Paula Lum, MD, MPH
Professor
Medicine
School of Medicine

Her research and clinical activities are grounded in evidence-based, patient-centered care to improve the health and well-being of the urban poor. Her current areas of focus include: (1) HIV and viral hepatitis prevention and treatment in persons who use drugs, (2) evidence-based interventions in primary care and non-traditional settings for unhealthy substance use and its complications, and (3) curricular interventions to provide health care professionals with the skills, knowledge, and confidence to offer effective patient-centered care to persons who use drugs.

• A Video-Observed Treatment Strategy to Improve Adherence to Treatment Among Persons Who Inject Drugs Infected With Hepatitis C Virus: Qualitative Study of Stakeholder Perceptions and Experiences.
  Journal of medical Internet research 2023 Karasz A, Merchant K, Arnsten J, Feinberg J, Kim AY, Lum PJ, McKee MD, Mehta SH, Meissner P, Norton BL, Page K, Pericot-Valverde I, Singh R, Stein E, Taylor LE, Tsui JI, Wagner K, Litwin A
• Injecting practices during and after hepatitis C treatment and associations with not achieving cure among persons who inject drugs.
  Drug and alcohol dependence 2023 Tsui JI, Lum PJ, Taylor LE, Mehta SH, Feinberg J, Kim AY, Norton BL, Niu J, Heo M, Arnsten J, Pericot-Valverde I, Thomas A, Blalock KL, Radick A, Murray-Krezan C, Page K, Litwin AH, HERO Study Group
• Patient-centred models of hepatitis C treatment for people who inject drugs: a multicentre, pragmatic randomised trial.
  The lancet. Gastroenterology & hepatology 2022 Litwin AH, Lum PJ, Taylor LE, Mehta SH, Tsui JI, Feinberg J, Kim AY, Norton BL, Heo M, Arnsten J, Meissner P, Karasz A, Mckee MD, Ward JW, Johnson N, Pericot-Valverde I, Agyemang L, Stein ES, Thomas A…
• HIV clinic-based extended-release naltrexone versus treatment as usual for people with HIV and opioid use disorder: a non-blinded, randomized non-inferiority trial.
  Addiction (Abingdon, England) 2022 Korthuis PT, Cook RR, Lum PJ, Waddell EN, Tookes H, Vergara-Rodriguez P, Kunkel LE, Lucas GM, Rodriguez AE, Bielavitz S, Fanucchi LC, Hoffman KA, Bachrach K, Payne EH, Collins JA, Matthews A, Oden N, …
• Meeting people where they are: implementing hospital-based substance use harm reduction.
  Harm reduction journal 2022 Perera R, Stephan L, Appa A, Giuliano R, Hoffman R, Lum P, Martin M
• Perspectives on extended-release naltrexone induction among patients living with HIV and opioid use disorder: a qualitative analysis.
  Addiction science & clinical practice 2021 Hoffman KA, Baker R, Fanucchi LC, Lum PJ, Kunkel LE, Ponce Terashima J, McCarty D, Jacobs P, Korthuis PT
• Associations between fentanyl use and initiation, persistence, and retention on medications for opioid use disorder among people living with uncontrolled HIV disease.
  Drug and alcohol dependence 2021 Cook RR, Torralva R, King C, Lum PJ, Tookes H, Foot C, Vergara-Rodriguez P, Rodriguez A, Fanucchi L, Lucas GM, Waddell EN, Korthuis PT
• Randomized Trial of a Vaccine Regimen to Prevent Chronic HCV Infection.
  The New England journal of medicine 2021 Page K, Melia MT, Veenhuis RT, Winter M, Rousseau KE, Massaccesi G, Osburn WO, Forman M, Thomas E, Thornton K, Wagner K, Vassilev V, Lin L, Lum PJ, Giudice LC, Stein E, Asher A, Chang S, Gorman R, …
• Dismantling racism against Black, Indigenous, and people of color across the substance use continuum: A position statement of the association for multidisciplinary education and research in substance use and addiction.
