Olga Zbodakova, PhD
Research Associate
Orofacial Sciences
School of Dentistry

Publications (9)

Top publication keywords:
Liver DiseasesInfluenza A virusNetherton SyndromePrimary Cell CultureLiver RegenerationChemokine CX3CL1KallikreinsLiverADAM10 ProteinSerine ProteasesAmyloid Precursor Protein SecretasesADAM17 ProteinZygoteMatrix Metalloproteinases, SecretedMembrane Proteins

• ADAM10 and ADAM17 regulate EGFR, c-Met and TNF RI signalling in liver regeneration and fibrosis.
  Scientific reports 2021 Zbodakova O, Chalupsky K, Sarnova L, Kasparek P, Jirouskova M, Gregor M, Sedlacek R
• Kallikrein-related peptidase 5 and seasonal influenza viruses, limitations of the experimental models for activating proteases.
  Biological chemistry 2018 Magnen M, Elsässer BM, Zbodakova O, Kasparek P, Gueugnon F, Petit-Courty A, Sedlacek R, Goettig P, Courty Y
• Profiling system for skin kallikrein proteolysis applied in gene-deficient mouse models.
  Biological chemistry 2018 Horn M, Zbodakova O, Kasparek P, Srp J, Haneckova R, Hradilek M, Mares M, Sedlacek R
• KLK5 and KLK7 Ablation Fully Rescues Lethality of Netherton Syndrome-Like Phenotype.
  PLoS genetics 2017 Kasparek P, Ileninova Z, Zbodakova O, Kanchev I, Benada O, Chalupsky K, Brattsand M, Beck IM, Sedlacek R
• A disintegrin and metalloprotease 10 (ADAM10) is a central regulator of murine liver tissue homeostasis.
  Oncotarget 2016 Müller M, Wetzel S, Köhn-Gaone J, Chalupsky K, Lüllmann-Rauch R, Barikbin R, Bergmann J, Wöhner B, Zbodakova O, Leuschner I, Martin G, Tiegs G, Rose-John S, Sedlacek R, Tirnitz-Parker JE, Saftig P, …

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• MMP-19 deficiency causes aggravation of colitis due to defects in innate immune cell function.
  Mucosal immunology 2015 Brauer R, Tureckova J, Kanchev I, Khoylou M, Skarda J, Prochazka J, Spoutil F, Beck IM, Zbodakova O, Kasparek P, Korinek V, Chalupsky K, Karhu T, Herzig KH, Hajduch M, Gregor M, Sedlacek R
• Efficient gene targeting of the Rosa26 locus in mouse zygotes using TALE nucleases.
  FEBS letters 2014 Kasparek P, Krausova M, Haneckova R, Kriz V, Zbodakova O, Korinek V, Sedlacek R
• Liver protective effect of ursodeoxycholic acid includes regulation of ADAM17 activity.
  BMC gastroenterology 2013 Buryova H, Chalupsky K, Zbodakova O, Kanchev I, Jirouskova M, Gregor M, Sedlacek R
• Hepatoprotective effect of MMP-19 deficiency in a mouse model of chronic liver fibrosis.
  PloS one 2012 Jirouskova M, Zbodakova O, Gregor M, Chalupsky K, Sarnova L, Hajduch M, Ehrmann J, Jirkovska M, Sedlacek R