Noa Simchoni, MD, PhD
Clinical Instructor
Medicine
School of Medicine

Publications (16)

Top publication keywords:
Toll-Like Receptor 9PhenotypeCommon Variable ImmunodeficiencyLung Diseases, InterstitialJob SyndromeAgammaglobulinemiaGenetic Diseases, X-LinkedToll-Like Receptor 7B-LymphocytesImmunoglobulin MB-Lymphocyte SubsetsComplementarity Determining RegionsV(D)J RecombinationSomatic Hypermutation, ImmunoglobulinImmunoglobulin Heavy Chains

• Activated STING in the thymus alters T cell development and selection leading to autoimmunity.
  bioRxiv : the preprint server for biology 2024 Deng Z, Law CS, Kurra S, Simchoni N, Shum AK
• Pathogenic COPA mutations decrease binding of dilysine motifs through allosteric effects.
  Biophysical Journal 2024 Anna Pavlova, Sasthi C. Mandal, Noa Simchoni, Christopher S. Law, Atanu Acharya, Anthony K. Shum, James C. Gumbart
• COPA Syndrome from Diagnosis to Treatment: A Clinician's Guide.
  Rheumatic diseases clinics of North America 2023 Simchoni N, Vogel TP, Shum AK
• Implementation of Clinical Practice Guidelines for Hospitalized Patients With COVID-19 in Academic Medical Centers.
  JAMA network open 2022 Berger AC, Simchoni N, Auerbach A, Brode WM, Kuperman E, Raffel K, Kubey A, HOMERuN COVID-19 Collaborative Group
• AN UNUSUAL CASE OF INNUMERABLE LUNG NODULES.
  CHEST Journal 2019 Noa Simchoni, Lurit Bepo, Kaitlyn Tracy, Travis Zack

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• Microbiota regulate the ability of lung dendritic cells to induce IgA class-switch recombination and generate protective gastrointestinal immune responses.
  The Journal of experimental medicine 2015 Ruane D, Chorny A, Lee H, Faith J, Pandey G, Shan M, Simchoni N, Rahman A, Garg A, Weinstein EG, Oropallo M, Gaylord M, Ungaro R, Cunningham-Rundles C, Alexandropoulos K, Mucida D, Merad M, Cerutti A,…
• Expansion of inflammatory innate lymphoid cells in patients with common variable immune deficiency.
  The Journal of allergy and clinical immunology 2015 Cols M, Rahman A, Maglione PJ, Garcia-Carmona Y, Simchoni N, Ko HM, Radigan L, Cerutti A, Blankenship D, Pascual V, Cunningham-Rundles C
• High-throughput sequencing reveals an altered T cell repertoire in X-linked agammaglobulinemia.
  Clinical immunology (Orlando, Fla.) 2015 Ramesh M, Simchoni N, Hamm D, Cunningham-Rundles C
• IgH sequences in common variable immune deficiency reveal altered B cell development and selection.
  Science translational medicine 2015 Roskin KM, Simchoni N, Liu Y, Lee JY, Seo K, Hoh RA, Pham T, Park JH, Furman D, Dekker CL, Davis MM, James JA, Nadeau KC, Cunningham-Rundles C, Boyd SD
• Toll-like receptor signaling in primary immune deficiencies.
  Annals of the New York Academy of Sciences 2015 Maglione PJ, Simchoni N, Cunningham-Rundles C
• Biliary Epithelial Cells Are Not the Predominant Source of Hepatic CXCL12.
  The American journal of pathology 2015 Saiman Y, Sugiyama T, Simchoni N, Spirli C, Bansal MB
• TLR7- and TLR9-responsive human B cells share phenotypic and genetic characteristics.
  Journal of immunology (Baltimore, Md. : 1950) 2015 Simchoni N, Cunningham-Rundles C
• Clonal and constricted T cell repertoire in Common Variable Immune Deficiency.
  Clinical immunology (Orlando, Fla.) 2015 Ramesh M, Hamm D, Simchoni N, Cunningham-Rundles C
• IRAK-4 and MyD88 deficiencies impair IgM responses against T-independent bacterial antigens.
  Blood 2014 Maglione PJ, Simchoni N, Black S, Radigan L, Overbey JR, Bagiella E, Bussel JB, Bossuyt X, Casanova JL, Meyts I, Cerutti A, Picard C, Cunningham-Rundles C
• Selectivity of Toll-like receptor stimulation in human B cells (HUM8P.350).
  The Journal of Immunology 2014 Noa Simchoni, Charlotte Cunningam-Rundles
• Deep sequencing of the IgH locus in CVID reveals global alterations in central and peripheral B cell development (P3329).
  The Journal of Immunology 2013 Noa Simchoni, Krishna Roskin, Scott Boyd, Charlotte Cunningam-Rundles