kamath BM, Cavallo L, Wang K, Teckman JH, Squires JE, Sundaram SS, Rosenthal P, Romero R, Murray KF, Loomes KM,… -
Progression of Fatty Liver Disease in Children Receiving Standard of Care Lifestyle Advice.
Gastroenterology 2020 Xanthakos SA, Lavine JE, Yates KP, Schwimmer JB, Molleston JP, Rosenthal P, Murray KF, Vos MB, Jain AK, Scheimann AO, Miloh T, Fishbein M, Behling CA, Brunt EM, Sanyal AJ, Tonascia J, NASH Clinical … -
Longitudinal Outcomes in Young Patients with Alpha-1-Antitrypsin Deficiency with Native Liver Reveal that Neonatal Cholestasis is a Poor Predictor of Future Portal Hypertension.
The Journal of pediatrics 2020 Teckman J, Rosenthal P, Hawthorne K, Spino C, Bass LM, Murray KF, Kerkar N, Magee JC, Karpen S, Heubi JE, Molleston JP, Squires RH, Kamath BM, Guthery SL, Loomes KM, Sherker AH, Sokol RJ, ChiLDReN (… -
Hepatic Histology in Treatment-naïve Children With Chronic Hepatitis B Infection Living in the United States and Canada.
Journal of pediatric gastroenterology and nutrition 2020 Rodriguez-Baez N, Murray KF, Kleiner DE, Ling SC, Rosenthal P, Carlin K, Cooper K, Schwarz KB, Schwarzenberg SJ, Teckman JH, Ghany MG, Alawad AS -
Amalgamating Isatin/Indole/Nitroimidazole with 7-chloroquinolines via azide-alkyne cycloaddition: Synthesis, anti-plasmodial, and cytotoxic evaluation.
Chemical biology & drug design 2020 Kumar S, Saini A, Legac J, Rosenthal PJ, Raj R, Kumar V -
Variations in killer-cell immunoglobulin-like receptor and human leukocyte antigen genes and immunity to malaria.
Cellular & molecular immunology 2020 Tukwasibwe S, Nakimuli A, Traherne J, Chazara O, Jayaraman J, Trowsdale J, Moffett A, Jagannathan P, Rosenthal PJ, Cose S, Colucci F -
Perspectives on Battling COVID-19 in Countries of Latin America and the Caribbean.
The American journal of tropical medicine and hygiene 2020 Andrus JK, Evans-Gilbert T, Santos JI, Guzman MG, Rosenthal PJ, Toscano C, Valenzuela MT, Siqueira M, Etienne C, Breman JG -
COVID-19: Shining the Light on Africa.
The American journal of tropical medicine and hygiene 2020 Rosenthal PJ, Breman JG, Djimde AA, John CC, Kamya MR, Leke RGF, Moeti MR, Nkengasong J, Bausch DG -
Determination of piperaquine concentration in human plasma and the correlation of capillary versus venous plasma concentrations.
PloS one 2020 Mwebaza N, Cheah V, Forsman C, Kajubi R, Marzan F, Wallender E, Dorsey G, Rosenthal PJ, Aweeka F, Huang L -
Lead Optimization of Second-Generation Acridones as Broad-Spectrum Antimalarials.
Journal of medicinal chemistry 2020 Kancharla P, Dodean RA, Li Y, Pou S, Pybus B, Melendez V, Read L, Bane CE, Vesely B, Kreishman-Deitrick M, Black C, Li Q, Sciotti RJ, Olmeda R, Luong TL, Gaona H, Potter B, Sousa J, Marcsisin S, … -
Unraveling the Relationship Between Itching, Scratch Scales, and Biomarkers in Children With Alagille Syndrome.
Hepatology communications 2020 Kamath BM, Spino C, McLain R, Magee JC, Fredericks EM, Setchell KD, Miethke A, Molleston JP, Mack CL, Squires RH, Alonso EM, Murray KF, Loomes KM, Kyle Jensen M, Karpen SJ, Rosenthal P, Thomas D, … -
Ombitasvir, Paritaprevir, Ritonavir, and Dasabuvir Mini-Tabs Plus Ribavirin for Children Aged 3-11 Years with Hepatitis C Genotype 1a.
Advances in therapy 2020 Rosenthal P, Narkewicz MR, Yao BB, Jolley CD, Lobritto SJ, Wen J, Molleston JP, Hsu EK, Jonas MM, Zha J, Liu L, Leung DH -
Antimalarial Trioxolanes with Superior Drug-Like Properties and In Vivo Efficacy.
ACS infectious diseases 2020 Blank BR, Gonciarz RL, Talukder P, Gut J, Legac J, Rosenthal PJ, Renslo AR -
The Impact of Control Interventions on Malaria Burden in Young Children in a Historically High-Transmission District of Uganda: A Pooled Analysis of Cohort Studies from 2007 to 2018.
The American journal of tropical medicine and hygiene 2020 Kamya MR, Kakuru A, Muhindo M, Arinaitwe E, Nankabirwa JI, Rek J, Bigira V, Kapisi J, Wanzira H, Achan J, Natureeba P, Gasasira A, Havlir D, Jagannathan P, Rosenthal PJ, Rodriguez-Barraquer I, Dorsey … -
The Importance of Diagnostic Testing during a Viral Pandemic: Early Lessons from Novel Coronavirus Disease (COVID-19).
The American journal of tropical medicine and hygiene 2020 Rosenthal PJ -
The impact of antimalarial resistance on the genetic structure of Plasmodium falciparum in the DRC.
Nature communications 2020 Verity R, Aydemir O, Brazeau NF, Watson OJ, Hathaway NJ, Mwandagalirwa MK, Marsh PW, Thwai K, Fulton T, Denton M, Morgan AP, Parr JB, Tumwebaze PK, Conrad M, Rosenthal PJ, Ishengoma DS, Ngondi J, … -
Are three drugs for malaria better than two?
Lancet (London, England) 2020 Rosenthal PJ -
Improved Outcomes for Liver Transplantation in Patients with Biliary Atresia Since Pediatric End-Stage Liver Disease Implementation: Analysis of the Society of Pediatric Liver Transplantation Registry.
The Journal of pediatrics 2020 Taylor SA, Venkat V, Arnon R, Gopalareddy VV, Rosenthal P, Erinjeri J, Anand R, Daniel JF, Society of Pediatric Liver Transplantation -
Plasmodium falciparum Resistance to a Lead Benzoxaborole Due to Blocked Compound Activation and Altered Ubiquitination or Sumoylation.
mBio 2020 Sindhe KMV, Wu W, Legac J, Zhang YK, Easom EE, Cooper RA, Plattner JJ, Freund YR, DeRisi JL, Rosenthal PJ -
Outcomes of Childhood Cholestasis in Alagille Syndrome: Results of a Multicenter Observational Study.
Hepatology communications 2020 Kamath BM, Ye W, Goodrich NP, Loomes KM, Romero R, Heubi JE, Leung DH, Spinner NB, Piccoli DA, Alonso EM, Guthery SL, Karpen SJ, Mack CL, Molleston JP, Murray KF, Rosenthal P, Squires JE, Teckman J, … -
Associations between red blood cell variants and malaria among children and adults from three areas of Uganda: a prospective cohort study.
Malaria journal 2020 Kakande E, Greenhouse B, Bajunirwe F, Drakeley C, Nankabirwa JI, Walakira A, Nsobya SL, Katureebe A, Rek J, Arinaitwe E, Rosenthal PJ, Kamya MR, Dorsey G, Rodriguez-Barraquer I -
Falcipain cysteine proteases of malaria parasites: An update.
Biochimica et biophysica acta. Proteins and proteomics 2020 Rosenthal PJ -
Functionalized Naphthalimide-4-aminoquinoline Conjugates as Promising Antiplasmodials, with Mechanistic Insights.
ACS medicinal chemistry letters 2020 Legac J, Adeniyi AA, Kisten P, Rosenthal PJ, Singh P, Kumar V -
Neurodevelopmental Outcomes in Preschool and School Aged Children With Biliary Atresia and Their Native Liver.
Journal of pediatric gastroenterology and nutrition 2020 Squires JE, Ng VL, Hawthorne K, Henn LL, Sorensen LG, Fredericks EM, Alonso EM, Murray KF, Loomes KM, Karpen SJ, Cavallo LA, Molleston JP, Bezerra JA, Rosenthal P, Squires RH, Wang KS, Schwarz KB, … -
Coupling the Antimalarial Cell Penetrating Peptide TP10 to Classical Antimalarial Drugs Primaquine and Chloroquine Produces Strongly Hemolytic Conjugates.
Molecules (Basel, Switzerland) 2019 Aguiar L, Biosca A, Lantero E, Gut J, Vale N, Rosenthal PJ, Nogueira F, Andreu D, Fernàndez-Busquets X, Gomes P -
Design, synthesis, heme binding and density functional theory studies of isoindoline-dione-4-aminoquinolines as potential antiplasmodials.
Future medicinal chemistry 2019 Rani A, Kumar S, Legac J, Adeniyi AA, Awolade P, Singh P, Rosenthal PJ, Kumar V -
Biannual versus annual mass azithromycin distribution and malaria seroepidemiology among preschool children in Niger: a sub-study of a cluster randomized trial.
Malaria journal 2019 Oldenburg CE, Amza A, Cooley G, Kadri B, Nassirou B, Arnold BF, Rosenthal PJ, O'Brien KS, West SK, Bailey RL, Porco TC, Keenan JD, Lietman TM, Martin DL -
Distinct Biomarker Profiles Distinguish Malawian Children with Malarial and Non-malarial Sepsis.
The American journal of tropical medicine and hygiene 2019 Kortz TB, Nyirenda J, Tembo D, Elfving K, Baltzell K, Bandawe G, Rosenthal PJ, Macfarlane SB, Mandala W, Nyirenda TS -
Malaria parasites fine-tune mutations to resist drugs.
Nature 2019 Tilley L, Rosenthal PJ -
Synthesis, anti-plasmodial and cytotoxic evaluation of 1H-1,2,3-triazole/acyl hydrazide integrated tetrahydro-β-carboline-4-aminoquinoline conjugates.
Bioorganic & medicinal chemistry letters 2019 Sharma B, Kaur S, Legac J, Rosenthal PJ, Kumar V -
Be Careful What You Eat!
The American journal of tropical medicine and hygiene 2019 Rosenthal PJ -
Phenotypes of Chronic Hepatitis B in Children From a Large North American Cohort.
Journal of pediatric gastroenterology and nutrition 2019 Schwarz KB, Lombardero M, Di Bisceglie AM, Murray KF, Rosenthal P, Ling SC, Cloonan YK, Rodriguez-Baez N, Schwarzenberg SJ, Hoofnagle JH, Teckman J, Hepatitis B Research Network (HBRN) -
[(7-chloroquinolin-4-yl)amino]acetophenones and their copper(II) derivatives: Synthesis, characterization, computational studies and antimalarial activity.
EXCLI journal 2019 de J Parra Y, Andueza L FD, Ferrer M RE, Bruno Colmenarez J, Acosta ME, Charris J, Rosenthal PJ, Gut J -
The Diversity of the Plasmodium falciparum K13 Propeller Domain Did Not Increase after Implementation of Artemisinin-Based Combination Therapy in Uganda.
Antimicrobial agents and chemotherapy 2019 Conrad MD, Nsobya SL, Rosenthal PJ -
Artemisinin Resistance in Eastern India.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2019 Rosenthal PJ -
Has Rotavirus Vaccination Decreased the Prevalence of Biliary Atresia?
Journal of clinical gastroenterology 2019 Danial E, Fleck-Derderian S, Rosenthal P -
A Prospective Trial of Withdrawal and Reinstitution of Ursodeoxycholic Acid in Pediatric Primary Sclerosing Cholangitis.
Hepatology communications 2019 Black DD, Mack C, Kerkar N, Miloh T, Sundaram SS, Anand R, Gupta A, Alonso E, Arnon R, Bulut P, Karpen S, Lin CH, Rosenthal P, Ryan M, Squires RH, Valentino P, Elsea SH, Shneider BL -
Ledipasvir-Sofosbuvir for 12 Weeks in Children 3 to <6 Years Old With Chronic Hepatitis C.
Hepatology (Baltimore, Md.) 2019 Schwarz KB, Rosenthal P, Murray KF, Honegger JR, Hardikar W, Hague R, Mittal N, Massetto B, Brainard DM, Hsueh CH, Shao J, Parhy B, Narkewicz MR, Rao GS, Whitworth S, Bansal S, Balistreri WF -
Sofosbuvir and Ribavirin Therapy for Children Aged 3 to <12 Years With Hepatitis C Virus Genotype 2 or 3 Infection.
Hepatology (Baltimore, Md.) 2019 Rosenthal P, Schwarz KB, Gonzalez-Peralta RP, Lin CH, Kelly DA, Nightingale S, Balistreri WF, Bansal S, Jonas MM, Massetto B, Brainard DM, Hsueh CH, Shao J, Parhy B, Davison S, Feiterna-Sperling C, … -
Antimalarial drug resistance in Africa: the calm before the storm?
The Lancet. Infectious diseases 2019 Conrad MD, Rosenthal PJ -
Reduced Exposure to Piperaquine, Compared to Adults, in Young Children Receiving Dihydroartemisinin-Piperaquine as Malaria Chemoprevention.
Clinical pharmacology and therapeutics 2019 Whalen ME, Kajubi R, Chamankhah N, Huang L, Orukan F, Wallender E, Kamya MR, Dorsey G, Jagannathan P, Rosenthal PJ, Mwebaza N, Aweeka FT -
A shorter course for anti-relapse therapy against vivax malaria.
Lancet (London, England) 2019 Rosenthal PJ -
Mass Drug Administration to Control and Eliminate Malaria in Africa: How Do We Best Utilize the Tools at Hand?
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2019 Guler JL, Rosenthal PJ -
Identification of a potent benzoxaborole drug candidate for treating cryptosporidiosis.
Nature communications 2019 Lunde CS, Stebbins EE, Jumani RS, Hasan MM, Miller P, Barlow J, Freund YR, Berry P, Stefanakis R, Gut J, Rosenthal PJ, Love MS, McNamara CW, Easom E, Plattner JJ, Jacobs RT, Huston CD -
Biannual mass azithromycin distributions and malaria parasitemia in pre-school children in Niger: A cluster-randomized, placebo-controlled trial.
PLoS medicine 2019 Arzika AM, Maliki R, Boubacar N, Kane S, Cotter SY, Lebas E, Cook C, Bailey RL, West SK, Rosenthal PJ, Porco TC, Lietman TM, Keenan JD, MORDOR Study Group -
Improvement of Asparagine Ethylenediamines as Anti-malarial Plasmodium-Selective Proteasome Inhibitors.
Journal of medicinal chemistry 2019 Zhan W, Visone J, Ouellette T, Harris JC, Wang R, Zhang H, Singh PK, Ginn J, Sukenick G, Wong TT, Okoro JI, Scales RM, Tumwebaze PK, Rosenthal PJ, Kafsack BFC, Cooper RA, Meinke PT, Kirkman LA, Lin G -
Metagenomic next-generation sequencing of samples from pediatric febrile illness in Tororo, Uganda.
PloS one 2019 Ramesh A, Nakielny S, Hsu J, Kyohere M, Byaruhanga O, de Bourcy C, Egger R, Dimitrov B, Juan YF, Sheu J, Wang J, Kalantar K, Langelier C, Ruel T, Mpimbaza A, Wilson MR, Rosenthal PJ, DeRisi JL -
Understanding the context of delays in seeking appropriate care for children with symptoms of severe malaria in Uganda.
PloS one 2019 Mpimbaza A, Nayiga S, Ndeezi G, Rosenthal PJ, Karamagi C, Katahoire A -
Expanded Availability of Intravenous Artesunate for the Treatment of Severe Malaria in the United States.
The American journal of tropical medicine and hygiene 2019 Rosenthal PJ, Tan KR -
Falcipain Inhibitors Based on the Natural Product Gallinamide A Are Potent in Vitro and in Vivo Antimalarials.
Journal of medicinal chemistry 2019 Stoye A, Juillard A, Tang AH, Legac J, Gut J, White KL, Charman SA, Rosenthal PJ, Grau GER, Hunt NH, Payne RJ -
Age, race and viral genotype are associated with the prevalence of hepatitis B e antigen in children and adults with chronic hepatitis B.
Journal of viral hepatitis 2019 Di Bisceglie AM, King WC, Lisker-Melman M, Khalili M, Belle SH, Feld JJ, Ghany MG, Janssen HLA, Lau D, Lee WM, Ling SC, Cooper S, Rosenthal P, Schwarz KB, Sterling RK, Teckman JH, Terrault N, … -
Substituted 1,3-dioxoisoindoline-4-aminoquinolines coupled via amide linkers: Synthesis, antiplasmodial and cytotoxic evaluation.
Bioorganic chemistry 2019 Rani A, Legac J, Rosenthal PJ, Kumar V -
Identification of Polycystic Kidney Disease 1 Like 1 Gene Variants in Children With Biliary Atresia Splenic Malformation Syndrome.
Hepatology (Baltimore, Md.) 2019 Berauer JP, Mezina AI, Okou DT, Sabo A, Muzny DM, Gibbs RA, Hegde MR, Chopra P, Cutler DJ, Perlmutter DH, Bull LN, Thompson RJ, Loomes KM, Spinner NB, Rajagopalan R, Guthery SL, Moore B, Yandell M, … -
Comparative Efficacy of Artemether-Lumefantrine and Dihydroartemisinin-Piperaquine for the Treatment of Uncomplicated Malaria in Ugandan Children.
The Journal of infectious diseases 2019 Yeka A, Wallender E, Mulebeke R, Kibuuka A, Kigozi R, Bosco A, Kyambadde P, Opigo J, Kalyesubula S, Senzoga J, Vinden J, Conrad M, Rosenthal PJ -
Persistent Parasitemia Despite Dramatic Reduction in Malaria Incidence After 3 Rounds of Indoor Residual Spraying in Tororo, Uganda.
The Journal of infectious diseases 2019 Nankabirwa JI, Briggs J, Rek J, Arinaitwe E, Nayebare P, Katrak S, Staedke SG, Rosenthal PJ, Rodriguez-Barraquer I, Kamya MR, Dorsey G, Greenhouse B -
Changing Molecular Markers of Antimalarial Drug Sensitivity across Uganda.
Antimicrobial agents and chemotherapy 2019 Asua V, Vinden J, Conrad MD, Legac J, Kigozi SP, Kamya MR, Dorsey G, Nsobya SL, Rosenthal PJ -
Combination of Entecavir/Peginterferon Alfa-2a in Children With Hepatitis B e Antigen-Positive Immune Tolerant Chronic Hepatitis B Virus Infection.
