Paul Simpson, MD
Professor Emeritus
Medicine
School of Medicine

paul.simpson@ucsf.edu 415-221-4810

I am a clinical cardiologist at the San Francisco VA Medical Center treating inpatients and outpatients with heart disease since 1978. I also direct a lab at the VA, with a main goal to discover new drugs to treat heart failure, a major problem in cardiology.

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The lab has pursued initial findings from the early 1980s to the present, identifying a subclass of receptors for adrenaline as potential targets for a heart failure drug. Efforts in the lab are directed to this new drug, as well as discovering novel aspects of the class of adrenaline receptors. The lab has been funded continuously by the NIH and the VA, with additional important contribution from the AHA.

Education & Training

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  • Clinical Fellow Cardiology Mass General Hospital 1977
  • Resident Medicine University of California 1975
  • Research Fellow Neurobiology NIH, NHLBI 1974
  • Resident Medicine Mass General Hospital 1972
  • MD Medicine Washington Univ School of Medicine 1970
  • BS Biology & Psychology Davidson College 1966

Grants and Projects

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Publications (115)

Top publication keywords:
CardiomegalyMyocardial ContractionReceptors, Adrenergic, betaImidazolesReceptors, Adrenergic, alpha-1TetrahydronaphthalenesNorepinephrineReceptors, Adrenergic, alphaAdrenergic alpha-1 Receptor AgonistsHeartHeart FailureHeart VentriclesMyocardiumCardiotonic AgentsMyocytes, Cardiac

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