Omar Khan, MD, PhD
Assistant Professor
Laboratory Medicine
School of Medicine

Publications (67)

Top publication keywords:
Global HealthPrejudiceInternational Educational ExchangeGastric BypassInterferon-betaGastrectomyHealth Care CostsRed-Cell Aplasia, PurePhysicians, Primary CareMaternal DeathMultiple Sclerosis, Relapsing-RemittingObesity, MorbidParaproteinemiasMultiple SclerosisBariatric Surgery

• Global Health in an Interconnected World: Opportunities and Challenges.
  Delaware journal of public health 2025 Khan OA
• Monoclonal Gammopathy of Anemic Significance? Resolution of Pure Red Cell Aplasia With Daratumumab-Based Therapy.
  The American journal of medicine 2024 Khan O, Prakash S, Chung A, Wong SW, Kennedy VE
• Family Medicine Training in The US and Delaware:: Opportunities and Growth in Primary Care Workforce.
  Delaware journal of public health 2023 Khan OA, Kavanaugh EM, Monteleone RA, Vasagar B, Robert JF
• Atezolizumab plus cabozantinib versus cabozantinib monotherapy for patients with renal cell carcinoma after progression with previous immune checkpoint inhibitor treatment (CONTACT-03): a multicentre, randomised, open-label, phase 3 trial.
  Lancet (London, England) 2023 Pal SK, Albiges L, Tomczak P, Suárez C, Voss MH, de Velasco G, Chahoud J, Mochalova A, Procopio G, Mahammedi H, Zengerling F, Kim C, Osawa T, Angel M, Gupta S, Khan O, Bergthold G, Liu B, Kalaitzidou …
• Impact of Moderate Aortic Stenosis in Patients With Heart Failure With Reduced Ejection Fraction.
  Journal of the American College of Cardiology 2023 Khan KR, Khan OA, Chen C, Liu Y, Kandanelly RR, Jamiel PJ, Tanguturi V, Hung J, Inglessis I, Passeri JJ, Langer NB, Elmariah S

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• Clinical characteristics of patients undergoing primary bariatric surgery in the United Kingdom based on the National Bariatric Surgery Registry.
  Clinical obesity 2023 Bolckmans R, Askari A, Currie A, Ahmed AR, Batterham RL, Byrne J, Hopkins J, Khan OA, Mahawar K, Miras AD, Pring CM, Small PK, Welbourn R
• Gastrojejunostomy Closure Technique and Risk of Leak: an Evaluation in Ex Vivo Porcine Models.
  Obesity surgery 2023 Das B, Ledesma F, Ashrafian H, Reddy M, Khan OA, Fehervari M
• Welcome from the Delaware Health Sciences Alliance.
  Delaware journal of public health 2022 Khan OA, Gardner P
• Adjuvant atezolizumab versus placebo for patients with renal cell carcinoma at increased risk of recurrence following resection (IMmotion010): a multicentre, randomised, double-blind, phase 3 trial.
  Lancet (London, England) 2022 Pal SK, Uzzo R, Karam JA, Master VA, Donskov F, Suarez C, Albiges L, Rini B, Tomita Y, Kann AG, Procopio G, Massari F, Zibelman M, Antonyan I, Huseni M, Basu D, Ci B, Leung W, Khan O, Dubey S, Bex A
• The Case Against Race-Based GFR.
  Delaware journal of public health 2022 Uppal P, Golden BL, Panicker A, Khan OA, Burday MJ
• From the Guest Editors.
  Delaware journal of public health 2022 Eppes SC, Khan OA
• Final Overall Survival and Molecular Analysis in IMmotion151, a Phase 3 Trial Comparing Atezolizumab Plus Bevacizumab vs Sunitinib in Patients With Previously Untreated Metastatic Renal Cell Carcinoma.
