Peder Larson, PhD
Professor
Radiology
School of Medicine

Dr. Larson's research program includes a range of imaging technology development targeting improved clinical outcomes, with projects on metabolic MRI, lung MRI, myelin imaging, PET/MRI, and radiation therapy planning:

Metabolic imaging methods using hyperpolarized carbon-13 MRI This technology uses non-toxic, non-ionizing contrast agents to provide unique metabolism information, and is currently in clinical trials. Our team develops data acquisition, image reconstruction, and data analysis methods for this technology for a broad range of collaborators and applications. We are also leading new patient studies of this technology in renal cancers and heart disease.

Lung MRI Conventional MRI performs very poorly in the lungs but our team has developed methods based on ultrashort echo time (UTE) MRI to provide high quality, high-resolution lung MRI. We are pursuing development of functional imaging biomarkers and translation onto clinical MRI scanners, with a focus on pediatric studies to reduce radiation dose compared to CT.

Myelin MRI Our team has pioneered a new MRI approach for direct imaging of myelin based on ultrashort echo time (UTE) MRI. Other MRI methods provide indirect myelin measurements based measurements on nearby water. We are continuing to develop this technique as a quantitative imaging method, and translating into studies evaluating myelination in disease.

PET/MRI Hybrid PET/MRI systems combine the functional information from PET tracers with the soft-tissue contrast from MRI. Our team is working on PET/MRI technology developments for motion management, quantitative imaging, and multi-modal data analysis with this modality.

Radiation Therapy PLanning Applications of MRI in radiotherapy have increased significantly over the past decade due to the high level of soft tissue provided, often allowing for better visualization of tumors and organs at risk versus computed tomography (CT). Our team is working to develop specialized MR techniques to accurately estimate parameters used for radiotherapy dose calculation as a critical step towards MRI-only treatment planning.

Dr. Larson is an active member of International Society for Magnetic Resonance in Medicine, the Institute for Electrical and Electronics Engineering, the UC Berkeley and UCSF Graduate Group in Bioengineering, the California Institute for Quantitative Biosciences, and the Bakar Computational Health Sciences Institute.

• Mixed Supervision of Histopathology Improves Prostate Cancer Classification from MRI.
  IEEE transactions on medical imaging 2024 Rajagopal A, Westphalen AC, Velarde N, Simko JP, Nguyen H, Hope TA, Larson PEZ, Magudia K
• 3D balanced SSFP UTE MRI for multiple contrasts whole brain imaging.
  Magnetic resonance in medicine 2024 Shen X, Caverzasi E, Yang Y, Liu X, Green A, Henry RG, Emir U, Larson PEZ
• Current methods for hyperpolarized [1-13C]pyruvate MRI human studies.
  Magnetic resonance in medicine 2024 Larson PEZ, Bernard JML, Bankson JA, Bøgh N, Bok RA, Chen AP, Cunningham CH, Gordon JW, Hövener JB, Laustsen C, Mayer D, McLean MA, Schilling F, Slater JB, Vanderheyden JL, von Morze C, Vigneron DB, …
• Scan-specific Self-supervised Bayesian Deep Non-linear Inversion for Undersampled MRI Reconstruction.
  IEEE transactions on medical imaging 2024 Leynes AP, Deveshwar N, Nagarajan SS, Larson PEZ
• Quantification of the in vivo brain ultrashort-T2* component in healthy volunteers.
  Magnetic resonance in medicine 2024 Deveshwar N, Yao J, Han M, Dwork N, Shen X, Ljungberg E, Caverzasi E, Cao P, Henry R, Green A, Larson PEZ
• Advanced Hyperpolarized 13C Metabolic Imaging Protocol for Patients with Gliomas: A Comprehensive Multimodal MRI Approach.
  Cancers 2024 Autry AW, Vaziri S, Gordon JW, Chen HY, Kim Y, Dang D, LaFontaine M, Noeske R, Bok R, Villanueva-Meyer JE, Clarke JL, Oberheim Bush NA, Chang SM, Xu D, Lupo JM, Larson PEZ, Vigneron DB, Li Y
• Hyperpolarized 13 C metabolic imaging of the human abdomen with spatiotemporal denoising.
  Magnetic resonance in medicine 2024 Nickles TM, Kim Y, Lee PM, Chen HY, Ohliger M, Bok RA, Wang ZJ, Larson PEZ, Vigneron DB, Gordon JW
• Regional quantification of cardiac metabolism with hyperpolarized [1-13C]-pyruvate CMR evaluated in an oral glucose challenge.
  Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 2023 Larson PEZ, Tang S, Liu X, Sinha A, Dwork N, Sivalokanathan S, Liu J, Bok R, Ordovas KG, Slater J, Gordon JW, Abraham MR
• Probing human heart TCA cycle metabolism and response to glucose load using hyperpolarized [2-13 C]pyruvate MRS.
  NMR in biomedicine 2023 Chen HY, Gordon JW, Dwork N, Chung BT, Riselli A, Sivalokanathan S, Bok RA, Slater JB, Vigneron DB, Abraham MR, Larson PEZ
• Hyperpolarized 13 C Metabolic MRI of Patients with Pancreatic Ductal Adenocarcinoma.
  Journal of magnetic resonance imaging : JMRI 2023 Gordon JW, Chen HY, Nickles T, Lee PM, Bok R, Ohliger MA, Okamoto K, Ko AH, Larson PEZ, Wang ZJ
• Dynamic T2* relaxometry of hyperpolarized [1-13 C]pyruvate MRI in the human brain and kidneys.
  Magnetic resonance in medicine 2023 Liu X, Cui D, Xu D, Bok R, Wang ZJ, Vigneron DB, Larson PEZ, Gordon JW
• Current Methods for Hyperpolarized [1-13C]pyruvate MRI Human Studies.
  ArXiv 2023 Larson PE, Bernard JM, Bankson JA, Bøgh N, Bok RA, Chen AP, Cunningham CH, Gordon J, Hövener JB, Laustsen C, Mayer D, McLean MA, Schilling F, Slater J, Vanderheyden JL, von Morze C, Vigneron DB, Xu D,…
• Clinically Translatable Hyperpolarized 13C Bicarbonate pH Imaging Method for Use in Prostate Cancer.
  ACS sensors 2023 Mu C, Liu X, Kim Y, Riselli A, Korenchan DE, Bok RA, Delos Santos R, Sriram R, Qin H, Nguyen H, Gordon JW, Slater J, Larson PEZ, Vigneron DB, Kurhanewicz J, Wilson DM, Flavell RR
• Pulmonary Ventilation Analysis Using 1H Ultra-Short Echo Time (UTE) Lung MRI: A Reproducibility Study.
  bioRxiv : the preprint server for biology 2023 Tan F, Zhu X, Chan M, Deveshwar N, Willmering MM, Lustig M, Larson PEZ
• Probing Human Heart TCA Cycle Metabolism and Response to Glucose Load using Hyperpolarized [2-13C]Pyruvate MR Spectroscopy.
  medRxiv : the preprint server for health sciences 2023 Chen HY, Gordon JW, Dwork N, Chung BT, Riselli A, Sivalokanathan S, Bok RA, Slater JB, Vigneron DB, Abraham MR, Larson PEZ
• Regional quantification of cardiac metabolism with hyperpolarized [1-13C]-pyruvate MRI evaluated in an oral glucose challenge.
  medRxiv : the preprint server for health sciences 2023 Larson PEZ, Tang S, Liu X, Sinha A, Dwork N, Sivalokanathan S, Liu J, Bok R, Ordovas KG, Slater J, Gordon JW, Abraham MR
• Investigating cerebral perfusion with high resolution hyperpolarized [1-13 C]pyruvate MRI.
  Magnetic resonance in medicine 2023 Hu JY, Vaziri S, Bøgh N, Kim Y, Autry AW, Bok RA, Li Y, Laustsen C, Xu D, Larson PEZ, Chang S, Vigneron DB, Gordon JW
• Hyperpolarized [2-13C]pyruvate MR molecular imaging with whole brain coverage.
