Noel Cruz Pacheco
Staff Research Associate *
Dermatology
School of Medicine

Publications (14)

Top publication keywords:
TelomeraseNeuregulinsRadiation InjuriesSalivary GlandsMucous MembraneParaffin EmbeddingMelanomaAcinar CellsUltraviolet RaysOrganogenesisSalivary DuctsSOXB1 Transcription FactorsFormaldehydeMelanocytesSkin Neoplasms

• A Technique for the Generation of Mucosal and Acral Melanoma Cell Lines.
  Pigment cell & melanoma research 2026 Banik I, Basu S, Wang M, Escobar AJ, Steri V, Camara Serrano JA, Phojanakong P, Pacheco NC, Tsai KK, Alvarez EA, Daud A, El-Sayed IH, Samarkina A, Xu J, Aquino JD, Xiao M, Herlyn M, Yeh I
• Molecular effects of indoor tanning.
  Science advances 2025 Gerami P, Tandukar B, Deivendran D, Olivares S, Chen L, Tang J, Tan T, Sharma H, Bandari AK, Cruz-Pacheco N, Chang D, Marty AL, Olshen A, Murad NF, Song J, Lee J, Yeh I, Shain AH
• Genetic evolution of keratinocytes to cutaneous squamous cell carcinoma.
  Nature communications 2025 Tandukar B, Deivendran D, Chen L, Bandari AK, Cruz-Pacheco N, Sharma H, Wang M, Xu A, Chen DB, George CD, Marty AL, Cho RJ, Cheng JB, Saylor D, Gerami P, Yeh I, Arron ST, Bastian BC, Shain AH
• Somatic mutations distinguish melanocyte subpopulations in human skin.
  bioRxiv : the preprint server for biology 2025 Tandukar B, Deivendran D, Chen L, Bahrani N, Weier B, Sharma H, Cruz-Pacheco N, Hu M, Marks K, Zitnay RG, Bandari AK, Nekoonam R, Yeh I, Judson-Torres R, Shain AH
• The genetic evolution of acral melanoma.
  Nature communications 2024 Wang M, Fukushima S, Sheen YS, Ramelyte E, Cruz-Pacheco N, Shi C, Liu S, Banik I, Aquino JD, Sangueza Acosta M, Levesque M, Dummer R, Liau JY, Chu CY, Shain AH, Yeh I, Bastian BC

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• Molecular effects of indoor tanning.
  bioRxiv : the preprint server for biology 2024 Gerami P, Tandukar B, Deivendran D, Olivares S, Chen L, Tang J, Tan T, Sharma H, Bandari AK, Cruz-Pacheco N, Chang D, Marty A, Olshen A, Murad NF, Song J, Lee J, Yeh I, Hunter Shain A
• STmut: a framework for visualizing somatic alterations in spatial transcriptomics data of cancer.
  Genome biology 2023 Chen L, Chang D, Tandukar B, Deivendran D, Pozniak J, Cruz-Pacheco N, Cho RJ, Cheng J, Yeh I, Marine C, Bastian BC, Ji AL, Shain AH
• Long-term functional regeneration of radiation-damaged salivary glands through delivery of a neurogenic hydrogel.
  Science advances 2022 Li J, Sudiwala S, Berthoin L, Mohabbat S, Gaylord EA, Sinada H, Cruz Pacheco N, Chang JC, Jeon O, Lombaert IMA, May AJ, Alsberg E, Bahney CS, Knox SM
• Neuronal-epithelial cross-talk drives acinar specification via NRG1-ERBB3-mTORC2 signaling.
  Developmental cell 2022 May AJ, Mattingly AJ, Gaylord EA, Griffin N, Sudiwala S, Cruz-Pacheco N, Emmerson E, Mohabbat S, Nathan S, Sinada H, Lombaert IMA, Knox SM
• Diverse progenitor cells preserve salivary gland ductal architecture after radiation-induced damage.
  Development (Cambridge, England) 2018 May AJ, Cruz-Pacheco N, Emmerson E, Gaylord EA, Seidel K, Nathan S, Muench MO, Klein OD, Knox SM
• Salivary glands regenerate after radiation injury through SOX2-mediated secretory cell replacement.
  EMBO molecular medicine 2018 Emmerson E, May AJ, Berthoin L, Cruz-Pacheco N, Nathan S, Mattingly AJ, Chang JL, Ryan WR, Tward AD, Knox SM
• SOX2 regulates acinar cell development in the salivary gland.
  eLife 2017 Emmerson E, May AJ, Nathan S, Cruz-Pacheco N, Lizama CO, Maliskova L, Zovein AC, Shen Y, Muench MO, Knox SM
• Manipulating the murine lacrimal gland.
  Journal of visualized experiments : JoVE 2014 Finley JK, Farmer D, Emmerson E, Cruz Pacheco N, Knox SM
• Parasympathetic innervation regulates tubulogenesis in the developing salivary gland.
  Developmental cell 2014 Nedvetsky PI, Emmerson E, Finley JK, Ettinger A, Cruz-Pacheco N, Prochazka J, Haddox CL, Northrup E, Hodges C, Mostov KE, Hoffman MP, Knox SM