  Substance abuse 2021 Hagle HN, Martin M, Winograd R, Merlin J, Finnell DS, Bratberg JP, Gordon AJ, Johnson C, Levy S, MacLane-Baeder D, Northup R, Weinstein Z, Lum PJ
• Accumulation of HIV-1 Drug Resistance Mutations and Methamphetamine Use.
  Current HIV research 2021 Truong HM, Fatch R, Deeks SG, Krone M, Martin JN, Hunt PW, Lum PJ
• Time to ACT: launching an Addiction Care Team (ACT) in an urban safety-net health system.
  BMJ open quality 2021 Martin M, Snyder HR, Coffa D, Steiger S, Clement JP, Ranji SR, Azari S, Nguyen OK, Lum PJ
• Barriers and facilitators to recruitment and enrollment of HIV-infected individuals with opioid use disorder in a clinical trial.
  BMC health services research 2019 Hoffman KA, Baker R, Kunkel LE, Waddell EN, Lum PJ, McCarty D, Korthuis PT
• Rationale and design of a randomized pragmatic trial of patient-centered models of hepatitis C treatment for people who inject drugs: The HERO study.
  Contemporary clinical trials 2019 Litwin AH, Jost J, Wagner K, Heo M, Karasz A, Feinberg J, Kim AY, Lum PJ, Mehta SH, Taylor LE, Tsui JI, Pericot-Valverde I, Page K, HERO Study Group
• Low barrier buprenorphine treatment for persons experiencing homelessness and injecting heroin in San Francisco.
  Addiction science & clinical practice 2019 Carter J, Zevin B, Lum PJ
• Computer-Facilitated 5A's for Smoking Cessation: A Randomized Trial of Technology to Promote Provider Adherence.
  American journal of preventive medicine 2018 Satterfield JM, Gregorich SE, Kalkhoran S, Lum PJ, Bloome J, Alvarado N, Muñoz RF, Vijayaraghavan M
• Continued Transmission of HIV Among Young Adults Who Inject Drugs in San Francisco: Still Room for Improvement.
  AIDS and behavior 2018 Mirzazadeh A, Evans JL, Hahn JA, Jain J, Briceno A, Shiboski S, Lum PJ, Bentsen C, Davis G, Shriver K, Dimapasoc M, Stone M, Busch MP, Page K
• Development and differentiability of three brief interventions for risky alcohol use that include varying doses of motivational interviewing.
  Addiction science & clinical practice 2018 Hettema JE, Cockrell SA, Reeves A, Ingersoll KS, Lum PJ, Saitz R, Murray-Krezan CM, Carrejo VA
• Opioids, Hepatitis C Virus Infection, and the Missing Vaccine.
  American journal of public health 2018 Page K, Cox A, Lum PJ
• Changes in Specific Substance Involvement Scores among SBIRT recipients in an HIV primary care setting.
  Addiction science & clinical practice 2017 Dawson-Rose C, Draughon JE, Cuca Y, Zepf R, Huang E, Cooper BA, Lum PJ
• 2017 HIV Medicine Association of Infectious Diseases Society of America Clinical Practice Guideline for the Management of Chronic Pain in Patients Living With Human Immunodeficiency Virus.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2017 Bruce RD, Merlin J, Lum PJ, Ahmed E, Alexander C, Corbett AH, Foley K, Leonard K, Treisman GJ, Selwyn P
• Integrated HIV care is associated with improved engagement in treatment in an urban methadone clinic.
  Addiction science & clinical practice 2017 Simeone C, Shapiro B, Lum PJ
• Patterns of and reasons for electronic cigarette use in primary care patients.
  Journal of general internal medicine 2017 Kalkhoran S, Alvarado N, Vijayaraghavan M, Lum PJ, Yuan P, Satterfield JM
• Prevalence and predictors of HCV among a cohort of opioid treatment patients in Dar es Salaam, Tanzania.