  NeuroImage 2023 Chung BT, Kim Y, Gordon JW, Chen HY, Autry AW, Lee PM, Hu JY, Tan CT, Suszczynski C, Chang SM, Villanueva-Meyer JE, Bok RA, Larson PEZ, Xu D, Li Y, Vigneron DB
• Atlas-Based Adaptive Hadamard-Encoded MR Spectroscopic Imaging at 3T.
  Tomography (Ann Arbor, Mich.) 2023 Liu H, Autry AW, Larson PEZ, Xu D, Li Y
• Multi-parametric hyperpolarized 13C/1H imaging reveals Warburg-related metabolic dysfunction and associated regional heterogeneity in high-grade human gliomas.
  NeuroImage. Clinical 2023 Autry AW, Vaziri S, LaFontaine M, Gordon JW, Chen HY, Kim Y, Villanueva-Meyer JE, Molinaro A, Clarke JL, Oberheim Bush NA, Xu D, Lupo JM, Larson PEZ, Vigneron DB, Chang SM, Li Y
• A metabolite specific 3D stack-of-spirals bSSFP sequence for improved bicarbonate imaging in hyperpolarized [1-13C]Pyruvate MRI.
  Journal of magnetic resonance (San Diego, Calif. : 1997) 2023 Liu X, Tang S, Cui D, Bok RA, Chen HY, Gordon JW, Wang ZJ, Larson PEZ
• Evaluation of major depressive disorder using 7 Tesla phase sensitive neuroimaging before and after mindfulness-based cognitive therapy.
  Journal of affective disorders 2023 Jakary A, Lupo JM, Mackin S, Yin A, Murray D, Yang T, Mukherjee P, Larson P, Xu D, Eisendrath S, Luks T, Li Y
• Co-Clinical Imaging Metadata Information (CIMI) for Cancer Research to Promote Open Science, Standardization, and Reproducibility in Preclinical Imaging.
  Tomography (Ann Arbor, Mich.) 2023 Moore SM, Quirk JD, Lassiter AW, Laforest R, Ayers GD, Badea CT, Fedorov AY, Kinahan PE, Holbrook M, Larson PEZ, Sriram R, Chenevert TL, Malyarenko D, Kurhanewicz J, Houghton AM, Ross BD, Pickup S, …
• Motion-compensated low-rank reconstruction for simultaneous structural and functional UTE lung MRI.
  Magnetic resonance in medicine 2023 Tan F, Zhu X, Chan M, Zapala MA, Vasanawala SS, Ong F, Lustig M, Larson PEZ
• An Online Repository for Pre-Clinical Imaging Protocols (PIPs).
  Tomography (Ann Arbor, Mich.) 2023 Gammon ST, Cohen AS, Lehnert AL, Sullivan DC, Malyarenko D, Manning HC, Hormuth DA, Daldrup-Link HE, An H, Quirk JD, Shoghi K, Pagel MD, Kinahan PE, Miyaoka RS, Houghton AM, Lewis MT, Larson P, Sriram…
• Metabolite-Specific Echo Planar Imaging for Preclinical Studies with Hyperpolarized 13C-Pyruvate MRI.
  Tomography (Ann Arbor, Mich.) 2023 Sahin SI, Ji X, Agarwal S, Sinha A, Mali I, Gordon JW, Mattingly M, Subramaniam S, Kurhanewicz J, Larson PEZ, Sriram R
• Optimization in the space domain for density compensation with the nonuniform FFT.
  Magnetic resonance imaging 2023 Dwork N, O'Connor D, Johnson EMI, Baron CA, Gordon JW, Pauly JM, Larson PEZ
• Synthesizing Complex-Valued Multicoil MRI Data from Magnitude-Only Images.
  Bioengineering (Basel, Switzerland) 2023 Deveshwar N, Rajagopal A, Sahin S, Shimron E, Larson PEZ
• Federated Learning with Research Prototypes: Application to Multi-Center MRI-based Detection of Prostate Cancer with Diverse Histopathology.
  Academic radiology 2023 Rajagopal A, Redekop E, Kemisetti A, Kulkarni R, Raman S, Sarma K, Magudia K, Arnold CW, Larson PEZ
• Evaluation of Apparent Diffusion Coefficient Repeatability and Reproducibility for Preclinical MRIs Using Standardized Procedures and a Diffusion-Weighted Imaging Phantom.
  Tomography (Ann Arbor, Mich.) 2023 Malyarenko D, Amouzandeh G, Pickup S, Zhou R, Manning HC, Gammon ST, Shoghi KI, Quirk JD, Sriram R, Larson P, Lewis MT, Pautler RG, Kinahan PE, Muzi M, Chenevert TL
• Synthetic PET via Domain Translation of 3-D MRI.
  IEEE transactions on radiation and plasma medical sciences 2022 Rajagopal A, Natsuaki Y, Wangerin K, Hamdi M, An H, Sunderland JJ, Laforest R, Kinahan PE, Larson PEZ, Hope TA
• A 13C/31P surface coil to visualize metabolism and energetics in the rodent brain at 3 Tesla.
  Journal of magnetic resonance (San Diego, Calif. : 1997) 2022 Vaidya MV, Zhang B, Hong D, Brown R, Batsios G, Viswanath P, Paska J, Wulf G, Grant AK, Ronen SM, Larson PEZ
• Assessment of higher-order singular value decomposition denoising methods on dynamic hyperpolarized [1-13C]pyruvate MRI data from patients with glioma.
  NeuroImage. Clinical 2022 Vaziri S, Autry AW, Lafontaine M, Kim Y, Gordon JW, Chen HY, Hu JY, Lupo JM, Chang SM, Clarke JL, Villanueva-Meyer JE, Bush NAO, Xu D, Larson PEZ, Vigneron DB, Li Y
• Improving multiparametric MR-transrectal ultrasound guided fusion prostate biopsies with hyperpolarized 13 C pyruvate metabolic imaging: A technical development study.
  Magnetic resonance in medicine 2022 Chen HY, Bok RA, Cooperberg MR, Nguyen HG, Shinohara K, Westphalen AC, Wang ZJ, Ohliger MA, Gebrezgiabhier D, Carvajal L, Gordon JW, Larson PEZ, Aggarwal R, Kurhanewicz J, Vigneron DB
• Generation of synthetic megavoltage CT for MRI-only radiotherapy treatment planning using a 3D deep convolutional neural network.
  Medical physics 2022 Scholey JE, Rajagopal A, Vasquez EG, Sudhyadhom A, Larson PEZ
• Kinetic analysis of multi-resolution hyperpolarized 13 C human brain MRI to study cerebral metabolism.
  Magnetic resonance in medicine 2022 Hu JY, Kim Y, Autry AW, Frost MM, Bok RA, Villanueva-Meyer JE, Xu D, Li Y, Larson PEZ, Vigneron DB, Gordon JW
• Development of specialized magnetic resonance acquisition techniques for human hyperpolarized [13 C,15 N2 ]urea + [1-13 C]pyruvate simultaneous perfusion and metabolic imaging.
  Magnetic resonance in medicine 2022 Liu X, Tang S, Mu C, Qin H, Cui D, Lai YC, Riselli AM, Delos Santos R, Carvajal L, Gebrezgiabhier D, Bok RA, Chen HY, Flavell RR, Gordon JW, Vigneron DB, Kurhanewicz J, Larson PEZ
• Improved accuracy of relative electron density and proton stopping power ratio through CycleGAN machine learning.
  Physics in medicine and biology 2022 Scholey J, Vinas L, Kearney V, Yom S, Larson PEZ, Descovich M, Sudhyadhom A
• Whole-Abdomen Metabolic Imaging of Healthy Volunteers Using Hyperpolarized [1-13 C]pyruvate MRI.