  JAMA oncology 2022 Motzer RJ, Powles T, Atkins MB, Escudier B, McDermott DF, Alekseev BY, Lee JL, Suarez C, Stroyakovskiy D, De Giorgi U, Donskov F, Mellado B, Banchereau R, Hamidi H, Khan O, Craine V, Huseni M, Flinn N…
• Frataxin deficiency promotes endothelial senescence in pulmonary hypertension.
  The Journal of clinical investigation 2021 Culley MK, Zhao J, Tai YY, Tang Y, Perk D, Negi V, Yu Q, Woodcock CC, Handen A, Speyer G, Kim S, Lai YC, Satoh T, Watson AM, Aaraj YA, Sembrat J, Rojas M, Goncharov D, Goncharova EA, Khan OF, Anderson…
• Obstructive sleep apnea remission following bariatric surgery: a national registry cohort study.
  Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery 2021 Currie AC, Kaur V, Carey I, Al-Rubaye H, Mahawar K, Madhok B, Small P, McGlone ER, Khan OA
• Differential effects of bile acids on the postprandial secretion of gut hormones: a randomized crossover study.
  American journal of physiology. Endocrinology and metabolism 2021 McGlone ER, Malallah K, Cuenco J, Wewer Albrechtsen NJ, Holst JJ, Vincent RP, Ling C, Khan OA, Verma S, Ahmed AR, Walters JRF, Khoo B, Bloom SR, Tan TMM
• Bariatric surgery for patients with type 2 diabetes mellitus requiring insulin: Clinical outcome and cost-effectiveness analyses.
  PLoS medicine 2020 McGlone ER, Carey I, Velickovic V, Chana P, Mahawar K, Batterham RL, Hopkins J, Walton P, Kinsman R, Byrne J, Somers S, Kerrigan D, Menon V, Borg C, Ahmed A, Sgromo B, Cheruvu C, Bano G, Leonard C, …
• An Invited Commentary on "Comparative risk of fracture for bariatric procedures in patients with obesity: A systematic review and Bayesian network meta-analysis" (Int J Surg 2020; 75: 13-23) - Metabolic effects of bariatric surgery.
  International journal of surgery (London, England) 2020 Lo C, Khan OA
• Clinical and Echocardiographic Predictors of Outcomes in Patients With Moderate (Mean Transvalvular Gradient 20 to 40 mm Hg) Aortic Stenosis.
  The American journal of cardiology 2019 Murphy KR, Khan OA, Rassa AC, Elman MR, Chadderdon SM, Song HK, Golwala H, Cigarroa JE, Zahr FE
• Increased blood pressure visit-to-visit variability in patients with systemic lupus erythematosus: association with inflammation and comorbidity burden.
  Lupus 2019 Reese T, Dickson AL, Shuey MM, Gandelman JS, Barnado A, Barker KA, Neal JE, Khan OA, Dupont WD, Stein CM, Chung CP
• BOLA (BolA Family Member 3) Deficiency Controls Endothelial Metabolism and Glycine Homeostasis in Pulmonary Hypertension.
  Circulation 2019 Yu Q, Tai YY, Tang Y, Zhao J, Negi V, Culley MK, Pilli J, Sun W, Brugger K, Mayr J, Saggar R, Saggar R, Wallace WD, Ross DJ, Waxman AB, Wendell SG, Mullett SJ, Sembrat J, Rojas M, Khan OF, Dahlman JE,…
• Dear Editor.
  Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery 2018 McGlone ER, Khan OA, Maynard W, Hopkins J, Dexter S, Finlay I, Hewin D, Sedman P, Walton P, Somers S, Reddy M, Small P, Adamo M, Welbourn R
• Single-stage conversions from failed gastric band to sleeve gastrectomy versus Roux-en-Y gastric bypass: results from the United Kingdom National Bariatric Surgical Registry.
  Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery 2018 Khan OA, McGlone ER, Maynard W, Hopkins J, Dexter S, Finlay I, Hewin D, Sedman P, Walton P, Somers S, Reddy M, Small P, Adamo M, Welbourn R
• A pilot study of primary care physicians' attitude to weight loss surgery in England: are the young more prejudiced?
  Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery 2017 McGlone ER, Wingfield LR, Munasinghe A, Batterham RL, Reddy M, Khan OA
• Late onset neuromyelitis optica mimicking an acute stroke in an elderly patient.
  Journal of neuroimmunology 2017 Suchdev K, Razmjou S, Venkatachalam P, Khan OA, Mohamed W, Ibrahim MS
• Place Matters: At the Intersection of Delaware Medicine and Population Health.
  Delaware journal of public health 2016 Gibbs TE, NPMc,1, Khan OA, Meara DJ
• Proliferation and Recruitment Contribute to Myocardial Macrophage Expansion in Chronic Heart Failure.
  Circulation research 2016 Sager HB, Hulsmans M, Lavine KJ, Moreira MB, Heidt T, Courties G, Sun Y, Iwamoto Y, Tricot B, Khan OF, Dahlman JE, Borodovsky A, Fitzgerald K, Anderson DG, Weissleder R, Libby P, Swirski FK, …
• Beyond Medical "Missions" to Impact-Driven Short-Term Experiences in Global Health (STEGHs): Ethical Principles to Optimize Community Benefit and Learner Experience.
  Academic medicine : journal of the Association of American Medical Colleges 2016 Melby MK, Loh LC, Evert J, Prater C, Lin H, Khan OA
• Ex vivo cytosolic delivery of functional macromolecules to immune cells.
  PloS one 2015 Sharei A, Trifonova R, Jhunjhunwala S, Hartoularos GC, Eyerman AT, Lytton-Jean A, Angin M, Sharma S, Poceviciute R, Mao S, Heimann M, Liu S, Talkar T, Khan OF, Addo M, von Andrian UH, Anderson DG, …
• Challenges and opportunities in designing clinical trials for neuromyelitis optica.
  Neurology 2015 Weinshenker BG, Barron G, Behne JM, Bennett JL, Chin PS, Cree BA, de Seze J, Flor A, Fujihara K, Greenberg B, Higashi S, Holt W, Khan O, Knappertz V, Levy M, Melia AT, Palace J, Smith TJ, Sormani MP, …
• An ImmunoChip study of multiple sclerosis risk in African Americans.
  Brain : a journal of neurology 2015 Isobe N, Madireddy L, Khankhanian P, Matsushita T, Caillier SJ, Moré JM, Gourraud PA, McCauley JL, Beecham AH, International Multiple Sclerosis Genetics Consortium, Piccio L, Herbert J, Khan O, Cohen …
• Small RNA combination therapy for lung cancer.
  Proceedings of the National Academy of Sciences of the United States of America 2014 Xue W, Dahlman JE, Tammela T, Khan OF, Sood S, Dave A, Cai W, Chirino LM, Yang GR, Bronson R, Crowley DG, Sahay G, Schroeder A, Langer R, Anderson DG, Jacks T
• Lipid-like nanomaterials for simultaneous gene expression and silencing in vivo.
  Advanced healthcare materials 2014 Dong Y, Eltoukhy AA, Alabi CA, Khan OF, Veiseh O, Dorkin JR, Sirirungruang S, Yin H, Tang BC, Pelet JM, Chen D, Gu Z, Xue Y, Langer R, Anderson DG
• Advancing maternal survival in the global context: are our strategies working?
  BMC public health 2013 Khan OA, Derman R, Sloan NL
• Secondary T cell-T cell synaptic interactions drive the differentiation of protective CD8+ T cells.
  Nature immunology 2013 Gérard A, Khan O, Beemiller P, Oswald E, Hu J, Matloubian M, Krummel MF
• Global health education in U.S. medical schools.
