Paul Garcia, MD
Professor
Neurology
School of Medicine
I am a neurologist specializing in the treatment of epilepsy. Much of my professional life has been dedicated to building the clinical programs of the UCSF Epilepsy Center. My research is aimed at improving the diagnosis and treatment of people with hard-to-treat epilepsy. My teaching is centered on clinical epilepsy education for fellows, residents and students.
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My university service has been focused on assuring opportunity for students and faculty across the campus. In my role as Associate Dean for Academic Affairs, I am involved with academic review and faculty development for the School of Medicine.
Education & Training
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- Diversity, Equity, and Inclusion Champion Training University of California 2017
- Fellowship Neurology-Epilepsy University of California, San Franciosco 1993
- Residency Neurology University of California, San Franciosco 1991
- Internship Medicine University of California, San Franciosco 1988
- M.D. Medicine University of California, San Francisco 1987
- BS Physiology University of California, Davis 1983
Publications (87)
Top publication keywords:
Anterior Thalamic NucleiDexmedetomidineSeizuresEpilepsy, Temporal LobeAnterior Temporal LobectomyEpilepsyTemporal LobeCreutzfeldt-Jakob SyndromeMemory DisordersElectroencephalographyFunctional LateralityEpilepsies, PartialRadiosurgeryAnticonvulsantsElectric Stimulation Therapy
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Abnormal gamma phase-amplitude coupling in the parahippocampal cortex is associated with network hyperexcitability in Alzheimer’s disease.
Brain Communications 2024 Pooja Prabhu, Hirofumi Morise, Kiwamu Kudo, Alexander Beagle, Danielle Mizuiri, Faatimah Syed, Karunakar A Kotegar, Anne Findlay, Bruce L Miller, Joel H Kramer, Katherine P Rankin, Paul A Garcia, … -
An Innovative Faculty Travel Award Program to Support Child, Elder, or Dependent Care.
JAMA pediatrics 2022 Fuentes-Afflick E, García P, Friedli AB, Johnson B, Binder R -
Factors associated with preoperative and postoperative seizures in patients undergoing resection of brain metastases.
Journal of neurosurgery 2022 Garcia JH, Morshed RA, Chung J, Millares Chavez MA, Sudhakar V, Saggi S, Avalos LN, Gallagher A, Young JS, Daras M, McDermott MW, Garcia PA, Chang EF, Aghi MK -
Impact of COVID-19 on Medical School Faculty.
Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry 2022 Binder R, Garcia P, Friedli A, Fuentes-Afflick E -
Neuronal synchrony abnormalities associated with subclinical epileptiform activity in early-onset Alzheimer's disease.
Brain : a journal of neurology 2022 Ranasinghe KG, Kudo K, Hinkley L, Beagle A, Lerner H, Mizuiri D, Findlay A, Miller BL, Kramer JH, Gorno-Tempini ML, Rabinovici GD, Rankin KP, Garcia PA, Kirsch HE, Vossel K, Nagarajan SS
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The SANTÉ study at 10 years of follow-up: Effectiveness, safety, and sudden unexpected death in epilepsy.
Epilepsia 2021 Salanova V, Sperling MR, Gross RE, Irwin CP, Vollhaber JA, Giftakis JE, Fisher RS, SANTÉ Study Group -
Direct and indirect costs associated with stereotactic radiosurgery or open surgery for medial temporal lobe epilepsy: Results from the ROSE trial.
Epilepsia 2019 Langfitt JT, Quigg M, Yan G, Yu W, Ward MM, Barbaro NM, Chang EF, Broshek DK, Laxer KD, Cole AJ, Sneed PK, Hess C, Tripathi M, Heck CN, Miller JW, Garcia PA, McEvoy A, Fountain NB, Salanova V, … -
Sexual Harassment in Medical Schools: The Challenge of Covert Retaliation as a Barrier to Reporting.
Academic medicine : journal of the Association of American Medical Colleges 2018 Binder R, Garcia P, Johnson B, Fuentes-Afflick E -
Visual field defects after radiosurgery versus temporal lobectomy for mesial temporal lobe epilepsy: Findings of the ROSE trial.
Seizure 2018 Quigg M, Barbaro NM, Ward MM, Chang EF, Broshek DK, Langfitt JT, Yan G, Laxer KD, Cole AJ, Sneed PK, Hess CP, Yu W, Newman SA, Mueller S, Tripathi M, Heck CN, Miller JW, Garcia PA, McEvoy A, Fountain … -
Radiosurgery versus open surgery for mesial temporal lobe epilepsy: The randomized, controlled ROSE trial.