Hepatology (Baltimore, Md.) 2019 Rosenthal P, Ling SC, Belle SH, Murray KF, Rodriguez-Baez N, Schwarzenberg SJ, Teckman J, Lin HS, Schwarz KB, Hepatitis B Research Network (HBRN) -
Malaria: How Are We Doing and How Can We Do Better?
The American journal of tropical medicine and hygiene 2019 Rosenthal PJ, John CC, Rabinovich NR -
Modeling Prevention of Malaria and Selection of Drug Resistance with Different Dosing Schedules of Dihydroartemisinin-Piperaquine Preventive Therapy during Pregnancy in Uganda.
Antimicrobial agents and chemotherapy 2019 Wallender E, Zhang N, Conrad M, Kakuru A, Muhindo M, Tumwebaze P, Kajubi R, Mota D, Legac J, Jagannathan P, Havlir D, Kamya M, Dorsey G, Aweeka F, Rosenthal PJ, Savic RM -
Optimal dosing of dihydroartemisinin-piperaquine for seasonal malaria chemoprevention in young children.
Nature communications 2019 Chotsiri P, Zongo I, Milligan P, Compaore YD, Somé AF, Chandramohan D, Hanpithakpong W, Nosten F, Greenwood B, Rosenthal PJ, White NJ, Ouédraogo JB, Tarning J -
Center variation in screening for and management of metabolic syndrome in pediatric liver transplant recipients: A survey of SPLIT centers.
Pediatric transplantation 2019 Hilk K, Zerofsky M, Rhee S, Rosenthal P, Perito ER -
Association Between Recent Overnight Travel and Risk of Malaria: A Prospective Cohort Study at 3 Sites in Uganda.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2019 Arinaitwe E, Dorsey G, Nankabirwa JI, Kigozi SP, Katureebe A, Kakande E, Rek J, Rosenthal PJ, Drakeley C, Kamya MR, Staedke SG -
Diet and Exercise in Pediatric Liver Transplant Recipients: Behaviors and Association With Metabolic Syndrome.
Journal of pediatric gastroenterology and nutrition 2019 Chambers JH, Zerofsky M, Lustig RH, Rosenthal P, Perito ER -
Volume 100 of the American Journal of Tropical Medicine and Hygiene.
The American journal of tropical medicine and hygiene 2019 Rosenthal PJ, Vinetz JM, Siegel C, Kazura JW -
Bone Density in Children With Chronic Liver Disease Correlates With Growth and Cholestasis.
Hepatology (Baltimore, Md.) 2018 Loomes KM, Spino C, Goodrich NP, Hangartner TN, Marker AE, Heubi JE, Kamath BM, Shneider BL, Rosenthal P, Hertel PM, Karpen SJ, Molleston JP, Murray KF, Schwarz KB, Squires RH, Teckman J, Turmelle YP,… -
Caregiver responses and association with delayed care-seeking in children with uncomplicated and severe malaria.
Malaria journal 2018 Mpimbaza A, Katahoire A, Rosenthal PJ, Karamagi C, Ndeezi G -
Artemisinin Resistance Outside of Southeast Asia.
The American journal of tropical medicine and hygiene 2018 Rosenthal PJ -
Safety and Efficacy of Ledipasvir-Sofosbuvir With or Without Ribavirin for Chronic Hepatitis C in Children Ages 6-11.
Hepatology (Baltimore, Md.) 2018 Murray KF, Balistreri WF, Bansal S, Whitworth S, Evans HM, Gonzalez-Peralta RP, Wen J, Massetto B, Kersey K, Shao J, Garrison KL, Parhy B, Brainard DM, Arnon R, Gillis LA, Jonas MM, Lin CH, Narkewicz … -
Advances in Pediatric Hepatology.
Clinics in liver disease 2018 Rosenthal P -
Ombitasvir/Paritaprevir/Ritonavir With or Without Dasabuvir and With or Without Ribavirin for Adolescents With HCV Genotype 1 or 4.
Hepatology communications 2018 Leung DH, Wirth S, Yao BB, Viani RM, Gonzalez-Peralta RP, Jonas MM, Lobritto SJ, Narkewicz MR, Sokal E, Fortuny C, Hsu EK, Del Valle-Segarra A, Zha J, Larsen L, Liu L, Shuster DL, Cohen DE, Rosenthal … -
Placebo-Controlled Randomized Trial of an Intestinal Bile Salt Transport Inhibitor for Pruritus in Alagille Syndrome.
Hepatology communications 2018 Shneider BL, Spino C, Kamath BM, Magee JC, Bass LM, Setchell KD, Miethke A, Molleston JP, Mack CL, Squires RH, Murray KF, Loomes KM, Rosenthal P, Karpen SJ, Leung DH, Guthery SL, Thomas D, Sherker AH,… -
Impact of Steroid Therapy on Early Growth in Infants with Biliary Atresia: The Multicenter Steroids in Biliary Atresia Randomized Trial.
The Journal of pediatrics 2018 Alonso EM, Ye W, Hawthorne K, Venkat V, Loomes KM, Mack CL, Hertel PM, Karpen SJ, Kerkar N, Molleston JP, Murray KF, Romero R, Rosenthal P, Schwarz KB, Shneider BL, Suchy FJ, Turmelle YP, Wang KS, … -
Molecular assays for antimalarial drug resistance surveillance: A target product profile.
PloS one 2018 Nsanzabana C, Ariey F, Beck HP, Ding XC, Kamau E, Krishna S, Legrand E, Lucchi N, Miotto O, Nag S, Noedl H, Roper C, Rosenthal PJ, Schallig HDFH, Taylor SM, Volkman SK, Gonzalez IJ -
Associations between erythrocyte polymorphisms and risks of uncomplicated and severe malaria in Ugandan children: A case control study.
PloS one 2018 Mpimbaza A, Walakira A, Ndeezi G, Katahoire A, Karamagi C, Nsobya SL, Tukwasibwe S, Asua V, Rosenthal PJ -
Intermittent Preventive Treatment for Malaria in Pregnancy: Optimization of Target Concentrations of Dihydroartemisinin-Piperaquine.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2018 Savic RM, Jagannathan P, Kajubi R, Huang L, Zhang N, Were M, Kakuru A, Muhindo MK, Mwebaza N, Wallender E, Clark TD, Opira B, Kamya M, Havlir DV, Rosenthal PJ, Dorsey G, Aweeka FT -
Cysteine proteases in protozoan parasites.
PLoS neglected tropical diseases 2018 Siqueira-Neto JL, Debnath A, McCall LI, Bernatchez JA, Ndao M, Reed SL, Rosenthal PJ -
Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance.
Proceedings of the National Academy of Sciences of the United States of America 2018 Kirkman LA, Zhan W, Visone J, Dziedziech A, Singh PK, Fan H, Tong X, Bruzual I, Hara R, Kawasaki M, Imaeda T, Okamoto R, Sato K, Michino M, Alvaro EF, Guiang LF, Sanz L, Mota DJ, Govindasamy K, Wang R… -
Plasmodium falciparum Falcipain-2a Polymorphisms in Southeast Asia and Their Association With Artemisinin Resistance.
The Journal of infectious diseases 2018 Siddiqui FA, Cabrera M, Wang M, Brashear A, Kemirembe K, Wang Z, Miao J, Chookajorn T, Yang Z, Cao Y, Dong G, Rosenthal PJ, Cui L -
Reconciling Conflicting Results From Pediatric Sepsis Studies: The Need for Context-Specific Sepsis Bundles.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2018 Kortz T, Rosenthal PJ -
De novo formation of the biliary system by TGFβ-mediated hepatocyte transdifferentiation.
Nature 2018 Schaub JR, Huppert KA, Kurial SNT, Hsu BY, Cast AE, Donnelly B, Karns RA, Chen F, Rezvani M, Luu HY, Mattis AN, Rougemont AL, Rosenthal P, Huppert SS, Willenbring H -
A Learning Collaborative Approach Increases Specificity of Diagnosis of Acute Liver Failure in Pediatric Patients.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2018 Narkewicz MR, Horslen S, Hardison RM, Shneider BL, Rodriguez-Baez N, Alonso EM, Ng VL, Leonis MA, Loomes KM, Rudnick DA, Rosenthal P, Romero R, Subbarao GC, Li R, Belle SH, Squires RH, Pediatric Acute… -
Clinically Actionable Hypercholesterolemia and Hypertriglyceridemia in Children with Nonalcoholic Fatty Liver Disease.
The Journal of pediatrics 2018 Harlow KE, Africa JA, Wells A, Belt PH, Behling CA, Jain AK, Molleston JP, Newton KP, Rosenthal P, Vos MB, Xanthakos SA, Lavine JE, Schwimmer JB, Nonalcoholic Steatohepatitis Clinical Research Network… -
Outcomes of surgical management of familial intrahepatic cholestasis 1 and bile salt export protein deficiencies.
Hepatology communications 2018 Bull LN, Pawlikowska L, Strautnieks S, Jankowska I, Czubkowski P, Dodge JL, Emerick K, Wanty C, Wali S, Blanchard S, Lacaille F, Byrne JA, van Eerde AM, Kolho KL, Houwen R, Lobritto S, Hupertz V, … -
An OX40/OX40L interaction directs successful immunity to hepatitis B virus.
Science translational medicine 2018 Publicover J, Gaggar A, Jespersen JM, Halac U, Johnson AJ, Goodsell A, Avanesyan L, Nishimura SL, Holdorf M, Mansfield KG, Judge JB, Koshti A, Croft M, Wakil AE, Rosenthal P, Pai E, Cooper S, Baron JL -
Neurodevelopmental Outcome of Young Children with Biliary Atresia and Native Liver: Results from the ChiLDReN Study.
The Journal of pediatrics 2018 Ng VL, Sorensen LG, Alonso EM, Fredericks EM, Ye W, Moore J, Karpen SJ, Shneider BL, Molleston JP, Bezerra JA, Murray KF, Loomes KM, Rosenthal P, Squires RH, Wang K, Arnon R, Schwarz KB, Turmelle YP, … -
Predicting Optimal Dihydroartemisinin-Piperaquine Regimens to Prevent Malaria During Pregnancy for Human Immunodeficiency Virus-Infected Women Receiving Efavirenz.
The Journal of infectious diseases 2018 Wallender E, Vucicevic K, Jagannathan P, Huang L, Natureeba P, Kakuru A, Muhindo M, Nakalembe M, Havlir D, Kamya M, Aweeka F, Dorsey G, Rosenthal PJ, Savic RM -
Endoperoxide-8-aminoquinoline hybrids as dual-stage antimalarial agents with enhanced metabolic stability.
European journal of medicinal chemistry 2018 Capela R, Magalhães J, Miranda D, Machado M, Sanches-Vaz M, Albuquerque IS, Sharma M, Gut J, Rosenthal PJ, Frade R, Perry MJ, Moreira R, Prudêncio M, Lopes F -
Clinical consequences of submicroscopic malaria parasitaemia in Uganda.
Malaria journal 2018 Katrak S, Nayebare P, Rek J, Arinaitwe E, Nankabirwa JI, Kamya M, Dorsey G, Rosenthal PJ, Greenhouse B -
Bisphenol a increases risk for presumed non-alcoholic fatty liver disease in Hispanic adolescents in NHANES 2003-2010.
Environmental health : a global access science source 2018 Verstraete SG, Wojcicki JM, Perito ER, Rosenthal P -
Health-related Quality of Life in Adolescent Patients With Hepatitis C Genotype 1 Treated With Sofosbuvir and Ledipasvir.
Journal of pediatric gastroenterology and nutrition 2018 Younossi ZM, Stepanova M, Balistreri W, Schwarz K, Murray KF, Rosenthal P, Bansal S, Hunt S -
Subclinical Atherosclerosis in Pediatric Liver Transplant Recipients: Carotid and Aorta Intima-Media Thickness and Their Predictors.
The Journal of pediatrics 2017 Perito ER, Phelps A, Vase T, Feldstein VA, Lustig RH, Rosenthal P -
"The Way We Were" Ken Warren's Legacy and Modern Investments in Global Health.
The American journal of tropical medicine and hygiene 2017 Dunavan CP, Rosenthal PJ -
Changing Antimalarial Drug Sensitivities in Uganda.
Antimicrobial agents and chemotherapy 2017 Rasmussen SA, Ceja FG, Conrad MD, Tumwebaze PK, Byaruhanga O, Katairo T, Nsobya SL, Rosenthal PJ, Cooper RA -
Microwave-promoted facile access to 4-aminoquinoline-phthalimides: Synthesis and anti-plasmodial evaluation.
European journal of medicinal chemistry 2017 Rani A, Singh A, Gut J, Rosenthal PJ, Kumar V -
Impact of Intermittent Preventive Treatment During Pregnancy on Plasmodium falciparum Drug Resistance-Mediating Polymorphisms in Uganda.
The Journal of infectious diseases 2017 Conrad MD, Mota D, Foster M, Tukwasibwe S, Legac J, Tumwebaze P, Whalen M, Kakuru A, Nayebare P, Wallender E, Havlir DV, Jagannathan P, Huang L, Aweeka F, Kamya MR, Dorsey G, Rosenthal PJ -
Comparative Prevalence of Plasmodium falciparum Resistance-Associated Genetic Polymorphisms in Parasites Infecting Humans and Mosquitoes in Uganda.
The American journal of tropical medicine and hygiene 2017 Conrad MD, Mota D, Musiime A, Kilama M, Rek J, Kamya M, Dorsey G, Rosenthal PJ -
Demographic, Socioeconomic, and Geographic Factors Leading to Severe Malaria and Delayed Care Seeking in Ugandan Children: A Case-Control Study.
The American journal of tropical medicine and hygiene 2017 Mpimbaza A, Ndeezi G, Katahoire A, Rosenthal PJ, Karamagi C -
Performance of Loop-Mediated Isothermal Amplification for the Identification of Submicroscopic Plasmodium falciparum Infection in Uganda.
The American journal of tropical medicine and hygiene 2017 Katrak S, Murphy M, Nayebare P, Rek J, Smith M, Arinaitwe E, Nankabirwa JI, Kamya M, Dorsey G, Rosenthal PJ, Greenhouse B -
Marked variation in prevalence of malaria-protective human genetic polymorphisms across Uganda.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2017 Walakira A, Tukwasibwe S, Kiggundu M, Verra F, Kakeeto P, Ruhamyankaka E, Drakeley C, Dorsey G, Kamya MR, Nsobya SL, Rosenthal PJ -
Let's Eliminate Diseases, Not Institutes: The Case for the Fogarty International Center.
The American journal of tropical medicine and hygiene 2017 Rosenthal PJ, Goraleski KA, Rabinovich NR, Walker PF -
Plasmodium Species Infecting Children Presenting with Malaria in Uganda.
The American journal of tropical medicine and hygiene 2017 Asua V, Tukwasibwe S, Conrad M, Walakira A, Nankabirwa JI, Mugenyi L, Kamya MR, Nsobya SL, Rosenthal PJ -
Sofosbuvir and ribavirin in adolescents 12-17 years old with hepatitis C virus genotype 2 or 3 infection.
Hepatology (Baltimore, Md.) 2017 Wirth S, Rosenthal P, Gonzalez-Peralta RP, Jonas MM, Balistreri WF, Lin CH, Hardikar W, Kersey K, Massetto B, Kanwar B, Brainard DM, Shao J, Svarovskaia E, Kirby B, Arnon R, Murray KF, Schwarz KB -
Pediatric liver failure: we came, we saw, but have we conquered?
F1000Research 2017 Smith SK, Rosenthal P -
Development of Novel Peptide-Based Michael Acceptors Targeting Rhodesain and Falcipain-2 for the Treatment of Neglected Tropical Diseases (NTDs).
Journal of medicinal chemistry 2017 Previti S, Ettari R, Cosconati S, Amendola G, Chouchene K, Wagner A, Hellmich UA, Ulrich K, Krauth-Siegel RL, Wich PR, Schmid I, Schirmeister T, Gut J, Rosenthal PJ, Grasso S, Zappalà M -
The Relative Effects of Artemether-lumefantrine and Non-artemisinin Antimalarials on Gametocyte Carriage and Transmission of Plasmodium falciparum: A Systematic Review and Meta-analysis.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2017 Ippolito MM, Johnson J, Mullin C, Mallow C, Morgan N, Wallender E, Li T, Rosenthal PJ -
4-Aminoquinoline-chalcone/-N-acetylpyrazoline conjugates: Synthesis and antiplasmodial evaluation.
European journal of medicinal chemistry 2017 Kumar S, Saini A, Gut J, Rosenthal PJ, Raj R, Kumar V -
Mass Azithromycin and Malaria Parasitemia in Niger: Results from a Community-Randomized Trial.
The American journal of tropical medicine and hygiene 2017 O'Brien KS, Cotter SY, Amza A, Kadri B, Nassirou B, Stoller NE, Zhou Z, Cotter C, West SK, Bailey RL, Rosenthal PJ, Gaynor BD, Porco TC, Lietman TM -
Association Between Cytokines and Liver Histology in Children with Nonalcoholic Fatty Liver Disease.
Hepatology communications 2017 Perito ER, Ajmera V, Bass NM, Rosenthal P, Lavine JE, Schwimmer JB, Yates KP, Diehl AM, Molleston JP, Murray KF, Scheimann A, Gill R, Glidden D, Aouizerat B -
Enantioselective Synthesis and in Vivo Evaluation of Regioisomeric Analogues of the Antimalarial Arterolane.
Journal of medicinal chemistry 2017 Blank BR, Gut J, Rosenthal PJ, Renslo AR -
Hepatic steatosis after pediatric liver transplant.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2017 Perito ER, Vase T, Ramachandran R, Phelps A, Jen KY, Lustig RH, Feldstein VA, Rosenthal P -
Benzoxaborole Antimalarial Agents. Part 5. Lead Optimization of Novel Amide Pyrazinyloxy Benzoxaboroles and Identification of a Preclinical Candidate.
Journal of medicinal chemistry 2017 Zhang YK, Plattner JJ, Easom EE, Jacobs RT, Guo D, Freund YR, Berry P, Ciaravino V, Erve JCL, Rosenthal PJ, Campo B, Gamo FJ, Sanz LM, Cao J -
Shorter Leukocyte Telomere Length in Relation to Presumed Nonalcoholic Fatty Liver Disease in Mexican-American Men in NHANES 1999-2002.
International journal of hepatology 2017 Wojcicki JM, Rehkopf D, Epel E, Rosenthal P -
The safety and effectiveness of ledipasvir-sofosbuvir in adolescents 12-17 years old with hepatitis C virus genotype 1 infection.
Hepatology (Baltimore, Md.) 2017 Balistreri WF, Murray KF, Rosenthal P, Bansal S, Lin CH, Kersey K, Massetto B, Zhu Y, Kanwar B, German P, Svarovskaia E, Brainard DM, Wen J, Gonzalez-Peralta RP, Jonas MM, Schwarz K -
Initial assessment of the infant with neonatal cholestasis-Is this biliary atresia?