  The International journal on drug policy 2017 Lambdin BH, Lorvick J, Mbwambo JK, Rwegasha J, Hassan S, Lum P, Kral AH
• Disparities in receipt of 5As for smoking cessation in diverse primary care and HIV clinics.
  Preventive medicine reports 2017 Vijayaraghavan M, Yuan P, Gregorich S, Lum P, Appelle N, Napoles AM, Kalkhoran S, Satterfield J
• Feasibility and safety of extended-release naltrexone treatment of opioid and alcohol use disorder in HIV clinics: a pilot/feasibility randomized trial.
  Addiction (Abingdon, England) 2017 Korthuis PT, Lum PJ, Vergara-Rodriguez P, Ahamad K, Wood E, Kunkel LE, Oden NL, Lindblad R, Sorensen JL, Arenas V, Ha D, Mandler RN, McCarty D, CTN-0055 CHOICES Investigators
• Extended-release naltrexone feasibility in HIV clinics: A pilot study.
  Drug and Alcohol Dependence 2017 Todd Korthuis, Paula J. Lum, P. Vergara-Rodriguez, Keith Ahamad, Evan Wood, R. Lindblad, Raul Mandler, James Sorensen, Doan Ha, Neal Oden, Lynn Kunkel, Dennis McCarty
• A delayed injection-site reaction in a patient receiving extended-release naltrexone.
  Substance abuse 2016 Ahamad K, Korthuis PT, Lum PJ, Johnson C, Wood E
• A Longitudinal Study of Multiple Drug Use and Overdose Among Young People Who Inject Drugs.
  American journal of public health 2016 Riley ED, Evans JL, Hahn JA, Briceno A, Davidson PJ, Lum PJ, Page K
• Comorbid substance use among persons with HIV and chronic pain.
  Chronic Pain and HIV 2016 Paula J. Lum, R. Douglas Bruce
• Prevalence of Substance Use in an HIV Primary Care Safety Net Clinic: A Call for Screening.
  The Journal of the Association of Nurses in AIDS Care : JANAC 2015 Dawson-Rose C, Draughon JE, Zepf R, Cuca YP, Huang E, Freeborn K, Lum PJ
• The longitudinal influence of multiple depressant use on nonfatal overdose among young people who inject drugs.
  Drug and Alcohol Dependence 2015 Elise Riley, Judith A. Hahn, Jennifer L. Evans, Alya Briceno, Peter J. Davidson, Paula J. Lum, Kimberly Page
• Beyond the Ask and Advise: Implementation of a Computer Tablet Intervention to Enhance Provider Adherence to the 5As for Smoking Cessation.
  Journal of substance abuse treatment 2015 Kalkhoran S, Appelle NA, Napoles AM, Munoz RF, Lum PJ, Alvarado N, Gregorich SE, Satterfield JM
• Using Interactive Web-Based Screening, Brief Intervention and Referral to Treatment in an Urban, Safety-Net HIV Clinic.
  AIDS and behavior 2015 Dawson Rose C, Cuca YP, Kamitani E, Eng S, Zepf R, Draughon J, Lum P
• A Skills-Based Curriculum for Teaching Motivational Interviewing-Enhanced Screening, Brief Intervention, and Referral to Treatment (SBIRT) to Medical Residents.
  MedEdPORTAL 2015 Soraya Azari, Neda Ratanawongsa, Jennifer Hettema, Caroline Cangelosi, Matt Tierney, Diana Coffa, Brad Shapiro, Sharad Jain, David Hersh, Jennifer Manuel, Daniel Ciccarone, Paula Lum
• Addressing Adolescent Substance Use: Teaching Screening, Brief Intervention, and Referral to Treatment (SBIRT) and Motivational Interviewing (MI) to Residents.
  Substance abuse 2015 Whittle AE, Buckelew SM, Satterfield JM, Lum PJ, O'Sullivan P
• Association of opioid agonist therapy with lower incidence of hepatitis C virus infection in young adult injection drug users.
