Pawan Kumar Raghav, PhD
Postdoctoral Scholar
Surgery
School of Medicine
Dr. Pawan Kumar Raghav completed his MSc in Bioinformatics (2008) from Punjabi University, Patiala, India; PG Diploma in Chemoinformatics (2009) from Jamia Hamdard; MPhil in Bioinformatics (2010) from The Global Open University, Nagaland; and Ph.D. at the Institute of Nuclear Medicine and Allied Sciences (INMAS), DRDO, Delhi in Life Sciences from Bharathiar University, Coimbatore.
Show full bio (290 words) Hide full bio
During his Ph.D., he designed molecules and evaluated their applications through response modification that regulates stem cells proliferation, differentiation, and apoptosis. His main research interest is in the field of drug designing against Cancer Stem Cells (CSCs). He has completed the Department of Science and Technology (DST), Government of India’s project as leading Principal Investigator (PI) in Department of Computational Biology, IIIT Delhi, India during his Post-Doc (2017-2019), awarded by DST, SERB. During this tenure, his research work included developing tools and databases using machine learning, deep learning algorithms, and new scoring function parameterizations for use in docking, simulations, and complex network analysis. Also, Dr. Pawan Kumar Raghav has worked as Scientist ‘D’ in Stem Cell Facility, AIIMS, New Delhi-110029, India. As a scientist, he carried out stem cell informatics, current Good Manufacturing Practices (cGMP), and tissue engineering experimental studies. Currently, he is working as a research scientist in Immunogenetics and Transplantation Lab, Department of Surgery, University of California San Francisco (UCSF), San Francisco, California. In UCSF, he is developing novel approaches for investigating immune/inflammatory mechanisms of allograft injury and discovering new biomarkers and therapeutics in solid organ and bone marrow transplantation. He is the recipient of several awards and honors, including the ICMR Travel Award to deliver an oral talk in 11th world congress & expo on cell & stem cell research ORLANDO, the USA in 2019, Research Excellence Award from Institute of Scholars (InSc), and best Research Award in 2020 from Science Father. He has published more than 40 publications, including international research articles, book chapters, books, and Indian intellectual property rights for 03 patents. His research activities and broad experience shows his significant contribution to stem cells engineering, nanotechnology, and computational biology.
Awards
Show all (11) Hide
- Reviewer, Human Immunology, ISSN: 0198-88590l, Elsevier, 2021
- Reviewer, SAGE Open Medical Case Reports, ISSN: 2050-313X, SAGE, 2021
- Reviewer, Pharmacological Reports, ISSN: 1734-1140, Springer, 2021
- Reviewer, Asian Journal of Research and Reports in Gastroenterology, AJRRG, 2020
- Reviewer, International Journal of Basic and Applied Sciences, ISSN: 2227-5053, InSc, 2020
- Research Excellence Award, Institute of Scholars (InSc), 2020
- Best Research Award, ScienceFather, 2020
- Reviewer Biochimie, ISSN: 0300-9084, Elsevier, 2019
- Travel Award, ICMR, 2019
- National Post-Doctoral Fellowship (N-PDF), SERB, DST, 2017-2019
- DRDO Research Fellowship, INMAS DRDO, 2011-2016
Education & Training
Show all (8) Hide
- Scientist D Stem Cells AIIMS 2020
- PostDoc Cancer Stem Cells IIIT 2019
- RA Stem Cells INMAS, DRDO 2017
- Ph.D Life Science Bharathiar University 2016
- M.Phil Bioinformatics The Global Open University 2010
- P.G. Diploma Chemoinformatics Jamia Hamdard 2009
- M.Sc. Bioinformatics Punjabi University Patiala 2008
- B.Sc. Zoology, Chemistry, Botany University of Delhi 2006