Epilepsia 2018 Barbaro NM, Quigg M, Ward MM, Chang EF, Broshek DK, Langfitt JT, Yan G, Laxer KD, Cole AJ, Sneed PK, Hess CP, Yu W, Tripathi M, Heck CN, Miller JW, Garcia PA, McEvoy A, Fountain NB, Salanova V, … -
Radiation-induced Cavernous Malformation as a Late Sequelae of Stereotactic Radiosurgery for Epilepsy.
Cureus 2018 Winkler EA, Rutledge C, Ward M, Tihan T, Sneed PK, Barbaro N, Garcia P, McDermott M, Chang EF -
Identifying and Mitigating Risk of Violence in the Scientific Workplace.
The journal of the American Academy of Psychiatry and the Law 2017 Binder R, Garcia P, Johnson B, Fuentes-Afflick E -
Memory and mood outcomes after anterior thalamic stimulation for refractory partial epilepsy.
Seizure 2016 Tröster AI, Meador KJ, Irwin CP, Fisher RS, SANTE Study Group -
Incidence and impact of subclinical epileptiform activity in Alzheimer's disease.
Annals of neurology 2016 Vossel KA, Ranasinghe KG, Beagle AJ, Mizuiri D, Honma SM, Dowling AF, Darwish SM, Van Berlo V, Barnes DE, Mantle M, Karydas AM, Coppola G, Roberson ED, Miller BL, Garcia PA, Kirsch HE, Mucke L, … -
Timing and significance of pathological features in C9orf72 expansion-associated frontotemporal dementia.
Brain : a journal of neurology 2016 Vatsavayai SC, Yoon SJ, Gardner RC, Gendron TF, Vargas JN, Trujillo A, Pribadi M, Phillips JJ, Gaus SE, Hixson JD, Garcia PA, Rabinovici GD, Coppola G, Geschwind DH, Petrucelli L, Miller BL, Seeley WW -
Corpus callosotomy versus vagus nerve stimulation for atonic seizures and drop attacks: A systematic review.
Epilepsy & behavior : E&B 2015 Rolston JD, Englot DJ, Wang DD, Garcia PA, Chang EF -
Long-term efficacy and safety of thalamic stimulation for drug-resistant partial epilepsy.
Neurology 2015 Salanova V, Witt T, Worth R, Henry TR, Gross RE, Nazzaro JM, Labar D, Sperling MR, Sharan A, Sandok E, Handforth A, Stern JM, Chung S, Henderson JM, French J, Baltuch G, Rosenfeld WE, Garcia P, … -
Factors associated with failed focal neocortical epilepsy surgery.
Neurosurgery 2014 Englot DJ, Raygor KP, Molinaro AM, Garcia PA, Knowlton RC, Auguste KI, Chang EF -
Unilateral holohemispheric central nervous system lesions associated with medically refractory epilepsy in the pediatric population: a retrospective series of hemimegalencephaly and Rasmussen's encephalitis.
Journal of neurosurgery. Pediatrics 2014 Wang DD, Benkli B, Auguste KI, Garcia PA, Sullivan J, Barkovich AJ, Chang EF, Tihan T -
Enzyme-inducing anticonvulsants increase plasma clearance of dexmedetomidine: a pharmacokinetic and pharmacodynamic study.
Anesthesiology 2014 Flexman AM, Wong H, Riggs KW, Shih T, Garcia PA, Vacas S, Talke PO -
Seizure types and frequency in patients who "fail" temporal lobectomy for intractable epilepsy.
Neurosurgery 2013 Englot DJ, Lee AT, Tsai C, Halabi C, Barbaro NM, Auguste KI, Garcia PA, Chang EF -
Quinacrine treatment trial for sporadic Creutzfeldt-Jakob disease.
Neurology 2013 Geschwind MD, Kuo AL, Wong KS, Haman A, Devereux G, Raudabaugh BJ, Johnson DY, Torres-Chae CC, Finley R, Garcia P, Thai JN, Cheng HQ, Neuhaus JM, Forner SA, Duncan JL, Possin KL, Dearmond SJ, Prusiner… -
Seizures and epileptiform activity in the early stages of Alzheimer disease.
JAMA neurology 2013 Vossel KA, Beagle AJ, Rabinovici GD, Shu H, Lee SE, Naasan G, Hegde M, Cornes SB, Henry ML, Nelson AB, Seeley WW, Geschwind MD, Gorno-Tempini ML, Shih T, Kirsch HE, Garcia PA, Miller BL, Mucke L -
Distinguishing language and race disparities in epilepsy surgery.