  Journal of magnetic resonance imaging : JMRI 2022 Lee PM, Chen HY, Gordon JW, Wang ZJ, Bok R, Hashoian R, Kim Y, Liu X, Nickles T, Cheung K, Alas FL, Daniel H, Larson PEZ, von Morze C, Vigneron DB, Ohliger MA
• Initial Experience on Hyperpolarized [1-13C]Pyruvate MRI Multicenter Reproducibility-Are Multicenter Trials Feasible?
  Tomography (Ann Arbor, Mich.) 2022 Bøgh N, Gordon JW, Hansen ESS, Bok RA, Blicher JU, Hu JY, Larson PEZ, Vigneron DB, Laustsen C
• US lesion visibility predicts clinically significant upgrade of prostate cancer by systematic biopsy.
  Abdominal radiology (New York) 2022 Velarde N, Westphalen AC, Nguyen HG, Neuhaus J, Shinohara K, Simko JP, Larson PE, Magudia K
• Acquisition and quantification pipeline for in vivo hyperpolarized 13 C MR spectroscopy.
  Magnetic resonance in medicine 2021 Hong D, Batsios G, Viswanath P, Gillespie AM, Vaidya M, Larson PEZ, Ronen SM
• Hyperpolarized 1-[13C]-Pyruvate Magnetic Resonance Imaging Detects an Early Metabolic Response to Immune Checkpoint Inhibitor Therapy in Prostate Cancer.
  European urology 2021 de Kouchkovsky I, Chen HY, Ohliger MA, Wang ZJ, Bok RA, Gordon JW, Larson PEZ, Frost M, Okamoto K, Cooperberg MR, Kurhanewicz J, Vigneron DB, Aggarwal R
• Harmonization of PET image reconstruction parameters in simultaneous PET/MRI.
  EJNMMI physics 2021 Laforest R, Khalighi M, Natsuaki Y, Rajagopal A, Chandramohan D, Byrd D, An H, Larson P, James SS, Sunderland JJ, Kinahan PE, Hope TA
• Attenuation Coefficient Estimation for PET/MRI With Bayesian Deep Learning Pseudo-CT and Maximum-Likelihood Estimation of Activity and Attenuation.
  IEEE transactions on radiation and plasma medical sciences 2021 Leynes AP, Ahn S, Wangerin KA, Kaushik SS, Wiesinger F, Hope TA, Larson PEZ
• Evaluation of attenuation correction in PET/MRI with synthetic lesion insertion.
  Journal of medical imaging (Bellingham, Wash.) 2021 Hamdi M, Natsuaki Y, Wangerin KA, An H, St James S, Kinahan PE, Sunderland JJ, Larson PEZ, Hope TA, Laforest R
• Metabolic imaging detects elevated glucose flux through the pentose phosphate pathway associated with TERT expression in low-grade gliomas.
  Neuro-oncology 2021 Viswanath P, Batsios G, Ayyappan V, Taglang C, Gillespie AM, Larson PEZ, Luchman HA, Costello JF, Pieper RO, Ronen SM
• Clinical translation of hyperpolarized 13 C pyruvate and urea MRI for simultaneous metabolic and perfusion imaging.
  Magnetic resonance in medicine 2021 Qin H, Tang S, Riselli AM, Bok RA, Delos Santos R, van Criekinge M, Gordon JW, Aggarwal R, Chen R, Goddard G, Zhang CT, Chen A, Reed G, Ruscitto DM, Slater J, Sriram R, Larson PEZ, Vigneron DB, …
• Quantitative analysis of repaired rabbit supraspinatus tendons (± channeling) using magnetic resonance imaging at 7 Tesla.
  Quantitative Imaging in Medicine and Surgery 2021 Guy Trudel, Samuel Duchesne-Bélanger, Justin Thomas, Gerd Melkus, Greg O. Cron, Peder E. Z. Larson, Mark Schweitzer, Adnan Sheikh, Hakim Louati, Odette Laneuville
• A Path to Qualification of PET/MRI Scanners for Multicenter Brain Imaging Studies: Evaluation of MRI-Based Attenuation Correction Methods Using a Patient Phantom.
  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2021 Catana C, Laforest R, An H, Boada F, Cao T, Faul D, Jakoby B, Jansen FP, Kemp BJ, Kinahan PE, Larson P, Levine MA, Maniawski P, Mawlawi O, McConathy JE, McMillan AB, Price JC, Rajagopal A, Sunderland …
• Specialized computational methods for denoising, B1 correction, and kinetic modeling in hyperpolarized 13 C MR EPSI studies of liver tumors.
  Magnetic resonance in medicine 2021 Lee PM, Chen HY, Gordon JW, Zhu Z, Larson PEZ, Dwork N, Van Criekinge M, Carvajal L, Ohliger MA, Wang ZJ, Xu D, Kurhanewicz J, Bok RA, Aggarwal R, Munster PN, Vigneron DB
• Denoising of hyperpolarized 13 C MR images of the human brain using patch-based higher-order singular value decomposition.
  Magnetic resonance in medicine 2021 Kim Y, Chen HY, Autry AW, Villanueva-Meyer J, Chang SM, Li Y, Larson PEZ, Brender JR, Krishna MC, Xu D, Vigneron DB, Gordon JW
• Hyperpolarized Metabolic MRI-Acquisition, Reconstruction, and Analysis Methods.
  Metabolites 2021 Larson PEZ, Gordon JW
• Imaging 6-Phosphogluconolactonase Activity in Brain Tumors In Vivo Using Hyperpolarized δ-[1-13C]gluconolactone.
  Frontiers in oncology 2021 Batsios G, Taglang C, Cao P, Gillespie AM, Najac C, Subramani E, Wilson DM, Flavell RR, Larson PEZ, Ronen SM, Viswanath P
• Optimizing trajectory ordering for fast radial ultra-short TE (UTE) acquisitions.
  Journal of magnetic resonance (San Diego, Calif. : 1997) 2021 Zhu X, Tan F, Johnson K, Larson P
• Utilizing the Wavelet Transform's Structure in Compressed Sensing.
  Signal, image and video processing 2021 Dwork N, O'Connor D, Baron CA, Johnson EMI, Kerr AB, Pauly JM, Larson PEZ
• Di-chromatic interpolation of magnetic resonance metabolic images.
  Magma (New York, N.Y.) 2021 Dwork N, Gordon JW, Tang S, O'Connor D, Hansen ESS, Laustsen C, Larson PEZ
• Modeling hyperpolarized lactate signal dynamics in cells, patient-derived tissue slice cultures and murine models.
  NMR in biomedicine 2021 Ahamed F, Van Criekinge M, Wang ZJ, Kurhanewicz J, Larson P, Sriram R
• Non-invasive assessment of telomere maintenance mechanisms in brain tumors.
  Nature communications 2021 Viswanath P, Batsios G, Mukherjee J, Gillespie AM, Larson PEZ, Luchman HA, Phillips JJ, Costello JF, Pieper RO, Ronen SM
• Fast variable density Poisson-disc sample generation with directional variation for compressed sensing in MRI.
  Magnetic resonance imaging 2020 Dwork N, Baron CA, Johnson EMI, O'Connor D, Pauly JM, Larson PEZ
• Technical Note: A methodology for improved accuracy in stopping power estimation using MRI and CT.
  Medical physics 2020 Scholey JE, Chandramohan D, Naren T, Liu W, Larson PEZ, Sudhyadhom A
• 68Ga-PSMA-11 PET/MRI: determining ideal acquisition times to reduce noise and increase image quality.
  EJNMMI physics 2020 Murthy V, Smith RL, Tao DH, Lawhn-Heath CA, Korenchan DE, Larson PEZ, Flavell RR, Hope TA
• Slice profile effects on quantitative analysis of hyperpolarized pyruvate.
  NMR in biomedicine 2020 Walker CM, Gordon JW, Xu Z, Michel KA, Li L, Larson PEZ, Vigneron DB, Bankson JA
• 55 Mn-based fiducial markers for rapid and automated RF coil localization for hyperpolarized 13 C MRI.
  Magnetic resonance in medicine 2020 Ohliger MA, Gordon JW, Carvajal L, Larson PEZ, Ou JJ, Agarwal S, Zhu Z, Vigneron DB, von Morze C
• MR-based Attenuation Correction for Brain PET Using 3D Cycle-Consistent Adversarial Network.
