Ryan Lokken, MD
Associate Professor
Radiology
School of Medicine

Lokken completed a one-year Interventional Radiology fellowship at UCSF in 2013. In 2013, he joined the University of Illinois Hospital Health & Science Center in Chicago as a radiologist specializing in vascular interventional radiology. In June 2018, he rejoined UCSF as an assistant professor of clinical radiology in the department’s Interventional Section.

Lokken is an associate editor for the Journal of Vascular and Interventional Radiology, the scientific journal of the Society for Interventional Radiology. His research focus is the investigation of clinical, genetic and immunological factors associated with outcomes of locoregional therapy for hepatocellular carcinoma and other malignancies.

• Optimal treatment for small HCC (<3 cm): Resection, liver transplantation, or locoregional therapy?
  JHEP reports : innovation in hepatology 2023 Wu X, Lokken RP, Mehta N
• Socioeconomic and Survival Analysis of Radioembolization in Patients with Intrahepatic Cholangiocarcinoma: A Propensity Score-Adjusted Study.
  Journal of vascular and interventional radiology : JVIR 2023 Wu X, Heller M, Lokken RP, Fidelman N, Lam A
• Influence of progestin-only hormonal use on hepatocellular adenomas: A retrospective cohort study.
  Contraception 2022 Qureshy Z, Lokken RP, Kakar S, Grab J, Mehta N, Sarkar M
• Clinical Outcomes and Patency after Transjugular Intrahepatic Portosystemic Shunt Reduction for Overshunting Adverse Events.
  Journal of vascular and interventional radiology : JVIR 2022 Shah RJ, Alqadi MM, Duvvuri M, Kim YJ, Tyagi R, Lokken RP, Gaba RC
• Pharmacokinetics and Early Tumor Response to Conventional Transarterial Chemoembolization with Sorafenib and Doxorubicin in a VX2 Rabbit Tumor Model.
  Journal of vascular and interventional radiology : JVIR 2022 Elkhadragy L, Khabbaz RC, Muchiri RN, Totura WM, Samuelson JP, Whiteley HE, van Breemen RB, Lokken RP, Gaba RC
• Large thrombosed portomesenteric venous aneurysm treated with pharmacomechanical thrombolysis combined with TIPS placement.
  CVIR endovascular 2022 Kohlbrenner R, Schwertner AB, Vogel AR, Conrad M, Lokken RP
• Nonoperative Management of Unstable Patients with Solid Organ Injury: An Incompletely Mapped Frontier.
  Journal of vascular and interventional radiology : JVIR 2021 Lokken RP, Conrad MB
• Accuracy of Disclosed Financial Relationships between Radiologists and Industry at the 2018 RSNA Annual Meeting.
  Radiology 2021 Speir EJ, Hills NK, Lokken RP
• Conventional versus drug-eluting embolic transarterial chemoembolization with doxorubicin: comparative drug delivery, pharmacokinetics, and treatment response in a rabbit VX2 tumor model.
  Drug delivery and translational research 2021 Gaba RC, Khabbaz RC, Muchiri RN, Morrison JD, Elkhadragy L, Totura WM, Samuelson JP, Whiteley HE, Deaton RL, Nguyen PL, Sverdlov M, Johnson JJ, van Breemen RB, Lokken RP
• Hepatic Toxicity After Selective Chemoembolization Is Associated With Decreased Survival Among Patients With Hepatocellular Carcinoma.
  AJR. American journal of roentgenology 2021 Lokken RP, Kerlan RK, Chung YC, Chen YF, Mehta NJ, Yao FY, Fidelman N
• Nonfibered Packing Coil Embolization of Pulmonary Artery Pseudoaneurysm Resulting in a Delayed Endobronchial Coil Migration.
  Journal of vascular and interventional radiology : JVIR 2021 Schwertner A, Kohlbrenner RM, Seeley EJ, Lokken RP
• Catheter-Directed Thrombolysis for Submassive Pulmonary Embolism in the Third Trimester of Pregnancy.
  JACC. Case reports 2020 Compadre AJ, Kohi M, Lokken RP, Blissett S, Harris IS, Lucero J, Rosenstein MG, Sobhani NC
• Embolization of Arterial-Portal Fistula to Treat Associated Hemobilia after Transjugular Liver Biopsy.
  Seminars in interventional radiology 2020 Losey AD, Lokken RP, Kolli KP, Kerlan RK, Taylor AG, Kohi MP
• Intermediate to Long-Term Clinical Outcomes of Percutaneous Cryoablation for Renal Masses.