  JAMA internal medicine 2014 Tsui JI, Evans JL, Lum PJ, Hahn JA, Page K
• Higher risk of incident hepatitis C virus among young women who inject drugs compared with young men in association with sexual relationships: a prospective analysis from the UFO Study cohort.
  BMJ open 2014 Tracy D, Hahn JA, Fuller Lewis C, Evans J, Briceño A, Morris MD, Lum PJ, Page K
• Ethnically diverse patients' perceptions of clinician computer use in a safety-net clinic.
  Journal of health care for the poor and underserved 2013 Ratanawongsa N, Barton JL, Schillinger D, Yelin EH, Hettema JE, Lum PJ
• Interaction of disulfiram with antiretroviral medications: efavirenz increases while atazanavir decreases disulfiram effect on enzymes of alcohol metabolism.
  The American journal on addictions 2013 McCance-Katz EF, Gruber VA, Beatty G, Lum P, Ma Q, DiFrancesco R, Hochreiter J, Wallace PK, Faiman MD, Morse GD
• Interactions between alcohol and the HIV entry inhibitor Maraviroc.
  Journal of the International Association of Providers of AIDS Care 2013 Gruber VA, Rainey PM, Lum PJ, Beatty GW, Aweeka FT, McCance-Katz EF
• Interactions between alcohol and the antiretroviral medications ritonavir or efavirenz.
  Journal of addiction medicine 2013 McCance-Katz EF, Gruber VA, Beatty G, Lum PJ, Rainey PM
• 8. Implementing Sbirt in Pediatrics: Results of a Needs Assessment.
  Journal of Adolescent Health 2013 Sara M. Buckelew, Amy Whittle, Paula Lum, Patricia O'Sullivan, Jason M. Satterfield
• Smoking cessation interventions with female smokers living with HIV/AIDS: a randomized pilot study of motivational interviewing.
  AIDS care 2012 Manuel JK, Lum PJ, Hengl NS, Sorensen JL
• Frequent longitudinal sampling of hepatitis C virus infection in injection drug users reveals intermittently detectable viremia and reinfection.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2012 Page K, Osburn W, Evans J, Hahn JA, Lum P, Asher A, Delwart E, Tobler L, Cox AL, Busch MP
• Untreated HIV infection is associated with higher blood alcohol levels.
  Journal of acquired immune deficiency syndromes (1999) 2012 McCance-Katz EF, Lum PJ, Beatty G, Gruber VA, Peters M, Rainey PM
• Mortality among young injection drug users in San Francisco: a 10-year follow-up of the UFO study.
  American journal of epidemiology 2012 Evans JL, Tsui JI, Hahn JA, Davidson PJ, Lum PJ, Page K
• A SBIRT curriculum for medical residents: development of a performance feedback tool to build learner confidence.
  Substance abuse 2012 Hettema JE, Ratanawongsa N, Manuel JK, Ciccarone D, Coffa D, Jain S, Lum PJ
• Expectancy and readiness-based predictors of treatment uptake among the urban poor living with HIV.
  Journal of acquired immune deficiency syndromes (1999) 2011 Johnson MO, Dilworth SE, Stephens E, Lum PJ, Neilands TB
• Temporal changes in HCV genotype distribution in three different high risk populations in San Francisco, California.
  BMC infectious diseases 2011 Dias PT, Hahn JA, Delwart E, Edlin B, Martin J, Lum P, Evans J, Kral A, Deeks S, Busch MP, Page K
• Assessing candidacy for acute hepatitis C treatment among active young injection drug users: a case-series report.
  The Journal of the Association of Nurses in AIDS Care : JANAC 2011 Asher A, Lum PJ, Page K
• Drug treatment outcomes among HIV-infected opioid-dependent patients receiving buprenorphine/naloxone.