Interests
Show all (9) Hide
- Bioinformatics
- Cell Biology
- Nanotechnology
- Tissue Engineering
- Stem Cells
- Molecular Biology
- Machine Learning
- Drug Designing
- R programing
Websites
Show all (10) Hide
- Microsoft Academic (academic.microsoft.com)
- Publon (publons.com)
- Linkedin (linkedin.com)
- Research Gate (researchgate.net)
- Academia (rachet.academia.edu)
- Scopus (scopus.com)
- PubMed (pubmed.ncbi.nlm.nih.gov)
- Google Scholar (scholar.google.com)
- ORCID (orcid.org)
- Loop (loop.frontiersin.org)
Grants and Projects
Show all (1) Hide
- Role of Bcl-2 in Cancer Stem Cells and apoptosis pathway elucidation for development of novel molecules, DST SERB, 2019
Publications (28)
Top publication keywords:
MyelopoiesisProtein Tyrosine Phosphatase, Non-Receptor Type 11Stem Cell FactorProtein Tyrosine Phosphatase, Non-Receptor Type 6Proto-Oncogene Proteinsbcl-2-Associated X ProteinMegakaryocyte Progenitor CellsProto-Oncogene Proteins c-kitTissue ScaffoldsErythropoiesisErythroid CellsReceptors, VirusGATA1 Transcription FactorProto-Oncogene Proteins c-bcl-2Hematopoietic Stem Cells
-
PU.1 Mimic Synthetic Peptides Selectively Bind with GATA-1 and Allow c-Jun PU.1 Binding to Enhance Myelopoiesis.
International journal of nanomedicine 2021 Raghav PK, Gangenahalli G -
Cancer stem cells targets and combined therapies to prevent cancer recurrence.
Life sciences 2021 Raghav PK, Mann Z -
Docking-based approach for identification of mutations that disrupt binding between Bcl-2 and Bax proteins: Inducing apoptosis in cancer cells.
Molecular genetics & genomic medicine 2019 Raghav PK, Kumar R, Kumar V, Raghava GPS -
Stem cell factor and NSC87877 combine to enhance c-Kit mediated proliferation of human megakaryoblastic cells.
PloS one 2018 Raghav PK, Singh AK, Gangenahalli G -
Stem cell factor and NSC87877 synergism enhances c-Kit mediated proliferation of human erythroid cells.
Life sciences 2018 Raghav PK, Singh AK, Gangenahalli G -
A change in structural integrity of c-Kit mutant D816V causes constitutive signaling.
Mutation research 2018 Raghav PK, Singh AK, Gangenahalli G -
Peptide screening to knockdown Bcl-2's anti-apoptotic activity: implications in cancer treatment.
International journal of biological macromolecules 2011 Raghav PK, Verma YK, Gangenahalli GU -
Molecular dynamics simulations of the Bcl-2 protein to predict the structure of its unordered flexible loop domain.
Journal of molecular modeling 2011 Raghav PK, Verma YK, Gangenahalli GU
Show all (20 more) Hide
-
Potential treatments of COVID-19: Drug repurposing and therapeutic interventions
Journal of Pharmacological Sciences 2023 Pawan Kumar Raghav, Zoya Mann, Simran Kaur Ahluwalia, Raja Rajalingam -
Potential treatments of COVID-19: Drug repurposing and therapeutic interventions.
Journal of pharmacological sciences 2023 Raghav PK, Mann Z, Ahluwalia SK, Rajalingam R -
Experimental and clinical data analysis for identification of COVID-19 resistant ACE2 mutations
Scientific Reports, Springer Nature 2023 Pawan Kumar Raghav, Aditya Raghav, Anjali Lathwal, Archit Saxena, Zoya Mann, Manisha Sengar & Raja Rajalingam -
Hematopoietic Stem Cell Factors: Their Functional Role in Self-Renewal and Clinical Aspects.
Frontiers in cell and developmental biology 2022 Mann Z, Sengar M, Verma YK, Rajalingam R, Raghav PK -
Therapeutic Potential of Chemical Compounds in Targeting Cancer Stem Cells
Handbook of Oxidative Stress and Cancer: Therapeutic Aspect 2022 Pawan Kumar Raghav, Zoya Mann, Sujata Mohanty -
Mesenchymal stem cell-based nanoparticles and scaffolds in regenerative medicine.