Epilepsy & behavior : E&B 2013 Betjemann JP, Thompson AC, Santos-Sánchez C, Garcia PA, Ivey SL -
Visual field defects after radiosurgery for mesial temporal lobe epilepsy.
Epilepsia 2013 Hensley-Judge H, Quigg M, Barbaro NM, Newman SA, Ward MM, Chang EF, Broshek DK, Lamborn KR, Laxer KD, Garcia P, Heck CN, Kondziolka D, Beach R, Salanova V, Goodman R -
Exaggerated phase-amplitude coupling in the primary motor cortex in Parkinson disease.
Proceedings of the National Academy of Sciences of the United States of America 2013 de Hemptinne C, Ryapolova-Webb ES, Air EL, Garcia PA, Miller KJ, Ojemann JG, Ostrem JL, Galifianakis NB, Starr PA -
A two-level multimodality imaging Bayesian network approach for classification of partial epilepsy: preliminary data.
NeuroImage 2013 Mueller SG, Young K, Hartig M, Barakos J, Garcia P, Laxer KD -
Transmantle sign in focal cortical dysplasia: a unique radiological entity with excellent prognosis for seizure control.
Journal of neurosurgery 2012 Wang DD, Deans AE, Barkovich AJ, Tihan T, Barbaro NM, Garcia PA, Chang EF -
Differential diagnosis of Jakob-Creutzfeldt disease.
Archives of neurology 2012 Paterson RW, Torres-Chae CC, Kuo AL, Ando T, Nguyen EA, Wong K, DeArmond SJ, Haman A, Garcia P, Johnson DY, Miller BL, Geschwind MD -
Seizure exacerbation in two patients with focal epilepsy following marijuana cessation.
Epilepsy & behavior : E&B 2012 Hegde M, Santos-Sanchez C, Hess CP, Kabir AA, Garcia PA -
Relationship between hospital surgical volume, lobectomy rates, and adverse perioperative events at US epilepsy centers.
Journal of neurosurgery 2012 Englot DJ, Ouyang D, Wang DD, Rolston JD, Garcia PA, Chang EF -
Long-term seizure control outcomes after resection of gangliogliomas.
Neurosurgery 2012 Southwell DG, Garcia PA, Berger MS, Barbaro NM, Chang EF -
Minocycline- and tetracycline-class antibiotics are protective against partial seizures in vivo.
Epilepsy & behavior : E&B 2012 Wang DD, Englot DJ, Garcia PA, Lawton MT, Young WL -
Clinical overlap between Jakob-Creutzfeldt disease and Lewy body disease.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 2012 Tartaglia MC, Johnson DY, Thai JN, Cattaruzza T, Wong K, Garcia P, Dearmond SJ, Miller BL, Geschwind MD -
Characteristics and treatment of seizures in patients with high-grade glioma: a review.
Neurosurgery clinics of North America 2012 Englot DJ, Berger MS, Chang EF, Garcia PA -
Epilepsy surgery trends in the United States, 1990-2008.
Neurology 2012 Englot DJ, Ouyang D, Garcia PA, Barbaro NM, Chang EF -
Impact of methodologic choice for automatic detection of different aspects of brain atrophy by using temporal lobe epilepsy as a model.
AJNR. American journal of neuroradiology 2011 Scanlon C, Mueller SG, Tosun D, Cheong I, Garcia P, Barakos J, Weiner MW, Laxer KD -
Predictors of seizure freedom after surgery for malformations of cortical development.
Annals of neurology 2011 Chang EF, Wang DD, Barkovich AJ, Tihan T, Auguste KI, Sullivan JE, Garcia PA, Barbaro NM -
Different structural correlates for verbal memory impairment in temporal lobe epilepsy with and without mesial temporal lobe sclerosis.
Human brain mapping 2011 Mueller SG, Laxer KD, Scanlon C, Garcia P, McMullen WJ, Loring DW, Meador KJ, Weiner MW -
Neuropsychological outcomes after Gamma Knife radiosurgery for mesial temporal lobe epilepsy: a prospective multicenter study.
Epilepsia 2011 Quigg M, Broshek DK, Barbaro NM, Ward MM, Laxer KD, Yan G, Lamborn K, Radiosurgery Epilepsy Study Group -
Widespread extrahippocampal NAA/(Cr+Cho) abnormalities in TLE with and without mesial temporal sclerosis.
Journal of neurology 2010 Mueller SG, Ebel A, Barakos J, Scanlon C, Cheong I, Finlay D, Garcia P, Weiner MW, Laxer KD -
Electrical stimulation of the anterior nucleus of thalamus for treatment of refractory epilepsy.
