Peter Hunt, MD
Professor
Medicine
School of Medicine
Peter Hunt is a Professor of Medicine in the Division of Experimental Medicine (DEM) at the University of California San Francisco. He also serves as Associate Chief for Research for the ZSFG-UCSF Department of Medicine, Co-Director of the UCSF-GIVI Center for AIDS Research (for basic and translational science), and as a member of the Leadership Committee of the UCSF AIDS Research Institute.
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He also recently completed terms as Interim Chief of the DEM and Chair of the ACTG Inflammation and End Organ Disease Transformative Science Group. His primary research focus is on the inflammatory consequences of HIV infection. His clinic-based translational research program seeks to understand the determinants of persistent immune activation both in the presence and the absence of antiretroviral therapy, and to assess the impact of immune activation on clinical outcomes. He collaborates extensively with a multi-disciplinary team of investigators to assess the impact of persistent immune activation despite viral suppression on mortality and chronic diseases associated with aging (i.e., cardiovascular disease) and conducts clinical trials of novel immune-based interventions designed to decrease immune activation. Dr. Hunt has also led a translational research program in Mbarara, Uganda, focused on the determinants of immune recovery during suppressive antiretroviral therapy in that setting. He also helped develop a large mucosal immunology program at Zuckerberg San Francisco General Hospital focused on the impact of HIV on gut-associated lymphoid tissue and the determinants of microbial translocation in HIV infection. In 2016, he started a laboratory in the DEM, focused on the immunologic consequences of asymptomatic CMV replication during treated HIV infection as well as the adaptive immune defects that persist in this setting in an effort to develop targets for interventions to reduce morbidity and mortality.
Awards
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- American Society for Clinical Investigation Inductee, ASCI, 2022
- Highly Cited Researcher Award in Cross-Field Category, Clarivate Web of Science, 2022
- Highly Cited Researcher Award in Cross-Field Category, Clarivate Web of Science, 2021
- Highly Cited Researcher Award in Cross-Field Category, Clarivate Web of Science, 2019
- AIDS Research Institute Teaching and Mentoring Award, UCSF, 2015
- Emerging Leader in HIV Research Award, HIVMA, 2010
Education & Training
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- Diversity, Equity, and Inclusion Champion Training University of California 2018
- Infectious Diseases Fellowship Medicine University of California, San Francisco 2005
- General Internal Medicine Fellowship Medicine University of California, San Francisco 2003
- Residency Internal Medicine University of California, San Francisco 2001
- M.D. School of Medicine Yale University 1998
- B.A. Biology Yale University 1994
Grants and Projects
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- Cytomegalovirus (CMV), the gut barrier and immune dysfunction in HIV, NIH, 2021-2026
- Inflammation, Aging, Microbes, Obstructive Lung Disease and Diffusion Abnormalities (I AM OLD-DA) Study, NIH, 2015-2025
- Persistent Functional Immune Defects in Treated HIV Infection, NIH, 2020-2025
- Impact of Treating Asymptomatic CMV Replication on Cardiovascular Risk in Treated HIV Infection, NIH, 2020-2024
- Plasma Proteomic and Metabolomic Predictors of Vascular Disease in Treated HIV, NIH, 2021-2022
- Immunologic and Fat-Associated Predictors of Insulin Resistance in Treated HIV, NIH, 2017-2022
- Timing of ART and homeostasis of the persistent HIV reservoir in the adult, NIH, 2015-2021
- Determinants of Functional Immune Defects in Treated HIV Infection and Aging, NIH, 2014-2020
- The impact of TB co-infection on the reservoir of persistent HIV in vivo, NIH, 2015-2018
- IDO-induced Tryptophan Catabolism and Mortality in Treated HIV-infected Africans, NIH, 2012-2014
- Inflammation, T Cell Senescence, and Mortality in Treated HIV Infection, NIH, 2010-2012
- Innate Immune Response Genetics and T cell Activation in Treated HIV Infection, NIH, 2009-2011
- The Determinants of T Cell Activation in HIV Infection, NIH, 2005-2010
Publications (330)
Top publication keywords:
CD8-Positive T-LymphocytesKynurenineCD4-Positive T-LymphocytesHIV InfectionsCytomegalovirus InfectionsTryptophanAntiretroviral Therapy, Highly ActiveAnti-Retroviral AgentsLymphocyte ActivationViral LoadViremiaHIVAnti-HIV AgentsHIV-1Acquired Immunodeficiency Syndrome
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Abnormal Levels of Some Biomarkers of Immune Activation Despite Very Early Treatment of Human Immunodeficiency Virus.
The Journal of infectious diseases 2021 Schnittman SR, Deitchman AN, Beck-Engeser G, Ahn H, York VA, Hartig H, Hecht FM, Martin JN, Deeks SG, Aweeka FT, Hunt PW -
Antiretroviral Therapy Adherence Interruptions Are Associated With Systemic Inflammation Among Ugandans Who Achieved Viral Suppression.
Journal of acquired immune deficiency syndromes (1999) 2019 Musinguzi N, Castillo-Mancilla J, Morrow M, Byakwaga H, Mawhinney S, Burdo TH, Boum Y, Muzoora C, Bwana BM, Siedner MJ, Martin JN, Hunt PW, Bangsberg DR, Haberer JE -
Kynurenine 3-Monooxygenase Inhibition during Acute Simian Immunodeficiency Virus Infection Lowers PD-1 Expression and Improves Post-Combination Antiretroviral Therapy CD4+ T Cell Counts and Body Weight.
Journal of immunology (Baltimore, Md. : 1950) 2019 Swainson LA, Ahn H, Pajanirassa P, Khetarpal V, Deleage C, Estes JD, Hunt PW, Munoz-Sanjuan I, McCune JM -
Carnitine Is Associated With Atherosclerotic Risk and Myocardial Infarction in HIV -Infected Adults.
Journal of the American Heart Association 2019 Sinha A, Ma Y, Scherzer R, Rahalkar S, Neilan BD, Crane H, Drozd D, Martin J, Deeks SG, Hunt P, Hsue PY -
Increased Systemic Inflammation and Gut Permeability Among Women With Treated HIV Infection in Rural Uganda.
The Journal of infectious diseases 2018 Siedner MJ, Zanni M, Tracy RP, Kwon DS, Tsai AC, Kakuhire B, Hunt PW, Okello S -
The Clinical-Translational Physician-Scientist: Translating Bedside to Bench.
The Journal of infectious diseases 2018 Hunt PW -
Changes in Inflammation but Not in T-Cell Activation Precede Non-AIDS-Defining Events in a Case-Control Study of Patients on Long-term Antiretroviral Therapy.
The Journal of infectious diseases 2018 Angelidou K, Hunt PW, Landay AL, Wilson CC, Rodriguez B, Deeks SG, Bosch RJ, Lederman MM -
Brief Report: Higher ART Adherence Is Associated With Lower Systemic Inflammation in Treatment-Naive Ugandans Who Achieve Virologic Suppression.
Journal of acquired immune deficiency syndromes (1999) 2018 Castillo-Mancilla JR, Morrow M, Boum Y, Byakwaga H, Haberer JE, Martin JN, Bangsberg D, Mawhinney S, Musinguzi N, Huang Y, Tracy RP, Burdo TH, Williams K, Muzzora C, Hunt PW, Siedner MJ -
Early and Delayed Antiretroviral Therapy Results in Comparable Reductions in CD8+ T Cell Exhaustion Marker Expression.
AIDS research and human retroviruses 2017 Rutishauser RL, Hartogensis W, Deguit CD, Krone M, Hoh R, Hecht FM, Pilcher CD, Bacchetti P, Deeks SG, Hunt PW, McCune JM -
Immunologic Pathways That Predict Mortality in HIV-Infected Ugandans Initiating Antiretroviral Therapy.
The Journal of infectious diseases 2017 Lee S, Byakwaga H, Boum Y, Burdo TH, Williams KC, Lederman MM, Huang Y, Tracy RP, Cao H, Haberer JE, Kembabazi A, Bangsberg DR, Martin JN, Hunt PW -
Replication of CMV in the gut of HIV-infected individuals and epithelial barrier dysfunction.
PLoS pathogens 2017 Maidji E, Somsouk M, Rivera JM, Hunt PW, Stoddart CA -
A Randomized Placebo Controlled Trial of Aspirin Effects on Immune Activation in Chronically Human Immunodeficiency Virus-Infected Adults on Virologically Suppressive Antiretroviral Therapy.
Open forum infectious diseases 2017 O'Brien MP, Hunt PW, Kitch DW, Klingman K, Stein JH, Funderburg NT, Berger JS, Tebas P, Clagett B, Moisi D, Utay NS, Aweeka F, Aberg JA -
CD4/CD8 Ratio and KT Ratio Predict Yellow Fever Vaccine Immunogenicity in HIV-Infected Patients.
PLoS neglected tropical diseases 2016 Avelino-Silva VI, Miyaji KT, Hunt PW, Huang Y, Simoes M, Lima SB, Freire MS, Caiaffa-Filho HH, Hong MA, Costa DA, Dias JZ, Cerqueira NB, Nishiya AS, Sabino EC, Sartori AM, Kallas EG -
Immunologic Biomarkers, Morbidity, and Mortality in Treated HIV Infection.
The Journal of infectious diseases 2016 Hunt PW, Lee SA, Siedner MJ -
Limited HIV infection of central memory and stem cell memory CD4+ T cells is associated with lack of progression in viremic individuals.
PLoS pathogens 2014 Klatt NR, Bosinger SE, Peck M, Richert-Spuhler LE, Heigele A, Gile JP, Patel N, Taaffe J, Julg B, Camerini D, Torti C, Martin JN, Deeks SG, Sinclair E, Hecht FM, Lederman MM, Paiardini M, Kirchhoff F,… -
Gut epithelial barrier dysfunction and innate immune activation predict mortality in treated HIV infection.
The Journal of infectious diseases 2014 Hunt PW, Sinclair E, Rodriguez B, Shive C, Clagett B, Funderburg N, Robinson J, Huang Y, Epling L, Martin JN, Deeks SG, Meinert CL, Van Natta ML, Jabs DA, Lederman MM -
Reversal of the Kynurenine pathway of tryptophan catabolism may improve depression in ART-treated HIV-infected Ugandans.
Journal of acquired immune deficiency syndromes (1999) 2014 Martinez P, Tsai AC, Muzoora C, Kembabazi A, Weiser SD, Huang Y, Haberer JE, Martin JN, Bangsberg DR, Hunt PW -
Low proportions of CD28- CD8+ T cells expressing CD57 can be reversed by early ART initiation and predict mortality in treated HIV infection.
The Journal of infectious diseases 2014 Lee SA, Sinclair E, Jain V, Huang Y, Epling L, Van Natta M, Meinert CL, Martin JN, McCune JM, Deeks SG, Lederman MM, Hecht FM, Hunt PW -
The kynurenine pathway of tryptophan catabolism, CD4+ T-cell recovery, and mortality among HIV-infected Ugandans initiating antiretroviral therapy.
The Journal of infectious diseases 2014 Byakwaga H, Boum Y, Huang Y, Muzoora C, Kembabazi A, Weiser SD, Bennett J, Cao H, Haberer JE, Deeks SG, Bangsberg DR, McCune JM, Martin JN, Hunt PW -
Impact of HIV on CD8+ T cell CD57 expression is distinct from that of CMV and aging.
PloS one 2014 Lee SA, Sinclair E, Hatano H, Hsue PY, Epling L, Hecht FM, Bangsberg DR, Martin JN, McCune JM, Deeks SG, Hunt PW -
Dysbiosis of the gut microbiota is associated with HIV disease progression and tryptophan catabolism.
Science translational medicine 2013 Vujkovic-Cvijin I, Dunham RM, Iwai S, Maher MC, Albright RG, Broadhurst MJ, Hernandez RD, Lederman MM, Huang Y, Somsouk M, Deeks SG, Hunt PW, Lynch SV, McCune JM -
The immunologic effects of maraviroc intensification in treated HIV-infected individuals with incomplete CD4+ T-cell recovery: a randomized trial.
Blood 2013 Hunt PW, Shulman NS, Hayes TL, Dahl V, Somsouk M, Funderburg NT, McLaughlin B, Landay AL, Adeyemi O, Gilman LE, Clagett B, Rodriguez B, Martin JN, Schacker TW, Shacklett BL, Palmer S, Lederman MM, … -
HIV and inflammation: mechanisms and consequences.
Current HIV/AIDS reports 2012 Hunt PW -
A role for cytomegalovirus-specific CD4+CX3CR1+ T cells and cytomegalovirus-induced T-cell immunopathology in HIV-associated atherosclerosis.
AIDS (London, England) 2012 Sacre K, Hunt PW, Hsue PY, Maidji E, Martin JN, Deeks SG, Autran B, McCune JM -
Valganciclovir reduces T cell activation in HIV-infected individuals with incomplete CD4+ T cell recovery on antiretroviral therapy.
The Journal of infectious diseases 2011 Hunt PW, Martin JN, Sinclair E, Epling L, Teague J, Jacobson MA, Tracy RP, Corey L, Deeks SG -
Tryptophan catabolism by indoleamine 2,3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV disease.
Science translational medicine 2010 Favre D, Mold J, Hunt PW, Kanwar B, Loke P, Seu L, Barbour JD, Lowe MM, Jayawardene A, Aweeka F, Huang Y, Douek DC, Brenchley JM, Martin JN, Hecht FM, Deeks SG, McCune JM -
Relationship between T cell activation and CD4+ T cell count in HIV-seropositive individuals with undetectable plasma HIV RNA levels in the absence of therapy.
The Journal of infectious diseases 2008 Hunt PW, Brenchley J, Sinclair E, McCune JM, Roland M, Page-Shafer K, Hsue P, Emu B, Krone M, Lampiris H, Douek D, Martin JN, Deeks SG -
Increased carotid intima-media thickness in HIV patients is associated with increased cytomegalovirus-specific T-cell responses.
AIDS (London, England) 2006 Hsue PY, Hunt PW, Sinclair E, Bredt B, Franklin A, Killian M, Hoh R, Martin JN, McCune JM, Waters DD, Deeks SG -
T cell activation is associated with lower CD4+ T cell gains in human immunodeficiency virus-infected patients with sustained viral suppression during antiretroviral therapy.
The Journal of infectious diseases 2003 Hunt PW, Martin JN, Sinclair E, Bredt B, Hagos E, Lampiris H, Deeks SG
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Genetic factors associated with age-related macular degeneration modulating plasma inflammatory biomarker levels in patients with AIDS.