  Journal of acquired immune deficiency syndromes (1999) 2011 Fiellin DA, Weiss L, Botsko M, Egan JE, Altice FL, Bazerman LB, Chaudhry A, Cunningham CO, Gourevitch MN, Lum PJ, Sullivan LE, Schottenfeld RS, O'Connor PG, BHIVES Collaborative
• HIV treatment outcomes among HIV-infected, opioid-dependent patients receiving buprenorphine/naloxone treatment within HIV clinical care settings: results from a multisite study.
  Journal of acquired immune deficiency syndromes (1999) 2011 Altice FL, Bruce RD, Lucas GM, Lum PJ, Korthuis PT, Flanigan TP, Cunningham CO, Sullivan LE, Vergara-Rodriguez P, Fiellin DA, Cajina A, Botsko M, Nandi V, Gourevitch MN, Finkelstein R, BHIVES …
• Improving adherence to HIV quality of care indicators in persons with opioid dependence: the role of buprenorphine.
  Journal of acquired immune deficiency syndromes (1999) 2011 Korthuis PT, Fiellin DA, Fu R, Lum PJ, Altice FL, Sohler N, Tozzi MJ, Asch SM, Botsko M, Fishl M, Flanigan TP, Boverman J, McCarty D, BHIVES Collaborative
• Opioid-prescribing practices and provider confidence recognizing opioid analgesic abuse in HIV primary care settings.
  Journal of acquired immune deficiency syndromes (1999) 2011 Lum PJ, Little S, Botsko M, Hersh D, Thawley RE, Egan JE, Mitty J, Boverman J, Fiellin DA, BHIVES Collaborative
• The impact of cocaine use on outcomes in HIV-infected patients receiving buprenorphine/naloxone.
  Journal of acquired immune deficiency syndromes (1999) 2011 Sullivan LE, Botsko M, Cunningham CO, O'Connor PG, Hersh D, Mitty J, Lum PJ, Schottenfeld RS, Fiellin DA, BHIVES Collaborative
• HIV vaccine trial willingness among injection and non-injection drug users in two urban centres, Barcelona and San Francisco.
  Vaccine 2011 Etcheverry MF, Lum PJ, Evans JL, Sanchez E, de Lazzari E, Mendez-Arancibia E, Sierra E, Gatell JM, Page K, Joseph J
• HIV intervention for providers study: a randomized controlled trial of a clinician-delivered HIV risk-reduction intervention for HIV-positive people.
  Journal of acquired immune deficiency syndromes (1999) 2010 Rose CD, Courtenay-Quirk C, Knight K, Shade SB, Vittinghoff E, Gomez C, Lum PJ, Bacon O, Colfax G
• Are young injection drug users ready and willing to participate in preventive HCV vaccine trials?
  Vaccine 2010 Levy V, Evans JL, Stein ES, Davidson PJ, Lum PJ, Hahn JA, Page K
• Hepatitis C virus risk behaviors within the partnerships of young injecting drug users.
  Addiction (Abingdon, England) 2010 Hahn JA, Evans JL, Davidson PJ, Lum PJ, Page K
• Acute hepatitis C virus infection in young adult injection drug users: a prospective study of incident infection, resolution, and reinfection.
  The Journal of infectious diseases 2009 Page K, Hahn JA, Evans J, Shiboski S, Lum P, Delwart E, Tobler L, Andrews W, Avanesyan L, Cooper S, Busch MP
• Predictors of injection drug use cessation and relapse in a prospective cohort of young injection drug users in San Francisco, CA (UFO Study).
  Drug and alcohol dependence 2009 Evans JL, Hahn JA, Lum PJ, Stein ES, Page K
• Trends in methamphetamine use in young injection drug users in San Francisco from 1998 to 2004: the UFO Study.
  Drug and alcohol review 2008 Inglez-Dias A, Hahn JA, Lum PJ, Evans J, Davidson P, Page-Shafer K
• Hepatitis B virus infection and immunization status in a new generation of injection drug users in San Francisco.