Epilepsia 2010 Fisher R, Salanova V, Witt T, Worth R, Henry T, Gross R, Oommen K, Osorio I, Nazzaro J, Labar D, Kaplitt M, Sperling M, Sandok E, Neal J, Handforth A, Stern J, DeSalles A, Chung S, Shetter A, Bergen D… -
Predictors of efficacy after stereotactic radiosurgery for medial temporal lobe epilepsy.
Neurology 2010 Chang EF, Quigg M, Oh MC, Dillon WP, Ward MM, Laxer KD, Broshek DK, Barbaro NM, Epilepsy Radiosurgery Study Group -
Seizure control outcomes after resection of dysembryoplastic neuroepithelial tumor in 50 patients.
Journal of neurosurgery. Pediatrics 2010 Chang EF, Christie C, Sullivan JE, Garcia PA, Tihan T, Gupta N, Berger MS, Barbaro NM -
Characteristics of auras in patients undergoing temporal lobectomy.
Journal of neurosurgery 2009 Binder DK, Garcia PA, Elangovan GK, Barbaro NM -
Involvement of the thalamocortical network in TLE with and without mesiotemporal sclerosis.
Epilepsia 2009 Mueller SG, Laxer KD, Barakos J, Cheong I, Finlay D, Garcia P, Cardenas-Nicolson V, Weiner MW -
Examination of volunteer bias in research involving patients diagnosed with psychogenic nonepileptic seizures.
Epilepsy & behavior : E&B 2009 Taylor AM, Cahn-Weiner DA, Garcia PA -
Seizure characteristics and control after microsurgical resection of supratentorial cerebral cavernous malformations.
Neurosurgery 2009 Chang EF, Gabriel RA, Potts MB, Garcia PA, Barbaro NM, Lawton MT -
Subfield atrophy pattern in temporal lobe epilepsy with and without mesial sclerosis detected by high-resolution MRI at 4 Tesla: preliminary results.
Epilepsia 2009 Mueller SG, Laxer KD, Barakos J, Cheong I, Garcia P, Weiner MW -
Widespread neocortical abnormalities in temporal lobe epilepsy with and without mesial sclerosis.
NeuroImage 2009 Mueller SG, Laxer KD, Barakos J, Cheong I, Garcia P, Weiner MW -
A multicenter, prospective pilot study of gamma knife radiosurgery for mesial temporal lobe epilepsy: seizure response, adverse events, and verbal memory.
Annals of neurology 2009 Barbaro NM, Quigg M, Broshek DK, Ward MM, Lamborn KR, Laxer KD, Larson DA, Dillon W, Verhey L, Garcia P, Steiner L, Heck C, Kondziolka D, Beach R, Olivero W, Witt TC, Salanova V, Goodman R -
Correlating DWI MRI with pathologic and other features of Jakob-Creutzfeldt disease.
Alzheimer disease and associated disorders 2009 Geschwind MD, Potter CA, Sattavat M, Garcia PA, Rosen HJ, Miller BL, DeArmond SJ -
Patients with seizure clusters--identification of a high-risk group.
Epilepsy currents 2009 Garcia P -
Is seizure surgery an option for patients with very low IQ?
Epilepsy currents 2008 Garcia P -
Seizure remission in adults with intractable epilepsy: not just a pipe dream.
Epilepsy currents 2008 Garcia P -
Imaging depression in epilepsy: hints at the biology of despair.
Epilepsy currents 2007 Garcia PA -
Dexmedetomidine does not reduce epileptiform discharges in adults with epilepsy.
Journal of neurosurgical anesthesiology 2007 Talke P, Stapelfeldt C, Garcia P -
Nonconvulsive seizures in the pediatric intensive care unit: out of sight, out of mind?
Epilepsy currents 2007 Garcia P -
Brain stimulation for epilepsy: stimulating results?
Epilepsy currents 2006 Garcia P -
Medical intractability and imaging: can MRI predict the future?
Epilepsy currents 2006 Garcia P -
Speech preservation during language-dominant, left temporal lobe seizures: report of a rare, potentially misleading finding.
Epilepsia 2006 Kaiboriboon K, Parent JM, Barbaro NM, Walker JA, Garcia PA -
Mood disorders and epilepsy surgery: lightening the burden in more ways than one?
Epilepsy currents 2006 Garcia PA -
Impact of epilepsy surgery on developing minds: how do we weigh the consequences?
Epilepsy currents 2006 Garcia PA -
Limitations of Wada memory asymmetry as a predictor of outcomes after temporal lobectomy.
