P. Daniel Knott, MD
Professor
Otolaryngology
School of Medicine
P. Daniel Knott, MD, is a Professor in the Facial Plastic, Aesthetic and Reconstructive Surgery Division, and he is the Director of Facial Plastic and Aesthetic Surgery in Department of Otolaryngology – Head and Neck Surgery (OHNS) at the University of California, San Francisco. Dr. Knott received his medical degree from the University of California, San Diego in La Jolla.
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He completed a one-year General Surgery internship from the Cleveland Clinic in Ohio, and a five-year OHNS residency from the same institution, followed by a Facial Plastic and Reconstructive Surgery fellowship from the University of California, Los Angeles Medical Center.
Dr. Knott particularly specializes in artificial tissue and tissue engineering applications. He has extensive experience on the full spectrum of facial anesthetic operations and treatments, with great focus of the reconstruction of traumatic, malignant, and congenital defects of the head and neck. He also has experience in creating solutions for the two common issues that affect the face over time - treating the descent of the soft tissues and facial soft tissue atrophy.
Dr. Knott’s clinical research has focused on the novel applications, morbidities, and recipient potential of the antero-lateral thigh free flap. He has been using free flap in many innovative ways including, pharyngeal, nasal, scalp, and mid-facial reconstruction. Dr. Knott continues his research efforts in the basic science sphere, which focuses on the broad concept of cartilage bioengineering. Along with cross-sectional colleagues, Dr. Knott has patented a technique of cross-linking collagen and hyaluronic acid using a tyramine-based chemical process. The cross-linking can be performed across a wide spectrum of concentrations, yielding a variety of biomaterials of differing strengths, shear resistances, and biomechanical properties.
Dr. Knott has authored over 30 peer-reviewed papers and serves as a peer reviewer on topics related to facial plastic and reconstructive surgery for multiple national journals including, Head and Neck Surgery, JAMA Facial Plastic Surgery, Laryngoscope, the International Journal of Dermatology, and Otolaryngology-Head and Neck Surgery. Dr. Knott has authored six book chapters on facial aesthetic surgery and published a book on the aesthetic use of botox.
Specialty: Facial Plastic, Aesthetic and Reconstructive Surgery
Expertise: Rhinoplasty, treatment of facial aging, treatment of facial paralysis, reconstruction of facial cutaneous malignancies, and free tissue transfer
Professional Interests: Facial paralysis, microvascular facial reconstruction, free tissue transfer, maxillary reconstruction
Education and Training:
- Medical School: University of California, San Diego, La Jolla
- Internship: Cleveland Clinic, OH – General Surgery
- Residency: Cleveland Clinic, OH – Otolaryngology – Head and Neck Surgery
- Fellowship: University of California, Los Angeles Medical Center– Facial Plastic and Reconstructive Surgery
- Medical Licensure, California
- Medical Licensure, Ohio
- Board Certification, Otolaryngology - Head and Neck Surgery
- Board Certification, Facial Plastic and Reconstructive Surgery
Awards
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- Kaiser Teacher of the Year Award-Inpatient Care, UCSF Medical Center, 2012-2013
- Roger Boles Teaching Award, UCSF Department of Otolaryngology/Head and Neck Surgery, 2011-2012
- Ira Tresley Research Award, American Academy of Facial Plastic and Reconstructive Surgery, 2008-2009
- Ben Shuster Memorial Award, American Academy of Facial Plastic and Reconstructive Surgery, 2007-2008
- Robert Maxwell Byers Award, American Head and Neck Society, 2006-2007
Education & Training
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- M.D. School of Medicine University of California San Diego 2000
Websites
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- Clinical Profile at UCSF Medical Center (ucsfhealth.org)
Publications (28)
Top publication keywords:
HyperostosisMandibleSurgery, Computer-AssistedFacial InjuriesFibrous Dysplasia of BoneParanasal SinusesSurgical FlapsSkull NeoplasmsPolyestersReceptors, Antigen, T-Cell, alpha-betaTissue and Organ HarvestingOsteonecrosisBone TransplantationLarynxEsthetics
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Hepatitis C as a Potential Risk Factor for Adverse Surgical Outcomes in Head and Neck Free Tissue Transfer Reconstruction.
Facial plastic surgery & aesthetic medicine 2021 Callander JK, Strohl MP, Knott PD, Park A, Seth R, Heaton CM -
Hyperostotic esthesioneuroblastoma: rare variant and fibrous dysplasia mimicker.
Korean journal of radiology 2014 Ahmed M, Knott PD -
Motor nerve to the vastus lateralis.
Archives of facial plastic surgery 2012 Revenaugh PC, Knott D, McBride JM, Fritz MA -
Orbitomaxillary reconstruction using the layered fibula osteocutaneous flap.