  IEEE transactions on radiation and plasma medical sciences 2020 Gong K, Yang J, Larson PEZ, Behr SC, Hope TA, Seo Y, Li Q
• Characterization of serial hyperpolarized 13C metabolic imaging in patients with glioma.
  NeuroImage. Clinical 2020 Autry AW, Gordon JW, Chen HY, LaFontaine M, Bok R, Van Criekinge M, Slater JB, Carvajal L, Villanueva-Meyer JE, Chang SM, Clarke JL, Lupo JM, Xu D, Larson PEZ, Vigneron DB, Li Y
• 3D Magnetic Resonance Spirometry.
  Scientific reports 2020 Boucneau T, Fernandez B, Larson P, Darrasse L, Maître X
• Tensor image enhancement and optimal multichannel receiver combination analyses for human hyperpolarized 13 C MRSI.
  Magnetic resonance in medicine 2020 Chen HY, Autry AW, Brender JR, Kishimoto S, Krishna MC, Vareth M, Bok RA, Reed GD, Carvajal L, Gordon JW, van Criekinge M, Korenchan DE, Chen AP, Xu D, Li Y, Chang SM, Kurhanewicz J, Larson PEZ, …
• Simultaneous Metabolic and Perfusion Imaging Using Hyperpolarized 13C MRI Can Evaluate Early and Dose-Dependent Response to Radiation Therapy in a Prostate Cancer Mouse Model.
  International journal of radiation oncology, biology, physics 2020 Qin H, Zhang V, Bok RA, Santos RD, Cunha JA, Hsu IC, Santos Bs JD, Lee JE, Sukumar S, Larson PEZ, Vigneron DB, Wilson DM, Sriram R, Kurhanewicz J
• In vivo detection of γ-glutamyl-transferase up-regulation in glioma using hyperpolarized γ-glutamyl-[1-13C]glycine.
  Scientific reports 2020 Batsios G, Najac C, Cao P, Viswanath P, Subramani E, Saito Y, Gillespie AM, Yoshihara HAI, Larson P, Sando S, Ronen SM
• Extreme MRI: Large-scale volumetric dynamic imaging from continuous non-gated acquisitions.
  Magnetic resonance in medicine 2020 Ong F, Zhu X, Cheng JY, Johnson KM, Larson PEZ, Vasanawala SS, Lustig M
• Hyperpolarized 13 C MRI data acquisition and analysis in prostate and brain at University of California, San Francisco.
  NMR in biomedicine 2020 Crane JC, Gordon JW, Chen HY, Autry AW, Li Y, Olson MP, Kurhanewicz J, Vigneron DB, Larson PEZ, Xu D
• Bone material analogues for PET/MRI phantoms.
  Medical physics 2020 Chandramohan D, Cao P, Han M, An H, Sunderland JJ, Kinahan PE, Laforest R, Hope TA, Larson PEZ
• A metabolite-specific 3D stack-of-spiral bSSFP sequence for improved lactate imaging in hyperpolarized [1-13 C]pyruvate studies on a 3T clinical scanner.
  Magnetic resonance in medicine 2020 Tang S, Bok R, Qin H, Reed G, VanCriekinge M, Delos Santos R, Overall W, Santos J, Gordon J, Wang ZJ, Vigneron DB, Larson PEZ
• Fast Imaging for Hyperpolarized MR Metabolic Imaging.
  Journal of magnetic resonance imaging : JMRI 2020 Gordon JW, Chen HY, Dwork N, Tang S, Larson PEZ
• Simultaneous T1 and T2 mapping of hyperpolarized 13C compounds using the bSSFP sequence.
  Journal of magnetic resonance (San Diego, Calif. : 1997) 2020 Milshteyn E, Reed GD, Gordon JW, von Morze C, Cao P, Tang S, Leynes AP, Larson PEZ, Vigneron DB
• Hyperpolarized 13C-pyruvate MRI detects real-time metabolic flux in prostate cancer metastases to bone and liver: a clinical feasibility study.
  Prostate cancer and prostatic diseases 2019 Chen HY, Aggarwal R, Bok RA, Ohliger MA, Zhu Z, Lee P, Gordon JW, van Criekinge M, Carvajal L, Slater JB, Larson PEZ, Small EJ, Kurhanewicz J, Vigneron DB
• First hyperpolarized [2-13C]pyruvate MR studies of human brain metabolism.
  Journal of magnetic resonance (San Diego, Calif. : 1997) 2019 Chung BT, Chen HY, Gordon J, Mammoli D, Sriram R, Autry AW, Le Page LM, Chaumeil MM, Shin P, Slater J, Tan CT, Suszczynski C, Chang S, Li Y, Bok RA, Ronen SM, Larson PEZ, Kurhanewicz J, Vigneron DB
• Technical Note: Simultaneous segmentation and relaxometry for MRI through multitask learning.
  Medical physics 2019 Cao P, Liu J, Tang S, Leynes AP, Lupo JM, Xu D, Larson PEZ
• Kinetic Modeling of Hyperpolarized Carbon-13 Pyruvate Metabolism in the Human Brain.
  IEEE transactions on medical imaging 2019 Mammoli D, Gordon J, Autry A, Larson PEZ, Li Y, Chen HY, Chung B, Shin P, Van Criekinge M, Carvajal L, Slater JB, Bok R, Crane J, Xu D, Chang S, Vigneron DB
• Using bidirectional chemical exchange for improved hyperpolarized [13 C]bicarbonate pH imaging.
  Magnetic resonance in medicine 2019 Korenchan DE, Gordon JW, Subramaniam S, Sriram R, Baligand C, VanCriekinge M, Bok R, Vigneron DB, Wilson DM, Larson PEZ, Kurhanewicz J, Flavell RR
• Effects of excitation angle strategy on quantitative analysis of hyperpolarized pyruvate.
  Magnetic resonance in medicine 2019 Walker CM, Fuentes D, Larson PEZ, Kundra V, Vigneron DB, Bankson JA
• Coil combination methods for multi-channel hyperpolarized 13C imaging data from human studies.
  Journal of magnetic resonance (San Diego, Calif. : 1997) 2019 Zhu Z, Zhu X, Ohliger MA, Tang S, Cao P, Carvajal L, Autry AW, Li Y, Kurhanewicz J, Chang S, Aggarwal R, Munster P, Xu D, Larson PEZ, Vigneron DB, Gordon JW
• Pulse sequence considerations for quantification of pyruvate-to-lactate conversion kPL in hyperpolarized 13 C imaging.
  NMR in biomedicine 2019 Chen HY, Gordon JW, Bok RA, Cao P, von Morze C, van Criekinge M, Milshteyn E, Carvajal L, Hurd RE, Kurhanewicz J, Vigneron DB, Larson PEZ
• Translation of Carbon-13 EPI for hyperpolarized MR molecular imaging of prostate and brain cancer patients.
  Magnetic resonance in medicine 2018 Gordon JW, Chen HY, Autry A, Park I, Van Criekinge M, Mammoli D, Milshteyn E, Bok R, Xu D, Li Y, Aggarwal R, Chang S, Slater JB, Ferrone M, Nelson S, Kurhanewicz J, Larson PEZ, Vigneron DB
• Dynamic diffusion-weighted hyperpolarized 13 C imaging based on a slice-selective double spin echo sequence for measurements of cellular transport.
  Magnetic resonance in medicine 2018 Zhu X, Gordon JW, Bok RA, Kurhanewicz J, Larson PEZ
• Investigation of analysis methods for hyperpolarized 13C-pyruvate metabolic MRI in prostate cancer patients.
  NMR in biomedicine 2018 Larson PEZ, Chen HY, Gordon JW, Korn N, Maidens J, Arcak M, Tang S, Criekinge M, Carvajal L, Mammoli D, Bok R, Aggarwal R, Ferrone M, Slater JB, Nelson SJ, Kurhanewicz J, Vigneron DB
• A regional bolus tracking and real-time B1 calibration method for hyperpolarized 13 C MRI.