PloS one 2017 Shneider BL, Moore J, Kerkar N, Magee JC, Ye W, Karpen SJ, Kamath BM, Molleston JP, Bezerra JA, Murray KF, Loomes KM, Whitington PF, Rosenthal P, Squires RH, Guthery SL, Arnon R, Schwarz KB, Turmelle … -
Health-related Quality of Life in Pediatric Patients With Chronic Hepatitis B Living in the United States and Canada.
Journal of pediatric gastroenterology and nutrition 2017 Schwarzenberg SJ, Ling SC, Cloonan YK, Lin HS, Evon DM, Murray KF, Rodriguez-Baez N, Rosenthal P, Teckman J, Schwarz KB, Hepatitis B Research Network -
Piperazine-linked 4-aminoquinoline-chalcone/ferrocenyl-chalcone conjugates: Synthesis and antiplasmodial evaluation.
Chemical biology & drug design 2017 Singh A, Rani A, Gut J, Rosenthal PJ, Kumar V -
Analysis of surgical interruption of the enterohepatic circulation as a treatment for pediatric cholestasis.
Hepatology (Baltimore, Md.) 2017 Wang KS, Tiao G, Bass LM, Hertel PM, Mogul D, Kerkar N, Clifton M, Azen C, Bull L, Rosenthal P, Stewart D, Superina R, Arnon R, Bozic M, Brandt ML, Dillon PA, Fecteau A, Iyer K, Kamath B, Karpen S, … -
Drug resistance mediating Plasmodium falciparum polymorphisms and clinical presentations of parasitaemic children in Uganda.
Malaria journal 2017 Tukwasibwe S, Tumwebaze P, Conrad M, Arinaitwe E, Kamya MR, Dorsey G, Nsobya SL, Greenhouse B, Rosenthal PJ -
A potent antimalarial benzoxaborole targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue.
Nature communications 2017 Sonoiki E, Ng CL, Lee MC, Guo D, Zhang YK, Zhou Y, Alley MR, Ahyong V, Sanz LM, Lafuente-Monasterio MJ, Dong C, Schupp PG, Gut J, Legac J, Cooper RA, Gamo FJ, DeRisi J, Freund YR, Fidock DA, Rosenthal… -
Targeting Toxoplasma gondii CPSF3 as a new approach to control toxoplasmosis.
EMBO molecular medicine 2017 Palencia A, Bougdour A, Brenier-Pinchart MP, Touquet B, Bertini RL, Sensi C, Gay G, Vollaire J, Josserand V, Easom E, Freund YR, Pelloux H, Rosenthal PJ, Cusack S, Hakimi MA -
Changing Antimalarial Drug Resistance Patterns Identified by Surveillance at Three Sites in Uganda.
The Journal of infectious diseases 2017 Tumwebaze P, Tukwasibwe S, Taylor A, Conrad M, Ruhamyankaka E, Asua V, Walakira A, Nankabirwa J, Yeka A, Staedke SG, Greenhouse B, Nsobya SL, Kamya MR, Dorsey G, Rosenthal PJ -
Avidity of anti-malarial antibodies inversely related to transmission intensity at three sites in Uganda.
Malaria journal 2017 Ssewanyana I, Arinaitwe E, Nankabirwa JI, Yeka A, Sullivan R, Kamya MR, Rosenthal PJ, Dorsey G, Mayanja-Kizza H, Drakeley C, Greenhouse B, Tetteh KK -
Prevalence and Significance of Autoantibodies in Children With Acute Liver Failure.
Journal of pediatric gastroenterology and nutrition 2017 Narkewicz MR, Horslen S, Belle SH, Rudnick DA, Ng VL, Rosenthal P, Romero R, Loomes KM, Zhang S, Hardison RM, Squires RH, Pediatric Acute Liver Failure Study Group -
Evidence-Based Policies on Migration and Global Health are Essential to Maintain the Health of Those Inside and Outside the United States.
The American journal of tropical medicine and hygiene 2017 Rosenthal PJ, Bausch DG, Higgs S, Rabinovich NR, Hill DR, Plowe CV, Goraleski KA, Walker PF -
Prediabetes in Pediatric Recipients of Liver Transplant: Mechanism and Risk Factors.
The Journal of pediatrics 2016 Perito ER, Lustig RH, Rosenthal P -
Altered Plasmodium falciparum Sensitivity to the Antiretroviral Protease Inhibitor Lopinavir Associated with Polymorphisms in pfmdr1.
Antimicrobial agents and chemotherapy 2016 Sonoiki E, Nsanzabana C, Legac J, Sindhe KM, DeRisi J, Rosenthal PJ -
Measures of Malaria Burden after Long-Lasting Insecticidal Net Distribution and Indoor Residual Spraying at Three Sites in Uganda: A Prospective Observational Study.
PLoS medicine 2016 Katureebe A, Zinszer K, Arinaitwe E, Rek J, Kakande E, Charland K, Kigozi R, Kilama M, Nankabirwa J, Yeka A, Mawejje H, Mpimbaza A, Katamba H, Donnelly MJ, Rosenthal PJ, Drakeley C, Lindsay SW, … -
The (International) American Society of Tropical Medicine and Hygiene.
The American journal of tropical medicine and hygiene 2016 Rosenthal PJ, Hill DR, Bausch DG, Goraleski KA, Higgs S, Walker PF, Plowe CV -
Clearance of Hepatitis C Virus After Fixed-Dose Combination Ledipasvir/Sofosbuvir in an Adolescent Female With Decompensated Cirrhosis.
Journal of pediatric gastroenterology and nutrition 2016 Smith SK, Rosenthal P -
Artemether-Lumefantrine and Dihydroartemisinin-Piperaquine Exert Inverse Selective Pressure on Plasmodium Falciparum Drug Sensitivity-Associated Haplotypes in Uganda.
Open forum infectious diseases 2016 Taylor AR, Flegg JA, Holmes CC, Guérin PJ, Sibley CH, Conrad MD, Dorsey G, Rosenthal PJ -
Ultrasound elastography: is there a shear wave speed cutoff for pediatric liver fibrosis and inflammation?
Clinical imaging 2016 Phelps A, Ramachandran R, Courtier J, Perito E, Rosenthal P, MacKenzie JD -
Communicable Diseases: A Global Perspective.
The American journal of tropical medicine and hygiene 2016 Rosenthal PJ -
Cryptosporidium and Toxoplasma Parasites Are Inhibited by a Benzoxaborole Targeting Leucyl-tRNA Synthetase.
Antimicrobial agents and chemotherapy 2016 Palencia A, Liu RJ, Lukarska M, Gut J, Bougdour A, Touquet B, Wang ED, Li X, Alley MR, Freund YR, Rosenthal PJ, Hakimi MA, Cusack S -
Intermittent Preventive Treatment with Dihydroartemisinin-Piperaquine in Ugandan Schoolchildren Selects for Plasmodium falciparum Transporter Polymorphisms That Modify Drug Sensitivity.
Antimicrobial agents and chemotherapy 2016 Nankabirwa JI, Conrad MD, Legac J, Tukwasibwe S, Tumwebaze P, Wandera B, Brooker SJ, Staedke SG, Kamya MR, Nsobya SL, Dorsey G, Rosenthal PJ -
4-Aminoquinoline-ferrocenyl-chalcone conjugates: Synthesis and anti-plasmodial evaluation.
European journal of medicinal chemistry 2016 Singh A, Gut J, Rosenthal PJ, Kumar V -
Characterizing microscopic and submicroscopic malaria parasitaemia at three sites with varied transmission intensity in Uganda.
Malaria journal 2016 Rek J, Katrak S, Obasi H, Nayebare P, Katureebe A, Kakande E, Arinaitwe E, Nankabirwa JI, Jagannathan P, Drakeley C, Staedke SG, Smith DL, Bousema T, Kamya M, Rosenthal PJ, Dorsey G, Greenhouse B -
In Children With Nonalcoholic Fatty Liver Disease, Cysteamine Bitartrate Delayed Release Improves Liver Enzymes but Does Not Reduce Disease Activity Scores.
Gastroenterology 2016 Schwimmer JB, Lavine JE, Wilson LA, Neuschwander-Tetri BA, Xanthakos SA, Kohli R, Barlow SE, Vos MB, Karpen SJ, Molleston JP, Whitington PF, Rosenthal P, Jain AK, Murray KF, Brunt EM, Kleiner DE, Van … -
Probing the Azaaurone Scaffold against the Hepatic and Erythrocytic Stages of Malaria Parasites.
ChemMedChem 2016 Carrasco MP, Machado M, Gonçalves L, Sharma M, Gut J, Lukens AK, Wirth DF, André V, Duarte MT, Guedes RC, Dos Santos DJ, Rosenthal PJ, Mazitschek R, Prudêncio M, Moreira R -
Chronic Hepatitis C Infection in Children.
Advances in pediatrics 2016 Pham YH, Rosenthal P -
Five-year histological and serological follow-up of operationally tolerant pediatric liver transplant recipients enrolled in WISP-R.
Hepatology (Baltimore, Md.) 2016 Feng S, Demetris AJ, Spain KM, Kanaparthi S, Burrell BE, Ekong UD, Alonso EM, Rosenthal P, Turka LA, Ikle D, Tchao NK -
Antimalarial Benzoxaboroles Target Plasmodium falciparum Leucyl-tRNA Synthetase.
Antimicrobial agents and chemotherapy 2016 Sonoiki E, Palencia A, Guo D, Ahyong V, Dong C, Li X, Hernandez VS, Zhang YK, Choi W, Gut J, Legac J, Cooper R, Alley MR, Freund YR, DeRisi J, Cusack S, Rosenthal PJ -
Azithromycin for Malaria?
The American journal of tropical medicine and hygiene 2016 Rosenthal PJ -
Novel squaramides with in vitro liver stage antiplasmodial activity.
Bioorganic & medicinal chemistry 2016 Ribeiro CJ, Espadinha M, Machado M, Gut J, Gonçalves LM, Rosenthal PJ, Prudêncio M, Moreira R, Santos MM -
Durability of Response in Children Treated With Pegylated Interferon alfa [corrected] 2a ± Ribavirin for Chronic Hepatitis C.
Journal of pediatric gastroenterology and nutrition 2016 Schwarz KB, Molleston JP, Jonas MM, Wen J, Murray KF, Rosenthal P, Gonzalez-Peralta RP, Lobritto SJ, Mogul D, Pavlovic V, Warne C, Wat C, Thompson B -
Estimating malaria parasite prevalence from community surveys in Uganda: a comparison of microscopy, rapid diagnostic tests and polymerase chain reaction.
Malaria journal 2015 Nankabirwa JI, Yeka A, Arinaitwe E, Kigozi R, Drakeley C, Kamya MR, Greenhouse B, Rosenthal PJ, Dorsey G, Staedke SG -
Total Serum Bilirubin within 3 Months of Hepatoportoenterostomy Predicts Short-Term Outcomes in Biliary Atresia.
The Journal of pediatrics 2015 Shneider BL, Magee JC, Karpen SJ, Rand EB, Narkewicz MR, Bass LM, Schwarz K, Whitington PF, Bezerra JA, Kerkar N, Haber B, Rosenthal P, Turmelle YP, Molleston JP, Murray KF, Ng VL, Wang KS, Romero R, … -
Liver capsule: Age-influenced hepatic immune priming determines HBV infection fate: Implications from mouse to man.
Hepatology (Baltimore, Md.) 2015 Publicover J, Jespersen JM, Johnson AJ, Nishimura SL, Goodsell A, Wakil AE, Rosenthal P, Pai E, Avanesyan L, Cooper S, Baron JL -
Artesunate/Amodiaquine Versus Artemether/Lumefantrine for the Treatment of Uncomplicated Malaria in Uganda: A Randomized Trial.
The Journal of infectious diseases 2015 Yeka A, Kigozi R, Conrad MD, Lugemwa M, Okui P, Katureebe C, Belay K, Kapella BK, Chang MA, Kamya MR, Staedke SG, Dorsey G, Rosenthal PJ -
Enantiopure Indolizinoindolones with in vitro Activity against Blood- and Liver-Stage Malaria Parasites.
ChemMedChem 2015 Pereira NA, Monteiro Â, Machado M, Gut J, Molins E, Perry MJ, Dourado J, Moreira R, Rosenthal PJ, Prudêncio M, Santos MM -
Randomized, controlled trial of entecavir versus placebo in children with hepatitis B envelope antigen-positive chronic hepatitis B.
Hepatology (Baltimore, Md.) 2015 Jonas MM, Chang MH, Sokal E, Schwarz KB, Kelly D, Kim KM, Ling SC, Rosenthal P, Oraseanu D, Reynolds L, Thiry A, Ackerman P -
Artefenomel: a promising new antimalarial drug.
The Lancet. Infectious diseases 2015 Rosenthal PJ -
Trioxolane-Mediated Delivery of Mefloquine Limits Brain Exposure in a Mouse Model of Malaria.
ACS medicinal chemistry letters 2015 Lauterwasser EM, Fontaine SD, Li H, Gut J, Katneni K, Charman SA, Rosenthal PJ, Bogyo M, Renslo AR -
Children with Chronic Hepatitis B in the United States and Canada.
The Journal of pediatrics 2015 Schwarz KB, Cloonan YK, Ling SC, Murray KF, Rodriguez-Baez N, Schwarzenberg SJ, Teckman J, Ganova-Raeva L, Rosenthal P, Hepatitis B Research Network -
The RTS,S/AS01 vaccine continues to show modest protection against malaria in African infants and children.
Evidence-based medicine 2015 Rosenthal PJ -
Early life predictive markers of liver disease outcome in an International, Multicentre Cohort of children with Alagille syndrome.
Liver international : official journal of the International Association for the Study of the Liver 2015 Mouzaki M, Bass LM, Sokol RJ, Piccoli DA, Quammie C, Loomes KM, Heubi JE, Hertel PM, Scheenstra R, Furuya K, Kutsch E, Spinner NB, Robbins KN, Venkat V, Rosenthal P, Beyene J, Baker A, Kamath BM -
Antimalarial Drug Resistance: Literature Review and Activities and Findings of the ICEMR Network.
The American journal of tropical medicine and hygiene 2015 Cui L, Mharakurwa S, Ndiaye D, Rathod PK, Rosenthal PJ -
Novel serologic biomarkers provide accurate estimates of recent Plasmodium falciparum exposure for individuals and communities.
Proceedings of the National Academy of Sciences of the United States of America 2015 Helb DA, Tetteh KK, Felgner PL, Skinner J, Hubbard A, Arinaitwe E, Mayanja-Kizza H, Ssewanyana I, Kamya MR, Beeson JG, Tappero J, Smith DL, Crompton PD, Rosenthal PJ, Dorsey G, Drakeley CJ, Greenhouse… -
Baseline Analysis of a Young α-1-Antitrypsin Deficiency Liver Disease Cohort Reveals Frequent Portal Hypertension.
Journal of pediatric gastroenterology and nutrition 2015 Teckman JH, Rosenthal P, Abel R, Bass LM, Michail S, Murray KF, Rudnick DA, Thomas DW, Spino C, Arnon R, Hertel PM, Heubi J, Kamath BM, Karnsakul W, Loomes KM, Magee JC, Molleston JP, Romero R, … -
Benzoxaborole antimalarial agents. Part 4. Discovery of potent 6-(2-(alkoxycarbonyl)pyrazinyl-5-oxy)-1,3-dihydro-1-hydroxy-2,1-benzoxaboroles.
Journal of medicinal chemistry 2015 Zhang YK, Plattner JJ, Easom EE, Jacobs RT, Guo D, Sanders V, Freund YR, Campo B, Rosenthal PJ, Bu W, Gamo FJ, Sanz LM, Ge M, Li L, Ding J, Yang Y -
Bacteremia Among Febrile Ugandan Children Treated with Antimalarials Despite a Negative Malaria Test.
The American journal of tropical medicine and hygiene 2015 Kibuuka A, Byakika-Kibwika P, Achan J, Yeka A, Nalyazi JN, Mpimbaza A, Rosenthal PJ, Kamya MR -
Quality of Life and Its Determinants in a Multicenter Cohort of Children with Alagille Syndrome.
The Journal of pediatrics 2015 Kamath BM, Chen Z, Romero R, Fredericks EM, Alonso EM, Arnon R, Heubi J, Hertel PM, Karpen SJ, Loomes KM, Murray KF, Rosenthal P, Schwarz KB, Subbarao G, Teckman JH, Turmelle YP, Wang KS, Sherker AH, … -
Lack of Artemisinin Resistance in Plasmodium falciparum in Uganda Based on Parasitological and Molecular Assays.
Antimicrobial agents and chemotherapy 2015 Cooper RA, Conrad MD, Watson QD, Huezo SJ, Ninsiima H, Tumwebaze P, Nsobya SL, Rosenthal PJ -
Factors Determining δ-Bilirubin Levels in Infants With Biliary Atresia.
Journal of pediatric gastroenterology and nutrition 2015 Ye W, Rosenthal P, Magee JC, Whitington PF, Childhood Liver Disease Research and Education Network -
Extracts from Annona Muricata L. and Annona Reticulata L. (Annonaceae) Potently and Selectively Inhibit Plasmodium Falciparum.
Medicines (Basel, Switzerland) 2015 Yamthe LRT, Fokou PVT, Mbouna CDJ, Keumoe R, Ndjakou BL, Djouonzo PT, Mfopa AN, Legac J, Tsabang N, Gut J, Rosenthal PJ, Boyom FF -
Randomized Noninferiority Trial of Dihydroartemisinin-Piperaquine Compared with Sulfadoxine-Pyrimethamine plus Amodiaquine for Seasonal Malaria Chemoprevention in Burkina Faso.
Antimicrobial agents and chemotherapy 2015 Zongo I, Milligan P, Compaore YD, Some AF, Greenwood B, Tarning J, Rosenthal PJ, Sutherland C, Nosten F, Ouedraogo JB -
The effect of dosing strategies on the therapeutic efficacy of artesunate-amodiaquine for uncomplicated malaria: a meta-analysis of individual patient data.
BMC medicine 2015 WorldWide Antimalarial Resistance Network (WWARN) AS-AQ Study Group, Adjuik MA, Allan R, Anvikar AR, Ashley EA, Ba MS, Barennes H, Barnes KI, Bassat Q, Baudin E, Björkman A, Bompart F, Bonnet M, … -
Synthesis and in vitro antiplasmodial evaluation of 7-chloroquinoline-chalcone and 7-chloroquinoline-ferrocenylchalcone conjugates.
European journal of medicinal chemistry 2015 Raj R, Saini A, Gut J, Rosenthal PJ, Kumar V -
Targeting the erythrocytic and liver stages of malaria parasites with s-triazine-based hybrids.