Ophthalmic genetics 2024 Sezgin E, Schneider MF, Hunt PW, Beck-Engeser G, Ambayac GC, Jabs DA -
High-parameter phenotypic characterization reveals a subset of human Th17 cells that preferentially produce IL17 against M. tuberculosis antigen.
bioRxiv : the preprint server for biology 2024 Ogongo P, Tran A, Marzan F, Gingrich D, Krone M, Aweeka F, Lindestam Arlehamn CS, Martin JN, Deeks SG, Hunt PW, Ernst JD -
Venous Thromboembolism Among People With HIV: Design, Implementation, and Findings of a Centralized Adjudication System in Clinical Care Sites Across the United States.
Journal of acquired immune deficiency syndromes (1999) 2024 Crane HM, Nance RM, Ruderman SA, Haidar L, Tenforde MW, Heckbert SR, Budoff MJ, Hahn AW, Drumright LN, Ma J, Mixson LS, Lober WB, Barnes GS, McReynolds J, Attia EF, Peter I, Moges T, Bamford L, Cachay… -
Sex and HIV Differences in Preserved Ratio Impaired Spirometry (PRISm) Among Ugandans Postpneumonia.
Open forum infectious diseases 2024 Abelman RA, Fitzpatrick J, Byanova KL, Zawedde J, Sanyu I, Byanyima P, Musisi E, Hsieh J, Zhang M, Branchini J, Sessolo A, Hunt PW, Lalitha R, Davis JL, Crothers K, Worodria W, Huang L -
Association of Intermediate-Stage Age-Related Macular Degeneration with Plasma Inflammatory Biomarkers in Persons with AIDS.
Ophthalmology science 2023 Jabs DA, Schneider MF, Pak JW, Beck-Engeser G, Chan F, Ambayec GC, Hunt PW -
Estimating the contribution of CD4 T cell subset proliferation and differentiation to HIV persistence.
Nature communications 2023 Reeves DB, Bacchus-Souffan C, Fitch M, Abdel-Mohsen M, Hoh R, Ahn H, Stone M, Hecht F, Martin J, Deeks SG, Hellerstein MK, McCune JM, Schiffer JT, Hunt PW -
Antiretroviral Therapy Intensification for Neurocognitive Impairment in Human Immunodeficiency Virus.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2023 Letendre SL, Chen H, McKhann A, Roa J, Vecchio A, Daar ES, Berzins B, Hunt PW, Marra CM, Campbell TB, Coombs RW, Ma Q, Swaminathan S, Macatangay BJC, Morse GD, Miller T, Rusin D, Greninger AL, Ha B, … -
Biological and Clinical Implications of the Vascular Endothelial Growth Factor Coreceptor Neuropilin-1 in Human Immunodeficiency Virus.
Open forum infectious diseases 2023 Schnittman SR, Kolossváry M, Beck-Engeser G, Fitch KV, Ambayec GC, Nance RM, Zanni MV, Diggs M, Chan F, McCallum S, Toribio M, Bamford L, Fichtenbaum CJ, Eron JJ, Jacobson JM, Mayer KH, Malvestutto C,… -
Plasma Interleukin-6 (IL-6), Angiopoietin-2, and C-Reactive Protein Levels Predict Subsequent Type 1 Myocardial Infarction in Persons With Treated HIV Infection.
Journal of acquired immune deficiency syndromes (1999) 2023 Graham SM, Nance RM, Chen J, Wurfel MM, Hunt PW, Heckbert SR, Budoff MJ, Moore RD, Jacobson JM, Martin JN, Crane HM, López JA, Liles WC -
Impact of Kaposi Sarcoma on Quality of Life Amongst HIV-infected Adults Initiating Antiretroviral Therapy in East Africa.
medRxiv : the preprint server for health sciences 2023 Scott L, Laker-Oketta M, Byakwaga H, Glidden D, Mwebesa B, Muzoora C, Maurer T, Assenzio M, Hunt P, Bangsberg D, Haberer J, Martin J -
Isolated abnormal diffusing capacity for carbon monoxide (iso↓DLco) is associated with increased respiratory symptom burden in people with HIV infection.
PloS one 2023 Byanova KL, Fitzpatrick J, Jan AK, McGing M, Hartman-Filson M, Farr CK, Zhang M, Gardner K, Branchini J, Kerruish R, Bhide S, Bates A, Hsieh J, Abelman R, Hunt PW, Wang RJ, Crothers KA, Huang L -
Effect of Immune-Modulatory Interventions on Asymptomatic Cytomegalovirus Shedding During Suppressive Antiretroviral Therapy.
The Journal of infectious diseases 2023 Hastie E, Moser C, Sun X, Lennox J, Hsue PY, Bosch RJ, Deeks S, Meneses MV, Lederman MM, Hunt P, Henrich TJ, Marconi VC, Gianella S -
Sex modifies the risk of HIV-associated obstructive lung disease in Ugandans postpneumonia.
AIDS (London, England) 2023 Abelman RA, Fitzpatrick J, Zawedde J, Sanyu I, Byanyima P, Kaswabuli S, Musisi E, Hsieh J, Gardner K, Zhang M, Byanova KL, Sessolo A, Hunt PW, Lalitha R, Davis JL, Crothers K, Worodria W, Huang L -
Polygenic risk scores point toward potential genetic mechanisms of type 2 myocardial infarction in people with HIV.
International journal of cardiology 2023 Lee WJ, Cheng H, Whitney BM, Nance RM, Britton SR, Jordahl K, Lindstrom S, Ruderman SA, Kitahata MM, Saag MS, Willig AL, Burkholder G, Eron JJ, Kovacic JC, Björkegren JLM, Mathews WC, Cachay E, … -
Beyond Undetectable: Modeling the Clinical Benefit of Improved Antiretroviral Adherence in Persons With Human Immunodeficiency Virus With Virologic Suppression.
Open forum infectious diseases 2023 Castillo-Mancilla JR, Morrow M, Hunt PW, Schnittman SR, Phillips AN, Baker JV, Haberer JE, Janeiro MJ, Aragao F, Cohen C, Musinguzi N, Brown TT, Cavassini M, Glass TR, Serrano-Villar S, Mawhinney S, … -
Pro-inflammatory and pro-resolving lipid mediators of inflammation in HIV: effect of aspirin intervention.
EBioMedicine 2023 Dalli J, Kitch D, O'Brien MP, Hunt PW, Funderburg N, Moisi D, Gupta A, Brown TT, Tien PC, Aberg JA, Shivakoti R -
Chronic viral coinfections differentially affect the likelihood of developing long COVID.
The Journal of clinical investigation 2023 Peluso MJ, Deveau TM, Munter SE, Ryder D, Buck A, Beck-Engeser G, Chan F, Lu S, Goldberg SA, Hoh R, Tai V, Torres L, Iyer NS, Deswal M, Ngo LH, Buitrago M, Rodriguez A, Chen JY, Yee BC, Chenna A, … -
Subclinical cardiac disease in children with perinatally acquired HIV is associated with inflammation.
AIDS (London, England) 2022 Masenga SK, Côté HCF, Hunt PW -
Factors Associated With Severity of COVID-19 Disease in a Multicenter Cohort of People With HIV in the United States, March-December 2020.
Journal of acquired immune deficiency syndromes (1999) 2022 Shapiro AE, Bender Ignacio RA, Whitney BM, Delaney JA, Nance RM, Bamford L, Wooten D, Keruly JC, Burkholder G, Napravnik S, Mayer KH, Webel AR, Kim HN, Van Rompaey SE, Christopoulos K, Jacobson J, … -
Impact of Pre-Existing Chronic Viral Infection and Reactivation on the Development of Long COVID.
medRxiv : the preprint server for health sciences 2022 Peluso MJ, Deveau TM, Munter SE, Ryder D, Buck A, Beck-Engeser G, Chan F, Lu S, Goldberg SA, Hoh R, Tai V, Torres L, Iyer NS, Deswal M, Ngo LH, Buitrago M, Rodriguez A, Chen JY, Yee BC, Chenna A, … -
Postacute sequelae and adaptive immune responses in people with HIV recovering from SARS-COV-2 infection.
AIDS (London, England) 2022 Peluso MJ, Spinelli MA, Deveau TM, Forman CA, Munter SE, Mathur S, Tang AF, Lu S, Goldberg SA, Arreguin MI, Hoh R, Tai V, Chen JY, Martinez EO, Yee BC, Chenna A, Winslow JW, Petropoulos CJ, Sette A, … -
Multiple substance use, inflammation and cardiac stretch in women living with HIV.
Drug and alcohol dependence 2022 Riley ED, Kizer JR, Tien PC, Vittinghoff E, Lynch KL, Wu AHB, Coffin PO, Beck-Engeser G, Braun C, Hunt PW -
LOXL-2 and TNC-C are markers of liver fibrogenesis in HCV/HIV-, HIV- and HCV-infected patients.
Biomarkers in medicine 2022 Altinbas A, Holmes JA, Salloum S, Lidofsky A, Alatrakchi N, Somsouk M, Hunt P, Deeks S, Chew KW, Lauer G, Kruger A, Lin W, Chung RT -
Attenuated HIV-1 Nef But Not Vpu Function in a Cohort of Rwandan Long-Term Survivors.
Frontiers in virology 2022 Umviligihozo G, Mann JK, Jin SW, Mwimanzi FM, Hsieh HA, Sudderuddin H, Lee GQ, Byakwaga H, Muzoora C, Hunt PW, Martin JN, Haberer JE, Karita E, Allen S, Hunter E, Brumme ZL, Brockman MA -
Plasma Markers of Neurologic Injury and Inflammation in People With Self-Reported Neurologic Postacute Sequelae of SARS-CoV-2 Infection.
Neurology(R) neuroimmunology & neuroinflammation 2022 Peluso MJ, Sans HM, Forman CA, Nylander AN, Ho HE, Lu S, Goldberg SA, Hoh R, Tai V, Munter SE, Chenna A, Yee BC, Winslow JW, Petropoulos CJ, Martin JN, Kelly JD, Durstenfeld MS, Hsue PY, Hunt PW, … -
Predictive value of CD8+ T cell and CD4/CD8 ratio at two years of successful ART in the risk of AIDS and non-AIDS events.
EBioMedicine 2022 Serrano-Villar S, Wu K, Hunt PW, Lok JJ, Ron R, Sainz T, Moreno S, Deeks SG, Bosch RJ -
A cytotoxic-skewed immune set point predicts low neutralizing antibody levels after Zika virus infection.
Cell reports 2022 McCarthy EE, Odorizzi PM, Lutz E, Smullin CP, Tenvooren I, Stone M, Simmons G, Hunt PW, Feeney ME, Norris PJ, Busch MP, Spitzer MH, Rutishauser RL -
Racial and ethnic disparities in coronavirus disease 2019 disease incidence independent of comorbidities, among people with HIV in the United States.
AIDS (London, England) 2022 Bender Ignacio RA, Shapiro AE, Nance RM, Whitney BM, Delaney JAC, Bamford L, Wooten D, Karris MY, Mathews WC, Kim HN, Keruly J, Burkholder G, Napravnik S, Mayer KH, Jacobson J, Saag M, Moore RD, Eron … -
Plasma CD16+ Extracellular Vesicles Associate with Carotid Artery Intima-Media Thickness in HIV+ Adults on Combination Antiretroviral Therapy.
mBio 2022 Marques de Menezes EG, Deng X, Liu J, Bowler SA, Shikuma CM, Stone M, Hunt PW, Ndhlovu LC, Norris PJ -
The HIV-1 proviral landscape reveals that Nef contributes to HIV-1 persistence in effector memory CD4+ T cells.
The Journal of clinical investigation 2022 Duette G, Hiener B, Morgan H, Mazur FG, Mathivanan V, Horsburgh BA, Fisher K, Tong O, Lee E, Ahn H, Shaik A, Fromentin R, Hoh R, Bacchus-Souffan C, Nasr N, Cunningham AL, Hunt PW, Chomont N, Turville … -
Tobacco smoking and binge alcohol use are associated with incident venous thromboembolism in an HIV cohort.
HIV medicine 2022 Luu B, Ruderman S, Nance R, Delaney JAC, Ma J, Hahn A, Heckbert SR, Budoff MJ, Crothers K, Mathews WC, Christopolous K, Hunt PW, Eron J, Moore R, Keruly J, Lober WB, Burkholder GA, Willig A, Chander G… -
Alcohol Consumption and Tryptophan Metabolism Among People with HIV Prior to Antiretroviral Therapy Initiation: The Uganda ARCH Cohort Study.
Alcohol and alcoholism (Oxford, Oxfordshire) 2022 Pierre F, Forman LS, Winter M, Cheng D, Ngabirano C, Emenyonu N, Hunt PW, Huang Y, Muyindike W, Samet J, Hahn JA, So-Armah K -
IFN-α blockade during ART-treated SIV infection lowers tissue vDNA, rescues immune function, and improves overall health.
JCI insight 2022 Swainson LA, Sharma AA, Ghneim K, Ribeiro SP, Wilkinson P, Dunham RM, Albright RG, Wong S, Estes JD, Piatak M, Deeks SG, Hunt PW, Sekaly RP, McCune JM -
Association of elevated plasma inflammatory biomarker levels with age-related macular degeneration but not cataract in persons with AIDS.
AIDS (London, England) 2022 Jabs DA, Van Natta ML, Schneider MF, Pak JW, Trang G, Jones NG, Milush J, Hunt PW -
Randomized Trial of Ruxolitinib in Antiretroviral-Treated Adults With Human Immunodeficiency Virus.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2022 Marconi VC, Moser C, Gavegnano C, Deeks SG, Lederman MM, Overton ET, Tsibris A, Hunt PW, Kantor A, Sekaly RP, Tressler R, Flexner C, Hurwitz SJ, Moisi D, Clagett B, Hardin WR, Del Rio C, Schinazi RF, … -
Is France Once Again Looking for a Scapegoat?
Pathogens & immunity 2021 Lederman MM, Flier JS, Hale P, Haase AT, Powderly W, Reiss P, Silvestri G, Sekaly RP, Paiardini M, Weissman D, Kuritzkes DR, Calabrese LH, Agre P, Reyes-Teran G, Landay AL, Lewin S, Richman DD, … -
Racial and ethnic disparities in COVID-19 disease incidence independent of comorbidities, among people with HIV in the US.
medRxiv : the preprint server for health sciences 2021 Bender Ignacio RA, Shapiro AE, Nance RM, Whitney BM, Delaney J, Bamford L, Wooten D, Karris M, Mathews WC, Kim HN, Van Rompaey SE, Keruly JC, Burkholder G, Napravnik S, Mayer KH, Jacobson J, Saag MS, … -
Markers of Immune Activation and Inflammation in Individuals With Postacute Sequelae of Severe Acute Respiratory Syndrome Coronavirus 2 Infection.
