Patricia Arean, PhD
Professor
Psychiatry
School of Medicine

Websites

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• Profile at UCSF Department of Psychiatry (psych.ucsf.edu)

Grants and Projects

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• Clinical Services Research Training Program, NIH, 1985-2026
• Enhancing Engagement with Digital Mental Health Care, NIH, 2020-2024
• Using Search Engine Data for Detection and Early Intervention in Suicide Prevention, NIH, 2021-2024
• UW ALACRITY Center for Psychosocial Interventions Research, NIH, 2018-2022
• A Computerized Intervention Targeting Cognitive Control Network Deficits in Depression, NIH, 2016-2021
• Enhancing Cognitive Control in Older Adults with Complementary Interventions, NIH, 2015-2020
• 2/2 Stepped, reward-exposure based therapy vs. PST in late life depression, NIH, 2014-2020
• Scaling a smarter and more efficient intervention: Evaluating the feasibility of disseminating a novel mobile app platform to treat depression, NIH, 2016-2019
• A Computerized Intervention Targeting Cognitive Control Network Deficits in Depression, NIH, 2016-2018
• Strategic and Plasticity Interventions for Late Life Depression in Community Settings, NIH, 2005-2017
• Can mental health apps work in the real world? A feasibility pilot study, NIH, 2013-2017
• CATALAC: Community-Academic Treatment & Assessment for Low-Income Aged Consumers, NIH, 2008-2014
• Case Management and PST for Depressed Homebound Low-Income Elders, NIH, 2007-2013
• Community-Academic Research Training Alliance (CARTA), NIH, 2005-2011
• PST in Geriatric Depression with Executive Dysfunction, NIH, 2002-2008
• Treatments for Depressed Elderly Primary Care Patients, NIH, 1994-2000

Publications (65)

Top publication keywords:
Behavior TherapyMental Health ServicesTelemedicineText MessagingDepressive Disorder, MajorMental HealthProblem SolvingRemission InductionExecutive FunctionPsychotherapyApathyMobile ApplicationsPain, IntractableDepressionDepressive Disorder

• Correction: Digital and precision clinical trials: innovations for testing mental health medications, devices, and psychosocial treatments.
  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2024 Lenze E, Torous J, Arean P
• Digital and precision clinical trials: innovations for testing mental health medications, devices, and psychosocial treatments.
  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2023 Lenze E, Torous J, Arean P
• Effectiveness of Mental Health Apps for Distress During COVID-19 in US Unemployed and Essential Workers: Remote Pragmatic Randomized Clinical Trial.
  JMIR mHealth and uHealth 2022 Comtois KA, Mata-Greve F, Johnson M, Pullmann MD, Mosser B, Arean P
• Participant retention in a fully remote trial of digital psychotherapy: Comparison of incentive types.
  Frontiers in digital health 2022 Griffith Fillipo IR, Pullmann MD, Hull TD, Zech J, Wu J, Litvin B, Chen S, Arean PA
• Message-based psychotherapy for older adults: A cohort comparison study.
  Frontiers in psychiatry 2022 Raue PJ, Fridling N, Song J, Hull TD, Alexopoulos GS, Arean PA

