Patrick Phillips, PhD, MS, MA
Associate Professor
Medicine
School of Medicine

patrick.phillips@ucsf.edu

As part of the UCSF Center for Tuberculosis, I am Associate Professor in Residence in the Division of Pulmonary and Critical Care Medicine with a secondary appointment in the Department of Epidemiology and Biostatistics. Prior to 2017 I was senior statistician at the MRC Clinical Trials Unit at UCL in London.

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The objective of my research is to design, implement, and optimize clinical trials for new treatments for tuberculosis in order to deliver safer and more efficacious regimens for patients. I lead the Trial Design and Statistics core of the PanACEA consortium evaluating novel regimens for the treatment of TB, am consultant statistician for the US CDC-funded TB Trials Consortium (TBTC), and a member of the ACTG TB Transformative Science Steering Group. I have worked on late-phase clinical trials in tuberculosis for more than fifteen years, most recently as trial statistician in the STREAM Stage 1 and the TBTC/ACTG S31/A5349 phase III trials and vice-chair of ACTG A5414 SPECTR-TB. Ongoing methodological areas of interest include the evaluation and use of surrogate endpoints, the conduct and analysis of non-inferiority trials and trial design with a focus on adaptive designs. I am an associate editor for the journal BMC Trials.

Education & Training

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  • PDip Postgraduate Diploma of the LSHTM by research in Epidemiology and Population Health London School of Hygiene and Tropical Medicine, University of London 2010
  • PhD Medical Statistics London School of Hygiene and Tropical Medicine, University of London 2009
  • MA Mathematics Clare College, University of Cambridge 2007
  • MSc Biometry University of Reading 2005
  • BA Hons Mathematics Clare College, University of Cambridge 2003

Interests

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  • Clinical trials
  • Clinical trial design
  • Surrogate endpoints
  • Trials methodology
  • Tuberculosis
  • Adaptive trial designs
  • Non-inferiority trials

Websites

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Grants and Projects

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Publications (148)

Top publication keywords:
SputumTuberculosis, PulmonaryTuberculosis, Multidrug-ResistantRifampinEthambutolPyrazinamideTuberculosisClinical Trials, Phase III as TopicIsoniazidMycobacterium tuberculosisAntitubercular AgentsFluoroquinolonesResearch DesignAntibiotics, AntitubercularLatent Tuberculosis

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