The Journal of infectious diseases 2021 Peluso MJ, Lu S, Tang AF, Durstenfeld MS, Ho HE, Goldberg SA, Forman CA, Munter SE, Hoh R, Tai V, Chenna A, Yee BC, Winslow JW, Petropoulos CJ, Greenhouse B, Hunt PW, Hsue PY, Martin JN, Daniel Kelly … -
Objective Identification of Cannabis Use Levels in Clinical Populations Is Critical for Detecting Pharmacological Outcomes.
Cannabis and cannabinoid research 2021 Huang W, Czuba LC, Manuzak JA, Martin JN, Hunt PW, Klatt NR, Isoherranen N -
Gag p24 Is a Marker of Human Immunodeficiency Virus Expression in Tissues and Correlates With Immune Response.
The Journal of infectious diseases 2021 Wu G, Zuck P, Goh SL, Milush JM, Vohra P, Wong JK, Somsouk M, Yukl SA, Shacklett BL, Chomont N, Haase AT, Hatano H, Schacker TW, Deeks SG, Hazuda DJ, Hunt PW, Howell BJ -
Internalized stigma, depressive symptoms, and the modifying role of antiretroviral therapy: A cohort study in rural Uganda.
SSM. Mental health 2021 Bebell LM, Kembabazi A, Musinguzi N, Martin JN, Hunt PW, Boum Y, O'Laughlin KN, Muzoora C, Haberer JE, Bwana MB, Bangsberg DR, Siedner MJ, Tsai AC -
Factors associated with severity of COVID-19 disease in a multicenter cohort of people with HIV in the United States, March-December 2020.
medRxiv : the preprint server for health sciences 2021 Shapiro AE, Bender Ignacio RA, Whitney BM, Delaney JA, Nance RM, Bamford L, Wooten D, Keruly JC, Burkholder G, Napravnik S, Mayer KH, Webel AR, Kim HN, Van Rompaey SE, Christopoulos K, Jacobson J, … -
HIV-1 Genomes Are Enriched in Memory CD4+ T-Cells with Short Half-Lives.
mBio 2021 Morcilla V, Bacchus-Souffan C, Fisher K, Horsburgh BA, Hiener B, Wang XQ, Schlub TE, Fitch M, Hoh R, Hecht FM, Martin JN, Deeks SG, Hellerstein MK, McCune JM, Hunt PW, Palmer S -
Association between cytomegalovirus infection, reduced gray matter volume, and resting-state functional hypoconnectivity in major depressive disorder: a replication and extension.
Translational psychiatry 2021 Zheng H, Ford BN, Kuplicki R, Burrows K, Hunt PW, Bodurka J, Kent Teague T, Irwin MR, Yolken RH, Paulus MP, Savitz J -
Treated HIV Infection and Progression of Carotid Atherosclerosis in Rural Uganda: A Prospective Observational Cohort Study.
Journal of the American Heart Association 2021 Siedner MJ, Bibangambah P, Kim JH, Lankowski A, Chang JL, Yang IT, Kwon DS, North CM, Triant VA, Longenecker C, Ghoshhajra B, Peck RN, Sentongo RN, Gilbert R, Kakuhikire B, Boum Y, Haberer JE, Martin … -
Markers of inflammation and immune activation are associated with lung function in a multi-center cohort of persons with HIV.
AIDS (London, England) 2021 Jan AK, Moore JV, Wang RJ, Mcging M, Farr CK, Moisi D, Hartman-Filson M, Kerruish R, Jeon D, Lewis E, Crothers K, Lederman MM, Hunt PW, Huang L -
Pre-treatment integrase inhibitor resistance is uncommon in antiretroviral therapy-naive individuals with HIV-1 subtype A1 and D infections in Uganda.
AIDS (London, England) 2021 McCluskey SM, Kamelian K, Musinguzi N, Kigozi S, Boum Y, Bwana MB, Muzoora C, Brumme ZL, Carrington M, Carlson J, Foley B, Hunt PW, Martin JN, Bangsberg DR, Harrigan PR, Siedner MJ, Haberer JE, Lee GQ -
Changes in Immune Activation During Pregnancy and the Postpartum Period in Treated HIV Infection.
Open forum infectious diseases 2021 Schnittman SR, Byakwaga H, Boum Y, Kabakyenga J, Matthews LT, Burdo TH, Huang Y, Tracy RP, Haberer JE, Kembabazi A, Kaida A, Moisi D, Lederman MM, Bangsberg DR, Martin JN, Hunt PW -
Correction to: Genetic architecture of cardiometabolic risks in people living with HIV.
BMC medicine 2021 Cheng H, Sewda A, Marquez-Luna C, White SR, Whitney BM, Williams-Nguyen J, Nance RM, Lee WJ, Kitahata MM, Saag MS, Willig A, Eron JJ, Mathews WC, Hunt PW, Moore RD, Webel A, Mayer KH, Delaney JA, … -
Clinical consequences of asymptomatic cytomegalovirus in treated human immunodeficency virus infection.
Current opinion in HIV and AIDS 2021 Schnittman SR, Hunt PW -
TCF-1 regulates HIV-specific CD8+ T cell expansion capacity.
JCI insight 2021 Rutishauser RL, Deguit CDT, Hiatt J, Blaeschke F, Roth TL, Wang L, Raymond KA, Starke CE, Mudd JC, Chen W, Smullin C, Matus-Nicodemos R, Hoh R, Krone M, Hecht FM, Pilcher CD, Martin JN, Koup RA, Douek… -
Replicable association between human cytomegalovirus infection and reduced white matter fractional anisotropy in major depressive disorder.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2021 Zheng H, Bergamino M, Ford BN, Kuplicki R, Yeh FC, Bodurka J, Burrows K, Tulsa 1000 Investigators, Hunt PW, Teague TK, Irwin MR, Yolken RH, Paulus MP, Savitz J -
Relationship between CD4 T cell turnover, cellular differentiation and HIV persistence during ART.
PLoS pathogens 2021 Bacchus-Souffan C, Fitch M, Symons J, Abdel-Mohsen M, Reeves DB, Hoh R, Stone M, Hiatt J, Kim P, Chopra A, Ahn H, York VA, Cameron DL, Hecht FM, Martin JN, Yukl SA, Mallal S, Cameron PU, Deeks SG, … -
Association Between Immunoglobulin E Levels and Kaposi Sarcoma in African Adults With Human Immunodeficiency Virus Infection.
The Journal of infectious diseases 2021 Byakwaga H, Barbachano-Guerrero A, Wang D, McAllister S, Naphri K, Laker-Oketta M, Muzoora C, Hunt PW, Martin J, King CA -
Accumulation of HIV-1 Drug Resistance Mutations and Methamphetamine Use.
Current HIV research 2021 Truong HM, Fatch R, Deeks SG, Krone M, Martin JN, Hunt PW, Lum PJ -
NIH Workshop on HIV-Associated Comorbidities, Coinfections, and Complications: Summary and Recommendation for Future Research.
Journal of acquired immune deficiency syndromes (1999) 2021 Pahwa S, Deeks S, Zou S, Tomitch N, Miller-Novak L, Caler E, Justice A, Sacktor N, Gabuzda D, Hunt PW, Brown T, Kurth A, Baral S, Mugavero M, Mayer KH, Mendenhall E, Detels R, Mutabazi V -
Shared Mechanisms Govern HIV Transcriptional Suppression in Circulating CD103+ and Gut CD4+ T Cells.
Journal of virology 2020 Yukl SA, Khan S, Chen TH, Trapecar M, Wu F, Xie G, Telwatte S, Fulop D, Pico AR, Laird GM, Ritter KD, Jones NG, Lu CM, Siliciano RF, Roan NR, Milush JM, Somsouk M, Deeks SG, Hunt PW, Sanjabi S -
A hidden menace? Cytomegalovirus infection is associated with reduced cortical gray matter volume in major depressive disorder.
Molecular psychiatry 2020 Zheng H, Ford BN, Bergamino M, Kuplicki R, Tulsa 1000 Investigators, Hunt PW, Bodurka J, Teague TK, Irwin MR, Yolken RH, Paulus MP, Savitz J -
Mechanistic differences underlying HIV latency in the gut and blood contribute to differential responses to latency-reversing agents.
AIDS (London, England) 2020 Telwatte S, Kim P, Chen TH, Milush JM, Somsouk M, Deeks SG, Hunt PW, Wong JK, Yukl SA -
Genetic architecture of cardiometabolic risks in people living with HIV.
BMC medicine 2020 Cheng H, Sewda A, Marquez-Luna C, White SR, Whitney BM, Williams-Nguyen J, Nance RM, Lee WJ, Kitahata MM, Saag MS, Willig A, Eron JJ, Mathews WC, Hunt PW, Moore RD, Webel A, Mayer KH, Delaney JA, … -
Phenotypic analysis of the unstimulated in vivo HIV CD4 T cell reservoir.
eLife 2020 Neidleman J, Luo X, Frouard J, Xie G, Hsiao F, Ma T, Morcilla V, Lee A, Telwatte S, Thomas R, Tamaki W, Wheeler B, Hoh R, Somsouk M, Vohra P, Milush J, James KS, Archin NM, Hunt PW, Deeks SG, Yukl SA,… -
Variation in HIV-1 Nef function within and among viral subtypes reveals genetically separable antagonism of SERINC3 and SERINC5.
PLoS pathogens 2020 Jin SW, Mwimanzi FM, Mann JK, Bwana MB, Lee GQ, Brumme CJ, Hunt PW, Martin JN, Bangsberg DR, Ndung'u T, Brumme ZL, Brockman MA -
Differential Vpu-Mediated CD4 and Tetherin Downregulation Functions among Major HIV-1 Group M Subtypes.
Journal of virology 2020 Umviligihozo G, Cobarrubias KD, Chandrarathna S, Jin SW, Reddy N, Byakwaga H, Muzoora C, Bwana MB, Lee GQ, Hunt PW, Martin JN, Brumme CJ, Bangsberg DR, Karita E, Allen S, Hunter E, Ndung'u T, Brumme … -
Pathogenesis of Aging and Age-related Comorbidities in People with HIV: Highlights from the HIV ACTION Workshop.
Pathogens & immunity 2020 Gabuzda D, Jamieson BD, Collman RG, Lederman MM, Burdo TH, Deeks SG, Dittmer DP, Fox HS, Funderburg NT, Pahwa SG, Pandrea I, Wilson CC, Hunt PW -
Association Between Chronic Hepatitis C Virus Infection and Myocardial Infarction Among People Living With HIV in the United States.
American journal of epidemiology 2020 Williams-Nguyen J, Hawes SE, Nance RM, Lindström S, Heckbert SR, Kim HN, Mathews WC, Cachay ER, Budoff M, Hurt CB, Hunt PW, Geng E, Moore RD, Mugavero MJ, Peter I, Kitahata MM, Saag MS, Crane HM, … -
Impact of first-line antiretroviral therapy regimens on the restoration of the CD4/CD8 ratio in the CNICS cohort.
The Journal of antimicrobial chemotherapy 2020 Herrera S, Fernandez-Felix BM, Hunt PW, Deeks SG, Sainz T, Heath SL, Achenbach CJ, Rodríguez B, Mathews C, Christopoulos K, Mayer K, Napravnik S, Moreno S, Serrano-Villar S -
Presence of asymptomatic cytomegalovirus and Epstein--Barr virus DNA in blood of persons with HIV starting antiretroviral therapy is associated with non-AIDS clinical events.
AIDS (London, England) 2020 Gianella S, Moser C, Vitomirov A, McKhann A, Layman L, Scott B, Caballero G, Lada S, Bosch RJ, Hoenigl M, Lurain N, Landay A, Lederman MM, Hunt PW, Smith D -
Antiretroviral Therapy Concentrations Differ in Gut vs. Lymph Node Tissues and Are Associated With HIV Viral Transcription by a Novel RT-ddPCR Assay.
Journal of acquired immune deficiency syndromes (1999) 2020 Lee SA, Telwatte S, Hatano H, Kashuba ADM, Cottrell ML, Hoh R, Liegler TJ, Stephenson S, Somsouk M, Hunt PW, Deeks SG, Yukl S, Savic RM -
Anemia risk factors among people living with HIV across the United States in the current treatment era: a clinical cohort study.
BMC infectious diseases 2020 Harding BN, Whitney BM, Nance RM, Ruderman SA, Crane HM, Burkholder G, Moore RD, Mathews WC, Eron JJ, Hunt PW, Volberding P, Rodriguez B, Mayer KH, Saag MS, Kitahata MM, Heckbert SR, Delaney JAC -
Antiretroviral drug class and anaemia risk in the current treatment era among people living with HIV in the USA: a clinical cohort study.
BMJ open 2020 Harding BN, Whitney BM, Nance RM, Crane HM, Burkholder G, Moore RD, Mathews WC, Eron JJ, Hunt PW, Volberding P, Rodriguez B, Mayer K, Saag MS, Kitahata MM, Heckbert SR, Delaney JAC -
Circulating CD30+CD4+ T Cells Increase Before Human Immunodeficiency Virus Rebound After Analytical Antiretroviral Treatment Interruption.
The Journal of infectious diseases 2020 Prator CA, Thanh C, Kumar S, Pan T, Peluso MJ, Bosch R, Jones N, Milush JM, Bakkour S, Stone M, Busch MP, Deeks SG, Hunt PW, Henrich TJ -
Super learner analysis of real-time electronically monitored adherence to antiretroviral therapy under constrained optimization and comparison to non-differentiated care approaches for persons living with HIV in rural Uganda.
Journal of the International AIDS Society 2020 Benitez AE, Musinguzi N, Bangsberg DR, Bwana MB, Muzoora C, Hunt PW, Martin JN, Haberer JE, Petersen ML -
Differential decay of intact and defective proviral DNA in HIV-1-infected individuals on suppressive antiretroviral therapy.
JCI insight 2020 Peluso MJ, Bacchetti P, Ritter KD, Beg S, Lai J, Martin JN, Hunt PW, Henrich TJ, Siliciano JD, Siliciano RF, Laird GM, Deeks SG -
HIV-1-induced cytokines deplete homeostatic innate lymphoid cells and expand TCF7-dependent memory NK cells.
Nature immunology 2020 Wang Y, Lifshitz L, Gellatly K, Vinton CL, Busman-Sahay K, McCauley S, Vangala P, Kim K, Derr A, Jaiswal S, Kucukural A, McDonel P, Hunt PW, Greenough T, Houghton J, Somsouk M, Estes JD, Brenchley JM,… -
Presence of asymptomatic CMV and EBV DNA in blood of persons with HIV starting antiretroviral therapy are associated with non-AIDS clinical events.
AIDS (London, England) 2020 Gianella S, Moser C, Vitomirov A, McKhann A, Layman L, Scott B, Caballero G, Lada S, Bosch RJ, Hoenigl M, Lurain N, Landay A, Lederman MM, Hunt PW, Smith D -
Impact of Antiretroviral Therapy Duration on HIV-1 Infection of T Cells within Anatomic Sites.