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• Protocol for a sequential, multiple assignment, randomised trial to test the effectiveness of message-based psychotherapy for depression compared with telepsychotherapy.
  BMJ open 2021 Arean P, Hull D, Pullmann MD, Heagerty PJ
• Toward a Mobile Platform for Real-world Digital Measurement of Depression: User-Centered Design, Data Quality, and Behavioral and Clinical Modeling.
  JMIR mental health 2021 Nickels S, Edwards MD, Poole SF, Winter D, Gronsbell J, Rozenkrants B, Miller DP, Fleck M, McLean A, Peterson B, Chen Y, Hwang A, Rust-Smith D, Brant A, Campbell A, Chen C, Walter C, Arean PA, Hsin H,…
• Mental Health and the Perceived Usability of Digital Mental Health Tools Among Essential Workers and People Unemployed Due to COVID-19: Cross-sectional Survey Study.
  JMIR mental health 2021 Mata-Greve F, Johnson M, Pullmann MD, Friedman EC, Griffith Fillipo I, Comtois KA, Arean P
• Association Between Care Utilization and Anxiety Outcomes in an On-Demand Mental Health System: Retrospective Observational Study.
  JMIR formative research 2021 Kunkle S, Yip M, Hunt J, ? W, Udall D, Arean P, Nierenberg A, Naslund JA
• A randomized controlled trial of internet-delivered cognitive behaviour therapy to prevent the development of depressive disorders in older adults with multimorbidity.
  Journal of affective disorders 2019 Read J, Sharpe L, Burton AL, Arean PA, Raue PJ, McDonald S, Titov N, Gandy M, Dear BF
• Towards a consensus around standards for smartphone apps and digital mental health.
  World psychiatry : official journal of the World Psychiatric Association (WPA) 2019 Torous J, Andersson G, Bertagnoli A, Christensen H, Cuijpers P, Firth J, Haim A, Hsin H, Hollis C, Lewis S, Mohr DC, Pratap A, Roux S, Sherrill J, Arean PA
• Corrigendum to 'Does Cognition Predict Treatment Response and Remission in Psychotherapy for Late-Life Depression?' [The American Journal of Geriatric Psychiatry 23 (2015) 215-219].
  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2018 Beaudreau SA, Rideaux T, O'Hara R, Arean P
• Using Mobile Apps to Assess and Treat Depression in Hispanic and Latino Populations: Fully Remote Randomized Clinical Trial.
  Journal of medical Internet research 2018 Pratap A, Renn BN, Volponi J, Mooney SD, Gazzaley A, Arean PA, Anguera JA
• "Engage" therapy: Prediction of change of late-life major depression.
  Journal of affective disorders 2017 Alexopoulos GS, O'Neil R, Banerjee S, Raue PJ, Victoria LW, Bress JN, Pollari C, Arean PA
• Pain severity predicts depressive symptoms over and above individual illnesses and multimorbidity in older adults.
  BMC psychiatry 2017 Sharpe L, McDonald S, Correia H, Raue PJ, Meade T, Nicholas M, Arean P
• The feasibility, acceptability, and outcomes of PRIME-D: A novel mobile intervention treatment for depression.
  Depression and anxiety 2017 Schlosser DA, Campellone TR, Truong B, Anguera JA, Vergani S, Vinogradov S, Arean P
• The Use and Effectiveness of Mobile Apps for Depression: Results From a Fully Remote Clinical Trial.
  Journal of medical Internet research 2016 Arean PA, Hallgren KA, Jordan JT, Gazzaley A, Atkins DC, Heagerty PJ, Anguera JA
• Mental Health Service Use Across the Life Course Among Adults With Psychiatric Disorders and Prior Suicidal Behavior.
  Psychiatric services (Washington, D.C.) 2016 Byers AL, Lai AX, Arean P, Nelson JC, Yaffe K
• "Engage" Therapy: Behavioral Activation and Improvement of Late-Life Major Depression.
  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2015 Alexopoulos GS, Raue PJ, Gunning F, Kiosses DN, Kanellopoulos D, Pollari C, Banerjee S, Arean PA
• The Sociocultural Context of Caregiving Experiences for Vietnamese Dementia Family Caregivers.
  Asian American journal of psychology 2015 Meyer OL, Nguyen KH, Dao TN, Vu P, Arean P, Hinton L
• Role of Executive Dysfunction and Dysexecutive Behavior in Late-Life Depression and Disability.
  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2015 Gansler DA, Suvak M, Arean P, Alexopoulos GS
• Depression Treatment Uptake in Integrated Primary Care: How a "Warm Handoff" and Other Factors Affect Decision Making by Latinos.
  Psychiatric services (Washington, D.C.) 2015 Horevitz E, Organista KC, Arean PA
• Causal and bidirectional linkages over time between depression and diabetes regimen distress in adults with type 2 diabetes.
  Diabetes research and clinical practice 2015 Hessler D, Fisher L, Strycker LA, Arean PA, Bowyer V