ChemMedChem 2015 Rodrigues CA, Frade RF, Albuquerque IS, Perry MJ, Gut J, Machado M, Rosenthal PJ, Prudêncio M, Afonso CA, Moreira R -
Allosteric regulation of the Plasmodium falciparum cysteine protease falcipain-2 by heme.
Archives of biochemistry and biophysics 2015 Marques AF, Gomes PS, Oliveira PL, Rosenthal PJ, Pascutti PG, Lima LM -
Malaria transmission, infection, and disease at three sites with varied transmission intensity in Uganda: implications for malaria control.
The American journal of tropical medicine and hygiene 2015 Kamya MR, Arinaitwe E, Wanzira H, Katureebe A, Barusya C, Kigozi SP, Kilama M, Tatem AJ, Rosenthal PJ, Drakeley C, Lindsay SW, Staedke SG, Smith DL, Greenhouse B, Dorsey G -
Impact of antimalarial treatment and chemoprevention on the drug sensitivity of malaria parasites isolated from ugandan children.
Antimicrobial agents and chemotherapy 2015 Tumwebaze P, Conrad MD, Walakira A, LeClair N, Byaruhanga O, Nakazibwe C, Kozak B, Bloome J, Okiring J, Kakuru A, Bigira V, Kapisi J, Legac J, Gut J, Cooper RA, Kamya MR, Havlir DV, Dorsey G, … -
The Effect of Storage and Extraction Methods on Amplification of Plasmodium falciparum DNA from Dried Blood Spots.
The American journal of tropical medicine and hygiene 2015 Schwartz A, Baidjoe A, Rosenthal PJ, Dorsey G, Bousema T, Greenhouse B -
Is the molecular adsorbent recirculating system the answer for children with acute liver failure?
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2015 Rosenthal P -
N10,N11-di-alkylamine indolo[3,2-b]quinolines as hemozoin inhibitors: design, synthesis and antiplasmodial activity.
Bioorganic & medicinal chemistry 2015 Figueiras M, Coelho L, Wicht KJ, Santos SA, Lavrado J, Gut J, Rosenthal PJ, Nogueira F, Egan TJ, Moreira R, Paulo A -
Perspectives on Ebola.
The American journal of tropical medicine and hygiene 2015 Rosenthal PJ, Bausch DG -
Treatment of bile acid amidation defects with glycocholic acid.
Hepatology (Baltimore, Md.) 2014 Heubi JE, Setchell KD, Jha P, Buckley D, Zhang W, Rosenthal P, Potter C, Horslen S, Suskind D -
Reply to Goyal et al.
The Journal of infectious diseases 2014 Hsiang MS, Greenhouse B, Rosenthal PJ -
Synthesis of gallinamide A analogues as potent falcipain inhibitors and antimalarials.
Journal of medicinal chemistry 2014 Conroy T, Guo JT, Elias N, Cergol KM, Gut J, Legac J, Khatoon L, Liu Y, McGowan S, Rosenthal PJ, Hunt NH, Payne RJ -
Synthesis and structure-activity-relationship studies of thiazolidinediones as antiplasmodial inhibitors of the Plasmodium falciparum cysteine protease falcipain-2.
European journal of medicinal chemistry 2014 Sharma RK, Younis Y, Mugumbate G, Njoroge M, Gut J, Rosenthal PJ, Chibale K -
Total serum bilirubin predicts fat-soluble vitamin deficiency better than serum bile acids in infants with biliary atresia.
Journal of pediatric gastroenterology and nutrition 2014 Venkat VL, Shneider BL, Magee JC, Turmelle Y, Arnon R, Bezerra JA, Hertel PM, Karpen SJ, Kerkar N, Loomes KM, Molleston J, Murray KF, Ng VL, Raghunathan T, Rosenthal P, Schwartz K, Sherker AH, Sokol … -
Efficacy and safety of three regimens for the prevention of malaria in young HIV-exposed Ugandan children: a randomized controlled trial.
AIDS (London, England) 2014 Kamya MR, Kapisi J, Bigira V, Clark TD, Kinara S, Mwangwa F, Muhindo MK, Kakuru A, Aweeka FT, Huang L, Jagannathan P, Achan J, Havlir DV, Rosenthal PJ, Dorsey G -
Drug delivery to the malaria parasite using an arterolane-like scaffold.
ChemMedChem 2014 Fontaine SD, Spangler B, Gut J, Lauterwasser EM, Rosenthal PJ, Renslo AR -
Editorial commentary: the conundrum of Lamivudine and tenofovir disoproxil fumarate for hepatitis B: fetus versus infant.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2014 Rosenthal P -
Delineating definitions and risk factors for metabolic syndrome after pediatric liver transplantation.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2014 Perito ER, Rosenthal P -
Long-term growth outcomes in children treated for chronic hepatitis C.
The Journal of pediatrics 2014 Jonas MM, Schwarz KB, Gonzalez-Peralta R, Lobritto S, Molleston JP, Murray KF, Rosenthal P, Wen J, Wat C, Pavlovic V, Warne C -
Absence of putative artemisinin resistance mutations among Plasmodium falciparum in Sub-Saharan Africa: a molecular epidemiologic study.
The Journal of infectious diseases 2014 Taylor SM, Parobek CM, DeConti DK, Kayentao K, Coulibaly SO, Greenwood BM, Tagbor H, Williams J, Bojang K, Njie F, Desai M, Kariuki S, Gutman J, Mathanga DP, Mårtensson A, Ngasala B, Conrad MD, … -
Polymorphisms in K13 and falcipain-2 associated with artemisinin resistance are not prevalent in Plasmodium falciparum isolated from Ugandan children.
PloS one 2014 Conrad MD, Bigira V, Kapisi J, Muhindo M, Kamya MR, Havlir DV, Dorsey G, Rosenthal PJ -
Efficacy and day 7 plasma piperaquine concentrations in African children treated for uncomplicated malaria with dihydroartemisinin-piperaquine.
PloS one 2014 Zongo I, Somé FA, Somda SA, Parikh S, Rouamba N, Rosenthal PJ, Tarning J, Lindegardh N, Nosten F, Ouédraogo JB -
Protective efficacy and safety of three antimalarial regimens for the prevention of malaria in young Ugandan children: a randomized controlled trial.
PLoS medicine 2014 Bigira V, Kapisi J, Clark TD, Kinara S, Mwangwa F, Muhindo MK, Osterbauer B, Aweeka FT, Huang L, Achan J, Havlir DV, Rosenthal PJ, Kamya MR, Dorsey G -
Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: parasite risk factors that affect treatment outcomes for P. falciparum malaria after artemether-lumefantrine and artesunate-amodiaquine.
The American journal of tropical medicine and hygiene 2014 Venkatesan M, Gadalla NB, Stepniewska K, Dahal P, Nsanzabana C, Moriera C, Price RN, Mårtensson A, Rosenthal PJ, Dorsey G, Sutherland CJ, Guérin P, Davis TME, Ménard D, Adam I, Ademowo G, Arze C, … -
β-amino-alcohol tethered 4-aminoquinoline-isatin conjugates: synthesis and antimalarial evaluation.
European journal of medicinal chemistry 2014 Gut J, Rosenthal PJ, Kumar V -
Discovery of highly selective 7-chloroquinoline-thiohydantoins with potent antimalarial activity.
European journal of medicinal chemistry 2014 Raj R, Mehra V, Gut J, Rosenthal PJ, Wicht KJ, Egan TJ, Hopper M, Wrischnik LA, Land KM, Kumar V -
Medical status of 219 children with biliary atresia surviving long-term with their native livers: results from a North American multicenter consortium.
The Journal of pediatrics 2014 Ng VL, Haber BH, Magee JC, Miethke A, Murray KF, Michail S, Karpen SJ, Kerkar N, Molleston JP, Romero R, Rosenthal P, Schwarz KB, Shneider BL, Turmelle YP, Alonso EM, Sherker AH, Sokol RJ, Childhood … -
Synthetic compounds from an in house library as inhibitors of falcipain-2 from Plasmodium falciparum.
Journal of enzyme inhibition and medicinal chemistry 2014 Bertoldo JB, Chiaradia-Delatorre LD, Mascarello A, Leal PC, Cordeiro MN, Nunes RJ, Sarduy ES, Rosenthal PJ, Terenzi H -
Tetraoxane-pyrimidine nitrile hybrids as dual stage antimalarials.
Journal of medicinal chemistry 2014 Oliveira R, Guedes RC, Meireles P, Albuquerque IS, Gonçalves LM, Pires E, Bronze MR, Gut J, Rosenthal PJ, Prudêncio M, Moreira R, O'Neill PM, Lopes F -
Longitudinal outcomes in a cohort of Ugandan children randomized to artemether-lumefantrine versus dihydroartemisinin-piperaquine for the treatment of malaria.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2014 Wanzira H, Kakuru A, Arinaitwe E, Bigira V, Muhindo MK, Conrad M, Rosenthal PJ, Kamya MR, Tappero JW, Dorsey G -
Use of corticosteroids after hepatoportoenterostomy for bile drainage in infants with biliary atresia: the START randomized clinical trial.
JAMA 2014 Bezerra JA, Spino C, Magee JC, Shneider BL, Rosenthal P, Wang KS, Erlichman J, Haber B, Hertel PM, Karpen SJ, Kerkar N, Loomes KM, Molleston JP, Murray KF, Romero R, Schwarz KB, Shepherd R, Suchy FJ, … -
Temporal changes in prevalence of molecular markers mediating antimalarial drug resistance in a high malaria transmission setting in Uganda.
The American journal of tropical medicine and hygiene 2014 Mbogo GW, Nankoberanyi S, Tukwasibwe S, Baliraine FN, Nsobya SL, Conrad MD, Arinaitwe E, Kamya M, Tappero J, Staedke SG, Dorsey G, Greenhouse B, Rosenthal PJ -
Point of care testing for malaria using LAMP, loop mediated isothermal amplification.
The Journal of infectious diseases 2014 Hsiang MS, Greenhouse B, Rosenthal PJ -
Probing the aurone scaffold against Plasmodium falciparum: design, synthesis and antimalarial activity.
European journal of medicinal chemistry 2014 Carrasco MP, Newton AS, Gonçalves L, Góis A, Machado M, Gut J, Nogueira F, Hänscheid T, Guedes RC, dos Santos DJ, Rosenthal PJ, Moreira R -
Artemisinin-based combination therapies are efficacious and safe for treatment of uncomplicated malaria in HIV-infected Ugandan children.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2014 Kakuru A, Achan J, Muhindo MK, Ikilezi G, Arinaitwe E, Mwangwa F, Ruel T, Clark TD, Charlebois E, Rosenthal PJ, Havlir D, Kamya MR, Tappero JW, Dorsey G -
Another explanation for breast milk jaundice.
The Journal of pediatrics 2014 Rosenthal P -
Bis-alkylamine Indolo[3,2-b]quinolines as hemozoin ligands: implications for antimalarial cytostatic and cytocidal activities.
Journal of medicinal chemistry 2014 Paulo A, Figueiras M, Machado M, Charneira C, Lavrado J, Santos SA, Lopes D, Gut J, Rosenthal PJ, Nogueira F, Moreira R -
Virologic and immunologic outcomes of HIV-infected Ugandan children randomized to lopinavir/ritonavir or nonnucleoside reverse transcriptase inhibitor therapy.
Journal of acquired immune deficiency syndromes (1999) 2014 Ruel TD, Kakuru A, Ikilezi G, Mwangwa F, Dorsey G, Rosenthal PJ, Charlebois E, Havlir D, Kamya M, Achan J -
Selection of drug resistance-mediating Plasmodium falciparum genetic polymorphisms by seasonal malaria chemoprevention in Burkina Faso.
Antimicrobial agents and chemotherapy 2014 Somé AF, Zongo I, Compaoré YD, Sakandé S, Nosten F, Ouédraogo JB, Rosenthal PJ -
Cross-talk between malarial cysteine proteases and falstatin: the BC loop as a hot-spot target.
PloS one 2014 Sundararaj S, Saxena AK, Sharma R, Vashisht K, Sharma S, Anvikar A, Dixit R, Rosenthal PJ, Pandey KC -
Estimation of malaria haplotype and genotype frequencies: a statistical approach to overcome the challenge associated with multiclonal infections.
Malaria journal 2014 Taylor AR, Flegg JA, Nsobya SL, Yeka A, Kamya MR, Rosenthal PJ, Dorsey G, Sibley CH, Guerin PJ, Holmes CC -
7-chloroquinoline-isatin conjugates: antimalarial, antitubercular, and cytotoxic evaluation.
Chemical biology & drug design 2014 Raj R, Biot C, Carrère-Kremer S, Kremer L, Guérardel Y, Gut J, Rosenthal PJ, Forge D, Kumar V -
Validation of the ligase detection reaction fluorescent microsphere assay for the detection of Plasmodium falciparum resistance mediating polymorphisms in Uganda.
Malaria journal 2014 Nankoberanyi S, Mbogo GW, LeClair NP, Conrad MD, Tumwebaze P, Tukwasibwe S, Kamya MR, Tappero J, Nsobya SL, Rosenthal PJ -
Impact of intermittent preventive treatment with dihydroartemisinin-piperaquine on malaria in Ugandan schoolchildren: a randomized, placebo-controlled trial.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2014 Nankabirwa JI, Wandera B, Amuge P, Kiwanuka N, Dorsey G, Rosenthal PJ, Brooker SJ, Staedke SG, Kamya MR -
Impact of mass azithromycin distribution on malaria parasitemia during the low-transmission season in Niger: a cluster-randomized trial.
The American journal of tropical medicine and hygiene 2014 Gaynor BD, Amza A, Kadri B, Nassirou B, Lawan O, Maman L, Stoller NE, Yu SN, Chin SA, West SK, Bailey RL, Rosenthal PJ, Keenan JD, Porco TC, Lietman TM -
Comparative impacts over 5 years of artemisinin-based combination therapies on Plasmodium falciparum polymorphisms that modulate drug sensitivity in Ugandan children.
The Journal of infectious diseases 2014 Conrad MD, LeClair N, Arinaitwe E, Wanzira H, Kakuru A, Bigira V, Muhindo M, Kamya MR, Tappero JW, Greenhouse B, Dorsey G, Rosenthal PJ -
Synthesis, biological evaluation, hydration site thermodynamics, and chemical reactivity analysis of α-keto substituted peptidomimetics for the inhibition of Plasmodium falciparum.
Bioorganic & medicinal chemistry letters 2014 Weldon DJ, Shah F, Chittiboyina AG, Sheri A, Chada RR, Gut J, Rosenthal PJ, Shivakumar D, Sherman W, Desai P, Jung JC, Avery MA -
Differential prevalence of transporter polymorphisms in symptomatic and asymptomatic falciparum malaria infections in Uganda.
The Journal of infectious diseases 2014 Tukwasibwe S, Mugenyi L, Mbogo GW, Nankoberanyi S, Maiteki-Sebuguzi C, Joloba ML, Nsobya SL, Staedke SG, Rosenthal PJ -
1H-1,2,3-Triazole-tethered isatin-7-chloroquinoline and 3-hydroxy-indole-7-chloroquinoline conjugates: synthesis and antimalarial evaluation.
Bioorganic & medicinal chemistry letters 2014 Raj R, Gut J, Rosenthal PJ, Kumar V -
Changes at our journal.
The American journal of tropical medicine and hygiene 2014 Rosenthal PJ -
Determination of the antimalarial drug piperaquine in small volume pediatric plasma samples by LC-MS/MS.
Bioanalysis 2014 Kjellin LL, Dorsey G, Rosenthal PJ, Aweeka F, Huang L -
Novel endoperoxide-based transmission-blocking antimalarials with liver- and blood-schizontocidal activities.
ACS medicinal chemistry letters 2013 Miranda D, Capela R, Albuquerque IS, Meireles P, Paiva I, Nogueira F, Amewu R, Gut J, Rosenthal PJ, Oliveira R, Mota MM, Moreira R, Marti F, Prudêncio M, O'Neill PM, Lopes F -
Pediatric liver transplantation for urea cycle disorders and organic acidemias: United Network for Organ Sharing data for 2002-2012.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2013 Perito ER, Rhee S, Roberts JP, Rosenthal P -
Anomalous vertebral artery injured during anterior cervical discectomy: a case report.
Spine 2013 Rosenthal P, Latchaw RE, Kim KD -
Urea/oxalamide tethered β-lactam-7-chloroquinoline conjugates: synthesis and in vitro antimalarial evaluation.
European journal of medicinal chemistry 2013 Singh P, Raj R, Singh P, Gut J, Rosenthal PJ, Kumar V -
4-Aminoquinoline-β-lactam conjugates: synthesis, antimalarial, and antitubercular evaluation.
Chemical biology & drug design 2013 Raj R, Biot C, Carrère-Kremer S, Kremer L, Guérardel Y, Gut J, Rosenthal PJ, Kumar V -
Novel anti-plasmodial hits identified by virtual screening of the ZINC database.
Journal of computer-aided molecular design 2013 Mugumbate G, Newton AS, Rosenthal PJ, Gut J, Moreira R, Chibale K, Guedes RC -
Synthesis and in vitro and in vivo pharmacological evaluation of new 4-aminoquinoline-based compounds.
ACS medicinal chemistry letters 2013 Tukulula M, Njoroge M, Abay ET, Mugumbate GC, Wiesner L, Taylor D, Gibhard L, Norman J, Swart KJ, Gut J, Rosenthal PJ, Barteau S, Streckfuss J, Kameni-Tcheudji J, Chibale K -
Evaluating progression of liver disease from repeat liver biopsies in children with chronic hepatitis C: a retrospective study.
Hepatology (Baltimore, Md.) 2013 Mohan P, Barton BA, Narkewicz MR, Molleston JP, Gonzalez-Peralta RP, Rosenthal P, Murray KF, Haber B, Schwarz KB, Goodman ZD -
Structural optimization of quinolon-4(1H)-imines as dual-stage antimalarials: toward increased potency and metabolic stability.
Journal of medicinal chemistry 2013 Ressurreição AS, Gonçalves D, Sitoe AR, Albuquerque IS, Gut J, Góis A, Gonçalves LM, Bronze MR, Hanscheid T, Biagini GA, Rosenthal PJ, Prudêncio M, O'Neill P, Mota MM, Lopes F, Moreira R -
Flavones as isosteres of 4(1H)-quinolones: discovery of ligand efficient and dual stage antimalarial lead compounds.
European journal of medicinal chemistry 2013 Rodrigues T, Ressurreição AS, da Cruz FP, Albuquerque IS, Gut J, Carrasco MP, Gonçalves D, Guedes RC, dos Santos DJ, Mota MM, Rosenthal PJ, Moreira R, Prudêncio M, Lopes F -
Extrahepatic anomalies in infants with biliary atresia: results of a large prospective North American multicenter study.