Journal of virology 2020 Lee E, von Stockenstrom S, Morcilla V, Odevall L, Hiener B, Shao W, Hartogensis W, Bacchetti P, Milush J, Liegler T, Sinclair E, Hatano H, Hoh R, Somsouk M, Hunt P, Boritz E, Douek D, Fromentin R, … -
Changes in the Fungal Marker β-D-Glucan After Antiretroviral Therapy and Association With Adiposity.
Open forum infectious diseases 2019 Dirajlal-Fargo S, Moser C, Rodriguez K, El-Kamari V, Funderburg NT, Bowman E, Brown TT, Hunt PW, Currier J, McComsey GA -
Antiretroviral Treatment of Acute HIV Infection Normalizes Levels of Cerebrospinal Fluid Markers of Central Nervous System (CNS) Inflammation: A Consequence of a Reduced CNS Reservoir?
The Journal of infectious diseases 2019 Gisslén M, Hunt PW -
Pneumoproteins are associated with pulmonary function in HIV-infected persons.
PloS one 2019 Jeon D, Chang EG, McGing M, Hartman-Filson M, Sommers M, Lewis E, Balmes JR, Moisi D, Lederman MM, Madsen KA, Woodruff PG, Hunt PW, Huang L, Inflammation, Aging, Microbes and Obstructive Lung Disease… -
Some Aspects of CD8+ T-Cell Exhaustion Are Associated With Altered T-Cell Mitochondrial Features and ROS Content in HIV Infection.
Journal of acquired immune deficiency syndromes (1999) 2019 Deguit CDT, Hough M, Hoh R, Krone M, Pilcher CD, Martin JN, Deeks SG, McCune JM, Hunt PW, Rutishauser RL -
Participating in Human Immunodeficiency Virus Cure Research at the End of Life.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2019 Vásquez JJ, Hunt PW -
Timing of Antiretroviral Therapy and Systemic Inflammation in Sub-Saharan Africa: Results From the META Longitudinal Cohort Study.
The Journal of infectious diseases 2019 Siedner MJ, Bwana MB, Asiimwe S, Amanyire G, Musinguzi N, Castillo-Mancilla J, Tracy RP, Katz IT, Bangsberg DR, Hunt PW, Orrell C, Haberer JE, META study investigators -
Association Between Bilirubin, Atazanavir, and Cardiovascular Disease Events Among People Living With HIV Across the United States.
Journal of acquired immune deficiency syndromes (1999) 2019 Crane HM, Nance RM, Heckbert SR, Ritchings C, Rosenblatt L, Budoff M, Wood BR, Tirschwell DL, Kim HN, Mathews WC, Geng E, Moore RD, Hunt PW, Eron JJ, Burkholder GA, Drozd DR, Chow FC, Becker KJ, Zunt … -
High Incidence of Intended Partner Pregnancy Among Men Living With HIV in Rural Uganda: Implications for Safer Conception Services.
Journal of acquired immune deficiency syndromes (1999) 2019 Kaida A, Kabakyenga J, Bwana M, Bajunirwe F, Muyindike W, Bennett K, Kembabazi A, Haberer JE, Boum Y, Martin JN, Hunt PW, Bangsberg DR, Matthews LT -
Mortality following myocardial infarction among HIV-infected persons: the Center for AIDS Research Network Of Integrated Clinical Systems (CNICS).
BMC medicine 2019 Feinstein MJ, Nance RM, Delaney JAC, Heckbert SR, Budoff MJ, Drozd DR, Burkholder GA, Willig JH, Mugavero MJ, Mathews WC, Moore RD, Eron JJ, Napravnik S, Hunt PW, Geng E, Hsue P, Peter I, Lober WB, … -
Association of Gut Intestinal Integrity and Inflammation with Insulin Resistance in Adults Living with HIV in Uganda.
AIDS patient care and STDs 2019 Reid MJA, Ma Y, Golovaty I, Okello S, Sentongo R, Feng M, Tsai AC, Kakuhikire B, Tracy R, Hunt PW, Siedner M, Tien PC -
HIV infection is associated with elevated biomarkers of immune activation in Ugandan adults with pneumonia.
PloS one 2019 Wang RJ, Moore J, Moisi D, Chang EG, Byanyima P, Kaswabuli S, Musisi E, Sanyu I, Sessolo A, Lalitha R, Worodria W, Davis JL, Crothers K, Lin J, Lederman MM, Hunt PW, Huang L -
CD32-RNA Co-localizes with HIV-RNA in CD3+ Cells Found within Gut Tissues from Viremic and ART-Suppressed Individuals.
Pathogens & immunity 2019 Vásquez JJ, Aguilar-Rodriguez BL, Rodriguez L, Hogan LE, Somsouk M, McCune JM, Deeks SG, Laszik ZG, Hunt PW, Henrich TJ -
Association of Systemic Inflammation With Retinal Vascular Caliber in Patients With AIDS.
Investigative ophthalmology & visual science 2019 Jabs DA, Van Natta ML, Trang G, Jones N, Milush JM, Cheu R, Klatt NR, Pak JW, Danis RP, Hunt PW -
Increased mucosal neutrophil survival is associated with altered microbiota in HIV infection.
PLoS pathogens 2019 Hensley-McBain T, Wu MC, Manuzak JA, Cheu RK, Gustin A, Driscoll CB, Zevin AS, Miller CJ, Coronado E, Smith E, Chang J, Gale M, Somsouk M, Burgener AD, Hunt PW, Hope TJ, Collier AC, Klatt NR -
Lower Pretreatment Gut Integrity Is Independently Associated With Fat Gain on Antiretroviral Therapy.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2019 El Kamari V, Moser C, Hileman CO, Currier JS, Brown TT, Johnston L, Hunt PW, McComsey GA -
Physical Activity Intensity is Associated with Symptom Distress in the CNICS Cohort.
AIDS and behavior 2019 Webel AR, Willig AL, Liu W, Sattar A, Boswell S, Crane HM, Hunt P, Kitahata M, Matthews WC, Saag MS, Lederman MM, Rodriguez B -
Cumulative Human Immunodeficiency Viremia, Antiretroviral Therapy, and Incident Myocardial Infarction.
Epidemiology (Cambridge, Mass.) 2019 Delaney JA, Nance RM, Whitney BM, Crane HM, Williams-Nguyen J, Feinstein MJ, Kaplan RC, Hanna DB, Budoff MJ, Drozd DR, Burkholder G, Mugavero MJ, Mathews WC, Moore RD, Eron JJ, Hunt PW, Geng E, Saag … -
Stimulant Use and Viral Suppression in the Era of Universal Antiretroviral Therapy.
Journal of acquired immune deficiency syndromes (1999) 2019 Carrico AW, Hunt PW, Neilands TB, Dilworth SE, Martin JN, Deeks SG, Riley ED -
Association of Age-related Macular Degeneration With Mortality in Patients With Acquired Immunodeficiency Syndrome; Role of Systemic Inflammation.
American journal of ophthalmology 2018 Jabs DA, Van Natta ML, Trang G, Jones NG, Milush JM, Cheu R, Klatt NR, Danis RP, Hunt PW -
Genotypic and Mechanistic Characterization of Subtype-Specific HIV Adaptation to Host Cellular Immunity.
Journal of virology 2018 Kinloch NN, Lee GQ, Carlson JM, Jin SW, Brumme CJ, Byakwaga H, Muzoora C, Bwana MB, Cobarrubias KD, Hunt PW, Martin JN, Carrington M, Bangsberg DR, Harrigan PR, Brockman MA, Brumme ZL -
Gut and blood differ in constitutive blocks to HIV transcription, suggesting tissue-specific differences in the mechanisms that govern HIV latency.
PLoS pathogens 2018 Telwatte S, Lee S, Somsouk M, Hatano H, Baker C, Kaiser P, Kim P, Chen TH, Milush J, Hunt PW, Deeks SG, Wong JK, Yukl SA -
Contraceptive use following unintended pregnancy among Ugandan women living with HIV.
PloS one 2018 Jarolimova J, Kabakyenga J, Bennett K, Muyindike W, Kembabazi A, Martin JN, Hunt PW, Boum Y, Haberer JE, Bangsberg DR, Kaida A, Matthews LT -
HIV DNA decay during antiretroviral therapy: lessons from a clinic-based cohort study.
AIDS (London, England) 2018 Jilg N, Hunt PW, Gandhi RT -
Macrophage Activation Marker Soluble CD163 Is a Dynamic Marker of Liver Fibrogenesis in Human Immunodeficiency Virus/Hepatitis C Virus Coinfection.
The Journal of infectious diseases 2018 Lidofsky A, Holmes JA, Feeney ER, Kruger AJ, Salloum S, Zheng H, Seguin IS, Altinbas A, Masia R, Corey KE, Gustafson JL, Schaefer EA, Hunt PW, Deeks S, Somsouk M, Chew KW, Chung RT, Alatrakchi N -
Prevalence and correlates of physical and sexual intimate partner violence among women living with HIV in Uganda.
PloS one 2018 Young CR, Kaida A, Kabakyenga J, Muyindike W, Musinguzi N, Martin JN, Hunt PW, Bangsberg DR, Haberer JE, Matthews LT -
Differentiation of Type 1 and Type 2 Myocardial Infarctions Among HIV-Infected Patients Requires Adjudication Due to Overlap in Risk Factors.
AIDS research and human retroviruses 2018 Nance RM, Crane HM, Ritchings C, Rosenblatt L, Budoff M, Heckbert SR, Drozd DR, Mathews WC, Geng E, Hunt PW, Feinstein MJ, Moore RD, Hsue P, Eron JJ, Burkholder GA, Rodriguez B, Mugavero MJ, Saag MS, … -
Brief Report: Systemic Inflammation, Immune Activation, and Impaired Lung Function Among People Living With HIV in Rural Uganda.
Journal of acquired immune deficiency syndromes (1999) 2018 North CM, Muyanja D, Kakuhikire B, Tsai AC, Tracy RP, Hunt PW, Kwon DS, Christiani DC, Okello S, Siedner MJ -
CYP2B6 Genetic Polymorphisms, Depression, and Viral Suppression in Adults Living with HIV Initiating Efavirenz-Containing Antiretroviral Therapy Regimens in Uganda: Pooled Analysis of Two Prospective Studies.
AIDS research and human retroviruses 2018 Chang JL, Lee SA, Tsai AC, Musinguzi N, Muzoora C, Bwana B, Boum Y, Haberer JE, Hunt PW, Martin J, Bangsberg DR, Kroetz DL, Siedner MJ -
Distribution and Performance of Cardiovascular Risk Scores in a Mixed Population of HIV-Infected and Community-Based HIV-Uninfected Individuals in Uganda.
Journal of acquired immune deficiency syndromes (1999) 2018 Muiru AN, Bibangambah P, Hemphill L, Sentongo R, Kim JH, Triant VA, Bangsberg DR, Tsai AC, Martin JN, Haberer JE, Boum Y, Plutzky J, Hunt PW, Okello S, Siedner MJ -
Increasing Prevalence of HIV Pretreatment Drug Resistance in Women But Not Men in Rural Uganda During 2005-2013.
AIDS patient care and STDs 2018 McCluskey SM, Lee GQ, Kamelian K, Kembabazi A, Musinguzi N, Bwana MB, Muzoora C, Haberer JE, Hunt PW, Martin JN, Boum Y, Bangsberg DR, Harrigan PR, Siedner MJ -
Depression and Suicidal Ideation Among HIV-Infected Adults Receiving Efavirenz Versus Nevirapine in Uganda: A Prospective Cohort Study.
Annals of internal medicine 2018 Chang JL, Tsai AC, Musinguzi N, Haberer JE, Boum Y, Muzoora C, Bwana M, Martin JN, Hunt PW, Bangsberg DR, Siedner MJ -
Heavy Cannabis Use Associated With Reduction in Activated and Inflammatory Immune Cell Frequencies in Antiretroviral Therapy-Treated Human Immunodeficiency Virus-Infected Individuals.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2018 Manuzak JA, Gott TM, Kirkwood JS, Coronado E, Hensley-McBain T, Miller C, Cheu RK, Collier AC, Funderburg NT, Martin JN, Wu MC, Isoherranen N, Hunt PW, Klatt NR -
Recent stimulant use and leukocyte gene expression in methamphetamine users with treated HIV infection.
Brain, behavior, and immunity 2018 Carrico AW, Flentje A, Kober K, Lee S, Hunt P, Riley ED, Shoptaw S, Flowers E, Dilworth SE, Pahwa S, Aouizerat BE -
Substance-associated elevations in monocyte activation among methamphetamine users with treated HIV infection.
AIDS (London, England) 2018 Carrico AW, Cherenack EM, Roach ME, Riley ED, Oni O, Dilworth SE, Shoptaw S, Hunt P, Roy S, Pallikkuth S, Pahwa S -
A20 upregulation during treated HIV disease is associated with intestinal epithelial cell recovery and function.
PLoS pathogens 2018 Chitre AS, Kattah MG, Rosli YY, Pao M, Deswal M, Deeks SG, Hunt PW, Abdel-Mohsen M, Montaner LJ, Kim CC, Ma A, Somsouk M, McCune JM -
Elucidating the Burden of HIV in Tissues Using Multiplexed Immunofluorescence and In Situ Hybridization: Methods for the Single-Cell Phenotypic Characterization of Cells Harboring HIV In Situ.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2018 Vasquez JJ, Hussien R, Aguilar-Rodriguez B, Junger H, Dobi D, Henrich TJ, Thanh C, Gibson E, Hogan LE, McCune J, Hunt PW, Stoddart CA, Laszik ZG -
Association of Retinal Vascular Caliber and Age-Related Macular Degeneration in Patients With the Acquired Immunodeficiency Syndrome.
Investigative ophthalmology & visual science 2018 Jabs DA, Van Natta ML, Pak JW, Danis RP, Hunt PW -
Can Biomarkers Advance HIV Research and Care in the Antiretroviral Therapy Era?
The Journal of infectious diseases 2018 Justice AC, Erlandson KM, Hunt PW, Landay A, Miotti P, Tracy RP -
Differential Expression of CD8+ T Cell Cytotoxic Effector Molecules in Blood and Gastrointestinal Mucosa in HIV-1 Infection.
Journal of immunology (Baltimore, Md. : 1950) 2018 Kiniry BE, Hunt PW, Hecht FM, Somsouk M, Deeks SG, Shacklett BL -
All About the Albumin? Prognostic Capacity of Serum Albumin in Patients With Treated HIV Infection.
The Journal of infectious diseases 2018 Siedner MJ, Hunt PW -
Inflammation investigated as a source of pharmacokinetic variability of atazanavir in AIDS Clinical Trials Group protocol A5224s.
