Pamela Murnane, PhD, MPH
Assistant Professor
Epidemiology & Biostatistics
School of Medicine

Pam Murnane is an Assistant Professor in the department of Epidemiology & Biostatistics at UCSF. Her research focusses on biological, behavioral, and structural factors that influence maternal and child health outcomes in the context of HIV in resource limited settings. She has expertise in epidemiologic methods, adherence measurement, risk prediction, and implementation science.

Education & Training

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• Diversity, Equity, and Inclusion Champion Training University of California 2019
• MPH Epidemiology Columbia University
• MLIS Library and Information Science San Jose State University
• Postdoctoral fellowship Center for AIDS Prevention Studies University of California
• PhD Epidemiology University of Washington

Interests

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• Women's health
• Maternal & infant health
• clinical trials
• Global health
• HIV
• implementation science
• sub-Saharan Africa
• risk prediction
• measurement of treatment adherence
• causal inference

Grants and Projects

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• Implementing a risk score to facilitate enhanced adherence support for pregnant and postpartum women at risk of viremia, NIH, 2019-2024

Publications (40)

Top publication keywords:
BenzoxazinesMedication AdherenceLopinavirEmtricitabine, Tenofovir Disoproxil Fumarate Drug CombinationPerinatal CareAnti-Retroviral AgentsTenofovirViremiaHairRitonavirInfectious Disease Transmission, VerticalAnti-HIV AgentsPre-Exposure ProphylaxisHIV InfectionsNevirapine

• Using Phosphatidylethanol as an Adjunct to Self-Reported Alcohol Use Improves Identification of Liver Fibrosis Risk.
  The American journal of gastroenterology 2024 Murnane PM, Afshar M, Chamie G, Cook RL, Ferguson T, Haque LY, Jacobson KR, Justice AC, Kim TW, Khalili M, Krupitsky E, McGinnis KA, Molina P, Muyindike WR, Myers B, Richards VL, So-Armah K, Stewart S…
• Evaluation of person-centered interventions to eliminate perinatal HIV transmission in Kisumu County, Kenya: A repeated cross-sectional study using aggregated registry data.
  PLoS medicine 2024 Odhiambo F, Onyango R, Mulwa E, Aluda M, Otieno L, Bukusi EA, Cohen CR, Murnane PM
• Geographic Mobility and HIV Care Engagement among People Living with HIV in Rural Kenya and Uganda.
  Tropical medicine and infectious disease 2023 Ayieko J, Thorp M, Getahun M, Gandhi M, Maeri I, Gutin SA, Okiring J, Kamya MR, Bukusi EA, Charlebois ED, Petersen M, Havlir DV, Camlin CS, Murnane PM
• First cases of SARS-CoV-2 infection and secondary transmission in Kisumu, Kenya.
  PLOS global public health 2022 Tippett Barr BA, Herman-Roloff A, Mburu M, Murnane PM, Sang N, Bukusi E, Oele E, Odhiambo A, Lewis-Kulzer J, Onyango CO, Hunsperger E, Odhiambo F, Joseph RH, Munyua P, Othieno K, Mulwa E, Akelo V, …
• Analysis of Heavy Rainfall in Sub-Saharan Africa and HIV Transmission Risk, HIV Prevalence, and Sexually Transmitted Infections, 2005-2017.
  JAMA network open 2022 Nagata JM, Hampshire K, Epstein A, Lin F, Zakaras J, Murnane P, Charlebois ED, Tsai AC, Nash D, Weiser SD