Hepatology (Baltimore, Md.) 2013 Schwarz KB, Haber BH, Rosenthal P, Mack CL, Moore J, Bove K, Bezerra JA, Karpen SJ, Kerkar N, Shneider BL, Turmelle YP, Whitington PF, Molleston JP, Murray KF, Ng VL, Romero R, Wang KS, Sokol RJ, … -
Squaric acid/4-aminoquinoline conjugates: novel potent antiplasmodial agents.
European journal of medicinal chemistry 2013 Ribeiro CJ, Kumar SP, Gut J, Gonçalves LM, Rosenthal PJ, Moreira R, Santos MM -
Biochemical and immunological mechanisms by which sickle cell trait protects against malaria.
Malaria journal 2013 Gong L, Parikh S, Rosenthal PJ, Greenhouse B -
Blocking Plasmodium falciparum development via dual inhibition of hemoglobin degradation and the ubiquitin proteasome system by MG132.
PloS one 2013 Prasad R, Kolla VK, Legac J, Singhal N, Navale R, Rosenthal PJ, Sijwali PS -
The interplay between drug resistance and fitness in malaria parasites.
Molecular microbiology 2013 Rosenthal PJ -
Age-dependent hepatic lymphoid organization directs successful immunity to hepatitis B.
The Journal of clinical investigation 2013 Publicover J, Gaggar A, Nishimura S, Van Horn CM, Goodsell A, Muench MO, Reinhardt RL, van Rooijen N, Wakil AE, Peters M, Cyster JG, Erle DJ, Rosenthal P, Cooper S, Baron JL -
Cervical adjacent segment pathology following fusion: Is it due to fusion?
World journal of orthopedics 2013 Rosenthal P, Kim KD -
Antiplasmodial sesquiterpenes from the seeds of Salacia longipes var. camerunensis.
Phytochemistry 2013 Mba'ning BM, Lenta BN, Noungoué DT, Antheaume C, Fongang YF, Ngouela SA, Boyom FF, Rosenthal PJ, Tsamo E, Sewald N, Laatsch H -
An endoperoxide-based hybrid approach to deliver falcipain inhibitors inside malaria parasites.
ChemMedChem 2013 Oliveira R, Newton AS, Guedes RC, Miranda D, Amewu RK, Srivastava A, Gut J, Rosenthal PJ, O'Neill PM, Ward SA, Lopes F, Moreira R -
Tetrazole-based deoxyamodiaquines: synthesis, ADME/PK profiling and pharmacological evaluation as potential antimalarial agents.
Bioorganic & medicinal chemistry 2013 Tukulula M, Njoroge M, Mugumbate GC, Gut J, Rosenthal PJ, Barteau S, Streckfuss J, Heudi O, Kameni-Tcheudji J, Chibale K -
Biological evaluation of hydroxynaphthoquinones as anti-malarials.
Malaria journal 2013 Schuck DC, Ferreira SB, Cruz LN, da Rocha DR, Moraes MS, Nakabashi M, Rosenthal PJ, Ferreira VF, Garcia CR -
An artesunate-containing antimalarial treatment regimen did not suppress cytomegalovirus viremia.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2013 Gantt S, Huang ML, Magaret A, Bunts L, Selke S, Wald A, Rosenthal PJ, Dorsey G, Casper C -
Fitness Consequences of Plasmodium falciparum pfmdr1 Polymorphisms Inferred from Ex Vivo Culture of Ugandan Parasites.
Antimicrobial agents and chemotherapy 2013 Ochong E, Tumwebaze PK, Byaruhanga O, Greenhouse B, Rosenthal PJ -
Exploring the Molecular Basis of Qo bc1 Complex Inhibitors Activity to Find Novel Antimalarials Hits.
Molecular informatics 2013 Carrasco MP, Gut J, Rodrigues T, Ribeiro MH, Lopes F, Rosenthal PJ, Moreira R, Dos Santos DJ -
Health related quality of life in patients with biliary atresia surviving with their native liver.
The Journal of pediatrics 2013 Sundaram SS, Alonso EM, Haber B, Magee JC, Fredericks E, Kamath B, Kerkar N, Rosenthal P, Shepherd R, Limbers C, Varni JW, Robuck P, Sokol RJ, Childhood Liver Disease Research and Education Network (… -
Optimization of a ligase detection reaction-fluorescent microsphere assay for characterization of resistance-mediating polymorphisms in African samples of Plasmodium falciparum.
Journal of clinical microbiology 2013 LeClair NP, Conrad MD, Baliraine FN, Nsanzabana C, Nsobya SL, Rosenthal PJ -
Quinolin-4(1H)-imines are potent antiplasmodial drugs targeting the liver stage of malaria.
Journal of medicinal chemistry 2013 Rodrigues T, da Cruz FP, Lafuente-Monasterio MJ, Gonçalves D, Ressurreição AS, Sitoe AR, Bronze MR, Gut J, Schneider G, Mota MM, Rosenthal PJ, Prudêncio M, Gamo FJ, Lopes F, Moreira R -
Design, Synthesis, and Antiplasmodial Activity of Hybrid Compounds Based on (2R,3S)-N-Benzoyl-3-phenylisoserine.
ACS medicinal chemistry letters 2013 Njogu PM, Gut J, Rosenthal PJ, Chibale K -
Synthesis, Antiplasmodial Activity, and β-Hematin Inhibition of Hydroxypyridone-Chloroquine Hybrids.
ACS medicinal chemistry letters 2013 Andayi WA, Egan TJ, Gut J, Rosenthal PJ, Chibale K -
In vitro and in vivo antimalarial efficacies of optimized tetracyclines.
Antimicrobial agents and chemotherapy 2013 Draper MP, Bhatia B, Assefa H, Honeyman L, Garrity-Ryan LK, Verma AK, Gut J, Larson K, Donatelli J, Macone A, Klausner K, Leahy RG, Odinecs A, Ohemeng K, Rosenthal PJ, Nelson ML -
Falcipain-2 inhibition by suramin and suramin analogues.
Bioorganic & medicinal chemistry 2013 Marques AF, Esser D, Rosenthal PJ, Kassack MU, Lima LM -
Autoantibodies and autoimmune disease during treatment of children with chronic hepatitis C.
Journal of pediatric gastroenterology and nutrition 2013 Molleston JP, Mellman W, Narkewicz MR, Balistreri WF, Gonzalez-Peralta RP, Jonas MM, Lobritto SJ, Mohan P, Murray KF, Njoku D, Rosenthal P, Barton BA, Talor MV, Cheng I, Schwarz KB, Haber BA, PEDS-C … -
Genetic defects in bile acid conjugation cause fat-soluble vitamin deficiency.
Gastroenterology 2013 Setchell KD, Heubi JE, Shah S, Lavine JE, Suskind D, Al-Edreesi M, Potter C, Russell DW, O'Connell NC, Wolfe B, Jha P, Zhang W, Bove KE, Knisely AS, Hofmann AF, Rosenthal P, Bull LN -
Lack of HLA predominance and HLA shared epitopes in biliary Atresia.
SpringerPlus 2013 Mack CL, Anderson KM, Aubrey MT, Rosenthal P, Sokol RJ, Freed BM -
Azide-alkyne cycloaddition en route to 1H-1,2,3-triazole-tethered 7-chloroquinoline-isatin chimeras: synthesis and antimalarial evaluation.
European journal of medicinal chemistry 2013 Raj R, Singh P, Singh P, Gut J, Rosenthal PJ, Kumar V -
Intravenous N-acetylcysteine in pediatric patients with nonacetaminophen acute liver failure: a placebo-controlled clinical trial.
Hepatology (Baltimore, Md.) 2013 Squires RH, Dhawan A, Alonso E, Narkewicz MR, Shneider BL, Rodriguez-Baez N, Olio DD, Karpen S, Bucuvalas J, Lobritto S, Rand E, Rosenthal P, Horslen S, Ng V, Subbarao G, Kerkar N, Rudnick D, Lopez MJ… -
Substrate specificity studies of the cysteine peptidases falcipain-2 and falcipain-3 from Plasmodium falciparum and demonstration of their kininogenase activity.
Molecular and biochemical parasitology 2013 Cotrin SS, Gouvêa IE, Melo PM, Bagnaresi P, Assis DM, Araújo MS, Juliano MA, Gazarini ML, Rosenthal PJ, Juliano L, Carmona AK -
N-cinnamoylated chloroquine analogues as dual-stage antimalarial leads.
Journal of medicinal chemistry 2013 Pérez BC, Teixeira C, Albuquerque IS, Gut J, Rosenthal PJ, Gomes JR, Prudêncio M, Gomes P -
In vitro efficiency of 9-(N-cinnamoylbutyl)aminoacridines against blood- and liver-stage malaria parasites.
Bioorganic & medicinal chemistry letters 2012 Pérez B, Teixeira C, Gomes AS, Albuquerque IS, Gut J, Rosenthal PJ, Prudêncio M, Gomes P -
Associations between antibodies to a panel of Plasmodium falciparum specific antigens and response to sub-optimal antimalarial therapy in Kampala, Uganda.
PloS one 2012 Keh CE, Jha AR, Nzarubara B, Lanar DE, Dutta S, Theisen M, Rosenthal PJ, Dorsey G, Nixon DF, Greenhouse B -
Another drug in the armamentarium to combat hepatitis B virus in adolescents.
Hepatology (Baltimore, Md.) 2012 Rosenthal P -
Antiretroviral agents and prevention of malaria in HIV-infected Ugandan children.
The New England journal of medicine 2012 Achan J, Kakuru A, Ikilezi G, Ruel T, Clark TD, Nsanzabana C, Charlebois E, Aweeka F, Dorsey G, Rosenthal PJ, Havlir D, Kamya MR -
Compounds from Sorindeia juglandifolia (Anacardiaceae) exhibit potent anti-plasmodial activities in vitro and in vivo.
Malaria journal 2012 Kamkumo RG, Ngoutane AM, Tchokouaha LR, Fokou PV, Madiesse EA, Legac J, Kezetas JJ, Lenta BN, Boyom FF, Dimo T, Mbacham WF, Gut J, Rosenthal PJ -
Portal hypertension in children and young adults with biliary atresia.
Journal of pediatric gastroenterology and nutrition 2012 Shneider BL, Abel B, Haber B, Karpen SJ, Magee JC, Romero R, Schwarz K, Bass LM, Kerkar N, Miethke AG, Rosenthal P, Turmelle Y, Robuck PR, Sokol RJ, Childhood Liver Disease Research and Education … -
1,4-naphthoquinone cations as antiplasmodial agents: hydroxy-, acyloxy-, and alkoxy-substituted analogues.
ACS medicinal chemistry letters 2012 Lu X, Altharawi A, Gut J, Rosenthal PJ, Long TE -
The design, synthesis, in silico ADME profiling, antiplasmodial and antimycobacterial evaluation of new arylamino quinoline derivatives.
European journal of medicinal chemistry 2012 Tukulula M, Little S, Gut J, Rosenthal PJ, Wan B, Franzblau SG, Chibale K -
Posttransplant metabolic syndrome in children and adolescents after liver transplantation: a systematic review.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2012 Rothbaum Perito E, Lau A, Rhee S, Roberts JP, Rosenthal P -
Efficacy of fat-soluble vitamin supplementation in infants with biliary atresia.
Pediatrics 2012 Shneider BL, Magee JC, Bezerra JA, Haber B, Karpen SJ, Raghunathan T, Rosenthal P, Schwarz K, Suchy FJ, Kerkar N, Turmelle Y, Whitington PF, Robuck PR, Sokol RJ, Childhood Liver Disease Research … -
Impact of the donor body mass index on the survival of pediatric liver transplant recipients and post-transplant obesity.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2012 Perito ER, Rhee S, Glidden D, Roberts JP, Rosenthal P -
Pegylated interferon for chronic hepatitis C in children affects growth and body composition: results from the pediatric study of hepatitis C (PEDS-C) trial.
Hepatology (Baltimore, Md.) 2012 Jonas MM, Balistreri W, Gonzalez-Peralta RP, Haber B, Lobritto S, Mohan P, Molleston JP, Murray KF, Narkewicz MR, Rosenthal P, Schwarz KB, Barton BA, Shepherd JA, Mitchell PD, Duggan C -
Cinnamic acid/chloroquinoline conjugates as potent agents against chloroquine-resistant Plasmodium falciparum.
ChemMedChem 2012 Pérez B, Teixeira C, Gut J, Rosenthal PJ, Gomes JR, Gomes P -
Benzoheterocyclic amodiaquine analogues with potent antiplasmodial activity: synthesis and pharmacological evaluation.
Bioorganic & medicinal chemistry letters 2012 Ongarora DS, Gut J, Rosenthal PJ, Masimirembwa CM, Chibale K -
NASPGHAN practice guidelines: Diagnosis and management of hepatitis C infection in infants, children, and adolescents.
Journal of pediatric gastroenterology and nutrition 2012 Mack CL, Gonzalez-Peralta RP, Gupta N, Leung D, Narkewicz MR, Roberts EA, Rosenthal P, Schwarz KB, North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition -
Novel cinnamic acid/4-aminoquinoline conjugates bearing non-proteinogenic amino acids: towards the development of potential dual action antimalarials.
European journal of medicinal chemistry 2012 Pérez BC, Teixeira C, Figueiras M, Gut J, Rosenthal PJ, Gomes JR, Gomes P -
Intracellular proteolysis of kininogen by malaria parasites promotes release of active kinins.
Malaria journal 2012 Bagnaresi P, Barros NM, Assis DM, Melo PM, Fonseca RG, Juliano MA, Pesquero JB, Juliano L, Rosenthal PJ, Carmona AK, Gazarini ML -
When should we perform TIPS in children?
Journal of pediatric gastroenterology and nutrition 2012 Rosenthal P -
Management of portal hypertension in children.
World journal of gastroenterology 2012 Gugig R, Rosenthal P -
Fetal outcomes in pregnancies complicated by intrahepatic cholestasis of pregnancy in a Northern California cohort.
PloS one 2012 Rook M, Vargas J, Caughey A, Bacchetti P, Rosenthal P, Bull L -
Auxiliary liver transplantation for Amanita phalloides poisoning.
Journal of pediatric gastroenterology and nutrition 2012 Rosenthal P -
Computer-aided drug design of falcipain inhibitors: virtual screening, structure-activity relationships, hydration site thermodynamics, and reactivity analysis.
Journal of chemical information and modeling 2012 Shah F, Gut J, Legac J, Shivakumar D, Sherman W, Rosenthal PJ, Avery MA -
Phosphonium lipocations as antiparasitic agents.
Bioorganic & medicinal chemistry letters 2012 Long TE, Lu X, Galizzi M, Docampo R, Gut J, Rosenthal PJ -
How do we best diagnose malaria in Africa?
The American journal of tropical medicine and hygiene 2012 Rosenthal PJ -
Complete immunosuppression withdrawal and subsequent allograft function among pediatric recipients of parental living donor liver transplants.
JAMA 2012 Feng S, Ekong UD, Lobritto SJ, Demetris AJ, Roberts JP, Rosenthal P, Alonso EM, Philogene MC, Ikle D, Poole KM, Bridges ND, Turka LA, Tchao NK -
Correlation of vitamin E, uric acid, and diet composition with histologic features of pediatric NAFLD.
Journal of pediatric gastroenterology and nutrition 2012 Vos MB, Colvin R, Belt P, Molleston JP, Murray KF, Rosenthal P, Schwimmer JB, Tonascia J, Unalp A, Lavine JE, NASH CRN Research Group -
Nonalcoholic fatty liver disease in pediatric patients--a problem that is "enormous" and "growing"!
JPEN. Journal of parenteral and enteral nutrition 2012 Rosenthal P -
The effect of HIV on malaria in the context of the current standard of care for HIV-infected populations in Africa.
Future virology 2012 Kamya MR, Byakika-Kibwika P, Gasasira AF, Havlir D, Rosenthal PJ, Dorsey G, Achan J -
Validation and modification of simplified diagnostic criteria for autoimmune hepatitis in children.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2011 Mileti E, Rosenthal P, Peters MG -
Novel potent metallocenes against liver stage malaria.
Antimicrobial agents and chemotherapy 2011 Matos J, da Cruz FP, Cabrita É, Gut J, Nogueira F, do Rosário VE, Moreira R, Rosenthal PJ, Prudêncio M, Gomes P -
Synthesis, docking and in vitro antimalarial evaluation of bifunctional hybrids derived from β-lactams and 7-chloroquinoline using click chemistry.
Bioorganic & medicinal chemistry letters 2011 Singh P, Singh P, Kumar M, Gut J, Rosenthal PJ, Kumar K, Kumar V, Mahajan MP, Bisetty K -
Overweight and obesity in pediatric liver transplant recipients: prevalence and predictors before and after transplant, United Network for Organ Sharing Data, 1987-2010.
Pediatric transplantation 2011 Perito ER, Glidden D, Roberts JP, Rosenthal P -
Efficacy and safety of artemether-lumefantrine in the treatment of acute, uncomplicated Plasmodium falciparum malaria: a pooled analysis.
The American journal of tropical medicine and hygiene 2011 Makanga M, Bassat Q, Falade CO, Premji ZG, Krudsood S, Hunt P, Walter V, Beck HP, Marrast AC, Cousin M, Rosenthal PJ -
Aza vinyl sulfones: synthesis and evaluation as antiplasmodial agents.
Bioorganic & medicinal chemistry 2011 Glória PM, Gut J, Gonçalves LM, Rosenthal PJ, Moreira R, Santos MM -
Identification of new antimalarial leads by use of virtual screening against cytochrome bc₁.
Bioorganic & medicinal chemistry 2011 Rodrigues T, Moreira R, Gut J, Rosenthal PJ, O Neill PM, Biagini GA, Lopes F, dos Santos DJ, Guedes RC -
In vitro activity of antiretroviral drugs against Plasmodium falciparum.
Antimicrobial agents and chemotherapy 2011 Nsanzabana C, Rosenthal PJ -
Molecular markers of antifolate resistance in Plasmodium falciparum isolates from Luanda, Angola.
Malaria journal 2011 Gama BE, Pereira-Carvalho GA, Lutucuta Kosi FJ, Almeida de Oliveira NK, Fortes F, Rosenthal PJ, do Rosário VE, Daniel-Ribeiro CT, de Fátima Ferreira-da-Cruz M -
Design and evaluation of primaquine-artemisinin hybrids as a multistage antimalarial strategy.
Antimicrobial agents and chemotherapy 2011 Capela R, Cabal GG, Rosenthal PJ, Gut J, Mota MM, Moreira R, Lopes F, Prudêncio M -
In vitro sensitivity of Plasmodium falciparum field isolates to extracts from Cameroonian Annonaceae plants.