  Journal of vascular and interventional radiology : JVIR 2020 Knox J, Kohlbrenner R, Kolli K, Fidelman N, Kohi MP, Lehrman E, Lokken RP, Zagoria R, Kerlan RK, LaBerge J, Taylor AG
• Esophagopulmonary fistula causing pulmonary arterial pseudoaneurysms and massive hemoptysis.
  Radiology case reports 2020 Kord A, James E, Herren J, Gaba RC, Lokken RP
• Overdilation of a 6-mm Self-Expanding Stent with a 10-mm Balloon-Expandable Stent Graft Preserves Failing Meso-Rex Bypass.
  Journal of vascular and interventional radiology : JVIR 2020 Koethe Y, Lokken RP, Lehrman ED, Kerlan RK, Roberts JP, Rhee SJ, Kohi MP, Kolli KP
• Histology of Hepatocellular Carcinoma: Association with Clinical Features, Radiological Findings, and Locoregional Therapy Outcomes.
  Journal of clinical imaging science 2019 Park BV, Gaba RC, Huang YH, Chen YF, Guzman G, Lokken RP
• Arterial-portal fistula treated with hepatic arterial embolization and portal venous aneurysm stent-graft exclusion complicated by type 2 endoleak.
  Radiology case reports 2019 Bremer WA, Lokken RP, Gaba RC, Bui JT
• Locoregional Therapy of Hepatocellular-Cholangiocarcinoma versus Hepatocellular Carcinoma: A Propensity Score-Matched Study.
  Journal of vascular and interventional radiology : JVIR 2019 Huang YH, Park BV, Chen YF, Gaba RC, Guzman G, Lokken RP
• Tissue plasminogen activator dose and pulmonary artery pressure reduction in catheter directed thrombolysis of submassive pulmonary embolism.
  PloS one 2019 Patel DC, Gaba RC, Liu L, Lokken RP
• Transhepatic Revision of Occluded Transjugular Intrahepatic Portosystemic Shunt Complicated by Endotipsitis.
  Seminars in interventional radiology 2019 Darrow AW, Gaba RC, Lokken RP
• Development and Angiographic Use of the Rabbit VX2 Model for Liver Cancer.
  Journal of visualized experiments : JoVE 2019 Khabbaz RC, Huang YH, Smith AA, Garcia KD, Lokken RP, Gaba RC
• Eight Years' Experience With a Radiology-Sponsored Medical Student Research Fellowship Program.
  Journal of the American College of Radiology : JACR 2018 Gaba RC, Lokken RP, Zwanziger J, Girotti JA, Ray CE, Kashima K
• Characterization of an Inducible Alcoholic Liver Fibrosis Model for Hepatocellular Carcinoma Investigation in a Transgenic Porcine Tumorigenic Platform.
  Journal of vascular and interventional radiology : JVIR 2018 Gaba RC, Mendoza-Elias N, Regan DP, Garcia KD, Lokken RP, Schwind RM, Eichner M, Thomas FM, Rund LA, Schook LB, Schachtschneider KM
• 90Y Radioembolization for Hepatic Malignancy in Patients with Previous Biliary Intervention: Multicenter Analysis of Hepatobiliary Infections.
  Radiology 2018 Devulapalli KK, Fidelman N, Soulen MC, Miller M, Johnson MS, Addo E, El-Haddad G, Nutting C, Morrison J, Farsad K, Lokken RP, Gaba RC, Fleming J, Brown DB, Kwan SW, Rose SC, Pennycooke KA, Liu DM, …
• Albumin-Bilirubin and Platelet-Albumin-Bilirubin Grades Do Not Predict Survival After Transjugular Intrahepatic Portosystemic Shunt Creation.
  Cardiovascular and interventional radiology 2018 Khabbaz RC, Lokken RP, Chen YF, Lipnik AJ, Bui JT, Ray CE, Gaba RC
• Gastric Varices Bleed at Lower Portosystemic Pressure Gradients than Esophageal Varices.
  Journal of vascular and interventional radiology : JVIR 2018 Morrison JD, Mendoza-Elias N, Lipnik AJ, Lokken RP, Bui JT, Ray CE, Gaba RC
• Liver Masses: What Physicians Need to Know About Ordering and Interpreting Liver Imaging.
  Current gastroenterology reports 2017 Sheybani A, Gaba RC, Lokken RP, Berggruen SM, Mar WA
• Albumin-Bilirubin and Platelet-Albumin-Bilirubin Grades Accurately Predict Overall Survival in High-Risk Patients Undergoing Conventional Transarterial Chemoembolization for Hepatocellular Carcinoma.