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• Antiretroviral Therapy Adherence During and Postbreastfeeding Cessation Measured by Tenofovir Levels in Hair.
  Journal of acquired immune deficiency syndromes (1999) 2022 Nematadzira TG, Murnane PM, Odiase OJ, Bacchetti P, Okochi H, Tallerico R, Chanaiwa VM, Vhembo T, Mutambanengwe-Jacob MT, Louie A, Chipato T, Gandhi M, Stranix-Chibanda L, IMPAACT PROMISE Study Team
• Associations Between Anabolic-Androgenic Steroid Use and Sexual Health Behaviors Among Adolescent Boys: Results From the 2019 Youth Risk Behavior Survey.
  American journal of men's health 2022 Ganson KT, Jackson DB, Testa A, Murnane PM, Nagata JM
• Distinct forms of migration and mobility are differentially associated with HIV treatment adherence.
  AIDS (London, England) 2022 Murnane PM, Gandhi M, Bacchetti P, Getahun M, Gutin SA, Okochi H, Maeri I, Eyul P, Omoding D, Okiring J, Tallerico R, Louie A, Akullian A, Kamya MR, Bukusi EA, Charlebois ED, Camlin CS
• Disclosure to South African children about their own HIV status over time.
  AIDS care 2021 Wu M, Shiau S, Strehlau R, Liberty A, Patel F, Burke M, Murnane PM, Violari A, Yin MT, Abrams EJ, Kuhn L, Arpadi S
• Machine Learning Algorithms Using Routinely Collected Data Do Not Adequately Predict Viremia to Inform Targeted Services in Postpartum Women Living With HIV.
  Journal of acquired immune deficiency syndromes (1999) 2021 Murnane PM, Ayieko J, Vittinghoff E, Gandhi M, Katumbi C, Milala B, Nakaye C, Kanda P, Moodley D, Nyati ME, Loftis AJ, Fowler MG, Flynn P, Currier JS, Cohen CR
• Performance-Enhancing Substance Use and Sexual Risk Behaviors among U.S. Men: Results from a Prospective Cohort Study.
  Journal of sex research 2021 Ganson KT, Jackson DB, Testa A, Murnane PM, Nagata JM
• Factors associated with phosphatidylethanol (PEth) sensitivity for detecting unhealthy alcohol use: An individual patient data meta-analysis.
  Alcoholism, clinical and experimental research 2021 Hahn JA, Murnane PM, Vittinghoff E, Muyindike WR, Emenyonu NI, Fatch R, Chamie G, Haberer JE, Francis JM, Kapiga S, Jacobson K, Myers B, Couture MC, DiClemente RJ, Brown JL, So-Armah K, Sulkowski M, …
• Perinatal Food Insecurity and Postpartum Psychosocial Stress are Positively Associated Among Kenyan Women of Mixed HIV Status.
  AIDS and behavior 2020 Murnane PM, Miller JD, Tuthill EL, Collins SM, Neilands TB, Onono M, Cohen CR, Weiser SD, Laudenslager ML, Young SL
• Short- and Long-Term Pharmacologic Measures of HIV Pre-exposure Prophylaxis Use Among High-Risk Men Who Have Sex With Men in HPTN 067/ADAPT.
  Journal of acquired immune deficiency syndromes (1999) 2019 Velloza J, Bacchetti P, Hendrix CW, Murnane P, Hughes JP, Li M, Curlin ME, Holtz TH, Mannheimer S, Marzinke MA, Amico KR, Liu A, Piwowar-Manning E, Eshleman SH, Dye BJ, Gandhi M, Grant RM, HPTN 067/…
• Tenofovir concentrations in hair strongly predict virologic suppression in breastfeeding women.
  AIDS (London, England) 2019 Murnane PM, Bacchetti P, Currier JS, Brummel S, Okochi H, Phung N, Louie A, Kuncze K, Hoffman RM, Nematadzira T, Soko DK, Owor M, Saidi F, Flynn PM, Fowler MG, Gandhi M
• Research priorities to inform "Treat All" policy implementation for people living with HIV in sub-Saharan Africa: a consensus statement from the International epidemiology Databases to Evaluate AIDS (IeDEA).