Antiviral therapy 2018 Venuto CS, Lim J, Messing S, Hunt PW, McComsey GA, Morse GD -
Detection of HIV-1-specific gastrointestinal tissue resident CD8+ T-cells in chronic infection.
Mucosal immunology 2017 Kiniry BE, Li S, Ganesh A, Hunt PW, Somsouk M, Skinner PJ, Deeks SG, Shacklett BL -
Prevalence and clinical impacts of HIV-1 intersubtype recombinants in Uganda revealed by near-full-genome population and deep sequencing approaches.
AIDS (London, England) 2017 Lee GQ, Bangsberg DR, Mo T, Lachowski C, Brumme CJ, Zhang W, Lima VD, Boum Y, Mwebesa BB, Muzoora C, Andia I, Mbalibulha Y, Kembabazi A, Carroll R, Siedner MJ, Haberer JE, Mocello AR, Kigozi SH, Hunt … -
An Optimized and Validated Method for Isolation and Characterization of Lymphocytes from HIV+ Human Gut Biopsies.
AIDS research and human retroviruses 2017 Trapecar M, Khan S, Roan NR, Chen TH, Telwatte S, Deswal M, Pao M, Somsouk M, Deeks SG, Hunt PW, Yukl S, Sanjabi S -
Brief Report: Appraising Viral Load Thresholds and Adherence Support Recommendations in the World Health Organization Guidelines for Detection and Management of Virologic Failure.
Journal of acquired immune deficiency syndromes (1999) 2017 McCluskey SM, Boum Y, Musinguzi N, Haberer JE, Martin JN, Hunt PW, Marconi VC, Bangsberg DR, Siedner MJ -
Brief Report: Should Abacavir Be a First-Line Alternative for Adults With HIV in Sub-Saharan Africa?
Journal of acquired immune deficiency syndromes (1999) 2017 Lee GQ, McCluskey S, Boum Y, Hunt PW, Martin JN, Bangsberg DR, Gao X, Harrigan PR, Haberer JE, Siedner MJ -
MicroRNAs: novel tools to block gut inflammation in HIV?
AIDS (London, England) 2017 Klatt NR, Hunt PW -
Higher Body Mass Index Is Associated With Greater Proportions of Effector CD8+ T Cells Expressing CD57 in Women Living With HIV.
Journal of acquired immune deficiency syndromes (1999) 2017 Reid MJA, Baxi SM, Sheira LA, Landay AL, Frongillo EA, Adedimeji A, Cohen MH, Wentz E, Gustafson DR, Merenstein D, Hunt PW, Tien PC, Weiser SD, Women's Interagency HIV Study (WIHS) -
A Randomized Controlled Trial of Lisinopril to Decrease Lymphoid Fibrosis in Antiretroviral-Treated, HIV-infected Individuals.
Pathogens & immunity 2017 Cockerham LR, Yukl SA, Harvill K, Somsouk M, Joshi SK, Sinclair E, Liegler T, Hoh R, Lyons S, Hunt PW, Rupert A, Sereti I, Morcock DR, Rhodes A, Emson C, Hellerstein MK, Estes JD, Lewin S, Deeks SG, … -
Circulating LOXL2 Levels Reflect Severity of Intestinal Fibrosis and GALT CD4+ T Lymphocyte Depletion in Treated HIV Infection.
Pathogens & immunity 2017 Seang S, Somasunderam A, Nigalye M, Somsouk M, Schacker TW, Sanchez JL, Hunt PW, Utay NS, Lake JE -
Subtype-Specific Differences in Gag-Protease-Driven Replication Capacity Are Consistent with Intersubtype Differences in HIV-1 Disease Progression.
Journal of virology 2017 Kiguoya MW, Mann JK, Chopera D, Gounder K, Lee GQ, Hunt PW, Martin JN, Ball TB, Kimani J, Brumme ZL, Brockman MA, Ndung'u T -
Duration of Viral Suppression and Risk of Rebound Viremia with First-Line Antiretroviral Therapy in Rural Uganda.
AIDS and behavior 2017 Musinguzi N, Mocello RA, Boum Y, Hunt PW, Martin JN, Haberer JE, Bangsberg DR, Siedner MJ -
Limited engraftment of donor microbiome via one-time fecal microbial transplantation in treated HIV-infected individuals.
Gut microbes 2017 Vujkovic-Cvijin I, Rutishauser RL, Pao M, Hunt PW, Lynch SV, McCune JM, Somsouk M -
Cooking fuel and respiratory symptoms among people living with HIV in rural Uganda.
ERJ open research 2017 North CM, Valeri L, Hunt PW, Mocello AR, Martin JN, Boum Y, Haberer JE, Bangsberg DR, Christiani DC, Siedner MJ -
Incidence of Intermediate-stage Age-related Macular Degeneration in Patients With Acquired Immunodeficiency Syndrome.
American journal of ophthalmology 2017 Jabs DA, Van Natta ML, Pak JW, Danis RP, Hunt PW -
Correction: p16INK4a Expression and Immunologic Aging in Chronic HIV Infection.
PloS one 2017 Ribeiro SP, Milush JM, Cunha-Neto E, Kallas EG, Kalil J, Passero LFD, Hunt PW, Deeks SG, Nixon DF, SenGupta D -
Corrigendum: Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection.
Nature 2017 Doitsh G, Galloway NL, Geng X, Yang Z, Monroe KM, Zepeda O, Hunt PW, Hatano H, Sowinski S, Muñoz-Arias I, Greene WC -
Human Immunodeficiency Virus Persistence and T-Cell Activation in Blood, Rectal, and Lymph Node Tissue in Human Immunodeficiency Virus-Infected Individuals Receiving Suppressive Antiretroviral Therapy.
The Journal of infectious diseases 2017 Khoury G, Fromentin R, Solomon A, Hartogensis W, Killian M, Hoh R, Somsouk M, Hunt PW, Girling V, Sinclair E, Bacchetti P, Anderson JL, Hecht FM, Deeks SG, Cameron PU, Chomont N, Lewin SR -
Types of Myocardial Infarction Among Human Immunodeficiency Virus-Infected Individuals in the United States.
JAMA cardiology 2017 Crane HM, Paramsothy P, Drozd DR, Nance RM, Delaney JA, Heckbert SR, Budoff MJ, Burkholder GA, Willig JH, Mugavero MJ, Mathews WC, Crane PK, Moore RD, Eron JJ, Napravnik S, Hunt PW, Geng E, Hsue P, … -
Real-time electronic adherence monitoring plus follow-up improves adherence compared with standard electronic adherence monitoring.
AIDS (London, England) 2017 Haberer JE, Musinguzi N, Tsai AC, Boum Y, Bwana BM, Muzoora C, Hunt PW, Martin JN, Bangsberg DR -
D-Dimer Levels and Traditional Risk Factors Are Associated With Incident Hypertension Among HIV-Infected Individuals Initiating Antiretroviral Therapy in Uganda.
Journal of acquired immune deficiency syndromes (1999) 2016 Okello S, Asiimwe SB, Kanyesigye M, Muyindike WR, Boum Y, Mwebesa BB, Haberer JE, Huang Y, Williams K, Burdo TH, Tracy RP, Bangsberg DR, Mocello AR, Martin JN, Hunt PW, Siedner MJ -
Disease drivers of aging.
Annals of the New York Academy of Sciences 2016 Hodes RJ, Sierra F, Austad SN, Epel E, Neigh GN, Erlandson KM, Schafer MJ, LeBrasseur NK, Wiley C, Campisi J, Sehl ME, Scalia R, Eguchi S, Kasinath BS, Halter JB, Cohen HJ, Demark-Wahnefried W, Ahles … -
p16INK4a Expression and Immunologic Aging in Chronic HIV Infection.
PloS one 2016 Ribeiro SP, Milush JM, Cunha-Neto E, Kallas EG, Kalil J, Passero LFD, Hunt PW, Deeks SG, Nixon DF, SenGupta D -
Predominance of weakly cytotoxic, T-betLowEomesNeg CD8+ T-cells in human gastrointestinal mucosa: implications for HIV infection.
Mucosal immunology 2016 Kiniry BE, Ganesh A, Critchfield JW, Hunt PW, Hecht FM, Somsouk M, Deeks SG, Shacklett BL -
Very Early ART and Persistent Inflammation in Treated HIV.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2016 Hunt PW -
High-Sequence Diversity and Rapid Virus Turnover Contribute to Higher Rates of Coreceptor Switching in Treatment-Experienced Subjects with HIV-1 Viremia.
AIDS research and human retroviruses 2016 Nedellec R, Herbeck JT, Hunt PW, Deeks SG, Mullins JI, Anton ED, Reeves JD, Mosier DE -
Trends in one-year cumulative incidence of death between 2005 and 2013 among patients initiating antiretroviral therapy in Uganda.
International journal of STD & AIDS 2016 Bebell LM, Siedner MJ, Musinguzi N, Boum Y, Bwana BM, Muyindike W, Hunt PW, Martin JN, Bangsberg DR -
Ideal Cardiovascular Health and Carotid Atherosclerosis in a Mixed Cohort of HIV-Infected and Uninfected Ugandans.
AIDS research and human retroviruses 2016 Feinstein MJ, Kim JH, Bibangambah P, Sentongo R, Martin JN, Tsai AC, Bangsberg DR, Hemphill L, Triant VA, Boum Y, Hunt PW, Okello S, Siedner MJ -
Relationship Power and Sexual Violence Among HIV-Positive Women in Rural Uganda.
AIDS and behavior 2016 Conroy AA, Tsai AC, Clark GM, Boum Y, Hatcher AM, Kawuma A, Hunt PW, Martin JN, Bangsberg DR, Weiser SD -
Host genetic predictors of the kynurenine pathway of tryptophan catabolism among treated HIV-infected Ugandans.
AIDS (London, England) 2016 Lee SA, Mefford JA, Huang Y, Witte JS, Martin JN, Haas DW, Mclaren PJ, Mushiroda T, Kubo M, Byakwaga H, Hunt PW, Kroetz DL -
Non-R5-tropic HIV-1 in subtype A1 and D infections were associated with lower pretherapy CD4+ cell count but not with PI/(N)NRTI therapy outcomes in Mbarara, Uganda.
AIDS (London, England) 2016 Lee GQ, Lachowski C, Cai E, Lima VD, Boum Y, Muzoora C, Mocello AR, Hunt PW, Martin JN, Bangsberg DR, Harrigan PR -
Impact of early cART in the gut during acute HIV infection.
JCI insight 2016 Deleage C, Schuetz A, Alvord WG, Johnston L, Hao XP, Morcock DR, Rerknimitr R, Fletcher JL, Puttamaswin S, Phanuphak N, Dewar R, McCune JM, Sereti I, Robb M, Kim JH, Schacker TW, Hunt P, Lifson JD, … -
Soluble CD163 and Clinical Outcomes in Treated HIV Infection: Insights Into Mechanisms.
The Journal of infectious diseases 2016 Hunt PW -
IL-15 promotes activation and expansion of CD8+ T cells in HIV-1 infection.
The Journal of clinical investigation 2016 Younes SA, Freeman ML, Mudd JC, Shive CL, Reynaldi A, Panigrahi S, Estes JD, Deleage C, Lucero C, Anderson J, Schacker TW, Davenport MP, McCune JM, Hunt PW, Lee SA, Serrano-Villar S, Debernardo RL, … -
Immunologic profiles distinguish aviremic HIV-infected adults.
AIDS (London, England) 2016 Ramirez CM, Sinclair E, Epling L, Lee SA, Jain V, Hsue PY, Hatano H, Conn D, Hecht FM, Martin JN, McCune JM, Deeks SG, Hunt PW -
Immune Activation and HIV-Specific CD8(+) T Cells in Cerebrospinal Fluid of HIV Controllers and Noncontrollers.
AIDS research and human retroviruses 2016 Ganesh A, Lemongello D, Lee E, Peterson J, McLaughlin BE, Ferre AL, Gillespie GM, Fuchs D, Deeks SG, Hunt PW, Price RW, Spudich SS, Shacklett BL -
Bacteroides are associated with GALT iNKT cell function and reduction of microbial translocation in HIV-1 infection.
Mucosal immunology 2016 Paquin-Proulx D, Ching C, Vujkovic-Cvijin I, Fadrosh D, Loh L, Huang Y, Somsouk M, Lynch SV, Hunt PW, Nixon DF, SenGupta D -
HIV-Infected Ugandan Women on Antiretroviral Therapy Maintain HIV-1 RNA Suppression Across Periconception, Pregnancy, and Postpartum Periods.
Journal of acquired immune deficiency syndromes (1999) 2016 Matthews LT, Ribaudo HB, Kaida A, Bennett K, Musinguzi N, Siedner MJ, Kabakyenga J, Hunt PW, Martin JN, Boum Y, Haberer JE, Bangsberg DR -
Reply to Barrett, et al.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2016 Freeman ML, Mudd JC, Shive CL, Younes SA, Panigrahi S, Sieg SF, Lee SA, Hunt PW, Calabrese LH, Gianella S, Rodriguez B, Lederman MM -
Altered Virome and Bacterial Microbiome in Human Immunodeficiency Virus-Associated Acquired Immunodeficiency Syndrome.
Cell host & microbe 2016 Monaco CL, Gootenberg DB, Zhao G, Handley SA, Ghebremichael MS, Lim ES, Lankowski A, Baldridge MT, Wilen CB, Flagg M, Norman JM, Keller BC, Luévano JM, Wang D, Boum Y, Martin JN, Hunt PW, Bangsberg DR… -
Role of immune activation in progression to AIDS.
Current opinion in HIV and AIDS 2016 Utay NS, Hunt PW -
HIV infection and arterial stiffness among older-adults taking antiretroviral therapy in rural Uganda.
AIDS (London, England) 2016 Siedner MJ, Kim JH, Nakku RS, Hemphill L, Triant VA, Haberer JE, Martin JN, Boum Y, Kwon DS, Tsai AC, Hunt PW, Okello S, Bangsberg DR -
Duration of Antiretroviral Therapy Adherence Interruption Is Associated With Risk of Virologic Rebound as Determined by Real-Time Adherence Monitoring in Rural Uganda.
Journal of acquired immune deficiency syndromes (1999) 2015 Haberer JE, Musinguzi N, Boum Y, Siedner MJ, Mocello AR, Hunt PW, Martin JN, Bangsberg DR -
The Kynurenine Pathway of Tryptophan Catabolism and AIDS-Associated Kaposi Sarcoma in Africa.
Journal of acquired immune deficiency syndromes (1999) 2015 Byakwaga H, Hunt PW, Laker-Oketta M, Glidden DV, Huang Y, Bwana BM, Mocello AR, Bennett J, Walusansa V, Dollard SC, Bangsberg DR, Mbidde EK, Martin JN -
Unhealthy Alcohol Use is Associated with Monocyte Activation Prior to Starting Antiretroviral Therapy.