  Journal of vascular and interventional radiology : JVIR 2017 Hansmann J, Evers MJ, Bui JT, Lokken RP, Lipnik AJ, Gaba RC, Ray CE
• Quality Improvement Guidelines for Transarterial Chemoembolization and Embolization of Hepatic Malignancy.
  Journal of vascular and interventional radiology : JVIR 2017 Gaba RC, Lokken RP, Hickey RM, Lipnik AJ, Lewandowski RJ, Salem R, Brown DB, Walker TG, Silberzweig JE, Baerlocher MO, Echenique AM, Midia M, Mitchell JW, Padia SA, Ganguli S, Ward TJ, Weinstein JL, …
• Liver Track Embolization After Islet Cell Transplant: Comparison of Two Techniques.
  AJR. American journal of roentgenology 2017 Gaba RC, Kobayashi KR, Bui JT, Lokken RP, Lipnik AJ, Ray CE, Oberholzer J
• Does advanced chronic kidney disease impact transjugular intrahepatic portosystemic shunt efficacy and safety?
  Acta gastro-enterologica Belgica 2017 Lakhoo J, Gunasekaran SS, Lokken RP, Lipnik AJ, Ray CE, Bui JT, Gaba RC
• Liver Infarction after Drug-Eluting Embolic Transarterial Chemoembolization for Hepatocellular Carcinoma in the Setting of a Large Portosystemic Shunt.
  Seminars in interventional radiology 2016 Park BV, Gaba RC, Lokken RP
• Filter Eversion Technique for Removal of Option ELITE Inferior Vena Cava Filters.
  Journal of vascular and interventional radiology : JVIR 2016 Vyas AR, Bui JT, Ray CE, Lokken RP, Gaba RC
• Safety and Efficacy of Doxorubicin Drug-Eluting Embolic Chemoembolization of Hepatocellular Carcinoma Supplied by Extrahepatic Collateral Arteries.
  Journal of vascular and interventional radiology : JVIR 2016 Lokken RP, Fidelman N, Kolli KP, Kerlan RK
• Validity of Newborn Clinical Assessment to Determine Gestational Age in Bangladesh.
  Pediatrics 2016 Lee AC, Mullany LC, Ladhani K, Uddin J, Mitra D, Ahmed P, Christian P, Labrique A, DasGupta SK, Lokken RP, Quaiyum M, Baqui AH, Projahnmo Study Group
• Transjugular Intrahepatic Portosystemic Shunt Creation and Variceal Coil or Plug Embolization Ineffectively Attain Gastric Variceal Decompression or Occlusion: Results of a 26-Patient Retrospective Study.
  Journal of vascular and interventional radiology : JVIR 2016 Lakhoo J, Bui JT, Lokken RP, Ray CE, Gaba RC
• Advanced Stent Graft Treatment of Venous Stenosis Affecting Hemodialysis Vascular Access: Case Illustrations.
  Seminars in interventional radiology 2016 Patel D, Ray CE, Lokken RP, Bui JT, Lipnik AJ, Gaba RC
• Root Cause Analysis of Rebleeding Events following Transjugular Intrahepatic Portosystemic Shunt Creation for Variceal Hemorrhage.
  Journal of vascular and interventional radiology : JVIR 2015 Lakhoo J, Bui JT, Zivin SP, Lokken RP, Minocha J, Ray CE, Gaba RC
• Diagnostic yield of CT urography in the evaluation of young adults with hematuria.
  AJR. American journal of roentgenology 2012 Lokken RP, Sadow CA, Silverman SG
• Air pollution and risk of stroke: underestimation of effect due to misclassification of time of event onset.
  Epidemiology (Cambridge, Mass.) 2009 Lokken RP, Wellenius GA, Coull BA, Burger MR, Schlaug G, Suh HH, Mittleman MA
• Inflammatory nodules mimic applicator track seeding after percutaneous ablation of renal tumors.
  AJR. American journal of roentgenology 2007 Lokken RP, Gervais DA, Arellano RS, Tuncali K, Morrison PR, Tatli S, Mueller PR, Silverman SG
• Physical activity of moderate intensity and risk of type 2 diabetes: a systematic review.
  Diabetes care 2007 Jeon CY, Lokken RP, Hu FB, van Dam RM
• Assembly of the U1 snRNP involves interactions with the backbone of the terminal stem of U1 snRNA.
  RNA (New York, N.Y.) 2003 McConnell TS, Lokken RP, Steitz JA