Patrick Pfaff, PhD, MSc
Postdoctoral Scholar
Cellular Molecular Pharmacology
School of Medicine

Publications (5)

Top publication keywords:
Cannabinoid Receptor AgonistsMolecular StructureOptical ImagingCHO CellsPhotochemical ProcessesCannabinoidsMolecular Docking SimulationCalciumReceptor, Cannabinoid, CB2Alzheimer DiseaseMicrogliaFluorescent DyesCricetulusFluorescence Resonance Energy TransferMolecular Probes

• Detection of cannabinoid receptor type 2 in native cells and zebrafish with a highly potent, cell-permeable fluorescent probe.
  Chemical science 2022 Gazzi T, Brennecke B, Atz K, Korn C, Sykes D, Forn-Cuni G, Pfaff P, Sarott RC, Westphal MV, Mostinski Y, Mach L, Wasinska-Kalwa M, Weise M, Hoare BL, Miljuš T, Mexi M, Roth N, Koers EJ, Guba W, Alker …
• Azoacetylenes for the Synthesis of Arylazotriazole Photoswitches.
  Journal of the American Chemical Society 2021 Pfaff P, Anderl F, Fink M, Balkenhohl M, Carreira EM
• Optical Control of Cannabinoid Receptor 2-Mediated Ca2+ Release Enabled by Synthesis of Photoswitchable Probes.
  Journal of the American Chemical Society 2021 Sarott RC, Viray AEG, Pfaff P, Sadybekov A, Rajic G, Katritch V, Carreira EM, Frank JA
• Development of High-Specificity Fluorescent Probes to Enable Cannabinoid Type 2 Receptor Studies in Living Cells.
  Journal of the American Chemical Society 2020 Sarott RC, Westphal MV, Pfaff P, Korn C, Sykes DA, Gazzi T, Brennecke B, Atz K, Weise M, Mostinski Y, Hompluem P, Koers E, Miljuš T, Roth NJ, Asmelash H, Vong MC, Piovesan J, Guba W, Rufer AC, Kusznir…
• Reversible Spatiotemporal Control of Induced Protein Degradation by Bistable PhotoPROTACs.
  ACS central science 2019 Pfaff P, Samarasinghe KTG, Crews CM, Carreira EM