Archives of facial plastic surgery 2012 Shipchandler TZ, Waters HH, Knott PD, Fritz MA -
Simultaneous anterolateral thigh flap and temporalis tendon transfer to optimize facial form and function after radical parotidectomy.
Archives of facial plastic surgery 2012 Revenaugh PC, Knott PD, Scharpf J, Fritz MA
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A 12-year perspective on the world's first total laryngeal transplant.
Transplantation 2011 Knott PD, Hicks D, Braun W, Strome M -
Volume-directed facial soft tissue deficit reconstruction.
Facial plastic surgery : FPS 2010 Seth R, Nabili V, Fritz MA, Alam DS, Knott PD -
Outcomes of vascularized bone graft reconstruction of the mandible in bisphosphonate-related osteonecrosis of the jaws.
The Laryngoscope 2010 Seth R, Futran ND, Alam DS, Knott PD -
Minimally invasive endoscopic resection of sinonasal undifferentiated carcinoma.
American journal of otolaryngology 2010 Revenaugh PC, Seth R, Pavlovich JB, Knott PD, Batra PS -
Spontaneous cerebrospinal fluid rhinorrhea as the initial presentation of growth hormone-secreting pituitary adenoma.
American journal of otolaryngology 2010 Makin V, Hatipoglu B, Hamrahian AH, Arrossi AV, Knott PD, Lee JH, Sade B -
Vascularized bone graft reconstruction of the temporomandibular joint using the tunneled, anchored suture technique.
The Laryngoscope 2010 Seth R, Waters HH, Knott PD -
A novel bioabsorbable device for facial suspension and rejuvenation.
Archives of facial plastic surgery 2009 Knott PD, Newman J, Keller GS, Apfelberg DB -
Induction with T-cell receptor antibody leads to long-term laryngeal allograft function.
American journal of otolaryngology 2008 Knott PD, Dan O, Strome M -
Advanced lip reconstruction: functional and aesthetic considerations.
Facial plastic surgery : FPS 2008 Nabili V, Knott PD -
Evaluation of hardware-related complications in vascularized bone grafts with locking mandibular reconstruction plate fixation.
Archives of otolaryngology--head & neck surgery 2007 Knott PD, Suh JD, Nabili V, Sercarz JA, Head C, Abemayor E, Blackwell KE -
RAD inhibition of sarcoma growth: implications for laryngeal transplantation.
American journal of otolaryngology 2007 Knott PD, Tamai H, Strome M, Van Lente F, Shu S -
A comparison of dermabond tissue adhesive and sutures in the primary repair of the congenital cleft lip.
Annals of plastic surgery 2007 Knott PD, Zins JE, Banbury J, Djohan R, Yetman RJ, Papay F -
Vocal outcomes after laser resection of early-stage glottic cancer with adjuvant cryotherapy.
Archives of otolaryngology--head & neck surgery 2006 Knott PD, Milstein CF, Hicks DM, Abelson TI, Byrd MC, Strome M -
Contour and paired-point registration in a model for image-guided surgery.
The Laryngoscope 2006 Knott PD, Batra PS, Butler RS, Citardi MJ -
Vocal fold healing after laser cordectomy with adjuvant cryotherapy.
The Laryngoscope 2006 Knott PD, Byrd MC, Hicks DG, Strome M -
Computer aided surgery: concepts and applications in rhinology.
Otolaryngologic clinics of North America 2006 Knott PD, Batra PS, Citardi MJ -
Pulsed immunosuppression with everolimus and anti-alphabeta T-cell receptor: laryngeal allograft preservation at six months.
The Annals of otology, rhinology, and laryngology 2006 Khariwala SS, Knott PD, Dan O, Klimczak A, Siemionow M, Strome M -
Hemophilia B and free tissue transfer: medical and surgical management.
Annals of plastic surgery 2005 Knott PD, Khariwala SS, Minarchek J -
High-frequency ultrasound in the measurement of pediatric craniofacial integrity.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2004 Knott PD, Hazony D, Karafa M, Koltai PJ -
The impact of fiducial distribution on headset-based registration in image-guided sinus surgery.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2004 Knott PD, Maurer CR, Gallivan R, Roh HJ, Citardi MJ -
Stepped-dose protocol of cidofovir therapy in recurrent respiratory papillomatosis in children.
Archives of otolaryngology--head & neck surgery 2003 Akst LM, Lee W, Discolo C, Knott D, Younes A, Koltai PJ -
Mesenchymal chondrosarcoma of the sinonasal tract: a clinicopathological study of 13 cases with a review of the literature.
The Laryngoscope 2003 Knott PD, Gannon FH, Thompson LD -
Sensorineural hearing loss and Kawasaki disease: a prospective study.
American journal of otolaryngology 2001 Knott PD, Orloff LA, Harris JP, Novak RE, Burns JC, Kawasaki Disease Multicenter Hearing Loss Study Group