  Journal of the International AIDS Society 2019 Yotebieng M, Brazier E, Addison D, Kimmel AD, Cornell M, Keiser O, Parcesepe AM, Onovo A, Lancaster KE, Castelnuovo B, Murnane PM, Cohen CR, Vreeman RC, Davies MA, Duda SN, Yiannoutsos CT, Bono RS, …
• Achieving UNAIDS 90-90-90 targets for pregnant and postpartum women in sub-Saharan Africa: progress, gaps and research needs.
  Journal of virus eradication 2018 Abuogi LL, Humphrey JM, Mpody C, Yotebieng M, Murnane PM, Clouse K, Otieno L, Cohen CR, Wools-Kaloustian K
• 12-month outcomes of HIV-infected infants identified at birth at one maternity site in Johannesburg, South Africa: an observational cohort study.
  The lancet. HIV 2018 Technau KG, Strehlau R, Patel F, Shiau S, Burke M, Conradie M, Sorour G, Sherman GG, Coovadia A, Murnane PM, Abrams EJ, Kuhn L
• Reply to Van de Wijer et al.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2018 Murnane PM, Strehlau R, Shiau S, Patel F, Mbete N, Hunt G, Abrams EJ, Coovadia A, Kuhn L
• Modeling HIV disease progression and transmission at population-level: The potential impact of modifying disease progression in HIV treatment programs.
  Epidemics 2017 Ross JM, Ying R, Celum CL, Baeten JM, Thomas KK, Murnane PM, van Rooyen H, Hughes JP, Barnabas RV
• Hair levels of preexposure prophylaxis drugs measure adherence and are associated with renal decline among men/transwomen.
  AIDS (London, England) 2017 Gandhi M, Murnane PM, Bacchetti P, Elion R, Kolber MA, Cohen SE, Horng H, Louie A, Kuncze K, Koss CA, Anderson PL, Buchbinder S, Liu A
• Prevalence and outcomes of HIV-1 diagnostic challenges during universal birth testing - an urban South African observational cohort.
  Journal of the International AIDS Society 2017 Technau KG, Mazanderani AH, Kuhn L, Hans L, Strehlau R, Abrams EJ, Conradie M, Coovadia A, Mbete N, Murnane PM, Patel F, Shiau S, Tiemessen CT, Sherman GG
• Switching to Efavirenz Versus Remaining on Ritonavir-boosted Lopinavir in Human Immunodeficiency Virus-infected Children Exposed to Nevirapine: Long-term Outcomes of a Randomized Trial.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2017 Murnane PM, Strehlau R, Shiau S, Patel F, Mbete N, Hunt G, Abrams EJ, Coovadia A, Kuhn L
• Xpert HIV-1 point-of-care test for neonatal diagnosis of HIV in the birth testing programme of a maternity hospital: a field evaluation study.
  The lancet. HIV 2017 Technau KG, Kuhn L, Coovadia A, Murnane PM, Sherman G
• Extent of disclosure: what perinatally HIV-infected children have been told about their own HIV status.
  AIDS care 2016 Murnane PM, Sigamoney SL, Pinillos F, Shiau S, Strehlau R, Patel F, Liberty A, Abrams EJ, Arpadi S, Coovadia A, Violari A, Kuhn L
• Regulatory T-Cell Activity But Not Conventional HIV-Specific T-Cell Responses Are Associated With Protection From HIV-1 Infection.
  Journal of acquired immune deficiency syndromes (1999) 2016 Pattacini L, Baeten JM, Thomas KK, Fluharty TR, Murnane PM, Donnell D, Bukusi E, Ronald A, Mugo N, Lingappa JR, Celum C, McElrath MJ, Lund JM, Partners PrEP Study Team
• Estimating efficacy in a randomized trial with product nonadherence: application of multiple methods to a trial of preexposure prophylaxis for HIV prevention.
  American journal of epidemiology 2015 Murnane PM, Brown ER, Donnell D, Coley RY, Mugo N, Mujugira A, Celum C, Baeten JM, Partners PrEP Study Team