  Magnetic resonance in medicine 2018 Tang S, Milshteyn E, Reed G, Gordon J, Bok R, Zhu X, Zhu Z, Vigneron DB, Larson PEZ
• Developing an efficient phase-matched attenuation correction method for quiescent period PET in abdominal PET/MRI.
  Physics in medicine and biology 2018 Yang J, Liu J, Wiesinger F, Menini A, Zhu X, Hope TA, Seo Y, Larson PEZ
• Non-Invasive Assessment of Lactate Production and Compartmentalization in Renal Cell Carcinomas Using Hyperpolarized 13C Pyruvate MRI.
  Cancers 2018 Sriram R, Gordon J, Baligand C, Ahamed F, Delos Santos J, Qin H, Bok RA, Vigneron DB, Kurhanewicz J, Larson PEZ, Wang ZJ
• A comparison of coil combination strategies in 3D multi-channel MRSI reconstruction for patients with brain tumors.
  NMR in biomedicine 2018 Vareth M, Lupo J, Larson P, Nelson S
• Measuring Tumor Metabolism in Pediatric Diffuse Intrinsic Pontine Glioma Using Hyperpolarized Carbon-13 MR Metabolic Imaging.
  Contrast media & molecular imaging 2018 Autry AW, Hashizume R, James CD, Larson PEZ, Vigneron DB, Park I
• High-resolution echo-planar spectroscopic imaging at ultra-high field.
  NMR in biomedicine 2018 Coello E, Noeske R, Burns BL, Gordon JW, Jakary A, Menze B, Haase A, Larson PEZ, Li Y, Schulte RF
• Spatio-Temporally Constrained Reconstruction for Hyperpolarized Carbon-13 MRI Using Kinetic Models.
  IEEE transactions on medical imaging 2018 Maidens J, Gordon JW, Chen HY, Park I, Van Criekinge M, Milshteyn E, Bok R, Aggarwal R, Ferrone M, Slater JB, Kurhanewicz J, Vigneron DB, Arcak M, Larson PEZ
• Cartilage Endplate Thickness Variation Measured by Ultrashort Echo-Time MRI Is Associated With Adjacent Disc Degeneration.
  Spine 2018 Berg-Johansen B, Han M, Fields AJ, Liebenberg EC, Lim BJ, Larson PE, Gunduz-Demir C, Kazakia GJ, Krug R, Lotz JC
• Quantification of 89 Zr-Iron oxide nanoparticle biodistribution using PET-MR and ultrashort TE sequences.
  Journal of magnetic resonance imaging : JMRI 2018 Jordan CD, Han M, Kondapavulur S, Vera DB, Neumann KD, Moore T, Stillson C, Krug R, Behr S, Seo Y, VanBrocklin HF, Larson PEZ, Wilson M, Martin AJ, Hetts SW
• MRI gradient-echo phase contrast of the brain at ultra-short TE with off-resonance saturation.
  NeuroImage 2018 Wei H, Cao P, Bischof A, Henry RG, Larson PEZ, Liu C
• Technique development of 3D dynamic CS-EPSI for hyperpolarized 13 C pyruvate MR molecular imaging of human prostate cancer.
  Magnetic resonance in medicine 2018 Chen HY, Larson PEZ, Gordon JW, Bok RA, Ferrone M, van Criekinge M, Carvajal L, Cao P, Pauly JM, Kerr AB, Park I, Slater JB, Nelson SJ, Munster PN, Aggarwal R, Kurhanewicz J, Vigneron DB
• Using a local low rank plus sparse reconstruction to accelerate dynamic hyperpolarized 13C imaging using the bSSFP sequence.
  Journal of magnetic resonance (San Diego, Calif. : 1997) 2018 Milshteyn E, von Morze C, Reed GD, Shang H, Shin PJ, Larson PEZ, Vigneron DB
• Simultaneous auto-calibration and gradient delays estimation (SAGE) in non-Cartesian parallel MRI using low-rank constraints.
  Magnetic resonance in medicine 2018 Jiang W, Larson PEZ, Lustig M
• In vivo hyperpolarization transfer in a clinical MRI scanner.
  Magnetic resonance in medicine 2018 von Morze C, Reed GD, Larson PE, Mammoli D, Chen AP, Tropp J, Van Criekinge M, Ohliger MA, Kurhanewicz J, Vigneron DB, Merritt ME
• Zero TE-based pseudo-CT image conversion in the head and its application in PET/MR attenuation correction and MR-guided radiation therapy planning.
  Magnetic resonance in medicine 2018 Wiesinger F, Bylund M, Yang J, Kaushik S, Shanbhag D, Ahn S, Jonsson JH, Lundman JA, Hope T, Nyholm T, Larson P, Cozzini C
• High spatiotemporal resolution bSSFP imaging of hyperpolarized [1-13 C]pyruvate and [1-13 C]lactate with spectral suppression of alanine and pyruvate-hydrate.
  Magnetic resonance in medicine 2018 Milshteyn E, von Morze C, Gordon JW, Zhu Z, Larson PEZ, Vigneron DB
• 3D hyperpolarized C-13 EPI with calibrationless parallel imaging.
  Journal of magnetic resonance (San Diego, Calif. : 1997) 2018 Gordon JW, Hansen RB, Shin PJ, Feng Y, Vigneron DB, Larson PEZ
• Development of methods and feasibility of using hyperpolarized carbon-13 imaging data for evaluating brain metabolism in patient studies.
  Magnetic resonance in medicine 2018 Park I, Larson PEZ, Gordon JW, Carvajal L, Chen HY, Bok R, Van Criekinge M, Ferrone M, Slater JB, Xu D, Kurhanewicz J, Vigneron DB, Chang S, Nelson SJ
• 2018 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP):
  Synthetic CT Generation Using MRI with Deep Learning: How Does the Selection of Input Images Affect the Resulting Synthetic CT? 2018 Leynes AP, Larson PEZ
• PET/MRI: Where might it replace PET/CT?.
  Journal of Magnetic Resonance Imaging 2017 Eric C. Ehman, Geoffrey B. Johnson, Javier E. Villanueva-Meyer, Soonmee Cha, Andrew Palmera Leynes, Peder Eric Zufall Larson, Thomas A. Hope
• Shuffled magnetization-prepared multicontrast rapid gradient-echo imaging.
  Magnetic resonance in medicine 2017 Cao P, Zhu X, Tang S, Leynes A, Jakary A, Larson PEZ
• Reliable and Reproducible GABA Measurements Using Automated Spectral Prescription at Ultra-High Field.
  Frontiers in human neuroscience 2017 Li Y, Bian W, Larson P, Crane JC, Parvathaneni P, Nagarajan S, Nelson SJ
• Density-weighted concentric rings k-space trajectory for 1 H magnetic resonance spectroscopic imaging at 7 T.
  NMR in biomedicine 2017 Chiew M, Jiang W, Burns B, Larson P, Steel A, Jezzard P, Albert Thomas M, Emir UE
• Motion robust high resolution 3D free-breathing pulmonary MRI using dynamic 3D image self-navigator.
  Magnetic resonance in medicine 2017 Jiang W, Ong F, Johnson KM, Nagle SK, Hope TA, Lustig M, Larson PEZ
• Evaluation of Sinus/Edge-Corrected Zero-Echo-Time-Based Attenuation Correction in Brain PET/MRI.
  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2017 Yang J, Wiesinger F, Kaushik S, Shanbhag D, Hope TA, Larson PEZ, Seo Y
• Dicarboxylic acids as pH sensors for hyperpolarized 13C magnetic resonance spectroscopic imaging.
  The Analyst 2017 Korenchan DE, Taglang C, von Morze C, Blecha JE, Gordon JW, Sriram R, Larson PEZ, Vigneron DB, VanBrocklin HF, Kurhanewicz J, Wilson DM, Flavell RR
• Assessing Prostate Cancer Aggressiveness with Hyperpolarized Dual-Agent 3D Dynamic Imaging of Metabolism and Perfusion.