European journal of pharmacology 2021 Raghav PK, Mann Z, Ahlawat S, Mohanty S -
Therapeutic effect of natural compounds in targeting ROS induced cancer
Handbook of Oxidative Stress in Cancer: Mechanistic Aspects 2021 Pawan Kumar Raghav, Zoya Mann, Vishnu Krishnakumar, Sujata Mohanty -
CoVAM: Complementary and Alternative Medicine Clinical Trials Database for COVID-19 Disease
Journal of Antivirals & Antiretrovirals 2021 Vishwas Sharma, Zoya Mann, Amitesh Sharma, Avani Srivastava, Pawan Kumar Raghav, Ritu Singh, Amrita Nandan -
Graphene nanofiber composites for enhanced neuronal differentiation of human mesenchymal stem cells.
Nanomedicine (London, England) 2021 Rawat S, Jain KG, Gupta D, Raghav PK, Chaudhuri R, Shakeel A, Arora V, Sharma H, Debnath D, Kalluri A, Agrawal AK, Jassal M, Dinda AK, Patra P, Mohanty S -
Nanomedicine
Graphene nanofiber composites for enhanced neuronal differentiation of human mesenchymal stem cells 2021 Sonali Rawat, Krishan Gopal Jain, Deepika Gupta, Pawan Kumar Raghav, Rituparna Chaudhuri, Pinky, Adeeba Shakeel, Varun Arora, Harshita Sharma, Debika Debnath, Ankarao Kalluri, Ashwini K. Agrawal, … -
Handbook of Oxidative Stress in Cancer: Mechanistic Aspects (Sajal Chakraborti, Bimal K Ray, Sushanta Roychowdhury)
Systems Biology Resources and Their Applications to Understand the Cancer 2021 Pawan Kumar Raghav, Zoya Mann, Pranav K. Pandey, and Sujata Mohanty -
Human cell receptors: potential drug targets to combat COVID-19.
Amino acids 2021 Raghav PK, Kalyanaraman K, Kumar D -
Synthetic peptide, nanoparticle formulation and implementation thereof
Synthetic peptide, nanoparticle formulation and implementation thereof 2020 Gurudutta Gangenahalli, Raghav Pawan Kumar -
Are graphene and graphene-derived products capable of preventing COVID-19 infection?
Medical hypotheses 2020 Kumar Raghav P, Mohanty S -
CancerEnD: A database of cancer associated enhancers.
Genomics 2020 Kumar R, Lathwal A, Kumar V, Patiyal S, Raghav PK, Raghava GPS -
ccPDB 2.0: an updated version of datasets created and compiled from Protein Data Bank.
Database : the journal of biological databases and curation 2019 Agrawal P, Patiyal S, Kumar R, Kumar V, Singh H, Raghav PK, Raghava GPS -
Correction: Stem cell factor and NSC87877 combine to enhance c-Kit mediated proliferation of human megakaryoblastic cells.
PloS one 2018 Raghav PK, Singh AK, Gangenahalli G -
Overview of Free Software Developed for Designing Drugs Based on Protein-Small Molecules Interaction.
Current topics in medicinal chemistry 2018 Agrawal P, Raghav PK, Bhalla S, Sharma N, Raghava GPS -
Stem cell fate and insight dependent design of molecules and their evaluation for gain-of therapeutic applications through response modification
Stem cell fate and insight dependent design of molecules and their evaluation for gain-of therapeutic applications through response modification 2016 Pawan Kumar Raghav -
Enhanced heterodimerization of Bax by Bcl-2 mutants improves irradiated cell survival.
Apoptosis : an international journal on programmed cell death 2013 Verma YK, Raghav PK, Raj HG, Tripathi RP, Gangenahalli GU