Parasitology research 2011 Kemgne EA, Mbacham WF, Boyom FF, Zollo PH, Tsamo E, Rosenthal PJ -
Malaria in Uganda: challenges to control on the long road to elimination. II. The path forward.
Acta tropica 2011 Talisuna A, Adibaku S, Dorsey G, Kamya MR, Rosenthal PJ -
Lessons from sickle cell disease in the treatment and control of malaria.
The New England journal of medicine 2011 Rosenthal PJ -
Artemisinin activity against Plasmodium falciparum requires hemoglobin uptake and digestion.
Proceedings of the National Academy of Sciences of the United States of America 2011 Klonis N, Crespo-Ortiz MP, Bottova I, Abu-Bakar N, Kenny S, Rosenthal PJ, Tilley L -
Development of antitrypanosomal and antiplasmodial nonpeptidic cysteine protease inhibitors based on N-protected-guanidino-furan and -pyrrole building blocks.
ChemMedChem 2011 Langolf S, Machon U, Ehlers M, Sicking W, Schirmeister T, Büchhold C, Gelhaus C, Rosenthal PJ, Schmuck C -
Quinine, an old anti-malarial drug in a modern world: role in the treatment of malaria.
Malaria journal 2011 Achan J, Talisuna AO, Erhart A, Yeka A, Tibenderana JK, Baliraine FN, Rosenthal PJ, D'Alessandro U -
Enone- and chalcone-chloroquinoline hybrid analogues: in silico guided design, synthesis, antiplasmodial activity, in vitro metabolism, and mechanistic studies.
Journal of medicinal chemistry 2011 Guantai EM, Ncokazi K, Egan TJ, Gut J, Rosenthal PJ, Bhampidipati R, Kopinathan A, Smith PJ, Chibale K -
Mining a cathepsin inhibitor library for new antiparasitic drug leads.
PLoS neglected tropical diseases 2011 Ang KK, Ratnam J, Gut J, Legac J, Hansell E, Mackey ZB, Skrzypczynska KM, Debnath A, Engel JC, Rosenthal PJ, McKerrow JH, Arkin MR, Renslo AR -
Morphologic findings in progressive familial intrahepatic cholestasis 2 (PFIC2): correlation with genetic and immunohistochemical studies.
The American journal of surgical pathology 2011 Evason K, Bove KE, Finegold MJ, Knisely AS, Rhee S, Rosenthal P, Miethke AG, Karpen SJ, Ferrell LD, Kim GE -
Peginterferon with or without ribavirin has minimal effect on quality of life, behavioral/emotional, and cognitive outcomes in children.
Hepatology (Baltimore, Md.) 2011 Rodrigue JR, Balistreri W, Haber B, Jonas MM, Mohan P, Molleston JP, Murray KF, Narkewicz MR, Rosenthal P, Smith LJ, Lobritto SJ, Schwarz KB, Robuck PR, Barton B, González-Peralta RP -
Effect of vitamin E or metformin for treatment of nonalcoholic fatty liver disease in children and adolescents: the TONIC randomized controlled trial.
JAMA 2011 Lavine JE, Schwimmer JB, Van Natta ML, Molleston JP, Murray KF, Rosenthal P, Abrams SH, Scheimann AO, Sanyal AJ, Chalasani N, Tonascia J, Ünalp A, Clark JM, Brunt EM, Kleiner DE, Hoofnagle JH, Robuck … -
Identification of novel malarial cysteine protease inhibitors using structure-based virtual screening of a focused cysteine protease inhibitor library.
Journal of chemical information and modeling 2011 Shah F, Mukherjee P, Gut J, Legac J, Rosenthal PJ, Tekwani BL, Avery MA -
Malaria in Uganda: challenges to control on the long road to elimination: I. Epidemiology and current control efforts.
Acta tropica 2011 Yeka A, Gasasira A, Mpimbaza A, Achan J, Nankabirwa J, Nsobya S, Staedke SG, Donnelly MJ, Wabwire-Mangen F, Talisuna A, Dorsey G, Kamya MR, Rosenthal PJ -
Pseudo gallbladder sign in biliary atresia--an imaging pitfall.
Pediatric radiology 2011 Aziz S, Wild Y, Rosenthal P, Goldstein RB -
Novel thiolactone-isatin hybrids as potential antimalarial and antitubercular agents.
Bioorganic & medicinal chemistry letters 2011 Hans RH, Wiid IJ, van Helden PD, Wan B, Franzblau SG, Gut J, Rosenthal PJ, Chibale K -
Management of portal hypertension in children.
Current gastroenterology reports 2011 Mileti E, Rosenthal P -
An image-based assay for high throughput screening of Giardia lamblia.
Journal of microbiological methods 2011 Gut J, Ang KK, Legac J, Arkin MR, Rosenthal PJ, McKerrow JH -
Potent antiplasmodial extracts from Cameroonian Annonaceae.
Journal of ethnopharmacology 2011 Boyom FF, Fokou PV, Yamthe LR, Mfopa AN, Kemgne EM, Mbacham WF, Tsamo E, Zollo PH, Gut J, Rosenthal PJ -
Design, synthesis and evaluation of 3-methylene-substituted indolinones as antimalarials.
European journal of medicinal chemistry 2011 Praveen Kumar S, Gut J, Guedes RC, Rosenthal PJ, Santos MM, Moreira R -
Incorporation of basic side chains into cryptolepine scaffold: structure-antimalarial activity relationships and mechanistic studies.
Journal of medicinal chemistry 2011 Lavrado J, Cabal GG, Prudêncio M, Mota MM, Gut J, Rosenthal PJ, Díaz C, Guedes RC, dos Santos DJ, Bichenkova E, Douglas KT, Moreira R, Paulo A -
New cis-configured aziridine-2-carboxylates as aspartic acid protease inhibitors.
ChemMedChem 2011 Büchold C, Hemberger Y, Heindl C, Welker A, Degel B, Pfeuffer T, Staib P, Schneider S, Rosenthal PJ, Gut J, Morschhäuser J, Bringmann G, Schirmeister T -
Falcipains and other cysteine proteases of malaria parasites.
Advances in experimental medicine and biology 2011 Rosenthal PJ -
FRET peptides reveal differential proteolytic activation in intraerythrocytic stages of the malaria parasites Plasmodium berghei and Plasmodium yoelii.
International journal for parasitology 2010 Cruz LN, Alves E, Leal MT, Juliano MA, Rosenthal PJ, Juliano L, Garcia CR -
Synthesis and structure-activity relationships of novel benzoxaboroles as a new class of antimalarial agents.
Bioorganic & medicinal chemistry letters 2010 Zhang YK, Plattner JJ, Freund YR, Easom EE, Zhou Y, Gut J, Rosenthal PJ, Waterson D, Gamo FJ, Angulo-Barturen I, Ge M, Li Z, Li L, Jian Y, Cui H, Wang H, Yang J -
Brazilian Plasmodium falciparum isolates: investigation of candidate polymorphisms for artemisinin resistance before introduction of artemisinin-based combination therapy.
Malaria journal 2010 Gama BE, de Oliveira NK, de Souza JM, Santos F, de Carvalho LJ, Melo YF, Rosenthal PJ, Daniel-Ribeiro CT, Ferreira-da-Cruz Mde F -
Antiplasmodial volatile extracts from Cleistopholis patens Engler & Diels and Uvariastrum pierreanum Engl. (Engl. & Diels) (Annonaceae) growing in Cameroon.
Parasitology research 2010 Boyom FF, Ngouana V, Kemgne EA, Zollo PH, Menut C, Bessiere JM, Gut J, Rosenthal PJ -
Interpreting conjugated bilirubin levels in newborns.
The Journal of pediatrics 2010 Davis AR, Rosenthal P, Escobar GJ, Newman TB -
Design, synthesis, and development of novel guaianolide-endoperoxides as potential antimalarial agents.
Journal of medicinal chemistry 2010 Sun L, Shah F, Helal MA, Wu Y, Pedduri Y, Chittiboyina AG, Gut J, Rosenthal PJ, Avery MA -
Design, synthesis and in vitro antimalarial evaluation of triazole-linked chalcone and dienone hybrid compounds.
Bioorganic & medicinal chemistry 2010 Guantai EM, Ncokazi K, Egan TJ, Gut J, Rosenthal PJ, Smith PJ, Chibale K -
The combination of ribavirin and peginterferon is superior to peginterferon and placebo for children and adolescents with chronic hepatitis C.
Gastroenterology 2010 Schwarz KB, Gonzalez-Peralta RP, Murray KF, Molleston JP, Haber BA, Jonas MM, Rosenthal P, Mohan P, Balistreri WF, Narkewicz MR, Smith L, Lobritto SJ, Rossi S, Valsamakis A, Goodman Z, Robuck PR, … -
Endoperoxide carbonyl falcipain 2/3 inhibitor hybrids: toward combination chemotherapy of malaria through a single chemical entity.
Journal of medicinal chemistry 2010 Gibbons P, Verissimo E, Araujo NC, Barton V, Nixon GL, Amewu RK, Chadwick J, Stocks PA, Biagini GA, Srivastava A, Rosenthal PJ, Gut J, Guedes RC, Moreira R, Sharma R, Berry N, Cristiano ML, Shone AE, … -
Efficacy, safety, and tolerability of three regimens for prevention of malaria: a randomized, placebo-controlled trial in Ugandan schoolchildren.
PloS one 2010 Nankabirwa J, Cundill B, Clarke S, Kabatereine N, Rosenthal PJ, Dorsey G, Brooker S, Staedke SG -
Biochemical properties of a novel cysteine protease of Plasmodium vivax, vivapain-4.
PLoS neglected tropical diseases 2010 Na BK, Bae YA, Zo YG, Choe Y, Kim SH, Desai PV, Avery MA, Craik CS, Kim TS, Rosenthal PJ, Kong Y -
Antiplasmodial constituents from the fruit pericarp of Pentadesma butyracea.
Planta medica 2010 Lenta BN, Kamdem LM, Ngouela S, Tantangmo F, Devkota KP, Boyom FF, Rosenthal PJ, Tsamo E -
Treatment of children with chronic hepatitis B virus infection in the United States: patient selection and therapeutic options.
Hepatology (Baltimore, Md.) 2010 Jonas MM, Block JM, Haber BA, Karpen SJ, London WT, Murray KF, Narkewicz MR, Rosenthal P, Schwarz KB, McMahon BJ, Hepatitis B Foundation -
Falcipain inhibitors: optimization studies of the 2-pyrimidinecarbonitrile lead series.
Journal of medicinal chemistry 2010 Coterón JM, Catterick D, Castro J, Chaparro MJ, Díaz B, Fernández E, Ferrer S, Gamo FJ, Gordo M, Gut J, de las Heras L, Legac J, Marco M, Miguel J, Muñoz V, Porras E, de la Rosa JC, Ruiz JR, Sandoval … -
Bis-alkylamine quindolone derivatives as new antimalarial leads.
Bioorganic & medicinal chemistry letters 2010 Lavrado J, Gani K, Nobre PA, Santos SA, Figueiredo P, Lopes D, Rosário Vd, Gut J, Rosenthal PJ, Moreira R, Paulo A -
Ophthalmologic complications in children with chronic hepatitis C treated with pegylated interferon.
Journal of pediatric gastroenterology and nutrition 2010 Narkewicz MR, Rosenthal P, Schwarz KB, Drack A, Margolis T, Repka MX, PEDS-C Study Group -
Acute HIV-1 infection is highly prevalent in Ugandan adults with suspected malaria.
AIDS (London, England) 2010 Bebell LM, Pilcher CD, Dorsey G, Havlir D, Kamya MR, Busch MP, Dunn Williams J, Nugent CT, Bentsen C, Rosenthal PJ, Charlebois ED -
Synthesis and in vitro evaluation of gold(I) thiosemicarbazone complexes for antimalarial activity.
Journal of inorganic biochemistry 2010 Khanye SD, Smith GS, Lategan C, Smith PJ, Gut J, Rosenthal PJ, Chibale K -
Effect of trimethoprim-sulphamethoxazole on the risk of malaria in HIV-infected Ugandan children living in an area of widespread antifolate resistance.
Malaria journal 2010 Gasasira AF, Kamya MR, Ochong EO, Vora N, Achan J, Charlebois E, Ruel T, Kateera F, Meya DN, Havlir D, Rosenthal PJ, Dorsey G -
Plasmodium falciparum isolates from Angola show the StctVMNT haplotype in the pfcrt gene.
Malaria journal 2010 Gama BE, Pereira-Carvalho GA, Lutucuta Kosi FJ, Almeida de Oliveira NK, Fortes F, Rosenthal PJ, Daniel-Ribeiro CT, de Fátima Ferreira-da-Cruz M -
Chemical genetics of Plasmodium falciparum.
Nature 2010 Guiguemde WA, Shelat AA, Bouck D, Duffy S, Crowther GJ, Davis PH, Smithson DC, Connelly M, Clark J, Zhu F, Jiménez-Díaz MB, Martinez MS, Wilson EB, Tripathi AK, Gut J, Sharlow ER, Bathurst I, El … -
Functional evaluation of Plasmodium export signals in Plasmodium berghei suggests multiple modes of protein export.
PloS one 2010 Sijwali PS, Rosenthal PJ -
Differences in presentation and progression between severe FIC1 and BSEP deficiencies.
Journal of hepatology 2010 Pawlikowska L, Strautnieks S, Jankowska I, Czubkowski P, Emerick K, Antoniou A, Wanty C, Fischler B, Jacquemin E, Wali S, Blanchard S, Nielsen IM, Bourke B, McQuaid S, Lacaille F, Byrne JA, van Eerde … -
Association between metabolic syndrome and liver histology among children with nonalcoholic Fatty liver disease.
The American journal of gastroenterology 2010 Patton HM, Yates K, Unalp-Arida A, Behling CA, Huang TT, Rosenthal P, Sanyal AJ, Schwimmer JB, Lavine JE -
Selection of known Plasmodium falciparum resistance-mediating polymorphisms by artemether-lumefantrine and amodiaquine-sulfadoxine-pyrimethamine but not dihydroartemisinin-piperaquine in Burkina Faso.
Antimicrobial agents and chemotherapy 2010 Somé AF, Séré YY, Dokomajilar C, Zongo I, Rouamba N, Greenhouse B, Ouédraogo JB, Rosenthal PJ -
Michael acceptor based antiplasmodial and antitrypanosomal cysteine protease inhibitors with unusual amino acids.
Journal of medicinal chemistry 2010 Breuning A, Degel B, Schulz F, Büchold C, Stempka M, Machon U, Heppner S, Gelhaus C, Leippe M, Leyh M, Kisker C, Rath J, Stich A, Gut J, Rosenthal PJ, Schmuck C, Schirmeister T -
Comparison of the antiplasmodial and falcipain-2 inhibitory activity of beta-amino alcohol thiolactone-chalcone and isatin-chalcone hybrids.
Bioorganic & medicinal chemistry letters 2010 Hans RH, Gut J, Rosenthal PJ, Chibale K -
In vitro sensitivities of Plasmodium falciparum to different antimalarial drugs in Uganda.
Antimicrobial agents and chemotherapy 2010 Nsobya SL, Kiggundu M, Nanyunja S, Joloba M, Greenhouse B, Rosenthal PJ -
Synthesis, antimalarial and antitubercular activity of acetylenic chalcones.
Bioorganic & medicinal chemistry letters 2009 Hans RH, Guantai EM, Lategan C, Smith PJ, Wan B, Franzblau SG, Gut J, Rosenthal PJ, Chibale K -
Imidazoquines as antimalarial and antipneumocystis agents.
Journal of medicinal chemistry 2009 Vale N, Prudêncio M, Marques CA, Collins MS, Gut J, Nogueira F, Matos J, Rosenthal PJ, Cushion MT, do Rosário VE, Mota MM, Moreira R, Gomes P -
Antimalarial activity of azadipeptide nitriles.
Bioorganic & medicinal chemistry letters 2009 Löser R, Gut J, Rosenthal PJ, Frizler M, Gütschow M, Andrews KT -
Recommendations for screening, monitoring, and referral of pediatric chronic hepatitis B.
Pediatrics 2009 Haber BA, Block JM, Jonas MM, Karpen SJ, London WT, McMahon BJ, Murray KF, Narkewicz MR, Rosenthal P, Schwarz KB, Hepatitis B Foundation -
Impact of the method of G6PD deficiency assessment on genetic association studies of malaria susceptibility.
PloS one 2009 Johnson MK, Clark TD, Njama-Meya D, Rosenthal PJ, Parikh S -
On-bead screening of a combinatorial fumaric acid derived peptide library yields antiplasmodial cysteine protease inhibitors with unusual peptide sequences.
Journal of medicinal chemistry 2009 Machon U, Büchold C, Stempka M, Schirmeister T, Gelhaus C, Leippe M, Gut J, Rosenthal PJ, Kisker C, Leyh M, Schmuck C -
Treatment of nonalcoholic fatty liver disease in children: TONIC trial design.
Contemporary clinical trials 2009 Lavine JE, Schwimmer JB, Molleston JP, Scheimann AO, Murray KF, Abrams SH, Rosenthal P, Sanyal AJ, Robuck PR, Brunt EM, Unalp A, Tonascia J, Nonalcoholic Steatohepatitis Clinical Research Network … -
Kaposi sarcoma-associated herpesvirus (KSHV) seroprevalence in population-based samples of African children: evidence for at least 2 patterns of KSHV transmission.
The Journal of infectious diseases 2009 Butler LM, Dorsey G, Hladik W, Rosenthal PJ, Brander C, Neilands TB, Mbisa G, Whitby D, Kiepiela P, Mosam A, Mzolo S, Dollard SC, Martin JN -
Effectiveness of quinine versus artemether-lumefantrine for treating uncomplicated falciparum malaria in Ugandan children: randomised trial.
BMJ (Clinical research ed.) 2009 Achan J, Tibenderana JK, Kyabayinze D, Wabwire Mangen F, Kamya MR, Dorsey G, D'Alessandro U, Rosenthal PJ, Talisuna AO -
Vinyl sulfones as antiparasitic agents and a structural basis for drug design.
The Journal of biological chemistry 2009 Kerr ID, Lee JH, Farady CJ, Marion R, Rickert M, Sajid M, Pandey KC, Caffrey CR, Legac J, Hansell E, McKerrow JH, Craik CS, Rosenthal PJ, Brinen LS -
Antiparasitic activities of novel, orally available fumagillin analogs.
Bioorganic & medicinal chemistry letters 2009 Arico-Muendel C, Centrella PA, Contonio BD, Morgan BA, O'Donovan G, Paradise CL, Skinner SR, Sluboski B, Svendsen JL, White KF, Debnath A, Gut J, Wilson N, McKerrow JH, DeRisi JL, Rosenthal PJ, Chiang… -
Predictors of anti-convulsant treatment failure in children presenting with malaria and prolonged seizures in Kampala, Uganda.
