Philip Pauerstein, MD, PhD
Adjunct Instructor
Pediatrics
School of Medicine

Education & Training

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• Fellowship Pediatric Hematology, Oncology, and BMT University of California, San Francisco 07/2024
• Residency Pediatrics University of California, San Francisco 06/2020
• MD, PhD Stanford University 06/2017
• BA Rice University 05/2008

Publications (9)

Top publication keywords:
Gene Expression Regulation, DevelopmentalNeuropilin-2Regulatory Factor X Transcription FactorsNerve Tissue ProteinsDiseasePancreasStaining and LabelingChemotactic FactorsInsulin-Secreting CellsCell EngineeringBasic Helix-Loop-Helix Transcription FactorsIslets of LangerhansSemaphorin-3AOrganogenesisGenetic Techniques

• Engineering synthetic suppressor T cells that execute locally targeted immunoprotective programs.
  Science (New York, N.Y.) 2024 Reddy NR, Maachi H, Xiao Y, Simic MS, Yu W, Tonai Y, Cabanillas DA, Serrano-Wu E, Pauerstein PT, Tamaki W, Allen GM, Parent AV, Hebrok M, Lim WA
• Single-cell transcriptome and accessible chromatin dynamics during endocrine pancreas development.
  Proceedings of the National Academy of Sciences of the United States of America 2022 Duvall E, Benitez CM, Tellez K, Enge M, Pauerstein PT, Li L, Baek S, Quake SR, Smith JP, Sheffield NC, Kim SK, Arda HE
• A radial axis defined by semaphorin-to-neuropilin signaling controls pancreatic islet morphogenesis.
  Development (Cambridge, England) 2017 Pauerstein PT, Tellez K, Willmarth KB, Park KM, Hsueh B, Efsun Arda H, Gu X, Aghajanian H, Deisseroth K, Epstein JA, Kim SK
• Pathways to clinical CLARITY: volumetric analysis of irregular, soft, and heterogeneous tissues in development and disease.
  Scientific reports 2017 Hsueh B, Burns VM, Pauerstein P, Holzem K, Ye L, Engberg K, Wang AC, Gu X, Chakravarthy H, Arda HE, Charville G, Vogel H, Efimov IR, Kim S, Deisseroth K
• Research Resource: Genetic Labeling of Human Islet Alpha Cells.
  Molecular endocrinology (Baltimore, Md.) 2016 Pauerstein PT, Park KM, Peiris HS, Wang J, Kim SK

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• Dissecting Human Gene Functions Regulating Islet Development With Targeted Gene Transduction.
  Diabetes 2015 Pauerstein PT, Sugiyama T, Stanley SE, McLean GW, Wang J, Martín MG, Kim SK
• An integrated cell purification and genomics strategy reveals multiple regulators of pancreas development.
  PLoS genetics 2014 Benitez CM, Qu K, Sugiyama T, Pauerstein PT, Liu Y, Tsai J, Gu X, Ghodasara A, Arda HE, Zhang J, Dekker JD, Tucker HO, Chang HY, Kim SK
• G2 acquisition by transcription-independent mechanism at the zebrafish midblastula transition.
  Developmental biology 2008 Dalle Nogare DE, Pauerstein PT, Lane ME
• A zebrafish LMO4 ortholog limits the size of the forebrain and eyes through negative regulation of six3b and rx3.
  Developmental biology 2007 McCollum CW, Amin SR, Pauerstein P, Lane ME