  BMC medical education 2013 Khan OA, Guerrant R, Sanders J, Carpenter C, Spottswood M, Jones DS, O'Callahan C, Brewer TF, Markuns JF, Gillam S, O'Neill J, Nathanson N, Wright S
• Regulation of T cell priming by lymphoid stroma.
  PloS one 2011 Khan O, Headley M, Gerard A, Wei W, Liu L, Krummel MF
• Approaches to neuroprotective strategies in multiple sclerosis.
  Expert opinion on pharmacotherapy 2010 Tselis A, Khan OA, Lisak RP
• Refining the association of MHC with multiple sclerosis in African Americans.
  Human molecular genetics 2010 McElroy JP, Cree BA, Caillier SJ, Gregersen PK, Herbert J, Khan OA, Freudenberg J, Lee A, Bridges SL, Hauser SL, Oksenberg JR, Gourraud PA
• Genome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis.
  Nature 2010 Baranzini SE, Mudge J, van Velkinburgh JC, Khankhanian P, Khrebtukova I, Miller NA, Zhang L, Farmer AD, Bell CJ, Kim RW, May GD, Woodward JE, Caillier SJ, McElroy JP, Gomez R, Pando MJ, Clendenen LE, …
• Multiple sclerosis susceptibility alleles in African Americans.
  Genes and immunity 2009 Johnson BA, Wang J, Taylor EM, Caillier SJ, Herbert J, Khan OA, Cross AH, De Jager PL, Gourraud PA, Cree BC, Hauser SL, Oksenberg JR
• Intravenous immunoglobulin in relapsing-remitting multiple sclerosis: a dose-finding trial.
  Neurology 2009 Khan OA, Tselis A, Boster A
• Modification of Multiple Sclerosis Phenotypes by African Ancestry at HLA.
  Archives of neurology 2009 Cree BA, Reich DE, Khan O, De Jager PL, Nakashima I, Takahashi T, Bar-Or A, Tong C, Hauser SL, Oksenberg JR
• Pediatric-onset multiple sclerosis in African-American black and European-origin white patients.
  Pediatric neurology 2009 Boster AL, Endress CF, Hreha SA, Caon C, Perumal JS, Khan OA
• Uncoupling the roles of HLA-DRB1 and HLA-DRB5 genes in multiple sclerosis.
  Journal of immunology (Baltimore, Md. : 1950) 2008 Caillier SJ, Briggs F, Cree BA, Baranzini SE, Fernandez-Viña M, Ramsay PP, Khan O, Royal W, Hauser SL, Barcellos LF, Oksenberg JR
• Case report: an unusual presentation of multiple myeloma.
  Delaware medical journal 2008 Somani V, Khan OA
• Quantitative proton MRS of Pelizaeus-Merzbacher disease: evidence of dys- and hypomyelination.
  Neurology 2006 Khan OA
• Clinical characteristics of African Americans vs Caucasian Americans with multiple sclerosis.
  Neurology 2004 Cree BA, Khan O, Bourdette D, Goodin DS, Cohen JA, Marrie RA, Glidden D, Weinstock-Guttman B, Reich D, Patterson N, Haines JL, Pericak-Vance M, DeLoa C, Oksenberg JR, Hauser SL
• Mapping multiple sclerosis susceptibility to the HLA-DR locus in African Americans.
  American journal of human genetics 2003 Oksenberg JR, Barcellos LF, Cree BA, Baranzini SE, Bugawan TL, Khan O, Lincoln RR, Swerdlin A, Mignot E, Lin L, Goodin D, Erlich HA, Schmidt S, Thomson G, Reich DE, Pericak-Vance MA, Haines JL, Hauser…
• The global and local impact of malaria: a case report from Delaware, advances in treatment, and recommendations for travelers.
  Delaware medical journal 2003 Gilani JM, Khan OA
• Intercaudate nucleus ratio as a linear measure of brain atrophy in multiple sclerosis.