Neurology 2005 Kirsch HE, Walker JA, Winstanley FS, Hendrickson R, Wong ST, Barbaro NM, Laxer KD, Garcia PA -
Surgery for heterotopia: a second look.
Epilepsy currents 2005 Garcia PA -
Clinical features of status epilepticus in patients with HIV infection.
Neurology 2005 Lee KC, Garcia PA, Alldredge BK -
Magnetoencephalography source localization and surgical outcome in temporal lobe epilepsy.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2004 Assaf BA, Karkar KM, Laxer KD, Garcia PA, Austin EJ, Barbaro NM, Aminoff MJ -
Ictal magnetoencephalography in temporal and extratemporal lobe epilepsy.
Epilepsia 2003 Assaf BA, Karkar KM, Laxer KD, Garcia PA, Austin EJ, Barbaro NM, Aminoff MJ -
Differential cognitive and behavioral effects of topiramate and valproate.
Neurology 2003 Meador KJ, Loring DW, Hulihan JF, Kamin M, Karim R, CAPSS-027 Study Group -
Potentially misleading extratemporal lobe lesions in patients with temporal lobe epilepsy.
Journal of neurology, neurosurgery, and psychiatry 2003 Alsaadi TM, Bateman LM, Laxer KD, Barbaro NM, Austin EJ, Garcia PA -
Zonisamide-induced restless legs syndrome.
Neurology 2003 Chen JT, Garcia PA, Alldredge BK -
Focal cooling suppresses spontaneous epileptiform activity without changing the cortical motor threshold.
Epilepsia 2002 Karkar KM, Garcia PA, Bateman LM, Smyth MD, Barbaro NM, Berger M -
Incidence and mortality of generalized convulsive status epilepticus in California.
Neurology 2002 Wu YW, Shek DW, Garcia PA, Zhao S, Johnston SC -
False lateralization by subdural electrodes in two patients with temporal lobe epilepsy.
Neurology 2001 Alsaadi TM, Laxer KD, Barbaro NM, Marks WJ, Garcia PA -
Vagus nerve stimulation for the treatment of bilateral independent temporal lobe epilepsy.
Epilepsia 2001 Alsaadi TM, Laxer KD, Barbaro NM, Marks WJ, Garcia PA -
Management of seizures and epilepsy.
American family physician 1998 Marks WJ, Garcia PA -
Correlation of seizure frequency with N-acetyl-aspartate levels determined by 1H magnetic resonance spectroscopic imaging.
Magnetic resonance imaging 1997 Garcia PA, Laxer KD, van der Grond J, Hugg JW, Matson GB, Weiner MW -
Magnetic resonance spectroscopy.
Neuroimaging clinics of North America 1995 Garcia PA, Laxer KD -
The frontal N30 component of the median-derived SEP in patients with predominantly unilateral Parkinson's disease.
Neurology 1995 Garcia PA, Aminoff MJ, Goodin DS -
Proton magnetic resonance spectroscopic imaging in patients with frontal lobe epilepsy.
Annals of neurology 1995 Garcia PA, Laxer KD, van der Grond J, Hugg JW, Matson GB, Weiner MW -
Application of spectroscopic imaging in epilepsy.
Magnetic resonance imaging 1995 Garcia PA, Laxer KD, Ng T -
Prognostic value of qualitative magnetic resonance imaging hippocampal abnormalities in patients undergoing temporal lobectomy for medically refractory seizures.
Epilepsia 1994 Garcia PA, Laxer KD, Barbaro NM, Dillon WP -
Drug-induced seizures.
Neurologic clinics 1994 Garcia PA, Alldredge BK -
Phosphorus magnetic resonance spectroscopic imaging in patients with frontal lobe epilepsy.
Annals of neurology 1994 Garcia PA, Laxer KD, van der Grond J, Hugg JW, Matson GB, Weiner MW -
Neurological reactions in HIV-infected patients treated with trichosanthin.
Neuropathology and applied neurobiology 1993 Garcia PA, Bredesen DE, Vinters HV, Graefin von Einsiedel R, Williams RL, Kahn JO, Byers VS, Levin AS, Waites LA, Messing RO -
Imaging criteria to identify the epileptic focus. Magnetic resonance imaging, magnetic resonance spectroscopy, positron emission tomography scanning, and single photon emission computed tomography.
Neurosurgery clinics of North America 1993 Laxer KD, Garcia PA -
The prognostic value of postoperative seizures following epilepsy surgery.
Neurology 1991 Garcia PA, Barbaro NM, Laxer KD