  Cancer research 2017 Chen HY, Larson PEZ, Bok RA, von Morze C, Sriram R, Delos Santos R, Delos Santos J, Gordon JW, Bahrami N, Ferrone M, Kurhanewicz J, Vigneron DB
• Diffusion-weighted imaging of hyperpolarized [13 C]urea in mouse liver.
  Journal of magnetic resonance imaging : JMRI 2017 Marco-Rius I, Gordon JW, Mattis AN, Bok R, Delos Santos R, Sukumar S, Larson PEZ, Vigneron DB, Ohliger MA
• PET/MRI: Where might it replace PET/CT?
  Journal of magnetic resonance imaging : JMRI 2017 Ehman EC, Johnson GB, Villanueva-Meyer JE, Cha S, Leynes AP, Larson PEZ, Hope TA
• Hybrid ZTE/Dixon MR-based attenuation correction for quantitative uptake estimation of pelvic lesions in PET/MRI.
  Medical physics 2017 Leynes AP, Yang J, Shanbhag DD, Kaushik SS, Seo Y, Hope TA, Wiesinger F, Larson PE
• Quantitative Evaluation of Atlas-based Attenuation Correction for Brain PET in an Integrated Time-of-Flight PET/MR Imaging System.
  Radiology 2017 Yang J, Jian Y, Jenkins N, Behr SC, Hope TA, Larson PEZ, Vigneron D, Seo Y
• Imaging of the rabbit supraspinatus enthesis at 7 Tesla: a 4-week time course after repair surgery and effect of channeling.
  Journal of magnetic resonance imaging : JMRI 2017 Trudel G, Melkus G, Cron GO, Louati H, Sheikh A, Larson PEZ, Schweitzer M, Lapner P, Uhthoff HK, Laneuville O
• Development of high resolution 3D hyperpolarized carbon-13 MR molecular imaging techniques.
  Magnetic resonance imaging 2017 Milshteyn E, von Morze C, Reed GD, Shang H, Shin PJ, Zhu Z, Chen HY, Bok R, Goga A, Kurhanewicz J, Larson PE, Vigneron DB
• Monitoring acute metabolic changes in the liver and kidneys induced by fructose and glucose using hyperpolarized [2-13 C]dihydroxyacetone.
  Magnetic resonance in medicine 2016 Marco-Rius I, von Morze C, Sriram R, Cao P, Chang GY, Milshteyn E, Bok RA, Ohliger MA, Pearce D, Kurhanewicz J, Larson PE, Vigneron DB, Merritt M
• Spectrally selective three-dimensional dynamic balanced steady-state free precession for hyperpolarized C-13 metabolic imaging with spectrally selective radiofrequency pulses.
  Magnetic resonance in medicine 2016 Shang H, Sukumar S, von Morze C, Bok RA, Marco-Rius I, Kerr A, Reed GD, Milshteyn E, Ohliger MA, Kurhanewicz J, Larson PEZ, Pauly JM, Vigneron DB
• Mis-estimation and bias of hyperpolarized apparent diffusion coefficient measurements due to slice profile effects.
  Magnetic resonance in medicine 2016 Gordon JW, Milshteyn E, Marco-Rius I, Ohliger M, Vigneron DB, Larson PEZ
• Separation of extra- and intracellular metabolites using hyperpolarized (13)C diffusion weighted MR.
  Journal of magnetic resonance (San Diego, Calif. : 1997) 2016 Koelsch BL, Sriram R, Keshari KR, Leon Swisher C, Van Criekinge M, Sukumar S, Vigneron DB, Wang ZJ, Larson PEZ, Kurhanewicz J
• Combining hyperpolarized 13 C MRI with a liver-specific gadolinium contrast agent for selective assessment of hepatocyte metabolism.
  Magnetic resonance in medicine 2016 Ohliger MA, von Morze C, Marco-Rius I, Gordon J, Larson PEZ, Bok R, Chen HY, Kurhanewicz J, Vigneron D
• Imaging Renal Urea Handling in Rats at Millimeter Resolution using Hyperpolarized Magnetic Resonance Relaxometry.
  Tomography (Ann Arbor, Mich.) 2016 Reed GD, von Morze C, Verkman AS, Koelsch BL, Chaumeil MM, Lustig M, Ronen SM, Bok RA, Sands JM, Larson PE, Wang ZJ, Larsen JH, Kurhanewicz J, Vigneron DB
• Optimizing Flip Angles for Metabolic Rate Estimation in Hyperpolarized Carbon-13 MRI.
  IEEE transactions on medical imaging 2016 Maidens J, Gordon JW, Arcak M, Larson PE
• Accelerated high-bandwidth MR spectroscopic imaging using compressed sensing.
  Magnetic resonance in medicine 2016 Cao P, Shin PJ, Park I, Najac C, Marco-Rius I, Vigneron DB, Nelson SJ, Ronen SM, Larson PE
• Detection of localized changes in the metabolism of hyperpolarized gluconeogenic precursors 13 C-lactate and 13 C-pyruvate in kidney and liver.
  Magnetic resonance in medicine 2016 von Morze C, Chang GY, Larson PE, Shang H, Allu PK, Bok RA, Crane JC, Olson MP, Tan CT, Marco-Rius I, Nelson SJ, Kurhanewicz J, Pearce D, Vigneron DB
• Detecting Metabolism of Gluconeogenic Precursors Lactate and Pyruvate in Kidney & Liver with Hyperpolarized 13 C MRI.
  The FASEB Journal 2016 Cornelius von Morze, Gene-Yuan Chang, Peder E Larson, Hong Shang, Prasanna KR Allu, Robert A Bok, Jason C Crane, Marram P Olson, Chou T Tan, Irene Marco-Rius, Sarah J Nelson, John Kurhanewicz, David …
• Multiband spectral-spatial RF excitation for hyperpolarized [2-13 C]dihydroxyacetone 13 C-MR metabolism studies.
  Magnetic resonance in medicine 2016 Marco-Rius I, Cao P, von Morze C, Merritt M, Moreno KX, Chang GY, Ohliger MA, Pearce D, Kurhanewicz J, Larson PE, Vigneron DB
• Development of a symmetric echo planar imaging framework for clinical translation of rapid dynamic hyperpolarized 13 C imaging.
  Magnetic resonance in medicine 2016 Gordon JW, Vigneron DB, Larson PE
• Ultrashort echo time and zero echo time MRI at 7T.
  Magma (New York, N.Y.) 2015 Larson PE, Han M, Krug R, Jakary A, Nelson SJ, Vigneron DB, Henry RG, McKinnon G, Kelley DA
• Multiband RF pulses with improved performance via convex optimization.
  Journal of magnetic resonance (San Diego, Calif. : 1997) 2015 Shang H, Larson PEZ, Kerr A, Reed G, Sukumar S, Elkhaled A, Gordon JW, Ohliger MA, Pauly JM, Lustig M, Vigneron DB
• 1 H-13 C independently tuned radiofrequency surface coil applied for in vivo hyperpolarized MRI.
  Magnetic resonance in medicine 2015 Cao P, Zhang X, Park I, Najac C, Nelson SJ, Ronen S, Larson PE
• Development and testing of hyperpolarized (13)C MR calibrationless parallel imaging.
  Journal of magnetic resonance (San Diego, Calif. : 1997) 2015 Feng Y, Gordon JW, Shin PJ, von Morze C, Lustig M, Larson PEZ, Ohliger MA, Carvajal L, Tropp J, Pauly JM, Vigneron DB
• Dynamic contrast-enhanced quantitative susceptibility mapping with ultrashort echo time MRI for evaluating renal function.
  American journal of physiology. Renal physiology 2015 Xie L, Layton AT, Wang N, Larson PE, Zhang JL, Lee VS, Liu C, Johnson GA
• Application of Good's buffers to pH imaging using hyperpolarized (13)C MRI.