• Does cognition predict treatment response and remission in psychotherapy for late-life depression?
  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2014 Beaudreau SA, Rideaux T, O'Hara R, Arean P
• Comparing engage with PST in late-life major depression: a preliminary report.
  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2014 Alexopoulos GS, Raue PJ, Kiosses DN, Seirup JK, Banerjee S, Arean PA
• Choosing treatment for depression in older adults and evaluating response.
  Clinics in geriatric medicine 2014 Arean PA, Niu G
• Do manualized treatments for depression reduce insomnia symptoms?
  Journal of clinical psychology 2014 Yon A, Scogin F, DiNapoli EA, McPherron J, Arean PA, Bowman D, Jamison CS, Karpe JA, Latour D, Reynolds CF, Rohen N, Pardini JE, Thompson LW
• Association of age at depression onset with cognitive functioning in individuals with late-life depression and executive dysfunction.
  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2014 Mackin RS, Nelson JC, Delucchi KL, Raue PJ, Satre DD, Kiosses DN, Alexopoulos GS, Arean PA
• A model for streamlining psychotherapy in the RDoC era: the example of 'Engage'.
  Molecular psychiatry 2013 Alexopoulos GS, Arean P
• Cognitive outcomes after psychotherapeutic interventions for major depression in older adults with executive dysfunction.
  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2013 Mackin RS, Nelson JC, Delucchi K, Raue P, Byers A, Barnes D, Satre DD, Yaffe K, Alexopoulos GS, Arean PA
• Reductions in regimen distress are associated with improved management and glycemic control over time.
  Diabetes care 2013 Hessler D, Fisher L, Glasgow RE, Strycker LA, Dickinson LM, Arean PA, Masharani U
• REDEEM: a pragmatic trial to reduce diabetes distress.
  Diabetes care 2013 Fisher L, Hessler D, Glasgow RE, Arean PA, Masharani U, Naranjo D, Strycker LA
• Patterns of reduced cortical thickness in late-life depression and relationship to psychotherapeutic response.
  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2013 Mackin RS, Tosun D, Mueller SG, Lee JY, Insel P, Schuff N, Truran-Sacrey D, Arean P, Nelson JC, Weiner MW
• Implementation Research: Reducing the Research-to-Practice Gap in Depression Treatment.
  Depression research and treatment 2012 Kilbourne AM, Williams M, Bauer MS, Arean P
• Implementing evidence-based psychotherapies in settings serving older adults: challenges and solutions.
  Psychiatric services (Washington, D.C.) 2012 Arean PA, Raue PJ, Sirey JA, Snowden M
• Depression is a common and chronic comorbidity in patients with interstitial lung disease.
  Respirology (Carlton, Vic.) 2012 Ryerson CJ, Arean PA, Berkeley J, Carrieri-Kohlman VL, Pantilat SZ, Landefeld CS, Collard HR
• Personalizing behavioral interventions: the case of late-life depression.
  Neuropsychiatry 2012 Arean PA
• Low use of mental health services among older Americans with mood and anxiety disorders.
  Psychiatric services (Washington, D.C.) 2012 Byers AL, Arean PA, Yaffe K
• High-Yield Cognitive-Behavior Therapy for Brief Sessions: An Illustrated Guideby Wright Jesse H. Sudak Donna M. Turkington Douglas and Thase Michael E. Washington, DC , American Psychiatric Publishing , 2010 , 383 pp., $74.00 .
  The American journal of psychiatry 2010 Arean PA
• Home-delivered problem adaptation therapy (PATH) for depressed, cognitively impaired, disabled elders: A preliminary study.
  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2010 Kiosses DN, Arean PA, Teri L, Alexopoulos GS
• Research on late-life depression and dementia care: across disciplines, across settings.
  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2010 Kiosses DN, Arean PA
• Does mentoring matter: results from a survey of faculty mentees at a large health sciences university.
  Medical education online 2010 Feldman MD, Arean PA, Marshall SJ, Lovett M, O'Sullivan P
• Advantages of using estimated depression-free days for evaluating treatment efficacy.
  Psychiatric services (Washington, D.C.) 2010 Vannoy SD, Arean P, Unützer J
• Diabetes distress but not clinical depression or depressive symptoms is associated with glycemic control in both cross-sectional and longitudinal analyses.
  Diabetes care 2009 Fisher L, Mullan JT, Arean P, Glasgow RE, Hessler D, Masharani U
• The selection and design of control conditions for randomized controlled trials of psychological interventions.