Alcoholism, clinical and experimental research 2015 Carrico AW, Hunt PW, Emenyonu NI, Muyindike W, Ngabirano C, Cheng DM, Winter MR, Samet JH, Hahn JA -
Incidence and predictors of hypertension in adults with HIV-initiating antiretroviral therapy in south-western Uganda.
Journal of hypertension 2015 Okello S, Kanyesigye M, Muyindike WR, Annex BH, Hunt PW, Haneuse S, Siedner MJ -
CD8 T-Cell Expansion and Inflammation Linked to CMV Coinfection in ART-treated HIV Infection.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2015 Freeman ML, Mudd JC, Shive CL, Younes SA, Panigrahi S, Sieg SF, Lee SA, Hunt PW, Calabrese LH, Gianella S, Rodriguez B, Lederman MM -
Persistent Immune Activation and Carotid Atherosclerosis in HIV-Infected Ugandans Receiving Antiretroviral Therapy.
The Journal of infectious diseases 2015 Siedner MJ, Kim JH, Nakku RS, Bibangambah P, Hemphill L, Triant VA, Haberer JE, Martin JN, Mocello AR, Boum Y, Kwon DS, Tracy RP, Burdo T, Huang Y, Cao H, Okello S, Bangsberg DR, Hunt PW -
Epigenetic mechanisms, T-cell activation, and CCR5 genetics interact to regulate T-cell expression of CCR5, the major HIV-1 coreceptor.
Proceedings of the National Academy of Sciences of the United States of America 2015 Gornalusse GG, Mummidi S, Gaitan AA, Jimenez F, Ramsuran V, Picton A, Rogers K, Manoharan MS, Avadhanam N, Murthy KK, Martinez H, Molano Murillo A, Chykarenko ZA, Hutt R, Daskalakis D, Shostakovich-… -
Second European Round Table on the Future Management of HIV: 10-11 October 2014, Barcelona, Spain.
Journal of virus eradication 2015 Rokx C, Richman DD, Müller-Trutwin M, Silvestri G, Lunzen J, Khoo S, Lichterfeld M, Altfeld M, Perno CF, Hunt PW, Mallon P, Rockstroh JK, Pozniak AL, Clotet B, Boucher CA -
Age at Entry Into Care, Timing of Antiretroviral Therapy Initiation, and 10-Year Mortality Among HIV-Seropositive Adults in the United States.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2015 Edwards JK, Cole SR, Westreich D, Mugavero MJ, Eron JJ, Moore RD, Mathews WC, Hunt P, Williams C, Centers for AIDS Research Network of Integrated Clinical Systems investigators -
The influence of partnership on contraceptive use among HIV-infected women accessing antiretroviral therapy in rural Uganda.
Contraception 2015 Nieves CI, Kaida A, Seage GR, Kabakyenga J, Muyindike W, Boum Y, Mocello AR, Martin JN, Hunt PW, Haberer JE, Bangsberg DR, Matthews LT -
Longitudinal Genetic Characterization Reveals That Cell Proliferation Maintains a Persistent HIV Type 1 DNA Pool During Effective HIV Therapy.
The Journal of infectious diseases 2015 von Stockenstrom S, Odevall L, Lee E, Sinclair E, Bacchetti P, Killian M, Epling L, Shao W, Hoh R, Ho T, Faria NR, Lemey P, Albert J, Hunt P, Loeb L, Pilcher C, Poole L, Hatano H, Somsouk M, Douek D, … -
CD41 T cell recovery during suppression of HIV replication: an international comparison of the immunological efficacy of antiretroviral therapy in North America, Asia and Africa.
International journal of epidemiology 2015 Geng EH, Neilands TB, Thièbaut R, Bwana MB, Nash D, Moore RD, Wood R, Zannou DM, Althoff KN, Lim PL, Nachega JB, Easterbrook PJ, Kambugu A, Little F, Nakigozi G, Nakanjako D, Kiggundu V, Ki Li PC, … -
Prospective Study of the Mental Health Consequences of Sexual Violence Among Women Living With HIV in Rural Uganda.
Journal of interpersonal violence 2015 Tsai AC, Wolfe WR, Kumbakumba E, Kawuma A, Hunt PW, Martin JN, Bangsberg DR, Weiser SD -
Gut epithelial barrier and systemic inflammation during chronic HIV infection.
AIDS (London, England) 2015 Somsouk M, Estes JD, Deleage C, Dunham RM, Albright R, Inadomi JM, Martin JN, Deeks SG, McCune JM, Hunt PW -
Persistent HIV-related stigma in rural Uganda during a period of increasing HIV incidence despite treatment expansion.
AIDS (London, England) 2015 Chan BT, Weiser SD, Boum Y, Siedner MJ, Mocello AR, Haberer JE, Hunt PW, Martin JN, Mayer KH, Bangsberg DR, Tsai AC -
Declining prevalence of probable depression among patients presenting for antiretroviral therapy in rural Uganda: the role of early treatment initiation.
AIDS and behavior 2015 Chan BT, Weiser SD, Boum Y, Haberer JE, Kembabazi A, Hunt PW, Martin JN, Mocello AR, Bangsberg DR, Tsai AC -
The factor structure and presentation of depression among HIV-positive adults in Uganda.
AIDS and behavior 2015 Psaros C, Haberer JE, Boum Y, Tsai AC, Martin JN, Hunt PW, Bangsberg DR, Safren SA -
The immunologic effects of mesalamine in treated HIV-infected individuals with incomplete CD4+ T cell recovery: a randomized crossover trial.
PloS one 2014 Somsouk M, Dunham RM, Cohen M, Albright R, Abdel-Mohsen M, Liegler T, Lifson J, Piatak M, Gorelick R, Huang Y, Wu Y, Hsue PY, Martin JN, Deeks SG, McCune JM, Hunt PW -
Comparison of self-reported alcohol consumption to phosphatidylethanol measurement among HIV-infected patients initiating antiretroviral treatment in southwestern Uganda.
PloS one 2014 Bajunirwe F, Haberer JE, Boum Y, Hunt P, Mocello R, Martin JN, Bangsberg DR, Hahn JA -
Depression during pregnancy and the postpartum among HIV-infected women on antiretroviral therapy in Uganda.
Journal of acquired immune deficiency syndromes (1999) 2014 Kaida A, Matthews LT, Ashaba S, Tsai AC, Kanters S, Robak M, Psaros C, Kabakyenga J, Boum Y, Haberer JE, Martin JN, Hunt PW, Bangsberg DR -
Reply to Cannizzo et al.
The Journal of infectious diseases 2014 Hunt PW -
Lymphoid fibrosis occurs in long-term nonprogressors and persists with antiretroviral therapy but may be reversible with curative interventions.
The Journal of infectious diseases 2014 Sanchez JL, Hunt PW, Reilly CS, Hatano H, Beilman GJ, Khoruts A, Jasurda JS, Somsouk M, Thorkelson A, Russ S, Anderson J, Deeks SG, Schacker TW -
Factors associated with CD8+ T-cell activation in HIV-1-infected patients on long-term antiretroviral therapy.
Journal of acquired immune deficiency syndromes (1999) 2014 Zheng L, Taiwo B, Gandhi RT, Hunt PW, Collier AC, Flexner C, Bosch RJ -
The CD8⁺ memory stem T cell (T(SCM)) subset is associated with improved prognosis in chronic HIV-1 infection.
Journal of virology 2014 Ribeiro SP, Milush JM, Cunha-Neto E, Kallas EG, Kalil J, Somsouk M, Hunt PW, Deeks SG, Nixon DF, SenGupta D -
Empiric deworming and CD4 count recovery in HIV-infected Ugandans initiating antiretroviral therapy.
PLoS neglected tropical diseases 2014 Lankowski AJ, Tsai AC, Kanyesigye M, Bwana M, Haberer JE, Wenger M, Martin JN, Bangsberg DR, Hunt PW, Siedner MJ -
The dynamic relationship between social support and HIV-related stigma in rural Uganda.
Annals of behavioral medicine : a publication of the Society of Behavioral Medicine 2014 Takada S, Weiser SD, Kumbakumba E, Muzoora C, Martin JN, Hunt PW, Haberer JE, Kawuma A, Bangsberg DR, Tsai AC -
Programmed death-1 expression on CD4⁺ and CD8⁺ T cells in treated and untreated HIV disease.
AIDS (London, England) 2014 Cockerham LR, Jain V, Sinclair E, Glidden DV, Hartogenesis W, Hatano H, Hunt PW, Martin JN, Pilcher CD, Sekaly R, McCune JM, Hecht FM, Deeks SG -
Prevalence and virologic consequences of transmitted HIV-1 drug resistance in Uganda.
AIDS research and human retroviruses 2014 Lee GQ, Bangsberg DR, Muzoora C, Boum Y, Oyugi JH, Emenyonu N, Bennett J, Hunt PW, Knapp D, Brumme CJ, Harrigan PR, Martin JN -
Antiretroviral therapy: stubborn limitations persist.
Lancet (London, England) 2014 Deeks SG, Hunt PW -
The authors reply.
American journal of epidemiology 2014 Crane HM, Heckbert SR, Drozd DR, Budoff MJ, Delaney JA, Rodriguez C, Paramsothy P, Lober WB, Burkholder G, Willig JH, Mugavero MJ, Mathews WC, Crane PK, Moore RD, Napravnik S, Eron JJ, Hunt P, Geng E,… -
HIV and aging: emerging research issues.
Current opinion in HIV and AIDS 2014 Hunt PW -
Tobacco use among adults initiating treatment for HIV infection in rural Uganda.
AIDS and behavior 2014 Kruse GR, Bangsberg DR, Hahn JA, Haberer JE, Hunt PW, Muzoora C, Bennett JP, Martin JN, Rigotti NA -
A closer look at hepatitis C clearance in HIV controllers: a response.
AIDS (London, England) 2014 Asher AK, Santos GM, Evans J, Dokubo EK, Lee TH, Martin JN, Deeks SG, Tobler LH, Busch M, Hunt PW, Page K -
CD4+ cell count at antiretroviral therapy initiation and economic restoration in rural Uganda.
AIDS (London, England) 2014 Venkataramani AS, Thirumurthy H, Haberer JE, Ii YB, Siedner MJ, Kembabazi A, Hunt PW, Martin JN, Bangsberg DR, Tsai AC -
HIV-infected individuals with low CD4/CD8 ratio despite effective antiretroviral therapy exhibit altered T cell subsets, heightened CD8+ T cell activation, and increased risk of non-AIDS morbidity and mortality.
PLoS pathogens 2014 Serrano-Villar S, Sainz T, Lee SA, Hunt PW, Sinclair E, Shacklett BL, Ferre AL, Hayes TL, Somsouk M, Hsue PY, Van Natta ML, Meinert CL, Lederman MM, Hatano H, Jain V, Huang Y, Hecht FM, Martin JN, … -
Soluble markers of inflammation and coagulation but not T-cell activation predict non-AIDS-defining morbid events during suppressive antiretroviral treatment.
The Journal of infectious diseases 2014 Tenorio AR, Zheng Y, Bosch RJ, Krishnan S, Rodriguez B, Hunt PW, Plants J, Seth A, Wilson CC, Deeks SG, Lederman MM, Landay AL -
Relationship of immunologic response to antiretroviral therapy with non-AIDS defining cancer incidence.
AIDS (London, England) 2014 Yanik EL, Napravnik S, Cole SR, Achenbach CJ, Gopal S, Dittmer DP, Olshan AF, Kitahata MM, Mugavero MJ, Saag M, Moore RD, Mathews WC, Hunt P, Eron JJ -
Point-of-care C-reactive protein testing to facilitate implementation of isoniazid preventive therapy for people living with HIV.
Journal of acquired immune deficiency syndromes (1999) 2014 Yoon C, Davis JL, Huang L, Muzoora C, Byakwaga H, Scibetta C, Bangsberg DR, Nahid P, Semitala FC, Hunt PW, Martin JN, Cattamanchi A -
Lessons learned from the design and implementation of myocardial infarction adjudication tailored for HIV clinical cohorts.
American journal of epidemiology 2014 Crane HM, Heckbert SR, Drozd DR, Budoff MJ, Delaney JA, Rodriguez C, Paramsothy P, Lober WB, Burkholder G, Willig JH, Mugavero MJ, Mathews WC, Crane PK, Moore RD, Napravnik S, Eron JJ, Hunt P, Geng E,… -
HIV viremia and incidence of non-Hodgkin lymphoma in patients successfully treated with antiretroviral therapy.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2014 Achenbach CJ, Buchanan AL, Cole SR, Hou L, Mugavero MJ, Crane HM, Moore RD, Haubrich RH, Gopal S, Eron JJ, Hunt PW, Rodriguez B, Mayer K, Saag MS, Kitahata MM, Centers for AIDS Research (CFAR) Network… -
Discordance between peripheral and colonic markers of inflammation during suppressive ART.
Journal of acquired immune deficiency syndromes (1999) 2014 Dunham RM, Vujkovic-Cvijin I, Yukl SA, Broadhurst MJ, Loke P, Albright RG, Wong JK, Lederman MM, Somsouk M, Hunt PW, Martin JN, Deeks SG, McCune JM -
A comparison of methods for measuring rectal HIV levels suggests that HIV DNA resides in cells other than CD4+ T cells, including myeloid cells.
AIDS (London, England) 2014 Yukl SA, Sinclair E, Somsouk M, Hunt PW, Epling L, Killian M, Girling V, Li P, Havlir DV, Deeks SG, Wong JK, Hatano H -
Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection.
Nature 2014 Doitsh G, Galloway NL, Geng X, Yang Z, Monroe KM, Zepeda O, Hunt PW, Hatano H, Sowinski S, Muñoz-Arias I, Greene WC -
Blunted response to combination antiretroviral therapy in HIV elite controllers: an international HIV controller collaboration.
PloS one 2014 Boufassa F, Lechenadec J, Meyer L, Costagliola D, Hunt PW, Pereyra F, Deeks S, Pancino G, Taulera O, Lichterfeld M, Delobel P, Saez-Cirion A, Lambotte O, ANRS CO18 HIV Controllers Cohort, Cascade … -
Treatment as long-term prevention: sustained reduction in HIV sexual transmission risk with use of antiretroviral therapy in rural Uganda.
AIDS (London, England) 2014 Siedner MJ, Musinguzi N, Tsai AC, Muzoora C, Kembabazi A, Weiser SD, Bennett J, Hunt PW, Martin JN, Haberer JE, Bangsberg DR -
Longitudinal assessment of associations between food insecurity, antiretroviral adherence and HIV treatment outcomes in rural Uganda.