Malaria journal 2009 Mpimbaza A, Staedke SG, Ndeezi G, Byarugaba J, Rosenthal PJ -
Regulatory elements within the prodomain of Falcipain-2, a cysteine protease of the malaria parasite Plasmodium falciparum.
PloS one 2009 Pandey KC, Barkan DT, Sali A, Rosenthal PJ -
Design, synthesis and structure-activity relationships of (1H-pyridin-4-ylidene)amines as potential antimalarials.
Bioorganic & medicinal chemistry letters 2009 Rodrigues T, Guedes RC, dos Santos DJ, Carrasco M, Gut J, Rosenthal PJ, Moreira R, Lopes F -
Artemisinin-dipeptidyl vinyl sulfone hybrid molecules: design, synthesis and preliminary SAR for antiplasmodial activity and falcipain-2 inhibition.
Bioorganic & medicinal chemistry letters 2009 Capela R, Oliveira R, Gonçalves LM, Domingos A, Gut J, Rosenthal PJ, Lopes F, Moreira R -
Hemoglobin cleavage site-specificity of the Plasmodium falciparum cysteine proteases falcipain-2 and falcipain-3.
PloS one 2009 Subramanian S, Hardt M, Choe Y, Niles RK, Johansen EB, Legac J, Gut J, Kerr ID, Craik CS, Rosenthal PJ -
Home management of malaria with artemether-lumefantrine compared with standard care in urban Ugandan children: a randomised controlled trial.
Lancet (London, England) 2009 Staedke SG, Mwebaza N, Kamya MR, Clark TD, Dorsey G, Rosenthal PJ, Whitty CJ -
Nontransplant surgical interventions in progressive familial intrahepatic cholestasis.
Journal of pediatric surgery 2009 Davis AR, Rosenthal P, Newman TB -
Antiplasmodial activity of extracts from seven medicinal plants used in malaria treatment in Cameroon.
Journal of ethnopharmacology 2009 Boyom FF, Kemgne EM, Tepongning R, Ngouana V, Mbacham WF, Tsamo E, Zollo PH, Gut J, Rosenthal PJ -
Antimalarial compounds from the stem bark of Vismia laurentii.
Zeitschrift fur Naturforschung. C, Journal of biosciences 2009 Noungoue DT, Chaabi M, Ngouela S, Antheaume C, Boyom FF, Gut J, Rosenthal PJ, Lobstein A, Tsamo E -
Impact of hepatitis C virus infection on children and their caregivers: quality of life, cognitive, and emotional outcomes.
Journal of pediatric gastroenterology and nutrition 2009 Rodrigue JR, Balistreri W, Haber B, Jonas MM, Mohan P, Molleston JP, Murray KF, Narkewicz MR, Rosenthal P, Smith LJ, Schwarz KB, Robuck P, Barton B, González-Peralta RP -
Structures of falcipain-2 and falcipain-3 bound to small molecule inhibitors: implications for substrate specificity.
Journal of medicinal chemistry 2009 Kerr ID, Lee JH, Pandey KC, Harrison A, Sajid M, Rosenthal PJ, Brinen LS -
Caring for adults with pediatric liver disease.
Current gastroenterology reports 2009 Rook M, Rosenthal P -
Pediatric liver retransplantation: outcomes and a prognostic scoring tool.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2009 Davis A, Rosenthal P, Glidden D -
Gingival enlargement in pediatric organ transplant recipients in relation to tacrolimus-based immunosuppressive regimens.
Pediatric dentistry 2009 Shiboski CH, Krishnan S, Besten PD, Golinveaux M, Kawada P, Tornabene A, Rosenthal P, Mathias R -
Oral disease burden and utilization of dental care patterns among pediatric solid organ transplant recipients.
Journal of public health dentistry 2009 Shiboski CH, Kawada P, Golinveaux M, Tornabene A, Krishnan S, Mathias R, Den Besten P, Rosenthal P -
The Distribution and Immune Profile of T Cell Subsets in HIV-Infected Children from Uganda.
AIDS research and human retroviruses 2009 Ssewanyana I, Baker CA, Ruel T, Bousheri S, Kamya M, Dorsey G, Rosenthal PJ, Charlebois E, Havlir D, Cao H -
Synthesis and evaluation of non-peptidic cysteine protease inhibitors of P. falciparum derived from etacrynic acid.
Molecules (Basel, Switzerland) 2008 Dude MA, Kaeppler U, Herb M, Schiller M, Schulz F, Vedder B, Heppner S, Pradel G, Gut J, Rosenthal PJ, Schirmeister T, Leippe M, Gelhaus C -
Complexity of Plasmodium falciparum clinical samples from Uganda during short-term culture.
The Journal of infectious diseases 2008 Nsobya SL, Kiggundu M, Joloba M, Dorsey G, Rosenthal PJ -
Human genetics and malaria: relevance for the design of clinical trials.
The Journal of infectious diseases 2008 Parikh S, Rosenthal PJ -
Synthesis of chlorovinyl sulfones as structural analogs of chalcones and their antiplasmodial activities.
European journal of medicinal chemistry 2008 Dominguez JN, Leon C, Rodrigues J, Gamboa de Dominguez N, Gut J, Rosenthal PJ -
Artemether-lumefantrine versus dihydroartemisinin-piperaquine for treating uncomplicated malaria: a randomized trial to guide policy in Uganda.
PloS one 2008 Yeka A, Dorsey G, Kamya MR, Talisuna A, Lugemwa M, Rwakimari JB, Staedke SG, Rosenthal PJ, Wabwire-Mangen F, Bukirwa H -
Monitoring antimalarial safety and tolerability in clinical trials: a case study from Uganda.
Malaria journal 2008 Staedke SG, Jagannathan P, Yeka A, Bukirwa H, Banek K, Maiteki-Sebuguzi C, Clark TD, Nzarubara B, Njama-Meya D, Mpimbaza A, Rosenthal PJ, Kamya MR, Wabwire-Mangen F, Dorsey G, Talisuna AO -
Safety and tolerability of combination antimalarial therapies for uncomplicated falciparum malaria in Ugandan children.
Malaria journal 2008 Maiteki-Sebuguzi C, Jagannathan P, Yau VM, Clark TD, Njama-Meya D, Nzarubara B, Talisuna AO, Kamya MR, Rosenthal PJ, Dorsey G, Staedke SG -
HIV RNA suppression among HIV-infected Ugandan children with measles.
Journal of acquired immune deficiency syndromes (1999) 2008 Ruel TD, Achan J, Gasasira AF, Charlebois ED, Mehbratu T, Rosenthal PJ, Dorsey G, Kamya MR, Kekitiinwa A, Wong J, Havlir DV -
Imidazolidin-4-one peptidomimetic derivatives of primaquine: synthesis and antimalarial activity.
Bioorganic & medicinal chemistry letters 2008 Vale N, Matos J, Gut J, Nogueira F, do Rosário V, Rosenthal PJ, Moreira R, Gomes P -
A murine model of falciparum-malaria by in vivo selection of competent strains in non-myelodepleted mice engrafted with human erythrocytes.
PloS one 2008 Angulo-Barturen I, Jiménez-Díaz MB, Mulet T, Rullas J, Herreros E, Ferrer S, Jiménez E, Mendoza A, Regadera J, Rosenthal PJ, Bathurst I, Pompliano DL, Gómez de las Heras F, Gargallo-Viola D -
Design and synthesis of novel 2-pyridone peptidomimetic falcipain 2/3 inhibitors.
Bioorganic & medicinal chemistry letters 2008 Verissimo E, Berry N, Gibbons P, Cristiano ML, Rosenthal PJ, Gut J, Ward SA, O'Neill PM -
Discordant patterns of genetic variation at two chloroquine resistance loci in worldwide populations of the malaria parasite Plasmodium falciparum.
Antimicrobial agents and chemotherapy 2008 Mehlotra RK, Mattera G, Bockarie MJ, Maguire JD, Baird JK, Sharma YD, Alifrangis M, Dorsey G, Rosenthal PJ, Fryauff DJ, Kazura JW, Stoneking M, Zimmerman PA -
Hepatitis B in children.
Pediatrics in review 2008 Davis AR, Rosenthal P -
Hepatocarcinoma in viral and metabolic liver disease.
Journal of pediatric gastroenterology and nutrition 2008 Rosenthal P -
Endodesmiadiol, a friedelane triterpenoid, and other antiplasmodial compounds from Endodesmia calophylloides.
Chemical & pharmaceutical bulletin 2008 Ngouamegne ET, Fongang RS, Ngouela S, Boyom FF, Rohmer M, Tsamo E, Gut J, Rosenthal PJ -
Pathology of chronic hepatitis C in children: liver biopsy findings in the Peds-C Trial.
Hepatology (Baltimore, Md.) 2008 Goodman ZD, Makhlouf HR, Liu L, Balistreri W, Gonzalez-Peralta RP, Haber B, Jonas MM, Mohan P, Molleston JP, Murray KF, Narkewicz MR, Rosenthal P, Smith LJ, Robuck PR, Schwarz KB -
Plasmodium food vacuole plasmepsins are activated by falcipains.
The Journal of biological chemistry 2008 Drew ME, Banerjee R, Uffman EW, Gilbertson S, Rosenthal PJ, Goldberg DE -
Rapid diagnostic tests for malaria at sites of varying transmission intensity in Uganda.
The Journal of infectious diseases 2008 Hopkins H, Bebell L, Kambale W, Dokomajilar C, Rosenthal PJ, Dorsey G -
Anti-plasmodial and cholinesterase inhibiting activities of some constituents of Psorospermum glaberrimum.
Chemical & pharmaceutical bulletin 2008 Ndjakou Lenta B, Devkota KP, Ngouela S, Fekam Boyom F, Naz Q, Choudhary MI, Tsamo E, Rosenthal PJ, Sewald N -
Cryptolepine analogues containing basic aminoalkyl side-chains at C-11: synthesis, antiplasmodial activity, and cytotoxicity.
Bioorganic & medicinal chemistry letters 2008 Lavrado J, Paulo A, Gut J, Rosenthal PJ, Moreira R -
HIV-1 infection in patients referred for malaria blood smears at government health clinics in Uganda.
Journal of acquired immune deficiency syndromes (1999) 2007 Bebell LM, Gasasira A, Kiggundu M, Dokomajilar C, Kamya MR, Charlebois ED, Havlir D, Rosenthal PJ, Dorsey G -
Anti-Pneumocystis carinii and antiplasmodial activities of primaquine-derived imidazolidin-4-ones.
Bioorganic & medicinal chemistry letters 2007 Vale N, Collins MS, Gut J, Ferraz R, Rosenthal PJ, Cushion MT, Moreira R, Gomes P -
Pattern of malaria-specific T-cell responses in a cohort of Ugandan children.
Journal of tropical pediatrics 2007 Ssewanyana I, Pietras C, Baker CA, Nghania F, Jones NG, Rosenthal PJ, Dorsey G, Cao H -
Growth failure and outcomes in infants with biliary atresia: a report from the Biliary Atresia Research Consortium.
Hepatology (Baltimore, Md.) 2007 DeRusso PA, Ye W, Shepherd R, Haber BA, Shneider BL, Whitington PF, Schwarz KB, Bezerra JA, Rosenthal P, Karpen S, Squires RH, Magee JC, Robuck PR, Sokol RJ, Biliary Atresia Research Consortium -
Pharmacokinetics of mycophenolate mofetil in stable pediatric liver transplant recipients receiving mycophenolate mofetil and cyclosporine.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2007 Lobritto SJ, Rosenthal P, Bouw R, Leung M, Snell P, Mamelok RD -
Design, synthesis, and antimalarial activity of structural chimeras of thiosemicarbazone and ferroquine analogues.
Bioorganic & medicinal chemistry letters 2007 Biot C, Pradines B, Sergeant MH, Gut J, Rosenthal PJ, Chibale K -
Effects of trimethoprim-sulfamethoxazole and insecticide-treated bednets on malaria among HIV-infected Ugandan children.
AIDS (London, England) 2007 Kamya MR, Gasasira AF, Achan J, Mebrahtu T, Ruel T, Kekitiinwa A, Charlebois ED, Rosenthal PJ, Havlir D, Dorsey G -
World Antimalarial Resistance Network (WARN) III: molecular markers for drug resistant malaria.
Malaria journal 2007 Plowe CV, Roper C, Barnwell JW, Happi CT, Joshi HH, Mbacham W, Meshnick SR, Mugittu K, Naidoo I, Price RN, Shafer RW, Sibley CH, Sutherland CJ, Zimmerman PA, Rosenthal PJ -
Screening of protease inhibitors as antiplasmodial agents. Part I: Aziridines and epoxides.
ChemMedChem 2007 Schulz F, Gelhaus C, Degel B, Vicik R, Heppner S, Breuning A, Leippe M, Gut J, Rosenthal PJ, Schirmeister T -
Immunotherapy for severe aplastic anemia following orthotopic liver transplantation in children.
Pediatric blood & cancer 2007 Sanchez R, Rosenthal P, Goldsby R -
Resistance-mediating Plasmodium falciparum pfcrt and pfmdr1 alleles after treatment with artesunate-amodiaquine in Uganda.
Antimicrobial agents and chemotherapy 2007 Nsobya SL, Dokomajilar C, Joloba M, Dorsey G, Rosenthal PJ -
Artemether-lumefantrine versus dihydroartemisinin-piperaquine for treatment of malaria: a randomized trial.
PLoS clinical trials 2007 Kamya MR, Yeka A, Bukirwa H, Lugemwa M, Rwakimari JB, Staedke SG, Talisuna AO, Greenhouse B, Nosten F, Rosenthal PJ, Wabwire-Mangen F, Dorsey G -
Anti-plasmodial activity of some constituents of the root bark of Harungana madagascariensis LAM. (Hypericaceae).
Chemical & pharmaceutical bulletin 2007 Ndjakou Lenta B, Ngouela S, Fekam Boyom F, Tantangmo F, Feuya Tchouya GR, Tsamo E, Gut J, Rosenthal PJ, Donald Connolly J -
Autoimmune hepatitis in children: diagnosis, pathology and treatment.
Expert review of clinical immunology 2007 Sipe WE, Rosenthal P -
Artemether-lumefantrine versus amodiaquine plus sulfadoxine-pyrimethamine for uncomplicated falciparum malaria in Burkina Faso: a randomised non-inferiority trial.
Lancet (London, England) 2007 Zongo I, Dorsey G, Rouamba N, Tinto H, Dokomajilar C, Guiguemde RT, Rosenthal PJ, Ouedraogo JB -
Synthesis and evaluation of sulfonylurea derivatives as novel antimalarials.
European journal of medicinal chemistry 2007 León C, Rodrigues J, Gamboa de Domínguez N, Charris J, Gut J, Rosenthal PJ, Domínguez JN -
SIR 2006 Annual Meeting Film Panel Case: Budd-Chiari syndrome in a patient with Cogan syndrome.
Journal of vascular and interventional radiology : JVIR 2006 O'Brien MJ, Bloom A, LaBerge JM, Roberts JP, Rosenthal P, Kerlan RK, SIR Foundation -
Synthesis and biological evaluation of phenolic Mannich bases of benzaldehyde and (thio)semicarbazone derivatives against the cysteine protease falcipain-2 and a chloroquine resistant strain of Plasmodium falciparum.
Bioorganic & medicinal chemistry 2006 Chipeleme A, Gut J, Rosenthal PJ, Chibale K -
Effect of cotrimoxazole prophylaxis taken by human immunodeficiency virus (HIV)-infected persons on the selection of sulfadoxine-pyrimethamine-resistant malaria parasites among HIV-uninfected household members.
The American journal of tropical medicine and hygiene 2006 Malamba SS, Mermin J, Reingold A, Lule JR, Downing R, Ransom R, Kigozi A, Hunt BM, Hubbard A, Rosenthal PJ, Dorsey G -
False-positive results of enzyme immunoassays for human immunodeficiency virus in patients with uncomplicated malaria.
Journal of clinical microbiology 2006 Gasasira AF, Dorsey G, Kamya MR, Havlir D, Kiggundu M, Rosenthal PJ, Charlebois ED -
The comprehensive assessment of physical fitness in children following kidney and liver transplantation.
Transplantation 2006 Krasnoff JB, Mathias R, Rosenthal P, Painter PL -
A mathematical model of hepatitis a transmission in the United States indicates value of universal childhood immunization.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2006 Van Effelterre TP, Zink TK, Hoet BJ, Hausdorff WP, Rosenthal P -
Propylthiouracil-associated liver failure presenting as probable autoimmune hepatitis in a child with Graves' disease.
Pediatric transplantation 2006 Sipe WE, Su M, Posselt A, Kim GE, Quiros JA, Rosenthal P -
Artemisinin combination therapies for treatment of uncomplicated malaria in Uganda.
PLoS clinical trials 2006 Bukirwa H, Yeka A, Kamya MR, Talisuna A, Banek K, Bakyaita N, Rwakimari JB, Rosenthal PJ, Wabwire-Mangen F, Dorsey G, Staedke SG -
Application of multicomponent reactions to antimalarial drug discovery. Part 2: New antiplasmodial and antitrypanosomal 4-aminoquinoline gamma- and delta-lactams via a 'catch and release' protocol.
Bioorganic & medicinal chemistry 2006 Musonda CC, Gut J, Rosenthal PJ, Yardley V, Carvalho de Souza RC, Chibale K -
Acute liver failure in children: the first 348 patients in the pediatric acute liver failure study group.
The Journal of pediatrics 2006 Squires RH, Shneider BL, Bucuvalas J, Alonso E, Sokol RJ, Narkewicz MR, Dhawan A, Rosenthal P, Rodriguez-Baez N, Murray KF, Horslen S, Martin MG, Lopez MJ, Soriano H, McGuire BM, Jonas MM, Yazigi N, … -
A multicenter study of the outcome of biliary atresia in the United States, 1997 to 2000.
The Journal of pediatrics 2006 Shneider BL, Brown MB, Haber B, Whitington PF, Schwarz K, Squires R, Bezerra J, Shepherd R, Rosenthal P, Hoofnagle JH, Sokol RJ, Biliary Atresia Research Consortium -
Trends over a decade of pediatric liver transplantation in the United States.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2006 Feng S, Si M, Taranto SE, McBride MA, Mudge C, Stritzel S, Roberts JP, Rosenthal P -
Identification of novel parasitic cysteine protease inhibitors by use of virtual screening. 2. The available chemical directory.
Journal of medicinal chemistry 2006 Desai PV, Patny A, Gut J, Rosenthal PJ, Tekwani B, Srivastava A, Avery M -
Anti-plasmodial and antioxidant activities of constituents of the seed shells of Symphonia globulifera Linn f.