  Psychotherapy and psychosomatics 2009 Mohr DC, Spring B, Freedland KE, Beckner V, Arean P, Hollon SD, Ockene J, Kaplan R
• Predicting diabetes distress in patients with Type 2 diabetes: a longitudinal study.
  Diabetic medicine : a journal of the British Diabetic Association 2009 Fisher L, Mullan JT, Skaff MM, Glasgow RE, Arean P, Hessler D
• Long term care staff beliefs about evidence based practices for the management of dementia and agitation.
  International journal of geriatric psychiatry 2009 Ayalon L, Arean P, Bornfeld H, Beard R
• A longitudinal study of affective and anxiety disorders, depressive affect and diabetes distress in adults with Type 2 diabetes.
  Diabetic medicine : a journal of the British Diabetic Association 2008 Fisher L, Skaff MM, Mullan JT, Arean P, Glasgow R, Masharani U
• Problem solving therapy for the depression-executive dysfunction syndrome of late life.
  International journal of geriatric psychiatry 2008 Alexopoulos GS, Raue PJ, Kanellopoulos D, Mackin S, Arean PA
• Effectiveness of problem-solving therapy for older, primary care patients with depression: results from the IMPACT project.
  The Gerontologist 2008 Arean P, Hegel M, Vannoy S, Fan MY, Unuzter J
• Developing an intervention for depressed, chronically medically ill elders: a model from COPD.
  International journal of geriatric psychiatry 2008 Alexopoulos GS, Raue PJ, Sirey JA, Arean PA
• Correlates of knowledge and beliefs about depression among long-term care staff.
  International journal of geriatric psychiatry 2008 Ayalon L, Arean P, Bornfeld H
• The role of cognitive functioning and distress in suicidal ideation in older adults.
  Journal of the American Geriatrics Society 2007 Ayalon L, Mackin S, Arean PA, Chen H, McDonel Herr EC
• Clinical depression versus distress among patients with type 2 diabetes: not just a question of semantics.
  Diabetes care 2007 Fisher L, Skaff MM, Mullan JT, Arean P, Mohr D, Masharani U, Glasgow R, Laurencin G
• Long term outcomes from the IMPACT randomised trial for depressed elderly patients in primary care.
  BMJ (Clinical research ed.) 2006 Hunkeler EM, Katon W, Tang L, Williams JW, Kroenke K, Lin EH, Harpole LH, Arean P, Levine S, Grypma LM, Hargreaves WA, Unützer J
• Effect of improving depression care on pain and functional outcomes among older adults with arthritis: a randomized controlled trial.
  JAMA 2003 Lin EH, Katon W, Von Korff M, Tang L, Williams JW, Kroenke K, Hunkeler E, Harpole L, Hegel M, Arean P, Hoffing M, Della Penna R, Langston C, Unützer J, IMPACT Investigators
• Depression and Bipolar Support Alliance consensus statement on the unmet needs in diagnosis and treatment of mood disorders in late life.
  Archives of general psychiatry 2003 Charney DS, Reynolds CF, Lewis L, Lebowitz BD, Sunderland T, Alexopoulos GS, Blazer DG, Katz IR, Meyers BS, Arean PA, Borson S, Brown C, Bruce ML, Callahan CM, Charlson ME, Conwell Y, Cuthbert BN, …
• Impacting late life depression: integrating a depression intervention into primary care.
  The Psychiatric quarterly 2003 Oishi SM, Shoai R, Katon W, Callahan C, Unützer J, Arean P, Callahan C, Della Penna R, Harpole L, Hegel M, Noel PH, Hoffing M, Hunkeler EM, Katon W, Levine S, Lin EH, Oddone E, Oishi S, Unützer J, …
• Ethical considerations in psychotherapy effectiveness research: choosing the comparison group.
  Ethics & behavior 2002 Arean PA, Alvidrez J
• Psychosocial treatment research with ethnic minority populations: ethical considerations in conducting clinical trials.
  Ethics & behavior 2002 Alvidrez J, Arean PA
• Improving primary care for depression in late life: the design of a multicenter randomized trial.
  Medical care 2001 Unützer J, Katon W, Williams JW, Callahan CM, Harpole L, Hunkeler EM, Hoffing M, Arean P, Hegel MT, Schoenbaum M, Oishi SM, Langston CA
• Methods for studying course of illness with severely mentally ill adults.
  Issues in mental health nursing 1997 Chafetz L, Havassy B, Arean P
• Do primary care patients accept psychological treatments?
  General hospital psychiatry 1996 Arean PA, Miranda J
• Comparative effectiveness of social problem-solving therapy and reminiscence therapy as treatments for depression in older adults.
  Journal of consulting and clinical psychology 1993 Arean PA, Perri MG, Nezu AM, Schein RL, Christopher F, Joseph TX
• Assertiveness and problem-solving training for mildly mentally retarded persons with dual diagnoses.
  Research in developmental disabilities 1991 Nezu CM, Nezu AM, Arean P