AIDS (London, England) 2014 Weiser SD, Palar K, Frongillo EA, Tsai AC, Kumbakumba E, Depee S, Hunt PW, Ragland K, Martin J, Bangsberg DR -
Higher CD27+CD8+ T cells percentages during suppressive antiretroviral therapy predict greater subsequent CD4+ T cell recovery in treated HIV infection.
PloS one 2013 Seu L, Ortiz GM, Epling L, Sinclair E, Swainson LA, Bajpai UD, Huang Y, Deeks SG, Hunt PW, Martin JN, McCune JM -
Internalized stigma, social distance, and disclosure of HIV seropositivity in rural Uganda.
Annals of behavioral medicine : a publication of the Society of Behavioral Medicine 2013 Tsai AC, Bangsberg DR, Kegeles SM, Katz IT, Haberer JE, Muzoora C, Kumbakumba E, Hunt PW, Martin JN, Weiser SD -
The HIV-1 reservoir in eight patients on long-term suppressive antiretroviral therapy is stable with few genetic changes over time.
Proceedings of the National Academy of Sciences of the United States of America 2013 Josefsson L, von Stockenstrom S, Faria NR, Sinclair E, Bacchetti P, Killian M, Epling L, Tan A, Ho T, Lemey P, Shao W, Hunt PW, Somsouk M, Wylie W, Douek DC, Loeb L, Custer J, Hoh R, Poole L, Deeks SG… -
Genetic interplay between HLA-C and MIR148A in HIV control and Crohn disease.
Proceedings of the National Academy of Sciences of the United States of America 2013 Kulkarni S, Qi Y, O'hUigin C, Pereyra F, Ramsuran V, McLaren P, Fellay J, Nelson G, Chen H, Liao W, Bass S, Apps R, Gao X, Yuki Y, Lied A, Ganesan A, Hunt PW, Deeks SG, Wolinsky S, Walker BD, … -
Human leukocyte antigen B*57 does not fully explain hepatitis C clearance in HIV controllers.
AIDS (London, England) 2013 Asher AK, Santos GM, Evans J, Dokubo EK, Lee TH, Martin JN, Deeks SG, Tobler LH, Busch M, Hunt PW, Page K -
Comparative effectiveness of fish oil versus fenofibrate, gemfibrozil, and atorvastatin on lowering triglyceride levels among HIV-infected patients in routine clinical care.
Journal of acquired immune deficiency syndromes (1999) 2013 Muñoz MA, Liu W, Delaney JA, Brown E, Mugavero MJ, Mathews WC, Napravnik S, Willig JH, Eron JJ, Hunt PW, Kahn JO, Saag MS, Kitahata MM, Crane HM -
Prospective antiretroviral treatment of asymptomatic, HIV-1 infected controllers.
PLoS pathogens 2013 Hatano H, Yukl SA, Ferre AL, Graf EH, Somsouk M, Sinclair E, Abdel-Mohsen M, Liegler T, Harvill K, Hoh R, Palmer S, Bacchetti P, Hunt PW, Martin JN, McCune JM, Tracy RP, Busch MP, O'Doherty U, … -
HIV-infected women on antiretroviral treatment have increased mortality during pregnant and postpartum periods.
AIDS (London, England) 2013 Matthews LT, Kaida A, Kanters S, Byakwagamd H, Mocello AR, Muzoora C, Kembabazi A, Haberer JE, Martin JN, Bangsberg DR, Hunt PW -
How does antiretroviral treatment attenuate the stigma of HIV? Evidence from a cohort study in rural Uganda.
AIDS and behavior 2013 Tsai AC, Bangsberg DR, Bwana M, Haberer JE, Frongillo EA, Muzoora C, Kumbakumba E, Hunt PW, Martin JN, Weiser SD -
Response: Maraviroc intensification and microbial translocation.
Blood 2013 Hunt PW, Lederman MM, Deeks SG -
Ability of HIV-1 Nef to downregulate CD4 and HLA class I differs among viral subtypes.
Retrovirology 2013 Mann JK, Byakwaga H, Kuang XT, Le AQ, Brumme CJ, Mwimanzi P, Omarjee S, Martin E, Lee GQ, Baraki B, Danroth R, McCloskey R, Muzoora C, Bangsberg DR, Hunt PW, Goulder PJ, Walker BD, Harrigan PR, Martin… -
Comparison of HIV DNA and RNA in gut-associated lymphoid tissue of HIV-infected controllers and noncontrollers.
AIDS (London, England) 2013 Hatano H, Somsouk M, Sinclair E, Harvill K, Gilman L, Cohen M, Hoh R, Hunt PW, Martin JN, Wong JK, Deeks SG, Yukl SA -
Realtime adherence monitoring of antiretroviral therapy among HIV-infected adults and children in rural Uganda.
AIDS (London, England) 2013 Haberer JE, Kiwanuka J, Nansera D, Muzoora C, Hunt PW, So J, O'Donnell M, Siedner M, Martin JN, Bangsberg DR -
The impact of age on the prognostic capacity of CD8+ T-cell activation during suppressive antiretroviral therapy.
AIDS (London, England) 2013 Lok JJ, Hunt PW, Collier AC, Benson CA, Witt MD, Luque AE, Deeks SG, Bosch RJ -
AIDS alters the commensal plasma virome.
Journal of virology 2013 Li L, Deng X, Linsuwanon P, Bangsberg D, Bwana MB, Hunt P, Martin JN, Deeks SG, Delwart E -
Disinhibition in risky sexual behavior in men, but not women, during four years of antiretroviral therapy in rural, southwestern Uganda.
PloS one 2013 Kembabazi A, Bajunirwe F, Hunt PW, Martin JN, Muzoora C, Haberer JE, Bangsberg DR, Siedner MJ -
Immunosenescence is associated with presence of Kaposi's sarcoma in antiretroviral treated HIV infection.
AIDS (London, England) 2013 Unemori P, Leslie KS, Hunt PW, Sinclair E, Epling L, Mitsuyasu R, Effros RB, Dock J, Dollard SG, Deeks SG, Martin JN, Maurer TA -
Antiretroviral therapy initiated within 6 months of HIV infection is associated with lower T-cell activation and smaller HIV reservoir size.
The Journal of infectious diseases 2013 Jain V, Hartogensis W, Bacchetti P, Hunt PW, Hatano H, Sinclair E, Epling L, Lee TH, Busch MP, McCune JM, Pilcher CD, Hecht FM, Deeks SG -
Incidence and timing of cancer in HIV-infected individuals following initiation of combination antiretroviral therapy.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2013 Yanik EL, Napravnik S, Cole SR, Achenbach CJ, Gopal S, Olshan A, Dittmer DP, Kitahata MM, Mugavero MJ, Saag M, Moore RD, Mayer K, Mathews WC, Hunt PW, Rodriguez B, Eron JJ -
A simple LC-MS/MS method for determination of kynurenine and tryptophan concentrations in human plasma from HIV-infected patients.
Bioanalysis 2013 Huang Y, Louie A, Yang Q, Massenkoff N, Xu C, Hunt PW, Gee W -
GPS-measured distance to clinic, but not self-reported transportation factors, are associated with missed HIV clinic visits in rural Uganda.
AIDS (London, England) 2013 Siedner MJ, Lankowski A, Tsai AC, Muzoora C, Martin JN, Hunt PW, Haberer JE, Bangsberg DR -
Hematologic, hepatic, renal, and lipid laboratory monitoring after initiation of combination antiretroviral therapy in the United States, 2000-2010.
Journal of acquired immune deficiency syndromes (1999) 2013 Yanik EL, Napravnik S, Ryscavage P, Eron JJ, Koletar SL, Moore RD, Zinski A, Cole SR, Hunt P, Crane HM, Kahn J, Mathews WC, Mayer KH, Taiwo BO, Center for Aids Research Network of Integrated Clinical … -
Incidence and predictors of pregnancy among a cohort of HIV-positive women initiating antiretroviral therapy in Mbarara, Uganda.
PloS one 2013 Kaida A, Matthews LT, Kanters S, Kabakyenga J, Muzoora C, Mocello AR, Martin JN, Hunt P, Haberer J, Hogg RS, Bangsberg DR -
CD8+ T-cell activation in HIV-1-infected patients experiencing transient low-level viremia during antiretroviral therapy.
Journal of acquired immune deficiency syndromes (1999) 2013 Taiwo B, Hunt PW, Gandhi RT, Ellingson A, McKenna M, Jacobson JM, Gripshover B, Bosch RJ -
Dissemination of research findings to research participants living with HIV in rural Uganda: challenges and rewards.
PLoS medicine 2013 Baylor A, Muzoora C, Bwana M, Kembabazi A, Haberer JE, Matthews LT, Tsai AC, Hunt PW, Martin JN, Bangsberg DR -
Higher baseline CD4 cell count predicts treatment interruptions and persistent viremia in patients initiating ARVs in rural Uganda.
Journal of acquired immune deficiency syndromes (1999) 2013 Adakun SA, Siedner MJ, Muzoora C, Haberer JE, Tsai AC, Hunt PW, Martin JN, Bangsberg DR -
Immune Activation While on Potent Antiretroviral Therapy Can Predict Subsequent CD4+ T-Cell Increases Through 15 Years of Treatment.
HIV clinical trials 2013 Zhang X, Hunt PW, Hammer SM, Cespedes MS, Patterson KB, Bosch RJ -
Comparative analysis of measures of viral reservoirs in HIV-1 eradication studies.
PLoS pathogens 2013 Eriksson S, Graf EH, Dahl V, Strain MC, Yukl SA, Lysenko ES, Bosch RJ, Lai J, Chioma S, Emad F, Abdel-Mohsen M, Hoh R, Hecht F, Hunt P, Somsouk M, Wong J, Johnston R, Siliciano RF, Richman DD, O'… -
Effect of statin therapy in reducing the risk of serious non-AIDS-defining events and nonaccidental death.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2013 Overton ET, Kitch D, Benson CA, Hunt PW, Stein JH, Smurzynski M, Ribaudo HJ, Tebas P -
Evidence for the reliability and validity of the internalized AIDS-related stigma scale in rural Uganda.
AIDS and behavior 2013 Tsai AC, Weiser SD, Steward WT, Mukiibi NF, Kawuma A, Kembabazi A, Muzoora C, Hunt PW, Martin JN, Bangsberg DR -
No association found between traditional healer use and delayed antiretroviral initiation in rural Uganda.
AIDS and behavior 2013 Horwitz RH, Tsai AC, Maling S, Bajunirwe F, Haberer JE, Emenyonu N, Muzoora C, Hunt PW, Martin JN, Bangsberg DR -
Residual immune dysregulation syndrome in treated HIV infection.
Advances in immunology 2013 Lederman MM, Funderburg NT, Sekaly RP, Klatt NR, Hunt PW -
Sexual relationship power and depression among HIV-infected women in Rural Uganda.
PloS one 2012 Hatcher AM, Tsai AC, Kumbakumba E, Dworkin SL, Hunt PW, Martin JN, Clark G, Bangsberg DR, Weiser SD -
Activation, exhaustion, and persistent decline of the antimicrobial MR1-restricted MAIT-cell population in chronic HIV-1 infection.
Blood 2012 Leeansyah E, Ganesh A, Quigley MF, Sönnerborg A, Andersson J, Hunt PW, Somsouk M, Deeks SG, Martin JN, Moll M, Shacklett BL, Sandberg JK -
Lack of evidence for mtDNA as a biomarker of innate immune activation in HIV infection.
PloS one 2012 Lauring AS, Lee TH, Martin JN, Hunt PW, Deeks SG, Busch M -
Cell-based measures of viral persistence are associated with immune activation and programmed cell death protein 1 (PD-1)-expressing CD4+ T cells.
The Journal of infectious diseases 2012 Hatano H, Jain V, Hunt PW, Lee TH, Sinclair E, Do TD, Hoh R, Martin JN, McCune JM, Hecht F, Busch MP, Deeks SG -
Short communication: HIV+ viremic slow progressors maintain low regulatory T cell numbers in rectal mucosa but exhibit high T cell activation.
AIDS research and human retroviruses 2012 Shaw JM, Hunt PW, Critchfield JW, McConnell DH, Garcia JC, Pollard RB, Somsouk M, Deeks SG, Shacklett BL -
Changes in food insecurity, nutritional status, and physical health status after antiretroviral therapy initiation in rural Uganda.
Journal of acquired immune deficiency syndromes (1999) 2012 Weiser SD, Gupta R, Tsai AC, Frongillo EA, Grede N, Kumbakumba E, Kawuma A, Hunt PW, Martin JN, Bangsberg DR -
Optimizing network connectivity for mobile health technologies in sub-Saharan Africa.
PloS one 2012 Siedner MJ, Lankowski A, Musinga D, Jackson J, Muzoora C, Hunt PW, Martin JN, Bangsberg DR, Haberer JE -
Leaky gut, clotting, and vasculopathy in SIV.
Blood 2012 Hunt PW -
Sexual relationship power and malnutrition among HIV-positive women in rural Uganda.
AIDS and behavior 2012 Siedner MJ, Tsai AC, Dworkin S, Mukiibi NF, Emenyonu NI, Hunt PW, Haberer JE, Martin JN, Bangsberg DR, Weiser SD -
Immunologic basis of cardiovascular disease in HIV-infected adults.
The Journal of infectious diseases 2012 Hsue PY, Deeks SG, Hunt PW -
Carotid Intima-Media Thickness Progression in HIV-Infected Adults Occurs Preferentially at the Carotid Bifurcation and Is Predicted by Inflammation.
Journal of the American Heart Association 2012 Hsue PY, Scherzer R, Hunt PW, Schnell A, Bolger AF, Kalapus SC, Maka K, Martin JN, Ganz P, Deeks SG -
Cytomegalovirus immunoglobulin G antibody is associated with subclinical carotid artery disease among HIV-infected women.
The Journal of infectious diseases 2012 Parrinello CM, Sinclair E, Landay AL, Lurain N, Sharrett AR, Gange SJ, Xue X, Hunt PW, Deeks SG, Hodis HN, Kaplan RC -
CD28-negative CD4+ and CD8+ T cells in antiretroviral therapy-naive HIV-infected adults enrolled in adult clinical trials group studies.
The Journal of infectious diseases 2012 Tassiopoulos K, Landay A, Collier AC, Connick E, Deeks SG, Hunt P, Lewis DE, Wilson C, Bosch R -
Food insecurity, depression and the modifying role of social support among people living with HIV/AIDS in rural Uganda.
Social science & medicine (1982) 2012 Tsai AC, Bangsberg DR, Frongillo EA, Hunt PW, Muzoora C, Martin JN, Weiser SD -
Food insecurity is associated with morbidity and patterns of healthcare utilization among HIV-infected individuals in a resource-poor setting.