• Murnane, Coley, and Baeten respond to "every good randomization deserves observation".
  American journal of epidemiology 2015 Murnane PM, Coley RY, Baeten JM
• Estimating PMTCT's Impact on Heterosexual HIV Transmission: A Mathematical Modeling Analysis.
  PloS one 2015 Khanna AS, Roberts ST, Cassels S, Ying R, John-Stewart G, Goodreau SM, Baeten JM, Murnane PM, Celum C, Barnabas RV
• Antiretroviral Pre-Exposure Prophylaxis Does Not Enhance Immune Responses to HIV in Exposed but Uninfected Persons.
  The Journal of infectious diseases 2014 Pattacini L, Murnane PM, Baeten JM, Fluharty TR, Thomas KK, Bukusi E, Katabira E, Mugo N, Donnell D, Lingappa JR, Celum C, Marzinke M, McElrath MJ, Lund JM, Partners PrEP Study Team
• Initiation of antiretroviral therapy and viral suppression after home HIV testing and counselling in KwaZulu-Natal, South Africa, and Mbarara district, Uganda: a prospective, observational intervention study.
  The lancet. HIV 2014 Barnabas RV, van Rooyen H, Tumwesigye E, Murnane PM, Baeten JM, Humphries H, Turyamureeba B, Joseph P, Krows M, Hughes JP, Celum C
• Pre-exposure prophylaxis for HIV-1 prevention does not diminish the pregnancy prevention effectiveness of hormonal contraception.
  AIDS (London, England) 2014 Murnane PM, Heffron R, Ronald A, Bukusi EA, Donnell D, Mugo NR, Were E, Mujugira A, Kiarie J, Celum C, Baeten JM, Partners PrEP Study Team
• Enhanced and efficient detection of virus-driven cytokine expression by human NK and T cells.
  Journal of virological methods 2014 Pattacini L, Murnane PM, Fluharty TR, Katabira E, De Rosa SC, Baeten JM, Lund JM
• High HIV testing uptake and linkage to care in a novel program of home-based HIV counseling and testing with facilitated referral in KwaZulu-Natal, South Africa.
  Journal of acquired immune deficiency syndromes (1999) 2013 van Rooyen H, Barnabas RV, Baeten JM, Phakathi Z, Joseph P, Krows M, Hong T, Murnane PM, Hughes J, Celum C
• Efficacy of preexposure prophylaxis for HIV-1 prevention among high-risk heterosexuals: subgroup analyses from a randomized trial.
  AIDS (London, England) 2013 Murnane PM, Celum C, Mugo N, Campbell JD, Donnell D, Bukusi E, Mujugira A, Tappero J, Kahle EM, Thomas KK, Baeten JM, Partners PrEP Study Team
• Differential regulatory T cell activity in HIV type 1-exposed seronegative individuals.
  AIDS research and human retroviruses 2013 Pattacini L, Murnane PM, Kahle EM, Bolton MJ, Delrow JJ, Lingappa JR, Katabira E, Donnell D, McElrath MJ, Baeten JM, Lund JM
• Household-based HIV counseling and testing as a platform for referral to HIV care and medical male circumcision in Uganda: a pilot evaluation.
  PloS one 2012 Tumwebaze H, Tumwesigye E, Baeten JM, Kurth AE, Revall J, Murnane PM, Chang LW, Celum C
• Using plasma viral load to guide antiretroviral therapy initiation to prevent HIV-1 transmission.
  PloS one 2012 Murnane PM, Hughes JP, Celum C, Lingappa JR, Mugo N, Farquhar C, Kiarie J, Wald A, Baeten JM, Partners in Prevention HSV/HIV Transmission Study Team
• Lactation-associated postpartum weight changes among HIV-infected women in Zambia.
  International journal of epidemiology 2010 Murnane PM, Arpadi SM, Sinkala M, Kankasa C, Mwiya M, Kasonde P, Thea DM, Aldrovandi GM, Kuhn L
• Behavioral influences on preterm birth: a review.
  Epidemiology (Cambridge, Mass.) 2010 Savitz DA, Murnane P