  Neurology 2003 Caon C, Zvartau-Hind M, Ching W, Lisak RP, Tselis AC, Khan OA
• A prospective, open-label treatment trial to compare the effect of IFNbeta-1a (Avonex), IFNbeta-1b (Betaseron), and glatiramer acetate (Copaxone) on the relapse rate in relapsing--remitting multiple sclerosis: results after 18 months of therapy.
  Multiple sclerosis (Houndmills, Basingstoke, England) 2001 Khan OA, Tselis AC, Kamholz JA, Garbern JY, Lewis RA, Lisak RP
• Effect of monthly intravenous cyclophosphamide in rapidly deteriorating multiple sclerosis patients resistant to conventional therapy.
  Multiple sclerosis (Houndmills, Basingstoke, England) 2001 Khan OA, Zvartau-Hind M, Caon C, Din MU, Cochran M, Lisak D, Tselis AC, Kamholz JA, Garbern JY, Lisak RP
• Responses to an emerging threat: HIV/AIDS policy in Pakistan.
  Health policy and planning 2001 Khan OA, Hyder AA
• A prospective, open-label treatment trial to compare the effect of IFN beta-1a (Avonex), IFNbeta-1b (Betaseron), and glatiramer acetate (Copaxone) on the relapse rate in relapsing-remitting multiple sclerosis.
  European journal of neurology 2001 Khan OA, Tselis AC, Kamholz JA, Garbern JY, Lewis RA, Lisak RP
• Topiramate relieves refractory trigeminal neuralgia in MS patients.
  Neurology 2000 Zvartau-Hind M, Din MU, Gilani A, Lisak RP, Khan OA
• Anaesthesia and saccadic eye movements.
  Anaesthesia 2000 Khan OA, Taylor SR, Jones JG
• Sub-national response in HIV/AIDS: a case study in AIDS prevention and control from Sindh province, Pakistan.
  Public health 1999 Hyder AA, Khan OA, Shah SA, Memon MA, Khanani MR, Ali S
• Neutralizing antibodies to interferon beta-1a and interferon beta-1b in MS patients are cross-reactive.
  Neurology 1998 Khan OA, Dhib-Jalbut SS
• HIV/AIDS in Pakistan: the context and magnitude of an emerging threat.
  Journal of epidemiology and community health 1998 Hyder AA, Khan OA
• Serum interferon beta-1a (Avonex) levels following intramuscular injection in relapsing-remitting MS patients.
  Neurology 1998 Khan OA, Dhib-Jalbut SS
• Gabapentin relieves trigeminal neuralgia in multiple sclerosis patients.
  Neurology 1998 Khan OA
• Incidence of exacerbations in the first 90 days of treatment with recombinant human interferon beta-1b in patients with relapsing-remitting multiple sclerosis.
  Annals of neurology 1998 Khan OA, Hebel JR
• Immunomodulating functions of recombinant ovine interferon tau: potential for therapy in multiple sclerosis and autoimmune disorders.
  Multiple sclerosis (Houndmills, Basingstoke, England) 1998 Khan OA, Jiang H, Subramaniam PS, Johnson HM, Dhib-Jalbut SS
• Concurrence of multiple sclerosis and brain tumor: clinical considerations.
  Neurology 1997 Khan OA, Bauserman SC, Rothman MI, Aldrich EF, Panitch HS
• Treatment with oral 3,4 diaminopyridine improves leg strength in multiple sclerosis patients: results of a randomized, double-blind, placebo-controlled, crossover trial.
  Neurology 1996 Bever CT, Anderson PA, Leslie J, Panitch HS, Dhib-Jalbut S, Khan OA, Milo R, Hebel JR, Conway KL, Katz E, Johnson KP
• Interferon beta-1b serum levels in multiple sclerosis patients following subcutaneous administration.
  Neurology 1996 Khan OA, Xia Q, Bever CT, Johnson KP, Panitch HS, Dhib-Jalbut SS
• Treatment of paroxysmal symptoms in multiple sclerosis with ibuprofen.
  Neurology 1994 Khan OA