AIDS (London, England) 2012 Weiser SD, Tsai AC, Gupta R, Frongillo EA, Kawuma A, Senkungu J, Hunt PW, Emenyonu NI, Mattson JE, Martin JN, Bangsberg DR -
Expansion of CD8+ T cells lacking Sema4D/CD100 during HIV-1 infection identifies a subset of T cells with decreased functional capacity.
Blood 2011 Eriksson EM, Milush JM, Ho EL, Batista MD, Holditch SJ, Keh CE, Norris PJ, Keating SM, Deeks SG, Hunt PW, Martin JN, Rosenberg MG, Hecht FM, Nixon DF -
Impact of CD8+ T-cell activation on CD4+ T-cell recovery and mortality in HIV-infected Ugandans initiating antiretroviral therapy.
AIDS (London, England) 2011 Hunt PW, Cao HL, Muzoora C, Ssewanyana I, Bennett J, Emenyonu N, Kembabazi A, Neilands TB, Bangsberg DR, Deeks SG, Martin JN -
Altered distribution of mucosal NK cells during HIV infection.
Mucosal immunology 2011 Sips M, Sciaranghella G, Diefenbach T, Dugast AS, Berger CT, Liu Q, Kwon D, Ghebremichael M, Estes JD, Carrington M, Martin JN, Deeks SG, Hunt PW, Alter G -
Trends in the clinical characteristics of HIV-infected patients initiating antiretroviral therapy in Kenya, Uganda and Tanzania between 2002 and 2009.
Journal of the International AIDS Society 2011 Geng EH, Hunt PW, Diero LO, Kimaiyo S, Somi GR, Okong P, Bangsberg DR, Bwana MB, Cohen CR, Otieno JA, Wabwire D, Elul B, Nash D, Easterbrook PJ, Braitstein P, Musick BS, Martin JN, Yiannoutsos CT, … -
Old age and anti-cytomegalovirus immunity are associated with altered T-cell reconstitution in HIV-1-infected patients.
AIDS (London, England) 2011 Appay V, Fastenackels S, Katlama C, Ait-Mohand H, Schneider L, Guihot A, Keller M, Grubeck-Loebenstein B, Simon A, Lambotte O, Hunt PW, Deeks SG, Costagliola D, Autran B, Sauce D -
The role of SNPs in the α-chain of the IL-7R gene in CD4+ T-cell recovery in HIV-infected African patients receiving suppressive cART.
Genes and immunity 2011 Rajasuriar R, Booth DR, Gouillou M, Spelman T, James I, Solomon A, Chua K, Stewart G, Deeks S, Bangsberg DR, Muzoora C, Cameron PU, Hunt P, Martin J, Lewin SR -
Increased frequency of regulatory T cells accompanies increased immune activation in rectal mucosae of HIV-positive noncontrollers.
Journal of virology 2011 Shaw JM, Hunt PW, Critchfield JW, McConnell DH, Garcia JC, Pollard RB, Somsouk M, Deeks SG, Shacklett BL -
Cytomegalovirus viraemia in the modern antiretroviral era(*).
HIV medicine 2011 Jacobson M, Lurain N, Hunt P -
Differential microRNA regulation of HLA-C expression and its association with HIV control.
Nature 2011 Kulkarni S, Savan R, Qi Y, Gao X, Yuki Y, Bass SE, Martin MP, Hunt P, Deeks SG, Telenti A, Pereyra F, Goldstein D, Wolinsky S, Walker B, Young HA, Carrington M -
A randomized, controlled trial of raltegravir intensification in antiretroviral-treated, HIV-infected patients with a suboptimal CD4+ T cell response.
The Journal of infectious diseases 2011 Hatano H, Hayes TL, Dahl V, Sinclair E, Lee TH, Hoh R, Lampiris H, Hunt PW, Palmer S, McCune JM, Martin JN, Busch MP, Shacklett BL, Deeks SG -
HIV disease progression despite suppression of viral replication is associated with exhaustion of lymphopoiesis.
Blood 2011 Sauce D, Larsen M, Fastenackels S, Pauchard M, Ait-Mohand H, Schneider L, Guihot A, Boufassa F, Zaunders J, Iguertsira M, Bailey M, Gorochov G, Duvivier C, Carcelain G, Kelleher AD, Simon A, Meyer L, … -
T cell activation predicts carotid artery stiffness among HIV-infected women.
Atherosclerosis 2011 Kaplan RC, Sinclair E, Landay AL, Lurain N, Sharrett AR, Gange SJ, Xue X, Parrinello CM, Hunt P, Deeks SG, Hodis HN -
Regional anthropometry changes in antiretroviral-naïve persons initiating a Zidovudine-containing regimen in Mbarara, Uganda.
AIDS research and human retroviruses 2011 Thompson V, Medard B, Taseera K, Chakera AJ, Andia I, Emenyonu N, Hunt PW, Martin J, Scherzer R, Weiser SD, Bangsberg DR, Tien PC -
A low T regulatory cell response may contribute to both viral control and generalized immune activation in HIV controllers.
PloS one 2011 Hunt PW, Landay AL, Sinclair E, Martinson JA, Hatano H, Emu B, Norris PJ, Busch MP, Martin JN, Brooks C, McCune JM, Deeks SG -
Association of vitamin D insufficiency with carotid intima-media thickness in HIV-infected persons.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2011 Choi AI, Lo JC, Mulligan K, Schnell A, Kalapus SC, Li Y, Hunt PW, Martin JN, Deeks SG, Hsue PY -
HIV-specific CD4+ T cells may contribute to viral persistence in HIV controllers.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2011 Hunt PW, Hatano H, Sinclair E, Lee TH, Busch MP, Martin JN, McCune JM, Deeks SG -
T cell activation and senescence predict subclinical carotid artery disease in HIV-infected women.
The Journal of infectious diseases 2011 Kaplan RC, Sinclair E, Landay AL, Lurain N, Sharrett AR, Gange SJ, Xue X, Hunt P, Karim R, Kern DM, Hodis HN, Deeks SG -
Real-time adherence monitoring for HIV antiretroviral therapy.
AIDS and behavior 2010 Haberer JE, Kahane J, Kigozi I, Emenyonu N, Hunt P, Martin J, Bangsberg DR -
The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.
Science (New York, N.Y.) 2010 International HIV Controllers Study, Pereyra F, Jia X, McLaren PJ, Telenti A, de Bakker PI, Walker BD, Ripke S, Brumme CJ, Pulit SL, Carrington M, Kadie CM, Carlson JM, Heckerman D, Graham RR, Plenge … -
Evidence of persistent low-level viremia in long-term HAART-suppressed, HIV-infected individuals.
AIDS (London, England) 2010 Hatano H, Delwart EL, Norris PJ, Lee TH, Neilands TB, Kelley CF, Hunt PW, Hoh R, Linnen JM, Martin JN, Busch MP, Deeks SG -
HIV controllers with HLA-DRB1*13 and HLA-DQB1*06 alleles have strong, polyfunctional mucosal CD4+ T-cell responses.
Journal of virology 2010 Ferre AL, Hunt PW, McConnell DH, Morris MM, Garcia JC, Pollard RB, Yee HF, Martin JN, Deeks SG, Shacklett BL -
Immunodominant HIV-specific CD8+ T-cell responses are common to blood and gastrointestinal mucosa, and Gag-specific responses dominate in rectal mucosa of HIV controllers.
Journal of virology 2010 Ferre AL, Lemongello D, Hunt PW, Morris MM, Garcia JC, Pollard RB, Yee HF, Martin JN, Deeks SG, Shacklett BL -
Cerebrospinal fluid in HIV-1 systemic viral controllers: absence of HIV-1 RNA and intrathecal inflammation.
AIDS (London, England) 2010 Probasco JC, Deeks SG, Lee E, Hoh R, Hunt PW, Liegler T, Price RW, Spudich SS -
Th17, gut, and HIV: therapeutic implications.
Current opinion in HIV and AIDS 2010 Hunt PW -
Correlating cellular and molecular signatures of mucosal immunity that distinguish HIV controllers from noncontrollers.
Blood 2010 Loke P, Favre D, Hunt PW, Leung JM, Kanwar B, Martin JN, Deeks SG, McCune JM -
Cytomegalovirus-specific T cells persist at very high levels during long-term antiretroviral treatment of HIV disease.
PloS one 2010 Naeger DM, Martin JN, Sinclair E, Hunt PW, Bangsberg DR, Hecht F, Hsue P, McCune JM, Deeks SG -
Infection with different hiv subtypes is associated with CD4 activation-associated dysfunction and apoptosis.
Journal of acquired immune deficiency syndromes (1999) 2009 Bousheri S, Burke C, Ssewanyana I, Harrigan R, Martin J, Hunt P, Bangsberg DR, Cao H -
Natural control of HIV-1 replication and long-term nonprogression: overlapping but distinct phenotypes.
The Journal of infectious diseases 2009 Hunt PW -
Impact of HIV infection on diastolic function and left ventricular mass.
Circulation. Heart failure 2009 Hsue PY, Hunt PW, Ho JE, Farah HH, Schnell A, Hoh R, Martin JN, Deeks SG, Bolger AF -
HIV-infected persons continue to lose kidney function despite successful antiretroviral therapy.
AIDS (London, England) 2009 Choi AI, Shlipak MG, Hunt PW, Martin JN, Deeks SG -
Association of abacavir and impaired endothelial function in treated and suppressed HIV-infected patients.
AIDS (London, England) 2009 Hsue PY, Hunt PW, Wu Y, Schnell A, Ho JE, Hatano H, Xie Y, Martin JN, Ganz P, Deeks SG -
Role of viral replication, antiretroviral therapy, and immunodeficiency in HIV-associated atherosclerosis.
AIDS (London, England) 2009 Hsue PY, Hunt PW, Schnell A, Kalapus SC, Hoh R, Ganz P, Martin JN, Deeks SG -
Human herpesvirus replication and abnormal CD8+ T cell activation and low CD4+ T cell counts in antiretroviral-suppressed HIV-infected patients.
PloS one 2009 Jacobson MA, Ditmer DP, Sinclair E, Martin JN, Deeks SG, Hunt P, Mocarski ES, Shiboski C -
Plasma levels of bacterial DNA correlate with immune activation and the magnitude of immune restoration in persons with antiretroviral-treated HIV infection.
The Journal of infectious diseases 2009 Jiang W, Lederman MM, Hunt P, Sieg SF, Haley K, Rodriguez B, Landay A, Martin J, Sinclair E, Asher AI, Deeks SG, Douek DC, Brenchley JM -
Incomplete peripheral CD4+ cell count restoration in HIV-infected patients receiving long-term antiretroviral treatment.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2009 Kelley CF, Kitchen CM, Hunt PW, Rodriguez B, Hecht FM, Kitahata M, Crane HM, Willig J, Mugavero M, Saag M, Martin JN, Deeks SG -
Mucosal immune responses to HIV-1 in elite controllers: a potential correlate of immune control.
Blood 2008 Ferre AL, Hunt PW, Critchfield JW, Young DH, Morris MM, Garcia JC, Pollard RB, Yee HF, Martin JN, Deeks SG, Shacklett BL -
Evidence for persistent low-level viremia in individuals who control human immunodeficiency virus in the absence of antiretroviral therapy.
Journal of virology 2008 Hatano H, Delwart EL, Norris PJ, Lee TH, Dunn-Williams J, Hunt PW, Hoh R, Stramer SL, Linnen JM, McCune JM, Martin JN, Busch MP, Deeks SG -
Host genetic determinants of HIV pathogenesis: an immunologic perspective.
Current opinion in HIV and AIDS 2008 Hunt PW, Carrington M -
Antiretroviral treatment effect on immune activation reduces cerebrospinal fluid HIV-1 infection.
Journal of acquired immune deficiency syndromes (1999) 2008 Sinclair E, Ronquillo R, Lollo N, Deeks SG, Hunt P, Yiannoutsos CT, Spudich S, Price RW -
Role of immune activation in HIV pathogenesis.
Current HIV/AIDS reports 2007 Hunt PW -
Interruption of enfuvirtide in HIV-1 infected adults with incomplete viral suppression on an enfuvirtide-based regimen.
The Journal of infectious diseases 2006 Deeks SG, Lu J, Hoh R, Neilands TB, Beatty G, Huang W, Liegler T, Hunt P, Martin JN, Kuritzkes DR -
Immune-based therapy for HIV infection: are acute and chronic HIV infection different diseases?
The Journal of infectious diseases 2006 Hunt PW, Deeks SG -
Rate of viral evolution and risk of losing future drug options in heavily pretreated, HIV-infected patients who continue to receive a stable, partially suppressive treatment regimen.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2006 Hatano H, Hunt P, Weidler J, Coakley E, Hoh R, Liegler T, Martin JN, Deeks SG -
Prevalence of CXCR4 tropism among antiretroviral-treated HIV-1-infected patients with detectable viremia.
The Journal of infectious diseases 2006 Hunt PW, Harrigan PR, Huang W, Bates M, Williamson DW, McCune JM, Price RW, Spudich SS, Lampiris H, Hoh R, Leigler T, Martin JN, Deeks SG -
Neutralizing antibody responses against autologous and heterologous viruses in acute versus chronic human immunodeficiency virus (HIV) infection: evidence for a constraint on the ability of HIV to completely evade neutralizing antibody responses.
Journal of virology 2006 Deeks SG, Schweighardt B, Wrin T, Galovich J, Hoh R, Sinclair E, Hunt P, McCune JM, Martin JN, Petropoulos CJ, Hecht FM -
The independent effect of drug resistance on T cell activation in HIV infection.
AIDS (London, England) 2006 Hunt PW, Deeks SG, Bangsberg DR, Moss A, Sinclair E, Liegler T, Bates M, Tsao G, Lampiris H, Hoh R, Martin JN -
A randomized pilot study comparing combination therapy plus enfuvirtide versus a treatment interruption followed by combination therapy plus enfuvirtide.
Antiviral therapy 2006 Beatty G, Hunt P, Smith A, Hoh R, Huang W, Martin J, Deeks SG -
Immunologic and virologic evolution during periods of intermittent and persistent low-level viremia.
AIDS (London, England) 2004 Karlsson AC, Younger SR, Martin JN, Grossman Z, Sinclair E, Hunt PW, Hagos E, Nixon DF, Deeks SG -
Immune activation set point during early HIV infection predicts subsequent CD4+ T-cell changes independent of viral load.
Blood 2004 Deeks SG, Kitchen CM, Liu L, Guo H, Gascon R, Narváez AB, Hunt P, Martin JN, Kahn JO, Levy J, McGrath MS, Hecht FM -
Continued CD4 cell count increases in HIV-infected adults experiencing 4 years of viral suppression on antiretroviral therapy.
AIDS (London, England) 2003 Hunt PW, Deeks SG, Rodriguez B, Valdez H, Shade SB, Abrams DI, Kitahata MM, Krone M, Neilands TB, Brand RJ, Lederman MM, Martin JN