Phytochemistry 2005 Ngouela S, Lenta BN, Noungoue DT, Ngoupayo J, Boyom FF, Tsamo E, Gut J, Rosenthal PJ, Connolly JD -
Underdiagnosis of pediatric obesity and underscreening for fatty liver disease and metabolic syndrome by pediatricians and pediatric subspecialists.
The Journal of pediatrics 2005 Riley MR, Bass NM, Rosenthal P, Merriman RB -
Artemisinin versus nonartemisinin combination therapy for uncomplicated malaria: randomized clinical trials from four sites in Uganda.
PLoS medicine 2005 Yeka A, Banek K, Bakyaita N, Staedke SG, Kamya MR, Talisuna A, Kironde F, Nsobya SL, Kilian A, Slater M, Reingold A, Rosenthal PJ, Wabwire-Mangen F, Dorsey G -
Synthesis and evaluation of new antimalarial phenylurenyl chalcone derivatives.
Journal of medicinal chemistry 2005 Domínguez JN, León C, Rodrigues J, Gamboa de Domínguez N, Gut J, Rosenthal PJ -
Design, synthesis and anti-plasmodial evaluation in vitro of new 4-aminoquinoline isatin derivatives.
Bioorganic & medicinal chemistry 2005 Chiyanzu I, Clarkson C, Smith PJ, Lehman J, Gut J, Rosenthal PJ, Chibale K -
Sulfadoxine-pyrimethamine plus chloroquine or amodiaquine for uncomplicated falciparum malaria: a randomized, multisite trial to guide national policy in Uganda.
The American journal of tropical medicine and hygiene 2005 Bakyaita N, Dorsey G, Yeka A, Banek K, Staedke SG, Kamya MR, Talisuna A, Kironde F, Nsobya S, Kilian A, Reingold A, Rosenthal PJ, Wabwire-Mangen F -
Synthesis and antimalarial activity of sulfonamide chalcone derivatives.
Farmaco (Societa chimica italiana : 1989) 2005 Domínguez JN, León C, Rodrigues J, Gamboa de Domínguez N, Gut J, Rosenthal PJ -
Identification of novel parasitic cysteine protease inhibitors using virtual screening. 1. The ChemBridge database.
Journal of medicinal chemistry 2004 Desai PV, Patny A, Sabnis Y, Tekwani B, Gut J, Rosenthal P, Srivastava A, Avery M -
The influence of portoenterostomy on transplantation for biliary atresia.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2004 Visser BC, Suh I, Hirose S, Rosenthal P, Lee H, Roberts JP, Hirose R -
Evaluation of cysteine proteases of Plasmodium vivax as antimalarial drug targets: sequence analysis and sensitivity to cysteine protease inhibitors.
Parasitology research 2004 Na BK, Kim TS, Rosenthal PJ, Lee JK, Kong Y -
Antiplasmodial chalcones inhibit sorbitol-induced hemolysis of Plasmodium falciparum-infected erythrocytes.
Antimicrobial agents and chemotherapy 2004 Go ML, Liu M, Wilairat P, Rosenthal PJ, Saliba KJ, Kirk K -
Application of multi-component reactions to antimalarial drug discovery. Part 1: Parallel synthesis and antiplasmodial activity of new 4-aminoquinoline Ugi adducts.
Bioorganic & medicinal chemistry letters 2004 Musonda CC, Taylor D, Lehman J, Gut J, Rosenthal PJ, Chibale K -
Maternal microchimerism in the livers of patients with biliary atresia.
BMC gastroenterology 2004 Suskind DL, Rosenthal P, Heyman MB, Kong D, Magrane G, Baxter-Lowe LA, Muench MO -
Antimalarial drug discovery: efficacy models for compound screening.
Nature reviews. Drug discovery 2004 Fidock DA, Rosenthal PJ, Croft SL, Brun R, Nwaka S -
Hepatic failure and liver transplant: Working Group report of the second World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition.
Journal of pediatric gastroenterology and nutrition 2004 Baker A, Alonso ME, Aw MM, Ciocca M, Porta G, Rosenthal P, European Society for Paediatric Gastroenterology, Hepatology and Nutrition -
Molecular evaluation of the natural history of asymptomatic parasitemia in Ugandan children.
The Journal of infectious diseases 2004 Nsobya SL, Parikh S, Kironde F, Lubega G, Kamya MR, Rosenthal PJ, Dorsey G -
Hepatitis A vaccine.
The New England journal of medicine 2004 Rosenthal P -
Prospective, randomized, multicenter, controlled trial of a bioartificial liver in treating acute liver failure.
Annals of surgery 2004 Demetriou AA, Brown RS, Busuttil RW, Fair J, McGuire BM, Rosenthal P, Am Esch JS, Lerut J, Nyberg SL, Salizzoni M, Fagan EA, de Hemptinne B, Broelsch CE, Muraca M, Salmeron JM, Rabkin JM, Metselaar HJ… -
Cost effectiveness of hepatitis A/B versus hepatitis B vaccination for US prison inmates.
Vaccine 2004 Jacobs RJ, Rosenthal P, Meyerhoff AS -
Chronic viral hepatitis.
Adolescent medicine clinics 2004 Suskind DL, Rosenthal P -
5HT1A serotonin receptor agonists inhibit Plasmodium falciparum by blocking a membrane channel.
Antimicrobial agents and chemotherapy 2003 Locher CP, Ruben PC, Gut J, Rosenthal PJ -
Composition and anti-plasmodial activities of essential oils from some Cameroonian medicinal plants.
Phytochemistry 2003 Boyom FF, Ngouana V, Zollo PH, Menut C, Bessiere JM, Gut J, Rosenthal PJ -
Synthesis and evaluation of isatins and thiosemicarbazone derivatives against cruzain, falcipain-2 and rhodesain.
Bioorganic & medicinal chemistry letters 2003 Chiyanzu I, Hansell E, Gut J, Rosenthal PJ, McKerrow JH, Chibale K -
The seroprevalence of Helicobacter pylori in a referral population of children in the United States.
The American journal of gastroenterology 2003 Chong SK, Lou Q, Zollinger TW, Rabinowitz S, Jibaly R, Tolia V, Elitsur Y, Gold BD, Rosenberg A, Johnson A, Elkayam O, Rosenthal P, Gilger M, Li BU, Peacock JS -
Recent studies of adefovir dipivoxil for hepatitis B.
Journal of pediatric gastroenterology and nutrition 2003 Rosenthal P -
Validation of a simplified method for using molecular markers to predict sulfadoxine-pyrimethamine treatment failure in African children with falciparum malaria.
The American journal of tropical medicine and hygiene 2003 Kyabayinze D, Cattamanchi A, Kamya MR, Rosenthal PJ, Dorsey G -
Comparison of drainage techniques for biliary atresia.
Journal of pediatric surgery 2003 Tsao K, Rosenthal P, Dhawan K, Danzer E, Sydorak R, Hirose S, Farmer DL, Albanese CT, Harrison MR, Lee H -
Brain MR imaging in neonatal hyperammonemic encephalopathy resulting from proximal urea cycle disorders.
AJNR. American journal of neuroradiology 2003 Takanashi J, Barkovich AJ, Cheng SF, Weisiger K, Zlatunich CO, Mudge C, Rosenthal P, Tuchman M, Packman S -
Structure-based approach to falcipain-2 inhibitors: synthesis and biological evaluation of 1,6,7-trisubstituted dihydroisoquinolines and isoquinolines.
Bioorganic & medicinal chemistry 2003 Batra S, Sabnis YA, Rosenthal PJ, Avery MA -
Probing the structure of falcipain-3, a cysteine protease from Plasmodium falciparum: comparative protein modeling and docking studies.
Protein science : a publication of the Protein Society 2003 Sabnis YA, Desai PV, Rosenthal PJ, Avery MA -
Cost-effectiveness of hepatitis A vaccination in children, adolescents, and adults.
Hepatology (Baltimore, Md.) 2003 Rosenthal P -
Hepatitis A: a preventable threat.
Journal of pediatric gastroenterology and nutrition 2002 Rosenthal P -
Allograft rejection in pediatric liver transplantation: Comparison between cadaveric and living related donors.
Pediatric transplantation 2002 Toyoki Y, Renz JF, Mudge C, Ascher NL, Roberts JP, Rosenthal P -
Donor health assessment after living-donor liver transplantation.
Annals of surgery 2002 Diaz GC, Renz JF, Mudge C, Roberts JP, Ascher NL, Emond JC, Rosenthal P -
Synthesis and evaluation of new antimalarial analogues of quinoline alkaloids derived from Cinchona ledgeriana Moens ex Trimen.
Bioorganic & medicinal chemistry letters 2002 Park BS, Kim DY, Rosenthal PJ, Huh SC, Lee BJ, Park E-, Kim SM, Kim JE, Kim MH, Huh TL, Choi YJ, Suh KH, Choi WS, Lee SE -
CT and MRI of hepatic pseudotumor in long-standing biliary atresia.
Journal of computer assisted tomography 2002 Wang ZJ, Coakley FV, Ferrell LD, Rosenthal P -
Mushroom poisoning and auxiliary partial orthotopic liver transplantation.
The American journal of gastroenterology 2002 Rosenthal P -
Homology modeling of falcipain-2: validation, de novo ligand design and synthesis of novel inhibitors.
Journal of biomolecular structure & dynamics 2002 Sabnis Y, Rosenthal PJ, Desai P, Avery MA -
Research agenda for pediatric gastroenterology, hepatology and nutrition: transplantation. Report of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition for the Children's Digestive Health and Nutrition Foundation.
Journal of pediatric gastroenterology and nutrition 2002 McDiarmid SV, Bucuvalas JC, Cox KL, Freese DK, Rosenthal P, Vanderhoof JA -
Medical therapy of brain edema in fulminant hepatic failure? Are we there yet?
Journal of pediatric gastroenterology and nutrition 2001 Gugig R, Rosenthal P -
Is interferon therapy in pediatric chronic hepatitis B infection warranted?
Journal of pediatric gastroenterology and nutrition 2000 Huang J, Rosenthal P -
The time is right for the use of liver dialysis devices in patients with hepatorenal syndrome.
Journal of pediatric gastroenterology and nutrition 2000 Rosenthal P -
Current status of pediatric liver transplantation.
Clinics in liver disease 2000 Abramson O, Rosenthal P -
Digestive disease week 2000. American Association for the Study of Liver Diseases.
IDrugs : the investigational drugs journal 2000 Rosenthal P -
Is our approach to treating chronic hepatitis C all wrong?
Journal of pediatric gastroenterology and nutrition 2000 Rosenthal P -
Is it time for separate pediatric hepatology and liver transplant training programs and special certification or qualification?
Journal of pediatric gastroenterology and nutrition 2000 Rosenthal P -
Is there a future for liver-assist devices?
Current gastroenterology reports 2000 Rosenthal P -
Variable morbidity in alagille syndrome: a review of 43 cases.
Journal of pediatric gastroenterology and nutrition 1999 Quiros-Tejeira RE, Ament ME, Heyman MB, Martin MG, Rosenthal P, Hall TR, McDiarmid SV, Vargas JH -
GB virus C (GBV-C/HGV) and E2 antibodies in children preliver and postliver transplant.
Pediatric research 1999 Elkayam O, Hassoba HM, Ferrell LD, Garcia-Kennedy R, Gish RG, Wright TL, Laffler T, Traylor D, Hunt G, Rosenthal P -
Living related donor transplantation: the future.
Journal of pediatric gastroenterology and nutrition 1999 Lightdale JR, Rosenthal P -
Mycophenolate mofetil, microemulsion cyclosporine, and prednisone as primary immunosuppression for pediatric liver transplant recipients.
Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 1999 Renz JF, Lightdale J, Mudge C, Bacchetti P, Watson J, Ascher NL, Emond JC, Rosenthal P, Roberts JP -
Severe congenital anomalies requiring transplantation in children with Kabuki syndrome.
American journal of medical genetics 1998 Ewart-Toland A, Enns GM, Cox VA, Mohan GC, Rosenthal P, Golabi M -
The role of pediatricians in the care of children with liver transplants.
Archives of pediatrics & adolescent medicine 1998 Lightdale JR, Mudge CL, Ascher NL, Rosenthal P -
Hepatitis A vaccine: current indications.
Journal of pediatric gastroenterology and nutrition 1998 Rosenthal P -
Transjugular intrahepatic portosystemic shunts (TIPS) in children.
The Journal of pediatrics 1997 Heyman MB, LaBerge JM, Somberg KA, Rosenthal P, Mudge C, Ring EJ, Snyder JD -
Pathological changes in yearly protocol liver biopsy specimens from healthy pediatric liver recipients.
Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 1997 Rosenthal P, Emond JC, Heyman MB, Snyder J, Roberts J, Ascher N, Ferrell L -
Auxiliary liver transplant in fulminant failure.
Pediatrics 1997 Rosenthal P, Roberts JP, Ascher NL, Emond JC -
Chronic hepatitis C viral infection in childhood: to treat or not to treat with interferon--that is the question.
Journal of pediatric gastroenterology and nutrition 1997 Rosenthal P -
Assessing liver function and hyperbilirubinemia in the newborn. National Academy of Clinical Biochemistry.
Clinical chemistry 1997 Rosenthal P -
Errors in neonatal bilirubin measurement.
Clinical chemistry 1996 Rosenthal P -
Living-related liver transplants for adults? The time has come!
Journal of pediatric gastroenterology and nutrition 1996 Rosenthal P -
Failure patterns of cryopreserved vein grafts in liver transplantation.
Transplantation 1996 Kuang AA, Renz JF, Ferrell LD, Ring EJ, Rosenthal P, Lim RC, Roberts JP, Ascher NL, Emond JC -
Bile ductule formation in fetal, neonatal, and infant livers compared with extrahepatic biliary atresia.
Hepatology (Baltimore, Md.) 1996 Cocjin J, Rosenthal P, Buslon V, Luk L, Barajas L, Geller SA, Ruebner B, French S -
Current therapy for Crigler-Najjar syndrome type 1: report of a world registry.
Hepatology (Baltimore, Md.) 1996 van der Veere CN, Sinaasappel M, McDonagh AF, Rosenthal P, Labrune P, Odièvre M, Fevery J, Otte JB, McClean P, Bürk G, Masakowski V, Sperl W, Mowat AP, Vergani GM, Heller K, Wilson JP, Shepherd R, … -
Is having alpha-1-antitrypsin deficiency necessarily bad for your liver?
The American journal of gastroenterology 1996 Rosenthal P -
Failure of liver transplantation to diminish cardiac deposits of amylopectin and leukocyte inclusions in type IV glycogen storage disease.
Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 1995 Rosenthal P, Podesta L, Grier R, Said JW, Sher L, Cocjin J, Watanabe F, Vasiliauskas E, van de Velde R, Makowka L -
The association of reovirus 3 and biliary atresia: finally resolved?
The American journal of gastroenterology 1995 Rosenthal P -
D-lactic acidosis in patients with short bowel syndrome.
Clinical chemistry 1995 Rosenthal P -
Bilirubin and risk of coronary artery disease.
Clinical chemistry 1994 Rosenthal P -
Neonatal Dubin-Johnson syndrome.
Journal of pediatric gastroenterology and nutrition 1994 Rosenthal P -
Liver transplantation in children.
The American journal of gastroenterology 1994 Rosenthal P, Podesta L, Sher L, Makowka L -
Medical therapies for pediatric gastrointestinal disease. Subcommittee on Therapeutics of the Patient Care Committee North American Society for Pediatric Gastroenterology and Nutrition.
Journal of pediatric gastroenterology and nutrition 1994 Treem WR, Berquist W, Leichtner A, McClung HJ, Rosenthal P, Shulman RJ, Balistreri WF -
Pediatric liver transplantation.
Seminars in pediatric surgery 1993 Podesta L, Rosenthal P, Sher L, Makowka L -
Hepatic pseudomass on ultrasound in children with fatty infiltration of the liver.
Journal of pediatric gastroenterology and nutrition 1993 Sarti DA, Fleisher DR, Rosenthal P -
Automated total and neonatal bilirubin values in newborns: is a distinction clinically relevant?
Clinical chemistry 1992 Langbaum ME, Farber SJ, Rosenthal P -
Direct bilirubin measurements in term newborns--a waste of time and money?
Journal of pediatric gastroenterology and nutrition 1992 Rosenthal P -
Successful late Kasai portoenterostomy.
Journal of pediatric gastroenterology and nutrition 1992 Bielamowicz A, Weitzman JJ, Alshak NS, Rosenthal P -
Evaluation of neonatal cholestasis.
Journal of pediatric gastroenterology and nutrition 1990 Rosenthal P -
Immunogenicity of Haemophilus influenzae type B vaccines in children with hepatoportoenterostomies.
Journal of pediatric gastroenterology and nutrition 1990 Rosenthal P, Wong V, Ross LA, Kim KS -
Total and direct-reacting bilirubin values by automated methods compared with liquid chromatography and with manual methods for determining delta bilirubin.
Clinical chemistry 1990 Rosenthal P, Keefe MT, Henton D, Cheng M, Lee CR, Hall RL, Newton MK -
Aminotransferase as a prognostic index in infants with liver disease.
Clinical chemistry 1990 Rosenthal P, Haight M -
Atropine therapy and paralytic ileus in an infant.
Journal of pediatric gastroenterology and nutrition 1989 Marshall WF, Rosenthal P, Merritt RJ -
Diagnosis of giardiasis.
Journal of pediatric gastroenterology and nutrition 1989 Rosenthal P -
Hepatobiliary scintigraphy and the string test in the evaluation of neonatal cholestasis.
Journal of pediatric gastroenterology and nutrition 1989 Rosenthal P, Miller JH, Sinatra FR -
The BUN/creatinine ratio in localizing gastrointestinal bleeding in pediatric patients.
Journal of pediatric gastroenterology and nutrition 1988 Felber S, Rosenthal P, Henton D -
Orthotopic liver transplantation for type I Crigler-Najjar syndrome.
Hepatology (Baltimore, Md.) 1986 Kaufman SS, Wood RP, Shaw BW, Markin RS, Rosenthal P, Gridelli B, Vanderhoof JA -
Long-term external catheter biliary drainage for recurrent cholangitis after hepatoportoenterostomy.
Journal of pediatric gastroenterology and nutrition 1986 Gleghorn EE, Rosenthal P, Vachon L, Diament M -
Long-term monitoring of D-lactic acidosis in a child.
Journal of pediatric gastroenterology and nutrition 1985 Rosenthal P, Pesce M -
Collection of duodenal bile in infants and children by the string test.
Journal of pediatric gastroenterology and nutrition 1985 Rosenthal P -
Sex- and age-related differences in bilirubin concentrations in serum.
Clinical chemistry 1984 Rosenthal P, Pincus M, Fink D -
Liquid-chromatographic determination of bilirubin and its conjugates in rat serum and human amniotic fluid.
Clinical chemistry 1981 Rosenthal P, Blanckaert N, Kabra PM, Thaler MM