  Chemical communications (Cambridge, England) 2015 Flavell RR, von Morze C, Blecha JE, Korenchan DE, Van Criekinge M, Sriram R, Gordon JW, Chen HY, Subramaniam S, Bok RA, Wang ZJ, Vigneron DB, Larson PE, Kurhanewicz J, Wilson DM
• Quantifying temperature-dependent T1 changes in cortical bone using ultrashort echo-time MRI.
  Magnetic resonance in medicine 2015 Han M, Rieke V, Scott SJ, Ozhinsky E, Salgaonkar VA, Jones PD, Larson PE, Diederich CJ, Krug R
• Detection of Small Pulmonary Nodules with Ultrashort Echo Time Sequences in Oncology Patients by Using a PET/MR System.
  Radiology 2015 Burris NS, Johnson KM, Larson PE, Hope MD, Nagle SK, Behr SC, Hope TA
• Dynamic UltraFast 2D EXchange SpectroscopY (UF-EXSY) of hyperpolarized substrates.
  Journal of magnetic resonance (San Diego, Calif. : 1997) 2015 Leon Swisher C, Koelsch B, Sukumar S, Sriram R, Santos RD, Wang ZJ, Kurhanewicz J, Vigneron D, Larson P
• Handheld electromagnet carrier for transfer of hyperpolarized carbon-13 samples.
  Magnetic resonance in medicine 2015 Shang H, Skloss T, von Morze C, Carvajal L, Van Criekinge M, Milshteyn E, Larson PE, Hurd RE, Vigneron DB
• Concentric rings K-space trajectory for hyperpolarized (13)C MR spectroscopic imaging.
  Magnetic resonance in medicine 2014 Jiang W, Lustig M, Larson PE
• Simultaneous imaging of radiation-induced cerebral microbleeds, arteries and veins, using a multiple gradient echo sequence at 7 Tesla.
  Journal of magnetic resonance imaging : JMRI 2014 Bian W, Banerjee S, Kelly DA, Hess CP, Larson PE, Chang SM, Nelson SJ, Lupo JM
• Chemical shift separation with controlled aliasing for hyperpolarized (13) C metabolic imaging.
  Magnetic resonance in medicine 2014 Shin PJ, Larson PE, Uecker M, Reed GD, Kerr AB, Tropp J, Ohliger MA, Nelson SJ, Pauly JM, Lustig M, Vigneron DB
• Rapid in vivo apparent diffusion coefficient mapping of hyperpolarized (13) C metabolites.
  Magnetic resonance in medicine 2014 Koelsch BL, Reed GD, Keshari KR, Chaumeil MM, Bok R, Ronen SM, Vigneron DB, Kurhanewicz J, Larson PEZ
• Noninvasive in vivo imaging of diabetes-induced renal oxidative stress and response to therapy using hyperpolarized 13C dehydroascorbate magnetic resonance.
  Diabetes 2014 Keshari KR, Wilson DM, Sai V, Bok R, Jen KY, Larson P, Van Criekinge M, Kurhanewicz J, Wang ZJ
• Magnetic resonance imaging for lung cancer screen.
  Journal of thoracic disease 2014 Wang YX, Lo GG, Yuan J, Larson PE, Zhang X
• A 2DRF pulse sequence for bolus tracking in hyperpolarized 13C imaging.
  Magnetic resonance in medicine 2014 Tang S, Jiang W, Chen HY, Bok R, Vigneron DB, Larson PE
• Short-echo three-dimensional H-1 MR spectroscopic imaging of patients with glioma at 7 Tesla for characterization of differences in metabolite levels.
  Journal of magnetic resonance imaging : JMRI 2014 Li Y, Larson P, Chen AP, Lupo JM, Ozhinsky E, Kelley D, Chang SM, Nelson SJ
• Hyperpolarized [1-13C] glutamate: a metabolic imaging biomarker of IDH1 mutational status in glioma.
  Cancer research 2014 Chaumeil MM, Larson PE, Woods SM, Cai L, Eriksson P, Robinson AE, Lupo JM, Vigneron DB, Nelson SJ, Pieper RO, Phillips JJ, Ronen SM
• Depiction of achilles tendon microstructure in vivo using high-resolution 3-dimensional ultrashort echo-time magnetic resonance imaging at 7 T.
  Investigative radiology 2014 Han M, Larson PE, Liu J, Krug R
• Kinetic and perfusion modeling of hyperpolarized (13)C pyruvate and urea in cancer with arbitrary RF flip angles.
  Quantitative imaging in medicine and surgery 2014 Bahrami N, Swisher CL, Von Morze C, Vigneron DB, Larson PE
• Calibrationless parallel imaging reconstruction based on structured low-rank matrix completion.
  Magnetic resonance in medicine 2013 Shin PJ, Larson PE, Ohliger MA, Elad M, Pauly JM, Vigneron DB, Lustig M
• Dynamic hyperpolarized carbon-13 MR metabolic imaging of nonhuman primate brain.
  Magnetic resonance in medicine 2013 Park I, Larson PE, Tropp JL, Carvajal L, Reed G, Bok R, Robb F, Bringas J, Kells A, Pivirotto P, Bankiewicz K, Vigneron DB, Nelson SJ
• High resolution (13)C MRI with hyperpolarized urea: in vivo T(2) mapping and (15)N labeling effects.
  IEEE transactions on medical imaging 2013 Reed GD, von Morze C, Bok R, Koelsch BL, Van Criekinge M, Smith KJ, Larson PE, Kurhanewicz J, Vigneron DB
• Metabolic imaging of patients with prostate cancer using hyperpolarized [1-¹³C]pyruvate.
  Science translational medicine 2013 Nelson SJ, Kurhanewicz J, Vigneron DB, Larson PE, Harzstark AL, Ferrone M, van Criekinge M, Chang JW, Bok R, Park I, Reed G, Carvajal L, Small EJ, Munster P, Weinberg VK, Ardenkjaer-Larsen JH, Chen AP…
• Optimal variable flip angle schemes for dynamic acquisition of exchanging hyperpolarized substrates.
  Journal of magnetic resonance (San Diego, Calif. : 1997) 2013 Xing Y, Reed GD, Pauly JM, Kerr AB, Larson PE
• Signal scaling improves the signal-to-noise ratio of measurements with segmented 2D-selective radiofrequency excitations.
  Magnetic resonance in medicine 2013 Finsterbusch J, Busch MG, Larson PE
• Diffusion MR of hyperpolarized 13C molecules in solution.
  The Analyst 2013 Koelsch BL, Keshari KR, Peeters TH, Larson PE, Wilson DM, Kurhanewicz J
• Quantitative measurement of cancer metabolism using stimulated echo hyperpolarized carbon-13 MRS.
  Magnetic resonance in medicine 2013 Swisher CL, Larson PE, Kruttwig K, Kerr AB, Hu S, Bok RA, Goga A, Pauly JM, Nelson SJ, Kurhanewicz J, Vigneron DB
• Combined parallel and partial fourier MR reconstruction for accelerated 8-channel hyperpolarized carbon-13 in vivo magnetic resonance Spectroscopic imaging (MRSI).
  Journal of magnetic resonance imaging : JMRI 2013 Ohliger MA, Larson PE, Bok RA, Shin P, Hu S, Tropp J, Robb F, Carvajal L, Nelson SJ, Kurhanewicz J, Vigneron DB
• Non-invasive in vivo assessment of IDH1 mutational status in glioma.
  Nature communications 2013 Chaumeil MM, Larson PE, Yoshihara HA, Danforth OM, Vigneron DB, Nelson SJ, Pieper RO, Phillips JJ, Ronen SM
• Perfusion and diffusion sensitive 13C stimulated-echo MRSI for metabolic imaging of cancer.
  Magnetic resonance imaging 2012 Larson PE, Hurd RE, Kerr AB, Pauly JM, Bok RA, Kurhanewicz J, Vigneron DB
• Rapid sequential injections of hyperpolarized [1-¹³C]pyruvate in vivo using a sub-kelvin, multi-sample DNP polarizer.