  Journal of viral hepatitis 2008 Lum PJ, Hahn JA, Shafer KP, Evans JL, Davidson PJ, Stein E, Moss AR
• Traveling young injection drug users at high risk for acquisition and transmission of viral infections.
  Drug and alcohol dependence 2007 Hahn JA, Page-Shafer K, Ford J, Paciorek A, Lum PJ
• Preventing hepatitis C virus infection in injection drug users: risk reduction is not enough.
  AIDS (London, England) 2007 Page-Shafer K, Hahn JA, Lum PJ
• Frequent methamphetamine use is associated with primary non-nucleoside reverse transcriptase inhibitor resistance.
  AIDS (London, England) 2007 Colfax GN, Vittinghoff E, Grant R, Lum P, Spotts G, Hecht FM
• The medical management of opioid dependence in HIV primary care settings.
  Current HIV/AIDS reports 2006 Lum PJ, Tulsky JP
• Commercial sex work and risk of HIV infection among young drug-injecting men who have sex with men in San Francisco.
  Sexually transmitted diseases 2006 Bacon O, Lum P, Hahn J, Evans J, Davidson P, Moss A, Page-Shafer K
• Clinical presentation and course of acute hepatitis C infection in HIV-infected patients.
  Journal of acquired immune deficiency syndromes (1999) 2006 Luetkemeyer A, Hare CB, Stansell J, Tien PC, Charlesbois E, Lum P, Havlir D, Peters M
• Incarceration among young injectors in San Francisco: associations with risk for hepatitis C virus infection.
  Journal of Substance Use 2006 W. Kittikraisak, P. J. Davidson, J. A. Hahn, P. J. Lum, J. L. Evans, A. R. Moss, K. Page-Shafer
• Injection risk behavior among women syringe exchangers in San Francisco.
  Substance use & misuse 2005 Lum PJ, Sears C, Guydish J
• LUM ET AL. RESPOND.
  American Journal of Public Health 2004 Paula J. Lum, Kristen C. Ochoa, Judith A. Hahn, Kimberly Page Shafer, Jennifer L. Evans, Andrew R. Moss
• Hepatitis B virus immunization among young injection drug users in San Francisco, Calif: the UFO Study.
  American journal of public health 2003 Lum PJ, Ochoa KC, Hahn JA, Page Shafer K, Evans JL, Moss AR, UFO Study
• Gender differences in sexual and injection risk behavior among active young injection drug users in San Francisco (the UFO Study).
  Journal of urban health : bulletin of the New York Academy of Medicine 2003 Evans JL, Hahn JA, Page-Shafer K, Lum PJ, Stein ES, Davidson PJ, Moss AR
• Prevalence and correlates of HIV infection among young injection drug users in San Francisco.
  Journal of acquired immune deficiency syndromes (1999) 2002 Shafer KP, Hahn JA, Lum PJ, Ochoa K, Graves A, Moss A
• Hepatitis C virus seroconversion among young injection drug users: relationships and risks.
  The Journal of infectious diseases 2002 Hahn JA, Page-Shafer K, Lum PJ, Bourgois P, Stein E, Evans JL, Busch MP, Tobler LH, Phelps B, Moss AR
• Hepatitis C virus infection and needle exchange use among young injection drug users in San Francisco.
  Hepatology (Baltimore, Md.) 2001 Hahn JA, Page-Shafer K, Lum PJ, Ochoa K, Moss AR
• Investigation of a Secondary Syringe Exchange Program for Homeless Young Adult Injection Drug Users in San Francisco, California, U.S.A.
  JAIDS Journal of Acquired Immune Deficiency Syndromes 2001 Clare Sears, Joseph R. Guydish, Erin K. Weltzien, Paula J. Lum
• Investigation of a Secondary Syringe Exchange Program for Homeless Young Adult Injection Drug Users in San Francisco, California, U.S.A.
  JAIDS Journal of Acquired Immune Deficiency Syndromes 2001 Clare Sears, Joseph R. Guydish, Erin K. Weltzien, Paula J. Lum