  Magnetic resonance imaging 2012 Hu S, Larson PE, Vancriekinge M, Leach AM, Park I, Leon C, Zhou J, Shin PJ, Reed G, Keselman P, von Morze C, Yoshihara H, Bok RA, Nelson SJ, Kurhanewicz J, Vigneron DB
• A rapid method for direct detection of metabolic conversion and magnetization exchange with application to hyperpolarized substrates.
  Journal of magnetic resonance (San Diego, Calif. : 1997) 2012 Larson PE, Kerr AB, Swisher CL, Pauly JM, Vigneron DB
• Frequency-specific SSFP for hyperpolarized ¹³C metabolic imaging at 14.1 T.
  Magnetic resonance imaging 2012 von Morze C, Sukumar S, Reed GD, Larson PE, Bok RA, Kurhanewicz J, Vigneron DB
• A method for simultaneous echo planar imaging of hyperpolarized ¹³C pyruvate and ¹³C lactate.
  Journal of magnetic resonance (San Diego, Calif. : 1997) 2012 Reed GD, Larson PE, Morze Cv, Bok R, Lustig M, Kerr AB, Pauly JM, Kurhanewicz J, Vigneron DB
• Investigating tumor perfusion and metabolism using multiple hyperpolarized (13)C compounds: HP001, pyruvate and urea.
  Magnetic resonance imaging 2011 von Morze C, Larson PE, Hu S, Yoshihara HA, Bok RA, Goga A, Ardenkjaer-Larsen JH, Vigneron DB
• Hyperpolarized 13C dehydroascorbate as an endogenous redox sensor for in vivo metabolic imaging.
  Proceedings of the National Academy of Sciences of the United States of America 2011 Keshari KR, Kurhanewicz J, Bok R, Larson PE, Vigneron DB, Wilson DM
• Generating super stimulated-echoes in MRI and their application to hyperpolarized C-13 diffusion metabolic imaging.
  IEEE transactions on medical imaging 2011 Larson PE, Kerr AB, Reed GD, Hurd RE, Kurhanewicz J, Pauly JM, Vigneron DB
• In vivo measurement of normal rat intracellular pyruvate and lactate levels after injection of hyperpolarized [1-(13)C]alanine.
  Magnetic resonance imaging 2011 Hu S, Zhu M, Yoshihara HA, Wilson DM, Keshari KR, Shin P, Reed G, von Morze C, Bok R, Larson PE, Kurhanewicz J, Vigneron DB
• Ultrashort echo time MRI of cortical bone at 7 tesla field strength: a feasibility study.
  Journal of magnetic resonance imaging : JMRI 2011 Krug R, Larson PE, Wang C, Burghardt AJ, Kelley DA, Link TM, Zhang X, Vigneron DB, Majumdar S
• 13C-pyruvate imaging reveals alterations in glycolysis that precede c-Myc-induced tumor formation and regression.
  Cell metabolism 2011 Hu S, Balakrishnan A, Bok RA, Anderton B, Larson PE, Nelson SJ, Kurhanewicz J, Vigneron DB, Goga A
• Multi-band frequency encoding method for metabolic imaging with hyperpolarized [1-(13)C]pyruvate.
  Journal of magnetic resonance (San Diego, Calif. : 1997) 2011 von Morze C, Reed G, Shin P, Larson PE, Hu S, Bok R, Vigneron DB
• Science to practice: Can inflammatory arthritis be monitored by using MR imaging with injected hyperpolarized 13C-pyruvate?
  Radiology 2011 Larson PE, Gold GE
• Imaging of blood flow using hyperpolarized [(13)C]urea in preclinical cancer models.
  Journal of magnetic resonance imaging : JMRI 2011 von Morze C, Larson PE, Hu S, Keshari K, Wilson DM, Ardenkjaer-Larsen JH, Goga A, Bok R, Kurhanewicz J, Vigneron DB
• Multi-channel metabolic imaging, with SENSE reconstruction, of hyperpolarized [1-(13)C] pyruvate in a live rat at 3.0 tesla on a clinical MR scanner.
  Journal of magnetic resonance (San Diego, Calif. : 1997) 2010 Tropp J, Lupo JM, Chen A, Calderon P, McCune D, Grafendorfer T, Ozturk-Isik E, Larson PE, Hu S, Yen YF, Robb F, Bok R, Schulte R, Xu D, Hurd R, Vigneron D, Nelson S
• Fast dynamic 3D MR spectroscopic imaging with compressed sensing and multiband excitation pulses for hyperpolarized 13C studies.
  Magnetic resonance in medicine 2010 Larson PE, Hu S, Lustig M, Kerr AB, Nelson SJ, Kurhanewicz J, Pauly JM, Vigneron DB
• Hyperpolarized 13C spectroscopic imaging informs on hypoxia-inducible factor-1 and myc activity downstream of platelet-derived growth factor receptor.
  Cancer research 2010 Dafni H, Larson PE, Hu S, Yoshihara HA, Ward CS, Venkatesh HS, Wang C, Zhang X, Vigneron DB, Ronen SM
• Multi-compound polarization by DNP allows simultaneous assessment of multiple enzymatic activities in vivo.
  Journal of magnetic resonance (San Diego, Calif. : 1997) 2010 Wilson DM, Keshari KR, Larson PE, Chen AP, Hu S, Van Criekinge M, Bok R, Nelson SJ, Macdonald JM, Vigneron DB, Kurhanewicz J
• Investigation of tumor hyperpolarized [1-13C]-pyruvate dynamics using time-resolved multiband RF excitation echo-planar MRSI.
  Magnetic resonance in medicine 2010 Larson PE, Bok R, Kerr AB, Lustig M, Hu S, Chen AP, Nelson SJ, Pauly JM, Kurhanewicz J, Vigneron DB
• 3D compressed sensing for highly accelerated hyperpolarized (13)C MRSI with in vivo applications to transgenic mouse models of cancer.
  Magnetic resonance in medicine 2010 Hu S, Lustig M, Balakrishnan A, Larson PE, Bok R, Kurhanewicz J, Nelson SJ, Goga A, Pauly JM, Vigneron DB
• Hyperpolarized 13C magnetic resonance metabolic imaging: application to brain tumors.
  Neuro-oncology 2010 Park I, Larson PE, Zierhut ML, Hu S, Bok R, Ozawa T, Kurhanewicz J, Vigneron DB, Vandenberg SR, James CD, Nelson SJ
• Hyperpolarized [2-13C]-fructose: a hemiketal DNP substrate for in vivo metabolic imaging.
  Journal of the American Chemical Society 2009 Keshari KR, Wilson DM, Chen AP, Bok R, Larson PE, Hu S, Van Criekinge M, Macdonald JM, Vigneron DB, Kurhanewicz J
• Anisotropic field-of-view shapes for improved PROPELLER imaging.
  Magnetic resonance imaging 2008 Larson PE, Lustig MS, Nishimura DG
• Multiband excitation pulses for hyperpolarized 13C dynamic chemical-shift imaging.
  Journal of magnetic resonance (San Diego, Calif. : 1997) 2008 Larson PE, Kerr AB, Chen AP, Lustig MS, Zierhut ML, Hu S, Cunningham CH, Pauly JM, Kurhanewicz J, Vigneron DB
• IEEE Transactions on Medical Imaging
  Anisotropic Field-of-views in radial imaging 2008 Peder E. Z. Larson, Paul T. Gurney, and Dwight G. Nishimura
• Using adiabatic inversion pulses for long-T2 suppression in ultrashort echo time (UTE) imaging.
  Magnetic resonance in medicine 2007 Larson PE, Conolly SM, Pauly JM, Nishimura DG
• Montelukast dose selection in 6- to 14-year-olds: comparison of single-dose pharmacokinetics in children and adults.
  Journal of clinical pharmacology 1999 Knorr B, Larson P, Nguyen HH, Holland S, Reiss TF, Chervinsky P, Blake K, van Nispen CH, Noonan G, Freeman A, Haesen R, Michiels N, Rogers JD, Amin RD, Zhao J, Xu X, Seidenberg BC, Gertz BJ, Spielberg…